Toilet and urine tester
By designing a urine tester that integrates a shell, detection mechanism, microfluidic chip and multiple pumps, the existing urine detection is solved, and efficient and accurate routine urine detection is achieved.
Patent Information
- Application Number
- CN202510361599.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-26
- Publication Date
- 2025-06-06
- Estimated Expiration
- 2045-03-26
AI Technical Summary
In the prior art, urine detection has time-consuming and labor-intensive problems, and there are few urine test instruments used for household use, so the detection accuracy is not enough to meet market demand.
A urine detector is designed, including a housing, detection mechanism, microfluidic chip, sample driving module, reagent driving module and air pump. The reagent, sample, water and air are driven by multiple pumps respectively, and the mixing chamber and mixing curve are used to improve the mixing effect of reagent and sample.
It improves the efficiency and accuracy of urine detection and can be suitable for routine urine detection, including 14 ascorbic acid tests, reducing bubbles in samples and water, and improving the accuracy of the detection.
Smart Images

Figure CN119881287B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of urine testing instruments, and in particular to a toilet and a urine testing instrument thereof. Background Art
[0002] As human life expectancy increases, the importance of health care and maintenance has received more and more attention. Urine can reflect a person's health status to a certain extent. Quantitative analysis of urine components can help us understand diseases such as the pancreas and kidneys. Urinalysis is an important indicator for detecting a person's physical condition. It can usually detect pH, protein, occult blood, specific gravity, glucose, ketone bodies, urobilinogen, nitrates, white blood cells, bilirubin and vitamin C, reflecting a series of indicators of the body. Urine tests are usually conducted in hospitals. Due to the shortage of medical resources, the examinees often have to queue up to register, see a doctor, pay fees, collect urine, wait for batches of urine tests, and then queue up to get the results, which is time-consuming and laborious.
[0003] At present, urine testers for home use have appeared on the market, but these urine testers have few detection items and their detection accuracy cannot meet market demand. Summary of the invention
[0004] The purpose of the present invention is to provide a toilet and a urine tester thereof to solve the problems of the prior art.
[0005] In order to solve the above technical problems, an embodiment of the present invention provides a urine test instrument, which comprises:
[0006] A shell, wherein a collection cavity is provided at the top of the shell, and the collection cavity is used to collect samples and water;
[0007] A detection mechanism, the detection mechanism is located in the housing and includes a test plate and a detection component, the test plate is provided with a test cavity, and the detection component is used to detect the liquid in the test cavity;
[0008] A microfluidic chip, the microfluidic chip is located in the housing and is provided with:
[0009] Main stream;
[0010] A sample flow channel, one end of which is connected to the main flow channel, and the other end of which is connected to the collection chamber through a first sample pipeline;
[0011] a plurality of reagent flow channels, one end of each of the plurality of reagent flow channels being connected to the main flow channel; and
[0012] An air flow channel, one end of which is connected to the main flow channel, and the other end of which is connected to the air duct;
[0013] A sample driving module, the sample driving module comprising a first sample pump, the first sample pump is located in the housing and connected to the first sample pipeline, and is operable to drive the sample in the collection chamber from the sample flow channel into the main flow channel;
[0014] A reagent driving module, the reagent driving module comprising a plurality of reagent capsules and a plurality of reagent pumps, the plurality of reagent capsules being connected to the other ends of the plurality of reagent flow channels through a plurality of reagent pipelines, the plurality of reagent pumps being located in the housing and connected to the plurality of reagent pipelines, and being operable to drive the reagents in the plurality of reagent capsules to enter the main flow channel from the reagent flow channels respectively;
[0015] An air pump is located in the housing and connected to the air pipe, and is operable to drive air into the main flow channel so that the reagent and sample in the main flow channel flow into the test cavity.
[0016] In one embodiment, the microfluidic chip is further provided with a clean water flow channel, one end of which is connected to the main flow channel, and the other end of which is connected to the collection chamber through a first clean water pipeline;
[0017] The urine test instrument includes a clean water driving module, the clean water driving module includes a first clean water pump, the first clean water pump is located in the housing and connected to the first clean water pipeline, and can operably drive the water in the collection chamber from the clean water flow channel into the main flow channel;
[0018] The air pump is operable to drive air into the main flow channel to make water in the main flow channel flow into the test chamber.
[0019] In one embodiment, the clean water drive module comprises:
[0020] A clean water container, wherein the top of the clean water container has an air outlet, and both ends of the first clean water pipeline are respectively connected to the clean water container and the clean water flow channel;
[0021] A second clean water pipeline, wherein two ends of the second clean water pipeline are respectively connected to the collection chamber and the clean water container;
[0022] a second clean water pump, the second clean water pump being connected to the second clean water pipeline and operable to drive the water in the collection chamber into the clean water container;
[0023] The first sample pump is operable to drive water in the clean water container from the clean water flow channel into the main flow channel.
[0024] In one embodiment, the sample driving module includes:
[0025] A sample container, wherein the top of the sample container has another air outlet, and both ends of the first sample pipeline are respectively connected to the sample flow channel and the sample container;
[0026] A second sample pipeline, two ends of which are respectively connected to the collection chamber and the sample container;
[0027] a second sample pump, the second sample pump being connected to the second sample pipeline and operable to drive the sample in the collection chamber into the sample container;
[0028] The first sample pump is operable to drive the sample in the sample container from the sample flow channel into the main flow channel.
[0029] In one embodiment, the urine testing instrument further includes an exhaust pipe, and two ends of the exhaust pipe are respectively connected to the air outlet of the clean water container and the top end of the collection chamber.
[0030] In one embodiment, the urine testing instrument further includes an exhaust pipe, and two ends of the exhaust pipe are respectively connected to the air outlet of the sample container and the bottom end of the collection chamber.
[0031] In one embodiment, the microfluidic chip is further provided with a mixing chamber, and two ends of the mixing chamber are respectively connected to the main channel and the test chamber;
[0032] The air pump is operable to drive air from the main channel into the mixing chamber, so that the reagent and sample in the main channel flow into the test chamber via the main channel and the mixing chamber in sequence.
[0033] In one embodiment, the microfluidic chip further comprises:
[0034] a mixing chamber, one end of which is in communication with the main flow channel; and
[0035] A mixing bend, the mixing bend is in the shape of a curved pipe and both ends of the mixing bend are respectively connected to the other end of the mixing chamber and the test chamber;
[0036] The air pump can be operated to drive air from the main channel into the mixing chamber and the mixing bend in sequence, so that the reagent and sample in the main channel flow into the test chamber via the main channel, the mixing chamber and the mixing bend in sequence.
[0037] In one embodiment, the main flow channel extends along a first direction, and the first direction is perpendicular to the vertical direction;
[0038] The mixing chamber comprises:
[0039] A first section, the bottom end of which is communicated with the main flow channel;
[0040] a mixing chamber, the top of which is connected to the top of the main channel, the mixing chamber comprising a first curved surface and a second curved surface, the first curved surface and the second curved surface being arranged opposite to each other, and the first curved surface is a curved surface formed by being recessed away from the second curved surface, and the second curved surface is a curved surface formed by being away from the first curved surface; and
[0041] A tail section, one end of which is connected to the bottom end of the mixing chamber, and the other end of which is communicated with the mixing bend.
[0042] In one embodiment, the mixing chamber further includes a third curved surface, the top end of the third curved surface is connected to the first section, the bottom end of the third curved surface is connected to the second curved surface, and the third curved surface is a curved surface that is concave toward the first curved surface.
[0043] In one embodiment, the diameter of the mixing curve ranges from 1 mm to 2 mm.
[0044] In one embodiment, the urine testing instrument further includes a filter portion, which is connected to the top opening of the collection chamber and is used to filter foreign matter.
[0045] In one embodiment, the microfluidic chip is further provided with a washing channel, one end of which is connected to the main channel, and the other end of which is connected to a container containing detergent through a washing pipe;
[0046] The urine testing instrument further comprises a washing pump, which is connected to the washing pipeline and is used for driving the detergent in the container to enter the main flow channel from the washing flow channel.
[0047] In one embodiment, a sewage outlet is provided at the bottom end of the collection chamber;
[0048] The urine testing instrument further comprises a sewage discharge pipe, wherein the sewage discharge pipe is connected with the collection chamber and the testing chamber.
[0049] In one embodiment, the urine testing instrument further includes a control module, which is electrically connected to the detection component, the first sample pump, the reagent pump and the air pump, and controls the detection component to detect the liquid in the test chamber and controls the operation of the first sample pump, the plurality of reagent pumps and the air pump.
[0050] The present invention also relates to a toilet, comprising the urine testing instrument mentioned above.
[0051] The urine tester of the present invention drives multiple reagents, samples, water and air respectively through multiple pumps, which can improve the driving efficiency. In addition, the mixing chamber and the mixing curve can also improve the mixing effect of the reagent and the sample as well as the water and the reagent. BRIEF DESCRIPTION OF THE DRAWINGS
[0052] Figure 1-Figure 3 Each of them is a stereoscopic diagram of a urine testing instrument according to an embodiment of the present invention.
[0053] Figure 4-Figure 7 yes Figure 1 An exploded view of the urine testing instrument in the illustrated embodiment.
[0054] Figure 8 and Fig. 9 yes Figure 1 A perspective view of the rear housing in the illustrated embodiment.
[0055] Fig.10 yes Figure 4 A perspective view of the microfluidic chip of the illustrated embodiment.
[0056] Fig.11 yes Fig.10 A diagram of the mixing chamber of the microfluidic chip of the illustrated embodiment.
[0057] Fig.12 yes Figure 1 An assembly diagram of a bracket, a clean water container, a sample container, a battery, a detection component, a circuit board, and a plurality of pumps in the illustrated embodiment.
[0058] Fig.13 and Fig.14 is a stereoscopic diagram of a microfluidic chip according to another embodiment of the present invention.
[0059] Fig.15 yes Fig.14 A cross-sectional view of the microfluidic chip of the illustrated embodiment along line AA.
[0060] Fig.16 It is a flow chart of a control method of a urine testing instrument according to an embodiment of the present invention.
[0061] Fig.17 It is a fluid circuit diagram of a urine testing instrument according to an embodiment of the present invention.
[0062] Figure numerals: 100, urine test instrument; 11, front shell; 12, rear shell; 121, connection part; 122, cover; 123, collection chamber; 124, groove; 125, pipe hole; 126, sewage outlet; 127, railing; 128, first exhaust hole; 129, second exhaust hole; 2, flow channel plate; 21, main flow channel; 22, sample flow channel; 23, air flow channel; 24, clean water flow channel; 25, mixing chamber; 251, first section; 252, mixing chamber; 253, tail section; 254, first arc surface; 255, second arc surface; 256, third arc surface; 257, second mixing chamber; 2571, first section; 2572, second 1. Section; 26. Mixing bend; 27. Washing channel; 28. Reagent channel; 3. Detection mechanism; 31. Detection component; 4. Clean water container; 401. First clean water pump; 402. First clean water pipeline; 403. Second clean water pipeline; 41. Second clean water pump; 42. First exhaust pipeline; 5. Sample container; 501. First sample pump; 502. First sample pipeline; 503. Second sample pipeline; 51. Second sample pump; 52. Second exhaust pipeline; 6. Bracket; 7. Reagent capsule; 8. Battery; 9. Circuit board; 101. Air pump; 102. Reagent pump; 103. Washing pump; DETAILED DESCRIPTION
[0063] In order to make the purpose, technical scheme and advantages of the present invention clearer, the following will be described in detail with reference to the accompanying drawings. However, it will be appreciated by those skilled in the art that in the various embodiments of the present invention, many technical details are provided in order to enable the reader to better understand the present application. However, even without these technical details and various changes and modifications based on the following embodiments, the technical scheme claimed for protection in the claims of the present application can be implemented.
[0064] Unless the context requires otherwise, throughout the specification and claims, the word "comprise" and variations such as "include" and "have" should be construed in an open, inclusive sense, ie, should be interpreted as "including, but not limited to."
[0065] The following will be described in detail with reference to the accompanying drawings to provide a clearer understanding of the purpose, features and advantages of the present invention. It should be understood that the embodiments shown in the accompanying drawings are not intended to limit the scope of the present invention, but are only intended to illustrate the essential spirit of the technical solution of the present invention.
[0066] References throughout the specification to "one embodiment" or "an embodiment" indicate that a particular feature, structure, or characteristic described in connection with the embodiment is included in at least one embodiment. Thus, the appearances of "in one embodiment" or "in an embodiment" in various places throughout the specification are not necessarily all referring to the same embodiment. Furthermore, the particular features, structures, or characteristics may be combined in any manner in one or more embodiments.
[0067] As used in this specification and the appended claims, the singular forms "a," "an," and "the" include plural referents unless the context clearly dictates otherwise. It should be noted that the term "or" is generally employed in its sense including "and / or" unless the context clearly dictates otherwise.
[0068] In the following description, in order to clearly show the structure and working mode of the present invention, many directional words will be used for description, but the words "front", "back", "left", "right", "outside", "inside", "outward", "inward", "up", "down", etc. should be understood as convenient terms and should not be understood as restrictive terms.
[0069] The present invention relates to a urine tester 100, which is small in size and high in efficiency, and can also remove bubbles in samples or water, and can be applied to routine urine tests, such as 14 ascorbic acid tests, including vitamins (C, VC), white blood cells (WBC), urobilinogen (URO), bilirubin (BIL), occult blood (BLD), nitrite (NIT), pH, protein (PRO), urine specific gravity (SG), urine ketone bodies (KET), urine glucose (GLU), urine creatinine (CR), urine calcium (CA) and microalbumin (MA) + urine uric acid + UACR (urine microalbumin / creatinine ratio) + UPCR (urine protein / creatinine ratio) + urine uric acid comprehensive value (based on CKD-EPI algorithm). The urine tester 100 of one embodiment of the present invention is described in detail below according to the accompanying drawings.
[0070] like Figure 1-5 As shown, the urine test instrument 100 includes a housing, a detection mechanism 3 located in the housing, a microfluidic chip, a sample drive module, a clean water drive module, a reagent drive module, multiple pipes, a battery 8, a sensor, a control module and a bracket 6. The housing is provided with a collection chamber 123 for collecting samples or water. The sample drive module includes a sample container 5, a pipe connecting the sample container 5 and the collection chamber 123 and a pump connected to the pipe, and a pipe connecting the sample container 5 and the sample flow channel of the microfluidic chip and a pump connected to the pipe.
[0071] like Figure 7 In the embodiment, the clean water driving module includes a clean water container 4, a pipe connecting the clean water container 4 and the collection chamber 123, and a pump connected to the pipe, and a pipe connecting the clean water container 4 and the clean water flow channel of the microfluidic chip, and a pump connected to the pipe.
[0072] The reagent driving module includes a plurality of reagent capsules 7, reagent pipelines respectively connecting the plurality of reagent capsules 7 with a plurality of reagent flow channels of the microfluidic chip, and a plurality of reagent pumps connected to the plurality of reagent pipelines.
[0073] like Figure 6 , Figure 7 In the figure, the clean water container 4 and the sample container 5 are used to store water and samples respectively. The reagent capsule 7 is used to hold the reagent for testing. The microfluidic chip is connected to the reagent capsule 7, the sample container 5 and the clean water container 4, and is used to mix the reagent and the sample, and the detection mechanism 3 includes a test plate and a detection component, wherein the test plate is provided with a test cavity, and the test cavity is connected to the microfluidic chip, and can receive the mixed liquid after the reagent and the sample are mixed. The detection component will detect the mixed liquid. The sensor is installed in the shell to detect the liquid in the collection cavity 123. The control module can control the movement of multiple pumps according to the signal of the sensor, or control the detection component 31 to detect. The battery 8 is used to power multiple pumps or the detection component 31. The bracket 6 is located in the shell, and is used to fix the detection mechanism 3, the battery 8, the control module, the reagent capsule 7, the sample container 5, the clean water container 4 and the microfluidic chip.
[0074] Specifically, the shell is used to accommodate the detection mechanism 3, the microfluidic chip, the sample drive module, the clean water drive module, the reagent drive module battery 8, the control module and the bracket 6, and the shell can also be installed on the inner wall of the toilet barrel, for example, it can be adhered to the inner wall of the toilet barrel.
[0075] In one embodiment, the housing includes a front housing 11 and a rear housing 12 connected to the front housing 11. The rear housing 12 is used to adhere to the inner wall of the toilet barrel. The front housing 11 can prevent foreign matter from entering the urine tester 100. Both the front housing 11 and the rear housing 12 have smooth curved surfaces protruding outward. After the rear housing 12 is adhered to the inner wall of the toilet barrel, the housing of the urine tester 100 is smooth as a whole and foreign matter will not be stuck. The entire front housing 11 and the rear housing 12 can be connected by screws or clamping, etc., and the specific connection method of the front housing 11 and the rear housing 12 is not limited.
[0076] A recessed collection chamber 123 is provided at the top of the rear shell 12. The collection chamber 123 is used to collect samples and water, and the sample is urine.
[0077] exist Figure 1-9 In the specific embodiment shown, the rear shell 12 includes a connecting portion 121 and a cover 122. The connecting portion 121 is generally conical and annular and has a smooth outer surface, that is, the diameter of the connecting portion 121 gradually decreases from the front end to the rear end, and the front end is fixedly connected to the front shell 11 and matches the outer surface of the front shell 11, and the outer surface looks like a smooth curved surface. The cover 122 is connected to the rear end of the connecting portion 121, and the rear end of the cover 122 is a curved surface protruding outward.
[0078] The collection chamber 123 is formed by the top of the cover 122 being concave and open at the top. The inner wall size of the collection chamber 123 is larger at the top to facilitate sample collection, while smaller at the bottom. The bottom of the collection chamber 123 is used to transport samples. Since part of the foam mixed in the sample collection process will be eliminated as the sample flows to the bottom, it can be avoided that the foam is transported to the test chamber to interfere with the test.
[0079] like Figure 5 and Fig. 9 In the embodiment, the inner wall of the cover 122 is further recessed to form two grooves 124, which are used to accommodate the clean water container 4 and the sample container 5. The two grooves 124 are distributed on both sides of the collection chamber 123, and the two grooves 124 and the collection chamber 123 share side walls on both sides along the first direction, so that the grooves 124 are adjacent to the collection chamber 123, and the outer sides of the grooves 124 are close to the radial outer sides of the cover 122. That is to say, this arrangement of the two grooves 124 and the collection chamber 123 makes the most efficient use of the volume of the cover 122, and can reduce the volume of the entire urine testing instrument 100.
[0080] The inner wall size of the collection chamber 123 gradually decreases from the top to the bottom to facilitate the collection of samples. Figure 5 and Figure 6 In the illustrated embodiment, the collection chamber 123 has a front and rear wall and two inner walls along the first direction. The rear wall is located on a side wall close to the inner wall of the toilet barrel, and the rear wall is a curved surface that protrudes slightly toward the rear end, so as to facilitate receiving more samples. The front wall and the rear wall are arranged opposite to each other. The two inner walls of the collection chamber 123 along the first direction are curved surfaces that protrude toward each other, that is, the width of the collection chamber 123 along the first direction gradually decreases from top to bottom.
[0081] like Figure 5 , Figure 7 , Figure 8 , Fig. 9In the embodiment, the two inner walls of the collection chamber 123 along the first direction are provided with five pipe holes 125, one of which is located at the top of one of the inner walls and close to the top opening of the collection chamber 123. The pipe hole 125 is used to communicate with the clean water container 4 to discharge the bubbles in the clean water container 4. The pipe hole 125 is defined as the first exhaust hole 128. The remaining four pipe holes 125 are located at the bottom of the collection chamber 123 and at both sides of the collection chamber 123 along the first direction. Two of the four pipe holes 125 are used to communicate with the sample container 5 and the clean water container 4 through pipes, and the other pipe hole 125 is connected to the test chamber through a sewage pipe. The last pipe hole 125 is used to communicate with the sample container 5 to facilitate the discharge of bubbles. The pipe hole 125 is defined as the second exhaust hole 129. The second exhaust hole 129 is located at the bottom of the collection chamber 123. Among the five pipeline holes 125 provided in the collection chamber 123 , four pipeline holes 125 are close to the bottom end of the collection chamber 123 , and one pipeline hole 125 is close to the top end of the collection chamber 123 .
[0082] like Figure 3 As shown, the bottom of the collection chamber 123 is also provided with a drain port 126, and the size of the drain port 126 is very small. When the collection chamber 123 receives the sample and the clean water, the liquid will not be lost quickly, but will be discharged slowly, which will not affect the collection of the sample. The operation of the pipe hole 125 and the drain port 126 will be described in detail below.
[0083] like Figure 3 As shown, the top opening of the collection chamber 123 is relatively large, and a filter unit is also provided at the top opening, the filter unit comprising a plurality of rails 127 and a filter net, the plurality of rails 127 are arranged at intervals along the first direction and connected to the top of the collection chamber 123, for blocking larger foreign matter. The filter net is located below the plurality of rails 127 and connected to the inner wall of the collection chamber 123, covering the entire top opening of the collection chamber 123, for fine filtering.
[0084] A sensor is also installed in the collection chamber 123 . The sensor is connected to the control module and can sense whether the liquid collected in the collection chamber 123 is a sample or water, and transmit the collected signal to the control module.
[0085] The bracket 6 is installed in the housing to support the clean water container 4, the sample drive module, the reagent drive module, the clean water drive module, the microfluidic chip, and the battery 8. The bracket 6 can be fixedly connected to the front housing 11 or the rear housing 12 by bolts, and the specific shape of the bracket 6 is not limited.
[0086] like Fig.10As shown, the microfluidic chip includes a flow channel plate 2 and a cover plate connected to the flow channel plate 2, wherein the flow channel plate 2 is a plate-shaped member extending along a first direction and is used to mix reagents and samples. Specifically, a concave main flow channel 21, a sample flow channel 22, a clean water flow channel 24, an air flow channel 23, a plurality of reagent flow channels 28 and a mixing chamber 25 are provided in the front surface or the rear surface of the flow channel plate 2, wherein the main flow channel 21 extends along the first direction, and the first direction is perpendicular to the vertical direction.
[0087] The cover plate covers and is connected to the front surface or the rear surface of the flow channel plate 2, and covers the main flow channel 21, the sample flow channel 22, the clean water flow channel 24, the air flow channel 23, the multiple reagent flow channels 28 and the mixing chamber 25. The cover plate and the main flow channel 21 cooperate to prevent the liquid in the main flow channel 21, the sample flow channel 22, the clean water flow channel 24, the air flow channel 23, the multiple reagent flow channels 28 and the mixing chamber 25 from overflowing.
[0088] One end of the main channel 21 extends to the outer end of the microfluidic chip along the first direction, and the other end extends to the approximate middle portion of the microfluidic chip.
[0089] One end of the sample flow channel 22, the clean water flow channel 24, the air flow channel 23 and the multiple reagent flow channels 28 are respectively connected to the main flow channel 21, and the other end extends to the top side or the bottom side of the microfluidic chip, and is used to communicate with the sample container 5, the clean water container 4 or the reagent capsule 7 through the pipeline. Figure 6 and Fig.10 In the illustrated embodiment, the sample flow channel 22 , the clean water flow channel 24 , the air flow channel 23 , and the plurality of reagent flow channels 28 are spaced apart at the top and bottom of the main flow channel 21 similar to tree branches. In other embodiments, other arrangements may also be used.
[0090] Specifically, if Fig.12 In the embodiment, the sample container 5 is connected to the sample flow channel 22 via a pipeline, which is defined as a first sample pipeline 502 , and the sample container 5 is connected to the collection chamber 123 via another pipeline, which is defined as a second sample pipeline 503 .
[0091] like Fig.12 In the figure, the first sample pipeline 502 is connected to one of the pumps, which is defined as the first sample pump 501 . The first sample pump 501 is used to drive the sample in the sample container 5 to flow into the sample flow channel 22 and enter the main flow channel 21 through the sample flow channel 22 .
[0092] like Fig.12 In the embodiment, the second sample pipeline 503 is connected to another pump, which is defined as a second sample pump 51 . The second sample pump 51 is used to drive the sample in the collection chamber 123 into the sample container 5 .
[0093] Similar to the sample container 5, Fig.12In the figure, the clean water container 4 is also connected to the clean water flow channel 24 and the collection chamber 123 through two pipes respectively. The pipe connecting the clean water container 4 with the clean water flow channel 24 is the first clean water pipe 402, and the pipe connecting the clean water container 4 with the collection chamber 123 is the second clean water pipe 403.
[0094] The first clean water pipeline 402 is connected to a pump, which is a first clean water pump 401 . The first clean water pump is used to drive the water in the clean water container 4 to enter the clean water flow channel 24 from the first clean water pipeline and then enter the main flow channel 21 .
[0095] The second clean water pipeline 403 is connected to another pump, which is a second clean water pump 41. The second clean water pump 41 is used to drive the water in the collection chamber 123 to flow from the second clean water pipeline into the clean water container 4.
[0096] In addition, if Figure 4 and Figure 8 As shown, air vents are respectively provided at the top of the clean water container 4 and the sample container 5, wherein the air vent of the clean water container 4 is connected to a pipe, which is a first exhaust pipe 42, and both ends of the first exhaust pipe 42 are respectively connected to the air vent of the clean water container 4 and the first exhaust hole 128 of the collection chamber 123.
[0097] like Figure 4 and Figure 5 As shown, the air outlet of the sample container 5 is connected to another pipe, which is defined as a second exhaust pipe 52. The two ends of the second exhaust pipe 52 are respectively connected to the air outlet of the sample container 5 and the second exhaust hole 129 of the collection chamber 123.
[0098] like Figure 4-Figure 10 As shown, the flow rate of the second sample pump 51 is greater than the flow rate of the first sample pump 501, and the flow rate of the second clean water pump 41 is greater than the flow rate of the first clean water pump 401. When in use, when the sensor senses that the sample is collected in the collection chamber 123, the control module can drive the second sample pump 51 to work after receiving the sensor signal. The second sample pump 51 has a large flow rate, and can extract a large number of samples from the collection chamber 123 into the sample container 5. Since bubbles will be generated during the rapid extraction process, after the bubbles and part of the sample enter the sample container 5, they can enter the collection chamber 123 through the air outlet at the top of the sample container 5 through the second exhaust pipe 52 and the second exhaust hole 129 at the bottom of the collection chamber 123, and then be discharged from the bottom of the collection chamber 123. The flow rate of the first sample pump 501 is relatively small, and the sample in the sample container 5 can be quantitatively extracted from the sample pipe into the sample flow channel 22, and then flow into the main flow channel 21. This setting can discharge the bubbles in the sample, ensure that no bubbles are generated in the sample extracted by the first sample pump 501, and avoid affecting the detection.
[0099] The same principle, such as Figure 4-Figure 10As shown, when it is necessary to extract water from the collection chamber 123 to clean the microfluidic chip and the test chamber, it is also necessary to use the second clean water pump 41 to extract a large amount of water from the collection chamber 123 into the clean water container 4, and then use the first clean water pump 401 to pump the water in the clean water container 4 to the clean water flow channel 24 and the main flow channel 21. The bubbles in the clean water container 4 can enter the first exhaust hole 128 at the top of the collection chamber 123 through the air outlet and the first exhaust pipe 42. Since the clean water has a washing effect, the bubbles and water in the first exhaust hole 128 can flow into the collection chamber 123 after entering the top of the collection chamber 123, and clean the collection chamber 123 again, so the first exhaust hole 128 is set at the top of the collection chamber 123. Since the bubbles and samples in the sample container 5 will cause pollution to the collection chamber 123, the second exhaust hole 129 needs to be set at the bottom of the collection chamber 123 to avoid pollution of the collection chamber 123.
[0100] When there are a lot of bubbles in the clean water used for washing, it will also affect the cleaning effect, so after the clean water container 4 is exhausted, the bubbles entering the main channel 21 can also be reduced.
[0101] Of course, in other embodiments, if it is ensured that there are no bubbles in the sample and water collected in the collection chamber 123, the clean water container 4 or the sample container 5 may not be provided. In other words, the first clean water pipeline 402 or the first sample pipeline 502 is directly connected to the collection chamber 123, and water or samples are directly pumped from the collection chamber 123 to the main flow channel 21 through corresponding pumps.
[0102] In addition, in order to fill the sample and water to the maximum extent without occupying too much internal space, the sample container 5 and the clean water container 4 try to match the shape of the groove 124.
[0103] The first sample pump 501 , the second sample pump 51 , the first clean water pump 401 and the second clean water pump 41 are preferably peristaltic pumps. The second sample pump 51 has a small flow rate and can accurately and quantitatively extract samples into the main channel 21 .
[0104] exist Fig.10 In the embodiment shown, the clean water channel 24 is located at the outer end of the main channel 21, that is, the clean water channel 24 and the main channel 21 both extend along the first direction, and the clean water channel 24 can also be regarded as a part of the outer end of the main channel 21. When it is clear, the entire main channel 21 can be clear and clean.
[0105] The reagent driving module is installed on the bracket, wherein multiple reagent capsules 7 are respectively fixed on the bracket 6, and are connected to multiple reagent channels 28 on the microfluidic chip through multiple reagent pipes, and the two ends of each reagent pipe are respectively connected to a reagent channel 28 and a reagent capsule 7, and each reagent pipe is respectively connected to a reagent pump 102.
[0106] like Fig.17 As shown, the reagent pump 102 can extract the reagent in the reagent capsule 7 into the reagent flow channel 28 and then flow into the main flow channel 21. According to the detection requirements, the reagent pump 102 can quantitatively extract the reagent in the reagent capsule 7 into the main flow channel 21, and the quantitative measurement is more accurate. The reagent pump 102 is also preferably a peristaltic pump.
[0107] The air flow channel 23 is connected to another pipeline, which is defined as an air pipeline. The air pipeline is also connected to a pump, which is defined as an air pump 101.
[0108] The air pump 101 can suck the external air from the air pipe and then enter the main channel 21 from the air channel 23. Of course, it can also operate in the reverse direction to extract the air in the main channel 21 from the air pipe to the outside. The air pump 101 is connected to the bracket 6, and is preferably a peristaltic pump.
[0109] The air flow channel 23 is close to the clean water flow channel 24 , that is, closer to the outer end of the sample flow channel. Air enters from the air flow channel 23 and can drive all reagents or samples entering the main flow channel 21 to flow from the main flow channel 21 into the mixing chamber 25 .
[0110] The above-mentioned pumps are all peristaltic pumps. In order to connect with the peristaltic pump, multiple pipelines need to be divided into two sections, and the two ends of the two ends are respectively connected to the two ends of the hose of the peristaltic pump.
[0111] Specifically, the mixing chamber 25 is connected to one end of the main channel 21 located in the middle of the microfluidic chip. The mixing chamber 25 has a certain accommodation space and can be used to mix samples and reagents.
[0112] After the second sample pump 51 draws the sample into the sample container 5, the first sample pump 501 can draw the sample in the sample container 5 into the sample flow channel 22, and then flow from the sample flow channel 22 into the main flow channel 21. Afterwards, the air pump 101 drives the air duct to absorb external air into the main flow channel 21, and pushes the sample in the main flow channel 21 toward the flow channel of the mixing chamber 25.
[0113] After the sample flows into the mixing chamber 25 , the first sample pump 501 also needs to reversely extract a portion of air from the main channel to the sample channel 22 to prevent the reagent from flowing into the sample channel 22 during the flow in the main channel 21 .
[0114] The reagent also flows into the mixing chamber 25 in the same way. Specifically, after the reagent pump 102 draws the reagent in the reagent capsule 7 to the main channel 21 through the reagent pipe, the air pump 101 draws external air into the main channel 21 to push the reagent in the main channel 21 into the mixing chamber 25. Then, the reagent pump needs to operate in reverse to draw a part of the air in the main channel 21 into the reagent flow channel 28.
[0115] The mixing chamber 25 is connected to the test chamber. After the reagent and the sample enter the mixing chamber 25, the air pump 101 can draw air into the mixing chamber 25 to drive the reagent and the sample to be swirled and mixed in the mixing chamber 25 to obtain a mixed liquid. The air pump 101 can drive the mixed liquid in the mixing chamber 25 into the test chamber.
[0116] As a preferred embodiment, the microfluidic chip is further provided with a mixing bend 26, the two ends of the mixing bend 26 are respectively connected with the test cavity and the mixing cavity 25, and the mixing bend 26 is a curved pipe.
[0117] After the reagent and sample enter the mixing chamber 25, the air pump can drive the reagent and sample in the mixing chamber 25 from the mixing chamber 25 into the mixing bend 26, and then return to the mixing chamber 25 from the mixing bend 26. After two or three rounds, the reagent and sample are fully mixed, and then the mixed liquid is driven from the mixing chamber 25 and the mixing bend 26 into the test chamber.
[0118] The sample or reagent needs to be pushed by the gas to mix in the mixing chamber 25, and the gas needs to be used to separate the sample and the reagent into the mixing chamber 25, so bubbles will be generated during the flow of the sample or reagent. However, after the sample and the reagent are mixed multiple times in the mixing chamber 25, the bubbles will be broken and will not flow into the test chamber to interfere with the detection.
[0119] exist Fig.10 In the illustrated embodiment, the mixing chamber 25 and the main channel 21 extend in a first direction, which is perpendicular to the vertical direction; the mixing chamber 25 includes a first section 251, a mixing chamber 252 and a tail section 253 which are connected to each other, wherein the first section 251 extends in the vertical direction, and the bottom end is connected to the main channel 21, and the top end is connected to the mixing chamber 252. The tail section extends in the first direction and is slightly lower than the main channel 21, and the two ends of the tail section 253 are connected to the mixing chamber 252 and the mixing bend 26 respectively.
[0120] The mixing chamber 252 is roughly baseball-shaped, with the top of the mixing chamber 252 connected to the first section 251 and the bottom connected to the tail section. Of the two side walls of the mixing chamber 252 disposed opposite to each other along the first direction, one side wall includes a first curved surface 254, and the other side wall includes a second curved surface 255 and a third curved surface 256 connected to each other.
[0121] The first curved surface 254 is a curved surface that is concave and curved away from the second curved surface 255. One end of the curved surface is tangent to a horizontal plane, and the other end is tangent to a vertical plane. As a preferred embodiment, the radius of the first curved surface 254 is in the range of 5mm-8mm, and the arc length is in the range of 7mm-10mm. More preferably, the radius of the first curved surface 254 is 5mm, and the arc length is 7.85mm. The first curved surface 254 is not directly connected to the first section 251 and the tail section. The top of the first curved surface 254 needs to be connected to the first section 251 through a horizontal inner wall, and the bottom end is connected to a vertical inner wall, and the vertical inner wall extends to the tail section.
[0122] The second curved surface 255 is a curved surface that is recessed away from the first curved surface 254, that is, the second curved surface 255 and the first curved surface 254 are both curved surfaces that are recessed outward, the bottom end of the second curved surface 255 is tangent to a horizontal plane, and the top end is tangent to a vertical plane, and the bottom end of the second curved surface 255 is connected to the tail section through a horizontal inner wall.
[0123] As a preferred solution, the radius of the second arc surface 255 is in the range of 5mm-8mm, and the arc length is in the range of 7mm-10mm. Furthermore, the radius of the second arc surface 255 is 5mm, and the arc length is 7.85mm.
[0124] The third curved surface 256 is a curved surface that curves toward the inside of the mixing chamber 25. The third curved surface 256 is located at the top of the second curved surface 255, and the bottom end of the third curved surface 256 is tangent to a vertical plane, which overlaps with the vertical plane tangent to the top of the second curved surface 255. The top of the third curved surface 256 is tangent to a horizontal plane, which is located below the horizontal plane tangent to the top of the first curved surface 254.
[0125] As a preferred solution, the radius of the third arc surface 256 is in the range of 0.75 mm to 2 mm, and the arc length is in the range of 1.5 mm to 3 mm. Furthermore, the radius of the third arc surface 256 is 2 mm, and the arc length is 3 mm.
[0126] The bottom end of the third curved surface 256 and the top end of the second curved surface 255 can be directly connected, or separated by a vertical inner wall. The height of the mixing chamber 25 along the vertical direction ranges from 8mm to 12mm, and the width along the first direction ranges from 7mm to 9mm. As a preferred embodiment, Fig.11 The height h1 of the mixing chamber 252 along the vertical direction is 9.75 mm, and the width w1 along the first direction is 8 mm.
[0127] The diameter of the mixing bend 26 is in the range of 1 mm to 2 mm, more preferably 1.5 mm.
[0128] Experiments have shown that the best mixing effect is achieved after the sample and reagent flow back and forth once in the mixing chamber 25 and the mixing bend 26, that is, the best mixing effect is achieved when the sample and reagent flow from the mixing chamber 25 into the mixing bend 26 and then return to the mixing chamber 25.
[0129] The volume of the mixed liquid required for the test is approximately 55 um. Many experiments have shown that the above-mentioned specifications and dimensions of the mixing chamber 25 and the mixing bend 26 not only ensure that the mixed liquid will not return to the main channel 21 during the mixing process, but also can be fully mixed.
[0130] In another embodiment, if Figure 13-Figure 15 As shown, the flow channel plate is provided with another mixing chamber, which is defined as the second mixing chamber 257. The second mixing chamber 257 also extends along the first direction and is connected to the main flow channel 21 at one end, and is connected to the test chamber at the other end. In addition, the top wall of the second mixing chamber 257 gradually increases from the two ends of the second mixing chamber 257 along the first direction to the middle, and the top wall of the second mixing chamber 257 is an arc surface. Of course, in this embodiment, the microfluidic chip is also provided with a clean water flow channel, a reagent flow channel, and an air flow channel connected to the main flow channel, and the operation is the same as the previous embodiment. Fig.12 and Fig.14 The flow channels are not shown.
[0131] Of course, a mixing bend (not shown) can also be set at the rear end of the second mixing chamber 257, and the two ends of the mixing bend are respectively connected to the second mixing chamber 257 and the test chamber. Similar to the previous embodiment, after the reagent and the sample flow into the second mixing chamber 257, the air pump drives the reagent and the sample from the second mixing chamber 257 to flow into the mixing bend, and repeatedly flows back to mix the reagent and the sample, and then drives the mixed liquid into the test chamber.
[0132] Preferably, if Fig.14 As shown, the width w2 of the second mixing chamber 257 along the first direction is 20 mm to 24 mm, and the height h2 of the second mixing chamber 257 along the vertical direction is 3 mm to 4 mm.
[0133] Preferably, if Fig.14 In the embodiment, the radius r of the main channel is in the range of 0.5mm-1mm, and the inner wall of the second mixing chamber 257 includes a first section 2571 protruding toward the outside and a second section 2572 recessed toward the inside. The first section 2571 and the second section 2572 are preferably arc surfaces, and the bottom end of the first section is connected to the inner wall of the main channel, and the top section is connected to the bottom end of the second section.
[0134] The first section and the second section are preferably arc surfaces, and the radius of the first section arc surface is preferably 3mm-5mm. The depth of the second section concave inward is greater than the depth of the first section concave inward, and the depth range d of the second section concave inward is 1.0mm-2.2mm.
[0135] The size of the mixing chamber determines the mixing effect and the backflow of the liquid, so the present invention obtains the mixing chamber size and the main channel size of the above data through multiple experiments, which can ensure the mixing effect.
[0136] like Fig.15 In the process, the liquid in the second mixing chamber 257 will not rise to the top wall of the second mixing chamber 257, that is, the liquid will not contact the second section 2572 of the second mixing chamber 257. The liquid has an angular flow effect, that is, the liquid will adhere to the inner wall of the second mixing chamber 257 during the flow process. When the liquid flows from the main channel 21 into the second mixing chamber 257, the surface of the liquid will form an arc surface that bends toward the outside at the end of the second mixing chamber 257 close to the main channel 21. When the liquid flows out of the second mixing chamber 257 to the mixing bend or the test chamber, that is, when the liquid flows from the second mixing chamber 257 to the outside, the surface of the liquid will also form an arc surface that is concave toward the outside at the end of the second mixing chamber 257 away from the main channel 21. The two arc surfaces formed by the liquid in the process of entering and flowing out of the second mixing chamber 257 enclose a roughly spherical space that accommodates bubbles. The bubbles will be broken in this space, thereby reducing the flow of bubbles from the second mixing chamber 257 into the test chamber.
[0137] After the sample and the reagent are mixed, the mixed liquid enters the test chamber from the second mixing chamber 257 and the mixing bend. Figure 4 In the embodiment shown, a section of pipe is connected between the test cavity and the mixing bend. In other embodiments, the test cavity can be directly set on the microfluidic chip, or the test plate can be set adjacent to the microfluidic chip, and the test cavity can also be directly connected to the mixing bend.
[0138] The test cavity is a cavity extending along a first direction and the width of the test cavity along the vertical direction gradually increases from both ends to the middle, the top wall of the test cavity gradually rises from both ends to the middle, and the bottom wall of the test cavity gradually decreases from both ends to the middle, and the bottom wall of the test cavity forms a pit, which is convenient for holding the mixed liquid for testing.
[0139] The detection component 31 includes a light source device and a photosensitive sensor, which are respectively arranged at corresponding positions of the test board. The test board is made of transparent material, the light source device is an LED light, which is used to illuminate the mixed liquid in the test cavity, and the photosensitive sensor is used to sense the light after the light source device illuminates the mixed liquid to detect the sample components.
[0140] After enough samples are collected in the collection chamber 123, the excess samples will be discharged from the sewage outlet 126 at the bottom of the collection chamber 123. When the operator flushes the toilet body with water, the collection chamber 123 will collect water. After the sensor detects the information of the collected water, it will transmit the information to the control module, and the control module controls the second clean water pump 41 to extract a large amount of water in the collection chamber 123 into the clean water container 4. After the detection is completed, the detection component 31 sends the detection information to the control module, and the control module controls the first clean water pump 401 to pump the water in the clean water container 4 to the clean water flow channel 24 and the main flow channel 21, and the air pump drives the water in the main flow channel 21 to the mixing chamber 25 and the mixing bend 26, and then enters the test chamber, and then is discharged from the test chamber.
[0141] Of course, the test chamber can be connected to one of the pipe holes 125 at the bottom of the collection chamber 123 through a sewage pipe. The air pump can pump the mixed liquid detected by the test chamber from the test chamber into the sewage pipe, and then flow from the sewage pipe to the collection chamber 123, and be discharged into the toilet through the sewage outlet 126 at the bottom of the collection chamber 123.
[0142] In another embodiment, the test plate is disposed adjacent to the rear shell 12 , and the test cavity may also be provided with a drain port 126 , which may extend directly to the outside of the rear shell 12 . After the test is completed, the mixed liquid in the test cavity may also be directly discharged from the drain port 126 .
[0143] As a preferred solution, Fig.10 As shown, the microfluidic chip is also provided with a washing channel 27, one end of the washing channel 27 is connected to the main channel 21, and the other end is connected to a container containing detergent through a washing pipe, which is defined as a washing container. The washing pipe is also connected to a washing pump 103.
[0144] After the detection is completed, before the control module drives the second clean water pump 41 to extract water from the clean water container 4, it first controls the washing pump 103 to extract the washing liquid in the washing container to the main channel 21, and then controls the second clean water pump 41 to extract the water from the clean water container 4 into the main channel 21, and the air pump drives the water and washing liquid in the main channel 21 to enter the mixing chamber 25, and repeatedly flows in the mixing chamber 25 and the mixing bend 26 to mix the water and the washing liquid. After the water and the washing liquid are mixed, the air pump is controlled to push the mixed washing liquid from the mixing chamber and the mixing bend into the test chamber in turn, and then discharged from the test chamber.
[0145] Optionally, the washing pump 103 drives the detergent in the container from the washing flow channel 27 into the main channel 21 to obtain a mixed washing liquid, and the air pump continues to push the mixed washing liquid into the test chamber through the mixing chamber 25 and the mixing bend 26 in turn, and then flows from the test chamber and the sewage pipe into the collection chamber 123, and finally is discharged from the sewage outlet 126 of the collection chamber 123 into the barrel of the toilet.
[0146] The present invention also relates to a control method of the urine test instrument 100. In one embodiment, the urine test instrument 100 includes a housing, a detection mechanism 3, a sensor, a microfluidic chip, a first sample pump 501, a reagent pump, an air pump and a control module, wherein a collection chamber 123 is provided at the top of the housing. The sensor is used to sense the sample and water in the collection chamber 123, and the sensor can be an infrared sensor or other sensors. The microfluidic chip is provided with a main flow channel 21, a mixing chamber 25, a sample flow channel 22, an air flow channel 23 and a plurality of reagent flow channels 28. The first sample pump 501 is connected to the first sample pipeline 502. A plurality of reagent pumps are connected to a plurality of reagent pipelines. The air pump is connected to the air pipeline.
[0147] like Fig.16 As shown, the control method comprises the steps of:
[0148] S1, after the sensor senses the information of the sample collected in the collection chamber 123, the information is transmitted to the control module, and the control module controls the first sample pump 501 to move the sample in the collection chamber 123 from the sample flow channel 22 into the main flow channel 21 according to the information of the sensor, and then controls the air pump to push the sample in the main flow channel 21 into the mixing chamber 25, and then controls the first sample pump 501 to draw a part of the air from the main flow channel 21 into the sample flow channel 22;
[0149] S2, the sensor senses that water is collected in the collection chamber 123 and transmits the information to the control module, the control module controls the reagent pump to drive the reagent in the reagent capsule 7 from the reagent flow channel 28 into the main flow channel 21, and then controls the air pump to push and suck air into the main flow channel 21, thereby pushing the reagent in the main flow channel 21 into the mixing chamber 25, and then controls the reagent pump to suck a part of the air from the main flow channel 21 into the reagent flow channel 28;
[0150] S3, the control module controls the air pump to repeatedly push the sample and reagent in the mixing chamber 25 to flow in the mixing chamber 25, and after obtaining the mixed liquid, controls the air pump to push the mixed liquid from the mixing chamber 25 to the test chamber;
[0151] S4. The control module controls the detection component 31 to detect the mixed liquid in the test cavity.
[0152] In a preferred embodiment, a sample container 5, a second sample pipeline 503 and a second sample pump 51 are disposed in the housing. The sample container 5, the second sample pump 51 and the second sample pipeline 503 have been described above and will not be described in detail.
[0153] In this case, in step S1 , the control module first controls the second sample pump 51 to drive the sample in the collection chamber 123 into the sample container 5 , and then controls the first sample pump to drive the sample in the sample container 5 from the sample flow channel 22 into the main flow channel 21 .
[0154] In another preferred embodiment, the microfluidic chip includes a curved mixing channel 26, and the two ends of the mixing chamber 25 are respectively connected to the main channel 21 and the mixing channel 26, and the two ends of the mixing channel 26 are respectively connected to the mixing chamber 25 and the test chamber;
[0155] In step S3, after the sample and reagent enter the mixing chamber 25 from the main channel 21, the control module controls the air pump to repeatedly push the sample and reagent in the mixing chamber 25 from the mixing chamber 25 into the mixing channel and then return to the mixing chamber 25. After obtaining the mixed liquid, the air pump is controlled to push the mixed liquid through the mixing chamber 25 and the mixing bend 26 to the test chamber in sequence.
[0156] Preferably, the microfluidic chip is further provided with a clean water channel 24 , one end of which is connected to the main channel 21 , and the other end is connected to the collection chamber 123 through a first clean water pipeline, and the clean water pipeline is connected to the first clean water pump 401 .
[0157] After the detection is completed, that is, after step S4, there is step S5, and after the detection component 31 detects the mixed liquid in the test chamber, the detection information is transmitted to the control module, and the control module controls the first clean water pump 401 to drive the water in the collection chamber 123 into the main channel 21. The control module controls the air pump to suck air into the main channel 21, and drives the water in the main channel 21 from the main channel 21 through the mixing chamber 25 and the mixing bend 26 to the test chamber in turn, and finally discharged from the test chamber.
[0158] Furthermore, if a clean water container 4, a second clean water pipe 403 and a second clean water pump 41 are further provided in the housing. The two ends of the second clean water pipe 403 are respectively connected to the collection chamber 123 and the clean water container 4. The two ends of the first clean water pipe 402 are respectively connected to the clean water container 4 and the clean water flow channel 24. The second clean water pump 41 is connected to the second clean water pipe 403.
[0159] In step S5, after the detection component 31 detects the mixed liquid in the test chamber, the control module first controls the second clean water pump 41 to drive the water in the collection chamber 123 to flow into the clean water container 4, and then controls the first clean water pump 401 to drive the water in the clean water container 4 from the clean water flow channel 24 into the main channel 21, and the air pump drives the water in the main channel 21 to pass through the mixing chamber 25, the mixing bend 26 and the test chamber in sequence, and finally discharged from the test chamber.
[0160] Furthermore, the microfluidic chip is also provided with a washing channel 27, which is connected to the main channel 21 and is connected to a container containing detergent through a washing pipe;
[0161] The urine test instrument 100 further includes a washing pump, and the washing pump is connected to the washing pipeline;
[0162] In step S5, after the detection component 31 detects the mixed liquid in the test chamber, the control module controls the washing pump to drive the detergent in the container from the washing flow channel 27 into the main channel 21, the second clean water pump 41 drives the water in the collection chamber 123 to flow into the clean water container 4, and the first clean water pump 401 drives the water in the clean water container 4 from the clean water flow channel 24 into the main channel 21. Then, the air pump sucks air into the main channel 21 and drives the water and detergent in the main channel 21 from the main channel 21 into the mixing chamber 25, the mixing bend 26 and then into the test chamber, and finally discharged from the test chamber.
[0163] Further, in step S5, the control module controls the air pump to suck air into the main channel 21, and drives the water and detergent in the main channel 21 to flow from the main channel 21 into the mixing chamber 25, and then controls the air pump to repeatedly push the water and detergent in the mixing chamber 25 from the mixing chamber 25 into the mixing curve 26 and then return to the mixing chamber 25 to obtain a mixed washing liquid, and then controls the air pump to push the mixed washing liquid through the mixing chamber 25 and the mixing curve 26 to the test chamber in sequence, and finally discharged from the test chamber.
[0164] Furthermore, the test chamber is connected to the collection chamber 123 through a sewage pipe, and a sewage outlet 126 is provided at the bottom end of the collection chamber 123 .
[0165] In step S5, the control module controls the air pump to suck air into the main channel 21, and drives the water and reagent in the main channel 21 from the main channel 21 through the mixing chamber 25 and the mixing bend 26 to the test chamber in sequence, and flows into the collection chamber 123 through the sewage pipe and is discharged from the sewage outlet 126.
[0166] All of the above-mentioned multiple pumps are preferably peristaltic pumps, especially pumps for driving reagents, because the use of peristaltic pumps can improve accuracy.
[0167] The control module is mounted on a circuit board 9, which is fixed to a bracket 6. The control module and the detection mechanism 3 are fixed to a substantially middle portion of the bracket 6, which is located at the rear end of the microfluidic chip.
[0168] After the urine tester 100 performs the test, the detected spectral data is sent to the computing device, and the computing device analyzes the spectral data of the urine of the current user to be tested to obtain the urine test data of the current user to be tested.
[0169] As a preferred solution, a wireless communication module (WIFI, 4G, 5G, etc.) is also provided in the housing, and the control module can send the spectral data or urine test data to the cloud server through the wireless communication module. After the sample information of the current user to be tested collected by the computing device reaches the required number of the currently configured user state prediction model, the sample information of the current user to be tested within the first set time length is automatically input into the user state prediction model, and the user state prediction model outputs the user physiological index data of the current user to be tested within the second set time length in the future under the current environmental conditions, thereby forming a continuous time period (first set time length + second set time length) of user physiological index data. Of course, the user can also trigger the user state prediction model through a user terminal (electronic devices such as mobile phones and tablets) for prediction. The specific scenario is that the user sends a prediction request to the computing device through the user terminal. When the computing device receives the user's prediction request, it determines the sample information of the user within the first set time length required for the prediction according to the identity information of the current user and inputs it into the user state prediction model to obtain the user physiological index data of the user's second set time length.
[0170] After the health classification model predicts the health type of the user to be tested, it can also analyze the predicted results of the user status in the area and conduct a comprehensive evaluation based on the physiological indicators, living habits, environmental factors and other information of the user to be tested. Based on the health classification of the user to be tested and the predicted results of the physiological indicators, the overall health status of the user to be tested can be determined, and it can be judged whether the user to be tested has potential health problems.
[0171] The collection chamber 123 of the present invention is configured with a larger opening at the top and a smaller opening at the bottom. The sample flows into the sample container 5 from the bottom of the collection chamber 123. During the process of the sample flowing from the top to the bottom, some bubbles can be reduced.
[0172] Moreover, a sample container 5 is used in the collection process, and an air outlet is provided in the sample container 5. The sample in the collection chamber 123 is extracted into the sample container 5 by the second sample pump 51, and the sample container 5 is extracted into the microfluidic chip by the first sample pump. This can reduce the bubbles in the sample during the collection process and transport them into the microfluidic chip, thereby improving the detection accuracy.
[0173] In addition, the microfluidic chip is provided with a mixing chamber 25 and a mixing bend 26. After the shape of the mixing chamber 25 is improved, it is not only convenient to mix the reagents and samples, but also uses an air pump to drive the reagents and samples to flow repeatedly in the mixing chamber 25 and the mixing bend 26, which can ensure the mixing of the reagents and samples, reduce the flow of bubbles into the test chamber, and improve the detection accuracy.
[0174] The urine tester 100 of the present invention drives multiple reagents, samples, water and air respectively through multiple pumps, which can improve the driving efficiency. In addition, the mixing chamber 25 and the mixing bend 26 can also improve the mixing effect of reagents and samples as well as water and reagents.
[0175] The present invention also relates to a toilet, which includes a barrel body and the above-mentioned urine tester, which is attached to the inner wall of the barrel body and close to the front end, the rear shell 12 of the shell is adhered to the inner wall of the barrel body of the toilet and the top opening of the collection chamber 123 is used to collect samples and water.
[0176] Preferred embodiments of the present invention have been described above in detail, but it should be understood that aspects of the embodiments can be modified, if necessary, to employ aspects, features and concepts of the various patents, applications and publications to provide further embodiments.
[0177] These and other changes can be made to the embodiments in light of the above detailed description.In general, in the claims, the terms used should not be considered limited to the specific embodiments disclosed in the specification and the claims, but should be construed to include all possible embodiments along with the full scope of equivalents to which these claims are entitled.
[0178] Those skilled in the art will appreciate that the above-mentioned embodiments are specific examples for implementing the present invention, and in actual applications, various changes may be made thereto in form and detail without departing from the spirit and scope of the present invention.
Claims
1. A urine tester, characterized in that: include: The shell comprises a front shell and a rear shell connected to the front shell, the top of the rear shell is provided with a concave collection cavity, the collection cavity is formed by the concave top of the cover and the top is open; the inner wall of the cover is also concave to form two grooves, the two grooves are used to accommodate the clean water container and the sample container; the collection cavity is used to collect samples and water; A test plate and a detection component, wherein the test plate is provided with a test cavity, and the detection component is used to detect the liquid in the test cavity; A microfluidic chip, the microfluidic chip is located in the housing and is provided with a main flow channel, a sample flow channel, a plurality of reagent flow channels, a clean water flow channel, and an air flow channel; One end of the sample flow channel is connected to the main flow channel, and the other end is connected to the collection chamber through a first sample pipeline; One end of the reagent flow channel is in communication with the main flow channel; One end of the clean water flow channel is connected to the main flow channel, and the other end is connected to the collection chamber through a first clean water pipeline; One end of the air flow channel is connected to the main flow channel, and the other end is connected to the air duct; a first sample pump, the first sample pump being located in the housing and connected to the first sample pipe, and being operable to drive the sample in the sample container from the sample flow channel into the main flow channel, and being operable to drive the water in the clean water container from the clean water flow channel into the main flow channel; The top of the sample container is provided with another air outlet, and both ends of the first sample pipeline are respectively connected with the sample flow channel and the sample container; A second sample pipeline, two ends of which are respectively connected to the collection chamber and the sample container; a second sample pump connected to the second sample pipeline and operable to drive the sample in the collection chamber into the sample container; a first clean water pump, the first clean water pump being located in the housing and connected to the first clean water pipeline and operable to drive the water in the collection chamber from the clean water flow channel into the main flow channel; A second clean water pipeline, both ends of which are respectively connected to the collection chamber and the clean water container; a second clean water pump connected to the second clean water pipeline and operable to drive the water in the collection chamber into the clean water container; The top of the clean water container is provided with an air outlet; An air pump is located in the housing and connected to the air pipe, and is operable to drive air into the main flow channel so that the reagent and sample in the main flow channel flow into the test cavity.
2. The urine tester according to claim 1, characterized in that: The urine test instrument also includes a reagent driving module, which includes a plurality of reagent capsules and a plurality of reagent pumps. The plurality of reagent capsules are connected to the other end of the plurality of reagent flow channels through a plurality of reagent pipes, respectively. The plurality of reagent pumps are located in the shell and connected to the plurality of reagent pipes, and can be operably driven to respectively drive the reagents in the plurality of reagent capsules from the reagent flow channels into the main flow channel.
3. The urine tester according to claim 1, characterized in that: The urine testing instrument further comprises an exhaust pipe, the two ends of which are respectively connected to the air outlet of the clean water container and the top end of the collection chamber.
4. The urine tester according to claim 1, characterized in that: The urine testing instrument further comprises an exhaust pipe, both ends of which are respectively connected to the air outlet of the sample container and the bottom end of the collection chamber.
5. The urine tester according to claim 1, characterized in that: The microfluidic chip is also provided with a mixing chamber, and two ends of the mixing chamber are respectively connected to the main channel and the test chamber; The air pump is operable to drive air from the main channel into the mixing chamber, so that the reagent and sample in the main channel flow into the test chamber via the main channel and the mixing chamber in sequence.
6. The urine tester according to claim 1, characterized in that: The microfluidic chip is also provided with: a mixing chamber, one end of which is in communication with the main flow channel; and A mixing bend, the mixing bend is in the shape of a curved pipe and both ends of the mixing bend are respectively connected to the other end of the mixing chamber and the test chamber; The air pump can be operated to drive air from the main channel into the mixing chamber and the mixing bend in sequence, so that the reagent and sample in the main channel flow into the test chamber via the main channel, the mixing chamber and the mixing bend in sequence.
7. The urine tester according to claim 6, characterized in that: The main flow channel extends along a first direction, and the first direction is perpendicular to the vertical direction; The mixing chamber comprises: A first section, the bottom end of which is communicated with the main flow channel; a mixing chamber, the top of which is connected to the top of the main channel, the mixing chamber comprising a first curved surface and a second curved surface, the first curved surface and the second curved surface being arranged opposite to each other, and the first curved surface is a curved surface formed by being recessed away from the second curved surface, and the second curved surface is a curved surface formed by being away from the first curved surface; and A tail section, one end of which is connected to the bottom end of the mixing chamber, and the other end of which is communicated with the mixing bend.
8. The urine tester according to claim 7, characterized in that: The mixing chamber further includes a third curved surface, the top end of the third curved surface is connected to the first section, the bottom end is connected to the second curved surface, and the third curved surface is a curved surface that is concave toward the first curved surface.
9. The urine tester according to claim 6, characterized in that: The diameter of the mixing bend ranges from 1 mm to 2 mm.
10. The urine tester according to claim 1, characterized in that: The urine testing instrument further comprises a filter portion, which is connected to the top opening of the collection chamber and is used for filtering foreign matter.
11. The urine tester according to claim 1, characterized in that: The microfluidic chip is also provided with a washing channel, one end of which is connected to the main channel, and the other end of which is connected to a container containing detergent through a washing pipeline; The urine testing instrument further comprises a washing pump, which is connected to the washing pipeline and is used for driving the detergent in the container to enter the main flow channel from the washing flow channel.
12. The urine tester according to claim 1, characterized in that: A sewage outlet is provided at the bottom end of the collection chamber; The urine testing instrument further comprises a sewage discharge pipe, wherein the sewage discharge pipe is connected with the collection chamber and the testing chamber.
13. The urine tester according to claim 2, characterized in that: The urine test instrument also includes a control module, which is electrically connected to the detection component, the first sample pump, the reagent pump and the air pump, and controls the detection component to detect the liquid in the test chamber and controls the first sample pump, the multiple reagent pumps and the air pump to operate.
14. A toilet, characterized in that: The toilet includes the urine testing instrument according to claim 1.
Citation Information
Patent Citations
Magnetic particulate chemiluminescent micro-fluidic chip for quantitatively detecting myohemoglobin
CN105195243A
Micro-fluidic chip detection method based on magnetic bead technology and reagent freeze-drying technology and micro-fluidic chip
CN110988331A