Mild moisturizing cosmetic and preparation method thereof

Abstract

The invention discloses a mild moisturizing cosmetic and a preparation method thereof, and relates to the technical field of cosmetics. The preparation method comprises the following steps: firstly, extracting effective factors from oat for modification, and combining aldehyde-terminated beta-glucan with amino groups of lysine in the components to generate Schiff base, so that a synergistic mild antibacterial effect is achieved; lysine locks skin moisture and prevents moisture loss. Secondly, squalane is used as a carrier to load a natural antioxidant vitamin E, so that free radicals can be eliminated, oxidative damage can be reduced, skin aging can be delayed, the problem of dissolution of vitamin E in cosmetics can be solved, and meanwhile, the storage stability can be ensured; glycerin monostearate is combined with squalane to prepare a squalyl nano-lipid carrier, the squalyl nano-lipid carrier is cross-linked with flavonoid compounds in the oat extract through chemical bonds, and the squalyl nano-lipid carrier and the flavonoid compounds cooperate with antioxidation to effectively protect skin from being damaged by factors such as environmental pollution and ultraviolet rays, so that the skin is kept healthy and young. The prepared cosmetic has the effects of moisturizing, resisting bacteria and resisting bacteria.

Description

Technical Field

[0001] The invention relates to the technical field of cosmetics, in particular to a mild moisturizing cosmetic and a preparation method thereof. Background Art

[0002] With the acceleration of modern life and the aggravation of environmental pollution, the skin is facing more and more pressure and challenges. Problems such as dryness, sensitivity, and inflammation are becoming increasingly prominent, and consumers' demand for skin care products is gradually leaning towards mild moisturizing, anti-oxidation, and antibacterial effects. Mild moisturizing cosmetics can not only effectively lock in moisture and keep the skin moisturized, but also help the skin resist external stimuli and reduce inflammatory reactions by adding natural plant extracts, antioxidant ingredients, and antibacterial ingredients.

[0003] Therefore, relying solely on moisturizing can no longer effectively solve these problems. Antioxidant ingredients, such as vitamin C, vitamin E, and polyphenols, can neutralize free radicals, reduce oxidative damage, and delay skin aging. Antibacterial ingredients, such as plant extracts, ceramides, and dipotassium glycyrrhizinate, can soothe skin inflammation, repair damaged skin barriers, and relieve sensitive discomfort. The clever combination of moisturizing, anti-oxidation, and antibacterial effects is an important trend in modern cosmetic research and development. This multi-effect formula can not only provide the skin with sufficient moisture, but also effectively resist external aggression, repair damaged skin, and fundamentally improve the skin condition. However, how to choose the right ingredients and ensure their mildness to avoid irritating sensitive skin is a challenge faced during the research and development process. Summary of the invention

[0004] The object of the present invention is to provide a mild moisturizing cosmetic and a preparation method thereof, so as to solve the problems existing in the prior art.

[0005] In order to solve the above technical problems, the present invention provides the following technical solutions: a mild moisturizing cosmetic, wherein the skin care product is divided into two main components: a water-locking antibacterial component and a skin care anti-aging component.

[0006] Furthermore, the water-locking antibacterial ingredient is prepared by extracting effective factors from oats, modifying the effective factors, and then adding them into cosmetics to combine with lysine.

[0007] Furthermore, the skin care and anti-aging ingredient is prepared by squalane nano-lipid carrier loaded with vitamin E.

[0008] Furthermore, a method for preparing a mild moisturizing cosmetic comprises the following preparation steps: (1) Adding dried oat malt to deionized water, with a solid-liquid ratio of 1:10-20; adjusting the pH value to 10, stirring and heating at 120 rpm to 60-80°C for 60-120 min; stopping heating after the reaction, cooling the water to 50°C, centrifuging at 8000 rpm for 10 min, and taking the supernatant; adjusting the pH value of the supernatant to 5 with citric acid, adding amylase, stirring and reacting at 60-80°C for 40-80 min, then filtering with diatomaceous earth, keeping the temperature at 95°C for 30 min, and cooling to 5 in a water bath. 0°C, filtering out the solid to obtain an oat extract; dissolving the oat extract in deionized water at room temperature at a solid-liquid ratio of 1:8, then placing it in an ice water bath and adding sodium periodate to obtain a mixed solution, wherein the molar ratio of the oat extract to the sodium periodate is 2:1-3, and stirring the mixed solution at room temperature and in the dark for 2-6 hours at a stirring speed of 120 rpm; dialyzing the stirred solution in deionized water with a regenerated cellulose dialysis bag for 2-4 days, changing the deionized water every 3-6 hours during the dialysis process, and freeze-drying after the dialysis is completed to obtain a modified oat extract; (2) Place squalane, glyceryl monostearate and vitamin E in a beaker, heat them in a heat-collecting thermostatic heater at 60-80°C for 5-15 minutes until they are molten, and keep them warm for 2-5 hours to prepare an oil phase; then take deionized water and emulsifier Tween 20 in another beaker, the mass ratio of deionized water to emulsifier is 100:3, place it in a heat-collecting thermostatic heater and preheat it to 45°C, and use a rotary stirrer to stir at a speed of 300-600rpm for 15 minutes to disperse evenly; then move it to a desktop closed resistance furnace and heat it at 70°C for 5 minutes, keep it warm for 2-5 hours to prepare an aqueous phase; quickly add the aqueous phase to the oil phase, use a homogenizer to homogenize at a speed of 8000-12000rpm for 5 minutes to form colostrum, then move it to a CNC ultrasonic cleaner and perform ultrasonic dispersion for 20 minutes. After it is cooled to room temperature, it is a squalane nanolipid carrier; (3) Add 3-6 g of squalane nanolipid carrier, 1 g of stearic acid, 0.5-2.5 g of jojoba oil, 5-10 g of modified oat extract, 5-7 g of glycerol, 1-4.2 g of lysine, 0.3-0.5 g of hydroxyethyl cellulose, 0.5-1.5 g of surfactant and 50 g of water, and stir at 60 rpm for 20 min; then place the container on an electric stove and heat it at 50-70 ° C for 30 min. During the heating process, stir continuously and add water twice; after the reaction is completed, cool to 60 ° C, add 0.5-2.5 g of grape seed extract, stir evenly at 120 rpm for 20 min, and cool to room temperature to obtain a mild moisturizing cosmetic.

[0009] Furthermore, in step (1), the mass of amylase is 0.01% of the mass of the supernatant.

[0010] Furthermore, the molecular weight cut-off of the dialysis bag in step (1) is 400 Da.

[0011] Furthermore, in step (2), the mass ratio of squalane, glyceryl monostearate and vitamin E is 1:0.5-2:0.2-0.5.

[0012] Furthermore, the power of ultrasonic dispersion in step (2) is 300W.

[0013] Furthermore, the surfactant in step (3) is cocamidopropyl betaine.

[0014] Furthermore, in the step (3), water is added twice, with 2 g of water added each time.

[0015] Compared with the prior art, the beneficial effects achieved by the present invention are: The present invention uses modified oat extract and squalane nano lipid carrier as main effective ingredients to prepare cosmetics to achieve moisturizing, antibacterial and antimicrobial effects.

[0016] Firstly, the water-locking antibacterial ingredient is prepared by extracting effective factors from oats, modifying them, and then adding them into cosmetics in combination with lysine. Oat extract has excellent anti-aging effects, can smooth fine wrinkles, and improve skin texture. The aldehyde-terminated β-glucan combines with the amino group of lysine in the ingredient to form a Schiff base. On the basis of the anti-inflammatory effect of β-glucan itself, the Schiff base has a synergistic and mild antibacterial effect, which is suitable for sensitive skin. Lysine, as a natural moisturizing factor, has a strong water absorption capacity, can firmly lock in skin moisture and prevent water loss, thereby achieving a deep moisturizing effect. Secondly, the skin care and anti-aging ingredient is a squalane-based nanolipid carrier; squalane, as a natural skin lipid, has good skin affinity, can quickly penetrate into the deep layer of the skin, form a protective film, prevent water evaporation, moisturize the skin, and make it soft and smooth; the present invention uses squalane as a carrier and loads the natural antioxidant vitamin E, which can remove free radicals, reduce oxidative damage, and delay skin aging, solving the solubility problem of vitamin E in cosmetics while ensuring storage stability; squalane-based nanolipid carriers are prepared by combining monostearate with squalane, which is cross-linked with flavonoids in oat extract through chemical bonds, and synergistic antioxidant effects effectively protect the skin from environmental pollution, ultraviolet rays and other factors, keeping the skin healthy and young; the combination of the two can provide a lasting moisturizing effect for the skin, and in addition, it also has antibacterial and antimicrobial effects. DETAILED DESCRIPTION

[0017] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0018] In order to more clearly illustrate the method provided by the present invention, the following examples are used to describe in detail the test methods of various indicators of a mild moisturizing cosmetic prepared in the following examples as follows: Moisturizing: 10 healthy volunteers without skin diseases were selected for testing. The testing method is as follows: ① Determine 4 test areas on the left and right forearms, with an area of ​​4cm×4cm, and test the blank value of each area. ② Apply the sample to the test area at a dosage of 2mg / cm 2 ③ Test 60 min and 120 min after use, test 5 points in each area and take the average value. Evaluation formula for moisturizing effect evaluation: relative moisturizing rate / %=(P sample t=x- P blank) / (P standard t=x- P blank)×100; P sample t=x—the conductivity of the product after a certain period of use; P blank—the conductivity of the uncoated sample; P standard t=x—the conductivity of the reference after a certain period of use.

[0019] Antibacterial activity: Wash the 24-hour slant culture of the test bacteria (Staphylococcus aureus, Streptococcus, Escherichia coli) with PBS and prepare a bacterial suspension (the required concentration is: drop 100 μL on the control sample or in 5 ml of sample solution, and the number of recovered bacteria is 1 104 -9 104 cfu / ml). Take the samples of the embodiment and comparative example to prepare 10% sample aqueous solution and reference substance (deionized water) 5ml each, 4 tubes each, take the above bacterial suspension, add 100μL to each sample and reference substance respectively, and mix evenly. Start timing, act for 1d, use sterile tweezers to take samples (0.5mL) respectively and put them into test tubes containing 5mL PBS, mix thoroughly, make appropriate dilutions, then take 2-3 dilutions, take 0.5mL respectively, put them in two plates, pour 15mL of nutrient agar medium cooled to 40-45℃, rotate the plate to make it fully uniform, turn the plate over after the agar solidifies, and culture at 35℃±2℃ for 48h to count the viable colonies. Calculate the antibacterial rate: X=(AB) / A×100%.

[0020] Antioxidation: First add 9mmol / LFeSO4, 9mmoL / L ethanol salicylic acid, then add appropriate amount of deionized water, and finally add 8.8mmol / LH2O2 to the colorimetric tube and shake well. Heat in a 37℃ water bath for 15min and then take out to measure its absorbance A0. When measuring A0, the reference solution is a system without hydrogen peroxide. According to the above method, the absorbance AX and AX0 are measured. When measuring AX and AX0, the reference solution is deionized water. Calculation formula: Hydroxyl free radical scavenging rate (%) = A0-(AX-AX0) / A0*100%, where A0 is the absorbance value of the blank control; AX is the absorbance value of the sample; AX0 is the background absorbance value of the solution without the color developer H2O2. Example 1

[0021] (1) Add dry oat malt to deionized water with a solid-liquid ratio of 1:10; adjust the pH value to 10, stir and heat at 120 rpm to 60°C for 60 minutes; stop heating after the reaction, cool to 50°C with water circulation, centrifuge at 8000 rpm for 10 minutes, and take the supernatant; adjust the pH value of the supernatant to 5 with citric acid, add 0.01% amylase by mass of the supernatant, stir and react at 60°C for 40 minutes, then filter with diatomaceous earth, keep at 95°C for 30 minutes, cool to 50°C in a water bath, and filter to take the solid; The oat extract is prepared by dissolving the oat extract in deionized water at a solid-liquid ratio of 1:8 at room temperature, and then placing the mixture in an ice water bath and adding sodium periodate to obtain a mixed solution, wherein the molar ratio of the oat extract to the sodium periodate is 2:1, and the mixed solution is stirred for reaction at room temperature and in the dark for 2 hours at a stirring speed of 120 rpm; the stirred solution is dialyzed in deionized water for 2 days using a regenerated cellulose dialysis bag, wherein the molecular weight cutoff of the dialysis bag is 400 Da, and the deionized water is replaced every 3 hours during the dialysis process, and after the dialysis is completed, the modified oat extract is freeze-dried; (2) Squalane, glyceryl monostearate, vitamin E Place in a beaker, the mass ratio of squalane, monostearate glyceryl, and vitamin E is 1:0.5:0.2, heat at 60°C in a thermal collector thermostatic heater for 5 minutes until it is molten, and keep warm for 2 hours to prepare an oil phase; then take deionized water and emulsifier Tween 20 in another beaker, the mass ratio of deionized water to emulsifier is 100:3, place in a thermal collector thermostatic heater and preheat to 45°C, and use a rotary stirrer to stir at a speed of 300rpm for 15 minutes to disperse evenly; then move to a desktop closed resistance furnace and heat at 70°C for 5 minutes, keep warm for 2 hours to prepare an aqueous phase; quickly add the aqueous phase to the oil phase, use a homogenizer to homogenize at a speed of 8000rpm for 5 minutes to form colostrum, then move to a CNC ultrasonic cleaner, perform ultrasonic dispersion at a power of 300W for 20 minutes, and after it is cooled to room temperature, it is a squalane nanolipid carrier; (3) 3 g of squalane nanolipid carrier, 1 g of stearic acid, 0.5 g of jojoba oil, 5 g of modified oat extract, 5 g of glycerin, 1 g of lysine, 0.3 g of hydroxyethyl cellulose, 0.5 g of cocamidopropyl betaine and 50 g of water were stirred at 60 rpm for 20 min; then the container was placed on an electric stove and heated at 50°C for 30 min. During the heating process, stirring was continued and 2 g of water was added twice; after the reaction was completed, the mixture was cooled to 60°C, 0.5 g of grape seed extract was added, and the mixture was stirred evenly at 120 rpm for 20 min. The mixture was cooled to room temperature to obtain a mild moisturizing cosmetic. Example 2

[0022] (1) Add dry oat malt to deionized water with a solid-liquid ratio of 1:15; adjust the pH value to 10, stir and heat at 120 rpm to 70°C for 90 minutes; stop heating after the reaction, cool the water to 50°C, centrifuge at 8000 rpm for 10 minutes, and take the supernatant; adjust the pH value of the supernatant to 5 with citric acid, add 0.01% amylase by mass of the supernatant, stir and react at 70°C for 60 minutes, then filter with diatomaceous earth, keep at 95°C for 30 minutes, cool to 50°C in a water bath, and filter to take the solid Prepare oat extract; dissolve the oat extract in deionized water at room temperature in a solid-liquid ratio of 1:8, then place it in an ice water bath and add sodium periodate to obtain a mixed solution, the molar ratio of the oat extract to the sodium periodate is 2:2, and stir the mixed solution at room temperature and in the dark for 4 hours at a stirring speed of 120 rpm; dialyze the stirred solution in deionized water for 3 days using a regenerated cellulose dialysis bag, the molecular weight cutoff of the dialysis bag is 400 Da, and the deionized water is replaced every 4.5 hours during the dialysis process. After the dialysis is completed, freeze-drying is performed to obtain a modified oat extract; (2) Squalane, glyceryl monostearate, vitamin E Place in a beaker, the mass ratio of squalane, monostearate glyceryl, and vitamin E is 1:1.25:0.35, heat at 70°C in a thermal collector thermostat heater for 10 minutes until molten, keep warm for 3.5 hours, and prepare an oil phase; then take deionized water and emulsifier Tween 20 in another beaker, the mass ratio of deionized water to emulsifier is 100:3, place in a thermal collector thermostat heater and preheat to 45°C, and use a rotary stirrer to stir at a speed of 450rpm for 15 minutes to disperse evenly; then move to a desktop closed resistance furnace and heat at 70°C for 5 minutes, keep warm for 3.5 hours to prepare a water phase; quickly add the water phase to the oil phase, use a homogenizer to homogenize at a speed of 10000rpm for 5 minutes to form colostrum, then move to a CNC ultrasonic cleaner, perform ultrasonic dispersion at a power of 300W for 20 minutes, and after it is cooled to room temperature, it is a squalane nanolipid carrier; (3) 4.5 g of squalane nanolipid carrier, 1 g of stearic acid, 1.5 g of jojoba oil, 7.5 g of modified oat extract, 6 g of glycerin, 2.6 g of lysine, 0.4 g of hydroxyethyl cellulose, 1 g of cocamidopropyl betaine and 50 g of water were stirred at 60 rpm for 20 min. The container was then placed on an electric stove and heated at 60°C for 30 min. During the heating process, the mixture was stirred continuously and 2 g of water was added twice. After the reaction was completed, the mixture was cooled to 60°C, 1.5 g of grape seed extract was added, and the mixture was stirred evenly at 120 rpm for 20 min. The mixture was cooled to room temperature to obtain a mild moisturizing cosmetic. Example 3

[0023] (1) Add deionized water to dry oat malt at a solid-liquid ratio of 1:20; adjust the pH value to 10, stir and heat at 120 rpm to 80°C for 120 min; stop heating after the reaction, cool to 50°C with water circulation, centrifuge at 8000 rpm for 10 min, and take the supernatant; adjust the pH value of the supernatant to 5 with citric acid, add 0.01% amylase by mass of the supernatant, stir and react at 80°C for 80 min, then filter with diatomaceous earth, keep at 95°C for 30 min, cool to 50°C in a water bath, and filter to take the solid; The oat extract is prepared by dissolving the oat extract in deionized water at a solid-liquid ratio of 1:8 at room temperature, and then placing the mixture in an ice water bath and adding sodium periodate to obtain a mixed solution, wherein the molar ratio of the oat extract to the sodium periodate is 2:3, and the mixed solution is stirred for reaction at room temperature and in the dark for 6 hours at a stirring speed of 120 rpm; the stirred solution is dialyzed in deionized water for 4 days using a regenerated cellulose dialysis bag, wherein the molecular weight cutoff of the dialysis bag is 400 Da, and the deionized water is replaced every 6 hours during the dialysis process, and after the dialysis is completed, the modified oat extract is freeze-dried; (2) Squalane, glyceryl monostearate, vitamin E Place in a beaker, the mass ratio of squalane, monostearate glyceryl, and vitamin E is 1:2:0.5, heat at 80°C in a thermal collector thermostat heater for 15 minutes until it is molten, and keep warm for 5 hours to prepare an oil phase; then take deionized water and emulsifier Tween 20 in another beaker, the mass ratio of deionized water to emulsifier is 100:3, place in a thermal collector thermostat heater and preheat to 45°C, and use a rotary stirrer to stir at a speed of 600rpm for 15 minutes to disperse evenly; then move to a desktop closed resistance furnace and heat at 70°C for 5 minutes, keep warm for 5 hours to prepare an aqueous phase; quickly add the aqueous phase to the oil phase, use a homogenizer to homogenize at a speed of 12000rpm for 5 minutes to form colostrum, and then move to a CNC ultrasonic cleaner, perform ultrasonic dispersion at a power of 300W for 20 minutes, and after it is cooled to room temperature, it is a squalane nanolipid carrier; (3) 6 g of squalane nanolipid carrier, 1 g of stearic acid, 2.5 g of jojoba oil, 10 g of modified oat extract, 7 g of glycerin, 4.2 g of lysine, 0.5 g of hydroxyethyl cellulose, 1.5 g of cocamidopropyl betaine and 50 g of water were stirred at 60 rpm for 20 min; then the container was placed on an electric stove and heated at 70°C for 30 min. During the heating process, stirring was continued and 2 g of water was added twice; after the reaction was completed, the mixture was cooled to 60°C, 2.5 g of grape seed extract was added, and the mixture was stirred evenly at 120 rpm for 20 min. The mixture was cooled to room temperature to obtain a mild moisturizing cosmetic.

[0024] Comparative Example 1 The difference between Comparative Example 1 and Example 2 is that step (1) is omitted, and step (3) is changed to: 4.5 g of squalane nanolipid carrier, 1 g of stearic acid, 1.5 g of jojoba oil, 6 g of glycerin, 2.6 g of lysine, 0.4 g of hydroxyethyl cellulose, 1 g of cocamidopropyl betaine and 50 g of water are stirred at 60 rpm for 20 min; then the container is placed on an electric stove and heated at 60° C. for 30 min. During the heating process, stirring is continued, and 2 g of water is added twice; after the reaction is completed, the mixture is cooled to 60° C., 1.5 g of grape seed extract is added, the mixture is stirred evenly at 120 rpm for 20 min, and the mixture is cooled to room temperature to obtain a mild moisturizing cosmetic; the remaining steps are the same as those of Example 2.

[0025] Comparative Example 2 The difference between Comparative Example 2 and Example 2 lies in the difference in steps (1) (3), whereby steps (1) (3) are modified as follows: (1) adding dry oat malt to deionized water with a solid-liquid ratio of 1:15; adjusting the pH value to 10, stirring and heating at a speed of 120 rpm to 70°C for 90 minutes; stopping heating after the reaction, cooling the mixture to 50°C by water circulation, centrifuging at a speed of 8000 rpm for 10 minutes, and taking the supernatant; adjusting the pH value of the supernatant to 5 with citric acid, adding 0.01% amylase by mass of the supernatant, stirring and reacting at 70°C for 60 minutes, and then filtering with diatomaceous earth, keeping the mixture at 95°C for 30 minutes, cooling the mixture to 50°C in a water bath, and filtering the solid to obtain an oat extract; (3) 4.5 g of squalane nanolipid carrier, 1 g of stearic acid, 1.5 g of jojoba oil, 7.5 g of oat extract, 6 g of glycerin, 2.6 g of lysine, 0.4 g of hydroxyethyl cellulose, 1 g of cocamidopropyl betaine and 50 g of water were stirred at 60 rpm for 20 min; then the container was placed on an electric stove and heated at 60° C. for 30 min. During the heating process, stirring was continued and 2 g of water was added twice; after the reaction was completed, the mixture was cooled to 60° C., 1.5 g of grape seed extract was added, and the mixture was stirred evenly at 120 rpm for 20 min. The mixture was cooled to room temperature to obtain a mild moisturizing cosmetic; the remaining steps were the same as those in Example 2.

[0026] Comparative Example 3 The difference between Comparative Example 3 and Example 2 is that step (3) is different. Step (3) is changed to: 4.5 g of squalane nanolipid carrier, 1 g of stearic acid, 1.5 g of jojoba oil, 7.5 g of modified oat extract, 6 g of glycerin, 0.4 g of hydroxyethyl cellulose, 1 g of cocamidopropyl betaine and 50 g of water are stirred at 60 rpm for 20 min; then the container is placed on an electric stove and heated at 60° C. for 30 min. During the heating process, stirring is continued and 2 g of water is added twice; after the reaction is completed, the mixture is cooled to 60° C., 1.5 g of grape seed extract is added, and the mixture is stirred evenly at 120 rpm for 20 min. The mixture is cooled to room temperature to obtain a mild moisturizing cosmetic; the remaining steps are the same as those of Example 2.

[0027] Comparative Example 4 The difference between Comparative Example 4 and Example 2 is that step (2) is different. Step (2) is changed to: squalane and glyceryl monostearate are placed in a beaker, the mass ratio of squalane to glyceryl monostearate is 1:1.25, and heated at 70°C in a thermal collector constant temperature heater for 10 minutes until they are in a molten state, and kept warm for 3.5 hours to prepare an oil phase; deionized water and emulsifier Tween 20 are taken in another beaker, the mass ratio of deionized water to emulsifier is 100:3, and placed in a thermal collector constant temperature heater and preheated to 45°C. At the same time, a rotary stirrer was used to stir at a speed of 450 rpm for 15 minutes to disperse evenly; then the mixture was moved to a desktop closed resistance furnace and heated at 70° C. for 5 minutes and kept warm for 3.5 hours to prepare an aqueous phase; the aqueous phase was quickly added to the oil phase, and a homogenizer was used to homogenize at a speed of 10,000 rpm for 5 minutes to form colostrum, and then the mixture was moved to a CNC ultrasonic cleaner and ultrasonically dispersed at a power of 300 W for 20 minutes. After it was cooled to room temperature, it was a squalane nanolipid carrier; the remaining steps were the same as in Example 2.

[0028] Comparative Example 5 The difference between Comparative Example 5 and Example 2 is that step (2) is omitted, and step (3) is changed to: 3.5 g of glyceryl monostearate, 1 g of vitamin E, 1 g of stearic acid, 1.5 g of jojoba oil, 7.5 g of modified oat extract, 6 g of glycerol, 2.6 g of lysine, 0.4 g of hydroxyethyl cellulose, 1 g of cocamidopropyl betaine and 50 g of water are stirred at 60 rpm for 20 min; then the container is placed on an electric stove and heated at 60° C. for 30 min. During the heating process, stirring is continued, and 2 g of water is added twice; after the reaction is completed, the mixture is cooled to 60° C., 1.5 g of grape seed extract is added, and the mixture is stirred evenly at 120 rpm for 20 min. The mixture is cooled to room temperature to obtain a mild moisturizing cosmetic; the remaining steps are the same as those of Example 2.

[0029] Effect example Table 1 below shows the performance analysis results of a mild moisturizing cosmetic using Examples 1 to 3 of the present invention and Comparative Examples 1 to 5.

[0030] Table 1

[0031] From the comparison of the experimental data of the antioxidant properties of the embodiment and the comparative example, it can be found that the present invention extracts effective factors from oats, modifies them and then adds them into cosmetics to combine with lysine; oat extract has excellent anti-aging effects, can smooth fine wrinkles, and improve skin texture. The present invention uses squalane as a carrier to load the natural antioxidant vitamin E, which can remove free radicals, reduce oxidative damage, delay skin aging, solve the dissolution problem of vitamin E in cosmetics, and ensure storage stability. The present invention uses glyceryl monostearate in combination with squalane to prepare a squalane-based nanolipid carrier, which is cross-linked with the flavonoids in the oat extract by chemical bonds, and synergistic antioxidants effectively protect the skin from environmental pollution, ultraviolet rays and other factors, and keep the skin healthy and young. From the comparison of the experimental data of the antibacterial property of the embodiment and the comparative example, it can be found that the aldehyde-terminated β-glucan of the present invention combines with the amino group of lysine in the ingredient to form a Schiff base. On the basis of the antibacterial property of the β-glucan itself, the Schiff base plays a synergistic and mild antibacterial effect, which is suitable for sensitive skin; from the comparison of the experimental data of the moisturizing property of the embodiment and the comparative example, it can be found that the lysine of the present invention, as a natural moisturizing factor, has a strong water absorption capacity, can firmly lock the moisture of the skin, prevent water loss, and thus achieve the effect of deep moisturizing. Secondly, the skin care and anti-aging ingredient of the present invention is a squalane nanolipid carrier; squalane, as a natural skin lipid, has good skin affinity, can quickly penetrate into the deep layer of the skin, form a protective film, prevent water evaporation, moisturize the skin, and make it soft and smooth.

[0032] It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above and that the invention can be implemented in other specific forms without departing from the spirit or essential features of the invention. Therefore, the embodiments should be considered in all respects as exemplary and non-limiting, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations within the meaning and scope of the equivalent elements of the claims be included in the invention. Any marking in a claim should not be considered as limiting the claim to which it relates.

Claims

1. A mild moisturizing cosmetic, characterized in that: The skin care products are divided into two main components: water-locking antibacterial components and skin care anti-aging components.

2. A mild moisturizing cosmetic according to claim 1, characterized in that: The water-locking antibacterial ingredient is prepared by extracting effective factors from oats, modifying the effective factors, and then adding them into cosmetics to combine with lysine.

3. A mild moisturizing cosmetic according to claim 1, characterized in that: The skin care and anti-aging ingredient is prepared by using squalane nano lipid carrier loaded with vitamin E.

4. A method for preparing a mild moisturizing cosmetic, characterized in that: The method comprises the following preparation steps: (1) Adding dried oat malt to deionized water, with a solid-liquid ratio of 1:10-20; adjusting the pH value to 10, stirring and heating at 120 rpm to 60-80°C for 60-120 min; stopping heating after the reaction, cooling the water to 50°C, centrifuging at 8000 rpm for 10 min, and taking the supernatant; adjusting the pH value of the supernatant to 5 with citric acid, adding amylase, stirring and reacting at 60-80°C for 40-80 min, then filtering with diatomaceous earth, keeping the temperature at 95°C for 30 min, and cooling to 5 in a water bath. 0°C, filtering out the solid to obtain an oat extract; dissolving the oat extract in deionized water at room temperature at a solid-liquid ratio of 1:8, then placing it in an ice water bath and adding sodium periodate to obtain a mixed solution, wherein the molar ratio of the oat extract to the sodium periodate is 2:1-3, and stirring the mixed solution at room temperature and in the dark for 2-6 hours at a stirring speed of 120 rpm; dialyzing the stirred solution in deionized water with a regenerated cellulose dialysis bag for 2-4 days, changing the deionized water every 3-6 hours during the dialysis process, and freeze-drying after the dialysis is completed to obtain a modified oat extract; (2) Place squalane, glyceryl monostearate and vitamin E in a beaker, heat them in a heat-collecting thermostatic heater at 60-80°C for 5-15 minutes until they are molten, and keep them warm for 2-5 hours to prepare an oil phase; then take deionized water and emulsifier Tween 20 in another beaker, the mass ratio of deionized water to emulsifier is 100:3, place it in a heat-collecting thermostatic heater and preheat it to 45°C, and use a rotary stirrer to stir at a speed of 300-600rpm for 15 minutes to disperse evenly; then move it to a desktop closed resistance furnace and heat it at 70°C for 5 minutes, keep it warm for 2-5 hours to prepare an aqueous phase; quickly add the aqueous phase to the oil phase, use a homogenizer to homogenize at a speed of 8000-12000rpm for 5 minutes to form colostrum, then move it to a CNC ultrasonic cleaner and perform ultrasonic dispersion for 20 minutes. After it is cooled to room temperature, it is a squalane nanolipid carrier; (3) Add 3-6 g of squalane nanolipid carrier, 1 g of stearic acid, 0.5-2.5 g of jojoba oil, 5-10 g of modified oat extract, 5-7 g of glycerol, 1-4.2 g of lysine, 0.3-0.5 g of hydroxyethyl cellulose, 0.5-1.5 g of surfactant and 50 g of water, and stir at 60 rpm for 20 min; then place the container on an electric stove and heat it at 50-70 ° C for 30 min. During the heating process, stir continuously and add water twice; after the reaction is completed, cool to 60 ° C, add 0.5-2.5 g of grape seed extract, stir evenly at 120 rpm for 20 min, and cool to room temperature to obtain a mild moisturizing cosmetic.

5. The method for preparing a mild moisturizing cosmetic according to claim 4, characterized in that: The mass of amylase in step (1) is 0.01% of the mass of the supernatant.

6. The method for preparing a mild moisturizing cosmetic according to claim 4, characterized in that: The molecular weight cut-off of the dialysis bag in step (1) is 400 Da.

7. The method for preparing a mild moisturizing cosmetic according to claim 4, characterized in that: In the step (2), the mass ratio of squalane, glyceryl monostearate and vitamin E is 1:0.5-2:0.2-0.

5.

8. The method for preparing a mild moisturizing cosmetic according to claim 4, characterized in that: The power of ultrasonic dispersion in step (2) is 300W.

9. The method for preparing a mild moisturizing cosmetic according to claim 4, characterized in that: The surfactant in step (3) is cocamidopropyl betaine.

10. The method for preparing a mild moisturizing cosmetic according to claim 4, characterized in that: In the step (3), water is added twice, with 2 g of water added each time.

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