Traditional Chinese medicine composition for tonifying spleen and stopping diarrhea as well as preparation method and application of traditional Chinese medicine composition

Abstract

The traditional Chinese medicine composition is prepared from the following components in parts by weight: 15 to 20 parts of fructus alpiniae oxyphyllae, 15 to 20 parts of rhizoma atractylodis macrocephalae, 10 to 15 parts of fructus psoraleae, 15 to 20 parts of poria cocos, 15 to 20 parts of rhizoma dioscoreae, 10 to 15 parts of fructus schizandrae and 5 to 10 parts of fructus amomi rotundus. The traditional Chinese medicine composition disclosed by the invention has the effects of warming the middle warmer and strengthening the spleen, replenishing qi and strengthening the spleen, eliminating dampness and strengthening the spleen, relieving diarrhea with astringents and promoting digestion and arresting vomiting, can regulate various stress gastrointestinal dysfunctions and improve diarrhea by regulating the functions of the spleen and the stomach and promoting digestion and nutrient absorption of the spleen and the stomach, and is relatively good in curative effect. The traditional Chinese medicine composition and feed are mixed for feeding, active ingestion is adopted, the administration route is more flexible and convenient, and the palatability is good.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicines, and in particular to a spleen-strengthening and diarrhea-stopping traditional Chinese medicine composition, a preparation method and application thereof. Background Art

[0002] Diarrhea is the most common disease in animal breeding, with loose stools and even watery stools as the main symptom. The spleen rises and is responsible for transporting and transforming the essence of water and grain and water and moisture. It is the "foundation of acquired nature and the source of qi and blood biochemistry". In modern breeding, animals are often affected by many stress factors such as transportation, group transfer, weaning, and climate change, which causes the spleen and stomach to fail to function properly, resulting in unclear distinction between clear and turbid, undigested water and grain, and retention of water and moisture, which leads to indigestion, growth and development stunting, low immunity, decreased anti-stress ability, diarrhea, abdominal distension and other symptoms. Clinically, antibiotics are often used to prevent and treat animal diarrhea and improve animal growth performance. Long-term and large-scale use not only affects the normal intestinal microbial colonies of the body, may cause adverse reactions such as intestinal dysfunction, and also cause problems such as drug resistance and drug residues. At present, my country explicitly prohibits the use of antibiotics as feed additives to improve animal growth regulation. Traditional Chinese medicine is a green, environmentally friendly and natural substance with many advantages such as ease of use, safety and effectiveness, low drug residues, and low toxic and side effects. Therefore, regulating and strengthening the spleen and stomach functions through traditional Chinese medicine can effectively improve the digestion and absorption function of animals, promote animal growth and development, and enhance the body's resistance, providing an important guarantee for the prevention and treatment of spleen deficiency diarrhea and healthy animal breeding. Summary of the invention

[0003] Purpose of the invention: The technical problem to be solved by the present invention is to provide a spleen-strengthening and diarrhea-stopping Chinese medicine composition and its preparation method and application in view of the deficiencies in the prior art. By regulating and strengthening the spleen and stomach functions through Chinese medicine, the digestion and absorption function of animals can be effectively improved, the growth and development of animals can be promoted, and the body's resistance can be improved, which provides an important guarantee for the prevention and treatment of spleen deficiency diarrhea and the healthy breeding of animals.

[0004] In order to solve the above technical problems, the present invention provides a Chinese medicine composition for strengthening the spleen and stopping diarrhea.

[0005] Another technical problem to be solved by the present invention is to provide a method for preparing the spleen-strengthening and diarrhea-stopping Chinese medicine composition.

[0006] Another technical problem to be solved by the present invention is to provide application of the above spleen-strengthening and diarrhea-stopping Chinese medicine composition.

[0007] Specifically, the present invention provides a Chinese medicine composition for strengthening the spleen and stopping diarrhea, which comprises the following components in parts by weight: 15-20 parts of Alpinia oxyphylla, 15-20 parts of Atractylodes macrocephala, 10-15 parts of Psoralea corylifolia, 15-20 parts of Poria cocos, 15-20 parts of Dioscorea opposita, 10-15 parts of Schisandra chinensis and 5-10 parts of Cardamom.

[0008] In some specific embodiments, the traditional Chinese medicine composition comprises the following components in parts by weight: 18 parts of Alpinia oxyphylla, 18 parts of Atractylodes macrocephala, 12 parts of Psoralea corylifolia, 18 parts of Poria cocos, 18 parts of Dioscorea opposita, 12 parts of Schisandra chinensis and 8 parts of Amomum villosum.

[0009] In another embodiment, the Chinese medicine composition comprises the following components in parts by weight: 20 parts of Alpinia oxyphylla, 20 parts of Atractylodes macrocephala, 15 parts of Psoralea corylifolia, 20 parts of Poria cocos, 20 parts of Dioscorea opposita, 15 parts of Schisandra chinensis and 10 parts of Cardamom.

[0010] The dosage form of the Chinese medicine composition is any one of powder, oral preparation, pill, powder, tablet, paste, granule and capsule.

[0011] The present invention also provides a method for preparing the above-mentioned Chinese medicine composition, which comprises drying, crushing, sieving and mixing the raw materials of each component in the formula. Preferably, the sieving is through a 100-mesh sieve.

[0012] The above preparation method may further include a concentration process and / or a drying process according to the requirements of the dosage form, or further add common auxiliary materials to prepare oral preparations, pills, powders, tablets, pastes, granules or capsules, etc.

[0013] The present invention further proposes the use of the above-mentioned Chinese medicine composition in preparing a preparation for preventing or treating diarrhea in animals.

[0014] Wherein, the diarrhea is caused by spleen deficiency.

[0015] The preparation is a veterinary drug or a feed additive.

[0016] When the preparation is a feed additive, the addition amount of the traditional Chinese medicine composition in the feed is 0.5-2.0wt%.

[0017] Preferably, the animals are pigs, cattle, sheep, dogs and cats.

[0018] Among the various Chinese medicines in the above formula:

[0019] Alpinia oxyphylla: spicy and warm in nature; it has the effects of warming the spleen, warming the kidneys, and consolidating Qi. It is mainly used to treat cold diarrhea and abdominal pain caused by spleen yang deficiency and abnormal transportation and transformation.

[0020] Atractylodes: sweet, slightly bitter, warm in nature; has the effects of tonifying the spleen and stomach, drying dampness and promoting diuresis, and calming the fetus. It is mainly used to treat spleen deficiency diarrhea, abdominal distension due to loss of appetite, fetal movement disorder, and spontaneous sweating due to physical weakness.

[0021] Psoralea corylifolia: It tastes pungent and bitter, and is warm in nature; it has the effects of tonifying kidney yang and stopping diarrhea, and is mainly used to treat diarrhea due to spleen and kidney yang deficiency, cough and asthma due to deficiency of cold, etc.

[0022] Poria: sweet in taste, neutral in nature; has the effects of dissipating dampness and promoting diuresis, benefiting the spleen and calming the mind, and is mainly used to treat spleen deficiency diarrhea, edema, etc.

[0023] Yam: sweet in taste, neutral in nature; it has the effects of nourishing the spleen and stomach, benefiting the lungs and kidneys, and is mainly used to treat spleen deficiency, poor appetite, diarrhea, lung deficiency, fatigue and cough, and kidney deficiency, frequent urination, etc.

[0024] Schisandra: sour, sweet, warm in nature; has the effects of astringing the intestines and stopping diarrhea, astringing the lungs and relieving asthma. It is mainly used to treat asthma due to lung and kidney deficiency, diarrhea due to spleen and kidney yang deficiency, frequent urination, etc.

[0025] Cardamom: spicy in taste, warm in nature; it has the effects of invigorating the spleen and eliminating dampness, promoting qi and warming the middle, and stimulating appetite and digestion. It is mainly used to treat spleen cold and food stagnation, cold and painful diarrhea, stomach cold and vomiting, etc.

[0026] Among them, Yiqi cures diarrhea and abdominal pain caused by spleen deficiency and cold disorder, and is the main drug; Baizhu nourishes the spleen and stomach, Bupleurum warms the middle and stops diarrhea, Chinese yam nourishes the spleen and kidney, and Poria removes dampness, which are all ministerial drugs, assisting Yiqi to warm and nourish the spleen and stomach and improve spleen and stomach function; Schisandra astringes the intestines and stops diarrhea as an adjuvant; Cardamom removes dampness and wakes up the spleen, warms the middle and helps digestion, and stops vomiting as a guiding drug. The combined use of these drugs has a wide range of effects, and has a good effect on repairing and regulating gastrointestinal function. The Chinese medicine composition has the effects of warming and nourishing the spleen and stomach, replenishing qi and strengthening the spleen, strengthening the spleen and removing dampness, removing dampness and wakes up the spleen to stop diarrhea, warming the middle and stopping vomiting, and improves diarrhea by regulating spleen and stomach function, promoting spleen and stomach digestion and nutrient absorption, and regulating various stress-induced gastrointestinal dysfunctions, and has a good effect. The Chinese medicine composition is mixed with feed for active feeding, and the route of administration is more flexible and convenient, and the palatability is good. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 The effect of the Chinese medicine composition on the water content of mouse feces, different letters indicate significant differences among the groups;

[0028] Figure 2 This is a picture of mouse feces;

[0029] Figure 3 The effect of the Chinese medicine composition on the body weight of mice, different letters indicate significant differences among different groups at the same time;

[0030] Figure 4 The figure shows the effect of the Chinese medicine composition on the fatigue resistance of mice. Different letters indicate significant differences among the groups. DETAILED DESCRIPTION

[0031] The present invention can be better understood according to the following examples. However, it is easy for those skilled in the art to understand that the specific material ratios, process conditions and results described in the examples are only used to illustrate the present invention, and should not and will not limit the present invention described in detail in the claims.

[0032] Traditional Chinese medicine has complex properties and diverse effects. The main drug in the prescription and the compatibility between the drugs are important factors that determine the efficacy of the prescription. In order to ensure the reliability and scientificity of the experimental results, we combined the theory of Chinese veterinary syndrome differentiation, the properties of traditional Chinese medicine and the compatibility relationship, and formulated 6 traditional Chinese medicine compositions for the treatment of spleen deficiency diarrhea. Under the same experimental conditions, the spleen-strengthening and antidiarrhea effects of the example traditional Chinese medicine compositions 1-3 and the comparative example traditional Chinese medicine compositions 4-6 were observed and analyzed, aiming to study and obtain an innovative compound with unique efficacy for spleen deficiency diarrhea.

[0033] Example 1 Preparation of Chinese medicine composition 1.

[0034] The Chinese medicine composition 1 is composed of the following components in parts by weight:

[0035] 15 parts of Alpinia oxyphylla, 15 parts of Atractylodes macrocephala, 10 parts of Psoralea corylifolia, 15 parts of Poria cocos, 15 parts of Dioscorea opposita, 10 parts of Schisandra chinensis, and 5 parts of Cardamom.

[0036] The preparation method is as follows:

[0037] (1) Dry, crush and sieve the above raw materials according to conventional methods;

[0038] (2) Physically mix the sieved raw materials according to the above weight ratio to form a solid powder, and then pack them in vacuum packaging bags to obtain a solid powder.

[0039] Example 2 Preparation of Chinese medicine composition 2.

[0040] The Chinese medicine composition 2 is composed of the following components in parts by weight:

[0041] 18 parts of Alpinia oxyphylla, 18 parts of Atractylodes macrocephala, 12 parts of Psoralea corylifolia, 18 parts of Poria cocos, 18 parts of Dioscorea opposita, 12 parts of Schisandra chinensis, and 8 parts of Cardamom.

[0042] The production method is the same as in Example 1.

[0043] Example 3 Preparation of Chinese medicine composition 3.

[0044] The Chinese medicine composition 3 is composed of the following components in parts by weight:

[0045] 20 parts of Alpinia oxyphylla, 20 parts of Atractylodes macrocephala, 15 parts of Psoralea corylifolia, 20 parts of Poria cocos, 20 parts of Dioscorea opposita, 15 parts of Schisandra chinensis, and 10 parts of Cardamom.

[0046] The production method is the same as in Example 1.

[0047] Comparative Example 1: Preparation of Chinese medicine composition 4.

[0048] The Chinese medicine composition 4 is composed of the following components in parts by weight: 18 parts of Codonopsis pilosula, 18 parts of Atractylodes macrocephala, 18 parts of Poria cocos, 18 parts of Dioscorea opposita, 12 parts of dried ginger, 10 parts of Schisandra chinensis, 10 parts of Patchouli, 8 parts of Amomum villosum, and 5 parts of Cardamom.

[0049] In this formula, the main drug Alpinia oxyphylla in the embodiment is replaced by Codonopsis pilosula, and Psoralea corylifolia is replaced by dried ginger, which together with Atractylodes macrocephala, Poria cocos and Dioscorea opposita serve as assistant drugs. Patchouli and Amomum villosum are added, which together with Schisandra chinensis serve as adjuvant drugs; and Cardamom is the guiding drug.

[0050] The production method is the same as in Example 1.

[0051] Comparative Example 2: Preparation of Chinese medicine composition 5.

[0052] The Chinese medicine composition 5 is composed of the following components in parts by weight: 15 parts of psoralea corylifolia, 15 parts of atractylodes macrocephala, 15 parts of Poria cocos, 15 parts of yam, 10 parts of Evodia rutaecarpa, 10 parts of dried ginger, 12 parts of Schisandra chinensis, and 12 parts of nutmeg.

[0053] In this prescription, the main drug Alpinia oxyphylla in the embodiment is replaced by Psoralea corylifolia; Psoralea corylifolia is replaced by Evodia rutaecarpa and dried ginger, and together with Atractylodes macrocephala, Poria cocos and Dioscorea opposita are used as ministerial drugs; Schisandra chinensis is used as an adjuvant drug; and the auxiliary drug Cardamom is replaced by Nutmeg.

[0054] The production method is the same as in Example 1.

[0055] Comparative Example 3: Preparation of Chinese medicine composition 6.

[0056] The Chinese medicine composition 6 is composed of the following components in parts by weight: 18 parts of Alpinia oxyphylla, 18 parts of Atractylodes lancea, 15 parts of Poria cocos, 15 parts of Dioscorea opposita, 12 parts of Evodia rutaecarpa, 12 parts of Myristica fragrans, and 10 parts of Platycodon grandiflorum.

[0057] This prescription uses Alpinia oxyphylla as the main drug; the Atractylodes macrocephala in the embodiment is replaced by Atractylodes lancea, Psoralea corylifolia is replaced by Evodia rutaecarpa, and they are together with Poria cocos and Dioscorea opposita as assistant drugs; the adjuvant Schisandra chinensis is replaced by Nutmeg; and the assistant drug Cardamom is replaced by Platycodon grandiflorum.

[0058] The production method is the same as in Example 1.

[0059] Example 4 The regulating effect of the Chinese medicine composition on animals with spleen deficiency.

[0060] Preparation of spleen deficiency mouse model: Xiao Chengqi decoction was continuously administered to mice for 5-7 days, 0.5 mL / d per mouse. The mice in the control group were administered with normal saline, and the spirit, appetite, feces, anus, limb activity, and coat smoothness of each mouse were observed and recorded every day until the standard symptoms of spleen deficiency animal model appeared.

[0061] According to the evaluation criteria for the symptoms of spleen deficiency animal models in the "Guidelines for Clinical Research on Traditional Chinese Medicine for the Treatment of Spleen Deficiency Syndrome": ① severe diarrhea, even rectal prolapse; ② poor appetite; ③ emaciation and weight loss; ④ listless demeanor, limbs cannot be retracted, and fur is withered; ⑤ curled up in a pile.

[0062] Mouse feces are divided into: normal feces, normal-looking but watery feces, abnormal-looking soft feces, watery feces, and mucous feces. Abnormal-looking soft feces, watery feces, and mucous feces are considered diarrhea.

[0063] After successful modeling, the mice were randomly divided into model group, Chinese medicine group 1, Chinese medicine group 2, Chinese medicine group 3, Chinese medicine group 4, Chinese medicine group 5 and Chinese medicine group 6, with 10 mice in each group. Ten normal mice were set up as the control group. The mice in the control group and the model group were fed a normal basal diet, and the mice in the Chinese medicine groups 1-6 were respectively fed with 1.5wt% Chinese medicine composition 1-6 in the basal diet for 9 days. The mice were weighed on the 0th, 4th, 9th and 14th days of the experiment. The feces of the mice were observed every day to evaluate the therapeutic effect of diarrhea. The water content of the feces was detected. The fatigue resistance of each group of mice was tested by swimming test.

[0064] Cure: The mouse's mental state, reaction and feeding have basically returned to normal, its activity has increased, its fur is smooth, and its feces are normal or normal in appearance but contains a lot of water. It is considered cured.

[0065] Feces moisture content detection: Mouse feces were collected and weighed, recorded as feces wet weight, and the feces were dried at 100°C to constant weight, then weighed, recorded as feces dry weight, and the feces moisture content was calculated, where feces moisture content = (feces wet weight - feces dry weight) / feces wet weight × 100%.

[0066] Statistical analysis: SPSS 18.0 was used for statistical analysis, and one-way ANOVA was used to test the significance of differences.

[0067] The experimental results are as follows:

[0068] 1. Clinical manifestations

[0069] The mice in the control group were in good spirits, had smooth and neat fur, were responsive, had normal defecation, and had normal feces with smooth surface and hard texture. The mice in the model group huddled together, squinted their eyes and arched their backs, had unkempt fur, had poor appetite, shivered, stood unsteadily, had soft and loose feces with abnormal appearance, and had feces stains on the filter paper. After 5-9 days of medication, the reaction of mice in TCM group 2 gradually returned to normal, their feeding and activities were normal, their fur was smooth, and the texture of their feces gradually became hard, with a normal appearance, similar to that of the control group, and normal granular feces; the activity of mice in TCM group 1 and TCM group 3 increased, their feeding basically returned to normal, and their fur was smooth and clean; the shape of the feces of mice in TCM group 1 gradually returned to normal, with some soft, sticky and deformed; the shape of the feces of mice in TCM group 3 basically returned to normal, with some surfaces not smooth; some mice in TCM groups 4-6 had rough fur, poor mental state, slow reaction, and unwillingness to move, and a few even squinted their eyes and had poor appetite; some mice in TCM groups 4 and 5 had abnormal feces, and their texture was soft, sticky and deformed; some mice in TCM group 6 had thin and shapeless feces, with occasional irregular particles ( Figure 1 ).

[0070] 2. Diarrhea cure rate

[0071] like Figure 1 As shown in Table 1, the use of the Chinese medicine composition has a good curative effect on mouse diarrhea, and the curative effects of Chinese medicine groups 1-3 are better than those of Chinese medicine groups 4-6, among which Chinese medicine group 2 has the best curative effect, with a cure rate of 100%. The feces of mice in Chinese medicine group 1 are normal in appearance but have a lot of water, and some are soft and easily deformed. The feces of mice in Chinese medicine group 2 are healthy feces with normal appearance, and the feces of mice in Chinese medicine group 3 are normal in appearance, but some are not smooth; while the feces of Chinese medicine groups 4-6 are soft and watery, with abnormal appearance, and even unformed loose feces.

[0072] Table 1 The curative effect of Chinese medicine composition on diarrhea in mice

[0073]

[0074] 3. Moisture content of feces

[0075] After the mice were given the medicine, the fecal moisture content of the mice in the TCM groups 1-6 was significantly lower than that in the model group, decreasing by 17.99% (P < 0.05), 25.53% (P < 0.05), 19.37% (P < 0.05), 10.34% (P < 0.05), 9.18% (P < 0.05) and 9.06% (P < 0.05), respectively. The fecal moisture content of the mice in the TCM group 2 was not significantly different from that in the control group (P > 0.05), while the fecal moisture content of the mice in the other TCM groups was significantly higher than that in the control group (P < 0.05). The fecal moisture content of the mice in the TCM groups 2 and 3 was significantly lower than that in the TCM groups 4-6 (P < 0.05) ( Figure 2 ). The above results show that after the mice were treated with the medicine, the spleen's function of transporting water and moisture was improved to varying degrees, and the water content of feces was significantly reduced. Compared with Chinese medicine compositions 4-6, Chinese medicine compositions 1-3 can better improve the spleen's function of transporting water and moisture, especially Chinese medicine composition 2 has the best spleen-strengthening effect.

[0076] Conclusion: Compared with Chinese medicine composition 4-6, Chinese medicine composition 1-3 can more effectively improve spleen and stomach function, strengthen the function of spleen and stomach in transporting and transforming water and dampness, effectively reduce the fecal water content of mice, and have a better therapeutic effect on diarrhea. In particular, Chinese medicine composition 2 has a cure rate of 100% for diarrhea, and has the best effect of improving spleen and stomach function and stopping diarrhea. Chinese medicine composition 4-6 uses other tonic drugs of the same type as Alpinia oxyphylla and Psoralea corylifolia as the main drugs, and is combined with drugs with similar effects of warming the middle, replenishing qi, transforming dampness, and stopping diarrhea. The cure rate of diarrhea is only 30% and 50%, indicating that simple replacement or addition and subtraction of drugs of the same type or drugs with similar functions in the formula may not necessarily achieve the expected synergistic effect, thereby obtaining the same therapeutic effect. Reliable prescriptions should not only be highly targeted, just in the condition, rigorous in formulating, with clear priorities in the use of drugs, and good at clever compatibility, but also must be verified by experimental research to judge the advantages and disadvantages of the synergistic combination of the formula.

[0077] We further selected Chinese herbal compositions 1-3 with stronger spleen-strengthening effects and tested their effects on the body weight and fatigue resistance of mice.

[0078] 4. Weight changes:

[0079] After using the Chinese medicine composition for 1-3 days, the weight changes of mice in each group were as follows: Figure 3 As shown, the weight of mice in each group gradually increased with age, and the weight of mice in Chinese medicine group 1 was significantly higher than that of the model group by 8.31% on the 9th day (P<0.05). The weight of mice in Chinese medicine group 2 was significantly higher than that of mice in the model group by 8.99%, 15.17% and 18.51% on the 4th, 9th and 14th days (P<0.05), respectively, and there was no significant difference with the control group on the 14th day; the weight of mice in Chinese medicine group 3 was also significantly higher than that of the model group on the 4th, 9th and 14th days (P<0.05), which was 3.41%, 8.23% and 6.76% higher, respectively, but significantly lower than that of Chinese medicine group 2 on the 9th and 14th days (P<0.05); the results showed that Chinese medicine compositions 2 and 3 can significantly improve the function of spleen deficiency in mice to transport water and grain essence, enhance the digestive function of spleen and stomach, promote animal growth and development, and significantly increase weight, among which Chinese medicine composition 2 has better effect.

[0080] 5. Fatigue resistance:

[0081] After oral administration of Chinese medicine compositions 1-3, mice in each group were subjected to swimming fatigue resistance test. The results are as follows: Figure 4As shown in the results, the mice in the control group could swim for an average of 8.36 minutes, while the mice in the model group swam for an average of 2.95 minutes and drowned twice, which was significantly lower than that in the control group (P < 0.01). The mice in the Chinese medicine group 1 swam for an average of 3.96 minutes, which was not significantly different from the model group (P>0.05), and there was no drowning. The mice in the Chinese medicine group 2 swam for an average of 7.95 minutes, which was significantly higher than the model group, Chinese medicine groups 1 and 3 (P < 0.05), and was not significantly different from the control group (P>0.05). The mice in the Chinese medicine group 3 swam for an average of 5.88 minutes, which was significantly higher than the model group and lower than the control group (P < 0.05). This shows that the fatigue resistance of mice was effectively improved after administration, among which the Chinese medicine composition 2 had the best effect, which can effectively repair the spleen and stomach function and enhance the body's resistance.

[0082] In summary, it was observed through experiments that the components in the Chinese medicine compositions 1-3 of the embodiments cooperate with each other to more comprehensively regulate the physiological functions of the spleen and stomach, which can not only strengthen the spleen and stomach's function of transporting water and moisture, effectively reduce the water content of mice's feces, and have a good curative effect on diarrhea, but also effectively improve the spleen and stomach's functions of digestion and transporting water and grain essence, promote digestive function, increase mice's weight and fatigue resistance, and improve animals' growth performance and resistance. In particular, Chinese medicine composition 2 has an unexpected therapeutic effect.

[0083] Finally, it should be noted that the above is only an example of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned implementation, it is still possible for a person skilled in the art to modify the technical solution recorded in the aforementioned implementation, or to perform equivalent replacement of part thereof. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention. Although the above describes the specific implementation mode of the present invention, it is not intended to limit the protection scope of the present invention. A person skilled in the art should understand that, based on the technical solution of the present invention, various modifications or deformations that can be made by those skilled in the art without creative labor are still within the protection scope of the present invention.

Claims

1. A Chinese medicine composition for strengthening the spleen and stopping diarrhea, characterized in that: The Chinese medicine composition comprises the following components in parts by weight: 15-20 parts of Alpinia oxyphylla, 15-20 parts of Atractylodes macrocephala, 10-15 parts of Psoralea corylifolia, 15-20 parts of Poria cocos, 15-20 parts of Dioscorea opposita, 10-15 parts of Schisandra chinensis and 5-10 parts of Cardamom.

2. The Chinese medicine composition according to claim 1, characterized in that: The traditional Chinese medicine composition comprises the following components in parts by weight: 18 parts of Alpinia oxyphylla, 18 parts of Atractylodes macrocephala, 12 parts of Psoralea corylifolia, 18 parts of Poria cocos, 18 parts of Dioscorea opposita, 12 parts of Schisandra chinensis and 8 parts of Amomum villosum.

3. The Chinese medicine composition according to claim 1, characterized in that The traditional Chinese medicine composition comprises the following components in parts by weight: 20 parts of Alpinia oxyphylla, 20 parts of Atractylodes macrocephala, 15 parts of Psoralea corylifolia, 20 parts of Poria cocos, 20 parts of Dioscorea opposita, 15 parts of Schisandra chinensis and 10 parts of Amomum villosum.

4. The Chinese medicine composition according to any one of claims 1 to 3, characterized in that: The dosage form of the Chinese medicine composition is any one of powder, oral preparation, pill, powder, tablet, paste, granule and capsule.

5. The method for preparing the Chinese medicine composition according to any one of claims 1 to 3, characterized in that: The raw materials of each component in the formula are dried, crushed, sieved and mixed to obtain the product.

6. Use of the Chinese medicine composition according to any one of claims 1 to 3 in the preparation of a preparation for preventing or treating diarrhea in animals.

7. The use according to claim 6, characterized in that: The diarrhea is diarrhea caused by spleen deficiency.

8. The use according to claim 6, characterized in that: The preparation is a veterinary drug or a feed additive.

9. The use according to claim 6, characterized in that: When the preparation is a feed additive, the amount of the Chinese medicine composition added to the feed is 0.5-2.0wt%.

10. The use according to claim 6, characterized in that: The animals are pigs, cattle, sheep, dogs and cats.

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