Composition with effects of strengthening, repairing and preventing hair breakage and application of composition

Abstract

The invention provides a composition with the effects of strengthening, repairing and preventing hair breakage and application of the composition. The composition is prepared from raw materials in parts by weight as follows: 18-20 parts of a surfactant, 5-7 parts of an okra extract, 4-6 parts of a hydrolyzed sheep placenta extract, 3-4 parts of panthenol, 2-3 parts of oat beta-glucan and 1-2 parts of water-soluble vitamin E. The okra extract is subjected to enzymolysis by adopting a buffer solution and mixed enzyme, and the mixed enzyme consists of cellulase, papain and acetylcholin esterase. The obtained composition is stable in property, and can effectively repair dry and cracked hair and prevent hair breakage.

Description

Technical Field

[0001] The invention relates to the field of hair care daily chemicals, and in particular to a composition with the functions of strengthening, repairing and preventing hair breakage and application thereof. Background Art

[0002] Hair damage may occur due to stress in life, heredity or improper use of shampoo and hair care products. The essence of hair damage is the destruction of keratin or reduction of toughness of hair, which affects hair quality and appearance. Shampoo compositions that prevent and repair dry and cracked hair are welcomed by consumers.

[0003] At present, the commercially available repair and anti-hair-breaking efficacy compositions have the following problems. First, the maintenance aids containing polypeptides and amino acids are widely used in shampoos. The protein molecular weight of polypeptide maintenance aids is large, and the permeability to hair is poor. It also has unstable properties and precipitation phenomena. The molecular weight of amino acid maintenance aids is too small, and there is a phenomenon of easy loss and low maintenance effect. Secondly, the selection of surfactants is crucial. The long-term use of surfactants extracted from petrochemical materials is irritating to the skin and mucous membranes, and there are shortcomings such as short storage time and easy deterioration, which affects its safety and the preservation of active ingredients. Nanoparticle surfactants with stable particles are favored by people, however, there is a risk of penetrating into the stratum corneum and entering the blood circulation. Third, Polygonum multiflorum has the effect of nourishing the scalp, but directly using Polygonum multiflorum as a raw material for nourishing the method has a low efficiency. It contains allergens, which can cause symptoms such as scalp itching, redness, and papules. Extracting the components effective for hair quality in Polygonum multiflorum has more application prospects. Therefore, in order to solve the above problems, the present application provides a shampoo composition for repairing dry and cracked hair and a preparation method thereof. Summary of the invention

[0004] In view of this, the present invention develops a shampoo composition for repairing dry and cracked hair and a preparation method thereof.

[0005] The technical solution of the present invention is achieved in this way:

[0006] A composition with strong repair and anti-breakage effects comprises the following raw materials in parts by weight: 18-20 parts of surfactant, 5-7 parts of okra extract, 4-6 parts of hydrolyzed sheep placenta extract, 3-4 parts of panthenol, 2-3 parts of oat beta-glucan and 1-2 parts of water-soluble vitamin E.

[0007] The preparation method of okra extract comprises the following steps:

[0008] S1. Wash the okra, remove the stems, freeze for 2-3 hours, and cut into 0.5-1.0 cm segments to obtain okra segments;

[0009] S2, thawing the okra segments, stirring at high speed, adding buffer and mixed enzyme for enzymolysis, and obtaining enzymolysis solution;

[0010] S3, adsorbing and filtering the enzymatic hydrolyzate to obtain okra extract.

[0011] Furthermore, in step S2, the mixed enzyme consists of cellulase, papain and acetylcholinesterase in a mass ratio of 9-11:4-6:0.5-0.7.

[0012] Furthermore, in step S2, the enzymolysis temperature is 25-45°C, the pH value is 4.5-7.5, and the time is 4-6 hours.

[0013] Further, in step S2, the buffer solution is prepared from diammonium hydrogen phosphate, ammonium dihydrogen phosphate and water, and the concentrations of the diammonium hydrogen phosphate and ammonium dihydrogen phosphate solutions are both 2 mol / L.

[0014] Furthermore, in step S3, the adsorption and filtration are performed, and the enzymatic hydrolyzate is adsorbed by a D-101 macroporous adsorption resin column, eluted and concentrated to obtain an okra extract.

[0015] Furthermore, the surfactant is composed of guar gum hydroxypropyltrimethylammonium chloride, cocamide MEA and cocamidopropyl betaine in a mass ratio of 1-1.5:1-1.5:1.

[0016] A composition with strong repair and anti-hair breakage effects comprises the following preparation steps: 18-20 parts of a surfactant, 5-7 parts of an okra extract, 4-6 parts of a hydrolyzed sheep placenta extract, 3-4 parts of panthenol, 2-3 parts of oat beta-glucan, and 1-2 parts of water-soluble vitamin E are mixed, added into 50-70 mL of pure water, stirred in a high-speed disperser for 30-35 minutes at a rotation speed of 400-600 rpm and a temperature of 15-30° C. to obtain the composition, sealed in a light-proof manner, and stored in a vacuum.

[0017] Compared with the prior art, the present invention has the following beneficial effects:

[0018] The combined invention of the present invention uses okra extract, hydrolyzed sheep placenta extract, panthenol, oat beta-glucan and water-soluble vitamins in combination, and the resulting composition has the effect of repairing and preventing hair breakage. The stability of the shampoo prepared by the raw materials, raw material ratio and preparation method of the present invention is significantly increased. The mean value of hair diameter, Young's modulus difference and keratin absorbance value of damaged hair diluted and soaked in the composition of the present invention are significantly increased. When okra extract is added, the hair diameter and keratin absorbance value are significantly increased. The composition of the present invention has stable properties and can effectively improve hair quality and repair damaged hair. DETAILED DESCRIPTION

[0019] In order to better understand the technical content of the present invention, specific examples are provided below to further illustrate the present invention. The experimental methods used in the examples of the present invention are all conventional methods unless otherwise specified.

[0020] The materials, reagents, etc. used in the embodiments of the present invention can be obtained from commercial channels unless otherwise specified. The cellulase manufacturer is Shanghai Quanyan Biotechnology Co., Ltd., CAS No. 9012-54-8, and the active ingredient content is 99%; the papain manufacturer is Shanghai Quanyan Biotechnology Co., Ltd., CAS No. 9001-73-4, and the active ingredient content is 99%; the acetylcholinesterase manufacturer is Wuhan Huaxiang Kejie Biotechnology Co., Ltd., pH value 6.0-8.0, and the active ingredient content is 99%.

[0021] Preparation Example 1

[0022] The preparation method of okra extract comprises the following steps:

[0023] Step (a): Wash the okra, remove the stems, freeze for 2 hours, and cut into 0.5 cm segments to obtain okra segments;

[0024] Step (ii): Thaw the okra segments, stir at high speed, add buffer and mixed enzyme for enzymolysis, the mixed enzyme is composed of cellulase, papain and acetylcholinesterase in a mass ratio of 9:4:0.5. The enzymolysis temperature is 28°C, the pH value is 5.5, and the time is 4 hours. The buffer is made of diammonium hydrogen phosphate, diammonium phosphate and water, and the concentrations of diammonium hydrogen phosphate and diammonium phosphate solutions are both 2moL / L. Obtain enzymolysis solution;

[0025] Step (iii): filtering the enzymatic hydrolysate by adsorption, using a D-101 macroporous adsorption resin column for adsorption, eluting and concentrating to obtain an okra extract.

[0026] Preparation Example 2

[0027] Step (a): Wash the okra, remove the stems, freeze for 3 hours, and cut into 1.0 cm segments to obtain okra segments;

[0028] Step (ii): Thaw the okra segments, stir at high speed, add buffer and mixed enzyme for enzymolysis, the mixed enzyme is composed of cellulase, papain and acetylcholinesterase in a mass ratio of 11:6:0.7. The enzymolysis temperature is 30°C, the pH value is 6.0, and the time is 6 hours. The buffer is made of diammonium hydrogen phosphate, diammonium dihydrogen phosphate and water, and the concentrations of diammonium hydrogen phosphate and diammonium dihydrogen phosphate solutions are both 2moL / L. Obtain enzymolysis solution;

[0029] Step (iii): filtering the enzymatic hydrolysate by adsorption, using a D-101 macroporous adsorption resin column for adsorption, eluting and concentrating to obtain an okra extract.

[0030] Preparation Example 3

[0031] Step (a): Wash the okra, remove the stems, freeze for 2.2 hours, and cut into 0.8 cm segments to obtain okra segments;

[0032] Step (ii): Thaw the okra segments, stir at high speed, add buffer and mixed enzyme for enzymolysis, the mixed enzyme is composed of cellulase, papain and acetylcholinesterase in a mass ratio of 10:5:0.6. The enzymolysis temperature is 28°C, the pH value is 6.5, and the time is 5 hours. The buffer is made of diammonium hydrogen phosphate, diammonium dihydrogen phosphate and water, and the concentrations of diammonium hydrogen phosphate and diammonium dihydrogen phosphate solutions are both 2moL / L. Obtain enzymolysis solution;

[0033] Step (iii): filtering the enzymatic hydrolysate by adsorption, using a D-101 macroporous adsorption resin column for adsorption, eluting and concentrating to obtain an okra extract.

[0034] Example 1

[0035] A composition with strong repair and anti-hair breakage effects comprises the following preparation steps: 18 parts of a surfactant, wherein the surfactant consists of guar gum hydroxypropyltrimethylammonium chloride, cocamide MEA and cocamidopropyl betaine in a mass ratio of 1:1:1; 5 parts of okra extract prepared in Preparation Example 1, 4 parts of hydrolyzed sheep placenta extract, 3 parts of panthenol, 2 parts of oat beta-glucan and 1 part of water-soluble vitamin E are mixed, added into 50 mL of pure water, stirred in a high-speed disperser for 30 minutes at a rotation speed of 400 rpm and a temperature of 15°C to obtain a composition, sealed in a light-proof manner, and stored in a vacuum.

[0036] Example 2

[0037] A composition with strong repair and anti-hair breakage effects comprises the following preparation steps: 20 parts of a surfactant, wherein the surfactant consists of guar gum hydroxypropyltrimethylammonium chloride, cocamide MEA and cocamidopropyl betaine in a mass ratio of 1.5:1.5:1; 7 parts of okra extract prepared in Preparation Example 2, 6 parts of hydrolyzed sheep placenta extract, 4 parts of panthenol, 3 parts of oat beta-glucan and 2 parts of water-soluble vitamin E are mixed, added into 70 mL of pure water, stirred in a high-speed disperser for 35 min at a speed of 600 rpm and a temperature of 30° C. to obtain a composition, sealed in a light-proof manner, and stored in a vacuum.

[0038] Example 3

[0039] A composition with strong repair and anti-hair breakage effects comprises the following preparation steps: 20 parts of a surfactant, wherein the surfactant consists of guar gum hydroxypropyltrimethylammonium chloride, cocamide MEA and cocamidopropyl betaine in a mass ratio of 1.2:1:1; 6 parts of okra extract prepared in Preparation Example 3, 5 parts of hydrolyzed sheep placenta extract, 3 parts of panthenol, 2 parts of oat beta-glucan and 1 part of water-soluble vitamin E are mixed, added into 60 mL of pure water, stirred in a high-speed disperser for 35 minutes at a speed of 500 rpm and a temperature of 25° C. to obtain a composition, sealed in a light-proof manner, and stored in a vacuum.

[0040] Comparative Example 1

[0041] The main difference between Comparative Example 1 and Example 3 is that okra extract is removed from the raw materials, and other raw materials and methods are the same as those in Example 3.

[0042] Comparative Example 2

[0043] The main difference between Comparative Example 2 and Example 3 is that the enzymatic hydrolysis step is removed from the okra extract preparation process, and the other raw materials and methods are the same as those in Example 3.

[0044] Comparative Example 3

[0045] The main difference between Comparative Example 3 and Example 3 is that the buffer solution is replaced with pure water in the step of preparing the okra extract, and the water-soluble vitamin E in the raw material is removed. Other raw materials and methods are the same as those in Example 3.

[0046] Comparative Example 4

[0047] The main difference between Comparative Example 4 and Example 3 is that the hydrolyzed sheep placenta extract and oat β-glucan are removed from the raw materials, and the other raw materials and methods are the same as those in Example 3.

[0048] Comparison

[0049] As a control, a commercially available shampoo for repairing dry and cracked hair was used, which was purchased from Guangzhou Jillian Daily Chemical Co., Ltd., and the amount used was consistent with that in the example.

[0050] test

[0051] (I) Index test:

[0052] The stability test was carried out in accordance with 6.2.1 and 6.2.3 of GB / T 29679-2013. The pH index was measured in accordance with 6.2.5 of GB / T29679-2013. The viscosity was measured using an NDJ-4 rotational viscometer. The foam content was measured in accordance with GB / T 13173-2021(11).

[0053] Table 1 Index content table

[0054]

[0055]

[0056] (II) Young's modulus and keratin test:

[0057] Screening damaged hair was randomly grouped according to the embodiment, comparative example and control. The diameter of damaged hair ranged from 65 to 75 μm, the number was 10, and a total of 80 test samples were obtained. The embodiment, comparative example and control compositions were diluted with pure water at a volume ratio of 1:10. The sample group hair was placed in the embodiment, comparative example and control compositions, then soaked for 15 minutes, and dried at room temperature, once a day, for a total of 7 days. The hair diameter was measured after 7 days, and the hair diameter, elongation and tension before and after the stretching method were statistically analyzed. The hair diameter was measured by the stretching method, and the Young's modulus value Y was calculated. Y = σ / ε; σ = F / S; ε = elongation of the hair after stretching (μm) / original length (μm); wherein Y is the Young's modulus value, σ is stress, ε is the elongation ratio, F is the tension on the hair, and S is the cross-sectional area of ​​the metal wire; Young's modulus difference (GPa) = Young's modulus value after treatment (GPa) - Young's modulus value before treatment (GPa).

[0058] Similarly, damaged hair was screened and randomly grouped according to the embodiment, comparative example and control. The diameter of damaged hair ranged from 65 to 75 μm, the number was 10, and a total of 80 test samples were obtained. The embodiment, comparative example and control compositions were diluted with purified water at a volume ratio of 1:10. The hair of the sample group was placed in the embodiment, comparative example and control compositions, then soaked for 15 minutes, and dried at room temperature, once a day for a total of 7 days. 14% SDS-PACGE separation gel was used for separation, and the keratin absorbance value after 7 days was measured and recorded.

[0059] Table 2 Damaged hair index parameter table

[0060]

[0061] (III) Hair care test:

[0062] Normal hair was randomly grouped according to the embodiment, comparative example and control. The diameter of normal hair ranged from 70-75 μm, the number was 10, and a total of 80 test samples were obtained. The embodiment, comparative example and control compositions were diluted with pure water at a volume ratio of 1:10. The hair of the sample group was placed in the embodiment, comparative example and control compositions, then soaked for 15 minutes and dried at room temperature, once a day for a total of 7 days. 14% SDS-PACGE separation gel was used for separation, and the keratin absorbance value after 7 days was measured and recorded. The test results show that after the composition is prepared according to the embodiment method,

[0063] Table 3 Normal hair index parameter table

[0064]

[0065] The test results are summarized. The present invention uses okra extract, hydrolyzed sheep placenta extract, panthenol, oat β-glucan and water-soluble vitamins in combination, and the resulting composition has the effect of repairing and preventing hair breakage. The composition prepared by the raw materials, raw material ratio and preparation method of the present invention has stable properties. The diameter, Young's modulus difference and keratin absorbance value of the damaged hair soaked after dilution of the composition of the present invention are significantly increased. In Comparative Example 1, okra extract is removed from the raw materials, and the enzymatic hydrolysis step is removed from the okra extract preparation step of Comparative Example 2. In Comparative Example 3, the buffer solution is replaced with pure water in the okra extract preparation step, and the water-soluble vitamin E in the raw materials is removed. In Comparative Example 4, hydrolyzed sheep placenta extract and oat β-glucan are removed from the raw materials. That is, the change of raw material components and preparation methods reduces the hair repair effect.

[0066] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A composition having the functions of strengthening, repairing and preventing hair breakage, characterized in that: The invention comprises the following raw materials in parts by weight: 18-20 parts of surfactant, 5-7 parts of okra extract, 4-6 parts of hydrolyzed sheep placenta extract, 3-4 parts of panthenol, 2-3 parts of oat beta-glucan and 1-2 parts of water-soluble vitamin E.

2. A composition having the functions of strengthening, repairing and preventing hair breakage according to claim 1, characterized in that: The preparation method of the okra extract comprises the following steps: S1. Wash the okra, remove the stems, freeze for 2-3 hours, and cut into 0.5-1.0 cm segments to obtain okra segments; S2, thawing the okra segments, stirring at high speed, adding buffer and mixed enzyme for enzymolysis, and obtaining enzymolysis solution; S3, adsorbing and filtering the enzymatic hydrolyzate to obtain okra extract.

3. The composition with the effects of strengthening, repairing and preventing hair breakage according to claim 2, characterized in that: Step S2, the mixed enzyme consists of cellulase, papain and acetylcholinesterase in a mass ratio of 9-11:4-6:0.5-0.

7.

4. The composition with the effects of strengthening, repairing and preventing hair breakage according to claim 2, characterized in that: Step S2, the enzymolysis temperature is 25-45°C, the pH value is 4.5-7.5, and the time is 4-6 hours.

5. The composition with the effects of strengthening, repairing and preventing hair breakage according to claim 2, characterized in that: Step S2, the buffer solution is prepared from diammonium hydrogen phosphate, ammonium dihydrogen phosphate and water, and the concentrations of the diammonium hydrogen phosphate and ammonium dihydrogen phosphate solutions are both 2 mol / L.

6. The composition with the effects of strengthening, repairing and preventing hair breakage according to claim 2, characterized in that: Step S3, the adsorption filtration, the enzymatic hydrolyzate is adsorbed by a D-101 macroporous adsorption resin column, eluted and concentrated to obtain an okra extract.

7. The composition with the effects of strengthening, repairing and preventing hair breakage according to claim 1, characterized in that: The surfactant consists of guar gum hydroxypropyltrimethylammonium chloride, cocamide MEA and cocamidopropyl betaine in a mass ratio of 1-1.5:1-1.5:

1.

8. The composition with the effects of strengthening, repairing and preventing hair breakage according to claim 1, characterized in that: The preparation method comprises the following steps: mixing 18-20 parts of a surfactant, 5-7 parts of an okra extract, 4-6 parts of a hydrolyzed sheep placenta extract, 3-4 parts of panthenol, 2-3 parts of oat beta-glucan and 1-2 parts of water-soluble vitamin E, adding the mixture into 50-70 mL of pure water, stirring the mixture in a high-speed disperser for 30-35 minutes at a rotation speed of 400-600 rpm and a temperature of 15-30 DEG C to obtain a composition, sealing the mixture in a light-proof manner and storing the mixture in a vacuum.

9. A composition prepared according to any one of claims 1 to 8, characterized in that The composition is diluted with purified water in a volume ratio of 1:8-12 before use, and 7-15 mL is used each time.

10. Use of the composition for strengthening, repairing and preventing hair breakage according to any one of claims 1 to 9 in repairing dry and cracked hair and preventing hair breakage.

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