Automated analyzer

Abstract

In the automatic analysis device provided with the water-cooled reagent refrigerator, the outside air can be efficiently cooled and dried before being discharged into the internal space, so that condensation in undesired places can be inhibited. In an automatic analysis device provided with a reagent refrigerator for refrigerating a reagent, the reagent refrigerator comprises: a cooling water flow path for supplying cooling water to the outside of an inner wall of a space in which a reagent container is partitioned, and cooling the inner wall; and an air flow path that supplies air to the inside of the inner wall and that sets the space to a positive pressure, in which a cooling water inlet is formed at a predetermined location on the lower surface of the cooling water flow path disposed below the bottom surface of the space, a part of the air flow path disposed on the upper surface of the inner wall that divides the bottom surface of the space is located on the vertical projection of the cooling water inlet.

Description

Technical Field

[0001] The present invention relates to an automatic analyzer equipped with a reagent refrigerator. Background Art

[0002] The automatic analyzer reacts a sample (specimen) such as blood or urine with a reagent, and optically or electrically detects the reaction between the sample and the reagent. In such an automatic analyzer, the reagent used for the reaction is placed in a reagent container, and the reagent container is arranged on a reagent disk in a reagent refrigerator. In addition, in order to stably store the reagent, the internal space of the reagent refrigerator is refrigerated at, for example, about 5 to 12°C.

[0003] The reagent refrigerator is usually provided with a through hole for reagent suction, so as to suck the reagent from the reagent container in the reagent refrigerator. If the hot and humid outside air flows into the reagent refrigerator from the through hole, the following problem will occur: not only the temperature in the reagent refrigerator rises, but also the inflowing outside air is cooled below the dew point and condensation occurs. In order to deal with this problem, a technology is known, which introduces cooled outside air into the interior of the reagent refrigerator so that the pressure in the reagent refrigerator reaches above the atmospheric pressure, thereby suppressing the hot and humid outside air from flowing in from the through hole.

[0004] For example, Patent Document 1 describes introducing external air through an external air introduction path different from the through hole, or directly cooling the inner wall of the reagent refrigerator through a cooler such as a Peltier element. In addition, Patent Document 1 also discloses that an external air introduction path is provided along the bottom surface of the reagent refrigerator, and the external air exhaust port is formed toward a drain pipe so that condensation water generated by the introduction of external air can be immediately discharged. Prior art literature Patent Literature

[0005] Patent Document 1: International Publication No. 2021 / 182068 Summary of the invention Technical problem to be solved by the invention

[0006] In the reagent cold storage described in Patent Document 1, the external air introduction path is efficiently cooled by local temperature control of the cooler, so that the moisture contained in the external air is easy to condense in the external air introduction path. That is, in the reagent cold storage of Patent Document 1, the external air in a dry state is discharged to the internal space, so the condensation generated by the discharged external air is less. However, in the case of a water-cooled reagent cold storage using cooling water, the introduced external air is difficult to cool and dry, so it may not be possible to completely suppress the condensation caused by the external air discharged from the external air introduction path to the internal space.

[0007] An object of the present invention is to suppress condensation at an undesired location by efficiently cooling and drying the outside air before exhausting it into an internal space even in an automatic analyzer equipped with a water-cooled reagent refrigerator. Technical means for solving technical problems

[0008] In order to solve the above-mentioned problem, in the present invention, in an automatic analysis device equipped with a reagent cold storage for refrigerated reagents, the reagent cold storage has: a cooling water flow path, which supplies cooling water to the outer side of the inner wall that divides the space for storing reagent containers and cools the inner wall; and an air flow path, which supplies air to the inner side of the inner wall and sets the space to a positive pressure, a cooling water inlet is formed at a specified position of the lower surface of the cooling water flow path arranged below the bottom surface of the space, and a portion of the air flow path arranged on the upper surface of the inner wall that divides the bottom surface of the space is located on the vertical projection of the cooling water inlet. Effects of the Invention

[0009] According to the present invention, even in an automatic analyzer equipped with a water-cooled reagent refrigerator, it is possible to suppress condensation at an undesired location by efficiently cooling and drying the outside air before exhausting it into the internal space. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] Figure 1 It is a perspective view showing the overall structure of the automatic analyzer according to the present embodiment. Figure 2 It is a vertical cross-sectional view schematically showing the structure of the reagent refrigerator according to the present embodiment. Figure 3 This is a horizontal cross-sectional view schematically showing the structure of the reagent refrigerator according to the first embodiment. Figure 4 This is a horizontal cross-sectional view showing the flow of cooling water and air and the occurrence of condensation in Example 1. Figure 5 This is a horizontal cross-sectional view showing the flow of cooling water and air and the occurrence of condensation in Example 2. Figure 6 This is a horizontal cross-sectional view showing the flow of cooling water and air and the occurrence of condensation in Example 3. DETAILED DESCRIPTION

[0011] First, use Figure 1 An automatic analyzer according to an embodiment of the present invention will be described. Figure 1 It is a perspective view showing the overall structure of the automatic analyzer according to the present embodiment.

[0012] like Figure 1As shown, the automatic analyzer in this embodiment is a device that reacts a sample with a reagent in a reaction container 116 and measures the reaction liquid after the reaction. As a main structure, the automatic analyzer has a reagent refrigerator 1 ( Figure 1 The cover is omitted, and only the reagent disk 2, the reaction disk 101, the reagent transfer mechanism 102, the sample dispensing mechanism 103, 104, the reagent dispensing mechanism 105~108, the spectrophotometer 109, the stirring mechanism 110, the cleaning tanks 111~114, and the controller 115 are shown.

[0013] The reagent refrigerator 1 has a reagent disk 2 disposed therein, and the internal space is refrigerated. A plurality of reagent containers 4 containing reagents can be placed in a circle on the reagent disk 2 .

[0014] A plurality of reaction containers 116 for storing a mixed solution of a sample and a reagent are arranged in a circumferential shape on the reaction disk 101. A sample transport mechanism 102 for transporting a sample rack 118 carrying sample containers 117 is arranged near the reaction disk 101.

[0015] The sample dispensing mechanisms 103 and 104 that can rotate and move up and down are arranged between the reaction disk 101 and the sample conveying mechanism 102, and are provided with sample dispensing probes 103a and 104a. Each sample syringe (not shown) is connected to the sample dispensing probes 103a and 104a. The sample dispensing probes 103a and 104a move horizontally while drawing an arc with the rotation axis as the center, and move up and down to dispense the sample from the sample container 117 into the reaction container 116.

[0016] The reagent dispensing mechanisms 105 to 108 that can rotate and move up and down are arranged between the reaction disk 101 and the reagent disk 2, and are respectively provided with reagent dispensing probes 105a to 108a. The reagent dispensing probes 105a to 108a are moved up and down and horizontally by the reagent dispensing mechanisms 105 to 108. Each reagent syringe (not shown) is connected to the reagent dispensing probes 105a to 108a. The reagent, washing agent, diluent, pretreatment reagent, etc. sucked from the reagent container 4 via the reagent dispensing probes 105a to 108a are dispensed into the reaction container 116 by the reagent syringe.

[0017] Around the reaction disk 101, a spectrophotometer 109 for measuring the absorbance of light passing through the mixed solution in the reaction container 116, a stirring mechanism 1110 for mixing the sample and reagent dispensed into the reaction container 116, and a cleaning mechanism (not shown) for cleaning the inside of the reaction container 116 are arranged. In addition, cleaning tanks 111 to 114 for the reagent dispensing probes 105a to 108a are arranged within the operating range of the reagent dispensing mechanisms 105 to 108, respectively.

[0018] Each mechanism is connected to the controller 115, and its operation is controlled by the controller 115. The controller 115 as a control unit is composed of a computer, etc., and controls the operation of the above-mentioned mechanisms in the automatic analyzer and performs calculation processing to obtain the concentration of a predetermined component in a liquid sample such as blood or urine.

[0019] Next, the overall analysis process of the automatic analyzer in this embodiment is described in general. First, the sample in the sample container 117 on the sample rack 118 near the reaction disk 101, which is transported by the sample transport mechanism 102, is prevented from being dispensed into the reaction container 116 on the reaction disk 101 by the sample dispensing probes 103a and 104a of the sample dispensing mechanisms 103 and 104. Next, the reagent dispensing mechanisms 105 to 108 dispense the reagent for analysis from the reagent container 4 on the reagent disk 2 into the reaction container 116 into which the sample was previously dispensed, through the reagent dispensing probes 105a to 108a. Next, the stirring mechanism 110 stirs the mixed solution of the sample and the reagent in the reaction container 116.

[0020] Then, the light generated from the light source is transmitted through the reaction container 116 containing the mixed solution, and the luminosity of the transmitted light is measured by the spectrophotometer 109. The luminosity measured by the spectrophotometer 109 is sent to the controller 115 via the A / D converter and the interface. Then, the controller 115 performs calculations to obtain the concentration of a predetermined component in a liquid sample such as blood or urine, and displays the result on a display unit (not shown) or the like. In addition, in this specification, although an automatic analyzer that uses the spectrophotometer 109 to obtain the concentration of a predetermined component is described as an example, the technology disclosed in this specification can also be used for an immune automatic analyzer and a coagulation automatic analyzer that use other photometers to measure samples.

[0021] Next, use Figure 2 The structure of the reagent cold storage 1 will be described. Figure 2 1 is a vertical cross-sectional view schematically showing the structure of the reagent cold storage involved in the present embodiment. The reagent cold storage 1 is cylindrical in shape as a whole, and a reagent disk 2 which is circular in vertical projection (viewed from above) and can be rotated by a motor (not shown) is arranged in the space inside the reagent disk 2. On the reagent disk 2, a plurality of reagent containers 4 are arranged in a radially circular manner.

[0022] In addition, the bottom and the outer sides of the reagent cold storage 1 are surrounded by the heat insulating material 3, and the upper part is covered by the cover 5, so that the heat in the storage is not easy to escape to the outside, and the reagent container 4 can be efficiently refrigerated. In addition, the heat insulating material 3 is preferably composed of a material with low thermal conductivity such as expanded polystyrene and expanded polyurethane.

[0023] A cooling water flow path 8 is provided inside the heat insulating material 3, and the cooling water flow path 8 supplies cooling water to the outside of the inner wall 7 that partitions the internal space for storing the reagent container 4, so as to cool the inner wall 7. The inner wall 7 in this embodiment is common to the inner wall surface of the double wall forming the cooling water flow path 8, but it can also be composed of another wall surface that is closer to the inner side than the inner wall surface of the cooling water flow path 8. The reagent container 4 is refrigerated by transferring heat from the cooled inner wall 7 through convection or radiation of the air in the internal space.

[0024] A cooling water inlet 8a is formed at a predetermined position on the lower surface of the cooling water flow path 8 disposed below the bottom surface of the internal space, and a cooling water supply pipe 81 is connected to the cooling water inlet 8a. On the other hand, a cooling water outlet (not shown) is formed at another predetermined position on the lower surface of the cooling water flow path 8 disposed below the bottom surface of the internal space, and a cooling water outlet pipe 82 is connected to the cooling water outlet. In addition, the cooling water supply pipe 81 and the cooling water discharge pipe 82 penetrate the heat insulating material 3 located on the bottom surface of the reagent refrigerator 1 and are connected to a cooling water circulation device (not shown).

[0025] The bottom surface of the inner wall 7, that is, the cooling water flow path 8 arranged below the bottom surface of the internal space is inclined so that the outer diameter side is lower than the inner diameter side. Therefore, the condensation water generated in the internal space tends to flow to the outer diameter side from the bottom surface of the inner wall 7 due to gravity. Therefore, the upper opening 12a of the drain pipe 12 for discharging the condensation water is formed at a lower position on the outer diameter side of the inner wall 7.

[0026] The upper opening 12a is formed at the upper end side of the drain pipe 12 and connected to the bottom surface of the inner wall 7, and has a larger hole diameter than the hole diameter of the main body of the drain pipe 12. Then, an inclined surface whose hole diameter gradually decreases from the upper opening 12a is formed and connected to the main body of the drain pipe 12. Therefore, condensation water near the drain pipe 18 located on the bottom surface of the inner wall 7 is easily guided to the drain pipe 12. In addition, regarding the shape of the bottom surface of the inner wall 7, if it is also inclined so that only one point of the upper opening 12a of the drain pipe 12 is the lowest, condensation water is not easy to accumulate in places other than the upper opening 12a.

[0027] The cover 5 is formed with a reagent suction hole 6 through which the reagent dispensing probes 105a to 108a can pass. When the reagent in the specified reagent container 4 is sucked, the reagent container 4 is located under the vertical projection of the reagent suction hole 6 by the rotation of the reagent disk 2. In this state, the reagent dispensing probes 105a to 108a suck the reagent from the reagent container 4 through the reagent suction hole 6. However, when the hot and humid external air flows into the internal space of the reagent cold storage 1 from the reagent suction hole 6, the moisture contained in the external air cools in the internal space and condenses. Therefore, an air flow path is provided in the reagent cold storage 1 to supply air to the inner side of the inner wall 7 and set the internal space to a positive pressure, thereby suppressing the inflow of external air from the reagent suction hole 6.

[0028] The air flow routing duct 10 and the condensation promoting area 13 connected to the downstream side of the duct (refer to Figure 3 The duct 10 passes through the insulation material 3 and the inner wall 7 (cooling water flow path 8) on the bottom surface that divides the internal space from below the insulation material 3, is introduced into the internal space, and is arranged in contact with the bottom surface and side surface of the inner wall 7. A blower 11 is provided on the upstream side of the duct 10, and external air is supplied into the duct 10.

[0029] The outside air supplied to the duct 10 is cooled by the heat of the cooling water flowing through the cooling water flow path 8 outside the inner wall 7 while passing through the duct 10 and the condensation promoting area 13, and the moisture contained in the outside air condenses. Therefore, the dried air and the condensed water are discharged from the outlet 13a (refer to FIG. 1 ) formed on the downstream side of the condensation promoting area 13 by the air supplied from the blower 11. Figure 3 The condensed water discharged from the discharge port 13a is discharged from the upper opening 12a to the drain pipe 12. In particular, when the pipe 10 is introduced into the internal space, it passes through the inner diameter side of the drain pipe 12, so there is also an advantage that no other through holes are required to be provided on the inner wall 7.

[0030] Here, the specific structure and its effect for efficiently cooling the air and efficiently condensing the moisture contained in the air in the air flow path, particularly in the condensation promoting region 13, will be described below using Examples 1 to 3 as examples. Example 1

[0031] use Figure 3 and Figure 4 The reagent cold storage of Example 1 is described. Figure 3 is a horizontal cross-sectional view schematically showing the structure of the reagent refrigerator involved in Example 1, Figure 4 This is a horizontal cross-sectional view showing the flow of cooling water and air and the occurrence of condensation in Example 1.

[0032] First, the detailed structure of the cooling water flow path 8 is described. The cooling water supplied from the cooling water supply pipe 81 flows into the cooling water flow path 8 from the cooling water inlet 8a. In the cooling water flow path 8 arranged below the bottom surface along the bottom surface of the internal space, a plurality of partition members 9a extending in the radial direction of the reagent cold storage 1 are radially provided. Specifically, Figure 3 As shown, the first partition member 9a1 that creates a gap between the inner diameter side and the inner peripheral wall and the second partition member 9a2 that creates a gap between the outer diameter side and the outer peripheral wall are alternately arranged in the circumferential direction, and only the third partition member 9a3 near the cooling water inlet 8a extends to the entire radial area. Figure 4 As shown by the solid arrow in FIG. 1 , the cooling water in the cooling water flow path 8 flows from the cooling water inlet 8a toward the opposite side of the third partition member 9a3, meanders almost a circle, and is discharged from the cooling water outlet (not shown). As a result, the cooling water can completely and evenly cool the bottom surface of the inner wall 7. In addition, the cooling water flowing into the cooling water flow path 8 from the cooling water inlet 8a also flows through the cooling water flow path 8 arranged on the side of the internal space, and cools the side of the inner wall 7.

[0033] Furthermore, in addition to the partition member 9 a , a plurality of protrusions 9 b are provided in the cooling water flow path 8 . In addition, the protrusion 9b is formed with a screw hole from below, and the screw used when fixing the reagent refrigerator 1 to the installation table is inserted into the screw hole. By providing the protrusion 9b between the plurality of partition members 9a, the flow of cooling water in the cooling water flow path 8 is not only more winding, but also the cooling water can be guided to a desired area. In addition, the shape and arrangement of the partition member 9a and the protrusion 9b are not particularly limited, and a common shape may be used as long as it is a water flow limiting convex portion that limits the flow of cooling water.

[0034] Next, the structure of the duct 10 in the air flow path is described in detail. As described above, the duct 10 is introduced into the internal space from the upper opening 12a through the inner diameter side of the drain pipe 12, and is arranged in contact with the bottom and side surfaces of the inner wall 7. In addition, the material of the duct is preferably a material with high thermal conductivity, such as copper or aluminum, and is easy to be directly cooled by cooling water through the inner wall 7.

[0035] In addition, the longer the flow path of the outside air flowing in the duct 10 is, the longer the contact time and area between the duct 10 and the outside air are, and therefore, the temperature of the outside air in the stage of being discharged to the internal space decreases. That is, in order to prevent condensation on the reagent container 4 and the reagent disk 2, the flow path length of the duct 10 is preferably designed so that the temperature of the air discharged from the discharge port 13a is lower than that of the reagent disk 2 and the reagent container 4. In the present embodiment, the duct 10 roughly surrounds the outer diameter side end of the internal space along the side of the inner wall 7, and the flow path is ensured to be longer, so that even a water-cooled reagent refrigerator can cool the outside air to a certain extent.

[0036] However, when the flow path of the pipe 10 becomes longer, the pressure loss increases. Therefore, it is preferred that the blower 11 used for air supply can supply air in an environment with high pressure loss, for example, a diaphragm pump, a centrifugal fan, a piezoelectric fan, etc. In addition, in order to prevent dust and bacteria from invading the reagent cold storage 1, a filter can be set before the external air is introduced.

[0037] Next, the structure of the condensation promotion area 13 in the air flow path is described in detail. As described above, the outside air is also cooled in the duct 10, and the moisture contained in the outside air condenses, but since the cooling method uses cooling water, the cooling and drying of the outside air are not sufficient. Therefore, in this embodiment, the condensation promotion area 13 surrounded by a cover covering the upper surface side of the inner wall 7 that divides the bottom surface of the internal space is connected to the downstream side of the duct 10.

[0038] The condensation promotion area 13 is formed by the upper surface of the inner wall 7, the metal cover, and the elastic member connecting the edge of the lower surface of the cover to the upper surface of the inner wall 7. In addition, the material of the inner wall 7 (cooling water flow path 8) can also use a material with low thermal conductivity such as stainless steel and resin, but it is preferably a material with high thermal conductivity represented by copper and aluminum. The periphery of the vertical projection view of the condensation promotion area 13 is sealed by pressing the elastic member with the cover, so that the condensation water can be prevented from leaking out of the condensation promotion area 13.

[0039] In addition, the condensation promotion area 13 is in a shape that is bent from the upstream side to the downstream side in a vertical projection view. As long as it is a curved shape, it is not limited to the shape bent in the figure, and it can also be a shape of a drawn arc. In addition, the direction of the discharge port 13a formed on the downstream side of the condensation promotion area 13 is not coaxial with the direction of the downstream end of the pipe 10, and specifically, it is preferably an angle of more than 30° and less than 90°. As a result, the flow path in the condensation promotion area 13 becomes longer, and the convection of the air flowing from the pipe 10 into the condensation promotion area 13 is promoted in the condensation promotion area 13 and is cooled below the dew point, thereby also promoting the condensation of moisture contained in the air. In addition, if the cross-sectional area of ​​the discharge port 13a is smaller than the cross-sectional area of ​​the downstream end of the pipe 10, it is not easy for the air to be discharged from the condensation promotion area 13, thereby further promoting the cooling and condensation in the condensation promotion area 13. In addition, the cross-sectional shape of the discharge port 13a and the pipe 10 is, for example, circular, but can also be rectangular or trapezoidal. The discharge port 13a is formed toward the upper opening portion 12a of the drain pipe 12, and therefore, the condensed water discharged from the discharge port 13a is directly discharged without being accumulated in the internal space.

[0040] In addition, the direction of the discharge port 13a preferably has an angle of 45° to 80° relative to the side surface of the inner wall 7. That is, the angle formed by the straight line extending in the axial direction of the discharge port 13a and the tangent line at the intersection of the straight line and the inner wall 7 is preferably 45° to 80°. Thus, by discharging air obliquely from the condensation promoting area 13 relative to the inner wall 7 in a vertical projection view, the discharged air rotates and flows along the inner wall 7 and circulates efficiently in the internal space, so that the temperature gradient of the inner wall 7 becomes smaller and condensation in the internal space is suppressed.

[0041] Here, the cooling water with the lowest temperature among the cooling water supplied to the cooling water flow path 8 is the cooling water near the cooling water inlet 8a. Therefore, in this embodiment, a part of the condensation promotion area 13 formed on the upper surface of the inner wall 7 of the bottom surface dividing the internal space is located on the vertical projection of the cooling water inlet 8a. As a result, the air in the condensation promotion area 13 further promotes cooling and condensation compared with the air in the duct 10. In addition, in this embodiment, all vertical projections of the cooling water inlet 8a fall within the range of the vertical projection of the condensation promotion area 13, thereby further improving the cooling and condensation promotion effect.

[0042] According to this embodiment, even in a water-cooled reagent refrigerator using cooling water, the outside air can be efficiently cooled and dried before being discharged into the internal space, and the temperature of the outside air can be lower than the surface temperature of the reagent container 4, the reagent disk 2, and the inner wall 7 when discharged into the internal space. As a result, condensation can be prevented from occurring in the reagent refrigerator 1. Example 2

[0043] use Figure 5 The reagent cold storage of Example 2 is described. Figure 5 It is a horizontal cross-sectional view showing the flow of cooling water and air and the occurrence of condensation in Example 2. Example 2 is different from Example 1 in that the condensation promoting region 13 does not exist on the vertical projection of the cooling water inlet 8a.

[0044] Similar to Example 1, a plurality of water flow restricting convex parts such as a partition member 9a and a protrusion 9b are provided in the cooling water flow path 8 of this embodiment, but unlike Example 1, not only a partition member 9a but also a protrusion 9b is provided at a position close to the cooling water inlet 8a. Therefore, the two water flow restricting convex parts adjacent to the cooling water inlet 8a form a cooling water guide area that narrows the flow path width of the cooling water just after it flows into the cooling water flow path 8. Cooling water with a lower temperature partially flows into the cooling water guide area. Therefore, in this embodiment, at least a portion of the condensation promotion area 13 formed on the upper surface of the inner wall 7 of the bottom surface dividing the internal space is located on the vertical projection of the cooling water guide area. As a result, the air in the condensation promotion area 13 further promotes cooling and condensation compared to the air in the pipe 10. In addition, the direction of the cooling water flowing in the cooling water guide area is roughly opposite to the direction of the air flowing in the condensation promoting area 13 on the vertical projection of the cooling water guide area, and the flow rate of the cooling water whose flow path width is narrowed in the cooling water guide area also becomes higher, thereby further promoting the heat exchange between the cooling water and the air.

[0045] According to this embodiment, similarly to the first embodiment, the outside air can be efficiently cooled and dried in the condensation promoting region 13 before being discharged into the internal space, and the occurrence of condensation in an undesirable place can be suppressed. Example 3

[0046] use Figure 6 The reagent cold storage of Example 3 is described. Figure 6 1 is a horizontal cross-sectional view showing the flow of cooling water and air and the generation of condensation in Example 3. The structure of the cooling water flow path 8 of Example 3 is the same as that of Example 2. In Example 3, the difference from Example 2 is that a plurality of airflow restricting protrusions 13b for restricting the flow of air are formed in the condensation promoting area 13.

[0047] The airflow restricting convex portion 13b is formed so that the portion extending from one side to the other side and the portion extending from the other side to the one side are alternately staggered in the two side surfaces that divide the flow path in the condensation promoting area 13. The first airflow restricting convex portion 13b has a gap with the other side surface, and the second airflow restricting convex portion 13b has a gap with the one side surface. In addition, the upper end of each airflow restricting convex portion 13b contacts the above-mentioned cover, and the lower end contacts the cooling water flow path 8 as the inner wall 7.

[0048] According to this embodiment, the moving distance of the air in the condensation promotion area 13 becomes longer, so it can be cooled and dried more efficiently than in Example 2, and the effect of suppressing condensation is improved. In addition, in this embodiment, the airflow restriction protrusion 13b is set in the condensation promotion area 13 based on the structure of the reagent cold storage 1 involved in Example 2, but the airflow restriction protrusion 13b can also be set in the condensation promotion area 13 based on the structure of the reagent cold storage involved in Example 1.

[0049] In addition, the present invention is not limited to the above-mentioned embodiments, but also includes various modified examples. For example, in each embodiment, the air flow path is composed of the duct 10 and the condensation promotion area 13, but it can also be composed of only the duct 10. In this case, a part of the duct 10 (downstream side) is located on the vertical projection of the cooling water inlet 8a or the cooling water guide area. In addition, a part of the structure of a certain embodiment can be replaced with the structure of other embodiments, and the structure of other embodiments can be added to the structure of a certain embodiment. In addition, for a part of the structure of each embodiment, other structures can be added, deleted, or replaced. Description of symbols

[0050] 1 Reagent Refrigerator 2 Reagent disk 3. Insulation Materials 4 Reagent containers 5. Cover 6 Reagent suction hole 7 Inner wall 8 Cooling water path 8a Cooling water inlet 9a Separating member 9a1 1st partition member 9a2 Second partition member 9a3 The third partition member 9b Protrusion 10 Pipeline 11 Blower 12 Drain pipe 12a Upper opening 13 Condensation promoting area 13a Discharge outlet 81 Cooling water supply piping 82 Cooling water discharge pipe 101 Reaction Plate 102 Sample conveying mechanism 103, 104 Sample dispensing mechanism 103a, 104a Sample dispensing probe 105~108 reagent dispensing mechanism 105a~108a Reagent dispensing probe 109 Spectrophotometer 110 stirring mechanism 111~114 cleaning tank 115 Controller 116 Reaction vessel 117 Sample container 118 Sample rack.

Claims

1. An automatic analysis device, comprising a reagent refrigerator for refrigerating reagents, characterized in that: The reagent cold storage has: a cooling water flow path that supplies cooling water to the outside of an inner wall that partitions a space for storing a reagent container and cools the inner wall; and an air flow path that supplies air to the inner side of the inner wall and sets the space to a positive pressure, A cooling water inlet is formed at a predetermined position of the lower surface of the cooling water flow path arranged below the bottom surface of the space. A portion of the air flow path disposed on the upper surface of the inner wall of the bottom surface partitioning the space is located on a vertical projection of the cooling water inlet.

2. The automatic analysis device according to claim 1, characterized in that The air flow path has: a duct that penetrates the inner wall of the bottom surface that partitions the space and is introduced into the space, and is arranged to be in contact with the bottom surface or the side surface of the inner wall; and a condensation promoting region connected to the downstream side of the duct, An outlet for air and condensation water is formed on the downstream side of the condensation promoting area. A portion of the condensation promoting area is located on a vertical projection of the cooling water inlet.

3. The automatic analysis device according to claim 2, characterized in that The condensation promoting area is surrounded by a cover covering the upper surface side of the inner wall that covers the bottom surface that partitions the space.

4. The automatic analysis device according to claim 3, characterized in that All vertical projections of the cooling water inlet are located within the range of the vertical projection of the condensation promoting area.

5. An automatic analysis device having a reagent refrigerator for refrigerating reagents, characterized in that: The reagent cold storage has: a cooling water flow path that supplies cooling water to the outside of an inner wall that partitions a space for storing a reagent container and cools the inner wall; and an air flow path that supplies air to the inner side of the inner wall and sets the space to a positive pressure, The cooling water flow path disposed below the bottom surface of the space has a cooling water inlet and a water flow restriction protrusion for restricting the flow of cooling water. The plurality of water flow restriction protrusions adjacent to the cooling water inlet form a cooling water guide area that narrows the flow path width of the cooling water. A portion of the air flow path disposed on the upper surface of the inner wall of the bottom surface partitioning the space is located on a vertical projection of the cooling water guide region.

6. The automatic analysis device according to claim 5, characterized in that The air flow path has: a duct that penetrates the inner wall of the bottom surface that partitions the space and is introduced into the space, and is arranged to be in contact with the bottom surface or the side surface of the inner wall; and a condensation promoting region connected to the downstream side of the duct, An outlet for air and condensation water is formed on the downstream side of the condensation promoting area. At least a portion of the condensation promoting region is located on a vertical projection of the cooling water guiding region.

7. The automatic analysis device according to claim 6, characterized in that The condensation promoting area is surrounded by a cover covering the upper surface side of the inner wall that covers the bottom surface that partitions the space.

8. The automatic analysis device according to claim 2 or 6, characterized in that: The condensation promoting area is in a shape that curves from the upstream side to the downstream side in a vertical projection view.

9. The automatic analysis device according to claim 8, characterized in that The direction of the discharge port has an angle of 30° to 90° with respect to the direction of the downstream end of the duct.

10. The automatic analysis device according to claim 2 or 6, characterized in that: The cross-sectional area of ​​the discharge port is smaller than the cross-sectional area of ​​the downstream end of the pipe.

11. The automatic analysis device according to claim 3 or 7, characterized in that: The condensation promoting area is formed by the upper surface of the inner wall, the metal cover, and an elastic member connecting an edge portion of the lower surface of the cover and the upper surface of the inner wall.

12. The automatic analysis device according to claim 2 or 6, characterized in that: A plurality of airflow restricting protrusions that restrict the flow of air are formed in the condensation promoting region.

13. The automatic analysis device according to claim 2 or 6, characterized in that: The inner wall of the bottom surface that partitions the space is formed with an upper opening of a drain pipe for draining condensed water generated in the space. The discharge port is formed toward an upper opening portion of the drain pipe.

14. The automatic analysis device according to claim 2 or 6, characterized in that: The direction of the discharge port has an angle of not less than 45° and not more than 80° with respect to the side surface of the inner wall.

15. The automatic analysis device according to claim 1 or 5, characterized in that: The inner wall is formed by the cooling water flow path.

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