Medicinal and edible health care product containing pawpaw and application of medicinal and edible health care product

Abstract

The invention discloses a health-care product with homology of medicine and food. The health-care product comprises the following raw materials in parts by mass: 15-20 parts of a papaya extract, 8-10 parts of a chicory root extract, 5-6 parts of a compound fermentation extract, 5-7 parts of a dogwood extract, 3-6 parts of turmeric and 2-3 parts of plantain herb. The invention aims to solve the problems of poor effect, single component and the like of the health care product in the prior art, the used raw materials are natural plant extracts with homology of medicine and food, and the health care product with homology of medicine and food realizes the comprehensive health care function through various mechanisms (reducing uric acid, resisting inflammation, easing pain, resisting oxidation and regulating metabolism and immunity).

Description

Technical Field

[0001] The invention relates to the technical field of health care products, in particular to a health care product containing papaya which is both a medicine and a food and an application thereof. Background Art

[0002] "Medicine and food have the same origin" means that some foods have the dual attributes of medicine and food. They can be used as ingredients for daily diet and as medicinal materials for medical care. This concept originated from ancient Chinese medicine, which emphasizes regulating body functions, preventing and treating diseases through natural foods. Common ingredients for medicine and food have the same origin include yam, wolfberry, astragalus, red dates, etc. As an innovative product that combines natural ingredients and traditional Chinese medicine theory, medicine and food health products have shown great potential in the field of health and wellness.

[0003] Food and medicine health products usually contain a variety of natural plant extracts or Chinese medicinal materials, which are rich in nutrition and pharmacological activity. Food and medicine health products have many advantages, but they also face some technical challenges in practical applications: for example, the ingredients of food and medicine raw materials are complex, and there are many types of effective ingredients. How to extract the effective ingredients is a technical problem, which puts high demands on the selection of raw material types and the determination of preparation processes. In addition, the efficacy evaluation of existing health products mainly relies on traditional Chinese medicine theory and experience, and lacks modern scientific quantitative indicators and experimental data support. For example, although the health effects of certain ingredients are theoretically valid, the actual efficacy still needs to be verified by quantitative experimental data.

[0004] In view of this, the present invention is proposed. Summary of the invention

[0005] The purpose of the present invention is to provide a food and medicine health product containing papaya and its application, so as to solve the problems existing in the above-mentioned prior art.

[0006] To achieve the above object, the present invention provides the following solutions:

[0007] The present invention provides a health-care product having both medicinal and edible properties, the raw materials of which include the following components in proportions by weight:

[0008] 15-20 parts of papaya extract, 8-10 parts of chicory root extract, 5-6 parts of complex fermentation extract, 5-7 parts of cornus officinalis extract, 3-6 parts of turmeric and 2-3 parts of plantain.

[0009] Furthermore, the preparation method of the papaya extract comprises the following steps:

[0010] The papaya extract is obtained by enzymolysis using a composite enzyme, the obtained enzymolysis product is centrifuged and the supernatant is removed to obtain the papaya extract;

[0011] The complex enzyme is a compound mixture of cellulase and pectinase in a mass ratio of 1-2:1-3; the temperature of the enzymolysis is 45-50° C. and the time is 2-3 hours.

[0012] Furthermore, the preparation method of the chicory root extract comprises the following steps:

[0013] The dried chicory root is subjected to ethanol reflux extraction, the extract is extracted with petroleum ether, the extract is concentrated and then extracted with ethyl acetate, the ethyl acetate phase is collected and concentrated to obtain the chicory root extract.

[0014] Furthermore, the preparation method of the composite fermentation extract comprises the following steps:

[0015] The pine pollen and galangal are mixed, beta-glucanase is added for fermentation, and the composite fermentation extract is obtained.

[0016] Furthermore, the mass ratio of the pine pollen to galangal is 1:2-3.

[0017] Furthermore, the fermentation temperature is 38±2°C, and the fermentation time is 3-5 days.

[0018] Furthermore, the preparation method of the Cornus officinalis extract comprises the following steps:

[0019] (1) grinding the dried cornus officinalis pulp, adding a biological composite enzyme to carry out an enzymatic hydrolysis reaction, and after the enzymatic hydrolysis reaction is completed, inactivating the enzyme to obtain an enzymatic hydrolyzate;

[0020] (2) subjecting the enzymatic hydrolysate obtained in step (1) to ultrasonic-assisted supercritical carbon dioxide extraction to obtain the Cornus officinalis extract.

[0021] Furthermore, the biological composite enzyme is a mixture of cellulase, pectinase and hemicellulase in a mass ratio of 1-2:1-3:1-2.

[0022] Furthermore, the extraction pressure of the ultrasonic-assisted supercritical carbon dioxide extraction is 20-30MPa, and the temperature is 40-50°C; the ultrasonic frequency of the ultrasonic-assisted supercritical carbon dioxide extraction is 20-40kHz; and the CO2 flow rate is 5-10L / min.

[0023] All raw materials of the present invention exert their unique pharmacological effects and efficacies, and work synergistically to achieve the best health-care effect.

[0024] Papaya (scientific name: Carica papaya) is a tropical fruit rich in various nutrients, including vitamin C, vitamin A, potassium, dietary fiber and various antioxidants, which make papaya not only have rich nutritional value, but also have significant health care functions. The present invention extracts active ingredients from papaya, and through reasonable proportioning, can effectively alleviate joint inflammation and pain, while promoting uric acid metabolism and reducing uric acid accumulation in the body. The enzymatic hydrolysis method of the present invention can efficiently release the active ingredients in papaya, ensure the efficient retention of the active ingredients in the extract, enhance the interaction between components, and achieve health care effects.

[0025] Chicory root has the potential characteristics of lowering serum uric acid level, protecting liver, and anti-inflammatory and anti-oxidative. The present invention adopts a method combining ethanol reflux extraction, petroleum ether extraction and ethyl acetate extraction to fully extract the effective ingredients in chicory root, ensuring its anti-inflammatory, analgesic and immunomodulatory effects.

[0026] The present invention adopts ultrasound-assisted supercritical carbon dioxide extraction combined with enzymatic hydrolysis to extract the effective substances in Cornus officinalis, thereby ensuring the best performance of the anti-inflammatory, analgesic and immunoregulatory effects of the active ingredients.

[0027] By determining the raw material components and their reasonable proportions, and combining them with scientific preparation methods, the medicine-food health care product of the present invention can play an important role in the following aspects:

[0028] a. Lowering uric acid: The papaya extract, chicory root extract, composite fermentation product and plantain of the present invention can synergistically promote uric acid excretion, lower blood uric acid levels, and prevent gout attacks.

[0029] b. Anti-inflammatory and analgesic: The papaya extract, cornus officinalis extract and turmeric of the present invention act synergistically to significantly reduce joint inflammation and pain.

[0030] c. Antioxidant: The antioxidant properties of the various ingredients of the present invention work together to remove free radicals, protect cell health, and delay aging.

[0031] d. Regulate metabolism and immunity: Compound fermentation extract and Cornus officinalis extract can further improve basal immunity and ensure body health by regulating intestinal flora and immune system.

[0032] The present invention also provides a method for preparing the above-mentioned medicine-food homologous health-care product, comprising the following steps:

[0033] The raw materials are mixed according to a mass ratio, a binder is added to prepare a soft material, and then granulated and dried to obtain the medicine and food health product.

[0034] The present invention further provides the use of the above-mentioned medicine and food homologous health care product in preventing and treating gout, resisting inflammation and relieving pain, and improving immunity.

[0035] The present invention further provides a medicinal and edible composition for treating gout, wherein the raw materials include the following components in proportions by weight:

[0036] 15-20 parts of papaya extract, 8-10 parts of chicory root extract, 5-6 parts of complex fermentation extract, 5-7 parts of cornus officinalis extract, 3-6 parts of turmeric and 2-3 parts of plantain.

[0037] The present invention discloses the following technical effects:

[0038] The present invention provides a medicine-food health product and its application, aiming to solve the problems of poor effect and single ingredients of health products in the prior art. The raw materials used in the present invention are all natural plant extracts that are medicine-food, and the medicine-food health product achieves comprehensive health functions through multiple mechanisms (reducing uric acid, anti-inflammatory and analgesic, anti-oxidation, regulating metabolism and immunity). DETAILED DESCRIPTION

[0039] Various exemplary embodiments of the present invention will now be described in detail. This detailed description should not be considered as limiting the present invention, but should be understood as a more detailed description of certain aspects, features, and embodiments of the present invention.

[0040] It should be understood that the terms described in the present invention are only for describing a particular embodiment and are not intended to limit the present invention. In addition, for the numerical range in the present invention, it should be understood that each intermediate value between the upper and lower limits of the scope is also specifically disclosed. The intermediate value in any stated value or stated range, and each smaller range between any other stated value or intermediate value in the described range is also included in the present invention. The upper and lower limits of these smaller ranges can be independently included or excluded in the scope.

[0041] Unless otherwise indicated, all technical and scientific terms used herein have the same meanings as those generally understood by those skilled in the art. Although the present invention describes only preferred methods and materials, any methods and materials similar or equivalent to those described herein may also be used in the implementation or testing of the present invention. All documents mentioned in this specification are incorporated by reference to disclose and describe the methods and / or materials associated with the documents. In the event of a conflict with any incorporated document, the content of this specification shall prevail.

[0042] It will be apparent to those skilled in the art that various modifications and variations may be made to the specific embodiments of the present invention description without departing from the scope or spirit of the present invention. Other embodiments derived from the present invention description will be apparent to those skilled in the art. The present invention description and examples are exemplary only.

[0043] The words “include,” “including,” “have,” “contain,” etc. used in this document are open-ended terms, meaning including but not limited to.

[0044] Example 1

[0045] The medicinal and edible health care product of this embodiment includes the following raw material components in proportions by weight:

[0046] 18 parts of papaya extract, 9 parts of chicory root extract, 5 parts of complex fermentation extract, 6 parts of cornus officinalis extract, 4 parts of turmeric and 3 parts of plantain.

[0047] The preparation method of the food-medicine health product of this embodiment comprises the following steps:

[0048] Step S1. Preparation of papaya extract:

[0049] (1) mashing papaya and putting it into an enzymolysis tank, then adding 60 times of water by weight, heating to 50° C., and then adding 0.3% of the weight of papaya (a mixture of cellulase and pectinase in a mass ratio of 1:3); after adding the complex enzyme, enzymolysis is performed at 50° C. for 2 hours to obtain an enzymolysis product; after the enzymolysis is completed, heating to 90° C. to terminate the enzyme activity and prevent excessive decomposition;

[0050] (2) centrifuging the enzymatic hydrolysis product at a centrifugal speed of 20,000 rpm, removing the supernatant after centrifugation to obtain a centrifuged product, and drying to obtain a papaya extract.

[0051] Step S2. Preparation of chicory root extract:

[0052] (1) drying and crushing chicory roots, extracting them with ethanol reflux, collecting the extract, extracting them with petroleum ether for three times, and combining the petroleum ether phases for concentration;

[0053] (2) The concentrated solution of step (1) was extracted three times with ethyl acetate, the ethyl acetate extracts were combined, concentrated under vacuum to remove the solvent, and dried to obtain chicory root extract.

[0054] Step S3. Preparation of composite fermentation extract:

[0055] Pine pollen and galangal were compounded in a mass ratio of 1:2, and then β-glucanase was added and fermented at 38±2°C for 3 days to obtain a composite fermentation extract.

[0056] Step S4. Preparation of Cornus officinalis extract:

[0057] (1) The dried cornus officinalis pulp was crushed, and a biocomplex enzyme (a mixture of cellulase, pectinase and hemicellulase in a mass ratio of 2:3:2) was added at 0.3% of the mass of the cornus officinalis pulp, and the enzymatic hydrolysis reaction was carried out at 45°C for 2 hours, and stirring was maintained during the reaction to ensure that the enzyme was fully in contact with the raw material. After the enzymatic hydrolysis was completed, the enzyme activity was terminated by heating to 90°C to prevent excessive decomposition.

[0058] (2) concentrating and drying the enzymatic hydrolyzate;

[0059] (3) placing the enzymatic hydrolysis product obtained in step (2) in a supercritical carbon dioxide extraction device and equipping it with an ultrasonic generator for supercritical carbon dioxide extraction, setting the extraction pressure to 25 MPa, the temperature to 45° C., the CO2 flow rate to 8 L / min, and simultaneously turning on ultrasonic assistance (frequency 30 kHz), treating for 1.5 hours, and freeze-drying to obtain a Cornus officinalis extract.

[0060] Step S5. Preparation of food and medicine health products

[0061] (1) Place the above raw materials in a mixer according to the mass ratio and stir for 10 minutes to ensure that all ingredients are evenly mixed;

[0062] (2) adding dextrin as an adhesive to the mixed powder of step (1) to prepare a soft material;

[0063] (3) using an extrusion spheronization machine to form particles;

[0064] (4) Drying the granules in a drying oven at 50° C. until the moisture content reaches 5%, thereby obtaining a medicine-food health product.

[0065] Example 2

[0066] The medicinal and edible health care product of this embodiment includes the following raw material components in the following mass proportions:

[0067] 15 parts of papaya extract, 10 parts of chicory root extract, 5 parts of complex fermentation extract, 5 parts of cornus officinalis extract, 3 parts of turmeric and 3 parts of plantain.

[0068] The preparation method of the food-medicine health product of this embodiment comprises the following steps:

[0069] Step S1. Preparation of papaya extract:

[0070] (1) mashing papaya and putting it into an enzymolysis tank, then adding 50 times of water by weight, heating to 45° C., and then adding 0.3% of the weight of papaya (a mixture of cellulase and pectinase in a mass ratio of 2:3); after adding the complex enzyme, enzymolysis is performed at 45° C. for 2 hours to obtain an enzymolysis product; after the enzymolysis is completed, heating to 90° C. to terminate the enzyme activity and prevent excessive decomposition;

[0071] (2) centrifuging the enzymatic hydrolysis product at a centrifugal speed of 20,000 rpm, removing the supernatant after centrifugation to obtain a centrifuged product, and drying to obtain a papaya extract.

[0072] Step S2. Preparation of chicory root extract:

[0073] (1) drying and crushing chicory roots, extracting them with ethanol reflux, collecting the extract, extracting them with petroleum ether for three times, and combining the petroleum ether phases for concentration;

[0074] (2) The concentrated solution of step (1) was extracted three times with ethyl acetate, the ethyl acetate extracts were combined, and the solvent was removed by vacuum concentration to obtain chicory root extract.

[0075] Step S3. Preparation of composite fermentation extract:

[0076] Pine pollen and galangal were compounded in a mass ratio of 1:2, and then β-glucanase was added and fermented at 38±2°C for 5 days to obtain a composite fermentation extract.

[0077] Step S4. Preparation of Cornus officinalis extract:

[0078] (1) The dried cornus officinalis pulp was crushed, and a biological composite enzyme (a mixture of cellulase, pectinase and hemicellulase in a mass ratio of 2:1:1) was added at 0.2% of the mass of the cornus officinalis pulp, and the enzymatic hydrolysis reaction was carried out at 45°C for 2 hours, and stirring was maintained during the reaction to ensure that the enzyme was fully in contact with the raw material. After the enzymatic hydrolysis was completed, the enzyme activity was terminated by heating to 90°C to prevent excessive decomposition.

[0079] (2) concentrating and drying the enzymatic hydrolyzate;

[0080] (3) placing the enzymatic hydrolysis product obtained in step (2) in a supercritical carbon dioxide extraction device and equipping it with an ultrasonic generator for supercritical carbon dioxide extraction, setting the extraction pressure to 20 MPa, the temperature to 40° C., the CO2 flow rate to 10 L / min, and simultaneously turning on ultrasonic assistance (frequency 35 kHz), treating for 2 hours, and freeze-drying to obtain a Cornus officinalis extract.

[0081] Step S5. Preparation of food and medicine health products

[0082] (1) Place the above raw materials in a mixer according to the mass ratio and stir for 15 minutes to ensure that all ingredients are evenly mixed;

[0083] (2) adding adhesive starch to the mixed powder of step (1) to prepare a soft material;

[0084] (3) using an extrusion spheronization machine to form particles;

[0085] (4) Drying the granules in a drying oven at 50° C. until the moisture content reaches 5%, thereby obtaining a medicine-food health product.

[0086] Example 3

[0087] The medicinal and edible health care product of this embodiment includes the following raw material components in the following mass proportions:

[0088] 15 parts of papaya extract, 8 parts of chicory root extract, 5 parts of complex fermentation extract, 7 parts of cornus officinalis extract, 4 parts of turmeric and 2 parts of plantain.

[0089] The preparation method of the food-medicine health product of this embodiment comprises the following steps:

[0090] Step S1. Preparation of papaya extract:

[0091] (1) mashing papaya and putting it into an enzymolysis tank, then adding 50 times of water by weight, heating to 45° C., and then adding 0.3% of the weight of papaya (a mixture of cellulase and pectinase in a mass ratio of 1:1); after adding the complex enzyme, enzymolysis is performed at 50° C. for 2 hours to obtain an enzymolysis product; after the enzymolysis is completed, heating to 90° C. to terminate the enzyme activity and prevent excessive decomposition;

[0092] (2) centrifuging the enzymatic hydrolysis product at a centrifugal speed of 20,000 rpm, removing the supernatant after centrifugation to obtain a centrifuged product, and drying to obtain a papaya extract.

[0093] Step S2. Preparation of chicory root extract:

[0094] (1) drying and crushing chicory roots, extracting them with ethanol reflux, collecting the extract, extracting them with petroleum ether for three times, and combining the petroleum ether phases for concentration;

[0095] (2) The concentrated solution of step (1) was extracted three times with ethyl acetate, the ethyl acetate extracts were combined, and the solvent was removed by vacuum concentration to obtain chicory root extract.

[0096] Step S3. Preparation of composite fermentation extract:

[0097] Pine pollen and galangal were compounded in a mass ratio of 1:2, and then β-glucanase was added and fermented at 38±2°C for 5 days to obtain a composite fermentation extract.

[0098] Step S4. Preparation of Cornus officinalis extract:

[0099] (1) The dried cornus officinalis pulp was crushed, and a biological composite enzyme (a mixture of cellulase, pectinase and hemicellulase in a mass ratio of 2:1:1) was added at 0.2% of the mass of the cornus officinalis pulp, and the enzymatic hydrolysis reaction was carried out at 45°C for 2 hours, and stirring was maintained during the reaction to ensure that the enzyme was fully in contact with the raw material. After the enzymatic hydrolysis was completed, the enzyme activity was terminated by heating to 90°C to prevent excessive decomposition.

[0100] (2) concentrating and drying the enzymatic hydrolyzate;

[0101] (3) placing the enzymatic hydrolysis product obtained in step (2) in a supercritical carbon dioxide extraction device and equipping it with an ultrasonic generator for supercritical carbon dioxide extraction, setting the extraction pressure to 25 MPa, the temperature to 45° C., the CO2 flow rate to 8 L / min, and simultaneously turning on ultrasonic assistance (frequency 35 kHz), treating for 2 hours, and freeze-drying to obtain a Cornus officinalis extract.

[0102] Step S5. Preparation of food and medicine health products

[0103] (1) Place the above raw materials in a mixer according to the mass ratio and stir for 15 minutes to ensure that all ingredients are evenly mixed;

[0104] (2) adding a binder such as dextrin to the mixed powder of step (1) to prepare a soft material;

[0105] (3) using an extrusion spheronization machine to form particles;

[0106] (4) Drying the granules in a drying oven at 50° C. until the moisture content is 5%, thereby obtaining a health product having both medicinal and edible properties.

[0107] Comparative Example 1

[0108] The only difference from Example 1 is that the papaya extract is replaced by an equal mass of dry papaya powder.

[0109] Comparative Example 2

[0110] The only difference from Example 1 is that step S4 is used to extract the chicory root extract.

[0111] Comparative Example 3

[0112] The only difference from Example 1 is that the chicory root extract is replaced by an equal mass of dried chicory root.

[0113] Comparative Example 4

[0114] The only difference from Example 1 is that the mass parts of the papaya extract were adjusted to 25 parts.

[0115] Effect verification example 1

[0116] 1. Experimental subjects

[0117] Sample selection: 240 patients with mild to moderate gout, aged 45-65 years, were selected.

[0118] Experimental grouping: The patients were randomly divided into 8 groups, 30 people in each group, and there was no significant difference in the condition and age of each group, and they were respectively used as experimental groups 1-7 and the control group; among them, the patients in the experimental groups 1-3 took the medicine and food health products of Examples 1-3 respectively, and the experimental groups 4-7 took the medicine and food health products of Comparative Examples 1-4 respectively.

[0119] The patients in the experimental groups 1-7 took 2 tablets of the food-medicine homologous health product (0.5 g / tablet, the raw materials of the food-medicine homologous health product accounted for 50%), 3 times a day.

[0120] Control group: Take the same dose of placebo (same appearance as the experimental group but without active ingredients) daily, 2 tablets each time, 3 times a day.

[0121] 2. Experimental cycle

[0122] Observation period: 12 weeks, with weekly follow-up records.

[0123] 3. Evaluation Metrics

[0124] a. Pain score: The visual analogue scale (VAS) was used to assess the degree of joint pain, ranging from 0 to 10 (0 for no pain and 10 for the most pain). The average pain scores of each group after 12 weeks are shown in Table 1.

[0125] Table 1

[0126]

[0127]

[0128] The joint pain of the patients in the experimental groups 1-3 who took the medicinal and edible health products of Examples 1-3 of the present invention was significantly alleviated, and the pain scores were greatly reduced.

[0129] b. Joint function: The Health Assessment Questionnaire (HAQ) was used to assess the patients' ability to carry out daily activities. The average values ​​of joint function scores in each group after 12 weeks are shown in Table 2.

[0130] Table 2

[0131] 0d(minutes) 12 weeks later (minutes) Experimental Group 1 1.8 0.8 Experimental Group 2 1.7 0.8 Experimental Group 3 1.8 0.7 Experimental Group 4 1.7 1.2 Experimental Group 5 1.8 1.4 Experimental Group 6 1.8 1.2 Experimental Group 7 1.7 1.3 Control group 1.7 1.5

[0132] The HAQ scores of the patients in the experimental groups 1-3 who took the medicinal and edible health products of Examples 1-3 of the present invention decreased significantly, indicating that the joint function was significantly improved; the health products of the present invention not only relieved pain, but also promoted the recovery of joint function.

[0133] c. Inflammatory indicators: C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) in serum were measured as inflammatory markers. The average values ​​of the measurement results after 12 weeks are shown in Table 3.

[0134] Table 3

[0135]

[0136]

[0137] The CRP levels and ESR of the experimental groups 1-3 taking the medicinal and edible health products of Examples 1-3 of the present invention decreased significantly, indicating that the inflammatory indicators were significantly improved.

[0138] d. Quality of life: The SF-36 quality of life scale was used to assess the patients’ quality of life. The average quality of life scores of each group after 12 weeks are shown in Table 4.

[0139] Table 4

[0140] 0d(minutes) 12 weeks later (minutes) Experimental Group 1 44 72 Experimental Group 2 43 71 Experimental Group 3 45 72 Experimental Group 4 43 61 Experimental Group 5 44 56 Experimental Group 6 44 57 Experimental Group 7 45 57 Control group 43 48

[0141] As can be seen in Table 4, after the patients’ pain was relieved and joint function improved, their overall quality of life and mental health also improved.

[0142] e. Serum uric acid concentration: The average serum uric acid concentration of each group of patients was monitored. The average serum uric acid concentration of each group of patients after 12 weeks is shown in Table 5.

[0143] Table 5

[0144]

[0145]

[0146] Effect verification example 2

[0147] Experimental subjects: Healthy adult mice were selected as experimental subjects and divided into an experimental group (taking the medicinal and edible health care products of Example 1) and a control group (not taking health care products), with 20 mice in each group.

[0148] Administration method: The above-mentioned medicine and food health products were given to the mice in the experimental group by gavage for 30 consecutive days. The dosage was converted to 50 mg / kg body weight per day based on the equivalent dose in humans.

[0149] After the experiment, the immunoglobulin levels of mice in different groups were measured as shown in Table 1:

[0150] Table 6

[0151]

[0152] The results showed that the IgG level, IgA level and IgM level in the serum of mice in the experimental group were significantly higher than those in the control group.

[0153] The above data show that the immunoglobulin level of the mice in the experimental group taking the food-medicine health product of the present invention has been significantly improved, indicating that the health product can promote the production of immunoglobulins and enhance the body's immune function.

[0154] The embodiments described above are only descriptions of the preferred modes of the present invention, and are not intended to limit the scope of the present invention. Without departing from the design spirit of the present invention, various modifications and improvements made to the technical solutions of the present invention by ordinary technicians in this field should all fall within the protection scope determined by the claims of the present invention.

Claims

1. A health product that is both a medicine and food, characterized in that: The raw materials include the following components in proportion by weight: 15-20 parts of papaya extract, 8-10 parts of chicory root extract, 5-6 parts of complex fermentation extract, 5-7 parts of cornus officinalis extract, 3-6 parts of turmeric and 2-3 parts of plantain.

2. The medicine-food health product according to claim 1, characterized in that: The preparation method of the papaya extract comprises the following steps: The papaya is enzymatically hydrolyzed by using a composite enzyme, the obtained enzymatic hydrolysis product is centrifuged, the supernatant is removed, and the papaya extract is dried to obtain the papaya extract; The complex enzyme is a compound mixture of cellulase and pectinase in a mass ratio of 1-2:1-3; the temperature of the enzymolysis is 45-50° C. and the time is 2-3 hours.

3. The medicine-food health product according to claim 1, characterized in that: The preparation method of the chicory root extract comprises the following steps: The dried chicory root is subjected to ethanol reflux extraction, the extract is extracted with petroleum ether, the extract is concentrated and then extracted with ethyl acetate, the ethyl acetate phase is collected, concentrated and dried to obtain the chicory root extract.

4. The medicine-food health product according to claim 1, characterized in that: The preparation method of the composite fermentation extract comprises the following steps: The pine pollen and galangal are mixed, beta-glucanase is added for fermentation, and the composite fermentation extract is obtained.

5. The medicine-food health product according to claim 4, characterized in that: The mass ratio of the pine pollen to galangal is 1:2-3; the fermentation temperature is 38±2° C., and the fermentation time is 3-5 days.

6. The medicine-food health product according to claim 1, characterized in that: The preparation method of the Cornus officinalis extract comprises the following steps: (1) grinding the dried cornus officinalis pulp, adding a biological composite enzyme to carry out an enzymatic hydrolysis reaction, and after the enzymatic hydrolysis reaction is completed, inactivating the enzyme to obtain an enzymatic hydrolyzate; (2) subjecting the enzymatic hydrolyzate obtained in step (1) to ultrasonic-assisted supercritical carbon dioxide extraction, and freeze-drying to obtain the Cornus officinalis extract; The biological composite enzyme is a mixture of cellulase, pectinase and hemicellulase in a mass ratio of 1-2:1-3:1-2.

7. The medicine-food health product according to claim 6, characterized in that: The extraction pressure of the ultrasonic-assisted supercritical carbon dioxide extraction is 20-30 MPa, and the temperature is 40-50° C.; the ultrasonic frequency of the ultrasonic-assisted supercritical carbon dioxide extraction is 20-40 kHz.

8. The method for preparing the food-medicine health product according to any one of claims 1 to 7, characterized in that: The following steps are involved: The raw materials are mixed according to a mass ratio, a binder is added to prepare a soft material, and then granulated and dried to obtain the medicine and food health product.

9. Use of the food-drug health product according to any one of claims 1 to 7 in preventing and treating gout, anti-inflammatory and analgesic, or improving immunity.

10. A medicinal and edible composition for treating gout, characterized in that: The raw materials include the following components in proportion by weight: 15-20 parts of papaya extract, 8-10 parts of chicory root extract, 5-6 parts of complex fermentation extract, 5-7 parts of cornus officinalis extract, 3-6 parts of turmeric and 2-3 parts of plantain.

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