Preparation prepared from multiple Chinese herbal medicines and used for protecting liver injury, repairing and nourishing liver

Abstract

The invention discloses a preparation prepared from various Chinese herbal medicines and used for protecting liver injury, repairing and nourishing liver, which belongs to the technical field of traditional Chinese medicine preparations and comprises a liver-clearing and gallbladder-benefiting combination, a liver-soothing and qi-promoting combination, a liver-clearing and eyesight-improving combination, a liver-yin-nourishing combination, main materials and auxiliary materials. The traditional Chinese medicine composition is characterized by comprising the following raw materials in parts by weight: 20-30 parts of a liver-clearing and gallbladder-benefiting composition, 10-20 parts of a liver-soothing and qi-promoting composition, 10-20 parts of a liver-clearing and eyesight-improving composition, 20-30 parts of a liver-yin-nourishing composition, 20-30 parts of a main material and 30-40 parts of an auxiliary material, the liver-clearing and gallbladder-benefiting composition is a mixture of oriental wormwood, radix bupleuri and cape jasmine, and the mixing ratio of the mixture is 3: 1: 1. The production place of the oriental wormwood is Shanxi province or Hebei province, the production place of the radix bupleuri and the fructus gardeniae is Sichuan province, and the liver-soothing and qi-promoting combination is a mixture of honeysuckle and fingered citron. The preparation for protecting the liver injury, repairing and nourishing the liver, which is prepared from various Chinese herbal medicines, not only can treat the liver injury from multiple directions, but also can repair and nourish the liver.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine preparations, in particular to a preparation made from a variety of Chinese herbal medicines for protecting liver damage, repairing and nourishing the liver. Background Art

[0002] The liver contains a rich enzyme system and is an important organ for biological transformation. When the liver is damaged, it has a huge impact on the body, so there are many drugs that protect the liver, repair and nourish the liver. However, traditional preparations have a single function and do not treat the liver from multiple aspects, so the effect is weak.

[0003] After searching, the Chinese patent document (authorization announcement number CN102233061B) is a Chinese medicine compound preparation for treating liver damage and its preparation process. The preparation is made of the following raw materials in weight ratio: 10-20 parts of Artemisia capillaris, 10-20 parts of green peel, 5-15 parts of wolfberry, 5-15 parts of raw earth, 5-15 parts of Codonopsis pilosula, 5-15 parts of Ligustrum lucidum, and 5-15 parts of Schisandra chinensis. Artemisia capillaris can relieve dampness and soothe the liver and gallbladder, and is the main medicine for urination; Green peel is used to break qi and relieve liver depression as the minister medicine; Lycium barbarum and Ligustrum lucidum are used to nourish the liver and kidney. All the medicines play the effects of promoting gallbladder and relieving jaundice, nourishing the liver and kidney, and have significant effects on liver damage, jaundice, and rib pain caused by liver qi discomfort caused by anti-tuberculosis drugs. The Chinese medicine compound preparation for treating liver damage made by the present invention has simple process control, high bioavailability, good drug efficacy, fast efficacy, and low cost. However, the function of the preparation is relatively single, and the liver is not treated from many aspects, so the effect is weak. Summary of the invention

[0004] The object of the present invention is to provide a preparation made of a variety of Chinese herbal medicines for protecting liver damage, repairing and nourishing the liver, so as to solve the problems raised in the background technology.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical scheme: a preparation for protecting liver damage, repairing and nourishing the liver made of multiple Chinese herbal medicines, including a liver-clearing and gallbladder-invigorating combination, a liver-soothing and qi-promoting combination, a liver-clearing and eyesight-improving combination, a liver-tonifying and yin-replenishing combination, main ingredients and auxiliary ingredients, characterized in that the weight and mass proportions of each raw material are: 20-30 parts of the liver-clearing and gallbladder-invigorating combination, 10-20 parts of the liver-soothing and qi-promoting combination, 10-20 parts of the liver-clearing and eyesight-improving combination, 20-30 parts of the liver-tonifying and yin-replenishing combination, 20-30 parts of the main ingredients and 30-40 parts of the auxiliary ingredients.

[0006] As a preferred embodiment, the liver-clearing and gallbladder-promoting combination is set as a mixture of Artemisia capillaris, Bupleurum chinense and Gardenia jasminoides, and the mixing ratio of the mixture is set to 3:1:1.

[0007] As a preferred embodiment, the origin of the Artemisia capillaris is set to Shanxi Province or Hebei Province, and the origin of Bupleurum and Gardenia jasminoides is set to Sichuan Province.

[0008] As a preferred embodiment, the liver-soothing and qi-promoting combination is set as a mixture of honeysuckle and bergamot, and the mixing ratio of the mixture is set to 3:1.

[0009] As a preferred embodiment, the origin of the honeysuckle is set to the Tibet Autonomous Region or Sichuan Province, and the origin of the bergamot is set to Guangdong Province.

[0010] As a preferred embodiment, the liver-clearing and eyesight-improving combination is set as a mixture of chrysanthemum, semen cassiae, mulberry leaves and burdock seeds, and the mixing ratio of the mixture is set to 3:1:3:1, and the chrysanthemum is set to be chrysanthemum from Zhejiang Province.

[0011] As a preferred embodiment, the liver yin nourishing combination is set as a mixture of Ophiopogon japonicus, Rehmannia glutinosa, Polygonatum sibiricum and Lycium barbarum, and the mixing ratio of the mixture is set to 3:1:1:5.

[0012] As a preferred embodiment, the main ingredient is set as a mixture of Hovenia dulcis, Poria cocos, Alisma orientalis and dried tangerine peel, and the mixture is mixed in equal proportions. The auxiliary material is set as a mixture of white peony root, wolfberry fruit and Salvia miltiorrhiza, and the mixing ratio of the mixture is set to 3:2:1.

[0013] A method for preparing a preparation for protecting liver damage, repairing and nourishing the liver made from a variety of Chinese herbal medicines, comprising the following steps:

[0014] Step 1, weigh the Chinese medicine according to the above weight;

[0015] Step 2: Put the weighed Chinese medicine into water for washing;

[0016] Step 3: Put the cleaned raw materials into a medicine cooker with water to cook the medicine;

[0017] Step 4: After the medicine is cooked, the medicine is obtained, and then it is naturally cooled and then packaged in a quantitative manner.

[0018] As a preferred embodiment, the cleaning time of step two is set to three minutes, and the boiling time of step three is set to 40-60 minutes.

[0019] Compared with the prior art, the technical effects and advantages of the present invention are as follows:

[0020] This preparation made of multiple Chinese herbal medicines for protecting liver damage, repairing and nourishing the liver can treat liver damage from multiple directions and protect the liver, thanks to the combination of liver-clearing and gallbladder-promoting, liver-soothing and qi-promoting, liver-clearing and eyesight-improving, and the coordination of the main ingredients. Compared with traditional single-direction treatment, it has better effects.

[0021] This preparation made of multiple Chinese herbal medicines for protecting liver damage, repairing and nourishing the liver can repair and nourish the liver thanks to the combination of nourishing liver yin and auxiliary materials. Nourishing liver yin essentially repairs the liver. The auxiliary materials are white peony root, wolfberry, and salvia miltiorrhiza, which can nourish the body and comprehensively nourish the body.

[0022] This preparation, which is made from a variety of Chinese herbal medicines for protecting liver damage, repairing and nourishing the liver, can not only treat liver damage from multiple directions, but also repair and nourish the liver. DETAILED DESCRIPTION

[0023] In the following description, a large number of specific details are provided to provide a more thorough understanding of the present invention. However, it is apparent to those skilled in the art that the present invention can be implemented without one or more of these details. In other examples, in order to avoid confusion with the present invention, some technical features well known in the art are not described.

[0024] The connection method can be bonding, welding, bolt connection, etc., depending on actual needs.

[0025] Embodiment 1

[0026] This embodiment includes a liver-clearing and bile-promoting combination, a liver-soothing and qi-promoting combination, a liver-clearing and eyesight-improving combination, a liver-tonifying and yin-tonifying combination, main ingredients and auxiliary ingredients, and is characterized in that the weight and mass proportions of each raw material are as follows: 20 parts of the liver-clearing and bile-promoting combination, 10 parts of the liver-soothing and qi-promoting combination, 10 parts of the liver-clearing and eyesight-improving combination, 20 parts of the liver-tonifying and yin-tonifying combination, 20 parts of the main ingredient and 30 parts of the auxiliary ingredient.

[0027] The liver-clearing and gallbladder-promoting combination is set as a mixture of Artemisia capillaris, Bupleurum chinense and Gardenia jasminoides. Other more cost-effective Chinese medicines can also be designed, and the mixing ratio of the mixture is set to 3:1:1. The origin of Artemisia capillaris is set to Shanxi Province or Hebei Province, and the origin of Bupleurum chinense and Gardenia jasminoides is set to Sichuan Province.

[0028] The combination for soothing the liver and promoting qi is set as a mixture of honeysuckle and bergamot. Other Chinese medicines with higher cost performance can also be designed, and the mixing ratio of the mixture is set to 3:1. The origin of honeysuckle is set to Tibet Autonomous Region or Sichuan Province, and the origin of bergamot is set to Guangdong Province.

[0029] The liver-clearing and eyesight-improving combination is set as a mixture of chrysanthemum, semen cassiae, mulberry leaves and burdock seeds, and the mixing ratio of the mixture is set to 3:1:3:1. The chrysanthemum is set to Hangzhou chrysanthemum from Zhejiang Province. The chrysanthemum can also be set to other chrysanthemums that are easily available, such as Chuju and the like.

[0030] The liver yin nourishing combination is set as a mixture of Ophiopogon japonicus, Rehmannia glutinosa, Polygonatum sibiricum and Lycium barbarum, and the mixing ratio of the mixture is set to 3:1:1:5.

[0031] The auxiliary materials are set as a mixture of white peony root, wolfberry and salvia miltiorrhiza. Salvia miltiorrhiza has been irradiated. Salvia miltiorrhiza can also be replaced with targeted ginseng substances such as Codonopsis pilosula, and the mixing ratio of the mixture is set to 3:2:1.

[0032] A method for preparing a preparation for protecting liver damage, repairing and nourishing the liver made from a variety of Chinese herbal medicines, comprising the following steps:

[0033] Step 1, weigh the Chinese medicine according to the above weight;

[0034] Step 2: Put the weighed Chinese medicine into water for washing, and set the washing time to three minutes;

[0035] Step 3: Put the cleaned raw materials into a water-boiler and boil them. Set the boiling time to 40 minutes.

[0036] Step 4: After the medicine is cooked, the medicine is obtained, and then it is naturally cooled and then packaged in a quantitative manner.

[0037] Embodiment 2

[0038] This embodiment includes a liver-clearing and bile-promoting combination, a liver-soothing and qi-promoting combination, a liver-clearing and eyesight-improving combination, a liver-tonifying and yin-tonifying combination, main ingredients and auxiliary ingredients, and is characterized in that the weight and mass proportions of each raw material are as follows: 30 parts of the liver-clearing and bile-promoting combination, 20 parts of the liver-soothing and qi-promoting combination, 20 parts of the liver-clearing and eyesight-improving combination, 30 parts of the liver-tonifying and yin-tonifying combination, 30 parts of the main ingredient and 40 parts of the auxiliary ingredient.

[0039] The liver-clearing and gallbladder-promoting combination is set as a mixture of Artemisia capillaris, Bupleurum chinense and Gardenia jasminoides. Other more cost-effective Chinese medicines can also be designed, and the mixing ratio of the mixture is set to 3:1:1. The origin of Artemisia capillaris is set to Shanxi Province or Hebei Province, and the origin of Bupleurum chinense and Gardenia jasminoides is set to Sichuan Province.

[0040] The combination for soothing the liver and promoting qi is set as a mixture of honeysuckle and bergamot. Other Chinese medicines with higher cost performance can also be designed, and the mixing ratio of the mixture is set to 3:1. The origin of honeysuckle is set to Tibet Autonomous Region or Sichuan Province, and the origin of bergamot is set to Guangdong Province.

[0041] The liver-clearing and eyesight-improving combination is set as a mixture of chrysanthemum, semen cassiae, mulberry leaves and burdock seeds, and the mixing ratio of the mixture is set to 3:1:3:1. The chrysanthemum is set to Hangzhou chrysanthemum from Zhejiang Province. The chrysanthemum can also be set to other chrysanthemums that are easily available, such as Chuju and the like.

[0042] The liver yin nourishing combination is set as a mixture of Ophiopogon japonicus, Rehmannia glutinosa, Polygonatum sibiricum and Lycium barbarum, and the mixing ratio of the mixture is set to 3:1:1:5.

[0043] The auxiliary materials are set as a mixture of white peony root, wolfberry and salvia miltiorrhiza. Salvia miltiorrhiza has been irradiated. Salvia miltiorrhiza can also be replaced with targeted ginseng substances such as Codonopsis pilosula, and the mixing ratio of the mixture is set to 3:2:1.

[0044] A method for preparing a preparation for protecting liver damage, repairing and nourishing the liver made from a variety of Chinese herbal medicines, comprising the following steps:

[0045] Step 1, weigh the Chinese medicine according to the above weight;

[0046] Step 2: Put the weighed Chinese medicine into water for washing, and set the washing time to three minutes;

[0047] Step 3: Put the cleaned raw materials into a medicine cooker with water and cook them for 60 minutes;

[0048] Step 4: After the medicine is cooked, the medicine is obtained, and then it is naturally cooled and then packaged in a quantitative manner.

[0049] Embodiment 3

[0050] This embodiment includes a liver-clearing and bile-promoting combination, a liver-soothing and qi-promoting combination, a liver-clearing and eyesight-improving combination, a liver-tonifying and yin-tonifying combination, main ingredients and auxiliary ingredients, and is characterized in that the weight and mass proportions of each raw material are as follows: 25 parts of the liver-clearing and bile-promoting combination, 15 parts of the liver-soothing and qi-promoting combination, 15 parts of the liver-clearing and eyesight-improving combination, 25 parts of the liver-tonifying and yin-tonifying combination, 25 parts of the main ingredient and 35 parts of the auxiliary ingredient.

[0051] The liver-clearing and gallbladder-promoting combination is set as a mixture of Artemisia capillaris, Bupleurum chinense and Gardenia jasminoides. Other more cost-effective Chinese medicines can also be designed, and the mixing ratio of the mixture is set to 3:1:1. The origin of Artemisia capillaris is set to Shanxi Province or Hebei Province, and the origin of Bupleurum chinense and Gardenia jasminoides is set to Sichuan Province.

[0052] The combination for soothing the liver and promoting qi is set as a mixture of honeysuckle and bergamot. Other Chinese medicines with higher cost performance can also be designed, and the mixing ratio of the mixture is set to 3:1. The origin of honeysuckle is set to Tibet Autonomous Region or Sichuan Province, and the origin of bergamot is set to Guangdong Province.

[0053] The liver-clearing and eyesight-improving combination is set as a mixture of chrysanthemum, semen cassiae, mulberry leaves and burdock seeds, and the mixing ratio of the mixture is set to 3:1:3:1. The chrysanthemum is set to Hangzhou chrysanthemum from Zhejiang Province. The chrysanthemum can also be set to other chrysanthemums that are easily available, such as Chuju and the like.

[0054] The liver yin nourishing combination is set as a mixture of Ophiopogon japonicus, Rehmannia glutinosa, Polygonatum sibiricum and Lycium barbarum, and the mixing ratio of the mixture is set to 3:1:1:5.

[0055] The auxiliary materials are set as a mixture of white peony root, wolfberry and salvia miltiorrhiza. Salvia miltiorrhiza has been irradiated. Salvia miltiorrhiza can also be replaced with targeted ginseng substances such as Codonopsis pilosula, and the mixing ratio of the mixture is set to 3:2:1.

[0056] A method for preparing a preparation for protecting liver damage, repairing and nourishing the liver made from a variety of Chinese herbal medicines, comprising the following steps:

[0057] Step 1, weigh the Chinese medicine according to the above weight;

[0058] Step 2: Put the weighed Chinese medicine into water for washing, and set the washing time to three minutes;

[0059] Step 3: Put the cleaned raw materials into a medicine cooker with water and cook them for 50 minutes;

[0060] Step 4: After the medicine is cooked, the medicine is obtained, and then it is naturally cooled and then packaged in a quantitative manner.

[0061] Comparison example

[0062] This embodiment includes a liver-clearing and bile-promoting combination, a liver-soothing and qi-promoting combination, a liver-clearing and eyesight-improving combination, a liver-tonifying and yin-tonifying combination, main ingredients and auxiliary ingredients, and is characterized in that the weight and mass proportions of each raw material are as follows: 10 parts of the liver-clearing and bile-promoting combination, 30 parts of the liver-soothing and qi-promoting combination, 40 parts of the liver-clearing and eyesight-improving combination, 10 parts of the liver-tonifying and yin-tonifying combination, 10 parts of the main ingredient and 20 parts of the auxiliary ingredient.

[0063] The liver-clearing and gallbladder-promoting combination is set as a mixture of Artemisia capillaris, Bupleurum chinense and Gardenia jasminoides. Other more cost-effective Chinese medicines can also be designed, and the mixing ratio of the mixture is set to 3:1:1. The origin of Artemisia capillaris is set to Shanxi Province or Hebei Province, and the origin of Bupleurum chinense and Gardenia jasminoides is set to Sichuan Province.

[0064] The combination for soothing the liver and promoting qi is set as a mixture of honeysuckle and bergamot. Other Chinese medicines with higher cost performance can also be designed, and the mixing ratio of the mixture is set to 3:1. The origin of honeysuckle is set to Tibet Autonomous Region or Sichuan Province, and the origin of bergamot is set to Guangdong Province.

[0065] The liver-clearing and eyesight-improving combination is set as a mixture of chrysanthemum, semen cassiae, mulberry leaves and burdock seeds, and the mixing ratio of the mixture is set to 3:1:3:1. The chrysanthemum is set to Hangzhou chrysanthemum from Zhejiang Province. The chrysanthemum can also be set to other chrysanthemums that are easily available, such as Chuju and the like.

[0066] The liver yin nourishing combination is set as a mixture of Ophiopogon japonicus, Rehmannia glutinosa, Polygonatum sibiricum and Lycium barbarum, and the mixing ratio of the mixture is set to 3:1:1:5.

[0067] The auxiliary materials are set as a mixture of white peony root, wolfberry and salvia miltiorrhiza. Salvia miltiorrhiza has been irradiated. Salvia miltiorrhiza can also be replaced with targeted ginseng substances such as Codonopsis pilosula, and the mixing ratio of the mixture is set to 3:2:1.

[0068] A method for preparing a preparation for protecting liver damage, repairing and nourishing the liver made from a variety of Chinese herbal medicines, comprising the following steps:

[0069] Step 1, weigh the Chinese medicine according to the above weight;

[0070] Step 2: Put the weighed Chinese medicine into water for washing, and set the washing time to three minutes;

[0071] Step 3: Put the cleaned raw materials into a medicine cooker with water and cook them for 30 minutes;

[0072] Step 4: After the medicine is cooked, the medicine is obtained, and then it is naturally cooled and then packaged in a quantitative manner.

[0073] Comprehensive comparison of multiple experiments shows that the effects of Example 1, Example 2 and Example 3 are better than those of the control example, and among Example 1, Example 2 and Example 3, Example 3 has better effects than Example 1 and Example 2.

[0074] It should be noted that, in this document, relational terms such as one and two are merely used to distinguish one entity or operation from another entity or operation, but do not necessarily require or imply any actual relationship or order between these entities or operations.

[0075] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A preparation for protecting liver damage, repairing and nourishing the liver made of a variety of Chinese herbal medicines, including a liver-clearing and gallbladder-invigorating combination, a liver-soothing and qi-promoting combination, a liver-clearing and eye-improving combination, a liver-tonifying and yin-replenishing combination, a main ingredient and an auxiliary ingredient, characterized in that: The weight and mass proportions of each raw material are as follows: 20-30 parts of the liver-clearing and bile-promoting combination, 10-20 parts of the liver-soothing and qi-promoting combination, 10-20 parts of the liver-clearing and eyesight-improving combination, 20-30 parts of the liver-tonifying and yin-tonifying combination, 20-30 parts of the main ingredient and 30-40 parts of the auxiliary ingredient.

2. The preparation for protecting liver damage, repairing and nourishing the liver made of a variety of Chinese herbal medicines according to claim 1, characterized in that: The liver-clearing and gallbladder-promoting combination is set as a mixture of Artemisia capillaris, Bupleurum chinense and Gardenia jasminoides, and the mixing ratio of the mixture is set to 3:1:

1.

3. The preparation for protecting liver damage, repairing and nourishing the liver made of multiple Chinese herbal medicines according to claim 2, characterized in that: The origin of the Artemisia capillaris is set to Shanxi Province or Hebei Province, and the origin of Bupleurum and Gardenia jasminoides is set to Sichuan Province.

4. The preparation for protecting liver damage, repairing and nourishing the liver made of a variety of Chinese herbal medicines according to claim 1, characterized in that: The liver-soothing and qi-promoting combination is set as a mixture of honeysuckle and bergamot, and the mixing ratio of the mixture is set to 3:

1.

5. The preparation for protecting liver damage, repairing and nourishing the liver made of a variety of Chinese herbal medicines according to claim 4, characterized in that: The origin of the honeysuckle is set to Tibet or Sichuan, and the origin of the bergamot is set to Guangdong.

6. The preparation for protecting liver damage, repairing and nourishing the liver made of a variety of Chinese herbal medicines according to claim 1, characterized in that: The liver-clearing and eyesight-improving combination is set as a mixture of chrysanthemum, semen cassiae, mulberry leaves and burdock seeds, and the mixing ratio of the mixture is set to 3:1:3:

1. The chrysanthemum is set to be chrysanthemum from Zhejiang Province.

7. The preparation for protecting liver damage, repairing and nourishing the liver made of a variety of Chinese herbal medicines according to claim 1, characterized in that: The liver yin nourishing combination is set as a mixture of Ophiopogon japonicus, Rehmannia glutinosa, Polygonatum sibiricum and Lycium barbarum, and the mixing ratio of the mixture is set to 3:1:1:

5.

8. The preparation for protecting liver damage, repairing and nourishing the liver made of a variety of Chinese herbal medicines according to claim 1, characterized in that: The main ingredient is set as a mixture of Hovenia dulcis, Poria cocos, Alisma orientalis and dried orange peel, and the mixture is mixed in equal proportions. The auxiliary material is set as a mixture of White Peony Root, Lycium barbarum and Salvia miltiorrhiza, and the mixing ratio of the mixture is set to 3:2:

1.

9. A method for preparing a preparation for protecting liver damage, repairing and nourishing the liver made from a plurality of Chinese herbal medicines as claimed in any one of claims 1 to 8, characterized in that: The following steps are involved: Step 1, weigh the Chinese medicine according to the above weight; Step 2: Put the weighed Chinese medicine into water for washing; Step 3: Put the cleaned raw materials into a medicine cooker with water to cook the medicine; Step 4: After the medicine is cooked, the medicine is obtained, and then it is naturally cooled and then packaged in a quantitative manner.

10. The method for preparing a preparation for protecting liver damage, repairing and nourishing the liver made of a variety of Chinese herbal medicines according to claim 9, characterized in that: The cleaning time of step 2 is set to three minutes, and the boiling time of step 3 is set to 40-60 minutes.