Sophora flavescens sitting bath lotion and preparation method thereof

Abstract

The invention relates to the technical field of traditional Chinese medicine compositions, and particularly discloses radix sophorae flavescentis sitting bath liquid and a preparation method thereof.The radix sophorae flavescentis sitting bath liquid is prepared from, by weight, 15-25 g of rhizoma coptidis, 15-25 g of cortex phellodendri, 15-25 g of radix et rhizoma rhei, 15-25 g of flos carthami, 1-2 g of borneol, 25-35 g of radix sanguisorbae, 25-35 g of radix sophorae flavescentis, 15-25 g of fructus kochiae, 15-25 g of fructus cnidii, 15-25 g of rhizoma polygoni cuspidati, 15-25 g of radix angelicae, 15-25 g of sappan wood, 15-25 g of rhizoma bletillae and 2-4 g of catechu. The preparation method comprises the following steps: taking the medicines according to the weight ratio, cleaning, drying, putting into a medicine bag, infiltrating with water for 15-25 minutes in a traditional Chinese medicine decocting machine, extracting for 35-45 minutes under micro pressure, sub-packaging into packaging bags, sterilizing for 25-35 minutes at the high temperature of 100 DEG C, and storing in a dark place at the low temperature of 20 DEG C or below. The traditional Chinese medicine has the beneficial effects that the effects of clearing away heat and toxic materials and relieving swelling and pain can be achieved through the pharmacological action and comprehensive action of the traditional Chinese medicinal materials; the traditional Chinese medicine is suitable for treating patients with symptoms such as anal fistula, perianal abscess, hemorrhoids, wound edema, hyperemia and pain after fistula operation, and the treatment effect is remarkable.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a kushen sitz bath liquid and a preparation method thereof. Background Art

[0002] The prior art lacks a Chinese patent medicine that directly acts on anal lesions and is suitable for treating patients with symptoms such as anal fistula, perianal abscess, hemorrhoids, and postoperative wound edema, congestion, pain, etc. Therefore, a Sophora flavescens sitz bath liquid and a preparation method thereof are proposed. Summary of the invention

[0003] In order to effectively solve the problems in the background technology and overcome the technical defects in the prior art, the present invention provides the following technical solutions: The Sophora flavescens sitz bath liquid is prepared from the following raw material medicinal components in weight ratio: 15-25g of Coptis chinensis, 15-25g of Phellodendron chinense, 15-25g of Rhubarb, 15-25g of Carthamus tinctorius, 1-2g of Borneolum Syntheticum, 25-35g of Sanguisorba officinalis, 25-35g of Sophora flavescens, 15-25g of Kochia scoparia, 15-25g of Cnidium monnieri, 15-25g of Polygonum cuspidatum, 15-25g of Angelica dahurica, 15-25g of Sappan wood, 15-25g of Bletilla striata, and 2-4g of catechu.

[0004] As a preferred technical solution of the present invention, it is made of the following raw material drug components in weight ratio: 15g of Coptidis Rhizoma, 15g of Phellodendron Amurense, 15g of Rhubarb, 15g of Carthamus tinctorius, 1g of Borneolum Syntheticum, 25g of Sanguisorba officinalis, 25g of Sophora flavescens, 15g of Kochia scoparia, 15g of Cnidium monnieri, 15g of Polygonum cuspidatum, 15g of Angelica dahurica, 15-25g of Sappanwood, 15g of Bletilla striata, and 2g of catechu.

[0005] As a preferred technical solution of the present invention, it is made of the following raw material drug components in weight ratio: 20g of Coptidis Rhizoma, 20g of Phellodendron Amurense, 20g of Rhubarb, 20g of Carthamus tinctorius, 1.5g of Borneolum Syntheticum, 30g of Sanguisorba Officinalis, 30g of Sophora Flavescentis, 20g of Kochia scoparia, 20g of Cnidium monnieri, 20g of Polygonum cuspidatum, 20g of Angelica dahurica, 20g of Sappanwood, 20g of Bletilla striata, and 3g of catechu.

[0006] As a preferred technical solution of the present invention, it is made of the following raw material drug components in weight ratio: 25g of Coptis chinensis, 25g of Phellodendron chinense, 25g of Rhubarb, 25g of Carthamus tinctorius, 2g of Borneolum, 35g of Sanguisorba officinalis, 35g of Sophora flavescens, 25g of Kochia scoparia, 25g of Cnidium monnieri, 25g of Polygonum cuspidatum, 25g of Angelica dahurica, 25g of Sappan wood, 25g of Bletilla striata, and 4g of catechu.

[0007] The preparation method of Sophora flavescens sitz bath liquid comprises the following steps: Step 1: Take the above medicinal materials in corresponding proportions according to the weight ratio, wash and set aside; Step 2: Use drying equipment to dry the washed medicinal materials in step 1, and put them into medicine bags for decoction for later use; Step 3: Place the medicine bag filled with medicinal materials in step 2 into a Chinese medicine decoction machine, add an appropriate amount of water to soak for 15-25 minutes, and extract under slight pressure for 35-45 minutes; Step 4: Pack the medicinal liquid extracted in step 3 into packaging bags and sterilize them at 100° C. for 25-35 minutes to complete the preparation of the Sophora flavescens sitz bath solution.

[0008] As a preferred technical solution of the present invention, the capacity of the packaging bag in step three is 250 ml.

[0009] As a preferred technical solution of the present invention, the drug solution prepared in step 4 and packaged in the packaging bag is stored in a low temperature environment below 20° C. and away from light.

[0010] Compared with the prior art, the beneficial effects of the present invention are: through the pharmacological effects and comprehensive effects of various Chinese medicinal materials, the effects of clearing away heat and detoxifying, reducing swelling and relieving pain can be achieved; it is suitable for treating patients with symptoms such as anal fistula, perianal abscess, hemorrhoids, and postoperative wound edema, congestion, pain, etc., and the therapeutic effect is significant.

[0011] The medicinal properties and effects of each drug in the present invention are as follows: Coptis chinensis: bitter in taste, cold in nature; enters the heart, liver, stomach, and large intestine meridians; has the effects of clearing away heat and dampness, purging fire and detoxifying; can be used to treat diarrhea, dysentery, vomiting and acid reflux caused by damp-heat in the stomach and intestines; can also treat symptoms such as restlessness and thirst, high fever and irritability, coma and delirium caused by fever; can also treat hyperactivity of heart fire, insufficient yin and blood, irritability and insomnia, vomiting blood, nosebleeds, and fire poison sores.

[0012] Huangbai: bitter in taste, cold in nature, enters the kidney meridian, bladder meridian, and large intestine meridian. Functions and indications: clearing away heat and detoxifying, purging fire and drying dampness. It is mainly used to treat acute bacterial dysentery, acute enteritis, acute icteric hepatitis, urinary tract infection and other inflammations. It can be used externally to treat burns, otitis media, acute conjunctivitis, etc.

[0013] Rhubarb: bitter in taste, cold in nature; enters the spleen, stomach, large intestine, liver, and heart meridians; Efficacy: has the effects of purging and attacking accumulation, clearing away heat and purging fire, cooling blood and detoxifying, removing blood stasis and dredging menstruation, and promoting dampness and jaundice; Indications: used for constipation due to excess heat accumulation, vomiting and bleeding due to blood heat, red eyes and swollen throat, carbuncle treatment, abdominal pain due to intestinal carbuncle, amenorrhea due to blood stasis, postpartum blood stasis, traumatic injuries, damp-heat dysentery, jaundice and red urine, stranguria, edema; external treatment of burns and scalds.

[0014] Safflower: pungent, warm; enters the heart and liver meridians; Functions and indications: promotes blood circulation and regulates menstruation, dissipates blood stasis and relieves pain, used for amenorrhea, dysmenorrhea, lochia retention, abdominal masses, injuries from falls, and sores and swelling.

[0015] Borneol: It tastes pungent and bitter, is slightly cold in nature, and enters the heart, spleen, and lung meridians. Its functions and indications: It can open all orifices, disperse stagnant fire, remove cataracts and improve eyesight, reduce swelling and relieve pain; it can treat lockjaw caused by stroke, coma caused by fever, epilepsy, phlegm, qi stagnation, deafness, throat paralysis, mouth ulcers, otitis media, carbuncle, hemorrhoids, conjunctivitis and cataracts, and pinworm disease.

[0016] Radix Sanguisorbae: bitter and sour, non-toxic, cold in nature; enters the liver, lung, kidney, and large intestine meridians. Functions and indications: has the functions of cooling blood and stopping bleeding, clearing away heat and detoxifying, promoting tissue regeneration and healing sores; treats bloody stools, bloody dysentery, hemorrhoidal bleeding, hematuria, metrorrhagia, carbuncles, sores, burns, and scalds.

[0017] Sophora flavescens: bitter in taste, cold in nature; enters the heart, liver, stomach, large intestine, and bladder meridians; functions and indications: clearing away heat and dampness, killing parasites, and promoting diuresis; used for heat dysentery, bloody stool, jaundice and urine retention, leucorrhea, vaginal swelling and itching, eczema, wet sores, skin itching, scabies and leprosy; external treatment of trichomoniasis vaginitis.

[0018] Kochia scoparia seeds: pungent and bitter in taste, cold in nature; enters the kidney and bladder meridians; functions and indications: clears heat and dampness, dispels wind and relieves itching; used for painful urination, vaginal itching and leucorrhea, rashes, eczema, and skin itching.

[0019] Cnidium monnieri: pungent and bitter in taste; warm in nature; enters the spleen and kidney meridians; functions and indications: warms the kidney and strengthens yang, dries dampness and kills insects, dispels wind and relieves itching; used for male impotence, scrotal dampness and itching, female uterine cold and infertility, cold and damp leucorrhea, vaginal itching and swelling, rheumatic arthralgia, wet sores and scabies.

[0020] Polygonum cuspidatum: slightly bitter, slightly cold; enters the liver, gallbladder, and lung meridians; functions to clear away heat and detoxify, promote bile secretion and reduce jaundice, dispel wind and dampness, disperse blood stasis and relieve pain, relieve cough and resolve phlegm; used for joint pain, damp-heat jaundice, amenorrhea, leukorrhea, cough with excessive sputum, burns from water or fire, injuries from falls, carbuncles, swellings, and sores.

[0021] Angelica dahurica: spicy, warm in nature; enters the lung, spleen, and stomach meridians; functions and indications: dispels exterior cold, dispels wind and relieves pain, unclogs the nasal passages, dries up dampness and stops leukorrhea, reduces swelling and discharges pus, dispels wind and relieves itching; used for wind-cold colds, headaches, toothaches, rheumatic pain, sinusitis, leukorrhea, sores, carbuncles, and swelling.

[0022] Su Mu: sweet, salty, and neutral in taste; enters the heart, liver, and spleen meridians; functions and indications: promotes blood circulation, removes blood stasis, reduces swelling and relieves pain; used for amenorrhea, dysmenorrhea, postpartum blood stasis, stabbing pain in the chest and abdomen, and swelling and pain caused by trauma.

[0023] Bletilla striata: sweet, astringent, slightly cold; enters the lung, liver, and stomach meridians; functions and indications: astringent and hemostatic, swelling-reducing and tissue-generating; used for coughing up blood and vomiting blood, bleeding from trauma, swelling and pus in sores, chapped skin; coughing up blood due to tuberculosis, and bleeding from ulcer disease.

[0024] Catechu: bitter, astringent, slightly cold; enters the lung meridian; functions and indications: absorbs dampness, promotes tissue regeneration, and heals sores. Used for ulcers that do not heal, eczema, mouth sores, pain from falls, and bleeding from trauma.

[0025] The division and function analysis of the monarch, minister, assistant and envoy ingredients in the formula of the present invention are as follows: King medicine: Coptis chinensis, Phellodendron chinense: Coptis chinensis can clear away heat and dampness, purge fire and detoxify, and is particularly effective for treating damp-heat and heat-toxic diseases in the middle jiao; Phellodendron chinense can clear away heat and dampness, purge fire and detoxify, and reduce fever and eliminate steam, and is good at clearing damp-heat in the lower jiao. The two can be used together as the main medicine, mainly targeting heat toxicity and damp-heat evil in the body. For example, for diseases such as damp-heat dysentery and heat-toxic sores, Coptis chinensis and Phellodendron chinense can effectively clear damp-heat and heat-toxicity and relieve symptoms. For example, when treating oral ulcers caused by heat-toxicity, Coptis chinensis and Phellodendron chinense can reduce the redness, swelling, heat and pain of the oral mucosa by clearing away heat, purge fire and detoxify.

[0026] rhubarb: Rhubarb has the function of purging and attacking accumulation, clearing away heat and purging fire, cooling blood and removing toxins, and removing blood stasis and promoting menstruation. It can not only remove pathogenic factors such as accumulated heat and blood stasis in the intestines, but also expel heat and toxins from the stool through its purgative effect. In this prescription, rhubarb plays an important leading therapeutic role in treating conditions such as internal heat and toxins and constipation, so it can also be regarded as part of the main medicine. For example, in the treatment of Yangming Fu Shi syndrome, which is manifested by high fever, constipation, abdominal distension and other symptoms, rhubarb can purge heat and promote bowel movements, remove the firewood from the bottom of the pot, and relieve the condition.

[0027] Minister medicine: Sophora flavescens, Kochia scoparia, Cnidium monnieri: Sophora flavescens clears heat and dampness, kills insects and acts as a diuretic; Kochia scoparia clears heat and dampness, dispels wind and relieves itching; Cnidium monnieri warms the kidney and strengthens yang, removes dampness, dispels wind and kills insects. These three herbs assist the main herbs in strengthening the effects of clearing heat and dampness, dispelling wind and relieving itching. When treating skin itching, eczema and other diseases, they can assist the main herbs in removing pathogenic factors such as dampness, heat and wind evil from the skin surface. For example, for patients with eczema, Sophora flavescens can clear heat and dampness, Kochia scoparia and Cnidium monnieri can dispel wind and relieve itching, alleviating symptoms such as skin itching, redness and swelling.

[0028] Safflower, Sumac: Safflower can invigorate blood circulation and relieve menstruation, dissipate blood stasis and relieve pain; Su Mu can invigorate blood circulation and heal injuries, dissipate blood stasis and relieve menstruation. They are mainly used to assist the main medicine in exerting the effect of invigorating blood circulation and removing blood stasis. When heat toxicity or damp-heat evil causes blood stasis and blockage, and symptoms such as local pain and ecchymosis appear, safflower and Su Mu can help dissipate blood stasis and improve blood circulation. For example, in the case of local blood stasis and swelling after trauma, safflower and Su Mu can promote the dissipation of blood stasis and relieve pain.

[0029] Adjuvant: Sanguisorba officinalis, Bletilla striata, Catechu: Sanguisorba officinalis cools blood and stops bleeding, removes toxins and heals sores; Bletilla striata astringes and stops bleeding, reduces swelling and promotes tissue regeneration; Catechu astringes and stops bleeding, promotes tissue regeneration and heals sores. They mainly play the role of stopping bleeding and heal sores in prescriptions. Because pathogenic factors such as heat toxins and damp heat may damage the skin and veins, causing bleeding and ulcers. Sanguisorba officinalis, Bletilla striata and Catechu can prevent bleeding and promote healing of sores. For example, when there is blood in the stool caused by heat toxins or bleeding from skin sores, these three herbs can help stop bleeding and promote wound healing.

[0030] Angelica dahurica: Angelica dahurica can relieve cold, dispel wind and relieve pain, clear the nasal passages, dry dampness and stop leukorrhea, and reduce swelling and discharge pus. In the formula of the present invention, Angelica dahurica can assist the main drug and the auxiliary drug to play the role of reducing swelling and discharge pus, dispelling wind and relieving pain. At the same time, Angelica dahurica can also lead the medicine upward, and can better play the role of medicine for symptoms such as heat toxic sores, swelling and pain on the head and face. For example, when treating sinusitis or head and face acne, Angelica dahurica can help other drugs to play a better therapeutic effect.

[0031] Borneol: Borneol can invigorate the mind, clear away heat and relieve pain. It can assist the main drug to enhance the effect of clearing heat and relieving pain, and can promote the drug to penetrate the skin and other tissues, enhancing the transdermal absorption of the drug. When treating skin heat, swelling and pain or oral ulcers, borneol can quickly relieve pain and make the drug work better.

[0032] Assistant drug: There is no typical assistant drug in the formula of the present invention, but from a broad perspective, the drugs in the formula are compatible with each other and work synergistically, and the drugs can also be considered to be assistant drugs. For example, the purgative effect of rhubarb can guide pathogens such as heat and toxins to be expelled from the body, and to some extent, it plays the role of "leading the meridians" and coordinating the overall action direction of the drugs. DETAILED DESCRIPTION

[0033] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution in the embodiment of the present invention will be further clearly and completely described below. Obviously, the described embodiment is only a part of the embodiment of the present invention, not all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] The invention provides a technical scheme: a sophora flavescens sitz bath liquid is prepared from the following raw material drug components in weight ratio: 15-25g of coptis root, 15-25g of phellodendron, 15-25g of rhubarb, 15-25g of safflower, 1-2g of borneol, 25-35g of sanguisorba officinalis, 25-35g of sophora flavescens, 15-25g of kochia scoparia, 15-25g of cnidium monnieri, 15-25g of polygonum cuspidatum, 15-25g of angelica dahurica, 15-25g of sappan wood, 15-25g of bletilla striata and 2-4g of catechu.

[0035] Embodiment 1: According to the weight ratio, take 15g of Coptis chinensis, 15g of Phellodendron chinense, 15g of Rhubarb, 15g of Carthamus tinctorius, 1g of Borneolum, 25g of Sanguisorba officinalis, 25g of Sophora flavescens, 15g of Kochia scoparia, 15g of Cnidium monnieri, 15g of Polygonum cuspidatum, 15g of Angelica dahurica, 15-25g of Sappan wood, 15g of Bletilla striata, and 2g of Catechu, wash and dry them, put them into medicine bags, soak them with water in a Chinese medicine decoction machine for 15 minutes, extract them under micro-pressure for 35 minutes, pack them into packaging bags with a capacity of 100ml, sterilize them at a high temperature of 100℃ for 25 minutes, and store them at a low temperature below 20℃ and away from light, to complete the preparation of Sophora flavescens sitz bath solution.

[0036] Embodiment 2: According to the weight ratio, take 20g of Coptis chinensis, 20g of Phellodendron chinense, 20g of Rhubarb, 20g of Carthamus tinctorius, 1.5g of Borneolum, 30g of Sanguisorba officinalis, 30g of Sophora flavescens, 20g of Kochia scoparia, 20g of Cnidium monnieri, 20g of Polygonum cuspidatum, 20g of Angelica dahurica, 20g of Sappan wood, 20g of Bletilla striata, and 3g of Catechu, wash and dry them, put them into medicine bags, soak them with water in a Chinese medicine decoction machine for 20 minutes, extract them under micro-pressure for 40 minutes, divide them into packaging bags with a capacity of 100ml, sterilize them at a high temperature of 100℃ for 30 minutes, and store them at a low temperature below 20℃ and away from light to complete the preparation of Sophora flavescens sitz bath solution.

[0037] Embodiment 3: According to the weight ratio, take 25g of Coptis chinensis, 25g of Phellodendron chinense, 25g of Rhubarb, 25g of Carthamus tinctorius, 2g of Borneolum, 35g of Sanguisorba officinalis, 35g of Sophora flavescens, 25g of Kochia scoparia, 25g of Cnidium monnieri, 25g of Polygonum cuspidatum, 25g of Angelica dahurica, 25g of Sappan wood, 25g of Bletilla striata, and 4g of Catechu, wash and dry them, put them into medicine bags, soak them with water in a Chinese medicine decoction machine for 25 minutes, extract them under micro-pressure for 45 minutes, divide them into packaging bags with a capacity of 100ml, sterilize them at a high temperature of 100℃ for 35 minutes, and store them at a low temperature below 20℃ and away from light to complete the preparation of Sophora flavescens sitz bath solution.

[0038] When using: [Usage and Dosage] 250ml / time, 2 times / day, sitz bath.

[0039] [Note] The temperature of the sitz bath should be around 40°C. Avoid spicy, greasy, raw or cold food during treatment.

[0040] The results of some clinical trials of the present invention are compared as follows: Experimental content: 1 Clinical Data 1.1 General data: 100 patients with mixed hemorrhoids after surgery admitted to the anorectal department of our hospital from June 2022 to December 2022 were selected and divided into two groups by random number table method, 50 cases in each group. Among them, the number of male and female patients in the control group was 28 and 22, respectively; the age ranged from 25 to 72 years old, with an average of (48.09±3.65) years old; the degree of internal hemorrhoids: 26 cases of grade III and 24 cases of grade IV. The number of male and female patients in the observation group was 26 and 24, respectively; the age ranged from 21 to 73 years old, with an average of (50.12±4.23) years old; the degree of internal hemorrhoids: 27 cases of grade III and 23 cases of grade IV. There was no statistically significant difference in the general data of the two groups of patients (P>0.05).

[0041] 1.2 Inclusion criteria: 1) Meet the relevant diagnostic criteria for mixed hemorrhoids in the "Guidelines for the Clinical Diagnosis and Treatment of Hemorrhoids", and the internal hemorrhoids are graded as III-IV; 2) Meet the relevant diagnostic criteria for hemorrhoids in the "Guidelines for the Diagnosis and Treatment of Common Diseases in Anorectal Department of Traditional Chinese Medicine", and be diagnosed as damp-heat descending type, with bright red blood in the stool, large amount of blood, prolapse of the anus, which can be retracted by itself, and burning sensation in the anus; red tongue, yellow and greasy tongue coating, and stringy and rapid pulse; 3) Age 20-75 years, regardless of gender; 4) Meet the surgical indications and have no contraindications to surgery; 5) Patients give informed consent.

[0042] 1.3 Exclusion criteria 1) Patients with other anorectal diseases such as perianal abscess, anal fistula, constipation or tumor; 2) Patients with serious underlying diseases; 3) Patients with syphilis, condyloma acuminatum and other diseases; 4) Patients with allergic constitution.

[0043] 2 Methods 2.1 Treatment methods: Both groups of patients were given mixed hemorrhoids external stripping and internal ligation after surgery, and routine anti-infection, hemostasis, analgesia and other symptomatic treatments were given after surgery. Patients in the control group were given compound potassium permanganate at a ratio of 1:5000 added to hot water, 1000 mL sitz bath at 80°C, 2 times / day, 30 minutes / time, for 7 days. The observation group used self-made Sophora flavescens sitz bath solution, the specific formula included: 20g of Coptis chinensis, 20g of Phellodendron chinense, 20g of Rhubarb, 20g of Carthamus tinctorius, 1.5g of Borneol, 30g of Sanguisorba officinalis, 30g of Sophora flavescens, 20g of Kochia scoparia, 20g of Cnidium monnieri, 20g of Polygonum cuspidatum, 20g of Angelica dahurica, 20g of Sappan wood, 20g of Bletilla striata, and 3g of Catechu. The above drugs were soaked in 3000mL of water for 30min, and the liquid was decocted to 1500mL. Hot steam was performed first, and when the temperature dropped to an appropriate level, a sitz bath was performed for 30min, once a day. Both groups of patients were treated for 7 consecutive days.

[0044] 2.2 The efficacy standards shall be evaluated in accordance with the relevant efficacy standards in the "Guiding Principles for Clinical Research of New Chinese Medicines".

[0045] 2.3 Observation indexes 1) Anal pain degree: The VAS scoring method was used to evaluate the anal pain degree of the two groups of mixed hemorrhoid surgery patients before and after medication, with a score of 0-10 points; 0 points for no pain; 1-3 points for mild pain, tolerable, no medication required for pain relief, and pain only felt during dressing changes or defecation; 4-6 points: continuous pain, pain affecting sleep, pain relief requires pain relief, pain aggravates during dressing changes or defecation, and even produces fear; 7-10 points: severe pain, auxiliary analgesics are difficult to relieve pain, sleepless nights, and unbearable. 2) Anal margin edema score: The anal margin edema of the two groups of mixed hemorrhoid surgery patients was evaluated before and after treatment, 0 points: no edema; 1 point: edema area <0.5cm; 2 points: edema area 0.5-1.0cm; 3 points: edema area 1.0-2.0cm; 4 points: edema area ≥2.0cm.

[0046] 2.4 Statistical methods The data were analyzed using SPSS 20.0. The quantitative data were expressed as mean ± standard deviation ( ±s) were used for t test; count data were used for X2 test; P < 0.05 indicated that the difference was statistically significant.

[0047] 3 Results 3.1 Comparison of efficacy between the two groups After 7 days of treatment, 27 cases of potassium permanganate sitz bath treatment in the control group showed marked effect, 15 cases showed effective results, and the total effective rate was 84.0%; 36 cases of Chinese medicine fumigation sitz bath treatment in the observation group showed marked effect, 12 cases showed effective results, and the total effective rate was 96.0%. The efficacy of the observation group was better than that of the control group (P<0.05). See Table 1.

[0048] Table 1 Comparison of efficacy between the two groups of patients [cases (%)]

[0049] Note: Compared with the control group, #P<0.05 3.2 Comparison of anal pain scores between the two groups at 1 and 7 days after surgery is shown in Table 2. The anal pain score of the control group was (6.02±1.46) points at 1 day after surgery, which dropped to (3.20±0.63) points at 7 days after surgery; the anal pain score of the observation group was (6.19±1.33) points at 11 days after surgery, which dropped to (1.41±0.59) points at 7 days after surgery; there was no significant difference in the scores between the two groups at 1 day after surgery, but the score of the observation group was significantly lower than that of the control group at 7 days after surgery (P<0.05).

[0050] Table 2 Comparison of perianal pain scores between the two groups at 1 and 7 days after surgery ( ±s, minutes)

[0051] Note: Compared with 1 day after surgery, *P<0.05; compared with the control group, #P<0.05 3.3 Comparison of the degree of anal verge edema between the two groups at 1 and 7 days after surgery is shown in Table 3. The anal verge edema score of the control group was (2.76±0.41) points at 1 day after surgery, which decreased to (0.82±0.12) points at 7 days after surgery; the anal verge edema score of the observation group was (2.68±0.39) points at 1 day after surgery, which decreased to (0.33±0.09) points at 7 days after surgery; there was no significant difference in the scores between the two groups at 1 day after surgery, and the score of the observation group was significantly lower than that of the control group at 7 days after surgery (P<0.05).

[0052] Table 3 Comparison of anal edema degree between the two groups before and after treatment ( ±s, minutes)

[0053] Note: Compared with 1 day after surgery, *P<0.05; compared with the control group, #P<0.05 4 Discussion The results of this study showed that the total effective rate of the observation group was 96.0% after 7 days of treatment, which was higher than 84.0% in the control group. After 7 days of treatment, the perianal pain scores and anal edema scores of the two groups of patients after mixed hemorrhoid surgery were lower than those before treatment (P<0.05), and those of the observation group were lower than those of the control group (P<0.05). This suggests that homemade Sophora flavescens sitz bath solution has a significant effect on the treatment of patients after mixed hemorrhoid surgery, which can relieve perianal pain and anal edema and promote wound healing.

[0054] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. Sophora flavescens sitz bath liquid, characterized in that: The invention is prepared from the following raw material drug components in the following weight ratio: 15-25g of coptis root, 15-25g of phellodendron, 15-25g of rhubarb, 15-25g of safflower, 1-2g of borneol, 25-35g of sanguisorba officinalis, 25-35g of sophora flavescens, 15-25g of kochia scoparia, 15-25g of cnidium monnieri, 15-25g of polygonum cuspidatum, 15-25g of angelica dahurica, 15-25g of sappan wood, 15-25g of bletilla striata and 2-4g of catechu.

2. The Sophora flavescens sitz bath liquid according to claim 1, characterized in that: The invention is prepared from the following raw material drug components in the following weight ratio: 15g of coptis root, 15g of phellodendron, 15g of rhubarb, 15g of safflower, 1g of borneol, 25g of sanguisorba officinalis, 25g of sophora flavescens, 15g of kochia fruit, 15g of cnidium monnieri, 15g of polygonum cuspidatum, 15g of angelica dahurica, 15-25g of sappan wood, 15g of bletilla striata and 2g of catechu.

3. The Sophora flavescens sitz bath liquid according to claim 1, characterized in that: The invention is prepared from the following raw material drug components in the following weight ratio: 20g of coptis root, 20g of phellodendron, 20g of rhubarb, 20g of safflower, 1.5g of borneol, 30g of sanguisorba officinalis, 30g of sophora flavescens, 20g of kochia scoparia, 20g of cnidium monnieri, 20g of polygonum cuspidatum, 20g of angelica dahurica, 20g of sappan wood, 20g of bletilla striata, and 3g of catechu.

4. The Sophora flavescens sitz bath liquid according to claim 1, characterized in that: The invention is prepared from the following raw material drug components in the following weight ratio: 25g of coptis root, 25g of phellodendron, 25g of rhubarb, 25g of safflower, 2g of borneol, 35g of sanguisorba officinalis, 35g of sophora flavescens, 25g of kochia fruit, 25g of cnidium monnieri, 25g of polygonum cuspidatum, 25g of angelica dahurica, 25g of sappan wood, 25g of bletilla striata, and 4g of catechu.

5. The method for preparing the Sophora flavescens sitz bath liquid according to any one of claims 1 to 4, characterized in that: The following steps are involved: Step 1: Take the above medicinal materials in corresponding proportions according to the weight ratio, wash and set aside; Step 2: Use drying equipment to dry the washed medicinal materials in step 1, and put them into medicine bags for decoction for later use; Step 3: Place the medicine bag filled with medicinal materials in step 2 into a Chinese medicine decoction machine, add an appropriate amount of water to soak for 15-25 minutes, and extract under slight pressure for 35-45 minutes; Step 4: Pack the medicinal liquid extracted in step 3 into packaging bags and sterilize them at 100° C. for 25-35 minutes to complete the preparation of the Sophora flavescens sitz bath solution.

6. The method for preparing the Sophora flavescens sitz bath liquid according to claim 5, characterized in that: The capacity of the packaging bag in step 3 is 250 ml.

7. The method for preparing the Sophora flavescens sitz bath liquid according to claim 5, characterized in that: The drug solution prepared in step 4 and packaged in the packaging bag is stored in a low temperature environment below 20° C. and away from light.

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