Tumor multi-primary determination method and system based on diagnosis package

Through the multi-primary tumor determination method and system based on the diagnosis package, the problem that the existing technology cannot efficiently manage and analyze tumor patient data is solved, accurate tumor data integration and efficient judgment accuracy are achieved, and the progress of relevant scientific research is promoted.

CN119905240APending Publication Date: 2025-04-29BEIJING CHILDRENS HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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Patent Information

Application Number
CN202411826791.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-12
Publication Date
2025-04-29

AI Technical Summary

Technical Problem

The existing technology cannot integrate and manage tumor patient data efficiently and accurately, resulting in the inability to improve the judgment accuracy of tumor recurrence or secondary determination, and the inability to use new data analysis techniques and pattern recognition algorithms to extract and analyze cases, which hinders the research progress of clinical epidemiological prediction science and the research progress of social health.

Method used

A method and system for determining tumors based on diagnosis packages is provided. Cases are obtained through diagnostic information output circuits, diagnostic packages are extracted according to case dimensions, ICD-O-3 anatomical classification and morphological classification are determined, tumors are determined, and the results are displayed through diagnostic information recording and displaying devices.

Benefits of technology

It has achieved efficient integration and management of tumor patient data, improved the accuracy of judging the time of tumor new occurrence, supported data analysis and pattern recognition, and promoted the progress of clinical epidemiology and social health research.

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Abstract

The invention discloses a tumor multi-primary determination method based on a diagnosis package, which comprises the following steps: S1, acquiring a case through a diagnosis information output circuit, and extracting the diagnosis package according to the dimension of the case in which a plurality of pieces of information related to tumor multi-primary determination exist; s2, determining corresponding ICD-O-3 anatomical classification and ICD-O-3 morphological classification on the basis of a plurality of pieces of information related to tumor multi-primary determination; s3, on the basis of the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification, carrying out tumor multi-primary determination; and S4, displaying information corresponding to the tumor multi-primary determination through the diagnosis information record display device. The invention further discloses a corresponding system, electronic equipment and a computer readable storage medium.
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Description

Technical Field

[0001] The present invention relates to the field of information intelligentization technology for medical information records, and in particular to a method and system for determining multiple primaries of a tumor based on a diagnosis package. Background Art

[0002] Diagnosis Related Groups (DRGs) are an important tool for measuring the quality and efficiency of medical services and for medical insurance payment. DRG is essentially a case combination classification scheme, that is, a system that divides patients into several diagnostic groups for management based on factors such as age, disease diagnosis, comorbidities, complications, treatment methods, severity and outcome of symptoms, and resource consumption.

[0003] In addition, the correct filling of the main diagnosis on the front page of the medical record means that the physician and the coder follow the regulations, the physician accurately selects and standardizes the main diagnosis on the front page of the inpatient medical record, and the coder accurately codes according to the disease classification code uniformly issued by the state. The correct rate of the main diagnosis filled in by the doctor = the number of discharged patient medical records with the main diagnosis filled in correctly on the front page of the medical record / the total number of discharged patient medical records in the same period; the correct rate of the main diagnosis coding by the coder = the number of discharged patient medical records with the main diagnosis coded correctly on the front page of the medical record / the total number of discharged patient medical records in the same period. The medical record reflects the rich diagnostic information of the patient. With the construction of the regional medical data platform, it is urgent to establish a complete patient diagnosis and treatment file. However, in the establishment of patient diagnosis and treatment files and the conduct of scientific research, the existing technology does not have a specific digital information extraction system to carry out automated information extraction. This leads to the inability to efficiently and accurately integrate and manage tumor patient data, the inability to improve the judgment accuracy of tumor recurrence or secondary determination, and the inability to use new data analysis technology and pattern recognition algorithms to extract and analyze case features, which hinders the research progress of clinical epidemiological prediction science and social health research progress. Therefore, based on this demand, a method and system for determining multiple primaries of tumors based on diagnostic packages are developed to facilitate the establishment of accurate patient diagnosis and treatment or health records, and to carry out diagnosis and treatment process tracking and clinical research. Summary of the invention

[0004] The purpose of the present invention is to provide a method and system for determining multiple primaries of a tumor based on a diagnostic package, so as to facilitate the subsequent accurate diagnosis and treatment process of the tumor.

[0005] In one aspect, the present invention provides a method for determining multiple primaries of a tumor based on a diagnostic kit, comprising:

[0006] S1, obtaining a case through a diagnostic information output circuit, and extracting a diagnostic package according to the case dimension, wherein the diagnostic package contains a plurality of pieces of information related to determining multiple primary tumors;

[0007] S2, determining a corresponding ICD-O-3 anatomical classification and an ICD-O-3 morphological classification based on a plurality of pieces of information related to the determination of multiple primaries of the tumor;

[0008] S3, determining the multiple primaries of the tumor based on the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification;

[0009] S4, displaying the information corresponding to the determination of the multiple primary sites of the tumor via the diagnostic information recording and displaying device.

[0010] Preferably, the S1 comprises:

[0011] S11, obtaining the case through the diagnostic information output circuit;

[0012] S12, extracting the diagnosis package according to the case dimension and confirming that there are multiple pieces of information related to the determination of multiple primary tumors in the diagnosis package.

[0013] Preferably, the ICD-O-3 anatomical classification of S2 includes:

[0014] Based on the first three digits of the ICD-O-3 anatomical site in the diagnosis package, ICD-O-3 anatomy is further classified into:

[0015] If the first three digits are C01 or CO2, the anatomical classification is C02.9;

[0016] If the first three digits are C00, C03, C04, C05, or CO6, the anatomical classification is C06.9;

[0017] If the first three digits are C09, C10, C12, C13, or C14, the anatomical classification is C14.0;

[0018] If the first three digits are C19 or C20, the anatomical classification is C20.9;

[0019] If the first three digits are C23 or C24, the anatomical classification is C24.9;

[0020] If the first three digits are C33 or C34, the anatomical classification is C34.9;

[0021] If the first three digits are C40 or C41, the anatomical classification is C41.9;

[0022] If the first three digits are C65, C66, C67, or C68, the anatomical classification is C68.9;

[0023] If the first three digits are C44, the anatomical classification is C44;

[0024] If the first three digits are C18, the anatomical classification is C18.

[0025] Preferably, the ICD-O-3 morphological classification of S2 includes:

[0026] The ICD-O-3 morphological classification is determined according to the ICD-O-3 morphological code in the diagnosis package, wherein the range represented by the ICD-O-3 morphological code in the diagnosis package includes all morphological codes within the range of all tumors; according to the ICD-O-3 morphological classification, systemic or multicentric tumors and unspecified tumor types can be determined; including:

[0027] If the ICD-O-3 morphology code is 8051-8084 or 8120-8131, the ICD-O-3 morphology category is 1;

[0028] If the ICD-O-3 morphology code is 8090-8110, the ICD-O-3 morphology category is 2;

[0029] If the ICD-O-3 morphology code is 8140-8149, 8160-8162, 8190-8221, 8260-8337, 8350-8551, 8570-8576, or 8940-8941, the ICD-O-3 morphology category is 3;

[0030] If the ICD-O-3 morphology code is 8030-8046, 8150-8157, 8170-8180, 8230-8255, 8340-8347, 8560-8562, or 8580-8671, the ICD-O-3 morphology category is 4;

[0031] If the ICD-O-3 morphology code is 8010-8015, 8020-8022, or 8050, the ICD-O-3 morphology category is 5;

[0032] If the ICD-O-3 morphology code is 8680-8713, 8800-8921, 8990-8991, 9040-9044, 9120-9125, 9130-9136, 9141-9252, 9370-9373, or 9540-9582, the ICD-O-3 morphology category is 6;

[0033] If the ICD-O-3 morphology code is 9050-9055, the ICD-O-3 morphology category is 7;

[0034] If the ICD-O-3 morphology code is 9840, 9861-9931, 9945-9946, 9950, 9961-9964, or 9980-9987, the ICD-O-3 morphology category is 8;

[0035] If the ICD-O-3 morphology code is 9670-9699, 9728, 9731-9734, 9761-9767, 9769, 9823-9826, 9833, 9836, or 9940, the ICD-O-3 morphology category is 9;

[0036] If the ICD-O-3 morphology code is 9700-9719, 9729, 9768, 9827-9831, 9834, 9837, or 9948, the ICD-O-3 morphology category is 10;

[0037] If the ICD-O-3 morphology code is 9650-9667, the ICD-O-3 morphology category is 11;

[0038] If the ICD-O-3 morphology code is 9740-9742, the ICD-O-3 morphology category is 12;

[0039] If the ICD-O-3 morphology code is 9750-9758, the ICD-O-3 morphology category is 13;

[0040] If the ICD-O-3 morphology code is 9590-9591, 9596, 9727, 9760, 9800-9801, 9805, 9820, 9832, 9835, 9860, 9960, 9970, 9975, or 9989, the ICD-O-3 morphology category is 14;

[0041] If the ICD-O-3 morphology code is 9140, the ICD-O-3 morphology category is 15;

[0042] If the ICD-O-3 morphology code is 8720-8790, 8930-8936, 8950-8983, 9000-9030, 9060-9110, 9260-9365, or 9380-9539, the ICD-O-3 morphology category is 16;

[0043] If the ICD-O-3 morphology code is 8000-8005, the ICD-O-3 morphology category is 17.

[0044] Preferably, S3 includes:

[0045] S31, performing a first judgment according to the ICD-O-3 anatomical classification, including:

[0046] If the ICD-O-3 anatomical classification includes C44 or C18, it is judged as multiple primary;

[0047] If the ICD-O-3 anatomical classification does not include C44 or C18, continue to judge;

[0048] S32, performing a second judgment based on the same ICD-O-3 anatomical classification, wherein the second judgment is performed based on the ICD-O-3 morphological classification, including:

[0049] If the ICD-O-3 morphological classification is the same, it is judged as single;

[0050] If the ICD-O-3 morphological classification is different, continue to judge;

[0051] S33, performing a third judgment according to the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification, including:

[0052] If the ICD-O-3 morphological classification is different and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification group 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification group 5, 14, 17, it is judged to be multiple primary;

[0053] If the ICD-O-3 morphological classification is the same and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification groups 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification 5, 14, 17, it is judged as a single tumor;

[0054] S34, performing a fourth judgment according to the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification, including:

[0055] If the ICD-O-3 morphological classification is different and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification group 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification group 5, 14, 17, it is judged to be multiple primary;

[0056] If the ICD-O-3 morphological classification is the same and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification groups 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification 5, 14, and 17, it is judged to be a single tumor.

[0057] Preferably, the diagnostic information output circuit reads the enable signal, timing signal, reset signal, and clock signal in the control device to monitor whether a problem occurs; determines the operating status and fault status of the control device when it is started based on the information of each electrical signal; generates maintenance diagnostic information based on the judgment result, and outputs the diagnostic information to the outside as an electrical signal via the power interface of the first universal interface through the first control switch; the diagnostic information output circuit sets the power interface to the power pull-up state through the second control switch, thereby setting it to the signal input state, and detecting the response signal from the external diagnostic circuit; the diagnostic information output circuit reads the data pin of the first universal interface, monitors whether a normal external device other than the diagnostic information recording and display device is connected to the first universal interface, and controls the update of the patient medical record information data and the output of the modification information according to the monitoring result.

[0058] Preferably, the diagnostic information recording and display device has a diagnostic information recording and display circuit and a second universal interface, and is connected to a control device via a USB cable for use; the diagnostic information recording and display device is provided with a data pin connected to the second universal interface, and by detecting the data pin, the diagnostic information output circuit of the control device can determine the working status of the external device and the diagnostic information recording and display device; a personal computer or a numerical control device with a display is connected to the diagnostic information recording and display circuit; the diagnostic information recording and display circuit monitors the power interface of the second universal interface, analyzes the electrical signal input via the power interface, and obtains the diagnostic information of the control device generated by the control device; the obtained diagnostic information is output to the personal computer or the numerical control device, and displayed on the display via the personal computer or the numerical control device, thereby notifying the user who extracted the patient diagnostic package information; the diagnostic information recording and display circuit generates a response signal for the diagnostic information according to the third control switch, and outputs it to the diagnostic information output circuit via the power interface of the second universal interface.

[0059] A second aspect of the present invention is to provide a system for determining multiple primary tumors based on a diagnostic package, comprising:

[0060] An information extraction module (101) is used to obtain a case through a diagnostic information output circuit, and extract a diagnostic package according to the case dimension, wherein the diagnostic package contains a plurality of pieces of information related to the determination of multiple primary tumors;

[0061] A classification module (102), configured to determine a corresponding ICD-O-3 anatomical classification and an ICD-O-3 morphological classification based on a plurality of pieces of information related to the determination of multiple primaries of a tumor;

[0062] A tumor multiple primary determination module (103), used for determining the multiple primary locations of tumors based on the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification;

[0063] An information display module (104) is used to display the information corresponding to the determination of multiple primary sites of the tumor through the diagnostic information recording and display device.

[0064] A third aspect of the present invention provides an electronic device, comprising a processor and a memory, wherein the memory stores a plurality of instructions, and the processor is configured to read the instructions and execute the method described in the first aspect.

[0065] A fourth aspect of the present invention provides a computer-readable storage medium, wherein the computer-readable storage medium stores a plurality of instructions, and the plurality of instructions can be read by a processor and execute the method described in the first aspect.

[0066] The method, system, electronic device, and computer-readable storage medium provided by the present invention have the following beneficial technical effects:

[0067] (1) Cancer patient data integration and management

[0068] By integrating multiple data sources, including basic information of cancer patients, admission records, discharge records, test results, treatment plans, etc., we can achieve comprehensive integration and management of cancer patients' hospitalization data, greatly improving the efficiency and accuracy of data management.

[0069] (2) Improving the accuracy of determining the time of new tumor onset

[0070] By integrating multiple diagnostic judgments and data analysis algorithms, we can improve the ability to judge key time points in the tumor development process and increase the accuracy of judging the time of new tumor onset. This helps to integrate professional knowledge from different fields to improve the understanding and judgment of tumor onset time.

[0071] (3) Research data analysis and pattern recognition

[0072] Using advanced data analysis technology and pattern recognition algorithms, we extract and analyze tumor development patterns from a large number of hospitalized cases, including the characteristics of single and multiple primary tumors. This analysis helps to gain a deeper understanding of the biological characteristics and pathological mechanisms of tumors.

[0073] (4) Promotion of basic science and big data analysis

[0074] It will help promote progress in basic scientific research, such as the mechanism of tumor development and the differences between different types, and in the field of tumor epidemiology and geographical distribution. These research results are of great significance for future epidemiological predictions and health policy formulation.

[0075] (5) Research on epidemiology and social health impact

[0076] The data on permanent residence extracted from hospitalized cases are used to conduct research and analysis on cancer epidemiology. These data can reveal the differences in cancer incidence and related factors between different geographical regions, and help formulate public health policies and resource allocation strategies.

[0077] (6) Improve scientific research efficiency

[0078] It involves developing personalized data query and analysis tools, allowing researchers to customize queries on cancer patient data based on specific research needs. This tool helps improve data mining efficiency and the depth of data-driven research. Researchers can quickly retrieve and call the required case data, support a variety of data analysis tools, greatly shorten the time for data processing and analysis, improve scientific research efficiency, and improve the effective use of research resources, thereby promoting the progress of cancer research. In addition, the data visualization function provided by the system helps researchers understand data trends and results more intuitively.

[0079] (7) Improve data security

[0080] Multiple encryption technologies and strict authority management mechanisms are used to ensure the security and privacy of patient data, prevent unauthorized access and data leakage, and comply with relevant laws and regulations.

[0081] (8) Identification of survival status of cancer patients

[0082] By analyzing the patient's hospitalization records and follow-up information, the key factors that affect the patient's survival status can be identified. These models can help researchers understand the possible influencing factors of survival outcomes, thereby promoting the progress of medical research. Including long-term survival status monitoring and evaluation methods, by continuously collecting and analyzing patients' hospitalization data, and evaluating patients' treatment and survival outcomes, to provide a scientific basis for disease management strategies.

[0083] (9) Promotion of scientific research methods

[0084] It will help promote the development of customized query methods for tumor data, including improvements in data privacy protection and query efficiency, and provide technical support for future big data-driven medical research. BRIEF DESCRIPTION OF THE DRAWINGS

[0085] Figure 1 It is a flow chart of a method for determining multiple primaries of a tumor based on a diagnostic package according to a preferred embodiment of the present invention;

[0086] Figure 2 It is a principle flow chart of a method for determining multiple primaries of a tumor based on a diagnostic package according to a preferred embodiment of the present invention;

[0087] Figure 3It is a principle architecture diagram of a tumor multi-primary determination system based on a diagnostic package according to a preferred embodiment of the present invention;

[0088] Figure 4 A schematic structural diagram of an embodiment of an electronic device provided by the present invention. DETAILED DESCRIPTION

[0089] The specific implementation of the present invention is further described in detail below in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0090] 1. Judgment basis of single / multiple primary

[0091] When registering cancer cases, cancer registries use different rules to define multiple primary cases, referring to the MULTIPLE PRIMARY NEOPLASMS criteria for multiple primary patients developed by the International Association of Cancer Registries of the World Health Organization's International Agency for Research on Cancer. The rules given here are used to report data on cancer incidence and survival so that cancer risks and outcomes are comparable between different populations. In terms of collection, it is recommended that registries collect and register more detailed data, and some suggestions are made in the following recording recommendations. This situation should be broken down to comply with international analysis rules. The rules apply to codes as ICDO3:

[0092] RULES FOR REPORTING INCIDENCE AND SURVIVAL

[0093] 1. Recognition of the presence of two or more primary cancers is independent of time

[0094] 2. Primary cancer is cancer that originates from the original site or tissue and does not extend, recur, or metastasize.

[0095] A primary cancer is one that originates in a primary site or tissueand is not an extension,nor a recurrence,nor a metastasis

[0096] 3. Only one type of tumor can occur in one organ or a pair of organs or tissues:

[0097] Some groups of codes are considered to be a single organ for the purposes of defining multiple tumours. These topography code groups are shown in Table 1.

[0098] Multifocal tumors—discrete masses that are clearly not connected to other primary cancers from the same primary site or tissue (such as the bladder)—are considered a single cancer.

[0099] 4. Except for the following cases:

[0100] (1) Systemic (or multicentric) cancers that potentially involve many different organs are counted only once in any individual. These are Kaposi's sarcoma (Group 15 in Table 2) and hematopoietic tumors (Groups 8-14 in Table 2).

[0101] (2) Tumors of different morphologies should be considered as multiple cancers (even if they are diagnosed at the same site at the same time):

[0102] If the morphologic diagnosis belonged to one of the categories in Table 2 and occurred at the same primary site, they were considered the same morphology for the purpose of counting multiple primary sites.

[0103] If the morphological diagnosis fell into two or more categories in Table 2 , even if they involved the same site, the morphology was considered different and two or more cases should be counted.

[0104] Individual tumors with multiple different histologies in Table 2 were registered as a single case using the highest numerical ICD-O morphology code (different histologies for the same morphology code).

[0105] However, if a morphology is nonspecific (groups (5), (14), and (17)), and a specific morphology is available, cases with the specific histology should be reported, and the nonspecific diagnosis should be ignored.

[0106] 5. Code List - Anatomy: The anatomy code group is considered a single location in the definitions of multiple cancers.

[0107] 6. Code List - Groups of malignancies considered histologically "distinct" for the purpose of defining multiple neoplasms.

[0108] 7. Special circumstances:

[0109] (1) Two morphologically identical tumors diagnosed in paired organs (e.g., breast) at different laterality (left and right, respectively) should be registered separately (counted as multiple primaries) unless they are stated to have arisen from a single primary tumor.

[0110] (2) In the special case of situation (1), the following organs are not considered as pairs: a) ovarian tumor (same morphology), b) nephroblastoma, c) retinoblastoma. When the above three tumors appear in multiple lateral positions, only one is registered (counted as a single tumor).

[0111] Reminder: Tumors in paired organs with completely different histology should be registered separately.

[0112] (3) Cancers occurring in any subsite of the colon (C18) and skin (C44) should be registered as multiple primary cancers.

[0113] 2. Judgment Principles

[0114] After the primary index information is updated, if the number of diagnostic package information is greater than 1, the following judgment is made: Match the anatomical classification according to each ICD-O-3 anatomical position in the diagnostic package, including:

[0115] 1. Different anatomy or morphology in multiple diagnostic packages are classified as multiple primaries;

[0116] 2. Special circumstances:

[0117] (1) Those with anatomy including C44 or C18 were classified as multiple primaries;

[0118] (2) those with multiple diagnostic packages that all showed hematopoietic system tumors in terms of morphology were classified as single;

[0119] (3) Multiple diagnostic package morphologies were all nonspecific and were classified as single.

[0120] Embodiment 1

[0121] like Figure 1-2 As shown, this embodiment provides a method for determining multiple primary tumors based on a diagnostic package, including:

[0122] S1, obtaining a case through a diagnostic information output circuit, and extracting a diagnostic package according to the case dimension, wherein the diagnostic package contains a plurality of pieces of information related to determining multiple primary tumors;

[0123] S2, determining a corresponding ICD-O-3 anatomical classification and an ICD-O-3 morphological classification based on a plurality of pieces of information related to the determination of multiple primaries of the tumor;

[0124] S3, determining the multiple primaries of the tumor based on the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification;

[0125] S4, displaying the information corresponding to the determination of the multiple primary sites of the tumor via the diagnostic information recording and displaying device.

[0126] As a preferred embodiment, the S1 includes:

[0127] S11, obtaining the case through the diagnostic information output circuit;

[0128] S12, extracting the diagnosis package according to the case dimension and confirming that there are multiple pieces of information related to the determination of multiple primary tumors in the diagnosis package.

[0129] As shown in Table 1, as a preferred embodiment, the ICD-O-3 anatomical classification of S2 includes:

[0130] Based on the first three digits of the ICD-O-3 anatomical site in the diagnosis package, ICD-O-3 anatomy is further classified into:

[0131] If the first three digits are C01 or CO2, the anatomical classification is C02.9;

[0132] If the first three digits are C00, C03, C04, C05, or CO6, the anatomical classification is C06.9;

[0133] If the first three digits are C09, C10, C12, C13, or C14, the anatomical classification is C14.0;

[0134] If the first three digits are C19 or C20, the anatomical classification is C20.9;

[0135] If the first three digits are C23 or C24, the anatomical classification is C24.9;

[0136] If the first three digits are C33 or C34, the anatomical classification is C34.9;

[0137] If the first three digits are C40 or C41, the anatomical classification is C41.9;

[0138] If the first three digits are C65, C66, C67, or C68, the anatomical classification is C68.9;

[0139] If the first three digits are C44, the anatomical classification is C44;

[0140] If the first three digits are C18, the anatomical classification is C18.

[0141] Table 1 ICD-O-3 anatomical classification table

[0142]

[0143] As shown in Table 2, as a preferred embodiment, the ICD-O-3 morphological classification of S2 includes:

[0144] The ICD-O-3 morphological classification is determined according to the ICD-O-3 morphological code in the diagnosis package, wherein the range represented by the ICD-O-3 morphological code in the diagnosis package includes all morphological codes within the range of all tumors; according to the ICD-O-3 morphological classification, systemic or multicentric tumors and unspecified tumor types can be determined; including:

[0145] If the ICD-O-3 morphology code is 8051-8084 or 8120-8131, the ICD-O-3 morphology category is 1;

[0146] If the ICD-O-3 morphology code is 8090-8110, the ICD-O-3 morphology category is 2;

[0147] If the ICD-O-3 morphology code is 8140-8149, 8160-8162, 8190-8221, 8260-8337, 8350-8551, 8570-8576, or 8940-8941, the ICD-O-3 morphology category is 3;

[0148] If the ICD-O-3 morphology code is 8030-8046, 8150-8157, 8170-8180, 8230-8255, 8340-8347, 8560-8562, or 8580-8671, the ICD-O-3 morphology category is 4;

[0149] If the ICD-O-3 morphology code is 8010-8015, 8020-8022, or 8050, the ICD-O-3 morphology category is 5;

[0150] If the ICD-O-3 morphology code is 8680-8713, 8800-8921, 8990-8991, 9040-9044, 9120-9125, 9130-9136, 9141-9252, 9370-9373, or 9540-9582, the ICD-O-3 morphology category is 6;

[0151] If the ICD-O-3 morphology code is 9050-9055, the ICD-O-3 morphology category is 7;

[0152] If the ICD-O-3 morphology code is 9840, 9861-9931, 9945-9946, 9950, 9961-9964, or 9980-9987, the ICD-O-3 morphology category is 8;

[0153] If the ICD-O-3 morphology code is 9670-9699, 9728, 9731-9734, 9761-9767, 9769, 9823-9826, 9833, 9836, or 9940, the ICD-O-3 morphology category is 9;

[0154] If the ICD-O-3 morphology code is 9700-9719, 9729, 9768, 9827-9831, 9834, 9837, or 9948, the ICD-O-3 morphology category is 10;

[0155] If the ICD-O-3 morphology code is 9650-9667, the ICD-O-3 morphology category is 11;

[0156] If the ICD-O-3 morphology code is 9740-9742, the ICD-O-3 morphology category is 12;

[0157] If the ICD-O-3 morphology code is 9750-9758, the ICD-O-3 morphology category is 13;

[0158] If the ICD-O-3 morphology code is 9590-9591, 9596, 9727, 9760, 9800-9801, 9805, 9820, 9832, 9835, 9860, 9960, 9970, 9975, or 9989, the ICD-O-3 morphology category is 14;

[0159] If the ICD-O-3 morphology code is 9140, the ICD-O-3 morphology category is 15;

[0160] If the ICD-O-3 morphology code is 8720-8790, 8930-8936, 8950-8983, 9000-9030, 9060-9110, 9260-9365, or 9380-9539, the ICD-O-3 morphology category is 16;

[0161] If the ICD-O-3 morphology code is 8000-8005, the ICD-O-3 morphology category is 17.

[0162] Table 2 ICD-O-3 morphological judgment table

[0163]

[0164]

[0165]

[0166] As a preferred implementation, S3 includes:

[0167] S31, performing a first judgment according to the ICD-O-3 anatomical classification, including:

[0168] If the ICD-O-3 anatomical classification includes C44 or C18, it is judged as multiple primary;

[0169] If the ICD-O-3 anatomical classification does not include C44 or C18, continue to judge;

[0170] S32, performing a second judgment based on the same ICD-O-3 anatomical classification, wherein the second judgment is performed based on the ICD-O-3 morphological classification, including:

[0171] If the ICD-O-3 morphological classification is the same, it is judged as single;

[0172] If the ICD-O-3 morphological classification is different, continue to judge;

[0173] S33, performing a third judgment according to the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification, including:

[0174] If the ICD-O-3 morphological classification is different and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification group 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification group 5, 14, 17, it is judged to be multiple primary;

[0175] If the ICD-O-3 morphological classification is the same and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification groups 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification 5, 14, 17, it is judged as a single tumor;

[0176] S34, performing a fourth judgment according to the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification, including:

[0177] If the ICD-O-3 morphological classification is different and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification group 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification group 5, 14, 17, it is judged to be multiple primary;

[0178] If the ICD-O-3 morphological classification is the same and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification groups 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification 5, 14, and 17, it is judged to be a single tumor.

[0179] As a preferred embodiment, the diagnostic information output circuit reads the enable signal, timing signal, reset signal, and clock signal in the control device to monitor whether a problem occurs; determines the operating status and fault status of the control device when it is started based on the information of each electrical signal; generates maintenance diagnostic information based on the judgment result, and outputs the diagnostic information to the outside as an electrical signal via the power interface of the first universal interface through the first control switch; the diagnostic information output circuit sets the power interface to the power pull-up state through the second control switch S2, thereby setting it to the signal input state, and detecting the response signal from the external diagnostic circuit; the diagnostic information output circuit reads the data pin of the first universal interface, monitors whether a normal external device other than the diagnostic information recording and display device is connected to the first universal interface, and controls the update of the patient medical record information data and the output of the modification information according to the monitoring result.

[0180] As a preferred embodiment, the diagnostic information recording and display device has a diagnostic information recording and display circuit and a second universal interface, and the diagnostic information recording and display device is connected to a control device via a cable such as a USB cable for use; the diagnostic information recording and display device is provided with a data pin connected to the second universal interface, and by detecting the data pin, the diagnostic information output circuit of the control device can determine the working status of the external device and the diagnostic information recording and display device.

[0181] As a preferred embodiment, a personal computer or a numerical control device with a display is connected to the diagnostic information recording and display circuit; the diagnostic information recording and display circuit monitors the power interface of the second universal interface, analyzes the electrical signal input through the power interface, and obtains the diagnostic information of the control device generated by the control device; the acquired diagnostic information is output to the personal computer or the numerical control device, and displayed on the display via the personal computer or the numerical control device, thereby notifying the user who extracted the patient diagnostic package information; the diagnostic information recording and display circuit generates a response signal to the diagnostic information according to the third control switch, and outputs it to the diagnostic information output circuit via the power interface of the second universal interface.

[0182] Embodiment 2

[0183] like Figure 3 As shown, this embodiment provides a system for determining multiple primary tumors based on a diagnostic package, including:

[0184] The information extraction module 101 is used to obtain the case through the diagnostic information output circuit, and extract the diagnosis package according to the case dimension, wherein the diagnosis package contains a plurality of information related to the determination of multiple primary tumors;

[0185] A classification module 102, for determining a corresponding ICD-O-3 anatomical classification and an ICD-O-3 morphological classification based on a plurality of pieces of information related to the determination of multiple primaries of a tumor;

[0186] A tumor multiple primary determination module 103, configured to determine the multiple primary locations of a tumor based on the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification;

[0187] The information display module 104 is used to display the information corresponding to the determination of multiple primary sites of the tumor through the diagnostic information recording and display device.

[0188] Application Examples

[0189] Sixteen typical cases were collected and the multiple primaries of the tumors were determined. The results are shown in Table 3 below.

[0190] Table 3 Example table

[0191]

[0192] The present invention also provides a memory storing a plurality of instructions, wherein the instructions are used to implement the method described in the first embodiment.

[0193] like Figure 4 As shown, the present invention also provides an electronic device, including a processor 301 and a memory 302 connected to the processor 301, wherein the memory 302 stores a plurality of instructions, which can be loaded and executed by the processor so that the processor can execute the method described in Example 1.

[0194] Although preferred embodiments of the present invention have been described, additional changes and modifications may be made to these embodiments by those skilled in the art once the basic inventive concepts are known. Therefore, the appended claims are intended to be interpreted as including the preferred embodiments and all changes and modifications that fall within the scope of the present invention. Obviously, those skilled in the art may make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A method for determining multiple primary tumors based on a diagnostic package, characterized in that: include: S1, obtaining a case through a diagnostic information output circuit, and extracting a diagnostic package according to the case dimension, wherein the diagnostic package contains a plurality of pieces of information related to determining multiple primary tumors; S2, determining a corresponding ICD-O-3 anatomical classification and an ICD-O-3 morphological classification based on a plurality of pieces of information related to the determination of multiple primaries of the tumor; S3, determining the multiple primaries of the tumor based on the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification; S4, displaying the information corresponding to the determination of the multiple primary sites of the tumor via the diagnostic information recording and displaying device.

2. A method for determining multiple primary tumors based on a diagnostic package according to claim 1, characterized in that: The S1 includes: S11, obtaining the case through the diagnostic information output circuit; S12, extracting the diagnosis package according to the case dimension and confirming that there are multiple pieces of information related to the determination of multiple primary tumors in the diagnosis package.

3. A method for determining multiple primary tumors based on a diagnostic package according to claim 2, characterized in that: The ICD-O-3 anatomical categories of S2 include: Based on the first three digits of the ICD-O-3 anatomical site in the diagnosis package, ICD-O-3 anatomy is further classified into: If the first three digits are C01 or CO2, the anatomical classification is C02.9; If the first three digits are C00, C03, C04, C05, or CO6, the anatomical classification is C06.9; If the first three digits are C09, C10, C12, C13, or C14, the anatomical classification is C14.0; If the first three digits are C19 or C20, the anatomical classification is C20.9; If the first three digits are C23 or C24, the anatomical classification is C24.9; If the first three digits are C33 or C34, the anatomical classification is C34.9; If the first three digits are C40 or C41, the anatomical classification is C41.9; If the first three digits are C65, C66, C67, or C68, the anatomical classification is C68.9; If the first three digits are C44, the anatomical classification is C44; If the first three digits are C18, the anatomical classification is C18.

4. A method for determining multiple primary tumors based on a diagnostic package according to claim 3, characterized in that: The ICD-O-3 morphology classification of the S2 includes: The ICD-O-3 morphological classification is determined according to the ICD-O-3 morphological code in the diagnosis package, wherein the range represented by the ICD-O-3 morphological code in the diagnosis package includes all morphological codes within the range of all tumors; according to the ICD-O-3 morphological classification, systemic or multicentric tumors and unspecified tumor types can be determined; including: If the ICD-O-3 morphology code is 8051-8084 or 8120-8131, the ICD-O-3 morphology category is 1; If the ICD-O-3 morphology code is 8090-8110, the ICD-O-3 morphology category is 2; If the ICD-O-3 morphology code is 8140-8149, 8160-8162, 8190-8221, 8260-8337, 8350-8551, 8570-8576, or 8940-8941, the ICD-O-3 morphology category is 3; If the ICD-O-3 morphology code is 8030-8046, 8150-8157, 8170-8180, 8230-8255, 8340-8347, 8560-8562, or 8580-8671, the ICD-O-3 morphology category is 4; If the ICD-O-3 morphology code is 8010-8015, 8020-8022, or 8050, the ICD-O-3 morphology category is 5; If the ICD-O-3 morphology code is 8680-8713, 8800-8921, 8990-8991, 9040-9044, 9120-9125, 9130-9136, 9141-9252, 9370-9373, or 9540-9582, the ICD-O-3 morphology category is 6; If the ICD-O-3 morphology code is 9050-9055, the ICD-O-3 morphology category is 7; If the ICD-O-3 morphology code is 9840, 9861-9931, 9945-9946, 9950, 9961-9964, or 9980-9987, the ICD-O-3 morphology category is 8; If the ICD-O-3 morphology code is 9670-9699, 9728, 9731-9734, 9761-9767, 9769, 9823-9826, 9833, 9836, or 9940, the ICD-O-3 morphology category is 9; If the ICD-O-3 morphology code is 9700-9719, 9729, 9768, 9827-9831, 9834, 9837, or 9948, the ICD-O-3 morphology category is 10; If the ICD-O-3 morphology code is 9650-9667, the ICD-O-3 morphology category is 11; If the ICD-O-3 morphology code is 9740-9742, the ICD-O-3 morphology category is 12; If the ICD-O-3 morphology code is 9750-9758, the ICD-O-3 morphology category is 13; If the ICD-O-3 morphology code is 9590-9591, 9596, 9727, 9760, 9800-9801, 9805, 9820, 9832, 9835, 9860, 9960, 9970, 9975, or 9989, the ICD-O-3 morphology category is 14; If the ICD-O-3 morphology code is 9140, the ICD-O-3 morphology category is 15; If the ICD-O-3 morphology code is 8720-8790, 8930-8936, 8950-8983, 9000-9030, 9060-9110, 9260-9365, or 9380-9539, the ICD-O-3 morphology category is 16; If the ICD-O-3 morphology code is 8000-8005, the ICD-O-3 morphology category is 17.

5. A method for determining multiple primary tumors based on a diagnostic package according to claim 4, characterized in that: The S3 includes: S31, performing a first judgment according to the ICD-O-3 anatomical classification, including: If the ICD-O-3 anatomical classification includes C44 or C18, it is judged as multiple primary; If the ICD-O-3 anatomical classification does not include C44 or C18, continue to judge; S32, performing a second judgment based on the same ICD-O-3 anatomical classification, wherein the second judgment is performed based on the ICD-O-3 morphological classification, including: If the ICD-O-3 morphological classification is the same, it is judged as single; If the ICD-O-3 morphological classification is different, continue to judge; S33, performing a third judgment according to the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification, including: If the ICD-O-3 morphological classification is different and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification group 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification group 5, 14, 17, it is judged to be multiple primary; If the ICD-O-3 morphological classification is the same and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification groups 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification 5, 14, 17, it is judged as a single tumor; S34, performing a fourth judgment according to the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification, including: If the ICD-O-3 morphological classification is different and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification group 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification group 5, 14, 17, it is judged to be multiple primary; If the ICD-O-3 morphological classification is the same and belongs to the hematopoietic system tumor corresponding to the ICD-O-3 morphological classification groups 8 to 14 or belongs to the unspecified tumor of the ICD-O-3 morphological classification 5, 14, and 17, it is judged to be a single tumor.

6. A method for determining multiple primary tumors based on a diagnostic package according to claim 5, characterized in that: The diagnostic information output circuit reads the enable signal, timing signal, reset signal, and clock signal in the control device to monitor whether a problem occurs; determines the operating status and fault status of the control device when it is started based on the information of each electrical signal; generates maintenance diagnostic information based on the judgment result, and outputs the diagnostic information to the outside as an electrical signal via the power interface of the first universal interface through the first control switch; the diagnostic information output circuit sets the power interface to the power pull-up state through the second control switch, thereby setting it to the signal input state, and detecting the response signal from the external diagnostic circuit; the diagnostic information output circuit reads the data pin of the first universal interface, monitors whether a normal external device other than the diagnostic information recording and display device is connected to the first universal interface, and controls the update of the patient medical record information data and the output of the modification information based on the monitoring result.

7. A method for determining multiple primary tumors based on a diagnostic package according to claim 6, characterized in that: The diagnostic information recording and display device is provided with a diagnostic information recording and display circuit and a second universal interface, and is connected to a control device via a USB cable for use; the diagnostic information recording and display device is provided with a data pin connected to the second universal interface, and by detecting the data pin, the diagnostic information output circuit of the control device can determine the working status of the external device and the diagnostic information recording and display device; a personal computer or a numerical control device with a display is connected to the diagnostic information recording and display circuit; the diagnostic information recording and display circuit monitors the power interface of the second universal interface, analyzes the electrical signal input via the power interface, and obtains the diagnostic information of the control device generated by the control device; the obtained diagnostic information is output to the personal computer or the numerical control device, and is displayed on the display via the personal computer or the numerical control device, thereby notifying the user who has extracted the patient diagnostic package information; the diagnostic information recording and display circuit generates a response signal for the diagnostic information according to the third control switch, and outputs it to the diagnostic information output circuit via the power interface of the second universal interface.

8. A system for determining multiple primary tumors based on a diagnostic package, used to implement the method of any one of claims 1 to 7, characterized in that: include: An information extraction module (101) is used to obtain a case through a diagnostic information output circuit, and extract a diagnostic package according to the case dimension, wherein the diagnostic package contains a plurality of pieces of information related to the determination of multiple primary tumors; A classification module (102), configured to determine a corresponding ICD-O-3 anatomical classification and an ICD-O-3 morphological classification based on a plurality of pieces of information related to the determination of multiple primaries of a tumor; A tumor multiple primary determination module (103), used for determining the multiple primary locations of tumors based on the ICD-O-3 anatomical classification and the ICD-O-3 morphological classification; An information display module (104) is used to display the information corresponding to the determination of multiple primary sites of the tumor through the diagnostic information recording and display device.

9. An electronic device, comprising a processor and a memory, wherein the memory stores a plurality of instructions, and the processor is used to read the instructions and execute the method according to any one of claims 1 to 7.

10. A computer-readable storage medium storing a plurality of instructions, wherein the plurality of instructions can be read by a processor and executed by a method according to any one of claims 1 to 7.