An embryo transfer device for in vitro fertilization

By designing an automatically opened and closed fan-shaped piece sealing piece at the inner tube end of the embryo transfer, the problem of premature aspiration or respiration of embryos caused by pressure difference during embryo transfer is solved, and the success rate of transplantation is improved.

CN119837614BActive Publication Date: 2025-06-10AFFILIATED HOSPITAL OF INNER MONGOLIA MEDICAL UNIV (INNER MONGOLIA AUTONOMOUS REGION CARDIOVASCULAR INST)
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Patent Information

Application Number
CN202510322503.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-03-19
Publication Date
2025-06-10
Estimated Expiration
2045-03-19

AI Technical Summary

Technical Problem

When existing embryo transferring embryos to the uterus, it is easy for the embryo to be sucked out prematurely due to the pressure difference between the inside and outside of the uterus, or the embryo is respirated back into the inner tube after the injection is completed, resulting in the failure of embryo transfer.

Method used

An embryo transplanter is designed, and one end of the inner tube facing away from the syringe is equipped with a sealing piece that can be opened and closed. The sealing piece is made of multiple fan-shaped pieces. When the syringe inhales or discharges the embryo, the sealing piece is automatically opened and closed to prevent the embryo from being sucked out or back.

Benefits of technology

Through the automatic opening and closing function of the sealing sheet, the embryo is effectively prevented from being sucked out in advance or back into the inner tube during the transplantation process, which improves the success rate of embryo transfer.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to the technical field of surgical instruments, and particularly relates to an embryo transfer device for in vitro fertilization, which comprises a syringe, an inner tube and an outer tube. One end of the inner tube is connected to one end of the syringe, and the syringe is used to suck the embryo into the inner tube. The inner tube is inserted into the outer tube. A sealing piece capable of opening and closing is provided at the end of the inner tube facing away from the syringe. The sealing piece is formed by splicing a plurality of sector-shaped pieces. When the syringe sucks the embryo into the inner tube, the sealing piece swings open towards the syringe direction. When the syringe discharges the embryo from the inner tube, the sealing piece swings open towards the direction away from the syringe. The sealing piece is in a closed state during the process of the inner tube extending into the uterus to prevent the embryo from being discharged from the inner tube. After the embryo in the inner tube is discharged outside the inner tube, the sealing piece is in a closed state to prevent the embryo from being sucked back into the inner tube. The present invention solves the technical problems in the prior art that the embryo transfer device is prone to premature suction of the embryo and is prone to being sucked back after embryo injection.
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Description

Technical Field

[0001] The present invention relates to the technical field of surgical instruments, and in particular to an embryo transplanter for test-tube babies. Background Art

[0002] At present, the use of in vitro fertilization to breed test-tube babies is a relatively mature technology that can help families who cannot conceive naturally to have children. Test-tube babies are to take eggs and sperm outside the body for in vitro fertilization, and then after the early embryos are formed, the embryos are transplanted into the woman's uterus to breed into babies in the woman's uterus. When the embryo is transplanted into the woman's uterus, it is often necessary to use an embryo transplanter. The embryo transplanter includes a syringe, an inner tube and an outer tube. The inner tube is connected to the head of the syringe, and the outer tube is sleeved on the outside of the inner tube. When using the embryo transplanter, the embryo needs to be sucked into the inner tube first, and then the inner tube is extended into the woman's uterus, and the embryo in the inner tube is injected into the woman's uterus using a syringe.

[0003] When the existing embryo transplanter is inserted into the female uterus, it may be sucked out of the inner tube before reaching the designated position due to the pressure difference between the inside and outside of the uterus, thereby causing the embryo transplantation to fail. In addition, after the embryo injection is completed, it is easy for the embryo to be sucked back into the inner tube, which will also cause the embryo transplantation to fail. Summary of the invention

[0004] In order to overcome the deficiencies of the prior art, the present invention proposes an embryo transfer device for in vitro fertilization to solve the technical problems in the prior art that embryos are easily sucked out prematurely and easily sucked back after embryo injection.

[0005] The embryo transplanter for test tube babies of the present invention adopts the following technical solution:

[0006] An embryo transplanter for test-tube babies comprises a syringe, an inner tube and an outer tube, one end of the inner tube is connected to one end of the syringe, the syringe is used to suck the embryo into the inner tube, the inner tube is inserted into the outer tube, and the end of the inner tube away from the syringe is provided with a sealing piece that can be opened and closed, the sealing piece is formed by splicing a plurality of fan-shaped pieces, the sealing piece swings open toward the syringe when the syringe sucks the embryo into the inner tube, and swings open in a direction away from the syringe when the syringe discharges the embryo from the inner tube, the sealing piece is in a closed state during the process of the inner tube extending into the uterus to prevent the embryo from being discharged from the inner tube, and the sealing piece is in a closed state after the embryo in the inner tube is discharged from the inner tube to prevent the embryo from being sucked back into the inner tube.

[0007] Further, a response block is provided at one end of the inner tube facing away from the syringe. The response block is used to indicate the position where the inner tube extends into the uterus. The response block is a hollow tube, and the blocking piece is arranged inside the response block.

[0008] Further, an elastic ring is coaxially provided on the inner wall of one end of the response block. The cross-section of the elastic ring is corrugated. The blocking piece is arranged inside the elastic ring. The blocking piece is arranged on the response block through an elastic piece. The elastic ring includes a first corrugated section and a second corrugated section symmetrically arranged with respect to the blocking piece. The cross-sections of the first corrugated section and the second corrugated section are both arcs with convex surfaces facing the inside of the inner tube.

[0009] Further, a plurality of deformation holes are respectively and circumferentially spaced on the first corrugated section and the second corrugated section, so that the first corrugated section and the second corrugated section can elastically deform when the blocking piece swings open.

[0010] Further, the response block includes a first pipe section and a second pipe section. The outer diameters of the first pipe section and the second pipe section are the same. The inner diameter of the first pipe section is smaller than the inner diameter of the second pipe section. The elastic ring is arranged on the inner wall of the second pipe section. The inner diameter of the elastic ring is smaller than the inner diameter of the first pipe section.

[0011] Further, the elastic ring and the response block are made of the same material, both are metal materials.

[0012] Further, the response block is integrally injection-molded in the inner tube. The inner diameter of the inner tube is the same as the inner diameter of the first pipe section of the response block.

[0013] Further, a connecting sleeve is provided at one end of the outer tube close to the syringe. The connecting sleeve is used to connect with the endoscope component.

[0014] Further, a connecting boss is provided in the middle of the outer tube.

[0015] Further, one end of the inner tube away from the syringe extends out of the outer tube. The blocking piece is located at the part where the inner tube extends out of the outer tube.

[0016] The beneficial effects of the present invention are as follows: An embryo transfer device for in vitro fertilization of the present invention is provided with a sealing piece at one end of the inner tube away from the syringe. When using the syringe to suck the embryo into the inner tube, since the embryo is located in the nutrient solution, under the negative pressure of the syringe, the nutrient solution will flush open each sector piece of the sealing piece in the direction of the syringe, enabling the embryo to enter the inner tube; after the embryo is sucked into the inner tube, stop pulling the syringe, and the sealing piece resets under the action of its own elastic force, thereby sealing one end of the inner tube away from the syringe to prevent the embryo in the inner tube from being sucked out of the inner tube. When pushing the syringe to discharge the embryo from the inner tube, the nutrient solution pushes open each sector piece of the sealing piece in the direction away from the syringe, allowing the embryo to enter the uterus. After the embryo is discharged, stop pushing the syringe, and the sealing piece resets and seals the inner tube to prevent the embryo in the uterus from being sucked into the inner tube, thereby improving the success rate of embryo transfer.

[0017] Further, a response block and an elastic ring are provided in the inner tube, and the sealing piece is arranged in the elastic ring. The elastic ring can expand the opening angle of each sector piece of the sealing piece, and thus will not hinder the passage of the embryo. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings. Those skilled in the art should understand that these drawings are not necessarily drawn to scale.

[0019] Figure 1 A three-dimensional schematic diagram of an embodiment of an embryo transfer device for in vitro fertilization of the present invention;

[0020] Figure 2 An exploded view of an embodiment of an embryo transfer device for in vitro fertilization of the present invention;

[0021] Figure 3 A side view of an embodiment of an embryo transfer device for in vitro fertilization of the present invention;

[0022] Figure 4 For Figure 3 Cross-sectional view taken along line A-A in

[0023] Figure 5 For Figure 4 Enlarged view of the partial B in

[0024] Figure 6 For Figure 4 Another state schematic diagram of

[0025] Figure 7for Figure 6 Enlarged view of part C in the middle.

[0026] In the figure: 100, syringe; 200, inner tube; 201, joint; 210, response block; 211, elastic ring; 212, blocking piece; 213, sealing ring; 300, outer tube; 301, connecting boss; 303, connecting sleeve. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0028] An embodiment of an embryo transplanter for test tube babies of the present invention is as follows: Figures 1 to 7 As shown, the embryo transfer device for in vitro fertilization comprises a syringe 100, an inner tube 200 and an outer tube 300, one end of the inner tube 200 is connected with a joint 201, the inner tube 200 is connected to one end of the syringe 100 through the joint 201, and the syringe 100 is used to suck the embryo into the inner tube 200. The inner tube 200 is inserted into the outer tube 300, and the end of the outer tube 300 close to the syringe 100 is provided with a connecting sleeve 303, and the connecting sleeve 303 is used to connect with the endoscope component, and the middle part of the outer tube 300 is provided with a connecting protrusion 301. When in use, the inner tube 200 is first separated from the outer tube 300, and then the outer tube 300 is inserted into the vagina through an endoscope, so that the connecting boss 301 in the middle of the outer tube 300 passes through the cervical opening; then the embryo is sucked into the inner tube 200 using a syringe 100, and then the inner tube 200 is inserted into the outer tube 300, and the inner tube 200 enters the uterus through the outer tube 300. After reaching the appropriate depth, the syringe 100 is pushed to push the embryo in the inner tube 200 into the uterus.

[0029] In the present invention, the end of the inner tube 200 away from the syringe 100 is provided with a sealing piece 212 that can be opened and closed. The sealing piece 212 is a circular structure formed by a plurality of fan-shaped pieces. The sealing piece 212 is made of silicone. The sealing piece 212 is in a closed state when the inner tube 200 is inserted into the uterus to prevent the embryo from being discharged from the inner tube 200. Figure 5The state shown; after the embryo in the inner tube 200 is discharged outside the inner tube 200, the blocking piece 212 is in a closed state to prevent the embryo from being sucked back into the inner tube 200. Each fan-shaped piece can swing relatively, so that each fan-shaped piece of the blocking piece 212 swings towards the syringe 100 when the syringe 100 sucks the embryo into the inner tube 200, causing the blocking piece 212 to open. When the syringe 100 discharges the embryo from the inner tube 200, each fan-shaped piece of the blocking piece 212 swings away from the syringe 100, causing the blocking piece 212 to open. When using the syringe 100 to suck the embryo into the inner tube 200, since the embryo is located in the nutrient solution, under the negative pressure of the syringe 100, the nutrient solution will flush open each fan-shaped piece of the blocking piece 212 towards the syringe 100, enabling the embryo to enter the inner tube 200, as Figure 7 The state shown; after the embryo is sucked into the inner tube 200, stop pulling the syringe 100. The blocking piece 212 resets under the action of its own elastic force, and then blocks the end of the inner tube 200 away from the syringe 100 to prevent the embryo in the inner tube 200 from being sucked out of the inner tube 200. When pushing the syringe 100 to discharge the embryo from the inner tube 200, the nutrient solution pushes open each fan-shaped piece of the blocking piece 212 in the direction away from the syringe 100, enabling the embryo to enter the uterus. After the embryo is discharged, stop pushing the syringe 100, and the blocking piece 212 resets and blocks the inner tube 200 to prevent the embryo in the uterus from being sucked into the inner tube 200.

[0030] In this embodiment, a response block 210 is provided at one end of the inner tube 200 away from the syringe 100. The response block 210 is used to prompt the position where the inner tube 200 extends into the uterus, which can facilitate the doctor to judge the position where the inner tube 200 extends into the uterus. The response block 210 is a hollow tube, and the blocking piece 212 is arranged inside the response block 210. In this embodiment, an elastic ring 211 is coaxially provided on the inner wall at one end of the response block 210. The cross-section of the elastic ring 211 is corrugated. The blocking piece 212 is arranged inside the elastic ring 211, and the blocking piece 212 is arranged on the response block 210 through an elastic piece. The elastic ring 211 includes a first corrugated section and a second corrugated section symmetrically arranged with respect to the blocking piece 212. The first corrugated section is located on the side of the second corrugated section close to the syringe 100. The cross-sections of the first corrugated section and the second corrugated section are both arcs with the convex surface facing the inside of the inner tube 200. A plurality of deformation holes are respectively and circumferentially spaced on the first corrugated section and the second corrugated section, so that the first corrugated section and the second corrugated section can elastically deform when the blocking piece 212 swings open.

[0031] In the present invention, each sector piece of the blocking piece 212 is respectively fixed on the inner wall of the elastic ring 211, and the blocking piece 212 is located at the connection position between the first corrugated section and the second corrugated section. In this way, when each sector piece of the blocking piece 212 swings respectively, the first corrugated section and the second corrugated section will respectively deform. Compared with the way of directly connecting the blocking piece 212 to the inner wall of the inner tube 200, in this embodiment, the swinging angle of each sector piece can be enlarged, and the opening degree of the blocking piece 212 can be made larger, so as to reduce the obstruction to the embryo. In this embodiment, the elastic ring 211 and the response block 210 are made of the same material, both of which are metal materials. By setting the elastic ring 211 as a metal material, the blocking piece 212 can be quickly reset. A sealing ring 213 is provided between the outer side of the elastic ring 211 and the inner wall of the inner tube 200, so as to prevent the nutrient solution from passing through the deformation holes of the first corrugated section and the second corrugated section from the periphery of the elastic ring 211.

[0032] In this embodiment, the response block 210 includes a first pipe section and a second pipe section integrally arranged. The outer diameters of the first pipe section and the second pipe section are the same, and the inner diameter of the first pipe section is smaller than the inner diameter of the second pipe section. The elastic ring 211 is arranged on the inner wall of the second pipe section, and the inner diameter of the elastic ring 211 is smaller than the inner diameter of the first pipe section. The response block 210 is integrally injection-molded in the inner tube 200, and the inner diameter of the inner tube 200 is the same as the inner diameter of the first pipe section of the response block 210. One end of the inner tube 200 far away from the syringe 100 extends out of the outer tube 300, and the blocking piece 212 is located at the part of the inner tube 200 extending out of the outer tube 300.

[0033] The using process of an embryo transfer device for in vitro fertilization of the present invention: First, use an endoscope to observe the cervical orifice, then use a disinfected cotton swab to clean and disinfect the mucus, and then insert the outer tube 300 into the vagina through the endoscope, so that the connecting convex head 301 in the middle of the outer tube 300 passes through the cervical orifice and stops inside the uterus. Then use the syringe 100 to suck the embryo into the inner tube 200. Since the embryo is in the nutrient solution, the nutrient solution will be sucked into the inner tube 200 together when sucking the embryo. When sucking the embryo and the nutrient solution, each sector piece of the blocking piece 212 will swing towards the syringe 100 under the impact of the nutrient solution, and the first corrugated section of the elastic ring 211 will be sunken, so that each sector piece of the blocking piece 212 is completely opened, as Figure 7 shown in the state, so that the embryo can smoothly enter the inner tube 200. After the embryo is sucked in, the elastic ring 211 and the blocking piece 212 are reset, and the blocking piece 212 blocks the inner tube 200, as Figure 5 shown in the state, to prevent the embryo from being sucked out of the inner tube 200 in advance due to the pressure difference inside and outside the uterine cavity during the process of inserting the inner tube 200 into the uterus.

[0034] When the inner tube 200 is inserted into the uterus through the outer tube 300 and reaches the appropriate depth, the syringe 100 is pushed to inject the embryo in the inner tube 200 into the uterus. During the injection, the blocking piece 212 swings under the pushing force of the culture solution, and the second corrugated section of the elastic ring 211 is recessed, so that each sector piece of the blocking piece 212 swings open along the direction of the nutrient solution flowing out. After the injection is completed, the elastic ring 211 and the blocking piece 212 are reset, and the blocking piece 212 blocks the inner tube 200 to prevent the nutrient solution and the embryo from being sucked back into the inner tube 200, thereby improving the transplantation success rate. Finally, the inner tube 200 and the outer tube 300 are removed from the uterus together, and the embryo transplantation is completed.

[0035] The above are only the preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. An embryo transplanter for in vitro fertilization, comprising a syringe (100), an inner tube (200) and an outer tube (300), wherein one end of the inner tube (200) is connected to one end of the syringe (100), the syringe (100) is used to suck the embryo into the inner tube (200), and the inner tube (200) is inserted into the outer tube (300), characterized in that: An end of the inner tube (200) facing away from the syringe (100) is provided with a sealing piece (212) that can be opened and closed. The sealing piece (212) is formed by a plurality of fan-shaped pieces being joined together. When the syringe (100) sucks the embryo into the inner tube (200), the sealing piece (212) swings open in the direction of the syringe (100). When the syringe (100) discharges the embryo from the inner tube (200), the sealing piece (212) swings open in the direction away from the syringe (100). When the inner tube (200) is extended into the uterus, the sealing piece (212) is in a closed state to prevent the embryo from being discharged from the inner tube (200). After the embryo in the inner tube (200) is discharged from the inner tube (200), the sealing piece (212) is in a closed state to prevent the embryo from being sucked back into the inner tube (200). A response block (210) is provided at one end away from the syringe (100), and the response block (210) is used to indicate the position of the inner tube (200) extending into the uterus. The response block (210) is in the shape of a hollow tube. The blocking piece (212) is arranged inside the response block (210). An elastic ring (211) is coaxially provided on the inner wall of one end of the response block (210). The cross section of the elastic ring (211) is corrugated. The blocking piece (212) is arranged inside the elastic ring (211). The blocking piece (212) is arranged on the response block (210) through the elastic piece. The elastic ring (211) comprises a first corrugated section and a second corrugated section which are symmetrically arranged with respect to the blocking piece (212). The cross sections of the first corrugated section and the second corrugated section are both arc-shaped with the convex surface facing the inside of the inner tube (200).

2. The embryo transplanter for test tube baby according to claim 1, characterized in that: A plurality of deformation holes are respectively provided at intervals in the circumferential direction of the first corrugated section and the second corrugated section, so that the first corrugated section and the second corrugated section can be elastically deformed when the blocking piece (212) is swung open.

3. The embryo transplanter for test tube baby according to claim 2, characterized in that: The response block (210) comprises a first pipe section and a second pipe section, the first pipe section and the second pipe section have the same outer diameter, the inner diameter of the first pipe section is smaller than the inner diameter of the second pipe section, the elastic ring (211) is arranged on the inner wall of the second pipe section, and the inner diameter of the elastic ring (211) is smaller than the inner diameter of the first pipe section.

4. The embryo transplanter for test tube baby according to claim 3, characterized in that: The elastic ring (211) and the response block (210) are made of the same material, which is metal.

5. The embryo transplanter for test tube baby according to claim 4, characterized in that: The response block (210) is integrally injection-molded in the inner tube (200), and the inner diameter of the inner tube (200) is the same as the inner diameter of the first tube section of the response block (210).

6. The embryo transplanter for in vitro fertilization according to any one of claims 1 to 5, characterized in that: A connecting sleeve (303) is provided at one end of the outer tube (300) close to the syringe (100), and the connecting sleeve (303) is used to connect to an endoscope component.

7. The embryo transplanter for test tube baby according to claim 6, characterized in that: A connecting protrusion (301) is provided in the middle of the outer tube (300).

8. The embryo transplanter for test tube baby according to claim 7, characterized in that: One end of the inner tube (200) away from the syringe (100) extends out of the outer tube (300), and the blocking piece (212) is located at the portion of the inner tube (200) that extends out of the outer tube (300).

Citation Information

Patent Citations

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    CN209301262U