Feed additive capable of relieving animal hair falling and preparation method thereof

Abstract

The invention relates to the technical field of pet feed additives, and discloses a feed additive capable of relieving animal hair falling and a preparation method of the feed additive capable of relieving animal hair falling. Comprising the following substances: 5 parts of an angelica sinensis extract, 10 parts of a cacumen biotae extract, 1.51 parts of vitamin B family, 0.1 part of vitamin H, 1 part of zinc, 0.1 part of selenium, 5 parts of methionine and 5 parts of cysteine. According to the feed additive capable of relieving animal hair falling, the hair quality can be improved, and hair falling can be reduced; the strength and the elasticity of hair are improved; healthy hair growth is promoted; the composition has the advantages that the health of the skin and hair follicles is enhanced, a better growth environment is provided for the hair, the healthy hair state of animals can be maintained, and the hair loss phenomenon caused by nutrition deficiency or environmental problems is reduced.

Description

Technical Field

[0001] The invention relates to the technical field of pet feed additives, and in particular to a feed additive capable of alleviating animal hair loss and a preparation method thereof. Background Art

[0002] Pets refer to creatures that people keep for spiritual purposes rather than economic purposes. Traditional pets refer to animals of the class mammals or birds, which are kept for entertainment and companionship. Pets in real life include fish, reptiles, amphibians, insects, and even plants, which are used for viewing, companionship, and to relieve people's mental stress. The types of pets are all-encompassing, and according to zoological classification, they can be divided into: mammalian pets, reptile pets, bird pets, fish pets, and insect pets.

[0003] Mammals are warm-blooded, viviparous vertebrates that are found almost all over the world. There are many types of mammalian pets, which account for a large number and proportion of pets. Representative mammalian pets include dogs, cats, mice, rabbits, horses, cows, sheep, etc., which are divided into three types: herbivorous, carnivorous and omnivorous. Mammalian pets are characterized by developed brains, sensitive nerves and sensitive senses, and good learning ability. Because their IQ is higher than other species, they interact better with their owners and can understand their owners' ideas, making them very suitable as life partners. Mammalian pets are less dependent on the external environment and can adapt well to the environment.

[0004] In 2023, the number of pet dogs and pet cats in China will reach 51.75 million and 69.8 million respectively, totaling 120 million. The problem of animal hair loss has become an increasingly serious problem. Hair loss not only affects the appearance and health of animals, but may also have adverse effects on environmental hygiene and the growth and development of animals. Therefore, how to effectively reduce animal hair loss has become an important issue that pet owners need to solve urgently.

[0005] Existing solutions mainly solve the problem of animal hair loss through products such as vitamins, fish oil, lecithin, etc. However, the effects of most of these products are unstable, and most of them can only play an auxiliary role, making it difficult to fundamentally solve the problem of animal hair loss. Summary of the invention

[0006] In view of the above existing solutions mainly using vitamins, fish oil, lecithin and other products to solve the problem of animal hair loss, however, most of these products have unstable effects and most of them can only play an auxiliary role, and it is difficult to fundamentally solve the problem of animal hair loss, the present invention is proposed.

[0007] Therefore, the purpose of the present invention is to provide a feed additive that can alleviate animal hair loss, and its purpose is: According to our research, the most fundamental reason affecting animal hair loss is the lack of nutrition in the hair follicles, which causes the hair follicles to atrophy and close, and the hair enters the resting phase faster. Therefore, we have developed a feed additive that can improve subcutaneous blood circulation, dilate blood vessels, promote the absorption of nutrients by hair follicles, maintain the healthy growth of hair, and fundamentally alleviate the problem of pet hair loss.

[0008] To solve the above technical problems, the present invention provides the following technical solutions: a feed additive that can alleviate animal hair loss, comprising the following substances: 5 parts of angelica extract, 10 parts of Platycladus orientalis leaf extract, 1.51 parts of B vitamins, 0.1 part of vitamin H, 1 part of zinc, 0.1 part of selenium, 5 parts of methionine, and 5 parts of cysteine.

[0009] As a preferred embodiment of the feed additive capable of alleviating animal hair loss according to the present invention, the B vitamins include the following substances by weight: 0.5 parts of vitamin B1, 0.5 parts of vitamin B2, 0.5 parts of vitamin B6, and 0.01 parts of vitamin B12.

[0010] As a preferred embodiment of the feed additive capable of alleviating animal hair loss according to the present invention, the feed additive further comprises 0.5 parts of niacin and 0.1 parts of folic acid.

[0011] To achieve the above object, the present invention provides the following technical solution: a method for preparing a feed additive capable of alleviating animal hair loss, comprising the following steps:

[0012] Step 1, preparation of angelica extract, using solvent extraction method, generally using 80%-95% ethanol or water-ethanol mixed solvent for extraction, firstly cut the angelica into small pieces, add it to the solvent for soaking, then heat and reflux for extraction, and concentrate the extract. The concentrated extract can be converted into powder by spray drying or vacuum drying to facilitate subsequent addition;

[0013] Step 2, extracting the effective ingredients (such as flavonoids, tannic acid, etc.) from the Platycladus orientalis leaves by using water extraction or alcohol extraction (commonly 70% ethanol extraction) through soaking, reflux extraction and other steps, and concentrating the extract by evaporation, removing the solvent, and then spray drying or freeze drying to obtain a dry Platycladus orientalis leaf extract powder;

[0014] Step 3: Vitamin B1, B2 and B6 are then usually produced through a microbial fermentation process, using specific strains (such as yeast) for fermentation, and then filtered and concentrated to obtain a high-purity vitamin powder;

[0015] Step 4: Vitamin H is obtained by chemical synthesis through a specific organic synthesis reaction to ensure its high purity. The synthesized biotin is purified to obtain the final product, and the synthesized vitamin H is dried to form a powder, which is convenient for mixing with other ingredients;

[0016] Step 5. Common forms of zinc (such as zinc sulfate) can be extracted from a zinc source by chemical precipitation. Usually, a zinc source is reacted with sulfuric acid to obtain zinc sulfate, which is then dried to form a powder. Zinc sometimes exists in the form of a protein complex (such as a zinc protein complex). This zinc complex is formed by combining zinc ions with amino acids and proteins through a solution reaction.

[0017] Step 6: Selenium is often added in the form of selenium yeast (rich in organic selenium) or selenoprotein. Selenium yeast can be prepared by microbial fermentation, using a selenium-enriched culture medium and a microbial (such as yeast) fermentation process to convert inorganic selenium into organic selenium (selenium yeast). The obtained selenium yeast is dried to obtain a selenium-rich powder;

[0018] Step 7: Methionine is generally obtained by chemical synthesis, most commonly through the methionine synthesis pathway, and the synthesized methionine is purified to obtain high-quality powder;

[0019] Step 8: Cysteine ​​is usually prepared by fermentation or chemical synthesis, most commonly in the form of L-cysteine. The fermentation method uses a specific strain of bacteria for production, while chemical synthesis obtains cysteine ​​through a synthetic route. After purification by processes such as crystallization or membrane filtration, the final cysteine ​​powder is obtained;

[0020] Step nine, then put the angelica extract powder, Platycladus orientalis leaf extract powder, vitamin B powder, vitamin H powder, zinc powder, selenium powder, methionine powder, cysteine ​​powder, niacin and folic acid prepared in steps one to eight into a mixing device for mixing, and finally form a feed additive.

[0021] The beneficial effects of the present invention are as follows: the feed additive can improve hair quality and reduce hair loss; enhance hair strength and elasticity; promote healthy hair growth; enhance the health of skin and hair follicles, and provide a better growth environment for hair, which will help animals maintain a healthy hair state and reduce hair loss caused by lack of nutrition or environmental problems. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative labor. Among them:

[0023] Figure 1 It is a standard table of stool scoring of the present invention.

[0024] Figure 2 It is a standard chart for judging coat condition of the present invention.

[0025] Figure 3 It is a measurement chart of the hair loss test of the present invention.

[0026] Figure 4 It is the influence chart of the feeding characteristics of pet cats of the present invention.

[0027] Figure 5 This is a diagram showing the impact of pet cat feces on the present invention.

[0028] Figure 6 This is a diagram showing the effects of the sensory indexes of pet cat fur according to the present invention.

[0029] Figure 7 It is a schematic diagram of the sensory comparison of cat hair during the test period of the present invention.

[0030] Figure 8 A graph showing the results of the physical and chemical properties of pet cat fur according to the present invention.

[0031] Fig. 9 The second figure is the result of the physical and chemical properties of the pet cat's fur of the present invention.

[0032] Fig.10 Three figures are the results of the physical and chemical properties of pet cat fur of the present invention.

[0033] Fig.11 This is a comparison chart of cat hair length during the test period of the present invention.

[0034] Fig.12 It is a comparison chart of the fineness of cat coat during the test period of the present invention.

[0035] Fig.13 This is a comparison chart of cat hair loss during the test period of the present invention.

[0036] Fig.14 It is a comparison chart of cat coat density during the test period of the present invention. DETAILED DESCRIPTION

[0037] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0038] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0039] Example 1

[0040] Provided is a feed additive capable of alleviating animal hair loss, the feed additive capable of alleviating animal hair loss comprises the following substances by weight:

[0041] 5 parts of Chinese Angelica Extract (has the functions of regulating immunity, nourishing qi and blood, and promoting blood circulation, which helps to improve the overall health of animals and enhance the growth environment of hair);

[0042] 10 parts of Platycladus orientalis leaf extract (a traditional Chinese herbal medicine that promotes hair growth and enhances nutrition of hair roots, and is often used to prevent and treat hair loss);

[0043] Vitamin B group 1.51 parts;

[0044] 0.1 part of vitamin H (promotes healthy hair growth, enhances hair toughness and luster, reduces hair loss, and contributes to scalp health);

[0045] 1 part of zinc (zinc plays an important role in animals, promoting protein synthesis, enhancing immunity, and helping hair growth and repair. Zinc can also regulate sebum secretion and avoid hair loss caused by dry skin);

[0046] 0.1 part of selenium (has a strong antioxidant effect, can effectively protect hair from free radical damage, and enhance hair toughness and growth cycle);

[0047] 5 parts of methionine (provides the necessary nutrition for hair growth and enhances the strength and elasticity of hair);

[0048] 5 parts of cysteine ​​(promotes hair health while preventing hair brittleness and breakage).

[0049] The vitamin B complex includes the following substances by weight:

[0050] Vitamin B1: 0.5 parts (thiamine is an important water-soluble vitamin that is mainly involved in energy metabolism, especially carbohydrate metabolism. It helps convert carbohydrates into energy and supports the health of the nervous system);

[0051] Vitamin B2 0.5 parts (Riboflavin is a key coenzyme in the metabolism of fats, carbohydrates and proteins, helping cells produce energy. It is also involved in antioxidant processes and supports cell repair and regeneration);

[0052] Vitamin B6: 0.5 parts (pyridoxine plays an important role in protein metabolism, neurotransmitter synthesis, and red blood cell production. It is also involved in regulating the function of the immune system);

[0053] Vitamin B12 is 0.01 parts (cobalamin is a vitamin necessary for the production of red blood cells and is also involved in the health of the nervous system. It helps to increase metabolism and promote cell regeneration).

[0054] The feed additive also includes:

[0055] 0.5 parts of niacin (niacin plays an important role in energy metabolism and is involved in the synthesis of many important molecules, such as hormones, cholesterol, fatty acids, etc. It is also essential for skin health);

[0056] 0.1 parts of folic acid (folic acid is mainly involved in DNA synthesis and cell division, and is very important for tissue repair and the generation of new cells).

[0057] A method for preparing a feed additive capable of alleviating animal hair loss comprises the following steps:

[0058] Step 1, preparation of angelica extract, using solvent extraction method, generally using 80%-95% ethanol or water-ethanol mixed solvent for extraction, firstly cut the angelica into small pieces, add it to the solvent for soaking, then heat and reflux for extraction, and concentrate the extract. The concentrated extract can be converted into powder by spray drying or vacuum drying to facilitate subsequent addition;

[0059] Step 2, extracting the effective ingredients (such as flavonoids, tannic acid, etc.) from the Platycladus orientalis leaves by using water extraction or alcohol extraction (commonly 70% ethanol extraction) through soaking, reflux extraction and other steps, and concentrating the extract by evaporation, removing the solvent, and then spray drying or freeze drying to obtain a dry Platycladus orientalis leaf extract powder;

[0060] Step 3: Vitamin B1, B2 and B6 are then usually produced through a microbial fermentation process, using specific strains (such as yeast) for fermentation, and then filtered and concentrated to obtain a high-purity vitamin powder;

[0061] Step 4: Vitamin H is obtained by chemical synthesis through a specific organic synthesis reaction to ensure its high purity. The synthesized biotin is purified to obtain the final product. The synthesized vitamin H is dried to form a powder for easy mixing with other ingredients.

[0062] Step 5. Common forms of zinc (such as zinc sulfate) can be extracted from a zinc source by chemical precipitation. Usually, a zinc source is reacted with sulfuric acid to obtain zinc sulfate, which is then dried to form a powder. Zinc sometimes exists in the form of a protein complex (such as a zinc protein complex). This zinc complex is formed by combining zinc ions with amino acids and proteins through a solution reaction.

[0063] Step 6: Selenium is often added in the form of selenium yeast (rich in organic selenium) or selenoprotein. Selenium yeast can be prepared by microbial fermentation, using a selenium-enriched culture medium and a microbial (such as yeast) fermentation process to convert inorganic selenium into organic selenium (selenium yeast). The obtained selenium yeast is dried to obtain a selenium-rich powder;

[0064] Step 7: Methionine is generally obtained by chemical synthesis, most commonly through the methionine synthesis pathway, and the synthesized methionine is purified to obtain high-quality powder;

[0065] Step 8: Cysteine ​​is usually prepared by fermentation or chemical synthesis, most commonly in the form of L-cysteine. The fermentation method uses a specific strain of bacteria for production, while chemical synthesis obtains cysteine ​​through a synthetic route. After purification by processes such as crystallization or membrane filtration, the final cysteine ​​powder is obtained;

[0066] Step nine, then put the angelica extract powder, Platycladus orientalis leaf extract powder, vitamin B powder, vitamin H powder, zinc powder, selenium powder, methionine powder, cysteine ​​powder, niacin and folic acid prepared in steps one to eight into a mixing device for mixing, and finally form a feed additive.

[0067] Effect Experiment

[0068] 1. Experimental Design

[0069] The test period was 28 days. During the test period, 20 healthy Linqing lion cats were selected, weighing 3.21±0.51kg, and the sex was randomized. They were fed 100g of Yimeimei cat food. Each cat was kept in a single cage in a pet cat cage (1.6m×0.7m×0.7m). Necessary immunization and deworming were carried out before the test. The cat litter was changed every day, and the enclosure was cleaned and maintained clean.

[0070] During the test period, each cat was fed 100g of cat food and 300mL of water at 8:30 every morning. During the test period, the feeding status and mental state of all pets were observed to see if there were any adverse reactions such as disgust, diarrhea, and vomiting.

[0071] 2. Growth performance measurement

[0072] The fasting test cats were weighed before the experiment and on the 28th day of the experiment. The food intake and water intake of the test cats were recorded before morning feeding every day, and the average daily food intake and average daily water intake of all test cats were calculated after the end of the experiment.

[0073] 3. Gut health measurement

[0074] 3.1 Stool scoring

[0075] Before feeding each day, refer to Table 1 to score the appearance of each pet cat's feces (see Figure 1 fecal scoring standard table).

[0076] 4. Determination of fur index

[0077] On the first and 28th days of the test, multiple samples were collected to evaluate the fur of the pet cats (hair brightness, hair smoothness, skin elasticity), coat length, coat fineness, coat color difference (L*, a*, b*), coat elastic recovery rate, coat elongation, hair loss weight, coat density and other indicators. The lowest value on the first day was compared with the highest value on the 28th day;

[0078] 4.1 Sensory evaluation of coat

[0079] Three professionals conducted a random double-blind sensory evaluation of the animal's coat, and the scoring criteria were based on Figure 2 Standard table for judging coat condition.

[0080] 4.2 Coat sampling

[0081] Use pet-specific electric clippers to shave the hair off the left and right sides of the middle of each cat's back, close to the skin, and put them into sealed bags and store them with numbers.

[0082] 4.3 Determination of fur indexes

[0083] Use NR20XE colorimeter to measure the color difference of the hair in the middle of the cat's back (brightness value L*, redness value a*, yellowness value b*) close to the coat. The middle of the back is defined as the intersection of the highest point of the animal's two shoulder blades and the midline of the back;

[0084] The length of the coat can be measured by hand arrangement. Randomly select a section of hair sample, the weight of each sample is about 0.40-0.60g. First, use the hand-pulling method to preliminarily arrange the sample into a relatively neat hair bundle at one end, and then stack it on a black velvet board according to the length of the fiber to form a neat hair bundle at one end. Use a ruler to measure the length of the coat and take the average value.

[0085] The fineness of the hair is measured by the projection diameter method, that is, the hair is arranged neatly, cut into small sections of 1 cm, a small section is placed on a glass slide, cedar oil is added to fix it, and the hair is spread out with tweezers so that they do not overlap, and then a coverslip is slowly placed on the hair for observation under a microscope. The fineness of the hair is measured under a microscope.

[0086] The elastic recovery and elongation of the coat can be measured by a single fiber strength meter, and the fixed-length elasticity and fixed-load stretching can be measured, and the results are averaged.

[0087] 4.4 Coat density

[0088] The hair density in the middle of the back represents the hair density of the whole body, and the hair density is calculated by specific gravity. According to the length and width of the shaved area, calculate the area S, use a precision balance (accuracy 0.1mg) to accurately weigh the collected hair sample, and record the data M. Randomly select about 1 to 3mg of hair sample as the analysis sample and weigh it, record the data m1; use ophthalmic tweezers and a magnifying glass to count the number of hair fibers in the analysis sample one by one, and record the data W1; calculate the hair density according to the following formula:

[0089]

[0090] 4.5 Hair loss test

[0091] Select a certain area of ​​hair on both sides of the middle back, measure the time and combing times according to Table 3, use a comb to comb the area repeatedly along the hair, collect the fallen hair, weigh it with a 1 / 10,000 precision balance and record it (such as Figure 3 The figure shows the measurement chart of the hair loss test)

[0092] 5. Test results

[0093] 5.1 Effects on the feeding performance of pet cats

[0094] Observable Figure 4 The weight of the test cats in the table increased significantly, and their daily feed intake and water intake were within the normal range.

[0095] 5.2 Effects on the intestinal health of pet cats

[0096] refer to Figure 5 From the pet cat feces impact result chart, we can see that the test cat feces score is within the normal score range.

[0097] 5.3 Impact on the fur health of pet cats

[0098] 5.3.1 Effects on sensory indicators of pet cat fur

[0099] For reference Figure 6As shown in the table, the coat gloss, softness and skin elasticity of the test cats on the 28th day were significantly higher than those on the 1st day (P < 0.05). Figure 7 As shown, the test cats' hair was bright in color and soft to the touch on the first day. On the 28th day, the test cats' hair had improved luster and was softer and smoother to the touch.

[0100] 5.3.2 Effects on the physical and chemical properties of pet cat fur

[0101] refer to Figure 8 It can be seen that the coat L* (brightness value), coat a* (redness value), coat b* (yellowness value), coat elastic recovery rate, and coat elongation rate of the test cats on the 28th day were significantly higher than those on the 1st day (P < 0.05), and the coat fineness of the test cats on the 28th day was significantly lower than that on the 1st day (P < 0.05);

[0102] Depend on Fig. 9 , Fig.10 It can be seen that there was no significant difference in hair loss weight and coat density of the experimental cats on the first and 28th days (P>0.05);

[0103] Fig.11 There was no significant difference in the hair length of the test cats on the first day and the 28th day. Fig.12 In the experiment, the hair scales of the cats were smooth and neatly arranged on the 1st and 28th days. Fig.13 There was no significant difference in the amount of hair loss between the first day and the 28th day in the test cats. Fig.14 There was no significant difference in the coat density of the experimental cats on the 1st day and the 28th day.

[0104] 6. Conclusion

[0105] By mixing the feed additive with cat food, and then studying the effect on the fur health of pet cats, and feeding the pet cats with Yimeimei cat food for 28 days, the following conclusions were obtained:

[0106] 1) Feeding cat food with this feed additive will not affect the weight, food intake, and water intake of pet cats;

[0107] 2) Feeding cat food with this feed additive will not have an adverse effect on pet cat feces, and fecal scores are all within the normal range;

[0108] 3) The cat food fed with the feed additive has an impact on the sensory indicators of pet cats' fur, which can improve the glossiness, softness and skin elasticity of pet cats' fur, improve the dry and rough condition of pet cats' fur, and make the fur softer and smoother;

[0109] 4) The coat L* (brightness value), coat a* (redness value), coat b* (yellowness value), coat elastic recovery rate, and coat elongation rate of pet cats fed with cat food containing the feed additive were significantly improved, and the fineness of the pet cat's coat was reduced, indicating that the quality of pet cat's coat can be improved, the brightness and softness of the coat can be enhanced, and the health of the coat can be protected.

[0110] 5) The hair loss weight of cats fed with this feed additive from the 0th day to the 28th day was significantly reduced, which has the effect of delaying hair loss and stabilizing hair follicles.

[0111] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the spirit and scope of the technical solutions of the present invention, which should all be included in the scope of the claims of the present invention.

Claims

1. A feed additive that can alleviate animal hair loss, characterized in that: The feed additive comprises the following substances by weight: 5 parts of angelica extract, 10 parts of Platycladus orientalis leaf extract, 1.51 parts of B vitamins, 0.1 part of vitamin H, 1 part of zinc, 0.1 part of selenium, 5 parts of methionine and 5 parts of cysteine.

2. The feed additive capable of alleviating animal hair loss according to claim 1, characterized in that: The vitamin B complex includes the following substances by weight: The content of vitamin B1 is 0.5 part, vitamin B2 is 0.5 part, vitamin B6 is 0.5 part and vitamin B12 is 0.01 part.

3. The feed additive capable of alleviating animal hair loss according to claim 2, characterized in that: The feed additive also includes 0.5 parts of niacin and 0.1 parts of folic acid.

4. A method for preparing a feed additive capable of alleviating animal hair loss, which is applied to the feed additive capable of alleviating animal hair loss as claimed in claim 3, characterized in that: The following steps are involved: Step 1, preparation of angelica extract, using solvent extraction method, generally using 80%-95% ethanol or water-ethanol mixed solvent for extraction, firstly cut the angelica into small pieces, add it to the solvent for soaking, then heat and reflux for extraction, and concentrate the extract. The concentrated extract can be converted into powder by spray drying or vacuum drying to facilitate subsequent addition; Step 2, extracting the effective ingredients (such as flavonoids, tannic acid, etc.) from the Platycladus orientalis leaves by using water extraction or alcohol extraction (commonly 70% ethanol extraction) through soaking, reflux extraction and other steps, and concentrating the extract by evaporation, removing the solvent, and then spray drying or freeze drying to obtain a dry Platycladus orientalis leaf extract powder; Step 3: Vitamin B1, B2 and B6 are then usually produced through a microbial fermentation process, using specific strains (such as yeast) for fermentation, and then filtered and concentrated to obtain a high-purity vitamin powder; Step 4: Vitamin H is obtained by chemical synthesis through a specific organic synthesis reaction to ensure its high purity. The synthesized biotin is purified to obtain the final product, and the synthesized vitamin H is dried to form a powder, which is convenient for mixing with other ingredients; Step 5. Common forms of zinc (such as zinc sulfate) can be extracted from a zinc source by chemical precipitation. Usually, a zinc source is reacted with sulfuric acid to obtain zinc sulfate, which is then dried to form a powder. Zinc sometimes exists in the form of a protein complex (such as a zinc protein complex). This zinc complex is formed by combining zinc ions with amino acids and proteins through a solution reaction. Step 6: Selenium is often added in the form of selenium yeast (rich in organic selenium) or selenoprotein. Selenium yeast can be prepared by microbial fermentation, using a selenium-enriched culture medium and a microbial (such as yeast) fermentation process to convert inorganic selenium into organic selenium (selenium yeast). The obtained selenium yeast is dried to obtain a selenium-rich powder; Step 7: Methionine is generally obtained by chemical synthesis, most commonly through the methionine synthesis pathway, and the synthesized methionine is purified to obtain high-quality powder; Step 8: Cysteine ​​is usually prepared by fermentation or chemical synthesis, most commonly in the form of L-cysteine. The fermentation method uses a specific strain of bacteria for production, while chemical synthesis obtains cysteine ​​through a synthetic route. After purification by processes such as crystallization or membrane filtration, the final cysteine ​​powder is obtained; Step nine, then put the angelica extract powder, Platycladus orientalis leaf extract powder, vitamin B powder, vitamin H powder, zinc powder, selenium powder, methionine powder, cysteine ​​powder, niacin and folic acid prepared in steps one to eight into a mixing device for mixing, and finally form a feed additive.

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