Mouthwash liquid medicine for treating oral inflammation and preparation method thereof

By developing a mouthwash liquid composed of Duhuo, Scutellaria baicalensis, Chuanxiong, Angelica sinensis, Asarum, Clove and Clove, the problem of difficult to adhere to the existing traditional Chinese medicine treatment methods for oral inflammation has been solved, and more convenient and effective treatment effects have been achieved.

CN119909111APending Publication Date: 2025-05-02NANJING BENQ HOSPITAL CO LTD
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Patent Information

Application Number
CN202411838653.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-13
Publication Date
2025-05-02

AI Technical Summary

Technical Problem

The existing traditional Chinese medicine treatment methods for oral inflammation are mainly through oral Chinese medicine decoctions, which makes it difficult for patients to persist in long-term use, which affects the treatment effect.

Method used

It provides a mouthwashing solution for treating oral inflammation. Its active ingredients are composed of Duhuo, Scutellaria baicalensis, Chuanxiong, Angelica sinensis, Asarum, Clove and Clove, and are made by specific weight ratios and preparation methods. This mouth-washing liquid does not require oral administration. It is convenient and easy to persist for a long time through mouth rinsing.

Benefits of technology

This mouthwash liquid can effectively reduce oral inflammation, especially periodontitis, gingivitis and pulpitis. Its use method is simple, which is conducive to patients' long-term persistence, thereby achieving better anti-inflammatory effects.

✦ Generated by Eureka AI based on patent content.
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Abstract

The invention provides a mouthwash liquid for treating oral inflammation and a preparation method thereof. The mouthwash liquid comprises the following active ingredients: radix angelicae pubescentis, scutellaria baicalensis, ligusticum wallichii, angelica sinensis, asarum, long pepper and clove. The traditional Chinese medicine composition comprises the following effective components in parts by weight: 3-6 parts of radix angelicae pubescentis, 3-6 parts of scutellaria baicalensis, 3-6 parts of ligusticum wallichii, 3-6 parts of angelica sinensis, 1-3 parts of asarum, 1-3 parts of long pepper and 1-3 parts of clove. By means of the active ingredient, oral inflammation of a patient can be effectively treated. The gargling liquid medicine is more convenient to use and beneficial to long-term persistence of patients, so that a better treatment effect is achieved.
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Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a mouthwash liquid for treating oral inflammation and a preparation method thereof. Background Art

[0002] Oral inflammations such as periodontitis and gingivitis are common oral diseases. At present, the use of traditional Chinese medicine to treat these oral inflammations is generally through oral Chinese medicine, which requires patients to boil Chinese medicine decoctions and take them orally for a long time. It is difficult for patients to persist, thus affecting the treatment effect.

[0003] Therefore, how to prepare a traditional Chinese medicine for treating oral inflammation that is easy to use and conducive to patient adherence while ensuring the therapeutic effect has become a new research topic. Summary of the invention

[0004] The present invention aims to effectively treat oral inflammation in patients.

[0005] To achieve the above object, the present invention provides a mouthwash for treating oral inflammation, wherein the effective ingredients of the mouthwash are composed of Angelica dahurica, Scutellaria baicalensis, Ligusticum chuanxiong, Angelica sinensis, Asarum, Piper longum and Clove; Among them, the effective ingredients and their weight ratios are: 3-6 weight parts of Angelica dahurica, 3-6 weight parts of Scutellaria baicalensis, 3-6 weight parts of Ligusticum chuanxiong, 3-6 weight parts of Angelica sinensis, 1-3 weight parts of Asarum, 1-3 weight parts of Piper longum, and 1-3 weight parts of Clove.

[0006] Preferably, the effective ingredients and their weight ratios are: 3 parts by weight of Angelica dahurica, 3 parts by weight of Scutellaria baicalensis, 3 parts by weight of Rhizoma Chuanxiong, 3 parts by weight of Angelica sinensis, 1 part by weight of Asarum, 1 part by weight of Piper longum, and 1 part by weight of Clove.

[0007] Preferably, the oral inflammation includes periodontitis, gingivitis and pulpitis.

[0008] To achieve the above object, the present invention also provides a method for preparing a mouthwash liquid for treating oral inflammation, comprising: Step S1, weighing the active ingredient according to the weight ratio, the total weight of the active ingredient is 250-350g; Step S2, adding 900-1000 ml of water to the effective ingredient, soaking it, boiling it with high heat, and then decocting it with low heat for 90-100 minutes, filtering it to obtain a first filter residue and 180-220 ml of a first filtrate; Step S3, adding 250-350 ml of water to the first filter residue, boiling over high heat, and then simmering over low heat for 30-40 minutes, filtering to obtain 80-120 ml of the second filtrate; Step S4: After the first filtrate is mixed with the second filtrate, the mouthwash liquid is obtained.

[0009] Preferably, step S1 further comprises: after weighing the active ingredient, removing impurities from the active ingredient and drying it in the sun.

[0010] Preferably, in step S1, the total weight of the active ingredient is 300 g.

[0011] Preferably, in step S2, the active ingredient is soaked in water for 5 to 6 hours.

[0012] Preferably, in step S3, 300 ml of water is added to the filter residue.

[0013] Preferably, in step S2, the first filtrate obtained is 200 ml; and, in step S3, the second filtrate obtained is 100 ml.

[0014] Preferably, in step S4, the mouthwash liquid is also packaged and sealed, wherein each portion of the mouthwash liquid is 5 to 20 ml.

[0015] Compared with the prior art, the present invention provides a mouthwash for treating oral inflammation and a preparation method thereof, wherein the effective ingredients of the mouthwash are composed of radix angelicae pubescens, radix scutellariae, rhizoma chuanxiong, rhizoma angelicae sinensis, rhizoma asarum, rhizoma longipi and clove. The effective ingredients and weight proportions are respectively: 3-6 parts by weight of radix angelicae pubescens, 3-6 parts by weight of radix scutellariae, 3-6 parts by weight of rhizoma chuanxiong, 3-6 parts by weight of rhizoma angelicae sinensis, 1-3 parts by weight of rhizoma asarum, 1-3 parts by weight of rhizoma longipi and 1-3 parts by weight of clove. With the effective ingredients, oral inflammation of patients can be effectively treated. The mouthwash is more convenient to use, which is conducive to the long-term adherence of patients, thereby achieving a better anti-inflammatory effect. DETAILED DESCRIPTION

[0016] The present invention is further described in detail below in conjunction with specific examples. It should be understood that these examples are used to illustrate the basic principles, main features and advantages of the present invention, and the present invention is not limited to the following examples. The implementation conditions adopted in the examples can be further adjusted according to specific requirements, and the unspecified implementation conditions are usually the conditions in routine experiments. The "including" mentioned in the entire specification and claims is an open-ended term, so it should be interpreted as "including but not limited to".

[0017] In the embodiment of the present invention, each active ingredient is mixed into a matrix in a corresponding weight ratio to form a paste-like medicine. Each active ingredient and its corresponding weight ratio mainly reflect: efficacy and material cost. Only through a large number of experiments can we know which active ingredient and its weight ratio have ideal efficacy and relatively low cost.

[0018] The effective ingredients of the mouthwash for treating oral inflammation provided by the present invention are composed of Angelica dahurica, Radix Scutellariae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Radix Asarum, Rhizoma Piper and Clove. The mouthwash has the effects of clearing away heat and expelling wind, strengthening teeth and relieving pain, and can effectively reduce oral inflammation. Preferably, the oral inflammation includes periodontitis, gingivitis and pulpitis. Among them, the use method of the mouthwash is: contain about 5 to 20 ml of the mouthwash, soak the gums on each side, and continuously gargle the mouth with the medicine, and spit out the mouthwash after gargling for 3 to 15 minutes each time. In other words, the mouthwash does not need to be taken orally, and its medicine is easier to preserve than oral drugs. The use method is simple and convenient, which is conducive to long-term adherence by patients, thereby achieving a better anti-inflammatory effect. It should be noted that any of the medicinal materials in the above-mentioned effective ingredients are common medicinal materials that can be purchased on the market, and these medicinal materials have been included in medical insurance. The use of these medicinal materials can also reduce the patient's medication costs.

[0019] The pharmacology and effects of each active ingredient will be described in detail below.

[0020] Duhuo: slightly warm in nature, pungent and bitter in taste. It enters the kidney and bladder meridians, can dispel wind and dampness, relieve numbness and relieve pain, and can be used to treat wind-cold-dampness arthralgia, waist and knee pain, Shaoyin hidden wind headache, wind-cold-damp headache, skin itching, etc.

[0021] Scutellaria baicalensis: cold in nature, bitter in taste. Enters the lung, gallbladder, spleen, large intestine, and small intestine meridians. It can clear away heat and dampness, purge fire and detoxify, stop bleeding, and stabilize the fetus. It can be used to treat damp-heat, chest tightness and nausea due to summer heat, damp-heat fullness, diarrhea, jaundice, lung heat cough, high fever and thirst, blood heat vomiting and bleeding, carbuncle, sore, and fetal movement disorder.

[0022] Chuanxiong: warm in nature, pungent in taste. Enters the liver, gallbladder, and pericardium meridians. It has the effects of promoting blood circulation, removing blood stasis, dispelling wind and relieving pain, and can relieve pain. The volatile oil components in Chuanxiong have a certain inhibitory effect on brain activity, prevent the body from being overexcited, and have a sedative effect. It can be used to treat wind-cold headaches and dizziness, flank pain and abdominal pain, cold arthralgia and muscle spasms, amenorrhea, dystocia, postpartum blood stasis and pain, carbuncle, ulcer, irregular menstruation, amenorrhea and dysmenorrhea, abdominal pain due to lumps, stabbing pain in the chest and flanks, swelling and pain due to falls, headaches, rheumatic pain, etc.

[0023] Angelica: warm in nature, sweet and pungent in taste. Enters the liver, heart and spleen meridians. It has the effects of nourishing blood and activating blood circulation, regulating menstruation and relieving pain, and moistening the intestines and relieving constipation. It can be used to treat blood deficiency and sallow complexion, dizziness and palpitations, irregular menstruation, amenorrhea and dysmenorrhea, abdominal pain due to deficiency and cold, dry intestines and constipation, rheumatic arthralgia, injuries from falls, carbuncle and ulcers, etc.

[0024] Asarum: warm in nature, pungent in taste. It enters the heart, lung and kidney meridians. It has the effects of dispelling wind and cold, clearing the orifices and relieving pain, warming the lungs and transforming fluid. It can be used to treat colds, headaches, toothaches, nasal congestion and sinusitis, rheumatic pain, phlegm and cough, etc.

[0025] Piper longum: hot in nature, pungent in taste. It enters the spleen, stomach, large intestine, lung, bladder, liver, and kidney meridians. It has the effects of warming the middle and dispelling cold, lowering qi and relieving pain. It can be used to treat cold pain in the stomach and abdomen, vomiting, diarrhea, cold cold, cold hernia and abdominal pain, etc.

[0026] Clove: warm in nature, pungent in taste. Enters the spleen, stomach, and kidney meridians. It has the effects of warming the middle and lowering adverse reactions, dispelling cold and relieving pain, warming the kidney and supporting yang. It can be used to treat stomach cold vomiting, hiccups, cold pain in the abdomen, kidney deficiency, impotence, and cold uterus.

[0027] The effective ingredients and weight ratios in the mouthwash for treating oral inflammation are: 3-6 weight parts of Angelica dahurica, 3-6 weight parts of Scutellaria baicalensis, 3-6 weight parts of Ligusticum chuanxiong, 3-6 weight parts of Angelica sinensis, 1-3 weight parts of Asarum, 1-3 weight parts of Piper longum, and 1-3 weight parts of Clove. It should be noted that the weight parts represent the weight ratios of the effective ingredients and the matrix to the total weight of the ointment, that is, 1 weight part can be any weight such as 1g, 10g, 20g, etc. The specific value of 1 weight part depends on the total amount of the ointment to be configured, and the present invention is not limited thereto.

[0028] Based on the above, the preparation method of the mouthwash liquid for treating oral inflammation is to weigh each effective ingredient according to the weight ratio, and add water to boil to obtain the liquid. Specifically, the preparation method comprises the following steps: Step S1, weighing: weighing angelica dahurica, scutellaria baicalensis, ligusticum chuanxiong, angelica sinensis, asarum, longipi and clove respectively according to the weight ratio, and the total weight of these active ingredients is 250-350g; Step S2, preparing the first filtrate: adding 900-1000 ml of water to the effective ingredients weighed in step S1, soaking and then boiling with high heat, and then decocting with low heat for 90-100 minutes, filtering to obtain a first filter residue and 180-220 ml of the first filtrate; Step S3, preparing a second filtrate: adding 250-350 ml of water to the first filter residue, boiling over high heat, and then simmering over low heat for 30-40 minutes, and filtering to obtain 80-120 ml of a second filtrate; Step S4, obtaining a mouthwash solution: mixing the first filtrate obtained in step S2 with the second filtrate obtained in step S3 to obtain the mouthwash solution for treating oral inflammation.

[0029] Among them, the high fire refers to a larger and stronger firepower, and the low fire refers to a smaller and more stable firepower, which can be well known to technical personnel and will not be elaborated here.

[0030] Preferably, step S1 further includes: after weighing all the active ingredients, removing impurities from the active ingredients and drying them in the sun. The removal of impurities may include, for example, selecting the medicines, removing moldy or spoiled medicines, and washing to remove impurities, etc. The present invention is not limited thereto.

[0031] Preferably, the total weight of the active ingredient weighed in step S1 is 300 g.

[0032] Preferably, in step S2, the active ingredient is soaked in water for 5 to 6 hours to ensure that the ingredients in the medicine can be fully dissolved into the medicine solution during the decoction process.

[0033] Preferably, in step S3, 300 ml of water is added to the filter residue.

[0034] Preferably, in step S2, the first filtrate obtained is 200 ml; and, in step S3, the second filtrate obtained is 100 ml.

[0035] It should be noted that the weight of the effective ingredients, the amount of water added, the decoction time, etc. of the preparation method of the mouthwash described in this article are all values ​​given based on the amount of medicine required for a treatment cycle. In other words, when the mouthwash is actually prepared, the above values ​​can be adjusted as appropriate according to the actual condition of the patient, and the proportional changes of these values ​​should be understood as this preparation method.

[0036] Preferably, in step S4, the mouthwash liquid can also be packaged and sealed in a sterile glass bottle for standby use. Each portion of the mouthwash liquid is 5 to 20 ml, so as to help the patient control the amount of each mouthwash liquid. Further, it is preferred to rinse the mouth three times a day until the clinical symptoms and signs disappear completely. The treatment cycle is generally about two weeks, and the dosage of the mouthwash liquid can usually be increased at the beginning of the treatment course, but the actual application is not limited to this.

[0037] Among them, since the mouthwash liquid for treating oral inflammation does not need to be taken orally, it is easier to store than oral dosage forms. Patients can prepare or purchase the required dose for the entire treatment cycle at one time, and the mouthwash method is more convenient, which is conducive to patients' persistence in using it to obtain better therapeutic effects. Using the mouthwash liquid for treating oral inflammation, 100 cases were treated within 3 years, and the effectiveness rate was 100%. Among the 100 medical records, 90 cases took effect within 2 weeks of use, 4 cases took effect within 3 weeks of use; and 30 cases were cured within 2 months.

[0038] It should be noted that after taking oral dosage forms of drugs, the patient's liver needs to decompose and absorb them, which will inevitably put a burden on the patient's body. However, the mouthwash provided by the embodiment of the present invention does not need to be taken orally, and on the basis of ensuring the efficacy of the drug, it can also avoid unnecessary burden on the patient's liver.

[0039] The following is a combination of several typical clinical experimental data to illustrate the effect of the mouthwash solution for treating oral inflammation: Example

[0040] Niu, female, 16 years old, from Hongze District, Huai'an City, Jiangsu Province.

[0041] The patient visited the hospital in June 2023. He had toothache for 2 months and was diagnosed with gingivitis. He rinsed his mouth with 5-20 ml of mouthwash solution A prepared by the above-mentioned active ingredient and preparation method, 2-3 times a day. The toothache was relieved after 1 week. After another 2 weeks of use, the toothache disappeared.

[0042] In this embodiment, the weight ratio of the effective ingredients in the mouthwash solution A is specifically: 3 parts of Angelica dahurica, 3 parts of Scutellaria baicalensis, 3 parts of Ligusticum chuanxiong, 3 parts of Angelica sinensis, 1 part of Asarum, 1 part of Piper longum, and 1 part of Clove. Example

[0043] Li, female, 37 years old, from Rudong County, Nantong City, Jiangsu Province.

[0044] In November 2022, the patient had toothache for 1 month and was diagnosed with periodontitis. The patient rinsed his mouth with 5-20 ml of mouthwash solution A prepared by the above-mentioned active ingredient and preparation method, 2-3 times a day. The toothache was relieved after 5 days. After another 2 weeks of use, the toothache disappeared.

[0045] In this embodiment, the weight ratio of the active ingredients in the mouthwash solution A is the same as that in Example 1 and will not be described in detail. Example

[0046] Liu, female, 34 years old, from Yuhuatai District, Nanjing City, Jiangsu Province.

[0047] The patient visited the hospital in July 2023 and had toothache for 1 month. He was diagnosed with pulpitis. He rinsed his mouth with 5-20 ml of mouthwash solution A prepared by the above-mentioned active ingredient and preparation method, 2-3 times a day. The toothache was relieved after 1 week. After another week of use, the toothache disappeared.

[0048] In this embodiment, the weight ratio of the active ingredients in the mouthwash solution A is the same as that in Example 1 and will not be described in detail. Example

[0049] Yao, male, 37 years old, from Baixia District, Nanjing City, Jiangsu Province.

[0050] In December 2023, the patient had toothache for 1 week and was diagnosed with periodontitis. The patient rinsed his mouth with 5-20 ml of mouthwash solution A prepared by the above-mentioned active ingredient and preparation method, 2-3 times a day. The toothache was relieved after 3 days. After another week of use, the toothache disappeared.

[0051] In this embodiment, the weight ratio of the active ingredients in the mouthwash solution A is the same as that in Example 1 and will not be described in detail. Example

[0052] Ding, male, 7 years old, from Baixia District, Nanjing City, Jiangsu Province.

[0053] In October 2023, the patient had toothache for 2 days and was diagnosed with gingivitis. The patient rinsed his mouth with 5-20 ml of mouthwash solution A prepared by the above-mentioned active ingredient and preparation method, 2-3 times a day. The toothache was relieved after 3 days. After another week of use, the toothache disappeared.

[0054] In this embodiment, the weight ratio of the active ingredients in the mouthwash solution A is the same as that in Example 1 and will not be described in detail. Example

[0055] Kuang, male, 40 years old, from Jiangning District, Nanjing City, Jiangsu Province.

[0056] In August 2022, the patient had toothache for 7 days and was diagnosed with pulpitis. The patient was treated with mouthwash solution B prepared by the above-mentioned active ingredient and preparation method, 5-20 ml each time, 2-3 times a day. The toothache did not ease after 2 weeks. After another 2 weeks, the toothache eased.

[0057] In this embodiment, the weight ratio of the effective ingredients in the mouthwash solution B is specifically: 3 parts of Angelica dahurica, 3 parts of Scutellaria baicalensis, 5 parts of Ligusticum chuanxiong, 3 parts of Angelica sinensis, 1 part of Asarum, 3 parts of Piper longum, and 1 part of Clove. Example

[0058] Ao, female, 60 years old, from Yuhuatai District, Nanjing City, Jiangsu Province.

[0059] In October 2022, the patient had toothache for 1 month and was diagnosed with gingivitis. The patient rinsed his mouth with 5-20 ml of mouthwash solution C prepared by the above-mentioned active ingredient and preparation method, 2-3 times a day. The toothache did not subside after 2 weeks. After another 3 weeks, the toothache subsided.

[0060] In this embodiment, the weight ratio of the effective ingredients in the mouthwash solution C is specifically: 3 parts of Angelica dahurica, 3 parts of Scutellaria baicalensis, 4 parts of Ligusticum chuanxiong, 3 parts of Angelica sinensis, 1 part of Asarum, 1 part of Piper longum, and 3 parts of Clove. Example

[0061] Yang, female, 37 years old, from Jianye District, Nanjing City, Jiangsu Province.

[0062] The patient visited the hospital in January 2021. He had toothache for 15 days and was diagnosed with pulpitis. He rinsed his mouth with 5-20 ml of mouthwash solution D prepared by the above-mentioned active ingredient and preparation method, 2-3 times a day. The toothache did not subside after 2 weeks. After another week of use, the toothache subsided.

[0063] In this embodiment, the weight ratio of the effective ingredients in the mouthwash solution D is specifically: 5 parts of Angelica dahurica, 3 parts of Scutellaria baicalensis, 6 parts of Ligusticum chuanxiong, 3 parts of Angelica sinensis, 1 part of Asarum, 3 parts of Piper longum, and 1 part of Clove.

[0064] Li, female, 18 years old, from Jiawang District, Xuzhou City, Jiangsu Province.

[0065] In November 2023, the patient had toothache for 3 days and was diagnosed with periodontitis. The patient was treated with mouthwash solution E prepared by the above-mentioned active ingredient and preparation method, 5-20 ml each time, 2-3 times a day. After 2 weeks, the toothache did not ease, and after another 2 weeks, the toothache still did not ease, and the treatment was ineffective.

[0066] In this embodiment, the weight ratio of the effective ingredients in the mouthwash solution E is specifically: 5 parts of Angelica dahurica, 3 parts of Scutellaria baicalensis, 3 parts of Ligusticum chuanxiong, 2 parts of Angelica sinensis, 1 part of Asarum, 1 part of Piper longum, and 1 part of Clove.

[0067] Han, female, 45 years old, from Jiangning District, Nanjing.

[0068] In September 2022, the patient had toothache for 3 days and was diagnosed with gingivitis. The patient was treated with mouthwash solution F prepared by the above-mentioned active ingredient and preparation method, 5-20 ml each time, 2-3 times a day. After 2 weeks, the toothache did not ease, and after another 2 weeks, the toothache still did not ease, and the treatment was ineffective.

[0069] In this embodiment, the weight ratio of the effective ingredients in the mouthwash solution F is specifically: 3 parts of Angelica dahurica, 5 parts of Scutellaria baicalensis, 3 parts of Ligusticum chuanxiong, 2 parts of Angelica sinensis, 1 part of Asarum, 1 part of Piper longum, and 2 parts of Clove.

[0070] Cen, female, 28 years old, from Jianye District, Nanjing City, Jiangsu Province.

[0071] In August 2023, the patient had toothache for 4 days and was diagnosed with pulpitis. The patient was treated with mouthwash solution G prepared by the above-mentioned active ingredient and preparation method, 5-20 ml each time, 2-3 times a day. After 2 weeks, the toothache did not ease, and after another 2 weeks, the toothache still did not ease, and the treatment was ineffective.

[0072] In this embodiment, the weight ratio of the effective ingredients in the mouthwash solution G is specifically: 3 parts of Angelica dahurica, 3 parts of Scutellaria baicalensis, 2 parts of Ligusticum chuanxiong, 3 parts of Angelica sinensis, 1 part of Asarum, 1 part of Piper longum, and 1 part of Clove.

[0073] Ai, female, 35 years old, from Liuhe District, Nanjing.

[0074] In September 2023, the patient had toothache for 5 days and was diagnosed with periodontitis. The patient was treated with mouthwash solution H prepared by the above-mentioned active ingredient and preparation method, 5-20 ml each time, 2-3 times a day. After 2 weeks, the toothache did not ease, and after another 2 weeks, the toothache still did not ease, and the treatment was ineffective.

[0075] In this embodiment, the weight ratio of the effective ingredients in the mouthwash solution H is specifically: 3 parts of Angelica dahurica, 2 parts of Scutellaria baicalensis, 3 parts of Ligusticum chuanxiong, 3 parts of Angelica sinensis, 1 part of Asarum, 1 part of Piper longum, and 1 part of Clove.

[0076] Zhao, male, 35 years old, from Gulou District, Nanjing.

[0077] In December 2023, the patient had toothache for 7 days and was diagnosed with pulpitis. The patient was treated with the mouthwash solution I prepared by the above-mentioned active ingredient and preparation method, 5-20 ml each time, 2-3 times a day. After 2 weeks, the toothache was not relieved, and after another 2 weeks, the toothache was still not relieved, and the treatment was ineffective.

[0078] In this embodiment, the weight ratio of the effective ingredients in the mouthwash solution I is specifically: 3 parts of Angelica dahurica, 3 parts of Scutellaria baicalensis, 3 parts of Ligusticum chuanxiong, 3 parts of Angelica sinensis, 1 part of Asarum, 1 part of Piper longum, and 0.5 part of Clove. It can be seen from the above examples and comparative examples that the present invention adopts the above-mentioned active ingredients and matrix, and mixes them in a suitable mass ratio to prepare the mouthwash solutions A to D for treating oral inflammation, so that each active ingredient and matrix can produce a synergistic effect, thereby enabling the mouthwash solution to effectively treat the patient's oral inflammation. Among them, it can be seen from the length of time it takes for the patient to recover after treatment with mouthwash solutions of different ratios that mouthwash solution A has the best efficacy.

[0079] In summary, the present invention provides a mouthwash for treating oral inflammation and a preparation method thereof, wherein the effective ingredients of the mouthwash are composed of Radix Angelicae Pubescentis, Radix Scutellariae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Radix Asarum, Radix Piper and Clove. The effective ingredients and weight proportions are respectively: 3-6 parts by weight of Radix Angelicae Pubescentis, 3-6 parts by weight of Radix Scutellariae, 3-6 parts by weight of Rhizoma Chuanxiong, 3-6 parts by weight of Radix Angelicae Sinensis, 1-3 parts by weight of Radix Asarum, 1-3 parts by weight of Radix Piper and 1-3 parts by weight of Clove. With the effective ingredients, oral inflammation of patients can be effectively treated. The mouthwash is more convenient to use, which is conducive to the long-term adherence of patients, thereby achieving a better therapeutic effect.

[0080] The present invention has been described by the above-mentioned relevant embodiments, however, the above-mentioned embodiments are only examples for implementing the present invention. It must be pointed out that the disclosed embodiments do not limit the scope of the present invention. On the contrary, changes and modifications made without departing from the spirit and scope of the present invention are all within the scope of patent protection of the present invention.

Claims

1. A mouthwash for treating oral inflammation, characterized in that: The active ingredients of the mouthwash liquid are composed of angelica dahurica, scutellaria baicalensis, chuanxiong, angelica sinensis, asarum, longipi and clove. Among them, the effective ingredients and their weight ratios are: 3-6 weight parts of Angelica dahurica, 3-6 weight parts of Scutellaria baicalensis, 3-6 weight parts of Ligusticum chuanxiong, 3-6 weight parts of Angelica sinensis, 1-3 weight parts of Asarum, 1-3 weight parts of Piper longum, and 1-3 weight parts of Clove.

2. The mouthwash for treating oral inflammation according to claim 1, characterized in that: The effective ingredients and their weight proportions are: 3 parts by weight of Angelica dahurica, 3 parts by weight of Scutellaria baicalensis, 3 parts by weight of Rhizoma Chuanxiong, 3 parts by weight of Angelica sinensis, 1 part by weight of Asarum, 1 part by weight of Piper longum and 1 part by weight of Clove.

3. The mouthwash liquid for treating oral inflammation according to claim 1, characterized in that: The oral inflammation includes periodontitis, gingivitis and pulpitis.

4. A method for preparing a mouthwash solution for treating oral inflammation according to any one of claims 1 to 3, characterized in that: include: Step S1, weighing the active ingredient according to the weight ratio, the total weight of the active ingredient is 250-350g; Step S2, adding 900-1000 ml of water to the effective ingredient, soaking it, boiling it with high heat, and then decocting it with low heat for 90-100 minutes, filtering it to obtain a first filter residue and 180-220 ml of a first filtrate; Step S3, adding 250-350 ml of water to the first filter residue, boiling over high heat, and then simmering over low heat for 30-40 minutes, filtering to obtain 80-120 ml of the second filtrate; Step S4: After the first filtrate is mixed with the second filtrate, the mouthwash liquid is obtained.

5. The method for preparing a mouthwash for treating oral inflammation according to claim 4, characterized in that: The step S1 also includes: after weighing the effective component, removing impurities from the effective component and drying it in the sun.

6. The method for preparing a mouthwash liquid for treating oral inflammation according to claim 4, characterized in that: In step S1, the total weight of the active ingredient is 300 g.

7. The method for preparing a mouthwash liquid for treating oral inflammation according to claim 4, characterized in that: In step S2, the active ingredient is soaked in water for 5 to 6 hours.

8. The method for preparing a mouthwash for treating oral inflammation according to claim 4, characterized in that: In step S3, 300 ml of water is added to the filter residue.

9. The method for preparing a mouthwash liquid for treating oral inflammation according to claim 4, characterized in that: In step S2, the first filtrate obtained is 200 ml; and in step S3, the second filtrate obtained is 100 ml.

10. The method for preparing a mouthwash liquid for treating oral inflammation according to claim 4, characterized in that: In step S4, the mouthwash liquid is also packaged and sealed, wherein each portion of the mouthwash liquid is 5 to 20 ml.