Acaricide and application thereof

Abstract

The invention belongs to the technical field of pesticide mite killing, and discloses an acaricide and application thereof.The acaricide comprises an active component A and an active component B. The active component A is a compound shown in the formula I: # imgabs0, the active component B is any one of etoxazole, lufenuron or flufenoxystrobin, and the mass ratio of the active component A to the active component B is 1: 50-45: 1. The acaricide disclosed by the invention has an excellent prevention and treatment effect on common harmful mites on crops and garden plants, and can effectively reduce the use amount of pesticides and reduce the harm to the environment.

Description

[0001] This invention application is a divisional application with application number 202311368221.X, application date October 23, 2023, and invention name “A miticide and its application”. Technical Field

[0002] The invention belongs to the technical field of pesticide acaricide and discloses an acaricide and application thereof. Background Art

[0003] Ethoxazole, CAS No.: 153233-91-1, chemical name: 4-(4-tert-butyl-2-ethoxyphenyl)-2-(2,6-difluorophenyl)-4,5-dihydro-1,3-oxazole, is an oxazole acaricide, a diphenyloxazoline derivative, which mainly inhibits the normal molting process of mites and has ovicidal activity, so it can effectively control the entire juvenile stage of mites and also cause female adult mites to be infertile. Its main control targets are red spider mites in apples and citrus, and it also has excellent control effects on mites such as spider mites, early spider mites, panonychus mites, two-spotted spider mites, and cinnabar spider mites in crops such as cotton, flowers, and vegetables.

[0004] Lufenuron, CAS number: 103055-07-8, chemical name: N-[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl]-2,6-difluorobenzamide, is a chitin synthesis inhibitor. Its mechanism of action is to inhibit the enzyme that catalyzes chitin polymerization in harmful mites / insects, thereby interfering with the normal growth and development of insects.

[0005] Fluopyrim, CAS No.: 918162-02-4, chemical name: (2E)-2-(2-{[2-chloro-4-(trifluoromethyl)phenoxy]methyl}phenyl)-3-methoxyacrylate, is a methoxyacrylate-based highly effective fungicide and miticide. It can be used to control diseases caused by ascomycetes, basidiomycetes and conjugated fungi, such as wheat rust, powdery mildew, cucumber powdery mildew, anthracnose, black spot, corn leaf blight, rice sheath blight, etc. It also has high activity against mites such as spider mites on apples and citrus, such as red spider mites.

[0006] Mites are a type of herbivorous arthropods belonging to the phylum Arthropoda, class Arachnida, order Acari. They have a small number of individuals, a wide range of activities, rapid reproduction in high temperature and drought, a short generation cycle, and strong drug resistance. Agricultural pest mites are one of the most difficult biological groups to control in the world. There are more than 40 species of agricultural pest mites in my country, which have a strong destructive ability to economic crops such as fruit trees, vegetables, and flowers, seriously affecting the normal physiological functions of crop leaves and even reducing production. At present, the prevention and control of pest mites mainly adopts chemical prevention and control methods, and acaricides are the main means of modern agricultural prevention and control of pest mites. In agricultural production, the effectiveness of pest mites against various acaricides has decreased year by year. After research, the applicant found that compounding sulfiflumin with etoxazole, lufenuron or fluazifop-butyl in a suitable mass ratio has a significant synergistic effect on pest mites, effectively improving the control effect of field pest mites, and is safe for plants, reducing the amount of pesticides used, and reducing environmental pollution. Summary of the invention

[0007] Based on the above, the object of the present invention is to provide a miticide, which has a significant synergistic effect on harmful mites on agricultural and garden plants, can effectively reduce the amount of pesticides used, and reduce harm to the environment.

[0008] In order to achieve the above object, the present invention adopts the following technical scheme: an acaricide, the acaricide comprises an active ingredient A and an active ingredient B, the active ingredient A is a compound of formula I: The active ingredient B is any one of etoxazole, lufenuron or fluazifop-butyl;

[0009] Furthermore, the mass ratio of active ingredient A to active ingredient B in the acaricide is 1:50 to 45:1.

[0010] Furthermore, the mass ratio of active ingredient A to active ingredient B in the acaricide is 1:45 to 35:1;

[0011] Furthermore, the active ingredient B is etoxazole, and the mass ratio of the active ingredient A to the active ingredient B is 1:45 to 35:1;

[0012] The active ingredient B is lufenuron, and the mass ratio of the active ingredient A to the active ingredient B is 1:35 to 35:1;

[0013] The active ingredient B is flutosan, and the mass ratio of the active ingredient A to the active ingredient B is 1:30 to 15:1;

[0014] Furthermore, based on the total weight of the acaricide being 100%, the total weight of the active ingredient A and the active ingredient B accounts for 0.1% to 80% of the total weight of the fungicide composition;

[0015] Furthermore, the acaricide contains auxiliary ingredients permitted in pesticides in addition to the active ingredients, and the auxiliary ingredients are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoaming agents, solvents, preservatives, stabilizers, synergists, binders, fillers or carriers.

[0016] Furthermore, the acaricide can be prepared into a pesticide acceptable formulation, which is a solid formulation or a liquid formulation.

[0017] Further, the solid preparation is a granule, a strip, a wettable powder, an oil-dispersible powder, an emulsion, a water-dispersible granule, an emulsion, a water-dispersible tablet, a soluble powder, a soluble tablet or a soluble granule, and the liquid preparation is a soluble solution, a soluble gel, an oil, a film-spreading oil, an emulsifiable concentrate, a latex, a dispersible liquid, an ointment, an aqueous emulsion, an oil emulsion, a microemulsion, a fat, a suspension, a microcapsule suspension, an oil suspension, a dispersible oil suspension or a suspoemulsion;

[0018] Furthermore, the solid preparation is a wettable powder or a water-dispersible granule, and the liquid preparation is an emulsifiable concentrate, an aqueous suspension, or a water-dispersible granule;

[0019] The invention also discloses the use of the above-mentioned acaricide for preventing and controlling harmful mites of crops and garden plants.

[0020] Furthermore, the plant pest mites are Tetranychus cinnabarinus, Tetranychus urticae, and Panonychus citri.

[0021] The present invention has the following advantages:

[0022] The acaricide of the present invention has a significant synergistic effect on common harmful mites on agricultural and garden plants, and has a good control effect on cinnabarinus spider mites, two-spotted spider mites and citrus red spiders. It can slow down the development of drug resistance of harmful mites, reduce the amount of pesticides used, and is safe for plants and friendly to the environment. DETAILED DESCRIPTION

[0023] In order to make the technical solution of the present invention more clear, the present invention is explained and illustrated in conjunction with specific preparation examples and embodiments.

[0024] Preparation Example:

[0025] Preparation Example 1: 27% sulfiflumin·ethoxazole suspension (1:8)

[0026] Formula composition: 3% sulfiflumin, 24% etoxazole, 1% fatty alcohol polyoxyethylene ether, 5% styrene phenol polyoxyethylene ether phosphate, 1% sodium lignin sulfonate, 0.25% xanthan gum, 5% ethylene glycol, 0.1% sodium benzoate, 0.5% silicone oil, and deionized water to make up the balance;

[0027] Preparation method: According to the formula ratio, the active ingredients, surfactants and other functional additives are placed in a reactor in sequence, water is added to mix evenly, and the suspension product is obtained by high-speed shearing, wet sand grinding, and finally homogenization filtration.

[0028] Preparation Example 2: 42% sulfiflumin·ethoxazole water dispersible granules (5:1)

[0029] Formula composition: 35% sulfiflumin, 7% etoxazole, 8% sodium lignin sulfonate, 2% BX powder, 8% sodium polycarboxylate, 4% ammonium sulfate, and kaolin makes up the balance;

[0030] Preparation method: according to the formula ratio of the embodiment, the active ingredient is added to the carrier, and the surfactant and other functional additives are added thereto, mixed, and after air flow pulverization, 10-25% of water is added, and then kneading, granulation, drying, and sieving are performed to obtain a water-dispersible granule product; or the pulverized powder is sprayed with water in a boiling granulator, granulated, dried, and then sieved to obtain the product.

[0031] Preparation Example 3: 16% sulfiflumin·ethoxazole emulsifiable concentrate (1:3)

[0032] Formula composition: 4% sulfiflumin, 12% etoxazole, 15% EO / PO block copolymer, 12% acetophenone, 10% propylene glycol methyl ether, 1% calcium dodecylbenzene sulfonate, and xylene makes up the balance;

[0033] Preparation method: according to the formula ratio of the embodiment, the measured active ingredients, solvents and co-solvents are added into a mixing kettle and stirred to dissolve, then an emulsifier is added, and the balance is supplemented with the remaining solvent, and the mixture is stirred evenly in a stirring kettle, and the desired emulsifiable concentrate of the present invention is obtained after filtering.

[0034] Preparation Example 4: 12% sulfiflumin·lufenuron emulsifiable concentrate (1:2)

[0035] Formula composition: 4% sulfiflumin, 8% lufenuron, 15% N-methylpyrrolidone, 14% styrenephenol polyoxyethylene ether, 2% calcium dodecylbenzenesulfonate, 10% DMF, and methyl oleate makes up the balance;

[0036] Preparation method: Same as Preparation Example 3.

[0037] Preparation Example 5: 21% sulfiflumin·lufenuron suspension (6:1)

[0038] Formula composition: 18% sulfiflumin, 3% lufenuron, 2% Guerbet alcohol polyoxyethylene ether, 3% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 2% tristyrylphenol ethoxylate phosphate, 1% sodium salt of polycarboxylate, 1.5% magnesium aluminum silicate, 0.2% carboxyethyl cellulose, 1% sodium sorbate, 5% ethylene glycol, 0.5% silicone oil, and deionized water to make up the balance;

[0039] Preparation method: Same as Preparation Example 1.

[0040] Preparation Example 6: 30% sulfiflumin·lufenuron water dispersible granules (3:2)

[0041] Formula composition: 18% sulfiflumin, 12% lufenuron, 10% dispersant NNO, 2% sodium dodecyl sulfate, 6% sodium lignin sulfonate, 30% starch, and light calcium carbonate to make up the balance;

[0042] Preparation method: Same as Preparation Example 2.

[0043] Preparation Example 7: 27% sulfiflumin·fluanidazole suspension (4:5)

[0044] Formula composition: 12% sulfiflumin, 15% fluopicolide, 2% isotridecyl alcohol polyoxyethylene ether, 4% tristyrylphenol ethoxylate phosphate, 1% lignin sulfonate, 3% alkyl aryl polyoxyethylene ether polyoxypropylene ether, 0.25% xanthan gum, 5% glycerol, 0.1% sodium benzoate, 0.5% silicone oil, and deionized water to make up the balance;

[0045] Preparation method: Same as Preparation Example 1.

[0046] Preparation Example 8: 39% sulfiflumin·fluanidazole water dispersible granules (1:12)

[0047] Formula composition: 3% sulfiflumin, 36% fluopicolide, 8% sodium lignin sulfonate, 2% pull open powder BX, 8% naphthalene sulfonate formaldehyde condensate D425, 5% white sugar, kaolin makes up the balance;

[0048] Preparation method: Same as Preparation Example 2.

[0049] Preparation Example 9: 16% sulfiflumin·fluanidazole emulsifiable concentrate (7:1)

[0050] Formula composition: 14% sulfiflumin, 2% fluopicolide, 15% EO / PO block copolymer, 15% acetophenone, 10% N-octylpyrrolidone, 1% calcium dodecylbenzenesulfonate, and trimethylbenzene makes up the balance;

[0051] Preparation method: Same as Preparation Example 3.

[0052] The preparation examples prepared above have been tested and found to meet the quality and technical indicators required for the corresponding preparations, and the preparations prepared are qualified preparations recognized in the art.

[0053] Example 1: Indoor biological activity assay test

[0054] Test basis: The test refers to NY / T 1154.12-2008 "Guidelines for Indoor Bioassay Tests of Pesticides Insecticides Part 12: Spider Mite Slide Dipping Method".

[0055] Test targets: Two-spotted spider mite (Tetranychus urticae Koch) and cinnabarinus spider mite (Tetranychus cinnabarinus), and nymphs with the same physiological state were selected.

[0056] Test agents: sulfiflumin technical, etoxazole technical, lufenuron technical, fluazifop technical, provided by the Group’s R&D Center.

[0057] Test preparation: Cut the double-sided tape into 2 cm long pieces and stick them on one end of the glass slide. Select healthy mites and stick their backs on the double-sided tape (do not stick the mite legs, antennae and mouthparts). Place 30 mites on each slide and put them in a container with a wet sponge pad, cover it with a lid and place it at 25±1℃. After 2 hours, examine under a microscope, remove dead and injured individuals, and make up to 30 mites on each slide.

[0058] Drug preparation: The test drug was dissolved in a suitable solvent, and each single agent and each group of mixed agents were prepared into 5 series of mass concentration gradients according to the purpose of the mixture and the activity of the drug.

[0059] Chemical treatment: Immerse the slide in the chemical solution and shake it gently for 5 seconds before taking it out. Use filter paper to absorb the excess chemical solution, place it in a white porcelain plate with a wet sponge, and cover it with a plastic film with good light transmittance. Repeat each treatment 4 times, and set a treatment without chemical (including all organic solvents and emulsifiers) as a blank control.

[0060] Feeding and observation: The container containing the test insects was placed at a temperature of (25±1)℃ and a photoperiod of L:D=(16:8)h for feeding and observation.

[0061] Experimental investigation: Conduct microscopic examination 48 hours after treatment to check the mortality of test insects, and record the total number of insects and the number of dead insects respectively.

[0062] According to the survey data, calculate the mortality rate of each treatment. Calculate according to the following formula:

[0063]

[0064] Where:

[0065] P——mortality rate, in percentage (%);

[0066] K——indicates the number of dead insects, in units of heads;

[0067] N——represents the total number of insects treated, in heads.

[0068]

[0069] Where:

[0070] P1——adjusted mortality rate, in percentage (%);

[0071] P t ——Treatment mortality rate, expressed as percentage (%);

[0072] P0——blank control mortality rate, in percentage (%).

[0073] If the control mortality rate is less than 5%, no correction is required; if the control mortality rate is between 5% and 20%, correction should be made according to formula (2); if the control mortality rate is greater than 20%, the test needs to be repeated.

[0074] Analyze using the DPS statistical analysis system to find the LC 50 Value, to evaluate the activity of the test agent on the biological test material.

[0075] The co-toxicity coefficient (CTC value) of the mixture is calculated according to formula (3), formula (4) and formula (5):

[0076]

[0077] Where:

[0078] ATI——Actual Toxicity Index of Mixture;

[0079] S——LC of standard acaricide 50 , the unit is milligrams per liter (mg / L);

[0080] M——LC of the mixture 50 , the unit is milligrams per liter (mg / L).

[0081] TTI=TI A ×P A +TI B ×P B

[0082] Where:

[0083] TTI – Theoretical Toxicity Index of Mixtures;

[0084] TI A——A: toxicity index of the agent;

[0085] P A ——The percentage of agent A in the mixture, in percentage (%);

[0086] TI B ——Toxicity index of agent B;

[0087] P B ——The percentage of agent B in the mixture, in percentage (%).

[0088]

[0089] Where:

[0090] CTC – Co-toxicity coefficient;

[0091] ATI——Actual Toxicity Index of Mixture;

[0092] TTI - Theoretical Toxicity Index of Mixture.

[0093] The co-toxicity coefficient of the combination CTC ≥ 120 shows a synergistic effect; CTC ≤ 80 shows an antagonistic effect; 80 < CTC < 120 shows an additive effect.

[0094] The results of the indoor toxicity test are shown in the following table:

[0095] Table 1 Results of the indoor biological activity test of sulfiflumin and etoxazole mixed with two-spotted spider mite

[0096] Test drug Virulence regression equation <![CDATA[LC 50 (mg / L)]]> Co-toxicity coefficient Sulfiflumin(A) y=5.4740+1.5962x 0.5047 / Ethoxazole (B) y=3.9338+1.5138x 5.0615 / A:B=1:50 y=4.0496+1.5161x 4.2352 101.535 A:B=1:45 y=4.2414+1.4151x 3.4358 123.146 A:B=1:35 y=4.2959+1.6452x 2.6789 151.055 A:B=1:25 y=4.4364+1.5463x 2.3144 162.327 A:B=1:10 y=4.6920+1.4960x 1.6065 173.037 A:B=1:5 y=4.9408+1.2350x 1.1167 180.955 A:B=5:1 y=5.8459+1.8599x 0.3509 169.221 A:B=10:1 y=5.8399+1.8213x 0.3458 158.961 A:B=25:1 y=5.6494+1.5785x 0.3878 134.812 A:B=35:1 y=5.5827+1.5207x 0.4138 125.096 A:B=45:1 y=5.5198+1.5875x 0.4705 109.410

[0097] The results of the indoor biological test show that the compounding of sulfiflumin and etoxazole in a suitable mass ratio has an excellent control effect on two-spotted spider mites. The mass ratio of sulfiflumin to etoxazole is 1:45 to 35:1, and the co-toxicity coefficient is greater than 120, showing a synergistic effect.

[0098] Table 2 Results of the indoor biological activity test of sulfiflumin and lufenuron mixed with two-spotted spider mite

[0099]

[0100]

[0101] The results of indoor test show that when sulfiflumin and lufenuron are combined in a mass ratio of 20:1 to 1:35, the co-toxicity coefficient to two-spotted spider mites is greater than 120, showing a synergistic effect.

[0102] Table 3 Results of the indoor biological activity test of sulfiflumin and fluopicolide on Tetranychus urticae

[0103] Test drug Virulence regression equation <![CDATA[LC 50 (mg / L)]]> Co-toxicity coefficient Sulfiflumin(A) y=5.4740+1.5962x 0.5047 / Fluoxetine(B) y=3.8921+1.7595x 4.2626 / A:B=1:45 y=4.2510+1.4573x 3.2658 112.339 A:B=1:25 y=4.3735+1.5011x 2.6142 126.756 A:B=1:15 y=4.5345+1.5005x 2.0428 142.398 A:B=1:7 y=4.7835+1.4748x 1.4022 157.450 A:B=1:3 y=5.0596+1.5926x 0.9174 162.379 A:B=1:1 y=5.3465+1.4701x 0.5811 155.315 A:B=3:1 y=5.5544+1.6337x 0.4578 141.412 A:B=7:1 y=5.5391+1.4118x 0.4151 136.643 A:B=15:1 y=5.4453+1.1766x 0.4183 127.691 A:B=25:1 y=5.3968+1.2876x 0.4918 106.225 A:B=45:1 y=5.2517+0.9649x 0.5484 93.830

[0104] The results of indoor biological tests show that the combination of sulfiflumin and fluopicolide, at a mass ratio of 1:25 to 15:1, exhibits a synergistic effect against two-spotted spider mites.

[0105] Table 4 Results of the indoor biological activity test of sulfiflumin and etoxazole mixed with cinnabarinus spider mite

[0106] Test drug Virulence regression equation <![CDATA[LC 50 (mg / L)]]> Co-toxicity coefficient Sulfiflumin(A) y=5.1145+1.3081x 0.8175 / Ethoxazole (B) y=3.7663+1.4953x 6.6842 / A:B=1:50 y=4.0485+1.4018x 4.7727 122.775 A:B=1:45 y=4.2043+1.3369x 3.9372 146.859 A:B=1:35 y=4.2168+1.3826x 3.6854 151.224 A:B=1:25 y=4.3367+1.3116x 3.2045 163.468 A:B=1:8 y=4.6126+1.3888x 1.9008 195.647 A:B=1:5 y=4.6697+1.4312x 1.7014 178.895 A:B=5:1 y=5.3287+1.4421x 0.5916 161.862 A:B=8:1 y=5.2649+1.1412x 0.5860 154.580 A:B=25:1 y=5.1907+1.1607x 0.6851 123.495 A:B=35:1 y=5.1921+1.3239x 0.7160 117.029 A:B=45:1 y=5.0652+1.0736x 0.8695 95.848

[0107] The results of indoor biological tests show that the combination of sulfiflumin and etoxazole, at a mass ratio of 1:45 to 25:1, exhibits a synergistic effect against Tetranychus cinnabarinus.

[0108] Table 5 Results of the indoor biological activity test of sulfiflumin and lufenuron mixed with cinnabarin spider mite

[0109] Test drug Virulence regression equation <![CDATA[LC 50 (mg / L)]]> Co-toxicity coefficient sulfiflumin(A) y=5.1145+1.3081x 0.8175 / Lufenuron(B) y=3.1179+1.6172x 14.5820 / A:B=35:1 y=5.2414+1.4879x 0.6883 121.969 A:B=20:1 y=5.3282+1.4803x 0.6002 142.615 A:B=10:1 y=5.4303+1.7083x 0.5599 159.714 A:B=8:1 y=5.3718+1.4601x 0.5563 164.172 A:B=4:1 y=5.4257+1.7504x 0.5712 176.427 A:B=1:1 y=5.0283+1.3805x 0.9538 162.320 A:B=1:4 y=4.5690+1.3264x 2.1132 157.996 A:B=1:8 y=4.1602+1.5130x 3.5897 141.499 A:B=1:10 y=4.1724+1.3251x 4.2127 136.780 A:B=1:20 y=3.8738+1.3203x 7.1290 113.524 A:B=1:35 y=3.7466+1.2794x 9.5425 104.116

[0110] The results of indoor biological tests showed that the combination of sulfiflumin and lufenuron, at a mass ratio of 1:10 to 35:1, showed a synergistic effect against Tetranychus cinnabarinus.

[0111] Table 6 Results of the indoor biological activity test of sulfiflumin and fluopicolide mixed with cinnabarinus spider mite

[0112] Test drug Virulence regression equation <![CDATA[LC 50 (mg / L)]]> Co-toxicity coefficient sulfiflumin(A) y=5.1145+1.3081x 0.8175 / Fluoxetine(B) y=3.5223+1.7130x 7.2884 / A:B=1:40 y=3.8874+1.5416x 5.2694 115.933 A:B=1:30 y=4.0599+1.5073x 4.2047 138.082 A:B=1:15 y=4.3127+1.3569x 3.2101 151.899 A:B=1:7 y=4.6180+1.4351x 1.8456 198.502 A:B=1:3 y=4.7781+1.4987x 1.4062 173.994 A:B=1:1 y=5.0109+1.4576x 0.9829 149.568 A:B=3:1 y=5.1906+1.4383x 0.7370 142.567 A:B=7:1 y=5.2521+1.4608x 0.6721 136.818 A:B=15:1 y=5.2297+1.5358x 0.7087 122.129 A:B=30:1 y=5.1192+1.5014x 0.8330 101.033 A:B=40:1 y=5.0074+1.2794x 0.9867 84.686

[0113] The results of indoor biological tests showed that the combination of sulfiflumin and fluopicolide, at a mass ratio of 1:30 to 15:1, showed a synergistic effect against Tetranychus cinnabarinus.

[0114] Example 2: Field efficacy test of acaricidal composition against two-spotted spider mites

[0115] Test location: This test was conducted in Shaojiazhuang Village, Mancheng District, Baoding City, Hebei Province. The soil fertility of the test site is relatively high, and the cultivation and management conditions are good. The water and fertilizer management of all test plots is uniform and consistent, which is in line with local scientific agricultural practices.

[0116] Test target: Strawberry two-spotted spider mite.

[0117] Experimental crop: Strawberry.

[0118] Experimental design: There are 8 treatments in total, with clean water as the blank control. Each treatment is repeated 4 times, and each plot is 30m2. 2 , using random block arrangement, with two rows of strawberries between each plot.

[0119] Test method: A 3WBD-20 backpack electric sprayer was used to evenly spray the liquid on the front and back of the strawberry leaves. The application time was March 22, 2023, and the total application was 1 time.

[0120] Survey method: The test investigated the base number of mites before applying the pesticide, and the insect population density was investigated on the 3rd and 10th days after applying the pesticide. During the investigation, a handheld magnifying glass was used to observe and record the number of live mites on the front and back of the leaves. Five sampling points were taken in each plot, one plant was fixed at each point, and five leaves with mites were fixed on each plant to investigate the number of mites.

[0121] Calculation method of drug efficacy:

[0122]

[0123] Results and analysis:

[0124] Table 7 Field efficacy test results of the acaricidal composition against two-spotted spider mites

[0125]

[0126] From the field efficacy test in Table 7, it can be seen that the protective effects of 27% sulfiflumin·ethoxazole suspension (1:8), 21% sulfiflumin·lufenuron suspension (6:1), and 16% sulfiflumin·flufenicol emulsifiable concentrate (7:1) against two-spotted spider mites were 85.53%, 81.00%, and 80.15% 3 days after application, and the protective effects were 93.27%, 92.52%, and 89.44% respectively 14 days after application.

[0127] Example 3: Field efficacy test of acaricidal composition against Tetranychus cinnabarinus

[0128] Test location: The test was conducted in a vegetable greenhouse in Shouguang City, Weifang City, Shandong Province. The soil layer of the test site was deep and the soil fertility was above average. All test plots were in line with local conventional agricultural practices.

[0129] Test target: Tetranychus cinnabarinus.

[0130] Experimental crops: Eggplant.

[0131] Experimental design: Each plot of the experimental site is 20m 2All test plots were arranged in random blocks, and each treatment was repeated 4 times. The test was carried out in the early stage of the occurrence of cinnabarinus spider mites. Each pesticide treatment was diluted to a certain concentration during the application, and the whole eggplant plant was sprayed with a Gongnong-16 sprayer to ensure that the front and back of each leaf were evenly sprayed.

[0132] Survey method: 5 eggplant plants were fixed in each plot, and 3 leaves were surveyed for each eggplant plant. The base number of spider mites was surveyed before spraying, and the number of surviving mites was surveyed 3d, 7d, and 15d after spraying, and the mite population reduction rate and control effect were calculated.

[0133] Calculation method of drug efficacy:

[0134]

[0135] Field efficacy test results and analysis:

[0136] Table 8 Field efficacy test results of the acaricide composition against Tetranychus cinnabarinus

[0137]

[0138] The results of the field efficacy test show that the combination of sulfiflumin with etoxazole, lufenuron or flutoxifen has a good control effect on cinnabarin spider mites. 42% sulfiflumin·etoxazole water dispersible granules (5:1), 30% sulfiflumin·lufenuron water dispersible granules (3:2), and 27% sulfiflumin·flutoxifen suspension (4:5) showed good rapid effect on cinnabarin spider mites 3 days after the application. 15 days after the application, the control effects of 42% sulfiflumin·etoxazole water dispersible granules (5:1), 30% sulfiflumin·lufenuron water dispersible granules (3:2), and 27% sulfiflumin·flutoxifen suspension (4:5) on cinnabarin spider mites were 93.59%, 95.64%, and 92.85%, respectively, with a long lasting effect.

[0139] Example 4: Field test of the efficacy of the acaricidal composition against citrus red spider mites

[0140] Test location: Citrus orchard in Qingcao Village, Qingjiang Town, Zixing City, Hunan Province. The water, fertilizer conditions and cultivation management are relatively consistent. The test crop is Dongjiang mandarin orange, which is growing normally.

[0141] Experimental design: In this experiment, 7 pesticide treatments and 1 clear water control were set up. The pesticide treatments were: 16% sulfiflumin·etoxazole EC (1:3), 16% sulfiflumin·flufenac EC (7:1), 12% sulfiflumin·lufenac EC (1:2), 20% etoxazole SC, 22% lufenac EC, 21% flufenac SC, and 20% sulfiflumin water-dispersible granules.

[0142] Experimental plot setting: 3 trees per treatment, repeated 4 times, randomly arranged. Protective rows were set up around the experimental plots. During the experiment, no pesticides or water were applied to the protective rows, and routine management was carried out.

[0143] Application time: May 13, 2023. The weather was cloudy and breezy when the pesticide was applied. The leaves were sprayed evenly. When spraying, the front and back of the leaves were evenly stained with the liquid, and it was best to just start dripping.

[0144] Survey method: Survey the base number of mites before drug application, and survey the number of live mites 3d, 8d, and 14d after drug application. Mark the tender shoots of each tree in the east, south, west, north, and center of each plot, survey the number of active mites on 25 leaves of each tree, and directly observe the leaf surface with a handheld magnifying glass to count the number of mites.

[0145] Calculation method of drug efficacy:

[0146]

[0147] Field efficacy test results and analysis:

[0148] Table 9 Field efficacy test results of acaricide composition against citrus red spider mites

[0149]

[0150] The test results in Table 9 show that the acaricidal composition of the present invention has a good control effect on citrus red spider mites, and its quick-acting effect and lasting effect are significantly better than those of the single-dose control.

[0151] Although the present invention has been described in detail above with general descriptions and specific implementation schemes, it is obvious to those skilled in the art that some modifications or improvements can be made on the basis of the present invention. Therefore, these modifications or improvements made without departing from the spirit of the present invention are within the scope of protection claimed by the present invention.

Claims

1. A miticide, characterized in that: The acaricide comprises active ingredient A and active ingredient B, wherein the active ingredient A is a compound of formula I: The active ingredient B is flutosan.

2. The acaricide according to claim 1, characterized in that The mass ratio of active ingredient A to active ingredient B in the acaricide is 1:50 to 45:1; Preferably, the mass ratio of the active ingredient A to the active ingredient B is 1:45 to 35:

1.

3. The acaricide according to claim 1, characterized in that The mass ratio of the active ingredient A to the active ingredient B is 1:30 to 15:1; Preferably, the mass ratio of the active ingredient A to the active ingredient B is 1:25 to 15:

1.

4. The acaricide according to claim 1, characterized in that Based on the total weight of the acaricide being 100 wt %, the total weight of the active ingredient A and the active ingredient B accounts for 0.1 wt % to 80 wt % of the total weight of the fungicide composition.

5. The acaricide according to claim 1, characterized in that The acaricide contains auxiliary ingredients permitted in pesticides in addition to active ingredients, and the auxiliary ingredients are selected from one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, preservatives, stabilizers, synergists, binders, fillers or carriers.

6. The acaricide according to claim 1, characterized in that The acaricide can be prepared into a pesticide acceptable formulation, which is a solid formulation or a liquid formulation.

7. The acaricide according to claim 6, characterized in that The solid preparation is a granule, a wettable powder, an oil-dispersible powder, an emulsion, a water-dispersible granule, an emulsion, a water-dispersible tablet, a soluble powder, a soluble tablet or a soluble granule; the liquid preparation is a soluble solution, a soluble gel, an oil, a film-spreading oil, an emulsifiable concentrate, a latex, a dispersible liquid, an ointment, an aqueous emulsion, an oil emulsion, a microemulsion, a fat, a suspension, a microcapsule suspension, an oil suspension, a dispersible oil suspension or a suspoemulsion.

8. The acaricide according to claim 7, characterized in that The solid preparation is a wettable powder or a water-dispersible granule, and the liquid preparation is an emulsifiable concentrate, an aqueous emulsion, a microemulsion, a suspension, or a dispersible oil suspension.

9. Use of the acaricide according to any one of claims 1 to 8 for controlling harmful mites of crops and garden plants.

10. The use according to claim 9, characterized in that The plant harmful mites are Tetranychus cinnabarinus, Tetranychus urticae and Panonychus citri.

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