Nutrient solution containing yak penis extracting solution and capable of improving bone mineral density

Abstract

The invention relates to a yak penis extracting solution-containing nutrient solution capable of improving bone mineral density, and also discloses a production process of the nutrient solution, and the production process comprises the following steps: (1) preparing a concentrated yak penis extracting solution; (2) preparing auxiliary liquid; and (3) mixing the prepared concentrated yak penis extracting solution with an auxiliary solution according to a volume ratio of 1: (0.2-0.5), and carrying out conventional sterilization treatment on the mixed solution to obtain a nutrient solution finished product. The nutrient solution contains all essence components of yak penis, and particularly, high-quality testosterone rich in the nutrient solution can promote proliferation and differentiation of bone cells and can directly act on receptors on the surfaces of the bone cells to promote proliferation and maturation of the bone cells, so that the bone mass is increased, and the bone density is improved; the auxiliary liquid beneficial component in the nutrient solution also has the effects of warming and tonifying kidney essence and tonifying and strengthening bones, and can supplement the testosterone component in the yak penis extracting solution, so that the nutrient solution has obvious bone tonifying and strengthening effects on osteoporosis patients.

Description

Technical Field

[0001] The invention relates to a nutrient solution containing yak whip extract and capable of improving bone density. Background Art

[0002] Yaks are the treasure of the plateau. In the long process of biological evolution, they coexist with the harsh natural environment of the snowy plateau. Yak whip was first recorded in "Ming Yi Bie Lu". Tibetan medicine calls it "Zhong", also known as ox kidney. Yak whip is rich in protein, testosterone, natural steroid hormones, vitamins A and C, and inorganic calcium, phosphorus, and iron. It is a superior treasure for people to nourish the kidney and improve kidney function. The essence of yak whip has a good tonic and conditioning effect not only on the human kidney, but also on the whole human body. Studies have shown that testosterone can promote the proliferation and differentiation of bone cells, while reducing bone absorption and maintaining bone health and stability; testosterone can promote the proliferation and maturation of bone cells by directly acting on the receptors on the surface of bone cells, thereby increasing bone mass. In addition, testosterone can also increase bone density and bone strength by promoting calcium absorption and reducing calcium loss to bones.

[0003] The purpose of the present invention is to efficiently extract effective ingredients from yak whip and add some beneficial ingredients to prepare a nutrient solution that can improve bone density. Summary of the invention

[0004] The technical problem to be solved by the present invention is to provide a nutrient solution containing yak whip extract which can improve bone density, mainly bringing good news to middle-aged and elderly patients with osteoporosis.

[0005] The technical solution adopted by the present invention to solve the technical problem is: a production process of a nutrient solution containing yak whip extract that can improve bone density, comprising the following steps:

[0006] (1) preparing yak whip concentrated extract;

[0007] (2) preparing auxiliary liquid;

[0008] (3) mixing the prepared yak whip concentrated extract with the auxiliary liquid in a volume ratio of 1:(0.2-0.5), performing conventional sterilization on the mixed liquid to obtain a finished nutrient solution, and quantitatively packaging the finished nutrient solution under aseptic conditions to facilitate packaging, sales and use;

[0009] The preparation of the concentrated yak whip extract comprises the following steps:

[0010] a. After removing the skin, fat membrane and urethra of the yak whip, soak and clean the yak whip for more than 30 minutes to remove impurities on the surface;

[0011] b. Cut the cleaned yak whip into sections and put them into a dryer for drying at a drying temperature set at 45°C;

[0012] c. The dried yak whip segments are cut into thin slices and then placed in a clean container, an appropriate amount of purified water is added, cellulase and protease are added for enzymatic hydrolysis, the temperature of the enzymatic hydrolysis reaction is controlled at 50°C ± 5°C, the reaction time is 3.5h ± 0.5h, and a yak whip hydrolyzate is obtained;

[0013] d. The yak whip enzymatic hydrolyzate was transferred to a high-pressure extraction device and treated with a pressure of 25MPa±5Mpa for 20min±5min to obtain a yak whip extract with a high extraction rate;

[0014] e. The obtained yak whip extract was filtered and then concentrated using a thin film evaporator, and the temperature was controlled at 50°C ± 5°C during the treatment process to obtain a concentrated yak whip extract;

[0015] Wherein, preparing auxiliary liquid comprises the following steps:

[0016] Ⅰ. Mix the following materials by weight: 1.5 parts of Eucommia ulmoides, 1.5 parts of Epimedium, 1.5 parts of Rehmannia root, 1.5 parts of Dioscorea opposita, 1.5 parts of Cornus officinalis, 1.5 parts of Lycium barbarum, 1.5 parts of Drynaria fortunei, 3 parts of Salvia miltiorrhiza, 1.5 parts of Red Peony Root, 1 part of Peach Kernel, 1 part of Angelica sinensis, and 1 part of Chuanxiong, add water and boil into a soup;

[0017] Ⅱ. After filtering the boiled soup, use a thin film evaporator to concentrate it to obtain a concentrated soup, which is the auxiliary liquid.

[0018] A nutrient solution containing yak whip extract and capable of improving bone density is prepared by adopting the above production process.

[0019] The beneficial effects of the present invention are as follows: the nutrient solution of the present invention contains all the essence components of yak whip, especially the high-quality testosterone rich therein can promote the proliferation and differentiation of bone cells, and can directly act on the receptors on the surface of bone cells to promote the proliferation and maturation of bone cells, thereby increasing bone mass and improving bone density; at the same time, testosterone can also improve bone density and bone strength by promoting calcium absorption and reducing calcium loss in bones; the auxiliary liquid beneficial components in the nutrient solution of the present invention themselves also have the effects of warming and nourishing kidney essence, nourishing and strengthening bones, and can complement the testosterone components in the yak whip extract, and have significant effects of nourishing kidney essence, nourishing and strengthening bones, and improving bone density, especially for middle-aged and elderly patients with osteoporosis. DETAILED DESCRIPTION

[0020] The present invention is further described below by means of several embodiments and comparative examples. The described embodiments are only partial embodiments of the present invention, rather than all embodiments.

[0021] Example 1

[0022] A nutrient solution containing yak whip extract and capable of improving bone density is prepared by the following production process:

[0023] (1) preparing yak whip concentrated extract;

[0024] (2) preparing auxiliary liquid;

[0025] (3) mixing the prepared yak whip concentrated extract with the auxiliary liquid in a volume ratio of 1:0.2, performing conventional sterilization on the mixed liquid to obtain a finished nutrient solution, and quantitatively packaging the finished nutrient solution under aseptic conditions to facilitate packaging, sales and use;

[0026] The preparation of the concentrated yak whip extract comprises the following steps:

[0027] a. After removing the skin, fat membrane and urethra of the yak whip, soak and clean the yak whip for more than 30 minutes to remove impurities on the surface;

[0028] b. Cut the cleaned yak whip into sections and put them into a dryer for drying at a drying temperature set at 45°C;

[0029] c. The dried yak whip segments are cut into thin slices and then placed in a clean container, an appropriate amount of purified water is added, cellulase and protease are added for enzymatic hydrolysis, the temperature of the enzymatic hydrolysis reaction is controlled at 50°C ± 5°C, the reaction time is 3.5h ± 0.5h, and a yak whip hydrolyzate is obtained;

[0030] d. The yak whip enzymatic hydrolyzate was transferred to a high-pressure extraction device and treated with a pressure of 25MPa±5Mpa for 20min±5min to obtain a yak whip extract with a high extraction rate;

[0031] e. The obtained yak whip extract was filtered and then concentrated using a thin film evaporator, and the temperature was controlled at 50°C ± 5°C during the treatment process to obtain a concentrated yak whip extract;

[0032] Wherein, preparing auxiliary liquid comprises the following steps:

[0033] Ⅰ. Mix the following materials by weight: 1.5 parts of Eucommia ulmoides, 1.5 parts of Epimedium, 1.5 parts of Rehmannia root, 1.5 parts of Dioscorea opposita, 1.5 parts of Cornus officinalis, 1.5 parts of Lycium barbarum, 1.5 parts of Drynaria fortunei, 3 parts of Salvia miltiorrhiza, 1.5 parts of Red Peony Root, 1 part of Peach Kernel, 1 part of Angelica sinensis, and 1 part of Chuanxiong, add water and boil into a soup;

[0034] Ⅱ. After filtering the boiled soup, use a thin film evaporator to concentrate it to obtain a concentrated soup, which is the auxiliary liquid.

[0035] Example 2

[0036] The difference between Example 2 and Example 1 is that the volume ratio of the yak whip concentrated extract and the auxiliary liquid when mixed in step (3) is different, and the volume ratio of the two is 1:0.3.

[0037] Example 3

[0038] The difference between Example 3 and Example 1 is that the volume ratio of the yak whip concentrated extract and the auxiliary liquid when mixed in step (3) is different, and the volume ratio of the two is 1:0.5.

[0039] Comparative Example 1

[0040] The difference between Comparative Example 1 and Example 2 is that the concentrated yak whip extract prepared in Example 2 is directly used as the finished liquid without the auxiliary liquid prepared in Example 2.

[0041] Comparative Example 2

[0042] The difference between Comparative Example 2 and Example 2 is that the auxiliary liquid prepared in Example 2 is directly used as the finished liquid without containing the yak whip concentrated extract prepared in Example 2.

[0043] The liquid preparations prepared in Example 2, Comparative Example 1 and Comparative Example 2 were tested for clinical effects:

[0044] 150 osteoporosis cases were recruited. The patients were aged between 55 and 85 years old and were equally divided into three groups: A, B, and C. Their bone density values ​​were tested and recorded.

[0045] Simultaneous administration test (single dose is the same):

[0046] Patients in group A took the nutrient solution prepared in Example 2 once a day for 15 consecutive days;

[0047] Patients in group B took the liquid prepared in comparative example 1 once a day for 15 consecutive days;

[0048] Patients in Group C took the liquid prepared in Comparative Example 2 once a day for 15 consecutive days.

[0049] After 15 days, the patient's bone density was tested again and recorded, and it was found that:

[0050] Among the patients in Group A, 47 cases had a significant increase in bone density, and the patients were in good spirits, light-bodied and full of energy. The bone density of 3 cases increased slightly but not significantly.

[0051] Among the patients in group B, 35 had a significant increase in bone density, while the other 15 had a smaller increase in bone density.

[0052] Among the patients in group C, 25 had a significant increase in bone density, while the other 25 had a smaller increase in bone density.

[0053] It can be seen that the nutrient solution prepared in Example 2 has the best and significant effect on improving the bone density of osteoporosis patients, that is, the therapeutic efficacy of the yak whip concentrated extract and the auxiliary liquid mixed in proportion is the best, and the yak whip concentrated extract plays a key and main role.

[0054] The main functions of the components in the auxiliary liquid of the present invention are as follows:

[0055] Eucommia ulmoides and Epimedium: warm and nourish kidney essence, strengthen tendons and bones, eliminate rheumatism, and resist aging;

[0056] Rehmannia root, Chinese yam, cornus officinalis, wolfberry: nourish the liver and kidney, replenish essence and marrow;

[0057] Drynaria, Salvia miltiorrhiza, Red Peony Root, Peach Kernel, Angelica Sinensis, Ligusticum chuanxiong: promote blood circulation, dredge meridians, and set bones.

[0058] The above embodiments are only used to explain the present invention, rather than to limit the protection of the rights of the present invention. Any non-substantial changes made on the basis of the essential scheme of the present invention shall fall within the protection scope of the present invention.

Claims

1. A production process of a nutrient solution containing yak whip extract for improving bone density, characterized in that The following steps are involved: (1) preparing yak whip concentrated extract; (2) preparing auxiliary liquid; (3) mixing the prepared yak whip concentrated extract with the auxiliary liquid in a volume ratio of 1:(0.2-0.5), performing conventional sterilization on the mixed liquid to obtain a finished nutrient solution, and quantitatively packaging the finished nutrient solution under aseptic conditions to facilitate packaging, sales and use; The preparation of the concentrated yak whip extract comprises the following steps: a. After removing the skin, fat membrane and urethra of the yak whip, soak and clean the yak whip for more than 30 minutes to remove impurities on the surface; b. Cut the cleaned yak whip into sections and put them into a dryer for drying at a drying temperature set at 45°C; c. The dried yak whip segments are cut into thin slices and then placed in a clean container, an appropriate amount of purified water is added, cellulase and protease are added for enzymatic hydrolysis, the temperature of the enzymatic hydrolysis reaction is controlled at 50°C ± 5°C, the reaction time is 3.5h ± 0.5h, and a yak whip hydrolyzate is obtained; d. The yak whip enzymatic hydrolyzate was transferred to a high-pressure extraction device and treated with a pressure of 25MPa±5Mpa for 20min±5min to obtain a yak whip extract with a high extraction rate; e. The obtained yak whip extract was filtered and then concentrated using a thin film evaporator, and the temperature was controlled at 50°C ± 5°C during the treatment process to obtain a concentrated yak whip extract; Wherein, preparing auxiliary liquid comprises the following steps: Ⅰ. Mix the following materials by weight: 1.5 parts of Eucommia ulmoides, 1.5 parts of Epimedium, 1.5 parts of Rehmannia root, 1.5 parts of Dioscorea opposita, 1.5 parts of Cornus officinalis, 1.5 parts of Lycium barbarum, 1.5 parts of Drynaria fortunei, 3 parts of Salvia miltiorrhiza, 1.5 parts of Red Peony Root, 1 part of Peach Kernel, 1 part of Angelica sinensis, and 1 part of Chuanxiong, add water and boil into a soup; Ⅱ. After filtering the boiled soup, use a thin film evaporator to concentrate it to obtain a concentrated soup, which is the auxiliary liquid.

2. A nutrient solution containing yak whip extract for improving bone density, characterized in that: The method is prepared by the production process as claimed in claim 1.