Artificial prostheses and applications

Abstract

The application discloses an artificial prosthesis and application, which is prepared by using an artificial prosthesis material, and has a villus layer formed by villi on the surface of the artificial prosthesis; a suture is arranged on the surface of the artificial prosthesis, and the suture is arranged in the villus layer and is bound and connected to the surface of the artificial prosthesis through the villus layer. The application can be well applied to the arrangement of a marking line on the surface of a prosthesis such as a patch, a valve and a blood vessel, and can be used for the connection between a ring formed by a suture and a blood vessel prosthesis when the blood vessel prosthesis is prepared in a bellows structure, so that it is possible to prepare the blood vessel prosthesis in the bellows structure by using a biological material.

Description

Technical Field

[0001] This invention belongs to the field of biomedical technology, specifically relating to an artificial prosthesis and its application. Background Technology

[0002] Currently, prostheses such as patches, valves, and blood vessels are widely used in clinical treatment. Prosthetic materials are usually made of polymer fabrics, biomaterials, etc. During the prosthesis molding process, it is usually necessary to avoid damaging the materials themselves as much as possible while ensuring the shape and function of the prosthesis, so as to ensure that the prosthesis has good performance. Summary of the Invention

[0003] The purpose of this invention is to provide an artificial prosthesis that reduces damage to the artificial prosthesis material during the fabrication and molding process, and facilitates the fabrication of the artificial prosthesis.

[0004] This invention is achieved through the following technical solution:

[0005] An artificial prosthesis is made from artificial prosthesis material. The surface of the artificial prosthesis has a pile layer formed by fibers. Sutures are provided on the surface of the artificial prosthesis. The sutures are inserted into the pile layer and are bound to the surface of the artificial prosthesis by the pile layer.

[0006] In some embodiments of the present invention, the fibers are connected to the artificial prosthesis material at one end and the free ends of the fibers are interwoven with each other, or the fibers are connected to the artificial prosthesis material at both ends, forming a fiber layer that can bind the suture to the artificial prosthesis when the suture is passed through the fiber layer.

[0007] In some embodiments of the present invention, the artificial prosthesis material is a biomaterial with a villous layer on its surface.

[0008] In some embodiments of the present invention, the biomaterial is bovine pericardium material.

[0009] In some embodiments of the present invention, the artificial prosthesis material is a non-biological material, and the non-biological material has a textured surface with the aforementioned fluff layer.

[0010] On the other hand, the present invention also provides an application of the artificial prosthesis as a patch, valve, or vascular prosthesis.

[0011] In some embodiments of the present invention, the suture forms a marking line on the surface of the artificial prosthesis.

[0012] In some embodiments of the present invention, the artificial prosthesis is tubular, and the sutures are wound around the artificial prosthesis and form multiple closed loops on the artificial prosthesis. The loops bind the artificial prosthesis at corresponding positions, so that the artificial prosthesis has a corrugated tubular structure with troughs at the locations of the loops and crests between the loops.

[0013] Compared with the prior art, the present invention has the following advantages and beneficial effects:

[0014] By utilizing the inherent fibers on the surface of the prosthesis material itself or by creating fibers on the surface of the prosthesis material, a fiber layer is formed on the surface of the prosthesis material. This fiber layer serves as the base for the connection between the sutures and other structures set in the artificial prosthesis fabrication process and the artificial prosthesis. When it is necessary to connect sutures such as marking lines to the artificial prosthesis, the sutures can be stably connected to the artificial prosthesis without penetrating the prosthesis material. This avoids the problem of leakage at the suture penetration point on the artificial prosthesis caused by the need for sutures to penetrate the artificial prosthesis material during connection, thus ensuring the performance of the prepared artificial prosthesis material and facilitating the fabrication of artificial prostheses.

[0015] This invention can be well applied to setting marking lines on the surface of prostheses such as patches, valves, and blood vessels, and can be used to connect the ring formed by sutures to the blood vessel prosthesis when preparing a corrugated structure, making it possible to prepare corrugated structure blood vessel prostheses using biomaterials. Attached Figure Description

[0016] To more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings in the embodiments will be briefly described below. It should be understood that the following drawings only show some embodiments of the present invention and should not be regarded as a limitation on the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the connection structure between the sutures and the pile layer on the surface of the sheet-like artificial prosthesis in an embodiment of the present invention.

[0018] Figure 2 This is a schematic diagram of the connection structure between the sutures and the pile layer on the surface of the tubular artificial prosthesis in an embodiment of the present invention.

[0019] Figure 3 This is a schematic diagram illustrating the application of the method of connecting sutures using a villous layer in the fabrication of a corrugated tubular vascular prosthesis, as described in this embodiment of the invention.

[0020] in:

[0021] 10. Artificial prosthesis; 11. Villus layer;

[0022] 21. Marking line; 22. Ring. Detailed Implementation

[0023] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are some embodiments of the present invention, but not all embodiments.

[0024] In the application of artificial prosthesis materials, taking the setting of marking lines on the prepared artificial prosthesis as an example, in order to stably connect the marking lines to the surface of the artificial prosthesis, it is usually necessary to connect the sutures used to form the marking lines to the artificial prosthesis by sewing. The artificial prosthesis obtained by this preparation method has the risk of leakage at the pinhole positions formed by the suture sewing, which affects the performance of the artificial prosthesis.

[0025] In other applications of artificial prosthesis fabrication, such as when using biomaterials to fabricate corrugated vascular prostheses, refer to... Figure 3 One molding method involves wrapping sutures around a pre-formed tube, forming multiple closed loops on the tube. These loops then bind the tube at corresponding positions, creating troughs on the tube and peaks between the loops, resulting in a corrugated vascular prosthesis.

[0026] To achieve the molding of this corrugated tubular vascular prosthesis using the above molding method, an important prerequisite is that the suture-formed loop can be stably connected to the tube body. Therefore, there is also a need to know how to fix the suture to the artificial prosthesis.

[0027] Based on the actual needs and problems in the preparation of artificial prostheses, when using biological materials such as bovine pericardium to prepare artificial prostheses, it was found that one side of the surface of the bovine pericardium material has a villous layer formed by villi. The structural characteristics of these villi are that some villi are connected to the bovine pericardium at one end and intertwined at the other end, while some villi are connected to the bovine pericardium material at both ends. At this time, there are a large number of closed pores inside the villous layer on the surface of the bovine pericardium material. By utilizing the closed pores in the villous layer, when sutures are inserted into the villous layer, the sutures can be stably bound and connected to the surface of the artificial prosthesis.

[0028] Based on the aforementioned structural characteristics of biomaterials, the inventors applied them to the preparation of artificial prostheses, effectively solving the problems of poor connection and leakage at the connection point when setting sutures on the surface of artificial prostheses.

[0029] In some embodiments of the present invention, reference is made to Figure 1The artificial prosthesis 10 is made of artificial prosthesis material and the surface of the artificial prosthesis has a pile layer 11 formed by pile. The artificial prosthesis 10 has sutures on its surface, which are inserted into the pile layer 11 and are bound to the artificial prosthesis surface through the pile layer.

[0030] In some embodiments, the fibers are connected to the artificial prosthesis material at one end and the free ends of the fibers are interwoven, or the fibers are connected to the artificial prosthesis material at both ends, forming a fiber layer that can bind the suture to the artificial prosthesis when the suture is passed through the fiber layer, such that the formed fiber layer has a large number of closed pores inside.

[0031] In some embodiments, the prosthetic material can be directly made from biomaterials with a villous layer on the surface, such as thin sheets of tissue like the pericardium of a human or animal, for example, bovine pericardium. When using such biomaterials to prepare prostheses, the villous layer on the surface enables stable connection of sutures to the surface of the prosthesis.

[0032] Artificial prosthesis materials can also be made of non-biological materials, such as membranes made of polymer materials. The surface of such membranes is usually smooth, and it is difficult to fix sutures on such surfaces without damaging the membrane material. Based on the technical concept in this invention, a fluff layer with the above-mentioned structural characteristics can be formed on the surface of non-biological materials, and then the fluff layer can be used to connect sutures, which effectively solves the problems existing when using non-biological materials to prepare artificial prostheses.

[0033] The artificial prostheses mentioned here can be patches, valves, vascular prostheses, etc., but are not limited to the prosthetic products listed above.

[0034] On the other hand, some embodiments of the present invention also involve the application of the above-mentioned artificial prosthesis as a patch, valve, or vascular prosthesis.

[0035] In the above applications, the sutures placed on the surface of the artificial prosthesis form marking lines 21 on the surface of the artificial prosthesis. For example, in the preparation of a patch, referring to... Figure 1 Taking setting a marking line on the surface of the patch as an example, at this time, it is only necessary to insert the sewing thread into the pile layer to form the required marking line 21 on the surface of the patch, and the marking line can be stably connected to the surface of the patch.

[0036] Taking its application in vascular prostheses as an example, when using biomaterials to prepare vascular prostheses with a corrugated tubular structure, refer to... Figure 2 and Figure 3One molding method involves rolling and sewing sheet-like biomaterials into a tube, then wrapping sutures around the tube to form multiple spaced closed rings 22. These rings bind the artificial prosthesis at corresponding positions. When the artificial prosthesis is in an inflated state, troughs are formed at the locations of the rings, and crests are formed between the rings, thus obtaining a corrugated tubular vascular prosthesis.

[0037] Of course, refer to Figure 3 Marking lines 21 can also be set on the surface of the vascular prosthesis along its axial direction. The marking lines 21 pass through the villous layer on the surface of the vascular prosthesis and are connected to the vascular prosthesis.

[0038] Taking a tube made of pericarp material as an example, the pericarp material typically has one smooth side and one side with a nap. During molding, the smooth side of the pericarp forms the inner wall of the tube, while the outer wall of the tube is covered with a nap layer 11 formed by the nap. This nap layer 11 is similar to the adhesive surface of Velcro, with internal pores that allow stitches to pass through. When the stitches are threaded through the nap layer, the structural characteristics of the nap layer allow the loops formed by the stitches to be stably connected to the outer wall of the tube.

[0039] In the preparation of the above-mentioned vascular prosthesis, the ring is connected to the tube body through the villous layer on the outer wall of the tube body. This not only facilitates the connection of the restraining ring on the outer wall of the tube body, but also ensures that the connection of the restraining ring on the tube body will not cause any damage to the bovine pericardial material. This has great practical application value and significance in the preparation and application of artificial prostheses.

[0040] In the description of this invention, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., used to indicate the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship that the product of this invention is usually placed in during use. They are only for the convenience of describing this invention and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0041] Furthermore, the use of terms such as "horizontal" and "vertical" in the description of this invention does not imply that the components are required to be absolutely horizontal or suspended, but rather that they can be slightly tilted. For example, "horizontal" simply means that its direction is more horizontal than "vertical," and does not mean that the structure must be completely horizontal, but can be slightly tilted.

[0042] In the description of this invention, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this invention in light of the specific circumstances.

[0043] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Any simple modifications or equivalent changes made to the above embodiments based on the technical essence of the present invention shall fall within the protection scope of the present invention.

Claims

1. Artificial prosthesis, characterized in that, The artificial prosthesis is formed by using artificial prosthesis material, and a velvet layer is formed on the surface of the artificial prosthesis by using velvet. Sutures are arranged on the surface of the artificial prosthesis, and the sutures are arranged in the velvet layer and are bound to the surface of the artificial prosthesis through the velvet layer. The velvet is connected to the artificial prosthesis material at one end and the free ends of the velvet are intertwined with each other, or the velvet is connected to the artificial prosthesis material at both ends, so that the velvet layer formed has pores for the sutures to pass through, and the velvet layer formed can bind the sutures to the artificial prosthesis when the sutures are arranged in the velvet layer.

2. The artificial prosthesis of claim 1, wherein, The artificial prosthesis material is a biological material having a velvet layer on the surface.

3. The artificial prosthesis of claim 2, wherein, The biological material is bovine pericardium material.

4. The artificial prosthesis of claim 1, wherein, The artificial prosthesis material is a non-biological material, and the non-biological material is formed with the velvet layer on the surface.

5. Use of the artificial prosthesis according to any one of claims 1-4 in manufacturing a patch, a valve or a vascular prosthesis.

6. Use according to claim 5, characterized in that, The sutures form a mark line on the surface of the artificial prosthesis.

7. Use according to claim 5, characterized in that, The artificial prosthesis is in a tubular shape, the sutures are arranged on the artificial prosthesis and form a plurality of closed loops on the artificial prosthesis, and the artificial prosthesis is in a bellows shape having wave troughs at positions where the loops are located and wave crests between the loops by binding the artificial prosthesis at corresponding positions by the loops.

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