Repair composition as well as preparation method and application thereof
By combining the repair composition of difibrillated yeast fermentation products, yeast/zinc fermentation products and a variety of plant extracts, the problem that existing skin care products cannot completely repair the skin is solved, and the skin is fully repaired and healthy recovery is achieved, reducing allergic risks and meeting consumer needs.
Patent Information
- Application Number
- CN202510102921.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-01-22
- Publication Date
- 2025-05-02
AI Technical Summary
Although existing skin care products that repair skin can provide moisturizing, anti-inflammatory and antioxidant effects, they cannot completely repair the skin, resulting in skin susceptibility to damage and re-allergicity, and need to be used continuously, which cannot meet consumer needs.
The combination of lysate of difibrillated yeast fermentation product, yeast/zinc fermentation product, snakebed fruit extract, tea extract, chlorella extract, and aloe Curacao leaf extract is used to achieve hydration, moisturizing, anti-inflammatory, antioxidant, and promote skin barrier repair and collagen synthesis.
It has achieved comprehensive repair of the skin, completely restored health from the inside to the outside, enhanced the skin's defense ability, reduced the risk of allergies, and had a thorough repair effect to meet consumer needs.
Smart Images
Figure BDA0005254642420000071 
Figure BDA0005254642420000081
Abstract
Description
Technical Field
[0001] The invention relates to the field of skin care product raw materials, and in particular to a repair composition, a preparation method thereof and applications thereof. Background Art
[0002] As people pay more and more attention to skin health, many skin care products aimed at improving skin quality have appeared on the market. By repairing the skin and making it healthier, they can better enhance the beauty of the skin.
[0003] Existing skin repair products usually achieve moisturizing, anti-inflammatory and antioxidant effects by adding specific active ingredients, thereby helping to maintain or rebuild healthy skin conditions.
[0004] Although the skin can be restored to health through moisturizing, anti-inflammatory and antioxidant effects, the skin's lack of self-defense ability can make the skin very easy to be injured again, leading to allergies and other phenomena. As a result, products with moisturizing, anti-inflammatory and antioxidant effects need to be used continuously, which is very inconvenient and cannot repair the skin more thoroughly, making it difficult to meet the needs of consumers. Therefore, there is still room for improvement. Summary of the invention
[0005] In order to repair the skin more thoroughly, the present application provides a repair composition, a preparation method thereof, and an application thereof.
[0006] In the first aspect, the present application provides a repair composition, which adopts the following technical solution: A repair composition is a compound of a bifid yeast fermentation product lysate, a yeast / zinc fermentation product, a cnidium monnieri extract, a tea extract, a chlorella extract, and an aloe vera leaf extract.
[0007] By adopting the above technical scheme, by using a combination of bifid yeast fermentation product lysate, yeast / zinc fermentation product, cnidium monnieri extract, tea extract, chlorella extract, and aloe barbadensis leaf extract, with the cooperation of various active ingredients, it can achieve better hydrating, moisturizing, anti-inflammatory, and anti-oxidation effects, while also promoting skin barrier repair and collagen synthesis, so that the skin can be thoroughly repaired from the inside out, and the skin can be more thoroughly restored to health, so that the skin is not easily damaged again and allergies occur, thus meeting the needs of consumers well.
[0008] Preferably, the mass ratio of the bifid yeast fermentation product lysate, the yeast / zinc fermentation product, the cnidium monnieri extract, the tea extract, the chlorella extract, and the aloe vera leaf extract is 4.7-5.1:4.6-5:0.04-0.06:0.04-0.06:0.9-1.1:0.4-0.6.
[0009] By adopting the above technical scheme, by specifically selecting the mass ratios of the bifid yeast fermentation product lysate, the yeast / zinc fermentation product, the cnidium monnieri extract, the tea extract, the chlorella extract, and the aloe barbadensis leaf extract, the various active ingredients are combined in a specific ratio, thereby exerting a better synergistic effect and achieving a better skin repair effect.
[0010] Preferably, the cnidium monnieri extract, tea extract, chlorella extract, and aloe vera leaf extract are all water-soluble extracts.
[0011] By adopting the above technical solution and specifically selecting cnidium monnieri extract, tea extract, chlorella extract and aloe vera leaf extract as water-soluble extracts, the active ingredients are more easily absorbed by the skin and the effect of repairing the skin is better.
[0012] In a second aspect, the present application provides a method for preparing a repair composition, using the following technical solution: A method for preparing the above-mentioned repair composition is characterized in that it comprises the following steps: Step 1), adding cnidium monnieri extract, tea extract, chlorella extract, and aloe vera leaf extract into water, keeping the temperature at 50-55° C., and stirring evenly to obtain a composite plant extract; Step 2), concentrating and drying the plant extract to obtain a composite plant extract; Step 3), the composite plant extract, the bifid yeast fermentation product lysate, and the yeast / zinc fermentation product are mixed evenly to obtain a repair composition.
[0013] By adopting the above technical scheme, the cnidium monnieri extract, tea extract, chlorella extract and aloe vera leaf extract are put into water and stirred evenly at a constant temperature of 50-55°C, so that the active ingredients in each plant extract are better mixed, thereby better improving the synergistic effect of each component and achieving a better skin repair effect.
[0014] Preferably, in step 1), the temperature is kept at 50-55° C. and stirring is performed for 60-90 minutes.
[0015] By adopting the above technical solution and stirring at a constant temperature of 50-55° C. for 60-90 minutes, the active ingredients of the plant extracts can cooperate with each other better, and the prepared repair composition can repair the skin better.
[0016] Preferably, in step 1), the mass ratio of cnidium monnieri extract, tea extract, chlorella extract, aloe vera leaf extract and water is 0.04-0.06: 0.04-0.06: 0.9-1.1: 0.4-0.6: 2-3.
[0017] By adopting the above technical scheme, by specifically selecting the mass ratio of cnidium monnieri extract, tea extract, chlorella extract, aloe vera leaf extract and water, each plant extract can be fully dissolved in water, so that the active ingredients of each extract can cooperate with each other better, and at the same time, it can avoid excessive water consumption and energy waste during subsequent concentration and drying, and has high economic value.
[0018] In a third aspect, the present application provides an application of a repair composition, using the following technical solution: An application of the above-mentioned repair composition, wherein the repair composition is added to skin care products to prepare skin care products with repair efficacy.
[0019] By adopting the above technical scheme, the prepared skin care products with repairing effects can quickly repair the skin, and can play a good comprehensive role in moisturizing, anti-inflammatory, anti-oxidation, repairing the skin barrier, and promoting the synthesis of collagen, making the skin repair effect more thorough.
[0020] Preferably, the mass content of the repair composition in the skin care product is 10.68%-11.92%.
[0021] By adopting the above technical solution and specifically selecting the mass content of the repair composition in the skin care product, the skin care product can have a better effect in repairing the skin while effectively controlling the cost of raw materials, thus having a higher economic value and being beneficial to product promotion.
[0022] In summary, this application has the following beneficial effects: 1. Since the present application adopts a compound of bifid yeast fermentation product lysate, yeast / zinc fermentation product, cnidium monnieri extract, tea extract, chlorella extract, and aloe vera leaf extract, with the cooperation of various active ingredients, it has good hydrating, moisturizing, anti-inflammatory, and anti-oxidation effects, and can also promote skin barrier repair and collagen synthesis, so that the skin can be thoroughly repaired from the inside out, and the skin can be restored to health more thoroughly, so that the skin is not easily damaged again and allergic phenomena occur, which well meets the needs of consumers.
[0023] 2. In the present application, it is preferred to specifically select the mass ratio of bifid yeast fermentation product lysate, yeast / zinc fermentation product, cnidium monnieri extract, tea extract, chlorella extract, and aloe vera leaf extract so that various active ingredients are combined in a specific ratio to exert a better synergistic effect and a better skin repair effect.
[0024] 3. In the present application, it is preferred to add cnidium monnieri extract, tea extract, chlorella extract and aloe vera leaf extract into water and stir evenly at a constant temperature of 50-55°C so that the active ingredients in each plant extract are better mixed, thereby better improving the synergistic effect of each component and achieving a better skin repair effect. DETAILED DESCRIPTION
[0025] The present application is further described in detail below with reference to the embodiments.
[0026] Example 1 A repair composition is prepared by compounding a lysate of a bifid yeast fermentation product, a yeast / zinc fermentation product, a cnidium monnieri extract, a tea extract, a chlorella extract, and an aloe vera leaf extract.
[0027] The lysate of bifid yeast fermentation product was purchased from Angel Yeast Co., Ltd.
[0028] Yeast / zinc fermentation products were purchased from Angel Yeast Co., Ltd.
[0029] The Cnidium monnieri fruit extract was purchased from Guangzhou Shangzi, a water-soluble extract with an extraction ratio of 10:1.
[0030] Tea extract was purchased from Guangzhou Chengrong Biology, water-soluble extract, extraction ratio 10:1.
[0031] The Chlorella extract was purchased from Aiximei (Zhuhai) Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0032] Aloe barbadensis leaf extract was purchased from Bozhou Xier Chinese Herbal Medicine Co., Ltd. It is a water-soluble extract with an extraction ratio of 10:1.
[0033] The preparation method of the repair composition is as follows: Step 1), 0.04kg of cnidium monnieri extract, 0.04kg of tea extract, 0.9kg of chlorella extract, 0.4kg of aloe vera leaf extract, and 2kg of water are put into a stirring kettle, kept at a constant temperature of 50°C, a rotation speed of 60r / min, and stirred for 60min to obtain a composite plant extract.
[0034] Step 2), the plant extract is concentrated by rotary evaporation, the rotary evaporation pressure is 0.01 MPa, the rotary evaporation temperature is 60°C, after being concentrated to a paste, the paste is dried by powder spraying to obtain a composite plant extract.
[0035] Step 3), 1.02 kg of the composite plant extract, 4.7 kg of the bifida fermentation product lysate, and 4.6 kg of the yeast / zinc fermentation product are put into a stirring tank, the speed is 120 r / min, stirring for 30 minutes, and mixing evenly to obtain a repair composition.
[0036] Example 2 A repair composition is prepared by compounding a lysate of a bifid yeast fermentation product, a yeast / zinc fermentation product, a cnidium monnieri extract, a tea extract, a chlorella extract, and an aloe vera leaf extract.
[0037] The lysate of bifid yeast fermentation product was purchased from Angel Yeast Co., Ltd.
[0038] Yeast / zinc fermentation products were purchased from Angel Yeast Co., Ltd.
[0039] The Cnidium monnieri fruit extract was purchased from Guangzhou Shangzi, a water-soluble extract with an extraction ratio of 10:1.
[0040] Tea extract was purchased from Guangzhou Chengrong Biology, water-soluble extract, extraction ratio 10:1.
[0041] The Chlorella extract was purchased from Aiximei (Zhuhai) Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0042] Aloe barbadensis leaf extract was purchased from Bozhou Xier Chinese Herbal Medicine Co., Ltd. It is a water-soluble extract with an extraction ratio of 10:1.
[0043] The preparation method of the repair composition is as follows: Step 1), 0.05 kg of cnidium monnieri extract, 0.05 kg of tea extract, 1 kg of chlorella extract, 0.5 kg of aloe vera leaf extract, and 2.5 kg of water are put into a stirring kettle, kept at a constant temperature of 52.5° C., a rotation speed of 60 r / min, and stirred for 75 minutes to obtain a composite plant extract.
[0044] Step 2), the plant extract is concentrated by rotary evaporation, the rotary evaporation pressure is 0.01 MPa, the rotary evaporation temperature is 60°C, after being concentrated to a paste, the paste is dried by powder spraying to obtain a composite plant extract.
[0045] Step 3), 1.6 kg of the composite plant extract, 4.9 kg of the bifida fermentation product lysate, and 4.8 kg of the yeast / zinc fermentation product are put into a stirring tank, the speed is 120 r / min, and the stirring is carried out for 30 minutes to mix evenly to obtain a repair composition.
[0046] Example 3 A repair composition is prepared by compounding a lysate of a bifid yeast fermentation product, a yeast / zinc fermentation product, a cnidium monnieri extract, a tea extract, a chlorella extract, and an aloe vera leaf extract.
[0047] The lysate of bifid yeast fermentation product was purchased from Angel Yeast Co., Ltd.
[0048] Yeast / zinc fermentation products were purchased from Angel Yeast Co., Ltd.
[0049] The Cnidium monnieri fruit extract was purchased from Guangzhou Shangzi, a water-soluble extract with an extraction ratio of 10:1.
[0050] Tea extract was purchased from Guangzhou Chengrong Biology, water-soluble extract, extraction ratio 10:1.
[0051] The Chlorella extract was purchased from Aiximei (Zhuhai) Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0052] Aloe barbadensis leaf extract was purchased from Bozhou Xier Chinese Herbal Medicine Co., Ltd. It is a water-soluble extract with an extraction ratio of 10:1.
[0053] The preparation method of the repair composition is as follows: Step 1), 0.06 kg of cnidium monnieri extract, 0.06 kg of tea extract, 1.1 kg of chlorella extract, 0.6 kg of aloe vera leaf extract, and 3 kg of water are put into a stirring kettle, kept at a constant temperature of 55° C., a rotation speed of 60 r / min, and stirred for 90 minutes to obtain a composite plant extract.
[0054] Step 2), the plant extract is concentrated by rotary evaporation, the rotary evaporation pressure is 0.01 MPa, the rotary evaporation temperature is 60°C, after being concentrated to a paste, the paste is dried by powder spraying to obtain a composite plant extract.
[0055] Step 3), 1.82 kg of the composite plant extract, 5.1 kg of the bifid yeast fermentation product lysate, and 5 kg of the yeast / zinc fermentation product are put into a stirring tank, the speed is 120 r / min, stirring for 30 minutes, and mixing evenly to obtain a repair composition.
[0056] Comparative Example 1 A repair composition, compared with Example 2, the only difference is: The lysate of the fermentation product of Bifida was replaced by the lysate of the fermentation product of Lactobacillus in an equal amount.
[0057] The lactobacillus fermentation lysate was purchased from Shandong Huling New Materials Co., Ltd.
[0058] Comparative Example 2 A repair composition, compared with Example 2, the only difference is: The yeast / zinc fermentation product was replaced in equal amounts with the Bacillus fermentation product.
[0059] The Bacillus fermentation products were purchased from Hubei Xinyuhong Biopharmaceutical Technology Co., Ltd.
[0060] Comparative Example 3 A repair composition, compared with Example 2, the only difference is: An equal amount of liquorice extract was used to replace the cnidium monnieri extract.
[0061] Licorice extract was purchased from Shenzhen Zero One Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0062] Comparative Example 4 A repair composition, compared with Example 2, the only difference is: Replace tea extract with an equal amount of Centella asiatica extract.
[0063] Centella asiatica extract was purchased from Fufeng Ciyuan Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0064] Comparative Example 5 A repair composition, compared with Example 2, the only difference is: Replace the chlorella extract with an equal amount of rose flower extract.
[0065] Rose extract was purchased from Wuhan Huaxiang Kejie Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0066] Comparative Example 6 A repair composition, compared with Example 2, the only difference is: Replace the aloe barbadensis leaf extract with an equal amount of purslane extract.
[0067] Purslane extract was purchased from Jiangsu Weizhirun Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0068] Comparative Example 7 A repair composition, compared with Example 2, the only difference is: An equal amount of lactobacillus fermentation lysate was used to replace the bifid yeast fermentation product lysate, an equal amount of Bacillus fermentation product was used to replace the yeast / zinc fermentation product, an equal amount of licorice extract was used to replace the cnidium monnieri extract, an equal amount of Centella asiatica extract was used to replace the tea extract, an equal amount of rose flower extract was used to replace the chlorella extract, and an equal amount of purslane extract was used to replace the aloe barbadensis leaf extract.
[0069] The lactobacillus fermentation lysate was purchased from Shandong Huling New Materials Co., Ltd.
[0070] The Bacillus fermentation products were purchased from Hubei Xinyuhong Biopharmaceutical Technology Co., Ltd.
[0071] Licorice extract was purchased from Shenzhen Zero One Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0072] Centella asiatica extract was purchased from Fufeng Ciyuan Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0073] Rose extract was purchased from Wuhan Huaxiang Kejie Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0074] Purslane extract was purchased from Jiangsu Weizhirun Biotechnology Co., Ltd., a water-soluble extract with an extraction ratio of 10:1.
[0075] Experiment 1 According to T / SHRH 006-2018 "Experimental Method for Scavenging Cosmetics Free Radicals (DPPH)", the DPPH free radical scavenging rate (%) of the test sample prepared by the repair composition of each embodiment and comparative example was detected.
[0076] Preparation of the sample to be tested: Take 11 g of the repair composition and 89 g of deionized water, mix them evenly until they are completely dissolved, and obtain the sample to be tested.
[0077] Experiment 2 A number of volunteers, aged 30-40 years old, female, were recruited, with 10 volunteers in each group. They were divided into groups and used the test samples prepared from the repair compositions of the embodiments and comparative examples for 15 consecutive days, once in the morning and once in the evening every day. Before use, they cleaned their faces with clean water and disposable face washcloths, wiped off the water, and then took 3 ml of the test sample and evenly applied it on the face. No other skin care products were used during the experiment.
[0078] Preparation of the sample to be tested: Take 11 g of the repair composition and 89 g of deionized water, mix them evenly until they are completely dissolved, and obtain the sample to be tested.
[0079] The moisture content, transepidermal water loss rate and skin elasticity value of the skin were tested before starting to use the test samples and 15 days after using the test samples.
[0080] The testing time before starting to use the test samples is to use a disposable face washcloth with clean water and then move freely for 12 hours, and then the test is carried out. During the free time, do not clean your face, use the test samples, or use any skin care products.
[0081] The testing time after using the test samples for 15 days is the morning of the 16th day, and the time interval between using the test samples on the evening of the 15th day is 12 hours. From the use of the test samples on the evening of the 15th day to the testing on the 16th day, do not clean your face, use the test samples, or use any skin care products.
[0082] Moisture content detection: Use the skin moisture content Corneometer test probe to test the cheeks.
[0083] Transepidermal water loss TEWL test: The multi-probe skin testing system CK-Tewameter TM Hex was used to test the cheeks.
[0084] Skin elasticity test: The skin elasticity Cotometer MPA580 host manufactured by Courage+Khazaka of Germany was used, and the probe was the Reviscometer RV600 elastic fiber tissue test probe.
[0085] R2=Ua / Uf, R5=Ur / Ue, R7=Ur / Uf; Uf: maximum stretch of skin; Ua: The recovery value of the skin from the time when negative pressure is removed to the time when negative pressure is applied to the skin surface again during the next continuous test; Ue: The stretching amount of the skin at 0.1 second after constant negative pressure is applied to the skin, and the stretching amount of the positioning elastic part; Ur: The recovery value and viscoelastic value of the skin, or the plastic value, 0.1s after the negative pressure is removed.
[0086] The experimental data of each group were averaged.
[0087] The specific test data of Experiment 1-2 are shown in Table 1-2.
[0088] Table 1 Table 2 Initial R2 15dR2 Initial R5 15dR5 Initial R7 15dR7 Example 1 0.5758 0.9397 0.5185 0.8904 0.4437 0.7725 Example 2 0.5712 0.9408 0.5143 0.8874 0.4499 0.7869 Example 3 0.5767 0.9487 0.5197 0.8947 0.4428 0.7727 Comparative Example 1 0.5744 0.7964 0.5126 0.7671 0.4446 0.6820 Comparative Example 2 0.5697 0.7963 0.5234 0.7931 0.4471 0.6890 Comparative Example 3 0.5727 0.7821 0.5139 0.7724 0.4394 0.6762 Comparative Example 4 0.5688 0.8034 0.5148 0.7768 0.4431 0.6833 Comparative Example 5 0.5794 0.7976 0.5212 0.7782 0.4417 0.6776 Comparative Example 6 0.5691 0.7861 0.5207 0.7873 0.4486 0.6926 Comparative Example 7 0.5739 0.7722 0.5181 0.7591 0.4457 0.6824 According to the data comparison of each embodiment and comparative example in Table 1-2, the free radical scavenging performance of each embodiment and comparative example is similar, which shows that each embodiment and comparative example has good antioxidant effect, and the degree of improvement of skin moisture content at 15 days in each embodiment and comparative example is similar, which shows that each embodiment and comparative example has good moisturizing effect.
[0089] The 15d transepidermal water loss rate of each embodiment is significantly lower than that of each comparative example. It can be seen that each embodiment repairs the skin barrier very well, and its effect of repairing the skin barrier is significantly better than that of each comparative example.
[0090] The improvement degree of 15dR2, 15dR5 and 15dR7 in each embodiment is significantly higher than that in each comparative example. It can be seen that each embodiment promotes the synthesis of skin collagen, thereby restoring the elasticity of the skin, and its effect of restoring the elasticity of the skin is significantly higher than that in each comparative example.
[0091] It can be seen that the embodiments can play a good role in moisturizing, anti-oxidation, repairing the skin barrier, promoting collagen synthesis, etc. through the special combination of bifid yeast fermentation product lysate, yeast / zinc fermentation product, cnidium monnieri extract, tea extract, chlorella extract, and aloe vera leaf extract. It can repair the skin through multi-faceted synergistic repair, so that the skin can be restored to health more thoroughly. The effect of repairing the skin in each embodiment is significantly better than that in each comparative example.
[0092] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make modifications to the present embodiment without any creative contribution as needed, but such modifications are protected by the patent law as long as they are within the scope of the claims of the present application.
Claims
1. A repair composition, characterized in that: The repair composition is a compound of bifid yeast fermentation product lysate, yeast / zinc fermentation product, cnidium monnieri extract, tea extract, chlorella extract, and aloe vera leaf extract.
2. A repair composition according to claim 1, characterized in that: The mass ratio of the bifid yeast fermentation product lysate, the yeast / zinc fermentation product, the cnidium monnieri extract, the tea extract, the chlorella extract and the aloe vera leaf extract is 4.7-5.1:4.6-5:0.04-0.06:0.04-0.06:0.9-1.1:0.4-0.
6.
3. A repair composition according to claim 2, characterized in that: The cnidium monnieri extract, tea extract, chlorella extract and aloe vera leaf extract are all water-soluble extracts.
4. A method for preparing the repair composition according to any one of claims 1 to 3, characterized in that: The following steps are involved: Step 1), add cnidium monnieri extract, tea extract, chlorella extract, and aloe vera leaf extract into water, keep the temperature at 50-55°C, and stir evenly to obtain a composite plant extract; Step 2), concentrating and drying the plant extract to obtain a composite plant extract; Step 3) Evenly mix the composite plant extract, the bifid yeast fermentation product lysate, and the yeast / zinc fermentation product to obtain a repair composition.
5. The method for preparing a repair composition according to claim 4, characterized in that: In the step 1), the temperature is kept at 50-55° C. and the mixture is stirred for 60-90 minutes.
6. The method for preparing a repair composition according to claim 5, characterized in that: In the step 1), the mass ratio of cnidium monnieri extract, tea extract, chlorella extract, aloe vera leaf extract and water is 0.04-0.06: 0.04-0.06: 0.9-1.1: 0.4-0.6: 2-3.
7. An application of the repair composition according to any one of claims 1 to 3, characterized in that: The repairing composition is added into skin care products to prepare skin care products with repairing effects.
8. The use of a repair composition according to claim 7, characterized in that: The mass content of the repair composition in the skin care product is 10.68%-11.92%.