Chemical buffering agent for preventing or treating bovine rumen acidosis and application thereof

Abstract

The invention is suitable for the technical field of cattle breeding, and provides a chemical buffering agent for preventing or treating cattle rumen acidosis and application thereof. According to the invention, the chemical buffering agent consisting of soda, calcium oxide, magnesium oxide, light calcium carbonate, yeast and vitamin B1 in a reasonable ratio is added into the basic ration of the dairy cattle or beef cattle, and the chemical buffering agent can effectively neutralize acid in rumen, reduce corrosion to the rumen and protect gastric mucosa, so that the acidosis of the rumen of the cattle is treated and prevented; the excessive production of lactic acid is fundamentally prevented. The method reduces the occurrence rate of rumen acidosis while maintaining the milk yield of dairy cows or beef cattle, is green and efficient, is simple and convenient to use, is low in cost, does not bring extra labor or cost burden to a pasture, and also can remarkably improve the production benefit of a large-scale farm. The chemical buffering agent has the characteristics of no toxicity, no residue, good biocompatibility, easiness in degradation and the like, reduces toxic and side effects and drug resistance risks, and ensures long-term health of cattle.

Description

Technical Field

[0001] The invention belongs to the technical field of cattle breeding, and in particular relates to a chemical buffer for preventing or treating cattle rumen acidosis and application thereof. Background Art

[0002] In the field of cattle (including dairy cows and beef cattle), facing the severe challenges of disease prevention and control and the need for cost control, the industry is transforming towards scale and intensiveness. The rumen is the main place for ruminants to digest and metabolize nutrients, and its health is directly related to the body health and production performance of the animal. Bovine rumen acidosis is a common nutritional metabolic disease. Due to the excessive intake of carbohydrate-rich concentrate feed by cattle, lactic acid accumulates in the rumen, causing the pH value of rumen fluid to decrease, triggering a series of physiological and metabolic abnormalities, including imbalance of rumen microbial community, nutrient absorption disorder and immune response disorder of the body. The disease can cause a decrease in feed digestibility, corrode the papillary structure of the rumen epithelium, affect the normal absorption function of the rumen for nutrients, and easily induce diseases such as mastitis and laminitis. Rumen acidosis is mainly divided into subacute rumen acidosis and acute rumen acidosis. The pH of subacute rumen acidosis is 5.2-5.8, which is more common in dairy and beef cattle farming. The main manifestations are decreased feed intake and milk production, as well as digestive tract symptoms such as depression and diarrhea. The pH value of acute rumen acidosis is less than 5, which is easy to cause systemic inflammation such as bacteremia, and the mortality rate is high. Improper feeding management, especially the excessive intake of high-concentrate feed, is the main cause of rumen acidosis. The high-concentrate and low-roughage feeding method does not match the digestive physiological characteristics of cattle, making it difficult for cattle to adapt and cause metabolic diseases. When changing feed, there is a lack of sufficient transition period, especially when converting from high-proportion roughage to high-proportion concentrate feed, the microorganisms of the dominant population in the rumen cannot adapt to and digest the new feed in a short time, thus causing disease. Rumen acidosis caused by high-concentrate feed intake may occur in any season of the year, seriously affecting the production performance of cattle, resulting in a decrease in beef production and milk production, causing serious economic losses to farmers, and hindering the healthy development of the entire cattle industry.

[0003] The current technology for alleviating rumen acidosis in cattle has the following main disadvantages: (1) The treatment process is cumbersome and time-consuming: Gastric lavage therapy, as one of the common methods, uses a stomach tube to inject 1-3% sodium bicarbonate or 5% magnesium oxide to repeatedly flush the rumen and discharge the contents in the rumen; this method is complicated to operate, consumes a lot of manpower and time, and is difficult to achieve long-term prevention and treatment effects. In addition, rumen cut-open surgery is also used to treat the disease, but its operation is time-consuming, and the postoperative recovery effect is difficult to guarantee, which can easily cause a variety of complications and bring serious economic losses to farmers. (2) High treatment cost and poor effect: Although drug treatment is commonly used, it is costly, and the selection of drug types and doses is extremely challenging. If the dose is too small, the treatment effect is poor, and if it is too large, the sick cow may die during the infusion process. At the same time, there is also the risk of unreasonable drug selection and incompatibility. (3) Side effects and usage restrictions of drug additives: Some drug additives are used to treat rumen acidosis in cattle, but these drug additives may have toxic side effects and drug resistance problems. Long-term use may have adverse effects on the health of cattle and the quality of dairy products. More importantly, the current treatment method only focuses on systemic treatment after lactic acid absorption, ignoring the fundamental prevention of further production and absorption of lactic acid, resulting in repeated illness, a vicious cycle, and failure to effectively protect the gastric mucosa. In order to overcome these shortcomings and promote the sustainable development of the cattle industry, it is necessary to continuously explore and innovate safer, more effective and economical technical means. To this end, the present invention proposes a chemical buffer for preventing or treating bovine rumen acidosis and its application. Summary of the invention

[0004] The purpose of the present invention is to provide a chemical buffer for preventing or treating bovine rumen acidosis and its application, aiming to solve the problems raised in the above background technology.

[0005] The purpose of the present invention is achieved through the following technical solutions: A chemical buffer for preventing or treating rumen acidosis in cattle comprises the following raw materials in percentage by mass: 10% soda, 15% calcium oxide, 15% magnesium oxide, 10% light calcium carbonate, 49.98% yeast and 0.02% vitamin B1.

[0006] A use of the chemical buffer described above in preparing feed for preventing or treating rumen acidosis in cattle.

[0007] Furthermore, the feed includes a chemical buffer and a basal diet.

[0008] Furthermore, the cattle include dairy cows and beef cattle.

[0009] Furthermore, the basic daily diet for dairy cows includes the following raw materials in percentage by mass: 28% corn, 4.2% corn germ meal, 13.9% soybean meal, 5.5% corn DDGS, 0.5% cane molasses, 0.3% expanded urea 200 type, 0.5% stone powder, 0.3% salt, 0.3% dairy cow premix, 31% silage, 3.9% whole cottonseed and 11.6% alfalfa.

[0010] Furthermore, the basic diet for beef cattle includes the following raw materials in percentage by mass: 50% corn, 11% soybean meal, 4% soybean hulls, 14% corn germ meal, 15% corn DDGS, 2% cane molasses, 0.7% expanded urea 200, 2% stone powder, 0.8% sodium chloride and 0.5% beef cattle premix.

[0011] A method for preventing or treating rumen acidosis in dairy cows comprises feeding a feed comprising a basic diet and 20 g of a chemical buffer every day to prevent rumen acidosis in lactating dairy cows; and feeding a feed comprising a basic diet and 40 g of a chemical buffer every day to treat rumen acidosis in dairy cows.

[0012] A method for preventing or treating rumen acidosis in beef cattle comprises feeding a feed comprising a basic diet and 20 g of a chemical buffer every day to prevent rumen acidosis in fattening beef cattle; and feeding a feed comprising a basic diet and 60 g of a chemical buffer every day to treat rumen acidosis in beef cattle.

[0013] Compared with the prior art, the present invention has the following beneficial effects: 1. The present invention adds a chemical buffer composed of soda, calcium oxide, magnesium oxide, light calcium carbonate, yeast and vitamin B1 in a reasonable ratio to the basic diet of dairy cows or beef cattle. This chemical buffer can effectively neutralize the acid in the rumen, reduce the corrosion of the rumen, and protect the gastric mucosa, thereby treating and preventing rumen acidosis in cattle, and fundamentally preventing the excessive production of lactic acid. While maintaining the milk production of dairy cows or beef cattle, this method reduces the incidence of rumen acidosis. It is not only green and efficient, but also simple to use and low-cost, and does not bring additional labor or cost burden to the ranch, and can also significantly improve the production efficiency of large-scale farms.

[0014] 2. The chemical buffer used in the present invention is safer and non-toxic, has better biocompatibility and better degradation performance than traditional drug additives, and can replace traditional drug additives, reducing the risk of toxic side effects and drug resistance. By directly neutralizing the acid in the rumen and promoting rumen peristalsis, the formula effectively protects the gastric mucosa from acid corrosion, greatly reducing the potential threat to cattle health and ensuring the long-term health of cattle. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 Schematic diagram of the experimental scheme of the present invention. DETAILED DESCRIPTION

[0016] In order to have a clearer understanding of the technical features, purposes and beneficial effects of the present invention, the technical solution of the present invention is now described in detail below, but it should not be construed as limiting the applicable scope of the present invention.

[0017] The specific implementation of the present invention is described in detail below in conjunction with specific embodiments.

[0018] To examine the effects of feeding chemical buffers on the prevention and treatment of ruminal acidosis in cattle ( Figure 1 ), add a reasonable proportion of chemical buffers (Table 3) to the basic diet formula of lactating dairy cows and fattening beef cattle (Table 1 and Table 2) and feed them to cows in a quantitative manner (3 times / day).

[0019]

[0020]

[0021]

[0022] Example 1: According to clinical symptoms and rumen fluid pH value, 58 dairy cows with rumen acidosis were selected and divided into 2 groups: 50 cows in the feeding group (divided into 3 groups, 19 cows in feeding group 1, 16 cows in feeding group 2, and 15 cows in feeding group 3), and feeding groups 1 to 3 were fed with basal diet + 30g chemical buffer, basal diet + 40g chemical buffer, and basal diet + 50g chemical buffer every day; 8 cows in the control group were fed with basal diet every day. After 10 days of feeding, the degree of relief of rumen acidosis symptoms of dairy cows was observed every 3 days. The results are shown in Table 4:

[0023] Note: Clinical symptoms (including body temperature, pulse, mental state, stool status, rumination status and dehydration degree) are judged according to the comprehensive score, with 5 points for healthy state and 1 point for acidosis state.

[0024] The results showed that starting from the sixth day of feeding, the symptoms of rumen acidosis in dairy cows were significantly relieved, the rumen pH value basically returned to the normal range, and the clinical symptoms were basically recovered. After the experiment, all dairy cows recovered. Considering the effect and cost comprehensively, adding 40g of chemical buffer to the basic diet every day for feeding has the best effect on treating rumen acidosis in beef cattle.

[0025] Example 2: According to clinical symptoms and rumen pH value, 73 beef cattle with rumen acidosis were selected and divided into 2 groups: 60 cattle in the feeding group (divided into 3 groups, 20 cattle in each feeding group 1-3), feeding groups 1-3 were fed with basal diet + 40g chemical buffer, basal diet + 50g chemical buffer, and basal diet + 60g chemical buffer every day; 13 cattle in the control group were fed with basal diet every day. After 10 days of feeding, the degree of relief of rumen acidosis symptoms of beef cattle was observed every 3 days. The results are shown in Table 5:

[0026] Note: Clinical symptoms (including body temperature, pulse, mental state, stool status, rumination status and dehydration degree) are judged according to the comprehensive score, with 5 points for healthy state and 1 point for acidosis state.

[0027] The results showed that starting from the sixth day of feeding, the symptoms of rumen acidosis in beef cattle were significantly relieved, the rumen pH value basically returned to the normal range, and the clinical symptoms were basically recovered. After the experiment, all beef cattle recovered. Considering the effect and cost comprehensively, adding 60g of chemical buffer to the basic diet every day for feeding has the best effect on treating rumen acidosis in beef cattle.

[0028] Example 3: 96 healthy lactating cows were divided into 2 groups: 70 cows in the feeding group (divided into 3 groups, 17 cows in feeding group 1, 17 cows in feeding group 2, and 23 cows in feeding group 3), feeding groups 1 to 3 were fed with basal diet + 10g chemical buffer, basal diet + 20g chemical buffer, and basal diet + 30g chemical buffer every day; 13 cows in the control group were fed with basal diet every day. After two months of feeding, the proportion of acidosis was observed every 15 days. The results are shown in Table 6:

[0029] Note: A rumen fluid pH value below 5.8 is taken as an indicator of acidosis.

[0030] The results showed that after the experiment, the proportion of rumen acidosis in the feeding group was significantly lower than that in the control group. This shows that chemical buffers can significantly prevent rumen acidosis in lactating dairy cows. Considering the effect and cost comprehensively, adding 20g of chemical buffers to the basic diet every day for feeding has the best effect in preventing rumen acidosis in lactating dairy cows.

[0031] Example 4: 80 healthy fattening cattle were divided into 2 groups: 59 cattle in the feeding group (divided into 3 groups, 19 cattle in feeding group 1, 18 cattle in feeding group 2, and 22 cattle in feeding group 3), feeding groups 1 to 3 were fed with basal diet + 10g chemical buffer, basal diet + 20g chemical buffer, and basal diet + 30g chemical buffer every day; 21 cattle in the control group were fed with basal diet every day. After two months of feeding, the proportion of acidosis was observed every 15 days. The results are shown in Table 7:

[0032] Note: A rumen fluid pH value below 5.8 is taken as an indicator of acidosis.

[0033] The results showed that after the experiment, the proportion of rumen acidosis in the feeding group was significantly lower than that in the control group. This shows that chemical buffers can significantly prevent rumen acidosis in fattening beef cattle. Considering the effect and cost, adding 20g of chemical buffers to the basic diet every day for feeding has the best effect in preventing rumen acidosis in fattening beef cattle.

[0034] In summary, for dairy cows with rumen acidosis, adding 40g of chemical buffer to their basal diet every day; for beef cattle with rumen acidosis, adding 60g of chemical buffer to their basal diet every day can significantly alleviate their rumen acidosis symptoms. At the same time, in the normal feeding process of dairy cows and beef cattle, adding 20g of chemical buffer to the basal diet every day can effectively prevent the occurrence of rumen acidosis. This method is worth promoting and applying in farms.

[0035] The above are only preferred embodiments of the present invention. It should be pointed out that, for those skilled in the art, several modifications and improvements can be made without departing from the concept of the present invention. These should also be regarded as the protection scope of the present invention. These will not affect the effect of the implementation of the present invention and the practicality of the patent.

Claims

1. A chemical buffer for preventing or treating rumen acidosis in cattle, characterized in that: The raw materials include, by mass percentage, 10% soda, 15% calcium oxide, 15% magnesium oxide, 10% light calcium carbonate, 49.98% yeast and 0.02% vitamin B1.

2. Use of the chemical buffer according to claim 1 in preparing feed for preventing or treating rumen acidosis in cattle.

3. The use according to claim 2, characterized in that: The feed includes a chemical buffer and a basal diet.

4. The use according to claim 3, characterized in that: The cattle include dairy cows and beef cattle.

5. The use according to claim 4, characterized in that: The basic daily diet of the dairy cow includes the following raw materials in percentage by mass: 28% corn, 4.2% corn germ meal, 13.9% soybean meal, 5.5% corn DDGS, 0.5% cane molasses, 0.3% expanded urea 200, 0.5% stone powder, 0.3% salt, 0.3% dairy cow premix, 31% silage, 3.9% whole cottonseed and 11.6% alfalfa.

6. The use according to claim 4, characterized in that: The basic diet for beef cattle includes the following raw materials in percentage by mass: 50% corn, 11% soybean meal, 4% soybean hulls, 14% corn germ meal, 15% corn DDGS, 2% cane molasses, 0.7% expanded urea 200 type, 2% stone powder, 0.8% sodium chloride and 0.5% beef cattle premix.

7. A method for preventing or treating rumen acidosis in dairy cows, characterized in that: Feed a feed consisting of a basal diet and 20 g of chemical buffers per day to prevent rumen acidosis in lactating cows; feed a feed consisting of a basal diet and 40 g of chemical buffers per day to treat rumen acidosis in dairy cows.

8. A method for preventing or treating rumen acidosis in beef cattle, characterized in that: Feed a feed consisting of a basic diet and 20 g of chemical buffer every day to prevent rumen acidosis in fattening beef cattle; feed a feed consisting of a basic diet and 60 g of chemical buffer every day to treat rumen acidosis in beef cattle.

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