Design method and system of RFQ accelerator for medical isotope production

By optimizing the structural parameters of the RFQ accelerator and high-frequency design, combined with cooling channel optimization, an ultra-high frequency normal temperature linear accelerator system is formed, which solves the problems of low accelerator flow and high cost in the existing technology, and achieves efficient isotope production.

CN119967694AActive Publication Date: 2025-05-09INST OF MODERN PHYSICS CHINESE ACADEMY OF SCI
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Patent Information

Application Number
CN202411809556.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-10
Publication Date
2025-05-09
Estimated Expiration
2044-12-10

AI Technical Summary

Technical Problem

The prior art problems of low flow strength, high cost and high manufacturing cost of accelerators in medical isotope production.

Method used

Design a design method for RFQ accelerator for medical isotope production. By determining the target operating frequency range, the structural parameters of the RFQ accelerator are optimized, and combined with high-frequency design and cooling channel optimization, an ultra-high frequency normal temperature linear accelerator system is formed.

Benefits of technology

It improves the transmission efficiency of the α beam current, shortens the length of the accelerator, reduces production costs, and increases isotope yield.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of medical treatment, and provides a design method and system of an RFQ accelerator for medical isotope production, and the design method comprises the steps: determining a target working frequency range of the RFQ accelerator; based on the target working frequency range, optimizing structure parameters of the RFQ accelerator, and determining an optimization dynamic design scheme of the RFQ accelerator; performing high-frequency design on the structure parameters of the RFQ accelerator, and determining a high-frequency design scheme of the RFQ accelerator; optimizing structural parameters of a cooling flow channel in the RFQ accelerator, determining a physical design scheme of the RFQ accelerator, and obtaining the RFQ accelerator for medical isotope production. By selecting the optimal working frequency range of the RFQ accelerator and optimizing the structural parameters of the RFQ accelerator under the optimal working frequency, the length of the RFQ accelerator can be shortened, the production cost can be reduced, and the transmission efficiency of the alpha beam can be improved.
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Description

Technical Field

[0001] The present invention relates to the field of medical technology, and in particular to a design method of an RFQ accelerator for producing medical isotopes and an ultra-high frequency room temperature linear accelerator system. Background Art

[0002] Targeted alpha particle therapy (TAT) is a type of radioisotope targeted therapy. Compared with beta nuclides, alpha nuclides have a larger mass number, a shorter range, and a higher linear energy transfer density in the body, so they have stronger cytotoxicity in biological tissues. These characteristics enable alpha nuclides to show unique advantages in the treatment of hypoxic tumors, microtumors, scattered tumors, and micrometastatic tumors. There are fewer alpha isotopes suitable for targeted therapy, one of which is 211 At, 211 At has a suitable half-life (T 1 / 2 =7.2h); high biological effect and radiation toxicity, causing irreversible damage to tumor cell DNA within its range of action; simple decay, only second-order α decay, and no obvious recoil effect, so it is considered to be a high-quality clinical targeted α particle therapy nuclide.

[0003] Currently, accelerators for producing isotopes include cyclotrons and linear accelerators. For cyclotrons, the average flux is about tens of μA. To accelerate the α beam to 26-70 MeV, the diameter of the cyclotron needs to be about 3-8 meters. The flux of the cyclotron is relatively low, resulting in a low yield of isotopes.

[0004] Linear accelerators are mainly divided into superconducting linear accelerators and low-frequency, normal-temperature linear accelerators. For superconducting linear accelerators, the acceleration gradient is high and the average flux can reach tens of mA, but in order to achieve the superconducting state, a cryostat is introduced, so its overall length is long, and the manufacturing and operating costs are relatively high. For low-frequency, normal-temperature linear accelerators, the average flux can reach several mA, but due to the low operating frequency and low acceleration gradient, usually 2-3MV / m, the acceleration beam needs to be accelerated to 28-30MeV. The length of the acceleration part is ~12m, and the low operating frequency will make the lateral size of the cavity large, resulting in higher manufacturing costs. Summary of the invention

[0005] In view of the above problems, the purpose of the present invention is to provide a design method of an RFQ accelerator for medical isotope production and an ultra-high frequency room temperature linear accelerator system, which can improve beam transmission efficiency and reduce production costs.

[0006] The present invention provides a design method of an RFQ accelerator for producing medical isotopes, comprising the following steps:

[0007] Determine the target operating frequency range of the RFQ accelerator;

[0008] Based on the target operating frequency range, optimizing the structural parameters of the RFQ accelerator to determine a first optimization parameter, wherein the first optimization parameter is used to determine an optimized dynamic design scheme of the RFQ accelerator;

[0009] Based on the optimized dynamic design scheme, high-frequency design is performed on the structural parameters of the RFQ accelerator to determine second optimized parameters, where the second optimized parameters are used to determine the high-frequency design scheme of the RFQ accelerator;

[0010] Based on the high-frequency design scheme, optimizing the structural parameters of the cooling channel in the RFQ accelerator to obtain third optimized parameters, wherein the third optimized parameters are used to determine the physical design scheme of the RFQ accelerator;

[0011] Based on the physical design scheme, an RFQ accelerator for medical isotope production is obtained.

[0012] According to a design method of an RFQ accelerator for medical isotope production provided by the present invention, the step of determining a target operating frequency range of the RFQ accelerator comprises:

[0013] Based on the lateral stability conditions of the RFQ accelerator, the stable operating frequency range and minimum aperture range corresponding to the boundary of the lateral stability region are determined;

[0014] Determining an optimal operating frequency range from the stable operating frequency range;

[0015] The optimal operating frequency range is determined as the target operating frequency range.

[0016] According to a design method of an RFQ accelerator for producing medical isotopes provided by the present invention, the structural parameters of the RFQ accelerator are optimized based on the target operating frequency range to determine the first optimization parameter, including:

[0017] Based on the target operating frequency range, determining a first key factor affecting the ignition coefficient of the RFQ accelerator, and optimizing the structural parameters of the RFQ accelerator based on the first key factor to obtain first initial optimization parameters;

[0018] Determining a second key factor causing insufficient lateral focusing of the RFQ accelerator, and optimizing the structural parameters of the RFQ accelerator based on the second key factor to obtain second initial optimization parameters;

[0019] Determining a third key factor that causes the RFQ accelerator to be too long, and optimizing the structural parameters of the RFQ accelerator based on the third key factor to obtain third initial optimization parameters;

[0020] Determining a fourth key factor that causes low beam transmission efficiency, and optimizing the structural parameters of the RFQ accelerator based on the fourth key factor to obtain fourth initial optimization parameters;

[0021] The fourth initial optimization parameter is determined as the first optimization parameter.

[0022] According to a design method of an RFQ accelerator for producing medical isotopes provided by the present invention, based on the target operating frequency range, a first key factor affecting the ignition coefficient of the RFQ accelerator is determined, and based on the first key factor, the structural parameters of the RFQ accelerator are optimized to obtain first initial optimization parameters, including:

[0023] Based on the Kilpatrick criterion, determining a range of the Kilpatrick field corresponding to the target operating frequency range;

[0024] Determining a maximum surface electric field range based on a preset value of the RFQ accelerator sparking coefficient and a range of the Kilpatrick field;

[0025] Based on the relationship between the maximum surface electric field and the inter-electrode voltage of the RFQ accelerator, determining the inter-electrode voltage range corresponding to the maximum surface electric field range;

[0026] The maximum surface electric field range and the inter-electrode voltage range are determined as the first initial optimization parameters.

[0027] According to a design method of an RFQ accelerator for medical isotope production provided by the present invention, determining a second key factor that causes insufficient lateral focusing of the RFQ accelerator, and optimizing the structural parameters of the RFQ accelerator based on the second key factor to obtain second initial optimization parameters, comprises:

[0028] Determine the acceleration efficiency range based on formula (1) and formula (2);

[0029] B=eλ 2 XV / γM 0 c 2 a 2 (1)

[0030] X=1-AI 0 (ka)(2)

[0031] Where A represents the acceleration efficiency, B represents the lateral focusing strength, X represents the lateral focusing factor, a represents the minimum aperture, V represents the inter-electrode voltage, and λ represents the wavelength; β represents the particle speed; M 0represents the particle rest mass; c represents the speed of light; a represents the minimum aperture of RFQ; I 0 represents the zero-order Bessel function; L represents the unit length;

[0032] The acceleration efficiency range is determined as a second initial optimization parameter.

[0033] According to a design method of an RFQ accelerator for medical isotope production provided by the present invention, a third key factor causing the length of the RFQ accelerator to be too long is determined, and the structural parameters of the RFQ accelerator are optimized based on the third key factor to obtain third initial optimization parameters, including:

[0034] Based on the preset values ​​of field leveling adjustment, beam transmission efficiency, and sparking coefficient, a beam dynamics simulation calculation is performed on the RFQ accelerator to obtain a length range of the RFQ accelerator;

[0035] Based on the length range and the inter-electrode voltage range, determining an optimal length corresponding to an optimal inter-electrode voltage in the inter-electrode voltage range;

[0036] The optimal length is determined as a third initial optimization parameter.

[0037] According to a design method of an RFQ accelerator for producing medical isotopes provided by the present invention, based on the optimized kinetic design scheme, a high-frequency design is performed on the structural parameters of the RFQ accelerator to determine the second optimized parameters, including:

[0038] Comparing the power losses of RFQ accelerators with different preset structures, and determining the preset structure with the best power as the initial structure of the RFQ accelerator;

[0039] Performing field-level tuning design on the initial structure to obtain a target structure of the RFQ accelerator;

[0040] The target structure is determined as a second optimization parameter.

[0041] According to a design method of an RFQ accelerator for producing medical isotopes provided by the present invention, based on the high-frequency design scheme, the structural parameters of the cooling channel in the RFQ accelerator are optimized to obtain the third optimized parameters, including:

[0042] Perform high-frequency simulation calculations on the RFQ accelerator to determine the main heating locations of the RFQ accelerator cavity;

[0043] Based on the main parts, on the premise of ensuring the mechanical strength and stability of the RFQ accelerator, the cooling channel structural parameters in the RFQ accelerator cavity are designed, and the cooling channel structural parameters are determined as the third optimization parameters.

[0044] The present invention also provides an ultra-high frequency room temperature linear accelerator system for producing medical isotopes, comprising:

[0045] An alpha ion source, used to generate an alpha beam with a high peak current, wherein the energy of the alpha beam is 10-20 keV and the current intensity of the alpha beam is 10-15 emA;

[0046] An RFQ accelerator is connected to the α ion source through a low-energy transmission line, the RFQ accelerator is used to focus, bunch and accelerate the α beam, the frequency of the RFQ accelerator is 700-850 MHz, and the α beam energy at the outlet of the RFQ accelerator is 6-8 MeV;

[0047] A drift tube linear accelerator is connected to the RFQ accelerator, the frequency of the drift tube linear accelerator is 700-850 MHz, and the drift tube linear accelerator accelerates the alpha beam with high peak current intensity output by the RFQ accelerator.

[0048] According to an ultra-high frequency room temperature linear accelerator system for medical isotope production provided by the present invention, the RFQ accelerator and the drift tube linear accelerator operate at a high duty cycle of 1%-2%, with an average beam intensity of 100-200eμA, the RFQ accelerator adopts a quadrilateral four-wing structure, and the drift tube linear accelerator adopts a cross-type drift tube structure.

[0049] The design method of the RFQ accelerator for medical isotope production provided in an embodiment of the present invention can shorten the length of the RFQ accelerator, reduce the production cost, and improve the transmission efficiency of the alpha beam by selecting the optimal operating frequency range of the RFQ accelerator and optimizing the structural parameters of the RFQ accelerator at the optimal operating frequency. BRIEF DESCRIPTION OF THE DRAWINGS

[0050] In order to more clearly illustrate the technical solutions in the present invention or the prior art, a brief introduction will be given below to the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0051] Figure 1 This is one of the flow diagrams of the design method of the RFQ accelerator for medical isotope production provided by the present invention.

[0052] Figure 2 This is the second flow chart of the design method of the RFQ accelerator for medical isotope production provided by the present invention.

[0053] Figure 3 It is a schematic diagram of the stable operating frequency range and the minimum aperture range corresponding to the boundary of the lateral stable zone provided by the present invention.

[0054] Figure 4 This is the third flow chart of the design method of the RFQ accelerator for medical isotope production provided by the present invention.

[0055] Figure 5 This is the fourth flow chart of the design method of the RFQ accelerator for medical isotope production provided by the present invention.

[0056] Figure 6 This is the fifth flow chart of the design method of the RFQ accelerator for medical isotope production provided by the present invention.

[0057] Figure 7 It is a schematic diagram of the inter-electrode voltage variation curve with the number of units provided by the present invention.

[0058] Figure 8 It is a schematic diagram of the horizontal and vertical phase comparison before and after the longitudinal acceptance optimization provided by the present invention.

[0059] Fig. 9 This is the sixth flow chart of the design method of the RFQ accelerator for medical isotope production provided by the present invention.

[0060] Fig.10 This is the seventh flow chart of the design method of the RFQ accelerator for medical isotope production provided by the present invention.

[0061] Fig.11 It is a schematic diagram of the structure of an ultra-high frequency room temperature linear accelerator system for producing medical isotopes provided by the present invention.

[0062] Fig.12 The invention provides an RFQ accelerator with an octagonal four-wing structure.

[0063] Fig.13 The invention provides an RFQ accelerator with a quadrilateral four-wing structure.

[0064] Fig.14 It is a schematic diagram comparing the low high-frequency power loss of the RFQ accelerators with an octagonal four-wing structure and a quadrilateral four-wing structure provided by the present invention, wherein power oct represents the octagonal four-wing structure, and power tet represents the quadrilateral four-wing structure.

[0065] Fig.15 It is a schematic structural diagram of the cooling channel of the CH-DTL accelerator provided by the present invention.

[0066] Fig.16It is a structural schematic diagram of the electronic device provided by the present invention.

[0067] Reference numerals:

[0068] 10. α ion source; 20. Low energy transmission line; 30. Radio frequency quadrupole field accelerator; 40. Drift tube linear accelerator; 50. High energy transmission system;

[0069] 41. Acceleration chamber; 42. Main beam; 43. Support rod; 44. Drift tube; 45. Cooling water channel. DETAILED DESCRIPTION

[0070] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the drawings of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0071] Combine the following Figure 1-Figure 10 The design method of the RFQ accelerator for medical isotope production of the present invention is described.

[0072] The embodiment of the present invention provides a design method of an RFQ accelerator for producing medical isotopes, such as Figure 1 As shown, the design method includes the following steps:

[0073] Step 100: Determine a target operating frequency range of a radio frequency quadrupole (RFQ).

[0074] Among them, the radio frequency quadrupole accelerator (RFQ accelerator) can adopt an ultra-high frequency RFQ accelerator, select the best operating frequency range of the ultra-high frequency RFQ accelerator, and use the best operating frequency range as the target operating frequency range.

[0075] Step 200: Optimize the structural parameters of the RFQ accelerator based on the target operating frequency range to determine a first optimization parameter, where the first optimization parameter is used to determine an optimized dynamic design scheme for the RFQ accelerator.

[0076] It is understandable that the RFQ accelerator will cause physical problems within the target operating frequency range. The physical problems are studied and solutions are proposed. The solution can be to design and optimize the structural parameters of the RFQ accelerator to determine the first optimization parameters. According to the first optimization parameters, the optimized dynamic design scheme of the RFQ accelerator can be obtained.

[0077] Step 300: Based on the optimized dynamic design scheme, high-frequency design is performed on the structural parameters of the RFQ accelerator to determine second optimized parameters, where the second optimized parameters are used to determine the high-frequency design scheme of the RFQ accelerator.

[0078] It can be understood that, based on the optimized dynamic design scheme, the structural parameters of the RFQ accelerator can be designed at high frequency for the purpose of low power loss and easy field tuning, thereby determining the second optimized parameters, and the high-frequency design scheme of the RFQ accelerator can be obtained according to the second optimized parameters.

[0079] Step 400: Based on the high-frequency design solution, the structural parameters of the cooling channel in the RFQ accelerator are optimized to obtain third optimized parameters, and the third optimized parameters are used to determine the physical design solution of the RFQ accelerator.

[0080] It can be understood that based on the high-frequency design scheme, the cooling channel in the RFQ accelerator is optimized to obtain the physical design scheme of the RFQ accelerator.

[0081] Step 500: Based on the physical design solution, obtain an RFQ accelerator for medical isotope production.

[0082] It can be understood that, according to this physical design scheme, the RFQ accelerator process scheme design is completed, so that an RFQ accelerator that can meet the production of medical isotopes can be obtained.

[0083] The design method of the RFQ accelerator for medical isotope production provided in an embodiment of the present invention can shorten the length of the RFQ accelerator, reduce the production cost, and improve the transmission efficiency of the alpha beam by selecting the optimal operating frequency range of the RFQ accelerator and optimizing the structural parameters of the RFQ accelerator at the optimal operating frequency.

[0084] Optional, such as Figure 2 As shown, step 100 may specifically include the following steps:

[0085] Step 110: Based on the lateral stability condition of the RFQ accelerator, determine the stable operating frequency range and the minimum aperture range corresponding to the boundary of the lateral stability region.

[0086] It can be understood that based on the transverse stability requirements of the RFQ accelerator, the influence of the particle velocity and modulation factor at the end of the RFQ accelerator's focusing section on the boundary of the transverse stability zone is explored, and the stable operating frequency and minimum aperture range corresponding to the boundary of the transverse stability zone are obtained.

[0087] Step 120: Determine an optimal operating frequency range from the stable operating frequency range.

[0088] It can be understood that the optimal operating frequency range and the minimum aperture range are determined from the stable operating frequency range based on process capability, gain length, beam acceptance, and power consumption.

[0089] Step 130: Determine the optimal operating frequency range as the target operating frequency range.

[0090] Optionally, in the above step 110, the stable operating frequency range and the minimum aperture range corresponding to the boundary of the lateral stable region are obtained, such as Figure 3 As shown, beta represents the speed of the particle in units of the speed of light, and m represents the modulation factor. Figure 3 The five curves in the figure represent the stable zone boundaries of beta and m at the end of different bunching segments. The points below the stable boundary curves are all stable points, thereby determining the power consumption (operating frequency), machining accuracy and the boundary of the stable zone (minimum aperture). Preferably, the optimal operating frequency range and minimum aperture range used in this embodiment are 714MHz-850MHz and 0.8cm-0.95cm, respectively.

[0091] Optionally, the target operating frequency range of this embodiment is equivalent to increasing the operating frequency compared to the existing RFQ accelerator; a series of physical problems caused by the increase in the operating frequency of the RFQ accelerator are studied, the most important of which is the weakening of the lateral focusing of the RFQ accelerator, and solutions are proposed to perform parameter design and optimization of the ultra-high frequency RFQ accelerator to obtain an optimized dynamic design solution. Figure 4 As shown, step 200, based on the target operating frequency range, optimizes the structural parameters of the RFQ accelerator to determine the first optimization parameter, including the following steps:

[0092] Step 210: Based on the target operating frequency range, determine the first key factor affecting the ignition coefficient of the RFQ accelerator, and optimize the structural parameters of the RFQ accelerator based on the first key factor to obtain first initial optimization parameters.

[0093] It can be understood that, according to the target operating frequency range, the key factors affecting the ignition coefficient of the ultra-high frequency RFQ accelerator are determined, and the structural parameters of the ultra-high frequency RFQ accelerator are optimized based on the various key factors, so as to obtain the first initial optimization parameters.

[0094] Step 220: determine a second key factor that causes insufficient lateral focusing of the RFQ accelerator, and optimize the structural parameters of the RFQ accelerator based on the second key factor to obtain second initial optimization parameters.

[0095] It can be understood that the key factors leading to insufficient lateral focusing of the ultra-high frequency RFQ accelerator are determined, and the structural parameters of the ultra-high frequency RFQ accelerator are optimized based on the key factors, so as to obtain the second initial optimization parameters.

[0096] Step 230: determine a third key factor that causes the RFQ accelerator to be too long, and optimize the structural parameters of the RFQ accelerator based on the third key factor to obtain third initial optimization parameters.

[0097] It is understandable that the key factors that cause the length of the ultra-high frequency RFQ accelerator to be too long are determined, and the structural parameters of the ultra-high frequency RFQ accelerator are optimized based on the various key factors. For example, a variable voltage solution can be used to improve the acceleration efficiency, and the length of the ultra-high frequency RFQ accelerator is controlled within about 6 times the wavelength, thereby obtaining the third initial optimization parameter. It should be noted here that the length of the ultra-high frequency RFQ accelerator is expected to be controlled within about 6 times the wavelength. In this embodiment, the length of the ultra-high frequency RFQ accelerator is controlled within the range of about 5 times the wavelength to about 6 times the wavelength; of course, in other embodiments, the length of the ultra-high frequency RFQ accelerator is reasonably designed according to actual needs.

[0098] Step 240: determine a fourth key factor that causes low beam transmission efficiency, and optimize the structural parameters of the RFQ accelerator based on the fourth key factor to obtain fourth initial optimization parameters.

[0099] For example, the beam current is 4 He 2+ beam current, determine the cause 4 He 2+ The key factors of low beam transmission efficiency are identified, and the structural parameters of the ultra-high frequency RFQ accelerator are optimized based on the key factors to obtain the fourth initial optimization parameters;

[0100] Step 250: Determine the fourth initial optimization parameter as the first optimization parameter.

[0101] It is understandable that the optimized dynamic design scheme of the RFQ accelerator is obtained according to the fourth initial optimization parameter. It should be noted here that in other embodiments, part or all of the parameters related to the structural parameters of the RFQ accelerator in the first initial optimization parameter, the second initial optimization parameter, the third initial optimization parameter, and the fourth initial optimization parameter can be used as the first optimization parameter to obtain the optimized dynamic design scheme.

[0102] Optional, such as Figure 5 As shown, step 210 may specifically include the following steps:

[0103] Step 211: Based on the Kilpatrick criterion, determine the range of the Kilpatrick field corresponding to the target operating frequency range.

[0104] It is understandable that WD Kilpatrick analyzed the data of RF breakdown and defined the conditions for no-breakdown operation. He proposed an equation to express the Kilpatrick result, which is often used in the design of room-temperature RF accelerator cavities. Usually, the known quantity is the design frequency of the cavity. This equation can be solved to obtain the Kilpatrick electric field E K , the formula is as follows:

[0105]

[0106] So the above equation is about the electric field E K The transcendental equation is numerically solved by iterative method to obtain E corresponding to frequency f K value.

[0107] In this embodiment, the Kilpatrick field corresponding to the target operating frequency range is in the range of 24.9 MV / m to 26.7 MV / m.

[0108] Step 212: Determine the maximum surface electric field range based on the preset value of the RFQ accelerator ignition coefficient and the range of the Kilpatrick field.

[0109] It is understood that by multiplying the range of the Kilpatrick field by the preset value of the spark coefficient, the range of the maximum surface electric field can be obtained. For example, the spark coefficient is 2.5, the range of the Kilpatrick field is 24.9MV / m to 26.7MV / m, and the maximum surface electric field range is 62.25MV / m to 66.75MV / m.

[0110] Step 213: Based on the relationship between the maximum surface electric field and the inter-electrode voltage of the RFQ accelerator, determine the inter-electrode voltage range corresponding to the maximum surface electric field range.

[0111] Specifically, based on the sparking coefficient of the RFQ accelerator, the relationship between the maximum surface electric field and the inter-electrode voltage of the RFQ accelerator is determined, and the relationship is Es=kV / (ma+a), wherein Es represents the maximum surface electric field, V represents the inter-electrode voltage, k represents the sparking coefficient, m represents the modulation factor, and a represents the minimum aperture.

[0112] Based on the above relationship between the maximum surface electric field and the inter-electrode voltage, the inter-electrode voltage range is determined. When the maximum surface electric field range is 62.25MV / m to 66.75MV / m, the inter-electrode voltage range is 54.59kV to 71.88kV.

[0113] Step 214: determine the maximum surface electric field range and the inter-electrode voltage range as the first initial optimization parameters.

[0114] It can be understood that the structural parameters of the RFQ accelerator are optimized based on the maximum surface electric field range and the inter-electrode voltage range.

[0115] Optionally, step 220 may be implemented in the following manner:

[0116] Based on the minimum aperture range, inter-electrode voltage range and lateral focusing requirements, the acceleration efficiency range is determined, and the acceleration efficiency range is determined as the second initial optimization parameter, so that the structural parameters of the RFQ accelerator are optimized based on the acceleration efficiency range.

[0117] Specifically, the acceleration efficiency range is determined based on formula (1) and formula (2);

[0118] B=eλ 2 XV / γM 0 c 2 a 2 (1)

[0119] X=1-AI 0 (ka)(2)

[0120] Where A represents the acceleration efficiency, B represents the lateral focusing strength, X represents the lateral focusing factor, a represents the minimum aperture, V represents the inter-electrode voltage, and λ represents the wavelength; β represents the particle speed; M 0 represents the particle rest mass; c represents the speed of light; a represents the minimum aperture of RFQ; I 0 represents the zero-order Bessel function; L represents the unit length.

[0121] In this embodiment, in order to improve the lateral focusing, the acceleration efficiency is calculated to be in the range of 0.18-0.19.

[0122] Optional, such as Figure 6 As shown, step 230 may specifically include the following steps:

[0123] Step 231: Based on the preset values ​​of field leveling, beam transmission efficiency, and sparking coefficient, a beam dynamics simulation calculation is performed on the RFQ accelerator to obtain the length range of the RFQ accelerator.

[0124] Among them, the preset value of the ignition coefficient is determined according to the requirements of the ignition coefficient.

[0125] Step 232: Based on the length range and the inter-electrode voltage range, determine the optimal length corresponding to the optimal inter-electrode voltage in the inter-electrode voltage range.

[0126] It can be understood that, based on the inter-electrode voltage range determined above, an investigation is conducted into how the cavity of the RFQ accelerator can achieve the optimal inter-electrode voltage, and the length corresponding to the optimal inter-electrode voltage in the inter-electrode voltage range is determined as the optimal length.

[0127] Step 233: Determine the optimal length as the third initial optimization parameter.

[0128] It can be understood that the structural parameters of the RFQ accelerator are optimized based on the optimal length.

[0129] Optionally, in step 231, based on dynamic simulation calculations, when the length of the RFQ accelerator is between 5 times the wavelength and 6 times the wavelength, field flatness adjustment is easier and a higher transmission efficiency is maintained. Therefore, the length range of the RFQ accelerator is between 5 times the wavelength and 6 times the wavelength.

[0130] Optionally, step 232 may be implemented in the following manner:

[0131] Based on dynamic simulation design, this embodiment adopts a variable voltage solution. Specifically, the first three sections of the RFQ accelerator (radial matching section, forming section, and bunching section) have weak lateral focusing. A stronger lateral focusing is provided by maintaining a constant inter-electrode voltage. The inter-electrode voltage is changed only in the acceleration section of the RFQ accelerator to shorten the length of the RFQ. That is, the first three sections of the RFQ accelerator use a constant voltage, and the acceleration section of the RFQ accelerator uses a variable voltage.

[0132] Specifically, the steps for determining the constant voltage value are as follows: first, the range of inter-electrode voltage that satisfies the Kilpatrick criterion is calculated according to the theoretical formula; second, within this range, a suitable voltage value is selected by comprehensively considering factors such as lateral focusing intensity and power consumption. In this embodiment, the voltage value selected as the constant voltage is 50.87 kV.

[0133] The steps for determining the maximum voltage value are as follows: first, the range of inter-electrode voltage that satisfies the Kilpatrick criterion is calculated according to the theoretical formula; second, within this range, a suitable voltage value is selected by comprehensively considering factors such as transverse focusing intensity, power consumption, RFQ length, beam transmission efficiency, etc. In this embodiment, the voltage value selected for the maximum voltage is 63.37 kV.

[0134] Based on the constant voltage value and the maximum voltage value, and after multiple simulation calculations, the voltage change curve is obtained, such as Figure 7 As shown in the figure, the voltage changes from 50.87 kV to 63.37 kV. It can be seen that the use of variable voltage solution can improve the acceleration efficiency and shorten the length of the RFQ accelerator, so that the length of the RFQ accelerator is controlled within about 6 times the wavelength. At this time, the field level adjustment of the RFQ accelerator cavity is easier.

[0135] Furthermore, step 240 can be implemented in the following manner:

[0136] The key factors that lead to the low alpha beam transmission efficiency are identified, and the structural parameters of the RFQ accelerator are optimized based on the key factors. Based on the optimization of the above structural parameters and the variable voltage design, the beam transmission efficiency of the accelerator is maximized to about 78.4%.

[0137] It should be noted that by optimizing the longitudinal acceptance through synchronous phase change, the longitudinal bunching is weakened in the bunching section, and the acceleration and transverse focusing capabilities are enhanced, thereby optimizing the transverse and longitudinal focusing, bunching and acceleration capabilities, realizing the confinement of the strong beam, and improving the RFQ beam transmission efficiency. After multiple simulations and calculations, Figure 8 As shown, with the previous parameters unchanged, the number of lost particles is reduced only by optimizing the synchronous phase evolution process, and the final beam transmission efficiency is increased to about 94.5%.

[0138] Optional, such as Fig. 9 As shown, step 300, based on the optimized dynamic design scheme, the structural parameters of the RFQ accelerator are designed at high frequency to determine the second optimized parameters, and the design is specifically designed for the purpose of low power loss and field flatness and easy tuning, which may include the following steps:

[0139] Step 310: compare the power losses of RFQ accelerators with different preset structures, and determine the preset structure with the optimal power as the initial structure of the RFQ accelerator.

[0140] Among them, different preset structures refer to the differences in the physical structures of the RFQ accelerator, which may be different cross-sectional shapes of the RFQ accelerator, such as an octagonal or quadrilateral structure, or different compositions of the RFQ accelerator, or other physical parameters such as the structural shapes and connection relationships of the components of the RFQ accelerator.

[0141] It can be understood that by comparing and analyzing the power losses of different preset structures, the one with the smallest power loss is the optimal power, and the preset structure with the optimal power is determined as the initial structure from multiple different preset structures.

[0142] Step 320: Perform field-level tuning design on the initial structure to obtain the target structure of the RFQ accelerator.

[0143] It can be understood that the structural field-level tuning design is performed on the initial structure to determine the optimal structural changes and realize the field-level design under the variable voltage field, thereby determining the optimal structure as the target structure of the RFQ accelerator.

[0144] Step 330: Determine the target structure as the second optimization parameter.

[0145] It can be understood that the high frequency design of the RFQ accelerator is determined based on the optimal structure.

[0146] In this embodiment, in step 310, the optimal power is 380-420 kW. In step 320, the optimal quadrupole field unevenness of the RFQ accelerator is <2%.

[0147] Optional, such as Fig.10 As shown, step 400, based on the high-frequency design solution, optimizes the structural parameters of the cooling channel in the RFQ accelerator to obtain the third optimized parameters, which may specifically include the following steps:

[0148] Step 410: Perform high-frequency simulation calculations on the RFQ accelerator to determine the main heating locations of the RFQ accelerator cavity.

[0149] Step 420: Based on the main parts, and on the premise of ensuring the mechanical strength and stability of the RFQ accelerator, the cooling channel structure parameters in the RFQ accelerator cavity are designed, and the cooling channel structure parameters are determined as the third optimization parameters.

[0150] It is understandable that based on the high-frequency design solution, the cooling channel of the RFQ accelerator is optimized, and deformation and stress analysis is performed to obtain a physical design solution. Specifically, the main parts that affect the heating of the RFQ accelerator cavity are determined through high-frequency simulation design of the RFQ accelerator; based on the main parts of the heating of the RFQ accelerator cavity determined, the cooling channel in the RFQ accelerator cavity is designed on the premise of ensuring the mechanical strength and stability of the RFQ accelerator, so that it can work at a higher duty cycle and make the deformation and stress meet the requirements, thereby obtaining a physical design solution.

[0151] Preferably, after designing the cooling channel structural parameters in the RFQ accelerator cavity, the RFQ working duty cycle can be 1%-2%, the temperature rise is less than 30° C., the deformation is less than 20 μm, and the stress is less than 40 MPa.

[0152] The present invention also provides an ultra-high frequency room temperature linear accelerator system for producing medical isotopes, such as Fig.11 As shown, the ultra-high frequency room temperature linear accelerator system includes an alpha ion source, a radio frequency quadrupole accelerator (RFQ accelerator) and a drift tube linear accelerator (Drift Tube Linac, DTL).

[0153] The α ion source 10 is used to generate an α beam with a high peak current intensity. The energy of the α beam is 10-20 keV, and the intensity of the α beam is 10-15 emA.

[0154] The RFQ accelerator is connected to the α ion source 10 through a low-energy transmission line 20. The RFQ accelerator is used to focus, bunch and accelerate the α beam. The frequency of the RFQ accelerator is 700-850 MHz, and the α beam energy at the outlet of the RFQ accelerator is 6-8 MeV. The low-energy transmission line 20 connects the α ion source 10 and the RFQ accelerator. The low-energy transmission line 20 is used to efficiently transmit the α beam provided by the ion source and match it to be injected into the RFQ accelerator.

[0155] The drift tube linear accelerator 40 (DTL accelerator) is connected to the RFQ accelerator. The frequency of the drift tube linear accelerator 40 is 700-850 MHz. The drift tube linear accelerator 40 adopts a cross-type drift tube structure. The drift tube linear accelerator 40 accelerates the high peak current intensity α beam output by the RFQ accelerator.

[0156] Specifically, the RFQ accelerator is designed using the design method of the RFQ accelerator used for medical isotope production, which effectively shortens the length of the RFQ accelerator and improves the transmission efficiency of the α beam, with an outlet peak flux of ~10emA; the DTL accelerator is used to further accelerate the high-peak flux α beam output by the RFQ accelerator. The DTL accelerator frequency is 700-850MHz, the outlet α beam energy is 28-30MeV, and the peak flux is ~10emA.

[0157] The ultra-high frequency room temperature linear accelerator system for medical isotope production provided in the embodiment of the present invention can provide an alpha particle beam with an energy of 28-30MeV and an average flux of 100-200eμA after the alpha beam generated by the alpha ion source 10 is accelerated by the RFQ accelerator and the DTL accelerator. It has the advantages of large peak and average beam intensities, high transmission efficiency, and small horizontal and vertical dimensions, which can increase the yield of isotopes and reduce the production cost of the equipment.

[0158] The ultra-high frequency room temperature linear accelerator system for medical isotope production provided by the embodiment of the present invention has a high acceleration gradient, the operating frequency of the RFQ accelerator can be 714-850MHz, and the RFQ accelerator is short, specifically about 6-7m, which is half the length of the existing low-frequency room temperature linear accelerator.

[0159] The ultra-high frequency room temperature linear accelerator system for medical isotope production provided by the embodiment of the present invention has a small lateral size, so that the processing cost is low; and because the operating frequency is increased, the lateral size can be reduced to 50% of the existing structure, reducing the accelerator processing and manufacturing cost.

[0160] It should be noted that the existing high-frequency room-temperature linear accelerators are mostly used to accelerate proton beams, and the maximum proton flux of the beam adjustment is about 1 μA, and the transmission efficiency is about 20-30%, which is relatively low; while the ultra-high frequency room-temperature linear accelerator system of the embodiment of the present invention has the characteristics of high average flux and high transmission efficiency, and can provide an alpha particle beam with a peak intensity of ~10emA with a transmission efficiency of more than 90%, which can effectively improve the medical isotope astatine-211 ( 211 At) production output.

[0161] Furthermore, the ultra-high frequency room temperature linear accelerator system of this embodiment also includes a high energy transmission system, which is connected to the drift tube linear accelerator. The drift tube linear accelerator is used to efficiently transmit the high peak value and average current of the α beam output by the drift tube linear accelerator to the target end, and reduce the peak power of the target beam, avoid thermal shock, and reduce the cooling pressure of the target cooling system, so that it can withstand an α beam of 100 to 200 eμA.

[0162] In one embodiment of the present invention, the α ion source may be a superconducting electron cyclotron resonance (ECR) source or a hybrid ECR source, and its operating frequency may be 18 GHz.

[0163] It is understandable that the ECR source at room temperature can provide an α beam of 1emA. When the beam intensity is large, the beam quality is relatively poor, which is not conducive to the transmission of the subsequent acceleration structure and limits the beam intensity at the exit. The present invention adopts a superconducting ECR source or a hybrid ECR source. The superconducting ECR source mainly refers to the coil and the hexapole iron both adopting the superconducting state, while the hybrid ECR source mainly refers to the coil adopting the superconducting state and the hexapole iron adopting the permanent magnet.

[0164] Optional, such as Fig.12 As shown, the RFQ accelerator can adopt an octagonal four-wing structure; Fig.13 As shown in FIG, the RFQ accelerator can also adopt a quadrilateral four-wing structure. Fig.14 As shown, Fig.14 In the figure, the abscissa theta represents the chord angle of the pole head, and the ordinate represents the Power cavity power. Compared with the octagonal four-wing structure, the high-frequency power loss of the quadrilateral four-wing structure is 6-10% lower, and it can operate at a higher duty cycle, thereby improving the average beam intensity. The average exit beam intensity is 100-200euA. In addition, the quadrilateral structure is more conducive to the field-flat tuning of the variable voltage design. Therefore, it is preferred that the RFQ accelerator adopts the quadrilateral four-wing structure.

[0165] According to an embodiment of the present invention, the DTL accelerator adopts a cross-rod drift tube structure, that is, the DTL accelerator is a cross-field drift tube accelerator (Crossed-Field Drift Tube Linear Accelerator, CH-DTL). By utilizing its cooling channel design, it can operate at a higher duty cycle and improve the average beam intensity. The average beam intensity at the CH-DTL accelerator outlet is 100 to 200 eμA.

[0166] It is understandable that, under the same chamber pressure, the power of the CH-DTL accelerator is about 17% higher than that of the heavy ion drift tube linear accelerator (IH-DTL). Correspondingly, the peak electric field of the CH-DTL accelerator is 10% lower than that of the IH-DTL accelerator, and the IH-DTL accelerator has about 6% to 10% of dipole due to its lateral asymmetry, while the CH-DTL accelerator of this embodiment does not have the problem of dipole at all. Therefore, from a structural point of view, the CH-DTL accelerator of this embodiment is more conducive to the flow channel design around the drift tube, and it is easier to achieve cooling of the drift tube, so that it can work at a higher duty cycle.

[0167] like Fig.15 As shown, the design scheme of the cooling channel of the CH-DTL accelerator of this embodiment is illustrated, wherein the CH-DTL accelerator includes an accelerating cavity 41, the inner wall of the accelerating cavity 41 has two opposite beams 42, a support rod 43 is provided between the two beams 42, a drift tube 44 is formed in the middle of the support rod 43, and a cooling water channel 45 is formed on the support rod 43. Even at a duty cycle of 10%, the maximum temperature rise on the accelerating cavity 41 is only 15 degrees, the maximum deformation is within 0.02mm, and the maximum stress is less than 20Mpa, which is more conducive to the design of the cooling channel around the drift tube.

[0168] Fig.16 An example of a physical structure diagram of an electronic device is shown in FIG. Fig.16As shown, the electronic device may include: a processor (Processor) 1610, a communication interface (CommunicationsInterface) 1620, a memory (Memory) 1630 and a communication bus 1640, wherein the processor 1610, the communication interface 1620, and the memory 1630 communicate with each other through the communication bus 1640. The processor 1610 can call the logic instructions in the memory 1630 to execute the design method of the RFQ accelerator for medical isotope production, which includes: determining a target operating frequency range of a radio frequency quadrupole accelerator (RFQ); based on the target operating frequency range, optimizing the structural parameters of the RFQ accelerator to determine a first optimization parameter, and the first optimization parameter is used to determine an optimized dynamic design scheme of the RFQ accelerator; based on the optimized dynamic design scheme, performing high-frequency design on the structural parameters of the RFQ accelerator to determine a second optimization parameter, and the second optimization parameter is used to determine a high-frequency design scheme of the RFQ accelerator; based on the high-frequency design scheme, optimizing the structural parameters of the cooling channel in the RFQ accelerator to obtain a third optimization parameter, and the third optimization parameter is used to determine a physical design scheme of the RFQ accelerator; based on the physical design scheme, obtaining an RFQ accelerator for medical isotope production.

[0169] In addition, the logic instructions in the above-mentioned memory 1630 can be implemented in the form of a software functional unit and can be stored in a computer-readable storage medium when it is sold or used as an independent product. Based on such an understanding, the technical solution of the present invention can be essentially or partly embodied in the form of a software product that contributes to the prior art. The computer software product is stored in a storage medium, including several instructions for a computer device (which can be a personal computer, a server, or a network device, etc.) to perform all or part of the steps of the methods of various embodiments of the present invention. The aforementioned storage medium includes: various media that can store program codes, such as a USB flash drive, a mobile hard disk, a read-only memory (ROM), a random access memory (RAM), a magnetic disk or an optical disk.

[0170] On the other hand, the present invention also provides a computer program product, which includes a computer program. The computer program can be stored on a non-transitory computer-readable storage medium. When the computer program is executed by a processor, the computer can execute the design method of an RFQ accelerator for medical isotope production provided by the above methods. The design method includes: determining a target operating frequency range of a radio frequency quadrupole accelerator (RFQ); based on the target operating frequency range, optimizing the structural parameters of the RFQ accelerator to determine a first optimization parameter, and the first optimization parameter is used to determine an optimized dynamic design scheme of the RFQ accelerator; based on the optimized dynamic design scheme, performing high-frequency design on the structural parameters of the RFQ accelerator to determine a second optimization parameter, and the second optimization parameter is used to determine a high-frequency design scheme of the RFQ accelerator; based on the high-frequency design scheme, optimizing the structural parameters of the cooling channel in the RFQ accelerator to obtain a third optimization parameter, and the third optimization parameter is used to determine a physical design scheme of the RFQ accelerator; based on the physical design scheme, obtaining an RFQ accelerator for medical isotope production.

[0171] On the other hand, the present invention also provides a non-transitory computer-readable storage medium having a computer program stored thereon, which, when executed by a processor, is implemented to execute the design method of an RFQ accelerator for medical isotope production provided by the above-mentioned methods, the design method comprising: determining a target operating frequency range of a radio frequency quadrupole accelerator (RFQ); based on the target operating frequency range, optimizing the structural parameters of the RFQ accelerator to determine a first optimization parameter, the first optimization parameter being used to determine an optimized dynamic design scheme of the RFQ accelerator; based on the optimized dynamic design scheme, performing high-frequency design on the structural parameters of the RFQ accelerator to determine a second optimization parameter, the second optimization parameter being used to determine a high-frequency design scheme of the RFQ accelerator; based on the high-frequency design scheme, optimizing the structural parameters of the cooling channel in the RFQ accelerator to obtain a third optimization parameter, the third optimization parameter being used to determine a physical design scheme of the RFQ accelerator; based on the physical design scheme, obtaining an RFQ accelerator for medical isotope production.

[0172] The device embodiments described above are merely illustrative, wherein the units described as separate components may or may not be physically separated, and the components shown as units may or may not be physical units, i.e., they may be located in one place, or they may be distributed on multiple network units. Some or all of the modules may be selected according to actual needs to achieve the purpose of the scheme of this embodiment. Those of ordinary skill in the art may understand and implement it without creative effort.

[0173] Through the description of the above implementation methods, those skilled in the art can clearly understand that each implementation method can be implemented by means of software plus a necessary general hardware platform, and of course, it can also be implemented by hardware. Based on this understanding, the above technical solution is essentially or the part that contributes to the prior art can be embodied in the form of a software product, and the computer software product can be stored in a computer-readable storage medium, such as ROM / RAM, a disk, an optical disk, etc., including a number of instructions for a computer device (which can be a personal computer, a server, or a network device, etc.) to execute the methods of each embodiment or some parts of the embodiment.

[0174] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A design method for an RFQ accelerator for medical isotope production, characterized in that: include: Determine the target operating frequency range of the RFQ accelerator; Based on the target operating frequency range, optimizing the structural parameters of the RFQ accelerator to determine a first optimization parameter, wherein the first optimization parameter is used to determine an optimized dynamic design scheme of the RFQ accelerator; Based on the optimized dynamic design scheme, high-frequency design is performed on the structural parameters of the RFQ accelerator to determine second optimized parameters, where the second optimized parameters are used to determine the high-frequency design scheme of the RFQ accelerator; Based on the high-frequency design scheme, optimizing the structural parameters of the cooling channel in the RFQ accelerator to obtain third optimized parameters, wherein the third optimized parameters are used to determine the physical design scheme of the RFQ accelerator; Based on the physical design scheme, an RFQ accelerator for medical isotope production is obtained.

2. The design method of the RFQ accelerator for medical isotope production according to claim 1, characterized in that: Determining the target operating frequency range of the RFQ accelerator includes: Based on the lateral stability conditions of the RFQ accelerator, the stable operating frequency range and minimum aperture range corresponding to the boundary of the lateral stability zone are determined; Determining an optimal operating frequency range from the stable operating frequency range; The optimal operating frequency range is determined as the target operating frequency range.

3. The design method of the RFQ accelerator for medical isotope production according to claim 2, characterized in that: Based on the target operating frequency range, optimizing the structural parameters of the RFQ accelerator to determine a first optimization parameter includes: Based on the target operating frequency range, determining a first key factor affecting the ignition coefficient of the RFQ accelerator, and optimizing the structural parameters of the RFQ accelerator based on the first key factor to obtain first initial optimization parameters; Determining a second key factor causing insufficient lateral focusing of the RFQ accelerator, and optimizing the structural parameters of the RFQ accelerator based on the second key factor to obtain second initial optimization parameters; Determining a third key factor that causes the RFQ accelerator to be too long, and optimizing the structural parameters of the RFQ accelerator based on the third key factor to obtain third initial optimization parameters; Determining a fourth key factor that causes low beam transmission efficiency, and optimizing the structural parameters of the RFQ accelerator based on the fourth key factor to obtain fourth initial optimization parameters; The fourth initial optimization parameter is determined as the first optimization parameter.

4. The design method of the RFQ accelerator for medical isotope production according to claim 3, characterized in that: Based on the target operating frequency range, determining a first key factor affecting the ignition coefficient of the RFQ accelerator, and optimizing the structural parameters of the RFQ accelerator based on the first key factor to obtain first initial optimization parameters, including: Based on the Kilpatrick criterion, determining a range of the Kilpatrick field corresponding to the target operating frequency range; Determining a maximum surface electric field range based on a preset value of the RFQ accelerator sparking coefficient and a range of the Kilpatrick field; Based on the relationship between the maximum surface electric field and the inter-electrode voltage of the RFQ accelerator, determining the inter-electrode voltage range corresponding to the maximum surface electric field range; The maximum surface electric field range and the inter-electrode voltage range are determined as the first initial optimization parameters.

5. The design method of the RFQ accelerator for medical isotope production according to claim 4, characterized in that: The determining of a second key factor causing insufficient lateral focusing of the RFQ accelerator, and optimizing the structural parameters of the RFQ accelerator based on the second key factor to obtain second initial optimization parameters, comprises: Determine the acceleration efficiency range based on formula (1) and formula (2); B=eλ 2 XV / γM0c 2 a 2 (1) X=1-AI0(ka)(2) Where A represents the acceleration efficiency; B represents the lateral focusing strength; X represents the lateral focusing factor; a represents the minimum aperture; V represents the inter-electrode voltage; λ represents the wavelength; β represents the particle velocity; M0 represents the particle rest mass; c represents the speed of light; a represents the minimum aperture of RFQ; I0 represents the zero-order Bessel function; L represents the unit length; The acceleration efficiency range is determined as a second initial optimization parameter.

6. The design method of the RFQ accelerator for medical isotope production according to claim 4, characterized in that: Determining a third key factor that causes the RFQ accelerator to be too long, and optimizing the structural parameters of the RFQ accelerator based on the third key factor to obtain third initial optimization parameters, including: Based on the preset values ​​of field leveling adjustment, beam transmission efficiency, and sparking coefficient, a beam dynamics simulation calculation is performed on the RFQ accelerator to obtain a length range of the RFQ accelerator; Based on the length range and the inter-electrode voltage range, determining an optimal length corresponding to an optimal inter-electrode voltage in the inter-electrode voltage range; The optimal length is determined as a third initial optimization parameter.

7. The design method of the RFQ accelerator for medical isotope production according to any one of claims 1 to 6, characterized in that: Based on the optimized dynamic design scheme, the structural parameters of the RFQ accelerator are designed at high frequency to determine the second optimized parameters, including: Comparing the power losses of RFQ accelerators with different preset structures, and determining the preset structure with the best power as the initial structure of the RFQ accelerator; Performing field-level tuning design on the initial structure to obtain a target structure of the RFQ accelerator; The target structure is determined as a second optimization parameter.

8. The design method of an RFQ accelerator for medical isotope production according to any one of claims 1 to 6, characterized in that: The step of optimizing the structural parameters of the cooling channel in the RFQ accelerator based on the high-frequency design solution to obtain third optimized parameters includes: Perform high-frequency simulation calculations on the RFQ accelerator to determine the main heating locations of the RFQ accelerator cavity; Based on the main parts, under the premise of ensuring the mechanical strength and stability of the RFQ accelerator, the cooling channel structural parameters in the RFQ accelerator cavity are designed, and the cooling channel structural parameters are determined as the third optimization parameters.

9. An ultra-high frequency room temperature linear accelerator system for the production of medical isotopes, characterized in that: include: An alpha ion source, used to generate an alpha beam with a high peak current, wherein the energy of the alpha beam is 10-20 keV and the current intensity of the alpha beam is 10-15 emA; An RFQ accelerator is connected to the α ion source through a low-energy transmission line, the RFQ accelerator is used to focus, bunch and accelerate the α beam, the frequency of the RFQ accelerator is 700-850 MHz, and the α beam energy at the outlet of the RFQ accelerator is 6-8 MeV; A drift tube linear accelerator is connected to the RFQ accelerator, the frequency of the drift tube linear accelerator is 700-850 MHz, and the drift tube linear accelerator accelerates the alpha beam with high peak current intensity output by the RFQ accelerator.

10. The ultra-high frequency room temperature linear accelerator system for the production of medical isotopes according to claim 9, characterized in that: The RFQ accelerator and the drift tube linear accelerator operate at a high duty cycle of 1%-2%, with an average beam intensity of 100-200 eμA. The RFQ accelerator adopts a quadrilateral four-wing structure, and the drift tube linear accelerator adopts a cross-type drift tube structure.

Citation Information

Patent Citations

  • Ultrahigh frequency linear accelerator for medical isotope production and parameter design method

    CN117580239A

  • Magneto-optic device display

    KR1020070023662A