External control device, ventricular assist system, and control method for air bubble removal.

Abstract

This application discloses an external control device, a ventricular assist system, and a control method for bubble removal, relating to the field of ventricular assist technology. The external control device, applied to a ventricular assist system, includes a distance acquisition module and a bubble removal module. The distance acquisition module is used to acquire a safe distance and a current bubble movement distance in response to detecting a bubble in the perfusion tubing. The bubble removal module is used to compare the bubble movement distance and the safe distance, and based on the comparison result, control the removal of the bubble. The solution disclosed in this application solves the problem of poor bubble removal control in external control devices.

Description

Technical Field

[0001] This application relates to the field of ventricular assist technology, and in particular to an external control device, a ventricular assist system, and a method for controlling the expulsion of air bubbles. Background Technology

[0002] Typically, during the operation of a ventricular assist system, to prevent blood from entering the catheter pump and causing it to stop, the catheter pump is connected to the perfusion tubing, and the internal gaps of the catheter pump are flushed with perfusion fluid. However, air may enter the perfusion tubing during system operation. Therefore, it is necessary to detect the presence of air bubbles in the perfusion tubing and trigger an air bubble alarm.

[0003] Currently, the proposed solution involves installing a bubble sensor in the ventricular assist system to detect the presence of air bubbles in the perfusion tubing. Air bubbles typically pass through the bubble sensor very quickly, resulting in a short-lived and disappearing bubble alarm. However, bubbles may remain in the flow path after passing the sensor. If the alarm disappears, operators cannot ascertain the current bubble status, potentially leading to the risk of bubbles entering the body and posing a safety hazard. Summary of the Invention

[0004] This application provides an external control device, a ventricular assist system, and a method for controlling bubble expulsion, which solves the problem of poor bubble expulsion control in the external control device. The technical solution is as follows:

[0005] In a first aspect, an external control device is provided for use in a ventricular assist system, the external control device comprising:

[0006] The distance acquisition module is used to acquire the safe distance of the bubble and the current bubble movement distance in response to the detection of bubbles in the infusion line;

[0007] The bubble discharge module is used to compare and process the bubble movement distance and the bubble safety distance, and control the discharge of the bubble based on the comparison and processing results.

[0008] In one possible implementation, the distance acquisition module is further configured to, in response to detecting air bubbles in the infusion line, acquire the current infusion flow rate value, and determine the safe distance of the air bubble based on the current infusion flow rate value and using preset safety rules; wherein,

[0009] The preset safety rules include a preset constraint relationship between the infusion flow rate and the bubble safety distance, and a preset range of safety distance values ​​corresponding to the bubble safety distance. The preset constraint relationship between the infusion flow rate and the bubble safety distance is that the larger the infusion flow rate, the smaller the bubble safety distance.

[0010] In one possible implementation, the distance acquisition module is specifically used to determine the bubble safety distance based on the current infusion flow rate value and the preset safety distance range, by utilizing the preset constraint relationship between the infusion flow rate value and the bubble safety distance.

[0011] In one possible implementation, the distance acquisition module is further configured to obtain the bubble movement distance based on the radius of the infusion pipeline and the infusion flow rate, using a preset movement distance algorithm.

[0012] In one possible implementation, the distance acquisition module is specifically used to calculate the bubble movement distance corresponding to each preset time interval based on the radius of the infusion pipeline and the infusion flow rate value.

[0013] The bubble movement distance is accumulated and calculated for each preset time interval to obtain the current bubble movement distance.

[0014] In one possible implementation, the bubble discharge module is further configured to output a prompt message indicating a disconnection operation in response to the bubble movement distance being greater than or equal to the bubble safety distance, wherein the connector is disposed between the infusion line and the conduit pump;

[0015] Obtain the infusion pressure value;

[0016] In response to the infusion pressure being less than a preset pressure threshold, pressurization is applied to control the expulsion of the air bubbles.

[0017] In one possible implementation, the bubble removal module is further configured to increase the motor speed in response to the injection pressure value being less than a preset pressure threshold.

[0018] In response to the fulfillment of preset termination conditions, a prompt message indicating that the connector operation is completed is output.

[0019] In one possible implementation, the bubble discharge module is used to maintain the motor speed in response to the bubble movement distance being less than the bubble safety distance.

[0020] In one possible implementation, the external control device further includes an information display module;

[0021] The information display module is used to display prompts and processing progress indicators.

[0022] In one possible implementation, the external control device further includes a bubble detection module, a pressure detection module, and a motor speed adjustment module;

[0023] The bubble detection module is used to detect bubbles in the injection pipeline;

[0024] The pressure detection module is used to detect the injection pressure value;

[0025] The motor speed adjustment module is used to adjust the motor speed based on the detection result of the injection pressure value.

[0026] In a second aspect, a ventricular assist system is provided, the ventricular assist system comprising a catheter pump, a perfusion pump, a perfusion line, and an external control device as described in any of the above aspects and implementations;

[0027] The catheter pump is used to assist in pumping blood.

[0028] The infusion pump is used to pump the infusion fluid through the infusion pipeline to the conduit pump;

[0029] The infusion pipeline is connected to and disconnected from the conduit pump via a connector.

[0030] Thirdly, a method for controlling bubble discharge is provided, the method being applied to an external control device as described in any of the above aspects and implementations, the method comprising:

[0031] In response to the detection of air bubbles in the infusion line, the safe distance of the air bubble and the current distance of air bubble movement are obtained;

[0032] The bubble movement distance and the bubble safety distance are compared and processed, and the bubble discharge is controlled based on the comparison and processing results.

[0033] Fourthly, a computer-readable storage medium is provided, wherein at least one instruction is stored therein, the at least one instruction being loaded and executed by a processor to implement the aspects described above and any possible implementation thereof.

[0034] Fifthly, a programmable logic controller is provided, comprising:

[0035] At least one processor; and

[0036] A memory communicatively connected to the at least one processor; wherein,

[0037] The memory stores instructions that can be executed by the at least one processor to enable the at least one processor to perform the methods described above and any possible implementations.

[0038] The beneficial effects of the technical solution provided in this application include at least the following:

[0039] As can be seen from the above technical solution, in this embodiment of the application, the distance acquisition module of the external control device can detect bubbles in the infusion pipeline, acquire the bubble safety distance and the current bubble movement distance, and the bubble discharge module of the external control device can compare and process the bubble movement distance and the bubble safety distance. Based on the comparison and processing results, the bubble can be controlled to be discharged. Since the discharge of bubbles in the infusion pipeline can be controlled by comparing the size relationship between the bubble movement distance and the bubble movement distance, the bubbles in the infusion pipeline can be effectively discharged while ensuring the stability and reliability of the overall infusion operation.

[0040] It should be understood that the description in this section is not intended to identify key or essential features of the embodiments of this application, nor is it intended to limit the scope of this application. Other features of this application will become readily apparent from the following description. Attached Figure Description

[0041] To more clearly illustrate the technical solutions in the embodiments of this application, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0042] Figure 1 This is a schematic diagram of the architecture of an external control device provided in one embodiment of this application;

[0043] Figure 2 This is a schematic diagram of the structure of a ventricular assist system provided in another embodiment of this application;

[0044] Figure 3 This is a schematic diagram of the structure of a bubble sensor in an external control device provided in another embodiment of this application;

[0045] Figure 4 This is a side view of a bubble sensor in an external control device provided in another embodiment of this application;

[0046] Figure 5 This is a flowchart illustrating a bubble discharge control method provided in another embodiment of this application. Detailed Implementation

[0047] The following description, in conjunction with the accompanying drawings, illustrates exemplary embodiments of this application, including various details to aid understanding. These should be considered merely exemplary. Therefore, those skilled in the art will recognize that various changes and modifications can be made to the embodiments described herein without departing from the scope and spirit of this application. Similarly, for clarity and brevity, descriptions of well-known functions and structures are omitted in the following description.

[0048] Obviously, the described embodiments are only some, not all, of the embodiments in this application. All other embodiments obtained by those skilled in the art based on the embodiments in this application without inventive effort are within the scope of protection of this application.

[0049] It should be noted that the terminal devices involved in the embodiments of this application may include, but are not limited to, smart devices such as mobile phones, personal digital assistants (PDAs), wireless handheld devices, and tablet computers; the display devices may include, but are not limited to, personal computers, televisions, and other devices with display functions.

[0050] Furthermore, the term "and / or" in this article is merely a description of the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A existing alone, A and B existing simultaneously, or B existing alone. Additionally, the character " / " in this article generally indicates that the preceding and following related objects have an "or" relationship.

[0051] Typically, in ventricular assist systems, such as implantable left ventricular assist devices (LVADs), to prevent blood from entering the pump and causing it to stop during operation, the catheter pump is connected to the perfusion tubing, and the internal gaps of the catheter pump are flushed with perfusion fluid. However, air may enter the perfusion tubing. Traditional pressure sensors cannot detect small air bubbles quickly enough. Therefore, bubble sensors, such as ultrasonic sensors or capacitive sensors, can be used to detect small air bubbles in the perfusion tubing. Air bubbles usually pass through the bubble sensor in a very short time, so the corresponding bubble alarm is short-lived and disappears quickly. However, air bubbles may remain in the flow channel after passing through the bubble sensor. If the bubble alarm disappears, the operator will not know the current status of the air bubbles, potentially leading to the risk of air bubbles entering the body and posing a safety hazard. Moreover, the solutions in related technologies immediately stop perfusion after detecting air bubbles, which cannot guarantee the stable operation of the perfusion system.

[0052] Therefore, there is an urgent need for an external control device that can accurately remove air bubbles from the infusion pipeline while ensuring the stability of the overall infusion operation.

[0053] Please refer to Figure 1 This illustrates a schematic diagram of the architecture of an external control device provided in one embodiment of this application. Figure 1As shown, in this embodiment, the external control device 100 can be applied to a ventricular assist system. The external control device may include a flow acquisition module 101 and a bubble removal module 102.

[0054] The distance acquisition module 101 can be used to acquire the safe distance of the bubble and the current bubble movement distance in response to the detection of bubbles in the infusion pipeline.

[0055] The bubble discharge module 102 can be used to compare the bubble movement distance and the bubble safety distance, so as to control the discharge of the bubble based on the comparison result.

[0056] It should be noted that the bubble safety distance can be a projected safe distance from which bubble removal is not required; that is, the distance between the detected bubble position and the safe position where bubble removal is not necessary. The bubble travel distance can be the distance between the detected bubble position and the real-time position of the bubble.

[0057] It should be noted that the comparison results can include bubble movement distances greater than or equal to the bubble safety distance, and bubble movement distances less than the bubble safety distance.

[0058] In this way, the discharge of air bubbles in the infusion pipeline can be controlled by comparing the magnitude of the air bubble movement distance with that of the air bubble movement distance through an external control device. This can effectively discharge air bubbles from the infusion pipeline while ensuring the stability and reliability of the overall infusion operation.

[0059] Optionally, in one possible implementation of this embodiment, the distance acquisition module 101 can also be used to acquire the current infusion flow rate value in response to detecting air bubbles in the infusion pipeline, so as to determine the safe distance of the air bubble based on the current infusion flow rate value and using preset safety rules.

[0060] In this implementation, the preset safety rules include a preset constraint relationship between the infusion flow rate and the bubble safety distance, and a preset range of safety distance values ​​corresponding to the bubble safety distance. The preset constraint relationship between the infusion flow rate and the bubble safety distance is that the larger the infusion flow rate, the smaller the bubble safety distance.

[0061] It is understandable that, in practical applications, the preset security rules can be determined based on the actual application scenario.

[0062] In one specific implementation of this method, the distance acquisition module 101 can be used to determine the bubble safety distance based on the current infusion flow rate value and the preset safety distance range by utilizing the preset constraint relationship between the infusion flow rate value and the bubble safety distance.

[0063] In one specific implementation, the distance acquisition module 101 can be used to calculate the bubble safety distance based on the current infusion flow rate value by utilizing a preset constraint relationship between the infusion flow rate value and the bubble safety distance, wherein the bubble safety distance is within a preset safety distance value range.

[0064] Preferably, the preset constraint relationship between the injection flow rate and the bubble safety distance can be expressed as formula (1):

[0065] d=f1(Q) (1)

[0066] Where d is the bubble safety distance, Q is the infusion flow rate when a bubble is detected, and the value of d is in the range of (0, D), which is the preset safety distance range. D can be a preset value, for example, D can be the distance between the detected bubble position and the position of the conduit pump connector.

[0067] Here, the bubble safety distance can be the distance between the detected bubble position and the position that satisfies the preset constraint relationship. The bubble safety distance should be within the preset safety distance range.

[0068] In this way, when air bubbles are detected in the infusion line, a safe distance for air bubbles that conforms to the preset safety rules can be obtained based on the current infusion flow rate value and the preset safety rules, thereby improving the accuracy of the safe distance for air bubbles and thus improving the reliability of subsequent air bubble discharge control.

[0069] In another specific implementation of this method, the distance acquisition module 101 can further be used to obtain the bubble movement distance based on the radius of the infusion pipeline and the infusion flow rate value using a preset movement distance algorithm.

[0070] In one specific implementation, the distance acquisition module 101 can also be used to calculate the bubble movement distance corresponding to each preset time interval based on the radius of the infusion pipeline and the infusion flow rate value, and then accumulate the bubble movement distance of each preset time interval to obtain the current bubble movement distance.

[0071] In this specific implementation process, the radius of the injection pipeline can be the radius of the inner wall of the pipeline, that is, the inner diameter of the injection pipeline. The injection flow rate value can be the real-time value of the injection flow rate.

[0072] Preferably, the distance acquisition module 101 can be used to acquire the infusion flow rate value, and calculate the current bubble movement distance d1 according to the following formula (2) based on the radius of the infusion pipeline and the infusion flow rate value at a preset time interval:

[0073]

[0074] Where r is the radius of the injection pipeline, Q is the injection flow rate, and Δt is the preset time interval. Preferably, Δt can be 1 second (s).

[0075] In this way, the distance the bubble travels can be calculated in real time, enabling real-time detection of the bubble's position. This allows for accurate control of bubble discharge based on the comparison between the bubble's travel distance and its safe distance.

[0076] In another specific implementation of this method, the distance acquisition module 101 may include a flow meter. The distance acquisition module 101 may also be used to directly acquire the current infusion flow rate value through the flow meter in response to the detection of air bubbles in the infusion pipeline.

[0077] In another specific implementation of this method, the distance acquisition module 101 can also be used to acquire the current motor speed detected by the external control device in response to the detection of air bubbles in the infusion pipeline, and obtain the current infusion flow rate value based on the current motor speed and using the preset correlation between the motor speed and the infusion flow rate value.

[0078] In another specific implementation of this method, the distance acquisition module 101 can also be used to obtain the current infusion pressure value detected by the external control device in response to the detection of air bubbles in the infusion pipeline, and obtain the current infusion flow rate value based on the current infusion pressure value and using the preset correlation between the infusion pressure value and the infusion flow rate value.

[0079] In this specific implementation, the infusion flow rate and infusion pressure are inversely proportional. An external control device can be used to detect the infusion pressure.

[0080] In another specific implementation of this method, the distance acquisition module 101 can also be used to acquire the current motor speed and infusion pressure value detected by the external control device in response to the detection of air bubbles in the infusion pipeline, and estimate the current infusion flow rate value based on the current motor speed and infusion pressure value using a preset fluid dynamics model.

[0081] It is understandable that other existing methods can also be used to obtain the injection flow rate value corresponding to the moment when air bubbles are detected in the injection pipeline, and no specific limitation is made here.

[0082] Optionally, in one possible implementation of this embodiment, the bubble discharge module 102 can also be used to output a prompt message indicating that the connector is disconnected in response to the bubble movement distance being greater than or equal to the bubble safety distance. The connector is located between the infusion pipeline and the conduit pump. In response to the operator disconnecting the connector, the infusion pressure value is obtained. In response to the infusion pressure value being less than a preset pressure threshold, pressurization is performed to control the discharge of the bubble.

[0083] In this implementation, the preset pressure threshold can be determined based on the configuration of the actual external control device. For example, the preset pressure threshold can be 50 mmHg.

[0084] In one specific implementation of this method, the bubble discharge module 102 can be used to increase the motor speed in response to the injection pressure value being less than a preset pressure threshold, and to output a prompt message indicating that the connector operation is connected in response to the motor speed meeting a preset termination condition.

[0085] In this implementation, the motor speed may include the speed of the infusion pump motor of the external control device.

[0086] In one specific implementation, the bubble discharge module 102 can be used to increase the motor speed of the infusion pump when the infusion pressure value is less than a preset pressure threshold, so as to adjust the motor speed to a preset motor speed until the preset termination condition is met, and output a prompt message to connect the connector.

[0087] In this implementation, the preset termination condition may include the motor running a preset number of revolutions at a preset motor speed.

[0088] For example, the preset motor speed can be n1, and the value of n1 can be in the range of 0.1 revolutions per second (r / s) < n1 < 1 r / s. The preset number of revolutions can be N, for example, N can be 2 revolutions. Here, the motor speed of the injection pump motor can be adjusted to n1. After the injection pump motor completes N revolutions at speed n1, a prompt message for connecting the connector is output to remind the operator to perform the connection operation.

[0089] In this way, when the bubble travels a distance greater than or equal to the bubble safety distance, a prompt message for disconnecting the connector can be output. Based on the instruction determined by the operator's disconnection operation, the injection pressure value can be obtained. When the injection pressure value is less than the preset pressure threshold, pressurization is performed to control the expulsion of the bubble, which can further improve the reliability of bubble expulsion control.

[0090] Optionally, in one possible implementation of this embodiment, the bubble discharge module 102 may be used to output a prompt message for disconnecting the connector in response to the bubble movement distance being greater than or equal to the bubble safety distance, to obtain the injection pressure value in response to the operator not performing the disconnection operation, and to stop the motor and output an alarm message in response to the injection pressure value being greater than a preset pressure threshold and the bubble movement distance reaching a preset distance threshold.

[0091] In this implementation, the preset distance threshold can be determined based on the distance between the detected bubble location and the location of the conduit pump connector. For example, where D is the distance between the detected bubble location and the location of the conduit pump connector, the preset distance threshold can be 0.9D.

[0092] Optionally, in one possible implementation of this embodiment, the bubble discharge module 102 can also be used to maintain the motor speed in response to the bubble movement distance being less than the bubble safety distance.

[0093] In this way, the current injection flow rate can be kept constant when the bubble travels a distance less than the safe bubble distance, thus maximizing the stability of the injection.

[0094] Optionally, in one possible implementation of this embodiment, the external control device 100 may further include an information display module. The information display module can be used to display prompts and processing progress indicators.

[0095] In this implementation, the information display module may include an operable display screen of an external control device.

[0096] Optionally, in one possible implementation of this embodiment, the external control device may further include a bubble detection module, a pressure detection module, and a motor speed adjustment module. The bubble detection module is used to detect bubbles in the infusion tubing. The pressure detection module is used to detect the infusion pressure value. The motor speed adjustment module is used to adjust the motor speed based on the detected infusion pressure value.

[0097] In this implementation, the bubble detection module may include a bubble sensor. The pressure detection module may include a pressure sensor.

[0098] Figure 2 This is a schematic diagram of a ventricular assist system provided in another embodiment of this application. To better understand the system in this embodiment, the following is a description in conjunction with the accompanying drawings. Figure 2 To be continued Figure 4 The system of the embodiments of this application will be described in terms of specific application scenarios.

[0099] like Figure 2 As shown in the embodiments of this application, the ventricular assist system 200 may include an external control device 1, a catheter pump 2, a perfusion pump 13, and a perfusion line 14.

[0100] The catheter pump 2 can be used to assist in pumping blood. The catheter pump 2 is connected to the perfusion line 14 via connector 21.

[0101] The infusion pump 13 can be used to pump the infusion fluid through the infusion pipeline 14 to the conduit pump 2.

[0102] The infusion line 14 is connected to and disconnected from the conduit pump 2 via a connector 21.

[0103] The external control device 1 may include a distance acquisition module and a bubble removal module. The distance acquisition module is used to acquire a safe distance between the bubble and the current bubble movement distance in response to detecting a bubble in the infusion tubing. The bubble removal module is used to compare the bubble movement distance and the safe distance between the bubble, and based on the result of the comparison, to control the removal of the bubble.

[0104] Alternatively, in one possible implementation of this embodiment, connector 21 can be a Luer connector.

[0105] Optionally, in one possible implementation of this embodiment, such as Figure 2 As shown, the external control device 1 may also include a bubble sensor 11 and a pressure sensor 12.

[0106] Figure 3 This is a schematic diagram of the structure of a bubble sensor in an external control device provided in another embodiment of this application. Figure 4 This is a side view of a bubble sensor in an external control device provided in another embodiment of this application.

[0107] Preferably, such as Figure 3 and Figure 4 As shown, the bubble sensor may include an upper housing 110 and a lower housing 111. The distance H between the upper housing 110 and the lower housing 111 should be slightly smaller than the outer diameter of the filling pipeline 14, preferably, H can be 2 millimeters (mm). This ensures the detection accuracy of the bubble sensor and prevents the pipeline from becoming loose.

[0108] Preferably, such as Figure 4 As shown, the injection line 14 contains injection fluid 31 and air bubbles 4.

[0109] Preferably, such as Figure 2 As shown, the bubble sensor 11 can be installed behind the pressure sensor 12 to facilitate the detection of bubble discharge time.

[0110] Preferably, such as Figures 2 to 4 As shown, in the ventricular assist system 200, the catheter pump 2 is connected to the perfusion line 14 to prevent blood from entering the catheter pump 2. The external control device 1 can also pump the perfusion fluid 31 in the infusion bag 3 to the distal end of the catheter pump 2 via the perfusion pump 13 to flush the internal gaps of the catheter pump 2. During the operation of the ventricular assist system 200, air may enter the perfusion line 14 due to leakage. The external control device 1 can integrate a bubble sensor 11. When there is only perfusion fluid in the perfusion line 14, the flow of the fluid is not affected, and the signal received by the bubble sensor 11 remains unchanged. When the perfusion fluid 31 in the infusion bag 3 is low or the perfusion line 14 is disconnected, causing air to enter the line, the signal received by the sensor changes due to the difference in acoustic impedance or dielectric parameters between the gas and the liquid, thus detecting the presence of bubbles 4.

[0111] Optionally, in one possible implementation of this embodiment, the distance acquisition module of the external control device 1 can also be used to determine the bubble safety distance based on the current infusion flow rate and the preset safety distance range by utilizing the preset constraint relationship between the infusion flow rate value and the bubble safety distance.

[0112] In this embodiment, the preset constraint relationship between the infusion flow rate and the bubble safety distance can be that the larger the infusion flow rate, the smaller the bubble safety distance.

[0113] Here, the infusion pressure and infusion flow rate are inversely proportional. The infusion pressure P can be measured by the pressure sensor 12 of the external control device 1. To ensure that air bubbles can be discharged in a timely manner, the larger the infusion flow rate, the smaller the safe distance for air bubbles. The safe distance d can be in the range of (0, D), and the preset safe distance range can be (0, D), where D is the distance from the air bubble sensor 11 to the Luer connector 21 of the tubing pump 2.

[0114] Understandably, setting a bubble safety distance can extend the priming time to some extent. When the bubble sensor detects a bubble, the bubble will not immediately enter the pipeline after Luer connector 21. By not immediately stopping priming upon detecting a bubble, the priming time can be extended. Correspondingly, a certain time t0 is required from issuing the bubble purging warning message to the operator disconnecting Luer connector 21. Therefore, when determining the specific value of the bubble safety distance, a margin of time must be allowed for the purging operation, ensuring that D minus d is greater than or equal to the distance the bubble travels within t0, to prevent bubbles from entering the pipeline after Luer connector 21 before Luer connector 221 is disconnected.

[0115] For example, D can be 2 meters (m) to 3 meters. If the infusion flow rate is 30 milliliters per hour (ml / h), d can be any value between 1.2 meters and 1.8 meters.

[0116] Optionally, in one possible implementation of this embodiment, the bubble discharge module of the external control device 1 can also be used to output a prompt message for disconnecting the connector in response to the bubble movement distance being greater than or equal to the bubble safety distance. The connector is located between the infusion pipeline and the catheter pump. In response to the operator disconnecting the connector, the infusion pressure value is obtained. In response to the infusion pressure value being less than a preset pressure threshold, pressurization is performed to control the discharge of the bubble.

[0117] Alternatively, it can be used to maintain the motor speed in response to the bubble movement distance being less than the bubble safety distance.

[0118] Alternatively, it can be used to output a prompt message indicating that the connector should be disconnected in response to the bubble movement distance being greater than or equal to the bubble safety distance; to obtain the injection pressure value in response to the operator not performing the disconnection operation; and to stop the motor and output an alarm message in response to the injection pressure value being greater than a preset pressure threshold and the bubble movement distance reaching a preset distance threshold.

[0119] For example, the bubble movement distance can be d1, and the bubble safety distance can be d. When d1 < d, the current infusion flow rate can be kept constant, that is, the current speed of the infusion pump motor can be kept constant. When d1 ≥ d, the external control device 1 can output a prompt to disconnect the Luer connector 21 to control the bubble discharge. When the Luer connector 21 of the catheter pump 2 is disconnected, the infusion pressure P drops rapidly. The real-time infusion pressure can be detected by the pressure sensor 12. When the infusion pressure P ≤ 50 mmHg, the external control device 1 sends a pressurization control message to the infusion pump motor to increase the motor speed n1, for example, 0.1 r / s < n1 < 1 r / s, to increase the infusion flow rate and control the rapid discharge of bubbles. After the infusion pump motor has rotated N revolutions at a speed of n1, the external control device 1 controls the air bubbles to be expelled and outputs a prompt message to the operator to quickly connect the Luer connector. It also adjusts the speed of the infusion pump motor to ensure that the infusion motor performs infusion at a normal infusion flow rate, such as 30 ml / h.

[0120] Understandably, the preset number of revolutions N is primarily designed to ensure complete venting within this operating time. Preferably, N can be 2 revolutions. Since the external control device 1 issues a pressurization command during venting, the pressure within the infusion line can be maintained at a certain level. For example, the infusion pressure within the infusion line can be greater than 300 mmHg, and after connecting the Luer connector 21, it can quickly return to a normal flushing flow rate of 30 ml / h inside the catheter pump 2.

[0121] For example, if the operator does not disconnect the Luer connector 21 and the external control device 1 detects an infusion pressure value P > 50 mmHg and d1 = 0.9D, the external control device 1 can stop the operation of the infusion pump motor and display an advanced alarm indicating that air has entered the infusion line.

[0122] Thus, the ventricular assist system in this embodiment can integrate a bubble sensor into the external control device. When air enters the perfusion tubing, the external control device judges and processes the obtained baseline bubble safety distance and bubble movement distance to ensure timely bubble discharge. When the bubble movement distance is less than the bubble safety distance, the current perfusion flow rate remains unchanged. As the bubble continues to move forward, when the bubble movement distance reaches the bubble safety distance, the external control device can prompt the operator to disconnect the Luer connector and increase the perfusion flow rate to quickly discharge the bubble from the perfusion tubing, thereby ensuring the accuracy of air venting.

[0123] Furthermore, by employing the ventricular assist system in this embodiment, when the bubble movement distance is less than the bubble safety distance, the current perfusion flow rate remains unchanged, which can maximize the stability of perfusion.

[0124] Figure 5 This is a flowchart illustrating a bubble discharge control method provided in another embodiment of this application, as shown below. Figure 5 As shown. In this embodiment, the bubble discharge control method can be applied to the external control device described in the foregoing embodiments, and the bubble discharge control method may include:

[0125] Step 501: In response to the detection of air bubbles in the infusion line, obtain the safe distance of the air bubble and the current distance of air bubble movement.

[0126] Step 502: Compare the bubble movement distance and the bubble safety distance to control the discharge of the bubble based on the comparison results.

[0127] In this way, by responding to the detection of air bubbles in the infusion pipeline, the safe distance of the air bubble and the current air bubble movement distance can be obtained. Then, the air bubble movement distance and the safe distance of the air bubble can be compared and processed. Based on the comparison and processing results, the air bubble can be controlled to be discharged. Since the discharge of air bubbles in the infusion pipeline can be controlled by comparing the size relationship between the air bubble movement distance and the air bubble movement distance, the air bubbles in the infusion pipeline can be effectively discharged while ensuring the stability and reliability of the overall infusion operation.

[0128] Optionally, in one possible implementation of this embodiment, in step 501, firstly, in response to detecting air bubbles in the infusion line, the current infusion flow rate value can be obtained. Secondly, based on the current infusion flow rate value, a preset safety rule can be used to determine the safe distance of the air bubble.

[0129] In this implementation, the preset safety rules include a preset constraint relationship between the infusion flow rate and the bubble safety distance, and a preset range of safety distance values ​​corresponding to the bubble safety distance. The preset constraint relationship between the infusion flow rate and the bubble safety distance is that the larger the infusion flow rate, the smaller the bubble safety distance.

[0130] In one specific implementation of this method, the bubble safety distance is determined based on the current infusion flow rate and the preset range of the safety distance, utilizing the pre-defined constraint relationship between the infusion flow rate and the bubble safety distance.

[0131] In one specific implementation, the bubble safety distance can be calculated based on the current infusion flow rate by utilizing a preset constraint relationship between the infusion flow rate and the bubble safety distance, and the bubble safety distance is within the preset safety distance range.

[0132] It is understandable that, here, the bubble safety distance can be the distance between the detected bubble position and the position that satisfies the preset constraint relationship. The bubble safety distance should be within the preset safety distance range. The detected bubble position can be the position of the bubble sensor.

[0133] In another specific implementation of this method, the bubble movement distance is obtained based on the radius of the injection pipeline and the injection flow rate, using a preset movement distance algorithm.

[0134] One specific implementation process involves first calculating the bubble movement distance for each preset time interval based on the radius of the infusion pipeline and the infusion flow rate. Second, the bubble movement distances for each preset time interval are accumulated to obtain the final bubble movement distance.

[0135] Optionally, in one possible implementation of this embodiment, in step 502, a prompt message for disconnecting the connector can be output in response to the bubble movement distance being greater than or equal to the bubble safety distance. The connector is located between the infusion pipeline and the conduit pump, thereby obtaining the infusion pressure value. In response to the infusion pressure value being less than a preset pressure threshold, pressurization is performed to control the discharge of the bubble.

[0136] In one specific implementation of this method, the motor speed can be increased in response to the injection pressure value being less than a preset pressure threshold. A prompt message indicating that the connector operation is completed is output in response to the preset termination condition being met.

[0137] In one specific implementation process, when the injection pressure is less than a preset pressure threshold, the motor speed of the injection pump is increased to adjust the motor speed to a preset speed until the preset termination condition is met, and a prompt message for connecting the connector is output.

[0138] In this implementation, the preset termination condition may include the motor running a preset number of revolutions at a preset motor speed.

[0139] It should be noted that the specific implementation process provided in this embodiment can be combined with various specific implementation processes provided in the foregoing implementation methods to realize the bubble discharge control method of this embodiment. Detailed descriptions can be found in the relevant content of the foregoing implementation methods, and will not be repeated here.

[0140] Optionally, in one possible implementation of this embodiment, in step 502, the motor speed can be maintained in response to the bubble movement distance being less than the bubble safety distance.

[0141] Optionally, in one possible implementation of this embodiment, in step 502, a prompt message for disconnecting the connector may be output in response to the bubble movement distance being greater than or equal to the bubble safety distance; in response to the operator not performing the disconnection operation, the injection pressure value may be obtained; in response to the injection pressure value being greater than a preset pressure threshold and the bubble movement distance reaching a preset distance threshold, the motor may be stopped and an alarm message may be output.

[0142] It should be noted that the specific implementation process provided in this embodiment can be combined with various specific implementation processes provided in the foregoing implementation methods to realize the bubble discharge control method of this embodiment. Detailed descriptions can be found in the relevant content of the foregoing implementation methods, and will not be repeated here.

[0143] It should be noted that, for the sake of simplicity, the foregoing embodiments are all described as a series of actions. However, those skilled in the art should understand that this application is not limited to the described order of actions, as some steps may be performed in other orders or simultaneously according to this application. Furthermore, those skilled in the art should also understand that the embodiments described in the specification are preferred embodiments, and the actions and modules involved are not necessarily essential to this application.

[0144] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions in other embodiments.

[0145] The technical solution of this application involves the collection, storage, use, processing, transmission, provision, and disclosure of user personal information, such as user image and attribute data, which comply with relevant laws and regulations and do not violate public order and good morals.

[0146] Those skilled in the art will understand that all or part of the steps of the above embodiments can be implemented by hardware or by a program instructing related hardware. The program can be stored in a computer-readable storage medium, such as a read-only memory, a disk, or an optical disk.

[0147] It should be understood that the various forms of processes shown above can be used to rearrange, add, or delete steps. For example, the steps described in this disclosure can be executed in parallel, sequentially, or in different orders, as long as the desired result of the technical solution disclosed in this application can be achieved, and this is not limited herein.

[0148] The specific embodiments described above do not constitute a limitation on the scope of protection of this application. Those skilled in the art should understand that various modifications, combinations, sub-combinations, and substitutions can be made according to design requirements and other factors. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this application should be included within the scope of protection of this application.

Claims

1. An external control device, characterized in that, The external control device, used in ventricular assist systems, includes: The distance acquisition module is used to acquire the safe distance of the bubble and the current bubble movement distance in response to the detection of bubbles in the infusion line; A bubble ejection module is used to compare and process the bubble movement distance and the bubble safety distance, so as to control the ejection of the bubble based on the comparison and processing results; The distance acquisition module is further configured to, in response to detecting air bubbles in the infusion pipeline, acquire the current infusion flow rate value, and determine the safe distance of the air bubble based on the current infusion flow rate value and using preset safety rules; wherein, The preset safety rules include a preset constraint relationship between the infusion flow rate and the bubble safety distance, and a preset range of safety distance values ​​corresponding to the bubble safety distance. The preset constraint relationship between the infusion flow rate and the bubble safety distance is that the larger the infusion flow rate, the smaller the bubble safety distance. The distance acquisition module is also used to obtain the bubble movement distance based on the radius of the infusion pipeline and the infusion flow rate, using a preset movement distance algorithm.

2. The apparatus according to claim 1, characterized in that, The distance acquisition module is specifically used to determine the bubble safety distance based on the current infusion flow rate and the preset safety distance range by utilizing the preset constraint relationship between the infusion flow rate value and the bubble safety distance.

3. The apparatus according to claim 1, characterized in that, The distance acquisition module is specifically used to calculate the bubble movement distance corresponding to each preset time interval based on the radius of the infusion pipeline and the infusion flow rate value according to a preset time interval. The bubble movement distance is accumulated and calculated for each preset time interval to obtain the current bubble movement distance.

4. The apparatus according to claim 1, characterized in that, The bubble discharge module is also used to output a prompt message for disconnecting the connector in response to the bubble movement distance being greater than or equal to the bubble safety distance. The connector is located between the infusion pipeline and the conduit pump. Obtain the infusion pressure value; In response to the infusion pressure being less than a preset pressure threshold, pressurization is applied to control the expulsion of the air bubbles.

5. The apparatus according to claim 4, characterized in that, The bubble discharge module is also used to increase the motor speed in response to the injection pressure value being less than a preset pressure threshold. In response to the fulfillment of preset termination conditions, a prompt message indicating that the connector operation is completed is output.

6. The apparatus according to claim 1, characterized in that, The bubble discharge module is used to maintain the motor speed in response to the bubble movement distance being less than the bubble safety distance.

7. The apparatus according to claim 1, characterized in that, The external control device also includes an information display module; The information display module is used to display prompts and processing progress indicators.

8. The apparatus according to claim 1, characterized in that, The external control device also includes a bubble detection module, a pressure detection module, and a motor speed adjustment module; The bubble detection module is used to detect bubbles in the injection pipeline; The pressure detection module is used to detect the injection pressure value; The motor speed adjustment module is used to adjust the motor speed based on the detection result of the injection pressure value.

9. A ventricular assist system, characterized in that, The ventricular assist system includes a catheter pump, a perfusion pump, a perfusion line, and an external control device according to any one of claims 1-8; The catheter pump is used to assist in pumping blood. The infusion pump is used to pump the infusion fluid through the infusion pipeline to the conduit pump; The infusion pipeline is connected to and disconnected from the conduit pump via a connector.

10. A method for controlling bubble discharge, characterized in that, The method is applied to an external control device as described in any one of claims 1-8, the method comprising: In response to the detection of air bubbles in the infusion line, the safe distance of the air bubble and the current distance of air bubble movement are obtained; The bubble movement distance and the bubble safety distance are compared and processed, and the bubble discharge is controlled based on the comparison and processing results.

11. A non-transitory computer-readable storage medium storing computer instructions, characterized in that, The computer instructions are used to cause the computer to perform the method according to claim 10.

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