Toothpaste with refreshing and whitening effects and preparation method thereof
By using compositions such as glucanase, papain, bromelain, superoxide dismutase and zinc citrate in toothpaste, the problem of limited functions of existing toothpaste in removing tooth stains and stains is solved, and the effect of teeth whitening and breathing is achieved.
Patent Information
- Application Number
- CN202510062884.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-15
- Publication Date
- 2025-04-15
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing toothpastes have limited functions in removing teeth stains and stains, making it difficult to meet the modern people's needs for oral whitening and freshness.
A toothpaste with whitening and refreshing effects is prepared using a composition with a refreshing and whitening effect, including glucanase, papain, bromelain, superoxide dismutase and zinc citrate, combined with a foaming agent, a friction agent, a thickener and water.
It achieves the whitening effect of teeth and the freshness of breath. The four enzyme components have a certain synergistic effect in terms of effects, significantly improving the cleaning and whitening effect of toothpaste.
Smart Images
Figure BDA0005243425490000101 
Figure BDA0005243425490000111
Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of daily necessities and relates to a toothpaste with refreshing and whitening effects and a preparation method thereof. Background Art
[0002] In modern society, people pay more and more attention to oral health and beauty. As a key product for daily oral care, toothpaste has attracted much attention for its function and quality. Diverse eating habits have led to a wide variety of food intake. Among them, dark foods and drinks such as coffee, tea, red wine and various sauces account for a considerable proportion of people's daily diet. These foods and drinks are rich in pigments, such as tannins in coffee, tea polyphenols in tea and anthocyanins in red wine. During consumption, these pigments are easily attached to the surface of teeth, forming spots and stains, causing the appearance of teeth to become yellow and dark, seriously affecting the beauty of teeth.
[0003] To sum up, based on the changes in people's eating habits, the improvement of aesthetic concepts and social needs, and the limitations of existing toothpaste products in the refreshing and whitening functions, the research and development of refreshing and whitening toothpaste with innovative formulas and excellent efficacy has broad market prospects and important social significance. Summary of the invention
[0004] In view of the deficiencies in the prior art, the object of the present invention is to provide a toothpaste with refreshing and whitening effects and a preparation method thereof.
[0005] In order to achieve the purpose of the invention, the present invention adopts the following technical solutions:
[0006] In a first aspect, the present invention provides a toothpaste with a refreshing and whitening effect. The raw materials for preparing the toothpaste include a composition with a refreshing and whitening effect, a foaming agent, an abrasive, a thickener and water. The composition with a refreshing and whitening effect includes glucanase, papain, bromelain, superoxide dismutase and zinc citrate.
[0007] The toothpaste prepared by the invention has the effects of whitening teeth and refreshing breath, and the glucanase, papain, bromelain and superoxide dismutase have a certain synergistic effect on the above effects.
[0008] Preferably, the raw materials for preparing the toothpaste include, by weight, 0.1-2 parts of a composition having a refreshing and whitening effect, 2-6 parts of a foaming agent, 17.5-21.5 parts of an abrasive, 1-3 parts of a thickener and 18-22 parts of water.
[0009] The mass parts of the composition can be selected from 0.1 parts, 0.2 parts, 0.5 parts, 0.8 parts, 1 parts, 1.2 parts, 1.5 parts, 1.8 parts, 2 parts, etc., the mass parts of the foaming agent can be selected from 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, 4.5 parts, 5 parts, 5.5 parts, 6 parts, etc., the mass parts of the friction agent can be selected from 17.5 parts, 18 parts, 18.5 parts, 19 parts, 19.5 parts, 20 parts, 20.5 parts, 21 parts, 21.5 parts, etc., the mass parts of the thickener can be selected from 1 part, 1.5 parts, 2 parts, 2.5 parts, 3 parts, etc., the mass parts of water can be selected from 18 parts, 18.5 parts, 19 parts, 19.5 parts, 20 parts, 20.5 parts, 21 parts, 21.5 parts, 22 parts, etc., and other specific point values within the above numerical range can be selected, so they will not be repeated here one by one.
[0010] Preferably, the composition with refreshing and whitening effect comprises, by weight, 0.0001-3 parts of glucanase, 0.01-3 parts of papain, 0.01-2 parts of bromelain, 0.01-2 parts of superoxide dismutase and 0.1-2 parts of zinc citrate.
[0011] The mass fraction of glucanase can be selected from 0.0001 parts, 0.001 parts, 0.003 parts, 0.005 parts, 0.008 parts, 0.01 parts, 0.05 parts, 0.08 parts, 0.1 parts, 0.2 parts, 0.5 parts, 0.8 parts, 1 parts, 1.2 parts, 1.5 parts, 1.8 parts, 2 parts, 2.2 parts, 2.5 parts, 2.8 parts, 3 parts, etc.; the mass fraction of papain can be selected from 0.01 parts, 0.05 parts, 0.08 parts, 0.1 parts, 0.2 parts, 0.5 parts, 1 parts, 1.2 parts, 1.5 parts, 1.8 parts, 2 parts, 2.2 parts, 2.5 parts, 2.8 parts, 3 parts, etc.; The mass fraction of enzyme can be selected from 0.01 parts, 0.05 parts, 0.08 parts, 0.1 parts, 0.2 parts, 0.5 parts, 1 parts, 1.2 parts, 1.5 parts, 1.8 parts, 2 parts, etc.; the mass fraction of superoxide dismutase can be selected from 0.01 parts, 0.05 parts, 0.08 parts, 0.1 parts, 0.2 parts, 0.5 parts, 1 parts, 1.2 parts, 1.5 parts, 1.8 parts, 2 parts, etc.; the mass fraction of zinc citrate can be selected from 0.1 parts, 0.2 parts, 0.5 parts, 0.8 parts, 1 parts, 1.2 parts, 1.5 parts, 1.8 parts, 2 parts, etc.; other specific point values within the above numerical range can be selected, which will not be repeated here one by one.
[0012] Preferably, the foaming agent comprises cocamidopropyl betaine and / or sodium lauryl sulfate.
[0013] Preferably, the thickener comprises xanthan gum and / or methyl hydroxyethyl cellulose.
[0014] Preferably, the abrasive comprises hydrated silica.
[0015] Preferably, the raw materials for preparing the toothpaste further include any one or a combination of at least two of a moisturizer, a fragrance, a chelating agent, a preservative, an anti-caries agent, a pH adjuster, a taste improver or a colorant.
[0016] Preferably, the raw materials for preparing the toothpaste further include, by weight, any one of 49-53 parts of moisturizer, 0.01-1.5 parts of fragrance, 1-4 parts of chelating agent, 0.5-3.5 parts of preservative, 0.2-2.8 parts of anti-caries agent, 0.1-3 parts of pH adjuster, 0.15-3.5 parts of taste improver or 0.5-2.5 parts of colorant, or a combination of at least two of them.
[0017] The mass fraction of the moisturizer can be selected from 49 parts, 49.5 parts, 50 parts, 50.5 parts, 51 parts, 51.5 parts, 52 parts, 52.5 parts, 53 parts, etc.; the mass fraction of the fragrance can be selected from 0.01 parts, 0.05 parts, 0.1 parts, 0.2 parts, 0.5 parts, 0.8 parts, 1 parts, 1.2 parts, 1.5 parts, etc.; the mass fraction of the chelating agent can be selected from 1 parts, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, 4 parts, etc.; the mass fraction of the preservative can be selected from 0.5 parts, 1 parts, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, etc.; the mass fraction of the anti-caries agent can be selected from 0.2 parts, 0.4 parts, 0.6 parts, 0.8 parts, 1 parts, 1.2 parts , 1.4 parts, 1.6 parts, 1.8 parts, 2 parts, 2.2 parts, 2.4 parts, 2.6 parts, 2.8 parts, etc., the mass fraction of pH adjuster can be selected from 0.1 parts, 0.2 parts, 0.5 parts, 0.8 parts, 1 parts, 1.2 parts, 1.5 parts, 1.8 parts, 2 parts, 2.2 parts, 2.5 parts, 2.8 parts, 3 parts, etc., the mass fraction of taste improver can be selected from 0.15 parts, 0.3 parts, 0.5 parts, 0.8 parts, 1 parts, 1.5 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts, etc., the mass fraction of colorant can be selected from 0.5 parts, 1 parts, 1.5 parts, 2 parts, 2.5 parts, etc., other specific point values within the above numerical range can be selected, so they will not be elaborated here one by one.
[0018] Preferably, the moisturizing agent includes any one of glycerin, sorbitol, polyethylene glycol-8, lysozyme, mannitol, sodium lactate, persimmon fruit extract or sodium hyaluronate, or a combination of at least two thereof.
[0019] Preferably, the fragrance comprises essence.
[0020] Preferably, the chelating agent comprises disodium dihydrogen pyrophosphate.
[0021] Preferably, the preservative comprises methylpropanediol and / or o-cymene-5-ol.
[0022] Preferably, the anticaries agent comprises sodium fluoride.
[0023] Preferably, the pH adjuster comprises sodium hydroxide.
[0024] Preferably, the taste improver comprises galactose.
[0025] Preferably, the colorant comprises titanium dioxide.
[0026] In a second aspect, the present invention provides a method for preparing the toothpaste with refreshing and whitening effects according to the first aspect, the preparation method comprising: physically mixing the preparation raw materials and defoaming to obtain the toothpaste.
[0027] Compared with the prior art, the present invention has the following beneficial effects:
[0028] The toothpaste prepared by the invention has the effects of whitening teeth and refreshing breath, and the glucanase, papain, bromelain and superoxide dismutase have a certain synergistic effect on the above effects. DETAILED DESCRIPTION
[0029] In order to further explain the technical means and effects adopted by the present invention, the technical solution of the present invention is further described below in conjunction with the preferred embodiments of the present invention, but the present invention is not limited to the scope of the embodiments.
[0030] The sources of the functional ingredients contained in the products involved in the following embodiments and comparative examples are as follows (only the functional ingredients are reflected, and the necessary auxiliary ingredients contained in other commercially available raw materials are not repeated):
[0031] Glucanase was purchased from Wuxi Yizhu Biotechnology Co., Ltd. under the trade name of Glucanase;
[0032] Papain was purchased from Nanning Dongheng Huadao Biotechnology Co., Ltd. under the trade name of papain;
[0033] Bromelain was purchased from Nanning Dongheng Huadao Biotechnology Co., Ltd. under the trade name Bromelain;
[0034] Superoxide dismutase was purchased from Nanning Dongheng Huadao Biotechnology Co., Ltd. under the trade name of superoxide dismutase (SOD);
[0035] Cocamidopropyl betaine was purchased from Guangzhou Tianci High-tech Materials Co., Ltd. under the trade name TC-CAB35GL;
[0036] Xanthan gum was purchased from Ordos Zhongxuan Biochemical Co., Ltd. under the trade name of xanthan gum RH;
[0037] Polyethylene glycol-8 was purchased from Clariant Chemical Technology (Shanghai) Co., Ltd. under the trade name Polyglykol 400C;
[0038] Lysozyme was purchased from Wuhan Heyuan Biotechnology Co., Ltd. under the trade name of plant-derived lysozyme;
[0039] Persimmon fruit extract was purchased from RILIS CO., LTD. under the trade name PANCILBA-200G-1;
[0040] The fragrance was purchased from Givaudan Fragrances & Fragrances (Shanghai) Co., Ltd. with the trade name of Pure Iris Upgraded Version AAN45287 / 01.
[0041] Example 1
[0042] The present embodiment provides a composition with refreshing and whitening effects, which comprises, by weight, 1 part of glucanase, 2 parts of papain, 1 part of bromelain, 1 part of superoxide dismutase and 1 part of zinc citrate.
[0043] The preparation method thereof is as follows: physically mixing the preparation raw materials to obtain the product.
[0044] Example 2
[0045] This embodiment provides a composition with refreshing and whitening effects, which comprises, by weight, 3 parts of glucanase, 0.01 parts of papain, 0.01 parts of bromelain, 2 parts of superoxide dismutase and 2 parts of zinc citrate.
[0046] The preparation method is similar to that of Example 1.
[0047] Example 3
[0048] The present embodiment provides a composition with refreshing and whitening effects, which comprises, by weight, 0.01 parts of glucanase, 3 parts of papain, 2 parts of bromelain, 0.01 parts of superoxide dismutase and 0.1 parts of zinc citrate.
[0049] The preparation method is similar to that of Example 1.
[0050] Comparative Example 1
[0051] This comparative example provides a composition with refreshing and whitening effects, which differs from Example 1 only in that it does not contain glucanase, and its reduced mass is proportionally distributed to the masses of papain, bromelain, and superoxide dismutase, while other components and contents remain unchanged.
[0052] The preparation method is similar to that of Example 1.
[0053] Comparative Example 2
[0054] This comparative example provides a composition with refreshing and whitening effects, which differs from Example 1 only in that papain is not contained, and its reduced mass is proportionally distributed to the masses of glucanase, bromelain, and superoxide dismutase, while other components and contents remain unchanged.
[0055] The preparation method is similar to that of Example 1.
[0056] Comparative Example 3
[0057] This comparative example provides a composition with refreshing and whitening effects, which differs from Example 1 only in that it does not contain bromelain, and its reduced mass is proportionally distributed to the masses of glucanase, papain, and superoxide dismutase, while other ingredients and contents remain unchanged.
[0058] The preparation method is similar to that of Example 1.
[0059] Comparative Example 4
[0060] This comparative example provides a composition with refreshing and whitening effects, which differs from Example 1 only in that it does not contain superoxide dismutase, and its reduced mass is proportionally distributed to the masses of glucanase, papain, and bromelain, while other components and contents remain unchanged.
[0061] The preparation method is similar to that of Example 1.
[0062] Comparative Example 5
[0063] This comparative example provides a composition with refreshing and whitening effects, which is different from Example 1 only in that it does not contain glucanase, papain, bromelain, and superoxide dismutase, and the reduced mass thereof is distributed to the mass of zinc citrate.
[0064] The preparation method is similar to that of Example 1.
[0065] Comparative Example 6
[0066] This comparative example provides a composition with refreshing and whitening effects, which differs from Example 1 only in that it does not contain zinc citrate, and its reduced mass is proportionally distributed to the masses of glucanase, papain, bromelain, and superoxide dismutase.
[0067] The preparation method is similar to that of Example 1.
[0068] Application Example 1
[0069] This application example provides a toothpaste with a refreshing and whitening effect, which includes, by mass, 0.5 parts of the composition with a refreshing and whitening effect of Example 1, 2 parts of cocamidopropyl betaine, 2 parts of sodium lauryl sulfate, 1 part of xanthan gum, 1 part of methyl hydroxyethyl cellulose, 19 parts of hydrated silica, 37 parts of glycerol, 2 parts of sorbitol, 1 part of polyethylene glycol-8, 2 parts of lysozyme, 2 parts of mannitol, 2 parts of sodium lactate, 2 parts of persimmon fruit extract, 2 parts of sodium hyaluronate, 1 part of flavor, 2 parts of disodium dihydrogen pyrophosphate, 0.8 parts of methylpropanediol, 0.8 parts of o-cymene-5-ol, 1.5 parts of sodium fluoride, 1 part of sodium hydroxide, 2 parts of trichlorogalactose, 1.5 parts of titanium dioxide and 20 parts of water.
[0070] The preparation method comprises the following steps: mixing the raw materials under the condition of 900 rpm, and defoaming to obtain the product.
[0071] Application Example 2
[0072] This application example provides a toothpaste with a refreshing and whitening effect, which includes, by mass, 0.1 parts of the composition with a refreshing and whitening effect of Example 2, 1 part of cocamidopropyl betaine, 1 part of sodium lauryl sulfate, 0.5 parts of xanthan gum, 0.5 parts of methyl hydroxyethyl cellulose, 21 parts of hydrated silica, 42 parts of glycerol, 1 part of sorbitol, 1 part of polyethylene glycol-8, 1 part of lysozyme, 1 part of mannitol, 1 part of sodium lactate, 1 part of persimmon fruit extract, 1 part of sodium hyaluronate, 1.5 parts of flavor, 4 parts of disodium dihydrogen pyrophosphate, 0.3 parts of methylpropanediol, 0.3 parts of o-cymene-5-ol, 0.3 parts of sodium fluoride, 0.1 parts of sodium hydroxide, 3.5 parts of trichlorogalactose, 2.5 parts of titanium dioxide and 22 parts of water.
[0073] The preparation method comprises the following steps: mixing the raw materials under the condition of 1000 rpm, and defoaming to obtain the product.
[0074] Application Example 3
[0075] This application example provides a toothpaste with a refreshing and whitening effect, which includes, by mass, 2 parts of the composition with a refreshing and whitening effect of Example 3, 3 parts of cocamidopropyl betaine, 3 parts of sodium lauryl sulfate, 1.5 parts of xanthan gum, 1.5 parts of methyl hydroxyethyl cellulose, 18 parts of hydrated silica, 46 parts of glycerol, 1 part of sorbitol, 1 part of polyethylene glycol-8, 1 part of lysozyme, 1 part of mannitol, 1 part of sodium lactate, 1 part of persimmon fruit extract, 1 part of sodium hyaluronate, 0.1 part of flavor, 1 part of disodium dihydrogen pyrophosphate, 1 part of methylpropanediol, 1 part of o-cymene-5-ol, 2 parts of sodium fluoride, 3 parts of sodium hydroxide, 0.2 parts of trichlorogalactose, 0.5 parts of titanium dioxide and 18 parts of water.
[0076] The preparation method comprises the following steps: mixing the raw materials at 800 rpm, and defoaming to obtain the product.
[0077] Comparative Application Examples 1-6
[0078] This comparative application example provides 6 toothpastes with refreshing and whitening effects, which differ from Application Example 1 only in that the composition with refreshing and whitening effects of Example 1 is replaced by the compositions of Comparative Examples 1-6 in equal amounts, and other ingredients and contents remain unchanged.
[0079] The preparation method refers to Application Example 1.
[0080] Test Example 1
[0081] Whitening effect test
[0082] Test method:
[0083] (1) Select a tooth without caries and clean and sterilize it.
[0084] (2) Soak the tooth block in 1% hydrochloric acid, saturated sodium carbonate, and 1% phytic acid alternately for 1 min each, rinse it clean, and place it in the prepared staining solution for 48 hours. The staining source used in this experiment is a mixture of black tea, coffee, soy sauce, and ferric chloride.
[0085] (3) Take out the tooth blocks from the staining solution, rinse them, dry them, and use a colorimeter to measure the whiteness value of the enamel surface of each tooth block, which is recorded as L before.
[0086] (4) The tooth blocks were randomly divided into groups, with 8 in each group, and analysis software was used to perform a difference test. No significant difference was found between the groups.
[0087] (5) The sample and water were mixed in a mass ratio of 1:3 to prepare toothpaste slurry. The tooth blocks of each group were simulated brushing with the same amount of toothpaste slurry for 3 days, twice a day.
[0088] (6) After rinsing the tooth block after simulating toothbrushing, dry it and use a colorimeter to measure the whiteness value of the enamel surface of the tooth block, which is recorded as L.
[0089] (7) Calculate the whiteness value difference △L before and after the simulated brushing respectively, and the calculation formula is as follows:
[0090] △L=L rear-L front
[0091] Table 1
[0092] △L Application Example 1 6.45 Application Example 2 6.04 Application Example 3 5.80 Comparative application example 1 3.93 Comparative Application Example 2 3.14 Comparative Application Example 3 2.97 Comparative Application Example 4 2.86 Comparative Application Example 5 1.97 Comparative Application Example 6 1.90
[0093] It can be seen from the data in Table 1 that the toothpaste prepared by the present invention has the effect of whitening teeth, and there is a certain synergistic effect between glucanase, papain, bromelain and superoxide dismutase, and none of the four components can be missing. The enzyme and zinc citrate also have a potential synergistic effect.
[0094] Test Example 2
[0095] Fresh breath effect test
[0096] Test principle: The main components of bad breath gas are volatile sulfides, including methyl mercaptan, hydrogen sulfide and dimethyl sulfide, which are produced by various reasons, about 90% of which come from the mouth. This experiment simulates the use of oral care products in vitro, cultivates the production of volatile sulfides in the oral saliva secretions of volunteers, and measures methyl mercaptan to evaluate the breath freshening effect.
[0097] Test method:
[0098] (1) Cultivating hydroxyapatite sheets overnight to form acquired biofilms;
[0099] (2) Control group: soaked in deionized water for 2 min, taken out and placed in a headspace bottle;
[0100] Sample group: soaked in toothpaste slurry for 2 minutes, taken out and placed in a headspace bottle;
[0101] Preparation method of toothpaste slurry: Mix the sample with water in a mass ratio of 1:3;
[0102] (3) Mix saliva with thioglycollate medium, and mix the hydroxyapatite sheets of the control group and the experimental group with 3 mL of saliva medium;
[0103] (4) Incubate overnight for 12 h and detect the methyl mercaptan peak area.
[0104] Table 2
[0105]
[0106]
[0107] It can be seen from the data in Table 2 that the toothpaste prepared by the present invention has the effect of refreshing breath, and there is a certain synergistic effect between glucanase, papain, bromelain and superoxide dismutase. The four ingredients are indispensable, and the enzyme and zinc citrate also have potential synergistic effects.
[0108] The applicant declares that the present invention uses the above-mentioned embodiments to illustrate a toothpaste with refreshing and whitening effects and a preparation method thereof, but the present invention is not limited to the above-mentioned embodiments, that is, it does not mean that the present invention must rely on the above-mentioned embodiments to be implemented. Those skilled in the art should understand that any improvement of the present invention, equivalent replacement of various raw materials of the product of the present invention, addition of auxiliary ingredients, selection of specific methods, etc., all fall within the protection scope and disclosure scope of the present invention.
[0109] The preferred embodiments of the present invention are described in detail above. However, the present invention is not limited to the specific details in the above embodiments. Within the technical concept of the present invention, a variety of simple modifications can be made to the technical solution of the present invention, and these simple modifications all belong to the protection scope of the present invention.
[0110] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present invention will not further describe various possible combinations.
Claims
1. A toothpaste with a refreshing and whitening effect, characterized in that: The raw materials for preparing the toothpaste include a composition with refreshing and whitening effects, a foaming agent, an abrasive, a thickener and water. The composition with refreshing and whitening effects includes glucanase, papain, bromelain, superoxide dismutase and zinc citrate.
2. The toothpaste with refreshing and whitening effect according to claim 1, characterized in that: The raw materials for preparing the toothpaste include, by weight, 0.1-2 parts of a composition having a refreshing and whitening effect, 2-6 parts of a foaming agent, 17.5-21.5 parts of an abrasive, 1-3 parts of a thickener, and 18-22 parts of water; Preferably, the composition with refreshing and whitening effect comprises, by weight, 0.0001-3 parts of glucanase, 0.01-3 parts of papain, 0.01-2 parts of bromelain, 0.01-2 parts of superoxide dismutase and 0.1-2 parts of zinc citrate.
3. The toothpaste with refreshing and whitening effect according to claim 1 or 2, characterized in that: The foaming agent includes cocamidopropyl betaine and / or sodium lauryl sulfate; Preferably, the thickener comprises xanthan gum and / or methyl hydroxyethyl cellulose; Preferably, the abrasive comprises hydrated silica.
4. The toothpaste with refreshing and whitening effect according to any one of claims 1 to 3, characterized in that: The raw materials for preparing the toothpaste further include any one of a moisturizer, a fragrance, a chelating agent, a preservative, an anti-caries agent, a pH regulator, a taste improver or a colorant, or a combination of at least two of them.
5. The toothpaste with refreshing and whitening effect according to claim 4, characterized in that: The raw materials for preparing the toothpaste also include, by weight, any one of 49-53 parts of moisturizer, 0.01-1.5 parts of fragrance, 1-4 parts of chelating agent, 0.5-3.5 parts of preservative, 0.2-2.8 parts of anti-caries agent, 0.1-3 parts of pH adjuster, 0.15-3.5 parts of taste improver or 0.5-2.5 parts of colorant, or a combination of at least two of them.
6. The toothpaste with refreshing and whitening effect according to claim 4 or 5, characterized in that: The moisturizing agent includes any one or a combination of at least two of glycerin, sorbitol, polyethylene glycol-8, lysozyme, mannitol, sodium lactate, persimmon fruit extract or sodium hyaluronate; Preferably, the fragrance comprises essence.
7. The toothpaste with refreshing and whitening effect according to any one of claims 4 to 6, characterized in that: The chelating agent includes disodium dihydrogen pyrophosphate; Preferably, the preservative comprises methylpropanediol and / or o-cymene-5-ol; Preferably, the anticaries agent comprises sodium fluoride.
8. The toothpaste with refreshing and whitening effect according to any one of claims 4 to 7, characterized in that: The pH adjuster includes sodium hydroxide; Preferably, the taste improver comprises galactose.
9. The toothpaste with refreshing and whitening effect according to any one of claims 4 to 8, characterized in that: The colorant includes titanium dioxide.
10. A method for preparing a toothpaste with a refreshing and whitening effect according to any one of claims 1 to 9, characterized in that: The preparation method comprises: physically mixing the preparation raw materials and defoaming to obtain the product.