Small animal medicine injection device

Abstract

The invention discloses a small animal medicine injection device, and relates to the medical field, the small animal medicine injection device comprises a base, the top of the base is fixedly connected with a medicine storage box and a protective sleeve; the protection mechanism comprises a sealing plate fixedly connected to the inner side wall of the pesticide storage box and a movable plate rotationally connected with the inner side wall of the pesticide storage box, and a plurality of through holes distributed in an annular array are formed in the top of the sealing plate and the top of the movable plate; the bearing mechanism comprises a servo motor movably arranged at the top of the base, a mounting disc arranged on the outer side wall of the output end of the servo motor in a sleeving manner, and a bearing disc fixedly connected to the output end of the servo motor and used for containing an injector. According to the medicine injection device for the small animals, the needle cylinder is inserted into the position below the liquid level, the movable sleeve and the push-pull handle are driven to move upwards, then liquid medicine is extracted into the needle cylinder, the lifting distance of the push-pull handle can be precisely controlled through the arranged servo motor and the arranged lead screw, and then precise medicine taking is achieved.

Description

Technical Field

[0001] The invention relates to the medical field, and in particular to a drug injection device for small animals. Background Art

[0002] To study the effects of drugs on gliomas, scientists use animal models that have characteristics of human gliomas. These models can be established by transplanting human glioma cells into immunodeficient mice, or using transgenic animal models. Selecting an appropriate animal model is crucial to simulating the growth environment, biological characteristics, and drug response of human gliomas. In animal models, drugs with anti-glioma activity can be screened by injecting different doses of drugs. At the same time, the effective dose and safety of the drug are studied.

[0003] After searching the publication (announcement) number: CN214017966U, an animal experiment drug injection device is disclosed, including a sleeve with a syringe inside and a handle connected to the sleeve and equipped with a motor inside. A connecting rod for pushing the drug is provided on the syringe, and the motor is used to push and pull the connecting rod to realize the injection of the syringe.

[0004] Although the above scheme can control the amount of medicine injected, the syringe and needle are recycled, and the residual liquid medicine in the needle and syringe is easy to form crystals, which can easily cause needle blockage and affect the accuracy of the injection dose. Summary of the invention

[0005] The main purpose of the present invention is to provide a small animal drug injection device, which solves the problem of recycling syringes and needles by setting up a supporting mechanism, a syringe and an injection mechanism. The residual drug solution in the needle and the syringe is prone to crystallization, which can easily cause needle blockage and affect the accuracy of the injection dose.

[0006] To achieve the above object, the technical solution adopted by the present invention is:

[0007] A drug injection device for small animals, comprising:

[0008] A base, the top of which is fixedly connected with a medicine storage box and a protective sleeve;

[0009] The protection mechanism includes a sealing plate fixedly connected to the inner wall of the medicine storage box, and a movable plate rotatably connected to the inner wall of the medicine storage box, and the tops of the sealing plate and the movable plate are both provided with a plurality of through holes distributed in a circular array;

[0010] The bearing mechanism includes a servo motor movably arranged on the top of the base, a mounting plate sleeved on the outer side wall of the servo motor output end, and a bearing plate fixedly connected to the servo motor output end for placing the syringe;

[0011] The syringe comprises a syringe penetrating the carrier plate, a piston movably arranged inside the syringe, and a push-pull handle fixedly connected to the top of the piston;

[0012] The injection mechanism comprises an electric push rod fixedly connected to the bottom of the mounting plate, a fixing sleeve fixedly connected to the output end of the electric push rod, and a connecting piece movably arranged inside the fixing sleeve for driving the push-pull handle.

[0013] Preferably, the bearing mechanism further comprises a driving motor fixedly connected to the inner side wall of the protective sleeve, a transmission plate fixedly connected to the output end of the driving motor, a hydraulic cylinder fixedly connected to the top of the transmission plate, and a horizontal plate fixedly connected to the output end of the hydraulic cylinder;

[0014] The top of the servo motor is fixedly connected to the bottom of the horizontal plate, and the mounting plate is fixedly connected to the horizontal plate via a connecting rod.

[0015] Preferably, a plurality of through holes are provided at the bottom of the carrier plate, the inner diameter of the through holes is equal to the outer diameter of the syringe, and the number of the through holes is one more than the number of syringes.

[0016] Preferably, the injection mechanism further comprises a micro motor fixedly connected to the inner top wall of the fixed sleeve, a screw rod fixedly connected to the output end of the micro motor, and a movable seat threadedly connected to the outer side wall of the screw rod;

[0017] The connecting piece is fixedly connected to the bottom of the movable seat.

[0018] Preferably, the connecting part includes a movable sleeve fixedly connected to the bottom of the movable seat, an electromagnet embedded in the movable sleeve, a storage groove opened on the outer wall of the movable sleeve, a connecting spring fixedly connected to the inner wall of the storage groove, and a locking block fixedly connected to the end face of the connecting spring. A groove is opened at the top center of the push-pull handle, and a locking groove is opened on the inner wall of the groove.

[0019] Preferably, the connecting member also includes a distance measuring sensor embedded in the locking block close to the end surface of the connecting spring, a slide groove opened at the bottom of the locking groove, and a baffle movably arranged inside the slide groove.

[0020] Preferably, the connecting member also includes a spring groove opened on the inner side wall of the locking groove, a lifting spring fixedly connected to the inner side wall of the spring groove, and a blocking column fixedly connected to the top of the lifting spring, and the baffle and the blocking column are both permanent magnets.

[0021] Preferably, the connecting member further comprises a positioning column fixedly connected to the top of the carrying plate, and a positioning hole opened at the top of the syringe, and the outer diameter of the positioning column is equal to the inner diameter of the positioning hole.

[0022] Preferably, a stirring motor is fixedly connected to the interior of the medicine storage box, and a stirring fan blade is fixedly connected to the outer side wall of the output end of the stirring motor.

[0023] Preferably, a main gear is fixedly connected to the outer side wall of the transmission plate, a driven gear is fixedly connected to the outer side wall of the movable plate, and the main gear is meshed with the driven gear.

[0024] Compared with the prior art, the present invention has the following beneficial effects:

[0025] 1. In the present invention, the syringe is inserted into the through hole, and the positioning column is passed through the positioning hole, and then the servo motor is started to drive the carrier plate to rotate, so as to leak the next through hole, and then the above operation is repeated to insert the syringe into the through hole in turn. After the insertion is completed, one of the through holes is idle, and the other through holes correspond to the fixing sleeve one by one, so as to realize the preliminary positioning of the syringe.

[0026] 2. In the present invention, the electric push rod is started to drive the fixed sleeve to move downward until the syringe is fixed under the action of the fixed sleeve and the supporting plate. At this time, the syringe is located directly above the medicine storage box, and the through holes of the sealing plate and the movable plate are overlapped. Then the hydraulic cylinder is started, and the syringe is inserted into the interior of the medicine storage box, and the syringe will be inserted below the liquid level. Then the micro motor is started to rotate forward, thereby driving the screw rod to rotate, so as to achieve the downward movement of the movable seat and the movable sleeve until the movable sleeve is inserted into the interior of the groove. At this time, the locking groove is opposite to the storage groove. Then the electromagnet is powered off. At this time, the locking block will be inserted into the locking groove under the action of the connecting spring, so that the movable sleeve is connected to the push-pull handle. By starting the micro motor to reverse, the movable sleeve and the push-pull handle are driven to move upward, and the medicine liquid is extracted into the interior of the syringe. The servo motor and the screw rod are provided to accurately control the rising distance of the push-pull handle, thereby achieving accurate medicine removal.

[0027] 3. In the present invention, the syringe is moved out of the medicine storage box by a hydraulic cylinder, and then the drive motor is started, so that the transmission plate and the syringe rotate, thereby moving the syringe to the other side of the medicine storage box. During this process, the transmission plate will drive the main gear to rotate, and then drive the driven gear meshing therewith to rotate, so as to adjust the position of the movable plate, and make the through holes on the movable plate intersect with the through holes on the sealing plate, so as to achieve the sealing effect of the medicine storage box. After that, a mouse is taken in, and the injection needle is installed on the syringe, so that the syringe is plugged into the mouse, and the micromotor is started, so as to drive the connecting piece and the push-pull handle to move downward, so as to inject a certain amount of liquid medicine into the body of the mouse.

[0028] 4. In the present invention, the electromagnet is powered to have magnetic force, thereby adsorbing the locking block and compressing the connecting spring until the locking block is completely retracted into the storage groove. At this time, the blocking column will move into the locking groove under the action of the lifting spring, thereby blocking the locking groove and preventing the reuse of the syringe. The distance measuring sensor provided therein is used to detect the moving position of the locking block to ensure that the locking block can be fully inserted into the locking groove. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0030] Figure 2 It is a schematic diagram of the internal structure of the present invention;

[0031] Figure 3 For the present invention Figure 2 A schematic diagram of the enlarged structure in the middle;

[0032] Figure 4 For the present invention Figure 3 A magnified schematic diagram of the structure B in the middle;

[0033] Figure 5 For the present invention Figure 4 A magnified schematic diagram of the C structure;

[0034] Figure 6 This is a schematic diagram of the separation structure of the sealing plate and the movable plate of the present invention;

[0035] Figure 7 It is a schematic diagram of the structure of the syringe of the present invention;

[0036] Figure 8 For the present invention Figure 7 A magnified schematic diagram of the D structure.

[0037] In the figure: 1. base; 2. medicine storage box; 201. stirring motor; 202. stirring fan blade; 203. sealing plate; 204. movable plate; 205. driven gear; 206. main gear; 3. protective sleeve; 401. drive motor; 402. transmission plate; 403. hydraulic cylinder; 404. horizontal plate; 405. servo motor; 406. mounting plate; 407. bearing plate; 501. syringe; 502. piston; 503. push-pull handle; 601. electric push rod; 602. fixed sleeve; 603. micro motor; 604. lead screw; 605. movable seat; 606. movable sleeve; 607. electromagnet; 608. connecting spring; 609. locking block; 6010. distance sensor; 6011. baffle; 6012. lifting spring; 6013. blocking column; 6014. positioning column. DETAILED DESCRIPTION

[0038] Embodiment 1

[0039] Please refer to Figure 1 as well as Figure 7 As shown, the present invention is a small animal drug injection device, comprising:

[0040] A base 1, a medicine storage box 2 and a protective sleeve 3 are fixedly connected to the top of the base 1;

[0041] The protection mechanism includes a sealing plate 203 fixedly connected to the inner wall of the medicine storage box 2, and a movable plate 204 rotatably connected to the inner wall of the medicine storage box 2. The tops of the sealing plate 203 and the movable plate 204 are both provided with a plurality of through holes distributed in a circular array;

[0042] The bearing mechanism includes a servo motor 405 movably arranged on the top of the base 1, a mounting plate 406 sleeved on the outer side wall of the output end of the servo motor 405, and a bearing plate 407 fixedly connected to the output end of the servo motor 405 for placing the syringe;

[0043] The syringe comprises a syringe 501 penetrating the carrier plate 407, a piston 502 movably disposed inside the syringe 501, and a push-pull handle 503 fixedly connected to the top of the piston 502;

[0044] The injection mechanism includes an electric push rod 601 fixedly connected to the bottom of the mounting plate 406 , a fixing sleeve 602 fixedly connected to the output end of the electric push rod 601 , and a connecting piece movably arranged inside the fixing sleeve 602 for driving the push-pull handle 503 .

[0045] The bearing mechanism also includes a driving motor 401 fixedly connected to the inner side wall of the protective sleeve 3, a transmission plate 402 fixedly connected to the output end of the driving motor 401, a hydraulic cylinder 403 fixedly connected to the top of the transmission plate 402, and a horizontal plate 404 fixedly connected to the output end of the hydraulic cylinder 403;

[0046] The top of the servo motor 405 is fixedly connected to the bottom of the horizontal plate 404, and the mounting plate 406 is fixedly connected to the horizontal plate 404 via a connecting rod. The driving motor 401 can drive the transmission plate 402 and the horizontal plate 404 to rotate, and the hydraulic cylinder 403 can drive the horizontal plate 404 to rise and fall, thereby adjusting the position of the carrier plate 407 and the syringe.

[0047] A plurality of through holes are provided at the bottom of the carrier plate 407, the inner diameter of the through holes is equal to the outer diameter of the syringe 501, and the number of the through holes is one more than the number of syringes. The syringes are plugged into the through holes in sequence, and then the servo motor 405 is started to make the syringe 501 correspond one-to-one with the fixed sleeve 602.

[0048] The connecting part also includes a positioning column 6014 fixedly connected to the top of the supporting plate 407, and a positioning hole opened at the top of the syringe 501. The outer diameter of the positioning column 6014 is equal to the inner diameter of the positioning hole. Through the cooperation between the positioning column 6014 and the positioning hole, the syringe 501 is fixed in a constant position and the storage groove is ensured to be directly opposite to the locking groove.

[0049] First, insert the syringe into the through hole and make the positioning column 6014 pass through the positioning hole, then start the servo motor 405 to drive the carrier plate 407 to rotate, so as to expose the next through hole, and then repeat the above operation to insert the syringe into the through hole in turn. When the insertion is completed, one of the through holes is idle, and the other through holes correspond to the fixing sleeve 602 one by one.

[0050] Embodiment 2

[0051] Please refer to Figure 1 - Figure 8 As shown, the present invention is a small animal drug injection device, comprising:

[0052] A base 1, a medicine storage box 2 and a protective sleeve 3 are fixedly connected to the top of the base 1;

[0053] The protection mechanism includes a sealing plate 203 fixedly connected to the inner wall of the medicine storage box 2, and a movable plate 204 rotatably connected to the inner wall of the medicine storage box 2. The tops of the sealing plate 203 and the movable plate 204 are both provided with a plurality of through holes distributed in a circular array;

[0054] The bearing mechanism includes a servo motor 405 movably arranged on the top of the base 1, a mounting plate 406 sleeved on the outer side wall of the output end of the servo motor 405, and a bearing plate 407 fixedly connected to the output end of the servo motor 405 for placing the syringe;

[0055] The syringe comprises a syringe 501 penetrating the carrier plate 407, a piston 502 movably disposed inside the syringe 501, and a push-pull handle 503 fixedly connected to the top of the piston 502;

[0056] The injection mechanism includes an electric push rod 601 fixedly connected to the bottom of the mounting plate 406 , a fixing sleeve 602 fixedly connected to the output end of the electric push rod 601 , and a connecting piece movably arranged inside the fixing sleeve 602 for driving the push-pull handle 503 .

[0057] The injection mechanism also includes a micro motor 603 fixedly connected to the inner top wall of the fixed sleeve 602, a screw rod 604 fixedly connected to the output end of the micro motor 603, and a movable seat 605 threadedly connected to the outer side wall of the screw rod 604;

[0058] The connecting piece is fixedly connected to the bottom of the movable seat 605, and the micro motor 603 can drive the lead screw 604 to rotate, thereby driving the movable seat 605 and the connecting piece to perform linear motion.

[0059] The connecting part includes a movable sleeve 606 fixedly connected to the bottom of the movable seat 605, an electromagnet 607 embedded in the movable sleeve 606, a storage groove opened on the outer wall of the movable sleeve 606, a connecting spring 608 fixedly connected to the inner wall of the storage groove, and a locking block 609 fixedly connected to the end face of the connecting spring 608. A groove is opened at the top center of the push-pull handle 503, and a locking groove is opened on the inner wall of the groove. The locking block 609 is made of ferromagnetic material. By inserting the movable sleeve 606 into the groove and making the locking groove face the storage groove, and then cutting off the power of the electromagnet 607, the locking block 609 will be inserted into the locking groove under the action of the connecting spring 608, so that the movable sleeve 606 is connected to the push-pull handle 503.

[0060] The connecting piece also includes a distance measuring sensor 6010 embedded in the locking block 609 near the end face of the connecting spring 608, a slide groove opened at the bottom of the locking groove, and a baffle 6011 movably arranged inside the slide groove, wherein the baffle 6011 can be completely retracted into the interior of the slide groove.

[0061] The connecting part also includes a spring groove opened on the inner wall of the locking groove, a lifting spring 6012 fixedly connected to the inner wall of the spring groove, and a blocking column 6013 fixedly connected to the top of the lifting spring 6012. The baffle 6011 and the blocking column 6013 are both permanent magnets, and the blocking column 6013 can absorb the baffle 6011 to fix it in the locking groove.

[0062] The connecting part also includes a positioning column 6014 fixedly connected to the top of the supporting plate 407, and a positioning hole opened at the top of the syringe 501. The outer diameter of the positioning column 6014 is equal to the inner diameter of the positioning hole. Through the cooperation between the positioning column 6014 and the positioning hole, the syringe 501 is fixed in a constant position and the storage groove is ensured to be directly opposite to the locking groove.

[0063] A stirring motor 201 is fixedly connected to the inside of the medicine storage box 2, and a stirring fan blade 202 is fixedly connected to the outer wall of the output end of the stirring motor 201. By delivering the medicine into the medicine storage box 2 and driving the stirring fan blade 202 to rotate by the stirring motor 201, the medicine can be prevented from being stratified due to standing still.

[0064] The outer wall of the transmission plate 402 is fixedly connected with a main gear 206, and the outer wall of the movable plate 204 is fixedly connected with a driven gear 205. The main gear 206 is meshed with the driven gear 205. When the driving motor 401 drives the transmission plate 402 to rotate, the movable plate 204 is driven to rotate through the action of the two gears, thereby adjusting the position of the movable plate 204, and then the through holes on the movable plate 204 are staggered with the through holes on the sealing plate 203, so as to seal the medicine storage box 2.

[0065] When the syringe is inserted, the electric push rod 601 is started to drive the fixed sleeve 602 to move downward until the syringe 501 is fixed under the action of the fixed sleeve 602 and the carrier plate 407. At this time, the syringe is located directly above the medicine storage box 2, and the through holes of the sealing plate 203 and the movable plate 204 are overlapped. Then the hydraulic cylinder 403 is started, and the syringe is inserted into the interior of the medicine storage box 2. The syringe 501 will be inserted below the liquid surface. Then the micro motor 603 is started to rotate forward, thereby driving the screw rod 604 to rotate, so as to achieve the downward movement of the movable seat 605 and the movable sleeve 606 until the movable sleeve 606 is inserted into the groove. At this time, the locking groove is opposite to the storage groove. Then the electromagnet 607 is powered off. At this time, the locking block 609 will be inserted into the locking groove under the action of the connecting spring 608, so that the movable sleeve 606 is connected to the push-pull handle 503.

[0066] By starting the micro motor 603 to reverse, the movable sleeve 606 and the push-pull handle 503 are driven to move upward, and then the liquid medicine is drawn into the inside of the syringe 501. The servo motor 405 and the screw rod 604 are set to accurately control the rising distance of the push-pull handle 503, so as to achieve accurate medicine extraction;

[0067] When the medicine is taken, the syringe is moved out of the medicine storage box 2 by the hydraulic cylinder 403, and then the driving motor 401 is started, so that the transmission plate 402 and the syringe rotate, thereby moving the syringe to the other side of the medicine storage box 2. During this process, the transmission plate 402 will drive the main gear 206 to rotate, and then drive the driven gear 205 meshing therewith to rotate, so as to adjust the position of the movable plate 204, and make the through holes on the movable plate 204 intersect with the through holes on the sealing plate 203, so as to achieve the sealing effect of the medicine storage box 2. After that, a mouse is taken out, and the injection needle is installed on the syringe, so that the syringe is plugged into the mouse, and the micro motor 603 is started, so as to drive the connecting piece and the push-pull handle 503 to move downward, so as to inject a certain amount of liquid medicine into the body of the mouse;

[0068] When the injection is completed, the electromagnet 607 is energized to give it magnetic force, thereby adsorbing the locking block 609 and compressing the connecting spring 608 until the locking block 609 is completely retracted into the storage groove. At this time, the blocking column 6013 will move to the locking groove under the action of the lifting spring 6012, thereby blocking the locking groove and preventing the reuse of the syringe. The distance measuring sensor 6010 provided therein is used to detect the moving position of the locking block 609 to ensure that the locking block 609 can be fully inserted into the locking groove.

Claims

1. A drug injection device for small animals, characterized in that: include: A base (1), the top of which is fixedly connected with a medicine storage box (2) and a protective sleeve (3); A protection mechanism, the protection mechanism comprising a sealing plate (203) fixedly connected to the inner wall of the medicine storage box (2), and a movable plate (204) rotatably connected to the inner wall of the medicine storage box (2), wherein the tops of the sealing plate (203) and the movable plate (204) are both provided with a plurality of through holes distributed in a circular array; A bearing mechanism, the bearing mechanism comprising a servo motor (405) movably arranged on the top of the base (1), a mounting plate (406) sleeved on the outer side wall of the output end of the servo motor (405), and a bearing plate (407) fixedly connected to the output end of the servo motor (405) for placing a syringe; A syringe, the syringe comprising a syringe barrel (501) penetrating a carrier plate (407), a piston (502) movably disposed inside the syringe barrel (501), and a push-pull handle (503) fixedly connected to the top of the piston (502); The injection mechanism comprises an electric push rod (601) fixedly connected to the bottom of the mounting plate (406), a fixing sleeve (602) fixedly connected to the output end of the electric push rod (601), and a connecting piece movably arranged inside the fixing sleeve (602) for driving the push-pull handle (503).

2. A small animal drug injection device according to claim 1, characterized in that: The bearing mechanism further comprises a driving motor (401) fixedly connected to the inner side wall of the protective sleeve (3), a transmission plate (402) fixedly connected to the output end of the driving motor (401), a hydraulic cylinder (403) fixedly connected to the top of the transmission plate (402), and a horizontal plate (404) fixedly connected to the output end of the hydraulic cylinder (403); The top of the servo motor (405) is fixedly connected to the bottom of the horizontal plate (404), and the mounting plate (406) is fixedly connected to the horizontal plate (404) via a connecting rod.

3. A small animal drug injection device according to claim 1, characterized in that: A plurality of through holes are provided at the bottom of the carrier plate (407), the inner diameter of the through holes being equal to the outer diameter of the syringe (501), and the number of the through holes is one more than the number of syringes.

4. A small animal drug injection device according to claim 1, characterized in that: The injection mechanism further comprises a micro motor (603) fixedly connected to the inner top wall of the fixed sleeve (602), a screw rod (604) fixedly connected to the output end of the micro motor (603), and a movable seat (605) threadedly connected to the outer side wall of the screw rod (604); The connecting piece is fixedly connected to the bottom of the movable seat (605).

5. A small animal drug injection device according to claim 4, characterized in that: The connecting member includes a movable sleeve (606) fixedly connected to the bottom of the movable seat (605), an electromagnet (607) embedded in the movable sleeve (606), a storage groove opened on the outer wall of the movable sleeve (606), a connecting spring (608) fixedly connected to the inner wall of the storage groove, and a locking block (609) fixedly connected to the end face of the connecting spring (608), and a groove is opened at the top center of the push-pull handle (503), and a locking groove is opened on the inner wall of the groove.

6. A small animal drug injection device according to claim 5, characterized in that: The connecting member also includes a distance measuring sensor (6010) embedded in the locking block (609) near the end surface of the connecting spring (608), a slide groove opened at the bottom of the locking groove, and a baffle (6011) movably arranged inside the slide groove.

7. A small animal drug injection device according to claim 6, characterized in that: The connecting member also includes a spring groove opened on the inner side wall of the locking groove, a lifting spring (6012) fixedly connected to the inner side wall of the spring groove, and a blocking column (6013) fixedly connected to the top of the lifting spring (6012), and the baffle (6011) and the blocking column (6013) are both permanent magnets.

8. A small animal drug injection device according to claim 7, characterized in that: The connecting member also includes a positioning column (6014) fixedly connected to the top of the carrier plate (407), and a positioning hole opened at the top of the syringe (501), and the outer diameter of the positioning column (6014) is equal to the inner diameter of the positioning hole.

9. A small animal drug injection device according to claim 1, characterized in that: The medicine storage box (2) is fixedly connected to a stirring motor (201) inside, and a stirring fan blade (202) is fixedly connected to the outer side wall of the output end of the stirring motor (201).

10. A small animal drug injection device according to claim 2, characterized in that: The outer wall of the transmission plate (402) is fixedly connected to a main gear (206), and the outer wall of the movable plate (204) is fixedly connected to a driven gear (205), and the main gear (206) is meshed with the driven gear (205).

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