Tumor electric field treatment system and control method thereof

Abstract

The invention provides a tumor electric field treatment system and a control method thereof, and the method comprises the steps: controlling a second pair of electrode plates to carry out temperature detection under the condition that an alternating current electric signal is applied to a first pair of electrode plates so as to generate an alternating electric field between the first pair of electrode plates, when the second pair of electrode plates is used for temperature detection, the temperature detection ends corresponding to the target row group are switched to be communicated with the corresponding temperature sampling points, and the control switches corresponding to the column groups where the temperature detection units in the target row group are located are controlled to be closed in sequence; analog temperature signals detected by the corresponding one or more combinations of all the temperature detection units in the target row group are sampled based on the corresponding temperature sampling points respectively, and the temperature of each electrode unit in the target row group is determined based on the sampled analog temperature signals respectively. Therefore, the temperature of each electrode unit of the corresponding electrode plate can be comprehensively and accurately controlled, and the pasting of the electrode plate can be facilitated.

Description

[0001] This application is a divisional application of the invention patent application with the application date of October 25, 2024, application number 202411506110.5, and invention name "Tumor electric field therapy system, electrode sheet, tumor treatment equipment and method". Technical Field

[0002] The present application relates to tumor electric field therapy technology, and in particular to a control method for a tumor electric field therapy system, a computer-readable storage medium, and a tumor electric field therapy system. Background Art

[0003] Tumor electric field therapy is a method that uses low-intensity, medium-to-high-frequency alternating electric fields to prevent the formation of spindle microtubules during mitosis in certain tumor cells, inhibit the separation of intracellular organelles during cell division, and induce apoptosis of cells during mitosis, thereby achieving the effect of treating tumors.

[0004] Compared with traditional cancer treatments, tumor electric field therapy has an innovative mechanism of action. Some physiological characteristics of tumor cells, such as geometric shape and high-frequency mitosis, make them susceptible to tumor electric field therapy. Tumor electric field therapy disrupts the normal aggregation of tubulin by exerting directional forces on polar particles (such as macromolecules and organelles) within cells. These processes may lead to physical damage to the cell membrane and cell apoptosis. At the end of cell mitosis, the structural morphology of the cleavage furrow will lead to uneven distribution of the electric field around it. At the same time, under the influence of tumor electric field therapy, the electric field intensity at the cleavage furrow is significantly enhanced, and the charged substances in the cell move toward the cleavage furrow, which interferes with or even destroys the formation of the cell structure, and ultimately leads to cell division failure and apoptosis.

[0005] The tumor electric field therapy system in the related art uses an electric field application device to transmit the alternating electric signal for tumor electric field therapy to the electrode sheet, and then applies the alternating electric field to the patient's tumor site through the electrode sheet for tumor electric field therapy. When the tumor treatment electric field is applied to the patient's body, heat will accumulate at the application site, and the temperature will rise accordingly. Therefore, it is necessary to monitor the temperature of the application site. When the temperature is too high, the electric field strength needs to be adjusted in time to reduce the risk of skin burns caused by excessive temperature.

[0006] The tumor electric field treatment system includes at least one pair of electrode sheets, each of which has multiple electrode units. Even if the same alternating electric signal is applied to each electrode unit, the heat generated by each electrode unit will be different due to its different position, that is, the temperature of each electrode unit on the entire electrode sheet will not be completely consistent. In this way, it is possible that the temperature of some electrode units in the entire electrode sheet exceeds the preset temperature, while the temperature of other electrode units is normal. In order to improve the effect of tumor electric field treatment, it is necessary to implement individual control on the over-temperature electrode units. However, for the electrode sheets in the related art, the individual control of the electrode units requires a conductive trace to be set for each electrode unit in the substrate of the electrode sheet, which will increase the number of conductive traces in the electrode sheet substrate so that the electrode sheet is not easy to bend, and the cable electrically connected to the electrode sheet will also be thickened, which increases the overall weight of the electrode sheet, which is not conducive to the application of the electrode sheet and brings inconvenience to the patient. Summary of the invention

[0007] The present application aims to solve at least one of the technical problems in the related art to a certain extent. To this end, the first purpose of the present application is to propose a control method for a tumor electric field therapy system, which can realize comprehensive and accurate control of the temperature of each electrode unit of the corresponding electrode sheet in the second pair of electrode sheets while applying an alternating current signal to the first pair of electrode sheets through multiplexing of dual-purpose signal lines and controlling a control switch during the operation of the tumor electric field therapy system, and can also facilitate the application of the electrode sheets.

[0008] A second object of the present application is to provide a computer-readable storage medium.

[0009] The third objective of this application is to provide a tumor electric field treatment system.

[0010] To achieve the above-mentioned purpose, the first aspect of the present application provides a control method for a tumor electric field therapy system, wherein the tumor electric field therapy system comprises a first pair of electrode sheets and a second pair of electrode sheets, each of the electrode sheets comprises a plurality of electrode units and a plurality of temperature detection units, each of the electrode units can apply an alternating electric signal, each of the temperature detection units is arranged corresponding to an electrode unit to detect the temperature at the corresponding electrode unit, and the plurality of electrode units are configured into at least two row groups and at least two column groups in terms of circuit connection, the ground terminals of the temperature detection units in each of the column groups are connected to a ground pin through a control switch, and the temperature detection units in each of the row groups are connected in series to form a temperature detection pin. The method comprises: when the first pair of electrode sheets are powered so as to generate an alternating electric field between the first pair of electrode sheets, controlling the second pair of electrode sheets to perform temperature detection, wherein when the second pair of electrode sheets perform temperature detection, switching the temperature detection end corresponding to the target row group to be connected to the corresponding temperature sampling point, and controlling the control switches corresponding to the column group where each temperature detection unit in the target row group is located to be closed in sequence, so that the analog temperature signals detected by the corresponding one or more combinations of all the temperature detection units in the target row group are sampled respectively based on the corresponding temperature sampling points, and determining the temperature at each electrode unit in the target row group based on the respectively sampled analog temperature signals.

[0011] According to the control method of the tumor electric field therapy system of the embodiment of the present application, when an alternating electric field is applied to one pair of electrode sheets in the two pairs of electrode sheets, the other pair of electrode sheets is controlled to perform temperature detection, which not only realizes comprehensive and precise control of the temperature of each electrode unit of the corresponding electrode sheet, but also facilitates the application of the electrode sheet, wherein the multiple electrode units are divided into at least two row groups and at least two column groups in circuit connection, and the ground ends of the temperature detection units corresponding to each electrode unit in each column group are connected to the ground pin through a control switch, the temperature detection units corresponding to each electrode unit in each row group are connected in series, and based on the dual-purpose signal line, the application of alternating electric signals to each electrode unit in each row group and the temperature sampling of the corresponding electrode unit at each temperature sampling point can be completely switched and isolated, thereby avoiding interference and ensuring the accuracy of the temperature sampling signal. Not only is no new AC signal line (i.e., AC line) added, but the original AC signal line is also omitted, so that multiple electrode units can be controlled in partitions using fewer conductive traces.

[0012] Optionally, for each of the electrode sheets, the temperature detection end corresponding to each of the row groups is connected to the first switching end of the corresponding rectifier switching unit, the second switching end of the rectifier switching unit corresponding to each of the row groups is respectively connected to each of the electrode units in the corresponding row group, the fixed end of the rectifier switching unit corresponding to each of the row groups is connected to the fixed end of the corresponding bidirectional switch through a dual-purpose signal line, the first end of the bidirectional switch corresponding to each of the rectifier switching units is the temperature sampling point of the corresponding row group, and the second end of the bidirectional switch corresponding to each of the rectifier switching units is simultaneously connected to the alternating power line, wherein the first pair of electrode sheets is applied with an alternating current signal, including:

[0013] The rectifying switching unit and the bidirectional switch corresponding to the first pair of electrode sheets are controlled to be linked so as to apply an alternating electric signal to the electrode units in the first pair of electrode sheets based on the alternating power line.

[0014] Optionally, for each electrode sheet in the first pair of electrode sheets, when the control switches corresponding to each of the column groups are disconnected and any one of the dual-purpose signal lines is connected to the alternating power line, the second switching end of the rectifier switching unit corresponding to the dual-purpose signal line is controlled to be connected to the fixed end, so that each electrode unit in the row group corresponding to the dual-purpose signal line is applied with the alternating electrical signal based on the alternating power line.

[0015] Optionally, for each electrode sheet in the first pair of electrode sheets, when the control switches corresponding to each of the column groups are disconnected, the multi-channel target dual-purpose signal line is switched to be connected to the alternating power line, and the second switching end of each rectifier switching unit corresponding to the multi-channel target dual-purpose signal line is controlled to be connected to the fixed end, so that each electrode unit in the row group corresponding to the multi-channel target dual-purpose signal line is applied with the alternating electrical signal based on the alternating power line at the same time.

[0016] Optionally, for each electrode sheet in the first pair of electrode sheets, when the control switches corresponding to the column groups are disconnected, the dual-purpose signal lines corresponding to at least two row groups are switched to connect to different alternating power lines, so that the respective electrode units in different row groups are applied with the alternating electric signals based on different alternating power lines.

[0017] Optionally, for each electrode sheet in the second pair of electrode sheets, when the control switch corresponding to the column group where the first temperature detection unit connected to the temperature detection end in the target row group is located is closed, the analog temperature signal detected by the first temperature detection unit is sampled based on the corresponding temperature sampling point.

[0018] Specifically, when the control switch corresponding to the column group where the second temperature detection unit adjacent to the first temperature detection unit in the target row group is located is closed, the analog temperature signal detected by the combination of the first temperature detection unit and the second temperature detection unit is sampled based on the corresponding temperature sampling point; when the control switch corresponding to the column group where the third temperature detection unit adjacent to the second temperature detection unit in the target row group is located is closed, the analog temperature signal detected by the combination of the first temperature detection unit, the second temperature detection unit and the third temperature detection unit is sampled based on the corresponding temperature sampling point; and so on, when the control switch corresponding to the column group where the last temperature detection unit in the target row group is located is closed, the analog temperature signals detected by the combination of the temperature detection units in the target row group are sampled based on the corresponding temperature sampling point.

[0019] Optionally, determining the temperature of each electrode unit in the target row group based on the respectively sampled analog temperature signals includes:

[0020] Determining the temperature at a first electrode unit in the target row group based on the sampled analog temperature signal corresponding to the first temperature detection unit;

[0021] Determine the temperature at the second electrode unit in the target row group based on the sampled analog temperature signal corresponding to the first temperature detection unit and the analog temperature signal corresponding to the combination of the first temperature detection unit and the second temperature detection unit;

[0022] Determine the temperature at the third electrode unit in the target row group based on the sampled analog temperature signal corresponding to the combination of the first temperature detection unit and the second temperature detection unit, and the analog temperature signal corresponding to the combination of the first temperature detection unit, the second temperature detection unit, and the third temperature detection unit;

[0023] By analogy, the temperatures at the fourth electrode unit to the last electrode unit in the target row group are determined.

[0024] Optionally, for each electrode sheet in the second pair of electrode sheets, the temperature detection end corresponding to the switching target row group is connected to a corresponding temperature sampling point, including:

[0025] The rectifying switching unit corresponding to the target row group is controlled to be linked with the corresponding bidirectional switch, so that the temperature detection end corresponding to the target row group is connected to the corresponding temperature sampling point.

[0026] Optionally, when the first end of the bidirectional switch corresponding to the target row group is connected to the fixed end, the fixed end of the rectifier switching unit linked to the bidirectional switch is connected to the first switching end.

[0027] To achieve the above-mentioned purpose, the second embodiment of the present application provides a computer-readable storage medium on which a computer program is stored. When the computer program is executed by a processor, the control method of the aforementioned tumor electric field therapy system is implemented.

[0028] To achieve the above-mentioned purpose, the third aspect of the present application provides a tumor electric field therapy system, including a memory and a controller, wherein the memory stores a computer program, and when the computer program is executed by the controller, the aforementioned control method of the tumor electric field therapy system is implemented.

[0029] The above description is only an overview of the technical solution of the present application. In order to more clearly understand the technical means of the present application, it can be implemented in accordance with the contents of the specification. In order to make the above and other purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are listed below. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 A schematic diagram of a tumor electric field treatment system according to an embodiment of the present application;

[0031] Figure 2 for Figure 1 The schematic diagram of the partition structure of the electrode sheet of the tumor electric field treatment system shown;

[0032] Figure 3 for Figure 1 A schematic diagram of the circuit connection between an electrode sheet and an adapter of the tumor electric field treatment system shown;

[0033] Figure 4 for Figure 1 A schematic structural diagram of an electrode unit of a tumor electric field treatment system is shown;

[0034] Figure 5 for Figure 1 The schematic diagram of the circuit connection between an electrode sheet, an adapter and an electric field generator of the tumor electric field treatment system shown;

[0035] Figure 6 for Figure 1 A schematic block diagram of the internal structure of the adapter of the tumor electric field treatment system shown;

[0036] Figure 7 for Figure 1 A schematic block diagram of the internal structure of an electric field generator of a tumor electric field treatment system is shown;

[0037] Figure 8 A schematic diagram of a flow chart of an electrode sheet temperature detection method according to an embodiment of the present application;

[0038] Fig. 9A schematic diagram of a flow chart of an electrode sheet abnormality detection method according to an embodiment of the present application;

[0039] Fig.10 A schematic flow chart of a control method of a tumor electric field treatment system according to an embodiment of the present application;

[0040] Fig.11 A schematic diagram of a flow chart of an electrode sheet type identification method according to an embodiment of the present application;

[0041] Fig.12 A schematic flow chart of a signal control method for tumor electric field therapy according to an embodiment of the present application;

[0042] Fig.13 A schematic flow chart of an electrode sheet temperature detection method according to another embodiment of the present application;

[0043] Fig.14 A schematic flow chart of a method for applying an alternating electric signal for electric field therapy of tumors according to another embodiment of the present application;

[0044] Fig.15 It is a flow chart of a method for applying an alternating electric signal based on a temperature detection signal according to an embodiment of the present application;

[0045] Fig.16 This is a flow chart of a method for applying an alternating electric signal based on a temperature detection signal according to another embodiment of the present application;

[0046] Fig.17 A schematic diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0047] Fig.18 A schematic diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0048] Fig.19 for Fig.18 A schematic diagram of the circuit connection between an electrode sheet and an adapter of the tumor electric field treatment system shown;

[0049] Fig. 20 A schematic diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0050] Fig.21 A schematic diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0051] Fig. 22 A schematic diagram of the circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0052] Fig.23 A schematic diagram of the circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0053] Fig.23A A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0054] Fig. 23B A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0055] Fig.23C A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0056] Fig.24 A schematic diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0057] Fig.25 for Fig.24 A schematic diagram of the circuit connection between an electrode sheet and an adapter of the tumor electric field treatment system shown;

[0058] Fig.26 A schematic diagram of the circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0059] Fig. 27 A schematic diagram of a tumor electric field treatment system according to another embodiment of the present application;

[0060] Fig.28 A schematic diagram of the circuit connection between an electrode sheet, an adapter, and an electric field generator of a tumor electric field treatment system according to another embodiment of the present application;

[0061] Fig.29 for Fig. 27 A schematic structural diagram of an electrode unit of a tumor electric field treatment system is shown;

[0062] Fig.30 for Fig.28 A schematic block diagram of the internal structure of the adapter of the tumor electric field treatment system shown;

[0063] Fig.31 for Fig.28 A schematic block diagram of the internal structure of an electric field generator of a tumor electric field treatment system is shown;

[0064] Fig.32 A schematic flow chart of a control method of a tumor electric field treatment system according to another embodiment of the present application;

[0065] Fig.33 A schematic flow chart of a signal control method for tumor electric field therapy according to another embodiment of the present application;

[0066] Fig.34A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0067] Fig.35 A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0068] Fig.36 A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0069] Fig.37 A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0070] Fig.38 A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0071] Fig.39 A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0072] Fig.40 A schematic diagram of a circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application;

[0073] Fig.41 This is a schematic diagram of the circuit connection between an electrode sheet and an adapter of a tumor electric field treatment system according to another embodiment of the present application. DETAILED DESCRIPTION

[0074] The following embodiments of the technical solution of the present application are described in detail in conjunction with the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present application, and are therefore only used as examples, and cannot be used to limit the scope of protection of the present application.

[0075] Embodiment 1:

[0076] Figure 1 FIG. 1 is a schematic diagram of a tumor electric field treatment system 100 according to an embodiment of the present application. Figure 1 As shown, the tumor electric field treatment system 100 includes: at least one pair of electrode sheets 13, an adapter 20 connected to the at least one pair of electrode sheets 13, and an electric field generator 30 connected to the adapter 20. The at least one pair of electrode sheets 13 can be arranged in pairs on the patient's body surface, such as Figure 1There are four electrode sheets 13 in the apparatus, and every two electrode sheets 13 are arranged as a pair on the patient's body surface. The electric field generator 30 can be used to supply power to at least one pair of electrode sheets 13, so that an alternating electric field for treating tumors is generated between at least one pair of electrode sheets 13. The adapter 20 is electrically connected between at least one pair of electrode sheets 13 and the electric field generator 30, and is used to transmit the alternating electric signal generated by the electric field generator 30 to at least one pair of electrode sheets 13. In other words, the electric field generator 30 is capable of generating an alternating electric signal, and the generated alternating electric signal is transmitted to each electrode sheet 13 through the adapter 20, so that an alternating electric field for treating tumors is generated between the same pair of electrode sheets 13, so as to apply an alternating electric field to the tumor site of the patient for tumor treatment.

[0077] like Figure 1 As shown, in this embodiment, the number of electrode sheets 13 is 4, each electrode sheet 13 includes a plurality of electrode units 33 of the same number, each electrode unit 33 is electrically connected to the adapter 20, and the number of electrode units 33 on each electrode sheet 13 is 20. In other embodiments, the tumor electric field treatment system 100 may also have more or fewer electrode sheets 13; in other embodiments, each pair of electrode sheets 13 has the same number of electrode units 33, and different pairs of electrode sheets 13 may have different numbers of electrode units 33; in other embodiments, the number of electrode units 33 on each electrode sheet 13 may be 9, 13, etc., which can be configured according to actual conditions.

[0078] In this embodiment, the connection line between two electrode units 33 can be called a connecting strip, and the interval between the electrode units 33 can be adjusted by the connecting strip. If one electrode unit 33 is connected to another electrode unit 33 only by one connecting strip, the electrode unit 33 is an electrode unit 33 at a free end, for example Figure 1Each electrode sheet 13 shown has 9 electrode units 33 at free ends. The surrounding space where the electrode units 33 at the free ends are located is an open space, that is, the electrode units 33 at the free ends have a certain degree of freedom and can move freely in the open space. For example, the connecting belt can be stretched or bent to a certain extent, so that the electrode units 33 can move in all directions. The reason why some electrode units 33 of each electrode sheet 13 are set to be in the form of free ends in this embodiment is that after the electrode sheet is attached to the human body, the electric fields of the electrode units 33 are inconsistent due to the wrinkles of the human skin and the corresponding impedance changes, thereby causing the temperatures of the electrode units 33 to be inconsistent, and the electrode units 33 located at the periphery of the electrode sheet 13 heat faster. Therefore, when some electrode units 33 in the electrode sheet 13 are at the free ends, the electrode units 33 at the free ends can be adjusted to increase the heat dissipation space of the peripheral electrode units 33, accelerate heat dissipation, and avoid local excessive temperature causing low-temperature burns to the human body. In addition, the application position of the electrode unit 33 at the free end on the human body can be adjusted, so that the electrode unit 33 at the free end can be flexibly applied to the human body according to actual needs, thereby improving the comfort of the human body and improving the treatment effect.

[0079] Figure 3 for Figure 1 The circuit connection diagram of the electrode sheet 13 and the adapter 20 of the tumor electric field treatment system 100 is shown. Figure 4 Schematic diagram of the structure of the electrode unit 33 is shown. It is worth noting that: Figure 3 The arrangement of the electrode units 33 shown is to more clearly illustrate the electrical connection between an electrode sheet 13 and the adapter 20. Figure 3 The arrangement of the electrode units 33 shown does not represent the arrangement of the electrode units 33 in a spatial structure. Figure 3 The figure shows the cooperation between the rectifying switching unit 16 and the multiplexing switching unit (including a plurality of bidirectional switching switches 55) to realize the switching between temperature sampling and applying the alternating electrical signal. Figure 3As shown, a plurality of electrode units 33 in an electrode sheet 13 are configured into a plurality of row groups and a plurality of column groups, and a rectifying switching unit 16 having a first switching end 1, a second switching end 2 and a fixed end 3 is provided for each row group, the first switching end 1 of the rectifying switching unit 16 is connected to each temperature detection unit 35 connected in series in the corresponding row group, the second switching end 2 of the rectifying switching unit 16 is respectively connected to each electrode unit 33 in the corresponding row group, and the fixed end 3 of the rectifying switching unit 16 is connected to the multiplexing switching unit through a dual-purpose signal line 19. For example, the first end of the bidirectional switch 55-1 is turned on, the second end is turned off, and the first switching end 1 of the corresponding rectifying switching unit 16 is connected to the fixed end 3, so as to obtain the temperature detection signal of the temperature detection unit 35 of the electrode unit 33 in the corresponding electrode sheet 13; or, the second end of the bidirectional switch 55-1 is turned on, the first end is turned off, and the second switching end 2 of the corresponding rectifying switching unit 16 is connected to the fixed end 3, and the electrode units 33 of the corresponding row group can be applied with an alternating electrical signal at the same time.

[0080] Combination Figure 1 , Figure 3 as well as Figure 4 , the electrode sheet 13 includes: a substrate 31, a plurality of electrode units 33 electrically connected to the substrate 31 at intervals, a plurality of temperature detection units, a plurality of rectifier switching units 16, and a first cable 15 electrically connected to the substrate 31. The substrate 31 may be a flexible circuit board. The substrate 31 is embedded with a plurality of conductive traces, which include a plurality of grounding wires 18, a multi-channel dual-purpose signal wire 19, and a rectifier ground wire (not numbered) for grounding the plurality of rectifier switching units 16. The first cable 15 has a plurality of core conductors (not shown), each of which is electrically connected to the plurality of grounding wires 18, the multi-channel dual-purpose signal wire 19, and the rectifier ground wire (not numbered) of the substrate 31 in a one-to-one correspondence. In this embodiment, the total number of the grounding wires 18, the dual-purpose signal wires 19, and the rectifier ground wire (not numbered) embedded in the substrate 31 does not exceed 10, so the number of conductors of the first cable 15 does not exceed 10.

[0081] The plurality of electrode units 33 are configured into a plurality of row groups and a plurality of column groups. In the present embodiment, 20 electrode units 33 are provided on each electrode sheet 13, and the 20 electrode units 33 are arranged in the order of 1 to 20 in the circuit connection, and are divided into four row groups and five column groups, that is, the 20 electrode units 33 are arranged in four rows and five columns in the circuit connection. Each electrode unit 33 corresponds to a temperature detection unit 35, and each temperature detection unit 35 has a signal terminal 35-2 and a ground terminal 35-1. The electrode unit 33 and the temperature detection unit 35 are both soldered to the substrate 31. Since the plurality of temperature detection units 35 are arranged one-to-one with the plurality of electrode units 33, the plurality of temperature detection units 35 are also arranged in four row groups and five column groups in the circuit connection. It should be noted that the arrangement method here is to more clearly show the electrical connection between the electrode sheet 13 and the adapter 20, and does not represent the arrangement of the electrode unit 33 in the spatial structure, and its spatial structure may be as follows Figure 2 The structure shown as an array may also be other structures, such as petal-shaped or scattered, and may be regular or irregular. The electrode unit 33 is configured to apply an alternating electric field to the patient's tumor site. The temperature detection unit 35 is configured to detect the temperature of the patient's body surface attached to the electrode sheet 13, that is, the temperature at the corresponding electrode unit 33, and output a temperature detection signal to the adapter 20. In this embodiment, the multiplexed dual-purpose signal line 19 of the substrate 31 is respectively arranged in a one-to-one correspondence with the multiple row groups of the electrode unit 33, and is configured to transmit the alternating electric signal generated by the electric field generator 30 to each electrode unit 33 in the corresponding row group. That is, the electrode units 33 in the same row group can be connected to the same dual-purpose signal line 19 of the substrate 31 through the corresponding rectifier switching unit 16, and the electrode units 33 in different row groups are respectively connected in parallel through different dual-purpose signal lines 19 of the substrate 31. The dual-purpose signal line 19 of the substrate 31 is electrically connected to the first cable 15, and then electrically connected to the electric field generator 30 via the adapter 20. Furthermore, the dual-purpose signal line 19 of the substrate 31 receives the alternating electric signal generated by the electric field generator 30 through the first cable 15 and the adapter 20 .

[0082] The multiple grounding wires 18 are respectively arranged in one-to-one correspondence with the multiple column groups of the electrode unit 33, and the multiple grounding wires 18 are respectively used to short-circuit each corresponding temperature detection unit 35 in each column group to the ground. That is, the grounding ends 35-1 of the multiple temperature detection units 35 in the same column group are short-circuited through the same grounding wire 18 of the substrate 31, and the grounding ends 35-1 of the temperature detection units 35 in different column groups are respectively connected in parallel through different grounding wires 18 of the substrate 31. During the time period of temperature detection, only one of the multiple grounding wires 18 is turned on at the same time, and the rest are disconnected. Each temperature detection unit 35 includes a temperature sensor 34, and the two ends of each temperature sensor 34 are respectively a signal end 34-2 and a grounding end 34-1. The multiple temperature sensors 34 located in the same row group are connected in series, and a signal terminal 34-2 located at the end of each row group is connected to a dual-purpose signal line 19 through a corresponding rectifier switching unit 16, and then connected to a DC power supply VCC through a corresponding bidirectional switch 55 and a corresponding voltage divider resistor 53. The ground terminals 34-1 of the corresponding temperature sensors 34 in each column group are connected together through corresponding diodes, and then connected to the control switch 54 through corresponding ground wires in multiple ground wires 18, and then connected to the ground pin GND. The tumor electric field treatment system 100 configures the switching timing of the bidirectional switch 55 and the control switch 54 so that the analog temperature signals detected by the corresponding one or more combinations of all the temperature sensors 34 of the electrode sheet 13 are sampled respectively.

[0083] like Figure 3As shown, all temperature sensors 34 located in the same row group are connected in series into one line, connected to one dual-purpose signal line 19 (such as one of the dual-purpose signal lines 19-1, 19-2, 19-3, and 19-4) through the corresponding rectifier switching unit 16, and then connected to the DC power supply VCC through the corresponding bidirectional switch 55. The grounding ends 34-1 of all temperature sensors 34 located in the same row group are connected to the ground pin GND by five grounding lines 18 (such as grounding lines 18-1, 18-2, 18-3, 18-4, and 18-5), and the grounding ends 34-1 of all temperature sensors 34 located in the same column group are connected to the same grounding line 18 (such as grounding lines 18-1, 18-2, 18-3, 18-4, and 18-5). 3, 18-4, 18-5), each row group of temperature sensors 34 are connected in series with a bidirectional switch 55 (such as a bidirectional switch 55-1, 55-2, 55-3 or 55-4) and a voltage divider resistor 53 (such as a voltage divider resistor R1, R2, R3 or R4) at the DC power supply VCC end, and the voltage divider resistor 53 (such as a voltage divider resistor R1, R2, R3 or R4) is closer to the DC power supply VCC end than the bidirectional switch 55 (such as a bidirectional switch 55-1, 55-2, 55-3 or 55-4), and each ground line 18 is connected in series with a control switch 54 (such as a control switch 54-1, 54-2, 54-3, 54-4 or 54-5).

[0084] In this embodiment, when each electrode unit 33 is equipped with a temperature detection unit 35 for temperature detection, the above-mentioned circuit design is used to reduce the number of wires of the first cable 15, avoid the cable becoming thicker, the cable becoming harder and increasing the difficulty of cable fixing; at the same time, avoid the increase in the number of wires of the first cable 15 affecting the adhesion effect between the electrode sheet 13 and the body surface corresponding to the patient's tumor site. The grounding wire 18, the dual-purpose signal wire 19 and the rectifier ground wire (unnumbered) embedded in the substrate 31 are 10 lines in total. Specifically, in this embodiment, the grounding wire 18 embedded in the substrate 31 is 5 lines, the dual-purpose signal wire 19 is 4 lines, and the rectifier ground wire (unnumbered) is 1 line. The number of grounding wires 18 is related to the number of column groups N of the electrode unit 33, which is greater than or equal to the number of column groups of the electrode unit 33, and N is a positive integer. The number of dual-purpose signal lines 19 is related to the number of row groups M of the electrode unit 33, which is greater than or equal to the number of row groups of the electrode unit 33, and M is a positive integer. The number of lines L embedded in the substrate 31 of the electrode sheet 13 is equal to the sum of the number of rectifier ground lines (not numbered), the number of ground lines 18, and the number of dual-purpose signal lines 19. In this embodiment, the number of ground lines 18 is equal to the number of column groups N of the electrode unit 33; the number of dual-purpose signal lines 19 is equal to the number of row groups M of the electrode unit 33.

[0085] The plurality of electrode units 33 are arranged on the substrate 31 in a two-dimensional array. Figure 2As shown, the electrode sheet 13 in this embodiment includes 20 electrode units 33, and the 20 electrode units 33 are arranged in an array of four rows and six columns. The first row and the fourth row each have four electrode units 33, and the second row and the third row each have six electrode units 33. The four electrode units 33 in each row of the first row and the fourth row are all located in each of the second to fifth columns, and the six electrode units 33 in each row of the second row and the third row are all located in each of the first to sixth columns. The five electrode units 33 located in the second and third columns of the first row and the first, second and third columns of the second row are divided into region 1, the five electrode units 33 located in the fourth and fifth columns of the first row and the fourth, fifth and sixth columns of the second row are divided into region 2, the five electrode units 33 located in the first, second and third columns of the third row and the second and third columns of the fourth row are divided into region 3, and the five electrode units 33 located in the fourth, fifth and sixth columns of the third row and the fourth and fifth columns of the fourth row are divided into region 4. Each area (1-4) corresponds to a row group. In some other embodiments, the 20 electrode units 33 may also be arranged in other ways. Of course, in some other embodiments, the electrode sheet 13 may also have other numbers of electrode units 33. In short, the implementation of the present application is not limited by the number and arrangement of the electrode units 33 of the electrode sheet 13.

[0086] Each electrode unit 33 can apply an alternating electric signal, and the electrode sheets 13 configured in pairs are used to apply an alternating electric field to the tumor site of the patient. Optionally, the electrode unit 33 includes a dielectric element, which can be a ceramic sheet or a polymer dielectric layer composed of a polymer material. Each temperature detection unit 35 is set corresponding to an electrode unit 33 to detect the temperature at the corresponding electrode unit 33. Each temperature detection unit 35 can be set at any position of the corresponding electrode unit 33, such as Figure 3 and Figure 4As shown, in this embodiment, each electrode unit 33 is provided with a through hole 331, and the through hole 331 is suitable for installing a temperature detection unit 35. For example, the middle of each electrode unit 33 has a through hole 331, and a corresponding temperature detection unit 35 is accommodated in the through hole 331 of each electrode unit 33. Each temperature detection unit 35 includes a temperature sensor 34, and the electrode sheet 13 is provided with a diode 36 corresponding to each temperature detection unit 35. The temperature sensor 34 has a signal terminal 34-2 and a ground terminal 34-1, and the diode 36 has an anode 36-1 and a cathode 36-2. The anode 36-1 of each diode 36 is connected to the ground terminal 34-1 of the corresponding temperature sensor 34, and the cathode 36-2 of the diode 36 corresponding to each column group is connected together and then connected to the ground pin GND through the corresponding control switch 54. Specifically, the anode 36-1 of the diode 36 is connected to the ground terminal 34-1 of the temperature sensor 34, the cathode 36-2 of the diode 36 is connected to the ground pin GND through the corresponding control switch 54, the ground terminal 34-1 of the temperature sensor 34 serves as the ground terminal 35-1 of the temperature detection unit 35, and the signal terminal 34-2 of the temperature sensor 34 serves as the signal terminal 35-2 of the temperature detection unit 35. The temperature sensor 34 can be a thermistor or other temperature sensors other than thermistors. Each temperature sensor 34 corresponds to a diode 36, which is connected in series with the temperature sensor 34 of the same electrode unit 33, and can prevent the reverse flow of current to prevent the detection signal from other electrode units 33 from affecting the temperature sensor 34.

[0087] like Figure 3As shown, the electrode sheet 13 of this embodiment includes 5 grounding wires 18, each of which is used to ground the grounding ends 35-1 of the temperature detection units 35 of the same column group. The 5 grounding wires 18 of the electrode sheet 13 are respectively a first grounding wire 18-1, a second grounding wire 18-2, a third grounding wire 18-3, a fourth grounding wire 18-4 and a fifth grounding wire 18-5. Among the five column groups of the electrode sheet 13, the first column group includes electrode unit 33-1, electrode unit 33-6, electrode unit 33-11, and electrode unit 33-16; the second column group includes electrode unit 33-2, electrode unit 33-7, electrode unit 33-12, and electrode unit 33-17; the third column group includes electrode unit 33-3, electrode unit 33-8, electrode unit 33-13, and electrode unit 33-18; the fourth column group includes electrode unit 33-4, electrode unit 33-9, electrode unit 33-14, and electrode unit 33-19; and the fifth column group includes electrode unit 33-5, electrode unit 33-10, electrode unit 33-15, and electrode unit 33-20.Specifically, the first grounding line 18-1 is used to ground the temperature detection units 35 corresponding to the electrode units 33-1, 33-6, 33-11, and 33-16 in the first column group; the second grounding line 18-2 is used to ground the two temperature detection units 35 connected in series between the electrode units 33-1 and 33-2, the two temperature detection units 35 connected in series between the electrode units 33-6 and 33-7, the two temperature detection units 35 connected in series between the electrode units 33-11 and 33-12, and the two temperature detection units 35 connected in series between the electrode units 33-16 and 33-17; the third grounding line 18-3 is used to ground the three temperature detection units 35 connected in series between the electrode units 33-1 to 33-3, the three temperature detection units 35 connected in series between the electrode units 33-6 to 33-8, and the three temperature detection units 35 connected in series between the electrode units 33-11 and 33-13. 5. The three temperature detection units 35 connected in series from electrode unit 33-16 to electrode unit 33-18 are grounded; the fourth grounding line 18-4 is used to ground the four temperature detection units 35 connected in series from electrode unit 33-1 to electrode unit 33-4, the four temperature detection units 35 connected in series from electrode unit 33-6 to electrode unit 33-9, the four temperature detection units 35 connected in series from electrode unit 33-11 to electrode unit 33-14, and the four temperature detection units 35 connected in series from electrode unit 33-16 to electrode unit 33-19; the fifth grounding line 18-5 is used to ground the five temperature detection units 35 connected in series from electrode unit 33-1 to electrode unit 33-5, the five temperature detection units 35 connected in series from electrode unit 33-6 to electrode unit 33-10, the five temperature detection units 35 connected in series from electrode unit 33-11 to electrode unit 33-15, and the five temperature detection units 35 connected in series from electrode unit 33-16 to electrode unit 33-20. It should be noted that these grounding wires 18 can be selectively closed or disconnected, for example, by connecting each grounding wire 18 in series with a control switch 54, that is, the grounding end 35-1 of the temperature detection unit 35 corresponding to each electrode unit 33 in each column group is connected to the ground pin GND through a control switch 54, which will be described in detail below. Figure 4 , after the grounding end 34-1 of the corresponding temperature sensor 34 in each column group is connected to the anode 36-1 of the corresponding diode 36, they are connected together through the cathode 36-2 of the corresponding diode 36. In short, each grounding line 18 short-circuits the grounding ends 35-1 of the temperature detection units 35 corresponding to all electrode units 33 in each column group through the diode 36 and grounds them.

[0088] like Figure 3As shown, the electrode sheet 13 of this embodiment also includes 4 dual-purpose signal lines 19, one end of each dual-purpose signal line 19 is respectively connected to the fixed end 3 of the rectifier switching unit 16 corresponding to each row group, and the other end is connected to the adapter 20 for receiving the temperature detection signal and transmitting the alternating electric signal. Specifically, the 4 dual-purpose signal lines 19 of the electrode sheet 13 include a first dual-purpose signal line 19-1, a second dual-purpose signal line 19-2, a third dual-purpose signal line 19-3 and a fourth dual-purpose signal line 19-4. The five electrode units 33 from electrode unit 33-1 to electrode unit 33-5 are respectively connected to the second switching end 2 of the corresponding rectifying switching unit 16, and the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-1 to electrode unit 33-5 are respectively connected in series and connected to the first switching end 1 of the corresponding rectifying switching unit 16; the five electrode units 33 from electrode unit 33-6 to electrode unit 33-10 are respectively connected to the second switching end 2 of the corresponding rectifying switching unit 16, and the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-6 to electrode unit 33-10 are respectively connected to the first switching end 1 of the corresponding rectifying switching unit 16; The five electrode units 33 from electrode unit 33-11 to electrode unit 33-15 are respectively connected to the second switching end 2 of the corresponding rectifying switching unit 16, and the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-11 to electrode unit 33-15 are connected in series and then connected to the first switching end 1 of the corresponding rectifying switching unit 16; the five electrode units 33 from electrode unit 33-16 to electrode unit 33-20 are respectively connected to the second switching end 2 of the corresponding rectifying switching unit 16, and the temperature detection units 35 corresponding to the five electrode units 33 from electrode unit 33-16 to electrode unit 33-20 are connected in series and then connected to the first switching end 1 of the corresponding rectifying switching unit 16. In short, each dual-purpose signal line 19 is respectively connected to each electrode unit 33 located in the same row group through the corresponding rectifying switching unit 16, and is connected in series to each temperature detection unit 35 corresponding to each electrode unit 33 located in the same row group. It should be noted that these dual-purpose signal lines 19 can selectively transmit alternating electrical signals or temperature detection electrical signals, which can be achieved by matching each dual-purpose signal line 19 with the corresponding rectification switching unit 16 and multiplexing switching unit.That is to say, each temperature detection unit 35 in each row group is connected in series to the corresponding rectification switching unit 16, and then connected to the multiplexing switching unit through a dual-purpose signal line 19. The multiplexing switching unit includes a plurality of bidirectional switches 55, such as a bidirectional switch 55-1, a bidirectional switch 55-2, a bidirectional switch 55-3, and a bidirectional switch 55-4. Each bidirectional switch 55 has a fixed end (unnumbered) electrically connected to the corresponding dual-purpose signal line 19, an end 1 (i.e., a temperature sampling point) electrically connected to the ADC unit 52 in the adapter 20, and an end 2 (i.e., a temperature sampling point) electrically connected to the alternating power line 57. The multiplexing switching unit is configured to switch the dual-purpose signal line 19 to be connected to the temperature sampling point (unnumbered) or the alternating power line 57, wherein any one of the dual-purpose signal lines 19 is connected to the corresponding temperature sampling point (unnumbered). ), the rectifier switching unit 16 corresponding to the dual-purpose signal line 19 is linked to make the first switching end 1 of the rectifier switching unit 16 corresponding to the dual-purpose signal line 19 connected to the fixed end 3, and the control switches 54 corresponding to each column group are configured to be closed in sequence, so that the analog temperature signals detected by each temperature detection unit 35 in the row group corresponding to the dual-purpose signal line 19 are sampled in sequence based on the corresponding temperature sampling points (unnumbered); when any one of the dual-purpose signal lines 19 is connected to the alternating power line 57, the rectifier switching unit 16 corresponding to the dual-purpose signal line 19 is linked to make the second switching end 2 of the rectifier switching unit 16 corresponding to the dual-purpose signal line 19 connected to the fixed end 3, so that each electrode unit 33 in the row group corresponding to the dual-purpose signal line 19 is applied with the alternating electrical signal based on the alternating power line 57.

[0089] The multi-channel grounding wire 18, the multi-channel dual-purpose signal wire 19 and the rectifier ground wire (not numbered) are all conductive traces embedded in the substrate 31. The substrate 31 is electrically connected to the first cable 15. The multi-channel grounding wire 18, the multi-channel dual-purpose signal wire 19 and the rectifier ground wire (not numbered) embedded in the substrate 31 are electrically connected to the corresponding wires (not shown) in the first cable 15 one by one.

[0090] The tumor electric field treatment system 100 of this embodiment includes at least one pair of the above-mentioned electrode sheets 13, an adapter 20 electrically connected to the electrode sheets 13, and an electric field generator 30 electrically connected to the adapter 20. The adapter 20 is connected between the electrode sheets 13 and the electric field generator 30. The electric field generator 30 provides an alternating electric signal to a plurality of electrode units 33 of the electrode sheet 13 via the adapter 20 and the dual-purpose signal line 19 of the electrode sheet 13, or is used to receive the temperature detection signal output by the temperature detection unit 35 corresponding to the plurality of electrode units 33. The adapter 20 transmits the alternating electric signal generated by the electric field generator 30 to the dual-purpose signal line 19 of the electrode sheet 13, and is also configured to receive the temperature detection signal output by the multiplex dual-purpose signal line 19 of the electrode sheet 13.

[0091] refer to Figure 3 As shown, the adapter 20 includes: a first controller 51, multiple groups of ADC units 52 connected to the first controller 51, multiple groups of piezoelectric resistors 53 and multiple groups of control switches 54 corresponding to the multiple groups of ADC units 52, multiple groups of bidirectional switching switches 55 corresponding to the multiple groups of ADC units 52, a first communication unit 56, an alternating power line 57 corresponding to each group of bidirectional switching switches 55, and a first power module 58 connected to the first communication unit 56, the first controller 51 and the multiple groups of ADC units 52, and the first power module 58 provides a DC power supply VCC for each electronic component of the adapter 20. The adapter 20 also includes multiple circuit lines (unnumbered), which are electrically connected to the multiple grounding lines 18, the multiplexed signal lines 19 and the rectifier ground line (unnumbered) in the substrate 31 of the electrode sheet 13 through the first cables 15 of the corresponding electrode sheet 13. The multiple circuit lines (unnumbered) include multiple alternating power lines 57 that transmit alternating electrical signals to the corresponding electrode sheets 13 and are electrically connected to the dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode sheets 13, multiple circuit lines (unnumbered) that are electrically connected one-to-one with the dual-purpose signal lines 19 in the substrate 31 of the corresponding electrode sheets 13 and are used to supply power to the temperature detection units 35 of the electrode sheets 13 or to transmit the temperature detection signals of the electrode sheets 13, multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple grounding lines 18 in the substrate 31 of the corresponding electrode sheets 13, and one circuit line that is electrically connected to the grounding lines of each rectifier switching unit 16. The number L of circuit lines electrically connected between the adapter 20 and one electrode sheet 13 is equal to the sum of the number of rows M and the number of columns N of the electrode units 33 of the electrode sheet 13 plus one; the number H of circuits electrically connected between the adapter 20 and X electrode sheets 13 is equal to X times the number of circuit lines electrically connected to a single electrode sheet 13, that is, H=XL=X*(M+N+1). The number of groups of control switches 54 and the number of groups of bidirectional switching switches are both related to the number of electrode sheets 13. The number of groups of control switches 54 is the same as the number of groups of bidirectional switching switches and is not less than the number of electrode sheets 13. Optionally, the number of groups of control switches 54 and bidirectional switching switches is the same as the number of electrode sheets 13. The following is a detailed description taking only the electrical connection between an electrode sheet 13 having 20 electrode units 33 and the adapter 20 as an example.

[0092] Each group of control switches 54 is provided with a plurality of control switches 54, which are respectively connected to the adapter 20 and are respectively electrically connected to circuit lines (unnumbered) corresponding one by one to the multi-way grounding lines 18 of a corresponding electrode sheet 13, and are configured to control the conduction or disconnection between the multi-way grounding lines 18 and the ground pin GND. The circuit lines (unnumbered) of the multi-way grounding lines 18 electrically connected one by one to the electrode sheet 13 are grounded at one end close to the control switch 54. The number of control switches 54 in each group of control switches 54 is related to the number of grounding lines 18 of the substrate 31 of the corresponding electrode sheet 13, and the two are equal in this embodiment. Figure 3 As shown, in this embodiment, the plurality of control switches 54 are respectively a first control switch 54-1, a second control switch 54-2, a third control switch 54-3, a fourth control switch 54-4 and a fifth control switch 54-5. The plurality of control switches 54 in the same group control the closing or opening of the corresponding grounding wire 18 of the same electrode sheet 13 one by one. The first control switch 54-1 is used to control the closing or disconnection of the first grounding line 18-1 of the corresponding electrode sheet 13, and can cooperate with the corresponding group of two-way switching switches 55 and the rectifying switching unit 16 to control the power on and off of each temperature detection unit 35 corresponding to the four electrode units 33 in the first column group of the electrode sheet 13, namely, the electrode unit 33-1, the electrode unit 33-6, the electrode unit 33-11, and the electrode unit 33-16; the second control switch 54-2 is used to control the closing or disconnection of the second grounding line 18-2 of the electrode sheet 13, and can cooperate with the corresponding group of two-way switching switches 55 and the rectifying switching unit 16 to control the multiple electrode units 33 in the first column group and the second column group of the electrode sheet 13 (the multiple electrode units 33 can be respectively: electrode unit 33-1 and electrode unit 33-2, electrode unit 33-6 and electrode unit 33-11, electrode unit 33-16, ... The third control switch 54-3 is used to control the closing or disconnection of the third grounding line 18-3 of the electrode sheet 13, and can cooperate with the corresponding group of bidirectional switching switches 55 and the rectifier switching unit 16 to control the power on and off of each temperature detection unit 35 corresponding to the plurality of electrode units 33 in the first column group, the second column group and the third column group of the electrode sheet 13 (the plurality of electrode units 33 can be respectively: electrode units 33-1 to 33-3, electrode units 33-6 to 33-8, electrode units 33-11 to 33-13, electrode units 33-16 to 33-18); the fourth control switch 54-4 and the fifth control switch 54-5 are the same. The above control switch 54 can be a mechanical switch, such as a relay. The control switch 54 may also be an electronic switch, and each control switch 54 may be switched on and off by an additional first controller 51 .

[0093] In this embodiment, the multiple groups of control switches 54 are all electronic switches. The first controller 51 is connected to the multiple groups of control switches 54 in communication, and is used to sequentially and cyclically control the opening and closing states of multiple control switches 54 in each group of control switches 54, and then sequentially and individually conduct each of the multiple grounding wires 18 of the corresponding electrode sheet 13 and cooperate with the switching of the corresponding bidirectional switch 55 and the rectifier switching unit 16 to collect the temperature of the patient's body surface detected by all temperature detection units 35 on the electrode sheet 13. The number of each group of control switches 54 is not less than the number of grounding wires 18 of the substrate 31 of the corresponding electrode sheet 13. In this embodiment, the number of each group of control switches 54 is the same as the number of grounding wires 18 of the corresponding electrode sheet 13.

[0094] Each multiplexing switching unit is provided with a plurality of bidirectional switching switches 55, which are respectively connected to the adapter 20 and are respectively electrically connected to the circuit lines (not numbered) corresponding to the multiplex dual-purpose signal lines 19 of the corresponding electrode sheet 13. The number of bidirectional switching switches 55 in each multiplexing switching unit is related to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13, which is greater than or equal to the number of dual-purpose signal lines 19 of the substrate 31 of the corresponding electrode sheet 13, and in this embodiment, the two are equal. Each bidirectional switch 55 has two ends marked as 1 and 2. End 1 of the multiple bidirectional switches 55 in the same group is the temperature sampling point, which is electrically connected one by one to the corresponding detection channels of the multiple detection channels of the corresponding group of ADC units 52. Both ends of each bidirectional switch 55 in the same group are electrically connected to the corresponding same alternating power line 57, and are configured to control the multi-channel dual-purpose signal line 19 to connect to the corresponding alternating power line 57 to transmit the alternating electrical signal or to connect to the corresponding detection channel of the corresponding group of ADC units 52 to receive the temperature detection signal output by the temperature detection unit 35.

[0095] like Figure 3As shown, taking an electrode sheet 13 electrically connected to the adapter 20 as an example, in this embodiment with 20 electrode units 33, the plurality of bidirectional switches 55 are respectively a first bidirectional switch 55-1, a second bidirectional switch 55-2, a third bidirectional switch 55-3 and a fourth bidirectional switch 55-4. The plurality of bidirectional switches 55 in the same group respectively control the switching between the transmission of the alternating electric signal and the transmission of the temperature detection signal of a corresponding one of the multiplexed dual-purpose signal lines 19 of the same electrode sheet 13. Specifically, the first bidirectional switch 55-1 is used to control the switching of the first dual-purpose signal line 19-1 of the corresponding electrode sheet 13 between transmitting the alternating electric signal and transmitting the temperature detection signal, and then cooperates with the rectifier switching unit 16 corresponding to the first row group of the electrode sheet 13 to control the conduction of each electrode unit 33 from the electrode unit 33-1 to the electrode unit 33-5 in the first row group, or the conduction of the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-1 to the electrode unit 33-5 in the first row group, and cooperates with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to enable the first row of electrode units 33-1 to the electrode unit 33-5 to transmit the alternating electric signal to the patient or enable the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to the electrode units 33 to be sampled and output to the corresponding ADC unit 52. The second bidirectional switch 55-2 is used to control the switching of the second dual-purpose signal line 19-2 of the corresponding electrode sheet 13 between transmitting the alternating electric signal and transmitting the temperature detection signal, and then cooperates with the rectifier switching unit 16 corresponding to the second row group of the electrode sheet 13 to control the conduction of each electrode unit 33 from the electrode unit 33-6 to the electrode unit 33-10 in the second row group, or conducts with the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-6 to the electrode unit 33-10 in the second row group, and cooperates with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to enable the second row electrode unit 33-6 to the electrode unit 33-10 to transmit the alternating electric signal to the patient or enable the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to the electrode units 33 to be sampled and output to the corresponding ADC unit 52;The third bidirectional switch 55-3 is used to control the switching of the third dual-purpose signal line 19-3 of the corresponding electrode sheet 13 between transmitting alternating electric signals and transmitting temperature detection signals, and then cooperates with the rectifier switching unit 16 corresponding to the third row group of the electrode sheet 13 to control the conduction of each electrode unit 33 from the electrode unit 33-11 to the electrode unit 33-15 in the third row group of the electrode sheet 13, or conducts with the signal end 35-2 of each temperature detection unit corresponding to the electrode unit 33-11 to the electrode unit 33-15 in the third row group, and cooperates with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to enable the third row of electrode units 33-11 to the electrode unit 33-15 to transmit alternating electric signals to the patient or enable the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to the electrode units 33 to be sampled and output to the corresponding ADC unit 52; The four bidirectional switching switches 55-4 are used to control the switching of the fourth dual-purpose signal line 19-4 of the corresponding electrode sheet 13 between transmitting alternating electrical signals and transmitting temperature detection signals, and then work together with the rectifier switching unit 16 corresponding to the fourth row group of the electrode sheet 13 to control the conduction of each electrode unit 33 from the electrode unit 33-16 to the electrode unit 33-20 in the fourth row group of the electrode sheet 13, or to conduct with the signal end 35-2 of each temperature detection unit 35 corresponding to the electrode unit 33-16 to the electrode unit 33-20 in the fourth row group, and cooperate with the corresponding control switch 54-1, control switch 54-2, control switch 54-3, control switch 54-4, and control switch 54-5 to enable the fourth row of electrode units 33-16 to the electrode unit 33-20 to transmit alternating electrical signals to the patient or enable the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 35 corresponding to the electrode units 33 to be sampled and output to the corresponding ADC unit 52. When two ends of each group of two-way switches are turned on and one end is turned off, and the second switching end 2 of the corresponding rectifying switching unit 16 is connected to the fixed end 3, an alternating electrical signal can be transmitted to each electrode unit 33 in the corresponding row group of the corresponding electrode sheet 13. When one end of each two-way switch 55 in each group of two-way switches 55 is turned on and two ends are turned off in sequence and in time-sharing, and two ends of the remaining two-way switches 55 are turned on and one end is turned off, and the first switching end 1 of the corresponding rectifying switching unit 16 is connected to the fixed end 3, it can cooperate with each control switch 54 in the corresponding group of control switches 54 to transmit the temperature detection signal collected by the temperature detection unit 35 of each electrode unit 33 on the electrode sheet 13 in time-sharing. The above-mentioned two-way switch 55 can be a mechanical switch, such as a relay. The two-way switch can also be an electronic switch, and each two-way switch 55 can be switched by the first controller 51 of the adapter 20. ;

[0096] In this embodiment, the plurality of sets of two-way switches 55 are all electronic switches. The first controller 51 is in communication connection with the plurality of sets of two-way switches 55, and is used to control the plurality of two-way switches 55 in each set of two-way switches 55 to switch between their respective ends 1 and 2, and to coordinate the closing or opening of the corresponding control switch 54, so as to continuously monitor the temperature of the patient's body surface detected by all the temperature detection units 35 on the electrode sheet 13 or transmit an alternating electrical signal to the patient.

[0097] In some embodiments of the present application, Figure 3 As shown, the rectifying switching unit 16 includes a rectifying circuit 161 and a controllable switch 162. The rectifying circuit 161 is, for example, a rectifying bridge, which is configured to rectify the alternating current provided by the alternating power line 57 and supply it to the controllable switch 162 when the dual-purpose signal line 19 is connected to the alternating power line 57, so that the rectifying switching unit 16 switches the second switching end to be connected to the fixed end.

[0098] Specifically, the rectifier circuit 161 has terminals 1-4, terminal 1 of the rectifier circuit 161 is connected to the dual-purpose signal line 19 corresponding to the corresponding row group electrode unit 33 and terminal 3 of the controllable switch 162, terminals 2 and 4 of the rectifier circuit 161 are used to provide power to the controllable switch 162, terminal 3 of the rectifier circuit 161 is connected to the ground pin GND through a rectifier ground line (unnumbered), multiple electrode units 33 in the same row group are connected in parallel to terminals 2 of the controllable switch 162, multiple temperature sensors 34 in the same row group are connected in series, and a signal terminal 34-2 at the end of each row group is electrically connected to terminal 1 of the controllable switch 162. As an example, the controllable switch 162 can be a relay, an electronic switch, etc.

[0099] Among them, the controllable switch 162 is a normally closed switch, that is, it is turned on at one end and connected to the temperature sensor 34 by default. The controllable switch 162 is linked with the corresponding two-way switching switch 55. When the corresponding two-way switching switch 55 is switched to its own one end, the controllable switch 162 is also switched to its own one end, and the temperature sensor 34 located in the same row group is connected to the corresponding dual-purpose signal line 19, the connection between the electrode unit 33 in the corresponding row group and the corresponding dual-purpose signal line 19 is disconnected, and the corresponding control switch 54 is opened and closed to obtain the analog temperature signal detected by the corresponding temperature sensor 34; when the corresponding two-way switching switch 55 is switched to its own two ends, the AC signal is rectified by the rectifying circuit 161 to provide power, which will trigger the controllable switch 162. The controllable switch 162 is also switched to its own two ends, and the electrode unit 33 located in the same row group is connected to the corresponding dual-purpose signal line 19, the connection between the temperature sensor 34 in the corresponding row group and the corresponding dual-purpose signal line 19 is disconnected, and all the control switches 54 are disconnected to transmit the AC signal to the electrode unit 33 of the corresponding row group.

[0100] In this embodiment, each group of ADC units 52 is electrically connected to one end of each of the plurality of bidirectional switches 55 in the corresponding multiplexing switching unit through a multi-channel circuit line (not numbered) in the adapter 20, and is configured to receive the temperature detection signal transmitted by the multiplexed signal line 19 of the corresponding electrode sheet 13, and convert the temperature detection signal from an analog signal to a digital temperature signal. Figure 3 As shown, each group of ADC units 52 includes 4 detection channels A, B, C, and D, which are the first detection channel A, the second detection channel B, the third detection channel C, and the fourth detection channel D. Each detection channel A, B, C, and D is used to connect a corresponding dual-purpose signal line 19 in the multiple dual-purpose signal lines 19 through a corresponding bidirectional switch 55. Specifically, the first detection channel A is connected to the first dual-purpose signal line 19-1 through one end of the first bidirectional switch 55-1, the second detection channel B is connected to the second dual-purpose signal line 19-2 through one end of the second bidirectional switch 55-2, the third detection channel C is connected to the third dual-purpose signal line 19-3 through one end of the third bidirectional switch 55-3, and the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4 through one end of the fourth bidirectional switch 55-4. Each detection channel A, B, C, and D is used to receive the temperature detection signal collected by the temperature detection unit 35 corresponding to the electrode unit 33 to which the corresponding dual-purpose signal line 19 is connected. In addition, each detection channel A, B, C, D is connected to a first power module 58 for providing a detection voltage to the detection channel A, B, C, D via a corresponding voltage divider resistor 53 in the adapter 20. The first power module 58 provides direct current.

[0101] In this embodiment, the first communication unit 56 is configured to obtain the digital temperature signals output by the multiple groups of ADC units 52, and send the digital temperature signals to the electric field generator 30. The electric field generator 30 is also configured to control and adjust the voltage of the alternating electric signal provided to the multiple electrode units 33 of the electrode sheet 13 according to the received digital temperature signal. Exemplarily, when any of the multiple digital temperature signals received exceeds the preset threshold, it means that the temperature detected by the temperature detection unit 35 corresponding to at least one electrode unit 33 in the electrode sheet 13 exceeds the preset temperature threshold (for example, 41°C, 42°C, etc.), and at this time, the voltage of the alternating electric signal output by the electric field generator 30 can be appropriately reduced to avoid the electrode unit 33 of the electrode sheet 13 from being too high in temperature when the alternating electric signal is applied, causing low-temperature burns to the patient's skin. The above-mentioned preset temperature threshold and preset threshold can be determined according to the human safety threshold. The first communication unit 56 is controlled by the first controller 51 and transmits the digital temperature signals converted by the multiple groups of ADC units 52 in series. In this embodiment, the preset temperature threshold can be a value within 36°C-45°C.

[0102] refer to Figure 5 and Figure 6 In this embodiment, the first power module 58 is electrically connected to the second power module 32 of the electric field generator 30, and is configured to supply power to the first controller 51, the multiple ADC units 52, and the first communication unit 56 of the adapter 20. A first connector 60 is connected between each electrode sheet 13 and the adapter 20, and the first connector 60 is suitable for connecting the corresponding electrode sheet 13 to the adapter 20. Figure 1 As shown, the first connector 60 includes a first plug 61 provided at one end of the first cable 15 away from the electrode sheet 13 and a first socket 62 provided on the adapter 20. The first plug 61 and the first socket 62 are push-type spring connectors, that is, the first connector 60 uses a connector to connect the adapter 20 with the electrode sheet 13. Each first cable 15 has four wires electrically connected to the two-way switch 55 in the corresponding group of two-way switches 55, five wires electrically connected to the control switch 54 in the corresponding group of control switches 54, and one grounding wire connected to the rectifier switching unit 16, that is, each first connector 60 is electrically connected to a corresponding group of two-way switch 55 and a corresponding group of control switches 54 and a corresponding grounding wire of the adapter 20 through 10 wires, and is connected to the electric field generator 30 through a corresponding alternating power line 57 of the adapter 20.

[0103] A second connector 70 is provided between the adapter 20 and the electric field generator 30, and the second connector 70 is suitable for connecting the electric field generator 30 to the adapter 20. Figure 1As shown, the adapter 20 also includes a second cable 25 connected to the second connector 70. The second connector 70 includes a second plug 71 provided at an end of the second cable 25 away from the first controller 51 and a second socket 72 provided on the electric field generator 30. The second plug 71 and the second socket 72 are push-type spring connectors, that is, the second connector 70 uses a connector to connect the adapter 20 to the electric field generator 30. Each first connector 60 such as X1, Y1, X2 and Y2 is connected to the second connector 70 through a corresponding alternating power line 57, and the first connector 60 such as X1, Y1, X2 and Y2 is also connected to a corresponding group of control switches 54 and a corresponding group of ADC units 52, wherein each first connector 60 is connected to the second connector 70 and a corresponding group of ADC units 52 through a corresponding group of bidirectional switching switches 55. The second cable 25 has 8 conductors, including 4 conductors 1 to 4 electrically connected to the corresponding alternating power lines 57 and used to transmit alternating electrical signals, a conductor 5 electrically connected to the data receiving line RX of the first communication unit 56, a conductor 6 electrically connected to the data sending line TX of the first communication unit 56, a conductor 7 electrically connected to the VCC power line of the first power module 58, and a conductor 8 electrically connected to the GND line of the first power module 58. The second connector 70 is connected to the first communication unit 56 through the data receiving line RX and the data sending line TX, the VCC pin of the second connector 70 is connected to the VVC power line of the first power module 58, the GND pin of the second connector 70 is connected to the GND line of the first power module 58 and grounded, and the VCC pin of the second connector 70 is also connected to the corresponding group of voltage dividers 53 and the corresponding group of ADC units 52 through the VCC power line of the first power module 58.

[0104] refer to Figure 5 and Figure 7The electric field generator 30 includes: a second power supply module 32, a second controller 37, an AC signal generator 39, a second communication unit 38 and a group of power switches 40. The VCC pin of the second connector 70 is also electrically connected to the VCC power line of the second power supply module 32, and the GND pin of the second connector 70 is grounded through the GND line of the second power supply module 32. The second power supply module 32 is also connected to the second controller 37 and the AC signal generator 39 respectively and supplies power to them. The second communication unit 38 is electrically connected to the wire 5 of the second connector 70 through its data receiving line RX and is electrically connected to the wire 6 of the second connector 70 through its data sending line TX, thereby realizing information interaction between the electric field generator 30 and the adapter 20. The second controller 37 is also electrically connected to the second communication unit 38, the AC signal generator 39 and a group of power switches 40. The second controller 37 is configured to control the opening and closing of each power switch 40 in the group of power switches 40 and adjust the relevant parameters of the alternating electric signal applied by the AC signal generator 39 according to the relevant digital temperature signal received by the second communication unit 38 from the adapter 20. The AC signal generator 39 is electrically connected to the wires 1 to 4 of the second connector 70 for transmitting the alternating electric signal through the group of power switches 40. The group of power switches 40 includes a plurality of power switches 40, and the plurality of power switches 40 are arranged in a one-to-one correspondence with the plurality of electrode sheets 13. Each power switch 40 is electrically connected to a corresponding wire 1, 2, 3, 4 for transmitting the alternating electric signal in the second connector 70 through an AC power line 41-1, 41-2, 41-3, 41-4 and is electrically connected to the corresponding electrode sheet 13 through the corresponding wires 1, 2, 3, 4 of the second connector 70, so as to transmit the alternating electric signal to each electrode sheet 13. The AC signal generator 39 is electrically connected to the group of power switches 40 through a plurality of AC power lines 41. Specifically, the number of power switches 40 of the electric field generator 30 is related to the number of electrode sheets 13. In this embodiment, the number of power switches 40 is equal to the number of electrode sheets 13 and both are 4. The power switches 40 include a first power switch 40-1, a second power switch 40-2, a third power switch 40-3, and a fourth power switch 40-4, which are electrically connected to the wires 1 to 4 of the second connector 70 in a one-to-one correspondence.One end of the first power switch 40-1 is electrically connected to the AC signal generator 39 through the AC power line (not numbered) of the electric field generator 30, and the other end is electrically connected to the corresponding wire 1 for transmitting alternating electric signals in the second connector 70 through an AC power line 41-1, and is electrically connected to the alternating power line 57 at the port X1 of the adapter 20 through the wire 1 of the second connector 70, the alternating power line 57 at the port X1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits the alternating electric signal to the electrode sheet 13 electrically connected to the port X1 of the adapter 20 One end of the second power switch 40-2 is electrically connected to the AC signal generator 39 through the AC power line (unnumbered) of the electric field generator 30, and the other end is electrically connected to the corresponding wire 2 for transmitting alternating electric signals in the second connector 70 through an AC power line 41-2, and is electrically connected to the alternating power line 57 at the port Y1 of the adapter 20 through the wire 2 of the second connector 70, the alternating power line 57 at the port Y1 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y1 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits an alternating electric signal to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20 One end of the third power switch 40-3 is electrically connected to the AC signal generator 39 through the AC power line (unnumbered) of the electric field generator 30, and the other end is electrically connected to the corresponding wire 3 for transmitting alternating electric signals in the second connector 70 through an AC power line 41-3, and is electrically connected to the alternating power line 57 at the port X2 of the adapter 20 through the wire 3 of the second connector 70, the alternating power line 57 at the port X2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port X2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits an alternating electric signal to the electrode sheet 13 electrically connected to the port X2 of the adapter 20 One end of the fourth power switch 40-4 is electrically connected to the AC signal generator 39 through the AC power line (unnumbered) of the electric field generator 30, and the other end is electrically connected to the corresponding conductor 4 for transmitting alternating electric signals in the second connector 70 through an AC power line 41-4 and is electrically connected to the alternating power line 57 at the port Y2 of the adapter 20 through the conductor 4 of the second connector 70, the alternating power line 57 at the port Y2 of the adapter 20 is electrically connected to the first connector 60, and the first connector 60 at the port Y2 of the adapter 20 is electrically connected to the corresponding electrode sheet 13, so as to control whether the AC signal generator 39 transmits an alternating electric signal to the electrode sheet 13 electrically connected to the port Y1 of the adapter 20.

[0105] The following will refer to Figures 3 to 5The working principle of the tumor electric field treatment system 100 of this embodiment is described in detail.

[0106] Specifically, when it is necessary to detect the temperature of each electrode unit 33 of a certain electrode sheet 13, the second controller 37 of the electric field generator 30 controls the corresponding power switch 40 to disconnect the alternating electric signal applied to the electrode sheet 13, and the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls one end of a plurality of bidirectional switches 55 of a multiplexing switching unit electrically connected to the electrode sheet 13 to be turned on and the other end to be turned off, and the corresponding temperature detection unit 35 is powered by the VCC provided by the first power module 58, and the rectifier switching unit linked to the bidirectional switch 55 is turned on. The contact 3 of the controllable switch 162 in 16 is connected to the contact 1; at the same time, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls each control switch 54 in a group of control switches 54 electrically connected to the electrode sheet 13 to be turned on in sequence in a time-sharing manner. At this time, the detection channel connected to one end of the bidirectional switch 55 in the multiple detection channels of the group of ADC units 52 corresponding to the electrode sheet 13 can sample the combined temperature detection signal detected by the first temperature detection unit 35 or multiple temperature detection units 35 in the corresponding row group in sequence, and the above temperature detection signal can be represented by a voltage value. Only one of the five control switches 54 in the group of control switches 54 corresponding to the electrode sheet 13 can be turned on at the same time, and the other four can be turned off. Only one of the four bidirectional switching switches 55 in the multiplexing switching unit corresponding to the group of ADC units 52 is switched to its end 1, and the rest are switched to their ends 2, so that one of the dual-purpose signal lines 19 of the electrode sheet 13 is electrically connected to a corresponding detection channel (A, B, C or D) of the ADC unit 52 and is turned on. With this arrangement, the group of ADC units 52 can collect the voltage value of the first temperature detection unit 35 in the same row group that is short-circuited with the ground line 18 corresponding to the turned-on control switch 54, or the voltage value of the first and second temperature detection units 35 in series, or the voltage value of the first to third temperature detection units 35 in series, or the voltage value of the first to fourth temperature detection units 35 in series, or the voltage value of the first to fifth temperature detection units 35 in series.

[0107] Further, when the first control switch 54-1 is closed, the second control switch 54-2, the third control switch 54-3, the fourth control switch 54-4 and the fifth control switch 54-5 are all opened, and the first bidirectional switch 55-1 is switched to its 1 end, the second bidirectional switch 55-2, the third bidirectional switch 55-3 and the fourth bidirectional switch 55-4 are all switched to their respective 2 ends, and the first switching end 1 of the rectifier switching unit 16 corresponding to the first row group is connected to the fixed end 3, the temperature detection unit 35 corresponding to the electrode unit 33-1 is powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off, and the signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A in the group of ADC units 52. Since only the power The signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is connected to the ground, while the ground ends 35-1 of the temperature detection units 35 corresponding to the electrode units 33-2, 33-3, 33-4 and 33-5 are disconnected, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, which will not affect the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-1. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-1 is effectively operated on the first detection channel A of the ADC unit 52, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-1, thereby realizing accurate temperature detection at the electrode unit 33-1.

[0108] When the second control switch 54-2 is closed, the first control switch 54-1, the third control switch 54-3, the fourth control switch 54-4 and the fifth control switch 54-5 are all disconnected, and the first bidirectional switch 55-1 is switched to its 1 end, the second bidirectional switch 55-2, the third bidirectional switch 55-3 and the fourth bidirectional switch 55-4 are all switched to their respective 2 ends, and the first switching end 1 of the rectifier switching unit 16 corresponding to the first row group is connected to the fixed end 3, the electrode unit 33-1 and the temperature detection unit 35 corresponding to the electrode unit 33-2 are connected in series and powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off, and the signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A in the group of ADC units 52, and the temperature detection units 35 corresponding to the electrode unit 33-1 and the electrode unit 33-2 are connected in series. Since only the temperature detection unit 35 corresponding to the electrode unit 33-2 The ground terminal 35-1 is connected to the ground, while the ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-3, 33-4 and 33-5 are disconnected, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, which will not affect the resistance of the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2. Therefore, only the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2 are effectively operated on the first detection channel A of the group of ADC units 52. The temperature detection signal (voltage value) collected by the first detection channel A is the sum of the voltage values ​​of the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2. The voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-1 is subtracted to obtain the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-2, thereby realizing accurate temperature detection at the electrode unit 33-2.

[0109] Similarly, when the third control switch 54-3 is closed, the first control switch 54-1, the second control switch 54-2, the fourth control switch 54-4 and the fifth control switch 54-5 are all disconnected, and the first bidirectional switching switch 55-1 is switched to its 1 end, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3 and the fourth bidirectional switching switch 55-4 are all switched to their respective 2 ends, and the first switching end 1 of the rectifier switching unit 16 corresponding to the first row group is connected to the fixed end 3, what is detected on the first detection channel A of the group of ADC units 52 is the sum of the voltage values ​​of the electrode unit 33-1, the electrode unit 33-2 and the temperature detection unit 35 corresponding to the electrode unit 33-3. By subtracting the sum of the voltage values ​​of the temperature detection unit 35 corresponding to the aforementioned electrode unit 33-1 and the electrode unit 33-2, the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-3 can be obtained, thereby realizing accurate detection of the temperature at the electrode unit 33-3.

[0110] By analogy, when the fourth control switch 54-4 is closed, the first control switch 54-1, the second control switch 54-2, the third control switch 54-3 and the fifth control switch 54-5 are all opened, and the first bidirectional switch 55-1 is switched to its 1 end, the second bidirectional switch 55-2, the third bidirectional switch 55-3 and the fourth bidirectional switch 55-4 are all switched to their respective 2 ends, and the first switching end 1 of the rectifier switching unit 16 corresponding to the first row group is connected to the fixed end 3, the temperature at the electrode unit 33-4 can be accurately controlled. Detection; when the fifth control switch 54-5 is closed, the first control switch 54-1, the second control switch 54-2, the third control switch 54-3 and the fourth control switch 54-4 are all disconnected, and the first bidirectional switching switch 55-1 is switched to its 1 end, the second bidirectional switching switch 55-2, the third bidirectional switching switch 55-3 and the fourth bidirectional switching switch 55-4 are all switched to their respective 2 ends, and the first switching end 1 of the rectifier switching unit 16 corresponding to the first row group is connected to the fixed end 3, accurate detection of the temperature at the electrode unit 33-5 can be achieved.

[0111] Thus, the temperature detection signals at the respective electrode units 33 in the first row group can be collected in sequence through the first detection channel A.

[0112] Similarly, when the first control switch 54-1 is closed, the second control switch 54-2, the third control switch 54-3, the fourth control switch 54-4 and the fifth control switch 54-5 are all opened, and the second bidirectional switch 55-2 is switched to its 1 end, the first bidirectional switch 55-1, the third bidirectional switch 55-3 and the fourth bidirectional switch 55-4 are all switched to their respective 2 ends, and the first switching end 1 of the rectifier switching unit 16 corresponding to the second row group is connected to the fixed end 3, the temperature detection unit 35 corresponding to the electrode unit 33-6 is powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off, and the signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is short-circuited on the second detection channel B in the group of ADC units 52. Since only the electrode unit 33-6 is powered on, the temperature detection unit 35 corresponding to the electrode unit 33-6 is powered on. The ground terminal 35-1 of the temperature detection unit 35 corresponding to the unit 33-6 is connected to the ground, while the ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-7, 33-8, 33-9 and 33-10 are disconnected, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, which will not affect the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-6. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-6 is effectively operated on the second detection channel B of the ADC unit 52 group, and the temperature detection signal (voltage value) collected by the second detection channel B is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-6, thereby realizing accurate temperature detection at the electrode unit 33-6.

[0113] When the second control switch 54-2 is closed, the first control switch 54-1, the third control switch 54-3, the fourth control switch 54-4 and the fifth control switch 54-5 are all disconnected, and the second bidirectional switch 55-2 is switched to its 1 end, the first bidirectional switch 55-1, the third bidirectional switch 55-3 and the fourth bidirectional switch 55-4 are all switched to their respective 2 ends, and the first switching end 1 of the rectifier switching unit 16 corresponding to the second row group is connected to the fixed end 3, the electrode unit 33-6 and the temperature detection unit 35 corresponding to the electrode unit 33-7 are connected in series and powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off, and the signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is short-circuited on the second detection channel B in the group of ADC units 52, and the temperature detection units 35 corresponding to the electrode unit 33-6 and the electrode unit 33-7 are connected in series. Since only the temperature detection unit 35 corresponding to the electrode unit 33-7 is The ground terminal 35-1 is connected to the ground, while the ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-8, 33-9 and 33-10 are disconnected, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, which will not affect the resistance value of the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7. Therefore, only the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7 on the second detection channel B of the group of ADC units 52 are effectively operated. The temperature detection signal (voltage value) collected by the second detection channel B is the sum of the voltage values ​​of the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7. The voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-6 is subtracted to obtain the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-7, thereby realizing accurate temperature detection at the electrode unit 33-7.

[0114] By analogy, the temperature signals at each electrode unit 33 in the second row group can be collected in sequence through the second detection channel B, the temperature signals at each electrode unit 33 in the third row group can be collected in sequence through the third detection channel C, and the temperature signals at each electrode unit 33 in the fourth row group can be collected in sequence through the fourth detection channel D.

[0115] Thus, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can collect the temperature detection signals of the temperature detection units 35 corresponding to all the electrode units 33 of a certain electrode sheet 13 by controlling a group of bidirectional switching switches 55 and a group of control switches 54 that are electrically connected to the electrode sheet 13. Similarly, the temperature detection signals of the temperature sensors 34 of the electrode units 33 of other electrode sheets 13 can be obtained.

[0116] The first controller 51 or the second controller 37, the multiple groups of ADC units 52 and the multiple groups of bidirectional switches 55 can automatically perform operations through pre-programmed program codes. For example, the first controller 51 or the second controller 37 first controls a bidirectional switch 55 in the corresponding group of bidirectional switches 55 to switch to end 1 so that end 1 of the bidirectional switch 55 is turned on and end 2 is turned off so that the corresponding dual-purpose signal line 19 of the corresponding electrode sheet 13 is electrically connected to the corresponding group of ADC units 52, and the first switching end 1 of the rectifier switching unit 16 linked to the bidirectional switch is connected to the fixed end, and then the control switch 54-1 in the corresponding group of control switches 54 is closed, and the remaining control switches 54-2 to 54-5 in the group of control switches 54 are turned off. During this period, the ADC units 52 in the corresponding group of control switches 54 are turned off. The corresponding detection channel of ADC unit 52 obtains the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33 located in the corresponding row group in the corresponding electrode sheet 13 and converts it into a digital temperature signal and stores it in a separately set memory. Then, after a preset interval, the first controller 51 or the second controller 37 closes the second control switch 54-2 in the group of control switches 54 and disconnects the first control switch 54-1, the third control switch 54-3, the fourth control switch 54-4, and the fifth control switch 54-5 in the group of control switches 54. During this period, the corresponding detection channel of the group of ADC units 52 obtains the temperature detection signals of the two temperature detection units 35 connected in series, and subtracts the previously obtained temperature detection signal to obtain the temperature detection signal corresponding to the current electrode unit 33. In this way, each control switch 54 in the group of control switches 54 is turned on separately in turn, and the temperature detection signals of all the temperature detection units 35 on the electrode sheet 13 can be obtained. Similarly, the temperature detection signals of all the temperature detection units 35 on at least one pair of electrode sheets 13 are obtained through this operation.

[0117] It should be noted that, in some other embodiments, the multiplexing switching unit is further configured to, when the control switch 54 corresponding to any column group is closed, switch the target dual-purpose signal line 19 to connect to the corresponding temperature sampling point, and link it through the rectifier switching unit 16 corresponding to the target dual-purpose signal line 19, so that the first switching end 1 of the rectifier switching unit 16 corresponding to the target dual-purpose signal line 19 is connected to the fixed end 3, so that the analog temperature signals detected by the corresponding temperature detection units 35 in the column group are sampled respectively.

[0118] Specifically, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can also control one of the control switches 54 electrically connected to a certain electrode sheet 13 to be closed, and at the same time control each bidirectional switching switch 55 in the multiplexing switching unit to turn on one end in turn, so that the detection channels A, B, C, and D in the group of ADC units 52 can be sampled in turn to obtain the temperature detection signals at each electrode unit 33 in the same column group.

[0119] For example, the first control switch 54-1 may be controlled to be closed, and the second control switch 54-2, the third control switch 54-3, the fourth control switch 54-4 and the fifth control switch 54-5 may be controlled to be opened. Then, when only the first bidirectional switch 55-1 is switched to its 1 end, the second bidirectional switch 55-2, the third bidirectional switch 55-3 and the fourth bidirectional switch 55-4 are all switched to their respective 2 ends, and the first switching end 1 of the rectifier switching unit 16 corresponding to the first row group is connected to the fixed end 3, the temperature detection unit 35 corresponding to the electrode unit 33-1 is powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off, and the signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A in the group of ADC units 52. Only the ground terminal 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is connected to the ground, while the ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-2, 33-3, 33-4 and 33-5 are disconnected, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, which will not affect the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-1. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-1 is effectively operated on the first detection channel A of the ADC unit 52 group, and the temperature detection signal (voltage value) collected by the first detection channel A is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-1, thereby realizing accurate temperature detection at the electrode unit 33-1.

[0120] When only the second bidirectional switch 55-2 is switched to its 1 end, the first bidirectional switch 55-1, the third bidirectional switch 55-3 and the fourth bidirectional switch 55-4 are all switched to their respective 2 ends, and the first switching end 1 of the rectifier switching unit 16 corresponding to the second row group is connected to the fixed end 3, the temperature detection unit 35 corresponding to the electrode unit 33-6 is powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off, and the signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is short-circuited on the second detection channel B in the group of ADC units 52. Since only the ground end 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is connected to the ground, The ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-7, 33-8, 33-9 and 33-10 are all disconnected, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, which will not affect the resistance value of the temperature detection unit 35 corresponding to the electrode unit 33-6. Therefore, only the temperature detection unit 35 corresponding to the electrode unit 33-6 is effectively operated on the second detection channel B of the ADC unit 52 group, and the temperature detection signal (voltage value) collected by the second detection channel B is the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-6, thereby realizing accurate temperature detection at the electrode unit 33-6.

[0121] By analogy, the temperature detection signals of the electrode units 33 of the first column group can be collected in sequence through the detection channels A, B, C, and D in the group of ADC units 52 .

[0122] Next, the second control switch 54-2 may be controlled to be closed, and the first control switch 54-1, the third control switch 54-3, the fourth control switch 54-4 and the fifth control switch 54-5 may be opened. Then, when only the first bidirectional switch 55-1 is switched to its 1 end, the second bidirectional switch 55-2, the third bidirectional switch 55-3 and the fourth bidirectional switch 55-4 are all switched to their respective 2 ends, and the first switching end 1 of the rectifier switching unit 16 corresponding to the first row group is connected to the fixed end 3, the temperature detection units 35 corresponding to the electrode unit 33-1 and the electrode unit 33-2 are connected in series and powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off, and the signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-1 is short-circuited on the first detection channel A in the group of ADC units 52, and the temperature detection units 35 corresponding to the electrode unit 33-1 and the electrode unit 33-2 are connected in series. Since only the temperature detection units 35 corresponding to the electrode unit 33-2 The ground terminal 35-1 of the unit 35 is connected to the ground, while the ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-3, 33-4 and 33-5 are disconnected, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, which will not affect the resistance of the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2. Therefore, only the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2 are effectively operated on the first detection channel A of the group of ADC units 52. The temperature detection signal (voltage value) collected by the first detection channel A is the sum of the voltage values ​​of the temperature detection units 35 corresponding to the electrode units 33-1 and 33-2. The voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-1 is subtracted to obtain the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-2, thereby realizing accurate temperature detection at the electrode unit 33-2.

[0123] Similarly, when only the second bidirectional switch 55-2 is switched to its 1 end, the first bidirectional switch 55-1, the third bidirectional switch 55-3 and the fourth bidirectional switch 55-4 are all switched to their respective 2 ends, and the first switching end 1 of the rectifier switching unit 16 corresponding to the second row group is connected to the fixed end 3, the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7 are connected in series and powered on, and the temperature detection units 35 corresponding to the remaining electrode units 33 are powered off, and the signal end 35-2 of the temperature detection unit 35 corresponding to the electrode unit 33-6 is short-circuited on the second detection channel B in the group of ADC units 52, and the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7 are connected in series. Since only the ground end 35-1 of the temperature detection unit 35 corresponding to the electrode unit 33-7 is turned on and grounded, while the electrode units 33-8 and 33-7 are connected in series, the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7 are connected in series. -9. The ground terminals 35-1 of the temperature detection units 35 corresponding to the electrode units 33-10 are disconnected, and each temperature detection unit 35 (including the temperature sensor 34) is connected in series with the corresponding diode 36, which will not affect the resistance values ​​of the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7. Therefore, only the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7 are effectively operated on the second detection channel B of the ADC unit 52. The temperature detection signal (voltage value) collected by the second detection channel B is the sum of the voltage values ​​of the temperature detection units 35 corresponding to the electrode units 33-6 and 33-7. The voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-6 is subtracted from the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-6, so as to obtain the voltage value of the temperature detection unit 35 corresponding to the electrode unit 33-7, thereby realizing accurate temperature detection at the electrode unit 33-7.

[0124] By analogy, the temperature detection signals of the electrode units 33 of the second column group can be collected in sequence through the detection channels A, B, C, and D in the group of ADC units 52 .

[0125] Similarly, the temperature detection signals of the electrode units 33 of the third column group, the fourth column group and the fifth column group can be sampled one by one based on the above method.

[0126] Therefore, in the embodiment of the present application, by controlling the switch 54, the bidirectional switching switch 55 and the controllable switch 162 in the rectifier switching unit 16, the temperature detection at each electrode unit 33 can be achieved without mutual interference and with high detection accuracy.

[0127] Specifically, when it is necessary to apply an alternating electric signal to each electrode unit 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the two ends of each of the multiple bidirectional switching switches 55 of the multiplexing switching unit electrically connected to the electrode sheet 13 to be turned on and one end to be turned off, and at the same time, the second switching end 2 of the corresponding rectifying switching unit 16 is connected to the fixed end 3, and a power supply switch 40 electrically connected to the electrode sheet 13 is controlled to be turned on. At this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply an alternating electric signal to each electrode unit 33 of the electrode sheet 13 through the alternating power line 57, and the voltage or current of the applied alternating electric signal is adjustable. That is, the multiplexing switching unit is also configured to switch the multi-channel target dual-purpose signal line 19 to be connected to the alternating power line 57, and to be linked through the rectifying switching unit 16 corresponding to the multi-channel target dual-purpose signal line 19, so that the second switching end 2 of the rectifying switching unit 16 corresponding to the multi-channel target dual-purpose signal line 19 is connected to the fixed end 3, so that each electrode unit 33 in the row group corresponding to the multi-channel target dual-purpose signal line 19 is simultaneously applied with the alternating electrical signal based on the alternating power line 57.

[0128] It should be noted that, in other embodiments, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 can also control a group of bidirectional switches 55 electrically connected to a certain electrode sheet 13 to apply an alternating electric signal to some electrode units 33 of the electrode sheet 13 in the same time period. For example, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the first bidirectional switch 55-1 of the plurality of bidirectional switches 55 of the group of bidirectional switches 55 electrically connected to the electrode sheet 13 to turn on two ends and turn off one end, the second switching end 2 of the rectifier switching unit 16 linked thereto is connected to the fixed end 3, and controls a power supply switch 40 electrically connected to the electrode sheet 13 to turn on, at this time, the second controller 37 of the electric field generator 30 controls the AC signal generator 39 to apply an alternating electric signal to the first row group electrode units 33-1 to electrode units 33-5 of the electrode sheet 13 through the alternating power line 57, and the voltage or current of the applied alternating electric signal is adjustable. That is, the multiplexing switching unit is configured to switch the dual-purpose signal line 19 corresponding to each row group to be connected to the alternating power line 57, so that the electrode units 33 of each row group are simultaneously applied with an alternating electrical signal based on the alternating power line 57. It should be noted that in other embodiments, the alternating electrical signal can also be simultaneously applied to the electrode units 33 of two or three row groups in the same time period, which will not be described in detail here.

[0129] It should be noted that the control switch 54 electrically connected to the multi-way grounding wires 18 of the electrode sheet 13 and the bidirectional switch 55 electrically connected to the multi-way dual-purpose signal wires 19 of the electrode sheet 13 in the embodiment of the present application are both provided in the adapter 20, but in other embodiments, the control switch 54 electrically connected to the grounding wire 18 and the bidirectional switch 55 electrically connected to the dual-purpose signal wire 19 can also be provided on the electrode sheet 13 or provided in the electric field generator 30, which will not be described in detail here. In addition, the ADC unit 52 provided in the adapter 20 can also be provided in the electric field generator 30 and directly controlled by the second controller 37.

[0130] The tumor electric field therapy system 100 of the present application can realize real-time, comprehensive and accurate monitoring of the temperature of all electrode units 33 on the electrode sheet 13 without increasing the weight of the electrode sheet 13 and without adding the core of the first cable 15 electrically connected to the electrode sheet 13, and then determine whether the electrode sheet 13 is qualified according to the obtained temperature detection signal; or determine whether the temperature detection unit 35 of the electrode sheet 13 is faulty or abnormal according to the obtained temperature detection signal, and determine whether the electrode sheet 13 needs to be replaced based on the number of faulty or abnormal temperature detection units 35 obtained; or identify the type of the electrode sheet according to the obtained temperature detection signal when the electrode sheet is qualified; or determine whether the electrode unit 33 of the electrode sheet 13 is over-temperature according to the obtained temperature detection signal when the electrode sheet is qualified, and then control the alternating electric signal applied to the electrode sheet 13 or the electrode unit 33 of the corresponding row of the electrode sheet 13 to avoid low-temperature burns on the patient's body surface when the tumor is treated by the electrode sheet 13. In addition, the substrate 31 of the electrode sheet 13 of the present application can transmit both alternating electrical signals and direct current signals for temperature signal collection through the dual-purpose signal line 19, and the two functions are completely isolated through the multiplexing switching unit and the rectifying switching unit 16, which not only greatly reduces the number of conductive traces (grounding line 18, dual-purpose signal line 19) arranged thereon, reduces the wiring difficulty of the substrate 31, simplifies the manufacturing process, reduces the weight of the substrate 31, and reduces the manufacturing cost. The electrode sheet 13 of the present application can also realize effective switching between applying alternating electrical signals for tumor treatment and transmitting direct current signals for temperature collection and transmitting the temperature detection signals obtained by collection through the combined control of the control switch 54 electrically connected to the grounding line 18 arranged thereon, the bidirectional switching switch 55 electrically connected to the dual-purpose signal line 19, and the rectifying switching unit 16.

[0131] Specifically, when it is necessary to apply an alternating electric signal to the patient through the electrode units 33 of a certain electrode sheet 13, the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls to disconnect all the control switches 54 in a group of control switches 54 corresponding to the electrode sheet 13, and at the same time controls to switch all the bidirectional switching switches 55 in a group of bidirectional switching switches 55 corresponding to the electrode sheet 13 to their respective two ends, so that one end of the bidirectional switching switches 55 is all disconnected and the two ends are all turned on, so that all the dual-purpose signal lines 19 of the electrode sheet 13 are electrically connected to the adapter 20 and an alternating power line 57 corresponding to the electrode sheet 13, and based on the linkage of each rectifier switching unit 16, the alternating electric signal is transmitted to each electrode unit 33 of the electrode sheet 13. When the digital temperature signal obtained by converting the temperature detection signal of the temperature detection unit 35 corresponding to all the electrode units 33 of the detected electrode sheet 13 is much lower than the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 controls the AC signal generator 39 through its second controller 37 to continue to generate an alternating electric signal with an increased voltage or current amplitude, or a constant voltage or current amplitude, and then transmits it to the corresponding pair of electrode sheets 13 through an alternating power line 57 corresponding to the adapter 20, so that the pair of electrode sheets 13 continue to apply the alternating electric signal; when the digital temperature signal obtained by converting the temperature detection signal of the temperature detection unit 35 corresponding to all the electrode units 33 of the detected electrode sheet 13 is lower than but close to the preset temperature threshold stored in the electric field generator 30 or the adapter 20, the electric field generator 30 can reduce the alternating electric signal generated by the AC signal generator 39 through the second controller 37. The voltage or current of the signal is reduced, thereby reducing the voltage or current of the alternating electric signal applied to the pair of electrode sheets 13; when it is detected that a digital temperature signal obtained by converting the temperature detection signal of the temperature detection unit 35 corresponding to an electrode unit 33 in a certain electrode sheet 13 is greater than a preset temperature threshold, the electric field generator 30 controls the power supply switch 40 electrically connected to the electrode sheet 13 to be disconnected through the second controller 37 to stop applying the alternating electric signal to the electrode sheet 13; or the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 controls all the two-way switching switches 55 in a group of two-way switching switches 55 electrically connected to the electrode sheet 13 to switch from their two ends to one end, that is, control all the one ends of all the two-way switching switches 55 in a group of two-way switching switches 55 electrically connected to the electrode sheet 13 to be turned on and all the two ends to be turned off, thereby stopping applying the alternating electric signal to the electrode sheet 13;Or, when it is detected that a digital temperature signal obtained by converting the temperature detection signal of the temperature detection unit 35 corresponding to an electrode unit 33 of a certain electrode sheet 13 is greater than a preset temperature threshold, the second controller 37 of the electric field generator 30 controls the power switch 40 electrically connected to the electrode sheet 13 to continue to be turned on, and the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 controls a bidirectional switch 55 electrically connected to the electrode unit 33 of the electrode sheet 13 to switch from its 2nd end to its 1st end, and the second controller 37 of the electric field generator 30 or the first controller 51 of the adapter 20 simultaneously controls the bidirectional switch 55 electrically connected to the electrode unit 33 of the electrode sheet 13 to switch from its 2nd end to its 1st end. The remaining two-way switching switches 55 electrically connected to the electrode units 33 in different rows from the electrode units 33 whose digital temperature signals obtained by temperature detection signal conversion do not exceed the preset temperature threshold and whose digital temperature signals obtained by temperature detection signal conversion exceed the preset temperature threshold continue to be electrically connected to their respective two ends, so as to stop applying alternating electric signals to all electrode units 33 in the row where the electrode units 33 whose digital temperature signals obtained by temperature detection signal conversion exceed the preset temperature threshold are located, and continue to apply alternating electric signals to the electrode units 33 in the remaining rows where the digital temperature signals obtained by temperature detection signal conversion do not exceed the preset temperature threshold. In this way, the control method for applying alternating electric signals based on temperature detection signals of the tumor electric field treatment system 100 is realized, and the operation of the tumor electric field treatment system 100 is reliably and efficiently controlled to improve the treatment effect. ;

[0132] The present application embodiment provides an electrode sheet temperature detection method, which is applied to the above-mentioned electrode sheet 13 or tumor electric field treatment system 100, referring to Figure 8 As shown, it includes the following steps:

[0133] Step 210: Control the multiplexing switching unit so that the dual-purpose signal line 19 corresponding to any row group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point, wherein the first switching end 1 of the rectifier switching unit 16 corresponding to the row group in the corresponding electrode sheet 13 is connected to the fixed end 3.

[0134] Specifically, the power supply switch 40, the bidirectional switching switch 55 electrically connected to the electrode units 33 of the electrode sheet 13, and the rectifying switching unit 16 are controlled to disconnect the alternating electric signal applied to the electrode units 33 of the electrode sheet 13, and at the same time connect the direct current signal applied to the signal terminal 35-2 of the temperature detection unit 35 of the electrode unit 33 of the electrode sheet 13.

[0135] Further, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled to switch from one end electrically connected to the alternating electric signal to one end electrically connected to the direct electric signal, that is, the bidirectional switching switch 55 electrically connected to the electrode sheet 13 is controlled to switch from its 2nd end to its 1st end, and at the same time, the rectifying switching unit 16 is switched from the second switching end 2 to the first switching end 1 and connected to the fixed end 3; or, the bidirectional switching switch 55 electrically connected to each electrode unit 33 of the electrode sheet 13 is controlled so that the electrode unit 33 of each electrode unit 33 of the electrode sheet 13 switches from the on state to the off state, and at the same time, the signal end 35-2 of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13 switches from the off state to the on state.

[0136] Step 220: Control the control switch 54 corresponding to each column group to sample the analog temperature signal of the corresponding electrode unit based on the corresponding temperature sampling point.

[0137] Specifically, the control switch 54 electrically connected to the ground terminal 35 - 1 of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13 is turned on in a time-sequential manner to obtain the temperature detection signal of the temperature detection unit 35 of each electrode unit 33 of the electrode sheet 13 .

[0138] In some embodiments, controlling the control switch 54 corresponding to each column group includes:

[0139] The control switches 54 corresponding to each column group are controlled to be closed in sequence, so as to sample the analog temperature signals detected by the temperature detection units 35 in the row group in sequence based on the corresponding temperature sampling points.

[0140] In some other embodiments, when the control switch 54 corresponding to any one of the column groups is closed, the method further includes:

[0141] The multiplexing switching unit is controlled so that the dual-purpose signal lines 19 corresponding to each row group in the corresponding electrode sheet 13 are connected to the corresponding temperature sampling points in sequence, so that the analog temperature signals detected by each temperature detection unit 35 in the column group are sampled respectively based on the corresponding temperature sampling points.

[0142] By adopting the temperature detection method of the electrode sheet 13 of the present application, the temperature of all the electrode units 35 of the electrode sheet 13 can be obtained quickly and accurately; and based on the obtained temperature detection signals of all the temperature detection units 35 of the electrode sheet 13, it can be judged whether the temperature detection units 35 of the electrode sheet 13 are faulty, whether there is an abnormality, or whether the electrode sheet 13 is qualified or needs to be replaced; it is also possible to judge whether each electrode unit 33 of the electrode sheet 13 is over-temperature based on the obtained temperature detection signals of all the temperature detection units 35 of the electrode sheet 13 when each temperature detection unit 35 of the electrode sheet 13 is normal, and then control the alternating electric signal applied to the electrode sheet 13 or to each electrode unit 33 of the electrode sheet 13 to improve the treatment effect; it is also possible to identify the type of electrode sheet when there is no abnormality in the temperature detection signals of each temperature detection unit 35 of the electrode sheet 13.

[0143] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of the embodiment of the present application is provided with a preset threshold, a first preset temperature, a second preset temperature and a preset temperature threshold, wherein the first preset temperature is lower than the second preset temperature, and the second preset temperature is lower than the preset temperature threshold.

[0144] Reference Fig. 9 As shown, the present application also provides a method for detecting abnormal temperature of an electrode sheet, which comprises the following steps:

[0145] Step 210: Control the multiplexing switching unit so that the dual-purpose signal line 19 corresponding to any row group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point, wherein the first switching end 1 of the rectifier switching unit 16 corresponding to the row group in the corresponding electrode sheet 13 is connected to the fixed end 3.

[0146] Step 220 : Control the control switch 54 corresponding to each column group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point to determine the temperature detection signal of each electrode unit 33 in each electrode sheet 13 .

[0147] Step 230: Determine whether the electrode sheet 13 is abnormal according to the temperature detection signal.

[0148] In some embodiments, determining whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0149] Step 231: Compare the temperature of each electrode unit 33 in the corresponding electrode sheet 13 with a preset temperature threshold according to the temperature detection signal. Specifically, the digital temperature signal corresponding to the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 can be compared with the preset temperature threshold.

[0150] Step 232: Determine whether the temperature of the electrode sheet 13 is abnormal based on the comparison result. Specifically, determine whether the temperature of each electrode unit 33 in the electrode sheet 13 is abnormal based on the comparison result.

[0151] The comparison result in step 232 includes not exceeding the preset temperature threshold and exceeding the preset temperature threshold. Not exceeding the preset temperature threshold includes being far below the preset temperature threshold and being close to the preset temperature threshold. The preset temperature threshold is 40°C-42°C. Optionally, the preset temperature threshold is 40.5°C-41.5°C. Optionally, the preset temperature threshold is 41°C-41.5°C. Optionally, the preset temperature threshold is 41°C.

[0152] The process of judging whether the temperature of the electrode sheet 13 is abnormal according to the comparison result in step 232 is specifically as follows: when the temperature of any electrode unit 33 in the corresponding electrode sheet 13 exceeds the preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is abnormal. When the temperature of all electrode units 33 in the corresponding electrode sheet 13 does not exceed the preset temperature threshold, it is determined that the temperature of the electrode sheet 13 is not abnormal.

[0153] In some other embodiments, judging whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0154] Step 233: When it is determined according to the temperature detection signal that any one of the electrode units 33 in the corresponding electrode sheet 13 is abnormal or fails, the electrode sheet 13 is determined to be unqualified.

[0155] Specifically, it is determined whether the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or fails according to the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13; and then it is determined whether the electrode sheet 13 is qualified according to whether the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or fails. When the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or fails, the electrode sheet 13 is determined to be unqualified; when the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is not abnormal or fails, the electrode sheet 13 is determined to be qualified.

[0156] In some other embodiments, judging whether the electrode sheet 13 is abnormal according to the temperature detection signal in step 230 specifically includes the following steps:

[0157] Step 234: when it is determined according to the temperature detection signal that there are abnormal or faulty electrode units 33 in the corresponding electrode sheet 13, the number of the abnormal or faulty electrode units 33 is determined.

[0158] Step 235: When the number of abnormal or faulty electrode units 33 reaches a preset threshold, it is determined that the electrode sheet 13 needs to be replaced.

[0159] Specifically, based on the temperature detection signals of the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13, it is determined whether there is an abnormality or a fault in the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13; then, based on whether there is an abnormality or a fault in the temperature detection units 35 corresponding to the electrode units 33 in the electrode sheet 13, it is determined whether the electrode sheet 13 needs to be replaced.

[0160] For example, when the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13 is abnormal or faulty and the number of the abnormal or faulty temperature detection units 35 exceeds the preset threshold, it is determined that the electrode sheet 13 needs to be replaced; when the number of the temperature detection units 35 that are abnormal or faulty in the electrode sheet 13 does not exceed the preset threshold, it is determined that the electrode sheet 13 does not need to be replaced. The preset threshold is 20% of the total number of all temperature detection units 35 of the electrode sheet 13.

[0161] Reference Fig.10 As shown, the present application also provides a control method of a tumor electric field treatment system, which comprises the following steps:

[0162] Step 210: Control the multiplexing switching unit so that the dual-purpose signal line 19 corresponding to any row group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point, wherein the first switching end 1 of the rectifier switching unit 16 corresponding to the row group in the corresponding electrode sheet 13 is connected to the fixed end 3.

[0163] Step 220 : Control the control switch 54 corresponding to each column group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point to determine the temperature detection signal of each electrode unit 33 in each electrode sheet 13 .

[0164] Step 240: Control the intensity of the alternating electric signal applied to the electrode unit 33 according to the temperature detection signal.

[0165] Specifically, when it is determined that the electrode sheet 13 does not need to be replaced, the alternating electric signal applied to each electrode unit 33 in the electrode sheet 13 is controlled or adjusted according to the temperature detection signal detected by the temperature detection unit 35 corresponding to each electrode unit 33 in the electrode sheet 13. In other words, steps 234-235 can be added between step 240 and step 220.

[0166] In some embodiments, controlling the intensity of the alternating electrical signal applied to the electrode unit 33 according to the temperature detection signal in step 240 specifically includes the following steps:

[0167] Step 241: Compare the temperature of each electrode unit 33 in the electrode sheet 13 with a preset temperature threshold according to the temperature detection signal.

[0168] Step 242: Control the strength of the alternating electric signal according to the comparison result.

[0169] In some embodiments, controlling the strength of the alternating electric signal according to the comparison result in step 242 specifically includes:

[0170] Step 2421: When the temperature at at least one electrode unit 33 exceeds a preset temperature threshold, stop applying the alternating electric signal to the electrode unit 33 of the electrode sheet 13. Specifically, when the temperature detection signals of all the electrode units 33 of the electrode sheet 13 obtained have a temperature exceeding the preset temperature threshold, stop applying the alternating electric signal to the electrode units 33 of the electrode sheet 13. When the temperature detection signals of each electrode unit 33 in the electrode sheet 13 obtained do not exceed the preset temperature threshold, continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13.

[0171] In some embodiments, stopping applying the alternating electric signal to the electrode unit 33 of the electrode sheet 13 in step 2421 specifically includes: stopping applying the alternating electric signal to all electrode units 33 of the electrode sheet 13; or stopping applying the alternating electric signal to all electrode units 33 in the row group of the electrode units 33 in the electrode sheet 13 that exceed a preset temperature threshold.

[0172] Further, when the application of the alternating electric signal to all the electrode units 33 in the row group where the electrode unit 33 exceeding the preset temperature threshold in the electrode sheet 13 is located is stopped, the alternating electric signal continues to be applied to the electrode units 33 in other row groups in the electrode sheet 13. The intensity of the alternating electric signal applied to the electrode units 33 in other row groups in the electrode sheet 13 is adjustable. For example, all the electrode units 33 in the electrode sheet 13 whose corresponding temperature of the temperature detection signal does not exceed the preset temperature threshold and are in a different row from the electrode unit 33 whose temperature detection signal exceeds the preset temperature threshold continue to be applied with the alternating electric signal, and the signal is adjustable.

[0173] In some other embodiments, controlling the strength of the alternating electric signal according to the comparison result in step 242 specifically includes:

[0174] Step 2422: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode units 33 of the electrode sheet 13, wherein the first preset temperature is less than the preset temperature threshold.

[0175] In step 2422, the electric field strengths corresponding to the row groups whose alternating electric signal strengths are increased have the same increase amplitude.

[0176] Step 2423: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if there is at least one electrode unit 33 in the electrode sheet 13 whose temperature exceeds the first preset temperature and is less than the preset temperature threshold, the strength of the alternating electric signal currently applied to the electrode unit 33 of the electrode sheet 13 is maintained unchanged.

[0177] Step 2424: When the temperatures at all electrode units 33 in the electrode sheet 13 do not exceed the preset temperature threshold, if the temperature at at least one electrode unit 33 in the electrode sheet 13 exceeds the second preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit 33 of the electrode sheet 13 is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0178] In step 2424, the electric field strengths corresponding to the row groups whose alternating electric signal strengths are reduced have the same reduction amplitude.

[0179] Exemplarily, when the temperature corresponding to the temperature detection signal is much lower than the preset temperature threshold, the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, or the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged. When the temperature corresponding to the temperature detection signal is close to the preset temperature threshold, the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged, or the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13.

[0180] In some other embodiments, controlling the strength of the alternating electric signal according to the comparison result in step 242 specifically includes:

[0181] Step 2425: When the temperature at at least one electrode unit 33 exceeds a preset temperature threshold, determine the number of over-temperature row groups.

[0182] Step 2426: When the number of over-temperature row groups exceeds a preset number threshold, stop applying the alternating electric signal to all electrode units 33 of the electrode sheet 13 .

[0183] Step 2427: When the number of over-temperature row groups does not exceed the preset number threshold, stop applying the alternating electrical signal to all electrode units 33 in the row group where the electrode units 33 exceeding the preset temperature threshold in the electrode sheet 13 are located.

[0184] Furthermore, when the application of the alternating electric signal to all the electrode units 33 in the row group where the electrode unit 33 exceeding the preset temperature threshold in the electrode sheet 13 is located is stopped, the alternating electric signal continues to be applied to the electrode units 33 in other row groups in the electrode sheet 13. The intensity of the alternating electric signal applied to the electrode units 33 in other row groups in the electrode sheet 13 is adjustable.

[0185] Step 2428: When the number of over-temperature row groups does not exceed the preset number threshold, if the temperature at each electrode unit 33 in the non-over-temperature row group does not exceed the first preset temperature, increase the intensity of the alternating electric signal applied to the electrode unit 33 of the non-over-temperature row group, wherein the first preset temperature is less than the preset temperature threshold.

[0186] In step 2428, the electric field strengths corresponding to the row groups whose alternating electric signal strengths are increased have the same increase amplitude.

[0187] Step 2429: When the number of over-temperature row groups does not exceed the preset number threshold, if the temperature of at least one electrode unit 33 in the non-over-temperature row group exceeds the first preset temperature and is less than the preset temperature threshold, the strength of the alternating electric signal currently applied to the electrode unit 33 of the non-over-temperature row group remains unchanged.

[0188] Step 2430: When the number of over-temperature row groups does not exceed the preset number threshold, if the temperature of at least one electrode unit 33 in the non-over-temperature row group exceeds the second preset temperature and is less than the preset temperature threshold, the intensity of the alternating electric signal applied to the electrode unit 33 of the non-over-temperature row group is reduced, wherein the second preset temperature is greater than the first preset temperature and less than the preset temperature threshold.

[0189] In step 2430, the electric field strengths corresponding to the row groups whose alternating electric signal strengths are reduced have the same reduction amplitude.

[0190] Exemplarily, when the temperature corresponding to the temperature detection signal is much lower than the preset temperature threshold, the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, or the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged. When the temperature corresponding to the temperature detection signal is close to the preset temperature threshold, the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of keeping the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13 unchanged, or the alternating electric signal is continuously applied to each electrode unit 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13.

[0191] Reference Fig.11 As shown, the present application also provides an electrode sheet type identification method, which comprises the following steps:

[0192] Step 210: Control the multiplexing switching unit so that the dual-purpose signal line 19 corresponding to any row group in the corresponding electrode sheet 13 is connected to the corresponding temperature sampling point, wherein the first switching end 1 of the rectifier switching unit 16 corresponding to the row group in the corresponding electrode sheet 13 is connected to the fixed end 3.

[0193] Step 220 : Control the control switch 54 corresponding to each column group so as to sample the analog temperature signal of the corresponding electrode unit 33 based on the corresponding temperature sampling point to determine the temperature detection signal of each electrode unit 33 in each electrode sheet 13 .

[0194] Step 250: Identify the type of the electrode sheet 13 according to the temperature detection signal.

[0195] Specifically, when the electrode sheet 13 is qualified or each temperature detection unit 35 of the electrode sheet 13 has no abnormality or failure, the type of the electrode sheet 13 is identified based on the temperature detection signal detected by the temperature detection unit 35 of each electrode unit 33 in the electrode sheet 13.

[0196] The present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned tumor electric field therapy system 100 or for the above-mentioned electrode sheet 13, and the method includes: combining and controlling a control switch 54 and a bidirectional switching switch 55 electrically connected to the electrode sheet 13 so that each electrode unit 33 of the electrode sheet 13 switches between applying an alternating electric signal and collecting a temperature detection signal.

[0197] Reference Fig.12As shown, the present application also provides a signal control method for tumor electric field therapy, which is used for the above-mentioned electrode sheet 13, and the method includes:

[0198] Step 310: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and executing step 320;

[0199] Step 320: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to collect the temperature detection signals of the electrode units 33 of the electrode sheet 13 in rows or columns and executing step 330;

[0200] Step 330: Determine the combined control mode of the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 according to the collected temperature detection signal and execute step 340;

[0201] Step 340 : Control the working state of each electrode unit 33 of the electrode sheet 13 according to the determined combined control mode of the control switch 54 and the bidirectional switch 55 .

[0202] The working state of each electrode unit 33 of the electrode sheet 13 in step 340 includes at least one of: stopping applying the alternating electric signal and continuing to collect the temperature detection signal and stopping collecting the temperature detection signal and continuing to apply the alternating electric signal. Continuing to apply the alternating electric signal includes continuing to apply the alternating electric signal in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal, or continuing to apply the alternating electric signal in a manner of keeping the voltage or current amplitude of the currently applied alternating electric signal unchanged, or continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal.

[0203] The working state of each electrode unit 33 of the electrode sheet 13 is determined by the temperature detection signal collected by it. Each electrode unit 33 of the electrode sheet 13 is divided into different areas, and each electrode unit 33 in each area can be cyclically switched between applying an alternating electric signal and collecting a temperature detection signal through the combination of a control switch 54 and a bidirectional switch 55.

[0204] The present application embodiment provides another electrode temperature detection method for the tumor electric field treatment system 100, please refer to Fig.13 As shown, the temperature detection method includes:

[0205] Step 510: disconnect the input of the alternating electric signal of the electrode sheet 13, perform combination control on the multiple control switches 54 and the multiple bidirectional switching switches 55, and obtain the temperature detection signal of the temperature sensor 34 of the electrode sheet 13 corresponding to each combination in all the combinations;

[0206] Step 520: sampling and converting the temperature detection signal detected by each temperature sensor 34 in the electrode sheet 13 to obtain a digital temperature signal;

[0207] Step 530: Transmit the digital temperature signal to the electric field generator 30 of the tumor electric field treatment system 100, so that the electric field generator 30 determines the temperature at the corresponding electrode unit 33 according to the digital temperature signal.

[0208] In step 510, the combined control of the plurality of control switches 54 and the plurality of bidirectional switching switches 55 specifically includes:

[0209] Step 511: Control the plurality of bidirectional switches 55 so that the dual-purpose signal lines 19 corresponding to each row group in the corresponding electrode sheet 13 are sequentially connected to the corresponding temperature sampling points; place one bidirectional switch 55 at end 1, and the remaining bidirectional switches 55 at ends 2, so as to conduct the electrical connection between the signal end 35-2 of each temperature detection unit 35 corresponding to each electrode unit 33 in the row group corresponding to the bidirectional switch 55 placed at end 1 and the corresponding ADC unit 52;

[0210] Step 512: Sequentially and individually closing one of the plurality of control switches 54 in a time-sharing manner to collect temperature detection signals detected by each temperature detection unit 35 corresponding to each electrode unit 33 in the corresponding row group one by one.

[0211] In step 512 , by sequentially and individually closing one of the plurality of control switches 54 in a time-sharing manner, the ADC unit 52 and each temperature detection unit 35 in the column group corresponding to the closed control switch 54 can be grounded in sequence.

[0212] Thus, the temperature detection signals of the corresponding temperature detection units 35 in each row group can be obtained in turn, and then after processing by the adapter 20 or the electric field generator 30, the corresponding temperatures of all the electrode units 33 on the electrode sheet 13 can be obtained, thereby making the temperature detection of the patient's body surface more comprehensive and accurate.

[0213] For the tumor electric field therapy system 100 of the embodiment of the present application, the temperature of a single electrode unit 33 can be detected. For example, the temperature of a single electrode unit 33 located in the first column group can be detected. Take the electrode unit 33-1 as an example: disconnect the input of the alternating electric signal, set the bidirectional switch 55 corresponding to the row group where the electrode unit 33-1 that needs to be individually measured is located to end 1, and set the remaining bidirectional switch 55 to end 2; at the same time, turn on and ground the control switch 54 corresponding to the column group where the electrode unit 33-1 that needs to be individually measured is located, and disconnect all the remaining control switches 54. In this way, the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-1 that needs to be individually measured can be sampled to obtain the temperature of the electrode unit 33-1. For example, the first bidirectional switch 55-1 corresponding to the electrode unit 33-1 is placed at the 1 end, and the remaining bidirectional switches (55-2 to 55-4) are all placed at the 2 end; at the same time, the first control switch 54-1 corresponding to the electrode unit 33-1 is closed and grounded, and the remaining control switches (54-2 to 54-5) are all disconnected. In this way, the temperature of the electrode unit 33-1 can be detected. Similarly, the other electrode units 33-6, electrode units 33-11, and electrode units 33-16 in the first column group can also perform separate temperature detection. In addition to the temperature detection of the single electrode unit 33 in the first column group, the temperature detection signals of the other electrode units 33 are combined signals. For example, when the first bidirectional switch 55-1 corresponding to the electrode unit 33-2 is placed at the 1 end, the remaining bidirectional switches (55-2 to 55-4) are all placed at the 2 end; at the same time, the second control switch 54-2 corresponding to the electrode unit 33-2 is closed and grounded, and the remaining control switches (54-1, 54-3 to 54-5) are all disconnected, the temperature detection signal obtained at this time is the combined temperature detection signal of the electrode unit 33-1 and the electrode unit 33-2. The temperature detection signal of the electrode unit 33-2 is obtained by subtracting the temperature detection signal of the electrode unit 33-1 from the combined temperature detection signal.

[0214] The present application also provides another method for applying an alternating electric signal for tumor electric field therapy, which is applied to the above tumor electric field therapy system 100. Please refer to Fig.14 As shown, the alternating electric signal applying method includes:

[0215] Step 610: determining the area (1-4) where the electrode unit 33 to which the alternating electric signal needs to be applied in the electrode sheet 13 is located;

[0216] Step 611: Combining and controlling a plurality of control switches 54 and a plurality of bidirectional switching switches 55 electrically connected to the electrode sheet 13 to apply an alternating electrical signal.

[0217] In step 611, the combination of controlling the multiple control switches 54 and the multiple bidirectional switching switches 55 electrically connected to the electrode sheet 13 is specifically as follows:

[0218] Step 612: disconnect all control switches 54 electrically connected to the electrode sheet 13;

[0219] Step 613: determining the row groups where the electrode units 33 in the areas where the alternating electric signals need to be applied are located according to the areas where the electrode units 33 to which the alternating electric signals need to be applied are located;

[0220] Step 614: determining the bidirectional switches 55 electrically connected to the electrode units 33 in the row groups according to the row groups where the electrode units 33 to which the alternating electric signals need to be applied are located;

[0221] Step 615: Control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be applied so that the electrode unit 33 to which the alternating electric signal needs to be applied is electrically connected to the alternating power line 57 to apply the alternating electric signal; at the same time, control the remaining bidirectional switching switches 55 so that the electrical connection between each electrode unit 33 in the area where the alternating electric signal does not need to be applied and the alternating power line 57 is disconnected to stop applying the alternating electric signal.

[0222] In step 615, "the electrode units to which alternating electric signals need to be applied are electrically connected to the alternating power line 57 to apply the alternating electric signals and the electrode units 33 in the areas where alternating electric signals do not need to be applied are electrically disconnected from the alternating power line 57 to stop applying the alternating electric signals" is achieved by placing the bidirectional switching switches 55 electrically connected to the electrode units 33 in the row groups corresponding to the areas (1-4) in the electrode sheet 13 to which the alternating electric signals are to be applied at their two ends, and placing all the bidirectional switching switches 55 electrically connected to the electrode units 33 in the remaining row groups at their one end.

[0223] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field therapy system 100 of the embodiment of the present application is provided with a preset quantity threshold, a first preset temperature t1, a second preset temperature t2 and a preset temperature threshold t0, wherein the first preset temperature t1 is lower than the second preset temperature t2, and the second preset temperature t2 is lower than the preset temperature threshold t0.

[0224] The present application also provides a method for applying an alternating electric signal based on a temperature detection signal, which is used in the above-mentioned tumor electric field treatment system 100. Fig.15 As shown, the application method includes:

[0225] Step 710: Start the tumor therapeutic field system 100;

[0226] Step 711: Combining and controlling the control switch 54 (also called the grounding switch) electrically connected to the corresponding electrode sheet 13 and the bidirectional switch 55 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13;

[0227] Step 712: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13;

[0228] Step 713: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, and execute step 714 when there is no electrode unit 33 whose temperature exceeds the first preset temperature t1; and execute step 715 when there is an electrode unit 33 whose temperature exceeds the first preset temperature t1;

[0229] Step 714: Continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal and return to step 712;

[0230] Step 715: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2; when there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 716; when there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 717;

[0231] Step 716: Continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in a manner that the voltage or current amplitude of the currently applied alternating electric signal remains unchanged and return to step 712;

[0232] Step 717: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute step 718; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 719;

[0233] Step 718: Continue to apply the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 712;

[0234] Step 719: Determine the number of over-temperature regions and execute step 720, wherein the over-temperature region is a region containing electrode units whose temperature exceeds a preset temperature threshold t0, and the non-over-temperature region is a region in which the temperature of all electrode units does not exceed the preset temperature threshold t0;

[0235] Step 720: Determine whether the number of over-temperature areas exceeds a preset number threshold, and execute step 721 when the number of over-temperature areas exceeds the preset number threshold; and execute step 724 when the number of over-temperature areas does not exceed the preset number threshold.

[0236] Step 721: stop applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and execute step 722;

[0237] Step 722: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13 and executing step 723;

[0238] Step 723: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. When the electrode sheet 13 does not have an electrode unit 33 with a temperature exceeding the first preset temperature t1, return to step 711. When the electrode sheet 13 has an electrode unit 33 with a temperature exceeding the first preset temperature t1, return to step 722.

[0239] Step 724: distinguishing an over-temperature area from a non-over-temperature area according to whether there is an electrode unit 33 whose temperature exceeds a preset temperature threshold t0, and executing step 725 when the area is an over-temperature area, and executing step 726 when the area is a non-over-temperature area;

[0240] Step 725: stop applying the alternating electrical signal to each electrode unit 33 in the over-temperature area and execute step 731;

[0241] Step 726: Determine whether the temperature of each electrode unit 33 in the non-over-temperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 33 in the non-over-temperature area does not exceed the first preset temperature t1, execute step 727. When the temperature of each electrode unit 33 in the non-over-temperature area exceeds the first preset temperature t1, execute step 728.

[0242] Step 727: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal and execute step 731;

[0243] Step 728: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2. When the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 729. When the temperature of each electrode unit 33 in the non-overtemperature area exceeds the second preset temperature t2, execute step 730.

[0244] Step 729: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner that the voltage or current amplitude of the currently applied alternating electric signal remains unchanged and execute step 731;

[0245] Step 730: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and execute step 731;

[0246] Step 731: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to reacquire the temperature of each electrode unit 33 of the electrode sheet 13 and select to execute step 732 or step 734, wherein the temperature of each electrode unit 33 of the electrode sheet 13 includes the temperature of each electrode unit 33 in the over-temperature area and the temperature of each electrode unit 33 in the non-over-temperature area;

[0247] Step 732: Determine whether the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1, execute step 733. When the temperature of each electrode unit 33 in the over-temperature area exceeds the first preset temperature t1, return to step 731.

[0248] Step 733: re-determine the area as a non-overtemperature area and execute step 734;

[0249] Step 734: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the first preset temperature t1. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the first preset temperature t1, execute step 735. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the first preset temperature t1, execute step 736.

[0250] Step 735: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied alternating electric signal and return to step 712;

[0251] Step 736: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the second preset temperature t2. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the second preset temperature t2, execute step 737. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the second preset temperature t2, execute step 738.

[0252] Step 737: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area in a manner that the voltage or current amplitude of the currently applied alternating electric signal remains unchanged and return to step 712;

[0253] Step 738: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the preset temperature threshold t0. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the preset temperature threshold t0, execute step 739. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the preset temperature threshold t0, return to step 719.

[0254] Step 739 : Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 712 .

[0255] The process of combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 in step 711 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet is specifically as follows:

[0256] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that applies an alternating electrical signal to each electrode unit 33; or

[0257] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that electrically connects each electrode unit 33 to the alternating power line 57; or

[0258] All control switches 54 electrically connected to the corresponding electrode sheets 13 are disconnected, and at the same time, all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 are switched to their respective two ends.

[0259] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in step 712, step 722, and step 731 is specifically as follows:

[0260] Control the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, control each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch from the end at which the alternating electric signal is applied to each electrode unit 33 to the end at which the temperature of each electrode unit 33 is collected in sequence in a time-sharing manner, and the remaining two-way switching switches 55 are all switched from the end at which the temperature of each electrode unit 33 is collected to the end at which the alternating electric signal is applied to each electrode unit 33, and at the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0261] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch from its two ends, which apply the alternating electric signal to each electrode unit 33, to its one end in a time-sharing manner, and controlling the remaining two-way switching switches 55 to switch from its one end to its two ends, which apply the alternating electric signal to each electrode unit 33, and at the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0262] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52 in a time-division order, and the remaining two-way switching switches 55 to be switched from being electrically connected to the corresponding ADC unit 52 to being electrically connected to the alternating power line 57, and at the same time each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in a time-division order to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0263] The power supply switch 40 of the electric field generator 30 is controlled to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, and each of the two-way switching switches 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating electric signal to transmitting a direct current signal or a temperature detection signal in a time-sharing manner, and the remaining two-way switching switches 55 switch from transmitting a direct current signal or a temperature detection signal to transmitting an alternating electric signal. At the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode units 33 of the electrode sheet 13 is closed in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0264] The first preset temperature in step 713, step 723, step 726, step 732, and step 734 is 40°C-40.3°C, preferably 40.2°C. The second preset temperature in step 715, step 728, and step 736 is 40.4°C to 40.6°C, preferably 40.5°C; the preset temperature threshold in step 717 and step 738 is 41°C to 41.5°C, preferably 41°C; the preset quantity threshold in step 720 is preferably 2.

[0265] The process of continuing to apply the alternating electric signal in step 714, step 716, step 718, step 727, step 729, step 730, step 735, step 737, and step 739 is specifically as follows:

[0266] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied to conduct the alternating electric signal transmission path electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0267] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied to switch from its respective 1 end to its respective 2 end so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0268] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the two-way switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, so that both ends of each of the two-way switch 55 are electrically connected to the alternating power line 57 so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0269] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied so that the two ends of each of the two switches are closed and one end is disconnected, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0270] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied so that the electrode unit 33 to which the alternating electric signal needs to continue to be applied switches from transmitting the temperature detection signal to applying the alternating electric signal.

[0271] Increasing the voltage or current amplitude of the currently applied alternating electric signal in step 714, step 727, and step 735 is specifically to boost the voltage of the currently applied alternating electric signal in a manner of a DC voltage amplitude increment of 0.03 V per second.

[0272] Continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal as described in step 718, step 730, and step 739 specifically means continuing to apply the alternating electric signal in a manner of 5V less than the voltage amplitude of the currently applied alternating electric signal and continuing for 3 minutes.

[0273] The process of stopping applying the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in step 721 is specifically as follows:

[0274] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to disconnect the electrical connection between each electrode unit 33 of the electrode sheet 13 and the alternating power line 57; or

[0275] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all ends from the end where the electrode units 33 are applied with an alternating electrical signal to the end where the electrode units 33 are subjected to temperature collection; or

[0276] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all two ends of the bidirectional switch 55 from applying the alternating electric signal to one end of the bidirectional switch 55; or

[0277] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from electrically connecting each electrode unit 33 with the alternating power line 57 to electrically connecting each electrode unit 33 with the corresponding ADC unit 52; or

[0278] The bidirectional switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0279] The process of stopping applying the alternating electrical signal to each electrode unit 33 in the over-temperature area in step 725 is specifically as follows:

[0280] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to disconnect the electrical connection between each electrode unit 33 in the over-temperature area and the alternating power line 57; or

[0281] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature zone to switch all ends from the end where the electrode units 33 in the over-temperature zone apply an alternating electrical signal to the end where the electrode units 33 in the over-temperature zone collect temperature; or

[0282] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch all two ends of the bidirectional switch 55 that applies an alternating electrical signal to each electrode unit 33 in the over-temperature region to one end; or

[0283] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch each electrode unit 33 in the over-temperature region from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52; or

[0284] The bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area is controlled to switch each electrode unit 33 in the over-temperature area from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0285] In the above control method, the tumor electric field therapy system 100 includes at least two pairs of electrodes 13 to alternately apply alternating electric fields with different directions, and each electrode 13 can alternately switch between applying alternating electric signals and transmitting temperature detection signals.

[0286] The first controller 51 or the electric field generator 30 in the adapter 20 of the tumor electric field treatment system 100 of the embodiment of the present application is also provided with a third preset temperature t3, which is higher than the second preset temperature t2 but still lower than the preset temperature threshold t0. The third preset temperature t3 is closer to the preset temperature threshold t0 than the second preset temperature t2. The embodiment of the present application also provides an alternating electric signal control method based on a temperature detection signal, which is used in the above tumor electric field treatment system, Fig.16 As shown, the alternating electric signal control method includes:

[0287] Step 810: Start the tumor therapeutic field system 100;

[0288] Step 811: Combining and controlling the control switch 54 (also called the grounding switch) electrically connected to the corresponding electrode sheet 13 and the bidirectional switch 55 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet 13;

[0289] Step 812: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13;

[0290] Step 813: Determine whether there is an electrode unit 33 whose temperature exceeds the first preset temperature t1, and execute step 814 when there is no electrode unit 33 whose temperature exceeds the first preset temperature t1; and execute step 815 when there is an electrode unit 33 whose temperature exceeds the first preset temperature t1;

[0291] Step 814: Continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0292] Step 815: Determine whether there is an electrode unit 33 whose temperature exceeds the second preset temperature t2; when there is no electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 816; when there is an electrode unit 33 whose temperature exceeds the second preset temperature t2, execute step 817;

[0293] Step 816: Continue to apply the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in a manner that the voltage or current amplitude of the currently applied alternating electric signal remains unchanged and return to step 812;

[0294] Step 817: Determine whether there is an electrode unit 33 whose temperature exceeds the third preset temperature t3. If there is no electrode unit 33 whose temperature exceeds the third preset temperature t3, execute step 818; if there is an electrode unit whose temperature exceeds the third preset temperature t3, execute step 819;

[0295] Step 818: Continue to apply the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0296] Step 819: Determine whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0. If there is no electrode unit 33 whose temperature exceeds the preset temperature threshold t0, execute step 820; if there is an electrode unit whose temperature exceeds the preset temperature threshold t0, execute step 821;

[0297] Step 820: Continue to apply the alternating electric signal to all electrode units 33 of the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0298] Step 821: Determine the number of over-temperature regions and execute step 822, wherein the over-temperature region is a region containing electrode units whose temperature exceeds a preset temperature threshold t0, and the non-over-temperature region is a region in which the temperature of all electrode units does not exceed the preset temperature threshold t0;

[0299] Step 822: Determine whether the number of over-temperature areas exceeds a preset number threshold, and execute step 823 when the number of over-temperature areas exceeds the preset number threshold; and execute step 826 when the number of over-temperature areas does not exceed the preset number threshold;

[0300] Step 823: stop applying the alternating electrical signal to each electrode unit 33 of the electrode sheet 13 and execute step 824;

[0301] Step 824: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to obtain the temperature of each electrode unit 33 of the electrode sheet 13 and executing step 825;

[0302] Step 825: Determine whether there is an electrode unit 33 with a temperature exceeding the first preset temperature t1. When the electrode sheet 13 does not have an electrode unit 33 with a temperature exceeding the first preset temperature t1, return to step 811. When the electrode sheet 13 has an electrode unit 33 with a temperature exceeding the first preset temperature t1, return to step 824.

[0303] Step 826: Distinguish the over-temperature area and the non-over-temperature area according to whether there is an electrode unit 33 whose temperature exceeds the preset temperature threshold t0, and execute step 827 when the area is the over-temperature area, and execute step 828 when the area is the non-over-temperature area;

[0304] Step 827: stop applying the alternating electrical signal to each electrode unit 33 in the over-temperature area and execute step 835;

[0305] Step 828: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the first preset temperature t1, execute step 829. When the temperature of each electrode unit 33 in the non-overtemperature area exceeds the first preset temperature t1, execute step 830.

[0306] Step 829: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner of increasing the voltage or current amplitude of the currently applied alternating electric signal and execute step 835;

[0307] Step 830: Determine whether the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2. When the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the second preset temperature t2, execute step 831. When the temperature of each electrode unit 33 in the non-overtemperature area exceeds the second preset temperature t2, execute step 832.

[0308] Step 831: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner that the voltage or current amplitude of the currently applied alternating electric signal remains unchanged and execute step 835;

[0309] Step 832: Determine whether there is an electrode unit 33 in the non-overtemperature area whose temperature exceeds the third preset temperature t3. When the temperature of each electrode unit 33 in the non-overtemperature area does not exceed the third preset temperature t3, execute step 833. When the temperature of each electrode unit 33 in the non-overtemperature area exceeds the third preset temperature t3, execute step 834.

[0310] Step 833: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and execute step 835;

[0311] Step 834: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area of ​​the electrode sheet 13 in a manner of further reducing the voltage or current amplitude of the currently applied alternating electric signal and execute step 835;

[0312] Step 835: Combining and controlling the control switch 54 and the bidirectional switch 55 electrically connected to the electrode sheet 13 to reacquire the temperature of each electrode unit 33 of the electrode sheet 13 and selecting to execute step 836 or step 838, wherein the temperature of each electrode unit 33 of the electrode sheet 13 includes the temperature of each electrode unit 33 in the over-temperature area and the temperature of each electrode unit 33 in the non-over-temperature area;

[0313] Step 836: Determine whether the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1. When the temperature of each electrode unit 33 in the over-temperature area does not exceed the first preset temperature t1, execute step 837. When the temperature of each electrode unit 33 in the over-temperature area exceeds the first preset temperature t1, return to step 835.

[0314] Step 837: re-determine the area as a non-overtemperature area and execute step 838;

[0315] Step 838: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the first preset temperature t1. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the first preset temperature t1, execute step 839. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the first preset temperature t1, execute step 840.

[0316] Step 839: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area by increasing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0317] Step 840: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the second preset temperature t2. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the second preset temperature t2, execute step 841. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the second preset temperature t2, execute step 842.

[0318] Step 841: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area in a manner that the voltage or current amplitude of the currently applied alternating electric signal remains unchanged and return to step 812;

[0319] Step 842: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the third preset temperature t3. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the third preset temperature t3, execute step 843. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the third preset temperature t3, execute step 844.

[0320] Step 843: Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812;

[0321] Step 844: Determine whether the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the preset temperature threshold t0. When the temperatures of the electrode units 33 in the non-over-temperature area do not exceed the preset temperature threshold t0, execute step 845. When the temperatures of the electrode units 33 in the non-over-temperature area exceed the preset temperature threshold t0, return to step 821.

[0322] Step 845 : Continue to apply the alternating electric signal to each electrode unit 33 in the non-overtemperature area in a manner of further reducing the voltage or current amplitude of the currently applied alternating electric signal and return to step 812 .

[0323] The process of combining the control switch 54 and the bidirectional switch 55 electrically connected to the corresponding electrode sheet 13 in step 811 to apply an alternating electrical signal to each electrode unit 33 of the electrode sheet is specifically as follows:

[0324] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that applies an alternating electrical signal to each electrode unit 33; or

[0325] Disconnect all control switches 54 electrically connected to the corresponding electrode sheet 13, and simultaneously switch all bidirectional switches 55 electrically connected to the corresponding electrode sheet 13 to one end that electrically connects each electrode unit 33 to the alternating power line 57; or

[0326] All control switches 54 electrically connected to the corresponding electrode sheets 13 are disconnected, and at the same time, all bidirectional switches 55 electrically connected to the corresponding electrode sheets 13 are switched to their respective two ends.

[0327] The process of obtaining the temperature of each electrode unit 33 of the electrode sheet 13 in step 812, step 824, and step 835 is specifically as follows:

[0328] Control the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, control each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch from the end at which the alternating electric signal is applied to each electrode unit 33 to the end at which the temperature of each electrode unit 33 is collected in sequence in a time-sharing manner, and the remaining two-way switching switches 55 are all switched from the end at which the temperature of each electrode unit 33 is collected to the end at which the alternating electric signal is applied to each electrode unit 33, and at the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in sequence in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0329] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch from its two ends, which apply the alternating electric signal to each electrode unit 33, to its one end in a time-sharing manner, and controlling the remaining two-way switching switches 55 to switch from its one end to its two ends, which apply the alternating electric signal to each electrode unit 33, and at the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0330] Controlling the power switch 40 of the electric field generator 30 to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, controlling each of the two-way switching switches 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52 in a time-division order, and the remaining two-way switching switches 55 to be switched from being electrically connected to the corresponding ADC unit 52 to being electrically connected to the alternating power line 57, and at the same time each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode unit 33 of the electrode sheet 13 is closed in a time-division order to obtain the temperature of each electrode unit 33 of the electrode sheet 13; or

[0331] The power supply switch 40 of the electric field generator 30 is controlled to disconnect the alternating electric signal applied to each electrode unit 33 of the electrode sheet 13, and each of the two-way switching switches 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating electric signal to transmitting a direct current signal or a temperature detection signal in a time-sharing manner, and the remaining two-way switching switches 55 switch from transmitting a direct current signal or a temperature detection signal to transmitting an alternating electric signal. At the same time, each rectifying switching unit 16 is linked with the action of the corresponding two-way switching switch 55, so that the temperature detection unit 35 corresponding to the corresponding electrode unit 33 is connected to the corresponding dual-purpose signal line 19, and the control switch 54 electrically connected to the electrode units 33 of the electrode sheet 13 is closed in a time-sharing manner to obtain the temperature of each electrode unit 33 of the electrode sheet 13.

[0332] The first preset temperature in step 813, step 825, step 828, step 836, and step 838 is 40°C-40.3°C, preferably 40.2°C. The second preset temperature in step 815, step 830, and step 840 is 40.4°C to 40.6°C, preferably 40.5°C; the third preset temperature in step 817, step 832, and step 842 is 40.7°C to 40.9°C, preferably 40.8°C; the preset temperature threshold in step 819 and step 844 is 41°C to 41.5°C, preferably 41°C; the preset quantity threshold in step 822 is preferably 2.

[0333] The process of continuing to apply the alternating electric signal described in step 814, step 816, step 818, step 820, step 829, step 831, step 833, step 834, step 839, step 841, step 843, and step 845 is specifically as follows:

[0334] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied to conduct the alternating electric signal transmission path electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0335] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied to switch from its respective 1 end to its respective 2 end so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0336] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the two-way switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, so that both ends of each of the two-way switch 55 are electrically connected to the alternating power line 57 so as to continue to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0337] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied, and at the same time control the bidirectional switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to be continuously applied so that the two ends of each of the two switches are closed and one end is disconnected, thereby continuing to apply the alternating electric signal to the electrode unit 33 to which the alternating electric signal needs to be continuously applied; or

[0338] Disconnect the control switch 54 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied, and at the same time control the bidirectional switching switch 55 electrically connected to the electrode unit 33 to which the alternating electric signal needs to continue to be applied so that the electrode unit 33 to which the alternating electric signal needs to continue to be applied switches from transmitting the temperature detection signal to applying the alternating electric signal.

[0339] The method of increasing the voltage or current amplitude of the currently applied alternating electric signal in step 814, step 829, and step 839 is to continue to apply the alternating electric signal by boosting the currently applied alternating electric signal with a DC voltage amplitude increment of 0.03V per second and then continue to apply the alternating electric signal.

[0340] Continuing to apply the alternating electric signal in a manner of reducing the voltage or current amplitude of the currently applied alternating electric signal as described in step 818, step 820, step 833, step 834, step 843 and step 845 specifically means continuing to apply the alternating electric signal in a manner of 5V less than the voltage amplitude of the currently applied alternating electric signal and continuing for 3 minutes.

[0341] The process of stopping applying the alternating electric signal to each electrode unit 33 of the electrode sheet 13 in step 823 is specifically as follows:

[0342] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to disconnect the electrical connection between each electrode unit 33 of the electrode sheet 13 and the alternating power line 57; or

[0343] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all ends from the end where the electrode units 33 are applied with an alternating electrical signal to the end where the electrode units 33 are subjected to temperature collection; or

[0344] Control the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch all two ends of the bidirectional switch 55 from applying the alternating electric signal to one end of the bidirectional switch 55; or

[0345] Controlling the bidirectional switch 55 electrically connected to the electrode sheet 13 to switch the electrode sheet 13 from electrically connecting each electrode unit 33 with the alternating power line 57 to electrically connecting each electrode unit 33 with the corresponding ADC unit 52; or

[0346] The bidirectional switch 55 electrically connected to the electrode sheet 13 is controlled to switch each electrode unit 33 of the electrode sheet 13 from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0347] The process of stopping applying the alternating electrical signal to each electrode unit 33 in the over-temperature area in step 827 is specifically as follows:

[0348] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area to disconnect the electrical connection between each electrode unit 33 in the over-temperature area and the alternating power line 57; or

[0349] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature zone to switch all ends from the end where the electrode units 33 in the over-temperature zone apply an alternating electrical signal to the end where the electrode units 33 in the over-temperature zone collect temperature; or

[0350] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch all two ends of the bidirectional switch 55 that applies an alternating electrical signal to each electrode unit 33 in the over-temperature region to one end; or

[0351] Control the bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature region to switch each electrode unit 33 in the over-temperature region from being electrically connected to the alternating power line 57 to being electrically connected to the corresponding ADC unit 52; or

[0352] The bidirectional switch 55 electrically connected to each electrode unit 33 in the over-temperature area is controlled to switch each electrode unit 33 in the over-temperature area from transmitting an alternating current signal to transmitting a direct current signal or a temperature detection signal.

[0353] When the tumor electric field therapy system 100 is in a standby state before starting work, no alternating electric signal is applied to the electrode unit 33, and the first controller 51 of the adapter 20 or the second controller 37 of the electric field generator 30 controls the bidirectional switching switch 55 (one of 55-1 to 55-4) to switch to end 1 in turn, and the control switches 54 (54-1 to 54-5) are turned on in turn, and the ADC unit 52 obtains the temperature detection signal of the temperature detection unit 35 corresponding to each electrode unit 33 (33-1 to 33-20) in turn.

[0354] When the first control switch 54-1 is turned on, the control switches (54-2, 54-3, 54-4, 54-5) are all turned off, and the bidirectional switching switches (55-1 to 55-4) are sequentially placed at the 1 end, the ADC unit 52 receives the temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit (33-1, 33-6, 33-11, 33-16);

[0355] When the second control switch 54-2 is turned on, the control switches (54-1, 54-3, 54-4, 54-5) are all turned off, and the bidirectional switching switches (55-1 to 55-4) are sequentially placed at end 1, the first detection channel A of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-1 and the electrode unit 33-2, the second detection channel B of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-6 and the electrode unit 33-7, the third detection channel C of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-11 and the electrode unit 33-12, and the fourth detection channel D of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-16 and the electrode unit 33-17;

[0356] When the third control switch 54-3 is turned on, the control switches (54-1, 54-2, 54-4, 54-5) are all turned off, and the bidirectional switching switches (55-1 to 55-4) are sequentially placed at end 1, the first detection channel A of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-1, the electrode unit 33-2 and the electrode unit 33-3, the second detection channel B of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-6, the electrode unit 33-7 and the electrode unit 33-8, the third detection channel C of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-11, the electrode unit 33-12 and the electrode unit 33-13, and the fourth detection channel D of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-16, the electrode unit 33-17 and the electrode unit 33-18;

[0357] When the fourth control switch 54-4 is turned on, the control switches (54-1, 54-2, 54-3, 54-5) are all turned off, and the bidirectional switches (55-1 to 55-4) are sequentially placed at the 1 end, the first detection channel A of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-1, the electrode unit 33-2, the electrode unit 33-3, and the electrode unit 33-4, and the second detection channel B of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-6, the electrode unit 33-7, and the electrode unit 33- 8. The combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-9, the third detection channel C of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-11, the electrode unit 33-12, the electrode unit 33-13, and the electrode unit 33-14, and the fourth detection channel D of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-16, the electrode unit 33-17, the electrode unit 33-18, and the electrode unit 33-19;

[0358] When the fifth control switch 54-5 is turned on, the control switches (54-1, 54-2, 54-3, 54-4) are all turned off, and the bidirectional switches (55-1 to 55-4) are sequentially placed at the 1 end, the first detection channel A of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-1, the electrode unit 33-2, the electrode unit 33-3, the electrode unit 33-4, and the electrode unit 33-5, and the second detection channel B of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-6, the electrode unit 33-7, the electrode unit 33-8, and the electrode unit 33-9. The third detection channel C of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-11, the electrode unit 33-12, the electrode unit 33-13, the electrode unit 33-14, and the electrode unit 33-15, and the fourth detection channel D of the ADC unit 52 receives the combined temperature detection signal of the temperature detection unit 35 corresponding to the electrode unit 33-16, the electrode unit 33-17, the electrode unit 33-18, the electrode unit 33-19, and the electrode unit 33-20. Thus, through the processing method described above, the temperature detection signal corresponding to each electrode unit 33 can be obtained.

[0359] The first controller 51 receives the temperature detection signal of the temperature detection unit 35 corresponding to each electrode unit 33 (33-1 to 33-20) through the ADC unit 52, and transmits it to the AC signal generator 39 of the electric field generator 30 through the first communication unit 56 and the second communication unit 38, and then controls or adjusts the alternating electric signal applied to each electrode unit 33 through the second controller 37.

[0360] In the embodiments of the present application, it should be noted that when the bidirectional switching switch is controlled to be turned on to end 1, the first switching end of the corresponding rectifier switching unit is connected to the fixed end, and when the bidirectional switching switch is controlled to be turned on to end 2, the second switching end of the corresponding rectifier switching unit is connected to the fixed end.

[0361] Although various operations are depicted in the drawings as being in a particular order, this should not be understood as requiring that the operations must be performed in the particular order shown or in sequential order, nor should it be understood as requiring that all illustrated operations must be performed to achieve desirable results.

[0362] Embodiment 2:

[0363] In the tumor electric field treatment system 100 shown in Example 1, two adjacent electrode units 33 in the electrode sheet 13 are connected by a connecting strip (not numbered), and the connection method of the 10 electrode units 33 on the left side of the electrode sheet 13 is asymmetric to the connection method of the 10 electrode units 33 on the right side. The 10 electrode units 33 on the left side of the electrode sheet 13 have 4 electrode units 33 at the free ends, and the 10 electrode units 33 on the right side of the electrode sheet 13 have 5 electrode units 33 at the free ends. Different from the tumor electric field treatment system 100 shown in Example 1, the reference Fig.17 , another tumor electric field therapy system 100A is described below, whose main concept is the same as the above-mentioned tumor electric field therapy system 100, and the spatial arrangement of its electrode units 33A is the same as the spatial arrangement of the electrode units 33 of the tumor electric field therapy system 100 shown in Example 1, the difference is: the connection method of the electrode units 33A in the electrode sheet 13A of the tumor electric field therapy system 100A is different, the connection method of the 10 electrode units 33A on the left side of the electrode sheet 13A and the connection method of the 10 electrode units 33A on the right side are symmetrical, the 10 electrode units 33A on the left side of the electrode sheet 13A have 4 electrode units 33A at the free ends, and the 10 electrode units 33A on the right side of the electrode sheet 13A have 4 electrode units 33A at the free ends. Specifically, along the column upward, only the two adjacent electrode units 33 in the third and fourth columns are connected by a connecting strip (unnumbered), and the two adjacent electrode units 33 in the other four columns are not connected by a connecting strip. The bridging portion (unnumbered) connects the two connecting strips (unnumbered) that are opposite to each other in the column upward.

[0364] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 1 and will not be repeated here.

[0365] Embodiment 3:

[0366] In the tumor electric field treatment system 100 shown in Example 1, each electrode sheet 13 includes 20 electrode units 33. Fig.18 and Fig.19 , another tumor electric field treatment system 100B is described below, and its main concept is the same as the above-mentioned tumor electric field treatment system 100, except that: each electrode sheet 13B of the tumor electric field treatment system 100B includes 13 electrode units 33B, each electrode sheet 13B does not have an electrode unit 33B at a free end, and the number of electrode units 33B contained in each row group and each column group of each electrode sheet 13B is different. Specifically, these 13 electrode units 33B are arranged in five row groups and five column groups in a spatial structure. Each of the first row and the fifth row includes two electrode units 33B, and the two electrode units 33B in each row are respectively located on the second column and the fourth column; each of the second to fourth rows includes three electrode units 33B, and the three electrode units 33B in each row are respectively located on the first column, the third column and the fifth column. The two adjacent electrode units 33B in each row of the above-mentioned five rows of electrode units 33B are connected by a connecting belt (unnumbered). The two adjacent electrode units 33B in each of the first column, the third column and the fifth column are connected by a connecting belt (unnumbered). The electrode unit 33B in the second column of the first row is connected to the electrode unit 33B in the first column of the second row and the third column of the first row respectively by a connecting belt (unnumbered); the electrode unit 33B in the fourth column of the first row is connected to the electrode unit 33B in the third column of the second row and the fifth column of the first row respectively by a connecting belt (unnumbered); the electrode unit 33B in the second column of the fifth row is connected to the electrode unit 33B in the first column of the fourth row and the third column of the fourth row respectively by a connecting belt (unnumbered); the electrode unit 33B in the fourth column of the fifth row is connected to the electrode unit 33B in the third column of the fourth row and the fifth column of the fourth row respectively by a connecting belt (unnumbered).

[0367] Fig.19 for Fig.18The circuit connection diagram of the electrode sheet 13B and the adapter 20B of the tumor electric field treatment system 100B is shown. The multiple electrode units 33B are configured into multiple row groups and multiple column groups in the circuit connection. In this embodiment, each electrode sheet 13B is provided with 13 electrode units 33B, and the 13 electrode units 33B are arranged in the order of 1 to 13 in the circuit connection. The electrode units 33-1B to 33-13B are divided into three row groups and five column groups, that is, the 13 electrode units 33B are arranged in three rows and five columns in the circuit connection. The first row group and the second row group each include 5 electrode units 33B, the third row group includes 3 electrode units 33B, the first column group to the third column group each include 3 electrode units 33B, and the fourth column group to the fifth column group each include 2 electrode units 33B.

[0368] The electrode sheet 13B includes five grounding wires 18B, namely, a first grounding wire 18-1B, a second grounding wire 18-2B, a third grounding wire 18-3B, a fourth grounding wire 18-4B and a fifth grounding wire 18-5B, and the five grounding wires 18B are respectively arranged in one-to-one correspondence with five column groups. Among the five column groups of the electrode sheet 13B, the first column group includes electrode unit 33-1B, electrode unit 33-6B, and electrode unit 33-11B, the second column group includes electrode unit 33-2B, electrode unit 33-7B, and electrode unit 33-12B, the third column group includes electrode unit 33-3B, electrode unit 33-8B, and electrode unit 33-13B, the fourth column group includes electrode unit 33-4B and electrode unit 33-9B, and the fifth column group includes electrode unit 33-5B and electrode unit 33-10B. Specifically, the first grounding wire 18-1B is used to ground the grounding ends of the respective corresponding temperature detection units 35B in the electrode unit 33-1B, the electrode unit 33-6B, and the electrode unit 33-11B in the first column group; the second grounding wire 18-2B is used to ground the grounding ends of the respective corresponding temperature detection units 35B in the electrode unit 33-2B, the electrode unit 33-7B, and the electrode unit 33-12B in the second column group; the third grounding wire 18-3B is used to ground the grounding ends of the respective corresponding temperature detection units 35B in the electrode unit 33-3B, the electrode unit 33-8B, and the electrode unit 33-13B in the third column group; the fourth grounding wire 18-4B is used to ground the grounding ends of the respective corresponding temperature detection units 35B in the electrode unit 33-4B and the electrode unit 33-9B in the fourth column group; the fifth grounding wire 18-5B is used to ground the grounding ends of the respective corresponding temperature detection units 35B in the electrode unit 33-5B and the electrode unit 33-10B in the fifth column group.

[0369] Different from the above-mentioned Embodiment 1 or Embodiment 2, the multi-channel dual-purpose signal line 19B of this embodiment includes only three dual-purpose signal lines, namely the first dual-purpose signal line 19-1B, the second dual-purpose signal line 19-2B and the third dual-purpose signal line 19-3B. The first dual-purpose signal line 19-1B, the second dual-purpose signal line 19-2B and the third dual-purpose signal line 19-3B are respectively arranged in one-to-one correspondence with the three row groups of the electrode unit 33B of the electrode sheet 13B. Specifically, the five electrode units 33B from electrode unit 33-1B to electrode unit 33-5B are connected in parallel to the second switching end 2 of the corresponding rectifying switching unit 16B, and the temperature detection unit 35B of each electrode unit 33B is connected in series to the first switching end 1 of the corresponding rectifying switching unit 16B, and the fixed end 3 of the rectifying switching unit 16B is connected to the first dual-purpose signal line 19-1B; the five electrode units 33B from electrode unit 33-6B to electrode unit 33-10B are connected in parallel to the second switching end 2 of the corresponding rectifying switching unit 16B, and the temperature detection unit 35B of each electrode unit 33B is connected in series to the first switching end 1 of the corresponding rectifying switching unit 16B. The temperature detection unit 35B is connected in series to the first switching end 1 of the corresponding rectifying switching unit 16B, and the fixed end 3 of the rectifying switching unit 16B is connected to the second dual-purpose signal line 19-2B; the three electrode units 33B from the electrode unit 33-11B to the electrode unit 33-13B are connected in parallel to the second switching end 2 of the corresponding rectifying switching unit 16B, and the temperature detection unit 35B of each electrode unit 33B is connected in series to the first switching end 1 of the corresponding rectifying switching unit 16B, and the fixed end 3 of the rectifying switching unit 16B is connected to the third dual-purpose signal line 19-3B. Of course, in some examples, the multi-channel dual-purpose signal line 19B may also include four dual-purpose signal lines, wherein the fourth dual-purpose signal line is not electrically connected to the signal end of any temperature detection unit 35B.

[0370] Specifically, in this embodiment, the plurality of control switches 54B in the corresponding group of control switches 54B are respectively a first control switch 54-1B, a second control switch 54-2B, a third control switch 54-3B, a fourth control switch 54-4B and a fifth control switch 54-5B. The first control switch 54-1B, the second control switch 54-2B, the third control switch 54-3B, the fourth control switch 54-4B and the fifth control switch 54-5B respectively control the closing or opening of the corresponding grounding line 18B of the same electrode sheet 13B. The first control switch 54-1B is used to control the closing or disconnection of the first grounding line 18-1B of the corresponding electrode sheet 13B, and can cooperate with the corresponding group of two-way switching switches 55B and the corresponding rectifying switching unit 16B to control the temperature detection units 35B corresponding to the three electrode units 33B in the first column group of the electrode sheet 13B, namely, the electrode unit 33-1B, the electrode unit 33-6B, and the electrode unit 33-11B, to be powered on or off respectively; the second control switch 54-2B is used to control the closing or disconnection of the second grounding line 18-2B of the electrode sheet 13B, and can cooperate with the corresponding group of two-way switching switches 55B and the corresponding rectifying switching unit 16B to control the multiple electrode units 33B in the first column group and the second column group of the electrode sheet 13B (the multiple electrode units can be: electrode unit 33-1B and electrode unit 33-6B, respectively). The temperature detection units 35B corresponding to the electrode units 33-3B, electrode units 33-6B and electrode units 33-7B, electrode units 33-11B and electrode units 33-12B) are powered on and off respectively; the third control switch 54-3B is used to control the closing or opening of the third grounding line 18-3B of the electrode sheet 13B, and then can cooperate with the corresponding group of bidirectional switching switches 55B and the corresponding rectifying switching unit 16B to control the power on and off of each temperature detection unit 35B corresponding to multiple electrode units 33B (electrode units 33-1B to 33-3B, electrode units 33-6B to 33-8B, electrode units 33-11B to 33-13B) in the first column group, the second column group and the third column group of the electrode sheet 13B; the fourth control switch 54-4B and the fifth control switch 54-5B are the same, and they are not repeated here.

[0371] Taking the electrical connection between an electrode sheet 13B and an adapter 20B as an example, the multiple bidirectional switches 55B in the corresponding group of bidirectional switches 55B are respectively a first bidirectional switch 55-1B, a second bidirectional switch 55-2B, a third bidirectional switch 55-3B and a fourth bidirectional switch 55-4B. The first bidirectional switch 55-1B, the second bidirectional switch 55-2B, and the third bidirectional switch 55-3B respectively control the switching between the transmission of the alternating electric signal and the transmission of the temperature detection signal in the corresponding one of the multiplexed dual-purpose signal lines 19B of the same electrode sheet 13B. Specifically, the first bidirectional switch 55-1B is used to control the switching of the first dual-purpose signal line 19-1B of the corresponding electrode sheet 13B between transmitting alternating electric signals and transmitting temperature detection signals, thereby controlling the switching between the conduction of each electrode unit 33B from the electrode unit 33-1B to the electrode unit 33-5B in the first row group of the electrode sheet 13B and the conduction of the signal ends of each temperature detection unit 35B corresponding to the electrode unit 33-1B to the electrode unit 33-5B in the first row group, and cooperating with the corresponding first control switch 54-1B, the second control switch 54-2B, the third control switch 54-3B, the fourth control switch 54-4B, and the fifth control switch 54-5B, so that the first row of electrode units 33-1B to the electrode unit 33-5B transmit alternating electric signals to the patient or the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 35B corresponding to the electrode units 33B are sampled and output to the corresponding ADC unit 52B respectively. The second bidirectional switch 55-2B is used to control the switching of the second dual-purpose signal line 19-2B of the corresponding electrode sheet 13B between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the conduction of each electrode unit 33B from the electrode unit 33-6B to the electrode unit 33-10B in the second row group of the electrode sheet 13B and the conduction of the signal ends of each temperature detection unit 35B corresponding to the electrode unit 33-6B to the electrode unit 33-10B in the second row group, and cooperates with the corresponding first control switch 54-1B, the second control switch 54-2B, the third control switch 54-3B, the fourth control switch 54-4B, and the fifth control switch 54-5B, so that the second row electrode unit 33-6B to the electrode unit 33-10B transmits the alternating electric signal to the patient or the temperature detection signal (such as an analog temperature signal) detected by the corresponding one or more combinations of the temperature detection units 35B corresponding to the electrode units 33B is sampled and output to the corresponding ADC unit 52B respectively;The third bidirectional switch 55-3B is used to control the switching between the transmission of the alternating electric signal and the transmission of the temperature detection signal by the third dual-purpose signal line 19-3B of the corresponding electrode sheet 13B, thereby controlling the conduction of the electrode unit 33-11B to the electrode unit 33-13B in the third row group of the electrode sheet 13B and the conduction of the signal end of each temperature detection unit 35B corresponding to the electrode unit 33-11B to the electrode unit 33-13B in the third row group, and connecting with the corresponding first control switch 54-1B, the second control switch 54- 2B, the third control switch 54-3B cooperates to make the third row electrode unit 33-11B to the electrode unit 33-13B transmit the alternating electrical signal to the patient or make the temperature detection signal (such as the analog temperature signal) detected by the corresponding one or more combinations of the temperature detection units 35B corresponding to the electrode units 33B be sampled and output to the corresponding ADC unit 52B; the fourth two-way switch 55-4B does not correspond to any row group (not connected to any dual-purpose signal line), so there is no need to perform signal control through the fourth two-way switch 55-4B. ;

[0372] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 1 and will not be repeated here.

[0373] Embodiment 4:

[0374] In the tumor electric field treatment system 100B shown in Example 3, the electrode units 33B located at the ends of the 13 electrode units 33B in each electrode sheet 13B are not freely arranged. Fig. 20 Another tumor electric field treatment system 100C has the same main concept as the above-mentioned tumor electric field treatment system 100B, except that: the connection method of the connecting belt (unnumbered) in the electrode sheet 13C of the tumor electric field treatment system 100C is different, and the 13 electrode units 33C include 2 electrode units 33C at the free ends. Specifically, Fig. 20 In the electrode sheet 13C of the tumor electric field treatment system 100C shown, no connection belt is provided between the electrode unit 33C located in the first row and second column and the two electrode units 33C located in the first row and fourth column and the second row and first column; no connection belt is provided between the electrode unit 33C located in the fifth row and fourth column and the two electrode units 33C located in the fifth row and second column and the fourth row and fifth column; no connection belt is provided between the two electrode units 33C located in the second row and fifth column and the third row and fifth column; no connection belt is provided between the two electrode units 33C located in the second row and fifth column and the third row and fifth column. The connection belt (not shown) of the electrode sheet 100C is provided in this way to form a corresponding open space and free end for easy application.

[0375] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 3 and will not be repeated here.

[0376] Embodiment 5:

[0377] In the tumor electric field treatment system 100B shown in Example 3, the 13 electrode units 33 in each electrode sheet 13B are connected by 22 connecting strips. Fig.21 Another tumor electric field treatment system 100D has the same main concept as the above tumor electric field treatment system 100B, except that the 13 electrode units 33D in each electrode sheet 13D of the tumor electric field treatment system 100D are connected by 18 connecting strips. Specifically, Fig.21 In the electrode sheet 13D of the tumor electric field treatment system 100D shown, no connecting strip is provided between two adjacent electrode units 33D in the first row and the fifth row; no connecting strip is provided between two electrode units 33D in the first column of the second row and the third column of the second row; no connecting strip is provided between two electrode units 33D in the third column of the fourth row and the fifth column of the fourth row. The connecting strip (not shown) of the electrode sheet 100D is provided in this way to form a corresponding open space and free end for easy application.

[0378] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 3 and will not be repeated here.

[0379] Embodiment 6:

[0380] The difference from the tumor electric field treatment system 100B shown in Example 3 is that Fig. 22 Another tumor electric field therapy system 100E is described below. Its main concept is the same as that of the above-mentioned tumor electric field therapy system 100B, except that: each electrode sheet 13E of the tumor electric field therapy system 100E has different numbers of electrode units 33E contained in each row group and each column group in the circuit connection.

[0381] Fig. 22The figure is a schematic diagram of the circuit connection between the electrode sheet 13E and the adapter 20E of the tumor electric field treatment system 100E. The multiple electrode units 33E are configured into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13E is provided with 13 electrode units 33E, and the 13 electrode units 33E are arranged in the order of 1 to 13 in the circuit connection. The electrode units 33-1E to the electrode units 33-13E are divided into four row groups and four column groups, that is, the 13 electrode units 33E are arranged in four rows and four columns in the circuit connection. Each row of the first row group to the third row group includes 4 electrode units 33E, and the fourth row group includes 1 electrode unit 33E. The first column group includes 4 electrode units 33E, and the second column group to the fourth column group each include 3 electrode units 33E.

[0382] The electrode sheet 13E includes four grounding wires 18E, namely a first grounding wire 18-1E, a second grounding wire 18-2E, a third grounding wire 18-3E and a fourth grounding wire 18-4E. The first grounding wire 18-1E, the second grounding wire 18-2E, the third grounding wire 18-3E and the fourth grounding wire 18-4E are respectively arranged in one-to-one correspondence with the four column groups. Among the four column groups of the electrode sheet 13E, the first column group includes electrode unit 33-1E, electrode unit 33-5E, electrode unit 33-9E and electrode unit 33-13E, the second column group includes electrode unit 33-2E, electrode unit 33-6E and electrode unit 33-10E, the third column group includes electrode unit 33-3E, electrode unit 33-7E and electrode unit 33-11E, and the fourth column group includes electrode unit 33-4E, electrode unit 33-8E and electrode unit 33-12E. Specifically, the first grounding wire 18-1E is used to ground the grounding ends of the respective corresponding temperature detection units 35E in the electrode unit 33-1E, the electrode unit 33-5E, the electrode unit 33-9E, and the electrode unit 33-13E in the first column group; the second grounding wire 18-2E is used to ground the temperature detection units 35E connected in series in the electrode unit 33-1E and the electrode unit 33-2E, the temperature detection units 35E connected in series in the electrode unit 33-5E and the electrode unit 33-6E, and the temperature detection units 35E connected in series in the electrode unit 33-9E and the electrode unit 33-10E, respectively; the third grounding wire 18-3E is used to ground the electrode unit The temperature detection unit 35E connected in series from the electrode unit 33-1E to the electrode unit 33-3E, the temperature detection unit 35E connected in series from the electrode unit 33-5E to the electrode unit 33-7E, and the temperature detection unit 35E connected in series from the electrode unit 33-9E to the electrode unit 33-11E are grounded respectively; the fourth grounding line 18-4E is used to connect the temperature detection unit 35E connected in series from the electrode unit 33-1E to the electrode unit 33-4E, the temperature detection unit 35E connected in series from the electrode unit 33-5E to the electrode unit 33-8E, and the temperature detection unit 35E connected in series from the electrode unit 33-9E to the electrode unit 33-12E to the ground respectively. Of course, in some examples, the multi-path grounding line 18E may also include five-path grounding lines, wherein the fifth grounding line is not electrically connected to the ground terminal of any temperature detection unit, that is, the fifth grounding line does not short-circuit each corresponding temperature detection unit in any column group to the ground.

[0383] In this embodiment, the multiplexed signal line 19E includes a first dual-purpose signal line 19-1E, a second dual-purpose signal line 19-2E, a third dual-purpose signal line 19-3E and a fourth dual-purpose signal line 19-4E, which are respectively arranged in one-to-one correspondence with the four row groups of the electrode units 33E of the electrode sheet 13E. Specifically, the four electrode units 33E from the electrode unit 33-1E to the electrode unit 33-4E are connected in parallel to the second switching end 2 of the corresponding rectifying switching unit 16E, the temperature detection unit 35E of each electrode unit 33E is connected in series to the first switching end 1 of the corresponding rectifying switching unit 16E, and the fixed end 3 of the rectifying switching unit 16E is connected to the first dual-purpose signal line 19-1E; the four electrode units 33E from the electrode unit 33-5E to the electrode unit 33-8E are connected in parallel to the second switching end 2 of the corresponding rectifying switching unit 16E, the temperature detection unit 35E of each electrode unit 33E is connected in series to the first switching end 1 of the corresponding rectifying switching unit 16E, and the fixed end 3 of the rectifying switching unit 16E is connected Connected to the second dual-purpose signal line 19-2E; the four electrode units 33E from electrode unit 33-9E to electrode unit 33-12E are connected in parallel to the second switching end 2 of the corresponding rectifying switching unit 16E, and the temperature detection unit 35E of each electrode unit 33E is connected in series to the first switching end 1 of the corresponding rectifying switching unit 16E, and the fixed end 3 of the rectifying switching unit 16E is connected to the third dual-purpose signal line 19-3E; the electrode unit 33-13E is connected to the second switching end 2 of the corresponding rectifying switching unit 16E, and its corresponding temperature detection unit 35E is connected to the first switching end 1 of the corresponding rectifying switching unit 16E, and the fixed end 3 of the rectifying switching unit 16E is connected to the fourth dual-purpose signal line 19-4E.

[0384] Specifically, in this embodiment, the plurality of control switches 54E are respectively a first control switch 54-1E, a second control switch 54-2E, a third control switch 54-3E, a fourth control switch 54-4E and a fifth control switch 54-5E. The first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E and the fourth control switch 54-4E respectively control the closing or opening of the corresponding grounding line 18E of the same electrode sheet 13E. The first control switch 54-1E is used to control the closing or disconnection of the first grounding line 18-1E of the corresponding electrode sheet 13E, and can cooperate with the corresponding group of two-way switching switches 55E and the corresponding rectifying switching unit 16E to control the power on and off of each temperature detection unit 35E corresponding to the four electrode units 33E of the electrode unit 33-1E, electrode unit 33-5E, electrode unit 33-9E, and electrode unit 33-13E in the first column group of the electrode sheet 13E; the second control switch 54-2E is used to control the closing or disconnection of the second grounding line 18-2E of the electrode sheet 13E, and can cooperate with the corresponding group of two-way switching switches 55E and the corresponding rectifying switching unit 16E to control multiple electrode units in the first column group and the second column group of the electrode sheet 13E (the multiple electrode units can be: electrode unit 33-1E and electrode unit 33-2E, electrode unit 33-5E and electrode unit The temperature detection unit 35E corresponding to the electrode unit 33-6E, electrode unit 33-9E and electrode unit 33-10E) is powered on and off; the third control switch 54-3E is used to control the closing or disconnection of the third grounding line 18-3E of the electrode sheet 13E, and then cooperates with the corresponding group of two-way switching switches 55E and the corresponding rectifying switching unit to control the power on and off of each temperature detection unit 35E corresponding to multiple electrode units in the first column group, the second column group and the third column group of the electrode sheet 13E (the multiple electrode units can be respectively: electrode unit 33-1E to electrode unit 33-3E, electrode unit 33-5E to electrode unit 33-7E, electrode unit 33-9E to electrode unit 33-11E); the fourth control switch 54-4E is the same and will not be repeated here; the fifth control switch 54-5E is not connected to any grounding line, and the fifth control switch 54-5E is not used for signal control.

[0385] Taking the electrical connection between an electrode sheet 13E and an adapter 20E as an example, the multiple bidirectional switches 55E in the corresponding group of bidirectional switches 55E are respectively the first bidirectional switch 55-1E, the second bidirectional switch 55-2E, the third bidirectional switch 55-3E and the fourth bidirectional switch 55-4E. The first bidirectional switch 55-1E, the second bidirectional switch 55-2E, the third bidirectional switch 55-3E and the fourth bidirectional switch 55-4E respectively control the switching between the transmission of the alternating electric signal and the transmission of the temperature detection signal of the corresponding one of the multiplexed dual-purpose signal lines 19E of the same electrode sheet 13E. Specifically, the first bidirectional switch 55-1E is used to control the switching of the first dual-purpose signal line 19-1E of the corresponding electrode sheet 13E between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of each electrode unit 33E of the electrode unit 33-1E to the electrode unit 33-4E in the first row group of the electrode sheet 13E and the conduction of the signal end of each temperature detection unit corresponding to the electrode unit 33-1E to the electrode unit 33-4E in the first row group, and cooperating with the corresponding first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E, and the fourth control switch 54-4E, so that the first row of electrode units 33-1E to the electrode unit 33-4E transmit the alternating electric signal to the patient or the temperature detection signal (such as an analog temperature signal) detected by the corresponding one or more combinations of the temperature detection units 35E corresponding to the electrode units 33E is sampled and output to the corresponding ADC unit 52. E; The second bidirectional switch 55-2E is used to control the switching of the second dual-purpose signal line 19-2E of the corresponding electrode sheet 13E between transmitting the alternating electric signal and transmitting the temperature detection signal, thereby controlling the switching between the conduction of each electrode unit 33E from the electrode unit 33-5E to the electrode unit 33-8E in the second row group of the electrode sheet 13E and the conduction of the signal ends of each temperature detection unit 35E corresponding to the electrode unit 33-5E to the electrode unit 33-8E in the second row group, and cooperates with the corresponding first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E, and the fourth control switch 54-4E, so that the second row electrode unit 33-5E to the electrode unit 33-8E transmits the alternating electric signal to the patient or makes the temperature detection signal (such as the analog temperature signal) detected by the corresponding one or more combinations of the temperature detection units 35E corresponding to the electrode units 33E be sampled and output to the corresponding ADC unit 52E respectively;The third bidirectional switch 55-3E is used to control the switching of the third dual-purpose signal line 19-3E of the corresponding electrode sheet 13E between transmitting alternating electric signals and transmitting temperature detection signals, thereby controlling the switching between the conduction of each electrode unit 33E from the electrode unit 33-9E to the electrode unit 33-12E in the third row group of the electrode sheet 13E and the conduction of the signal ends of each temperature detection unit 35E corresponding to the electrode unit 33-9E to the electrode unit 33-12E in the third row group, and cooperating with the corresponding first control switch 54-1E, the second control switch 54-2E, the third control switch 54-3E, and the fourth control switch 54-4E, so that the third row of electrode units 33-9E to the electrode unit 33-12E transmit alternating electric signals to the patient or enable the corresponding one or more combinations of the temperature detection units 35E corresponding to these electrode units 33E to perform detection The temperature detection signals (such as analog temperature signals) measured by the fourth bidirectional switch 55-4E are sampled and output to the corresponding ADC unit 52E respectively; the fourth bidirectional switch 55-4E is used to control the switching between the transmission of the alternating electric signal and the transmission of the temperature detection signal by the fourth dual-purpose signal line 19-4E of the corresponding electrode sheet 13E, thereby controlling the switching between the conduction of the electrode units 33-13E in the fourth row group of the electrode sheet 13E and the conduction of the signal end of the temperature detection unit 35E corresponding to the electrode units 33-13E in the fourth row group, and cooperating with the corresponding first control switch 54-1E, so that the fourth row electrode units 33-13E transmit the alternating electric signal to the patient or the temperature detection signals (such as analog temperature signals) detected by the corresponding one or more combinations of the temperature detection units 35E corresponding to the electrode units 33E are sampled and output to the corresponding ADC unit 52E. ;

[0386] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 3 and will not be repeated here.

[0387] Embodiment 7:

[0388] The difference from the tumor electric field treatment system 100E shown in Example 6 is that Fig.23 Another tumor electric field therapy system 100F is described below. Its main concept is the same as that of the above-mentioned tumor electric field therapy system 100E, except that: each electrode sheet 13E of the tumor electric field therapy system 100F has different numbers of electrode units 33F contained in each row group and each column group in the circuit connection.

[0389] Fig.23The diagram is a circuit connection diagram of the electrode sheet 13F and the adapter 20F of the tumor electric field treatment system 100F. The multiple electrode units 33F are configured into multiple row groups and multiple column groups. In this embodiment, each electrode sheet 13F is provided with 13 electrode units 33F, and the 13 electrode units 33F are arranged in the order of 1 to 13 in the circuit connection. The electrode units 33-1F to the electrode units 33-13F are divided into four row groups and four column groups, that is, the 13 electrode units 33F are arranged in four rows and four columns in the circuit connection. The first row group includes 4 electrode units 33F, and each row of the second to fourth row groups includes 3 electrode units 33F, and each column of the first to third column groups includes 4 electrode units 33F, and the fourth column group includes 1 electrode unit 33F.

[0390] The electrode sheet 13F includes 4 grounding wires 18F, which are respectively a first grounding wire 18-1F, a second grounding wire 18-2F, a third grounding wire 18-3F and a fourth grounding wire 18-4F. The first grounding wire 18-1F, the second grounding wire 18-2F, the third grounding wire 18-3F and the fourth grounding wire 18-4F are respectively arranged in one-to-one correspondence with the four column groups. Of course, in some examples, the multi-path grounding wire 18F may also include five grounding wires, wherein the fifth grounding wire is not electrically connected to the ground terminal of any temperature detection unit, that is, the fifth grounding wire does not short-circuit each corresponding temperature detection unit in any column group to ground. The multiple control switches 54F are respectively a first control switch 54-1F, a second control switch 54-2F, a third control switch 54-3F, a fourth control switch 54-4F and a fifth control switch 54-5F. The first control switch 54-1F, the second control switch 54-2F, the third control switch 54-3F, and the fourth control switch 54-4F respectively control the closing or opening of the corresponding grounding line 18F of the same electrode sheet 13F. The fifth control switch 54-5F is not connected to any grounding line and is not used for signal control.

[0391] The multiplexed signal line 19F includes four dual-purpose signal lines, namely, a first dual-purpose signal line 19-1F, a second dual-purpose signal line 19-2F, a third dual-purpose signal line 19-3F and a fourth dual-purpose signal line 19-4F, which are respectively arranged in one-to-one correspondence with the four row groups of the electrode unit 33F. The plurality of bidirectional switches 55F are respectively a first bidirectional switch 55-1F, a second bidirectional switch 55-2F, a third bidirectional switch 55-3F and a fourth bidirectional switch 55-4F. The first bidirectional switch 55-1F, the second bidirectional switch 55-2F, the third bidirectional switch 55-3F and the fourth bidirectional switch 55-4F respectively control the switching between the transmission of the alternating electric signal and the transmission of the temperature detection signal of the corresponding one of the multiplexed signal lines 19F of the same electrode sheet 13F.

[0392] It is understandable that in other embodiments of the present application, such as Figures 23A to 23C As shown, each electrode sheet 13 may also include 12 electrode units 33, and the number of electrode units 33 included in each row group and each column group is different. Fig.23A As shown, the 12 electrode units 33I are arranged in the order of 1 to 12 in the circuit connection, and the electrode units 33-1I to 33-12I are divided into three row groups and five column groups, that is, the 12 electrode units 33I are arranged in three rows and five columns in the circuit connection, the first row group and the second row group each include 5 electrode units 33I, the third row group includes 2 electrode units 33I, the first column group to the second column group each include 3 electrode units 33I, and the third column group to the fifth column group each include 2 electrode units 33I. Fig. 23B As shown, the 12 electrode units 33J are arranged in the order of 1 to 12 in the circuit connection, and the electrode units 33-1J to 33-12J are divided into three row groups and four column groups, that is, the 12 electrode units 33J are arranged in three rows and four columns in the circuit connection, and the first row group to the third row group respectively include 4 electrode units 33J, and the first column group to the fourth column group each include 3 electrode units 33J. Fig.23C As shown, the 12 electrode units 33K are arranged in the order of 1 to 12 in the circuit connection, and the electrode units 33-1K to 33-12K are divided into four row groups and three column groups, that is, the 12 electrode units 33K are arranged in four rows and three columns in the circuit connection, and the first row group to the fourth row group include three electrode units 33K respectively, and the first column group to the third column group include four electrode units 33K each.

[0393] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 3 and will not be repeated here.

[0394] Embodiment 8:

[0395] The difference from the tumor electric field treatment systems 100B, 100C, 100D, 100E, and 100F shown in Examples 3 to 7 is that Fig.24 and Fig.25 Another tumor electric field therapy system 100G is described below, and its main concept is the same as that of the above-mentioned tumor electric field therapy system 100B, 100C, 100D, 100E or 100F, except that each electrode sheet 13G of the tumor electric field therapy system 100G includes 9 electrode units 33G.

[0396] Fig.25 for Fig.24 FIG. 1 is a schematic diagram showing the circuit connection between the electrode sheet 13G and the adapter 20G of the tumor electric field treatment system 100G.

[0397] The plurality of electrode units 33G are configured into a plurality of row groups and a plurality of column groups. In the present embodiment, each electrode sheet 13G is provided with 9 electrode units 33G, and the 9 electrode units 33G are arranged in the order of 1 to 9 in circuit connection, and the electrode units 33-1G to 33-9G are divided into three row groups and four column groups, that is, the 9 electrode units 33G are arranged in three rows and four columns in circuit connection, and each row from the first row group to the second row group includes 4 electrode units 33G, and the third row group includes 1 electrode unit 33G, the first column group includes 3 electrode units 33G, and each column from the second column group to the fourth column group includes 2 electrode units 33G.

[0398] The electrode sheet 13G includes 4 grounding wires 18G, which are the first grounding wire 18-1G, the second grounding wire 18-2G, the third grounding wire 18-3G and the fourth grounding wire 18-4G. The first grounding wire 18-1G, the second grounding wire 18-2G, the third grounding wire 18-3G and the fourth grounding wire 18-4G are respectively arranged in one-to-one correspondence with the four column groups of the electrode unit 33G. Of course, in some examples, the multi-path grounding wire 18G may also include five grounding wires, wherein the fifth grounding wire is not electrically connected to the ground terminal of any temperature detection unit, that is, the fifth grounding wire does not short-circuit each corresponding temperature detection unit in any column group to ground. The multiple control switches 54G are respectively the first control switch 54-1G, the second control switch 54-2G, the third control switch 54-3G, the fourth control switch 54-4G and the fifth control switch 54-5G. The first control switch 54-1G, the second control switch 54-2G, the third control switch 54-3G, and the fourth control switch 54-4G respectively control the closing or opening of the corresponding grounding line 18G of the same electrode sheet 13G. The fifth control switch 54-5G is not connected to any grounding line and is not used for signal control.

[0399] The multiplexed signal line 19G includes three dual-purpose signal lines, namely, a first dual-purpose signal line 19-1G, a second dual-purpose signal line 19-2G, and a third dual-purpose signal line 19-3G. The first dual-purpose signal line 19-1G, the second dual-purpose signal line 19-2G, and the third dual-purpose signal line 19-3G are respectively arranged in a one-to-one correspondence with the three row groups of the electrode unit 33G. Of course, in some examples, the multiplexed signal line 19G may also include four dual-purpose signal lines, wherein the fourth dual-purpose signal line is not electrically connected to the signal end of any temperature detection unit. The plurality of bidirectional switches 55G are respectively a first bidirectional switch 55-1G, a second bidirectional switch 55-2G, a third bidirectional switch 55-3G, and a fourth bidirectional switch 55-4G. The first bidirectional switch 55-1G, the second bidirectional switch 55-2G, and the third bidirectional switch 55-3G respectively control the switching of a corresponding dual-purpose signal line 19G in the multi-channel dual-purpose signal line 19G of the same electrode sheet 13G between transmitting alternating electrical signals and transmitting temperature detection signals. The fourth bidirectional switch 55-4G is not connected to any dual-purpose signal line, and the fourth bidirectional switch 55-4G is not used for signal control.

[0400] Among them, other contents in this embodiment are similar to those in the above-mentioned embodiment 1 and will not be repeated here.

[0401] Embodiment 9:

[0402] The difference from the tumor electric field treatment system 100G shown in Example 8 is that Fig.26 Another tumor electric field therapy system 100H is described below. Its main concept is the same as that of the above-mentioned tumor electric field therapy system 100G, except that: in the electrode sheets 13H of the tumor electric field therapy system 100H, the number of electrode units 33H contained in each row group and each column group in the circuit connection is different.

[0403] Fig.26 FIG. 1 is a schematic diagram showing the circuit connection between the electrode sheet 13H and the adapter 20H of the tumor electric field treatment system 100H.

[0404] The plurality of electrode units 33H are configured into a plurality of row groups and a plurality of column groups. In this embodiment, each electrode sheet 13H is provided with 9 electrode units 33H, and the 9 electrode units 33H are arranged in the order of 1 to 9 in circuit connection, and the electrode units 33-1H to 33-9H are divided into three row groups and three column groups, that is, the 9 electrode units 33H are arranged in three rows and three columns in circuit connection, and each row group includes 3 electrode units 33H, and each column group includes 3 electrode units 33H.

[0405] The electrode sheet 13H includes three grounding wires 18H, namely, a first grounding wire 18-1H, a second grounding wire 18-2H and a third grounding wire 18-3H. The first grounding wire 18-1H, the second grounding wire 18-2H and the third grounding wire 18-3H are respectively arranged in one-to-one correspondence with the three column groups of the electrode unit 33H. Of course, in some examples, the multi-channel grounding wire 18H may also include four or five grounding wires, wherein the fourth grounding wire and / or the fifth grounding wire are not electrically connected to the ground terminal of any temperature detection unit, that is, the fourth grounding wire and / or the fifth grounding wire do not short-circuit each corresponding temperature detection unit in any column group to ground. The multiple control switches 54H are respectively a first control switch 54-1H, a second control switch 54-2H, a third control switch 54-3H, a fourth control switch 54-4H and a fifth control switch 54-5H. The first control switch 54-1H, the second control switch 54-2H, and the third control switch 54-3H respectively control the closing or opening of the corresponding grounding line 18H of the same electrode sheet 13H. The fourth control switch 54-4H and the fifth control switch 54-5H are not connected to any grounding line, and the fourth control switch 54-4H and the fifth control switch 54-5H are not used for signal control.

[0406] The multiplexed signal line 19H includes three dual-purpose signal lines, namely, a first dual-purpose signal line 19-1H, a second dual-purpose signal line 19-2H and a third dual-purpose signal line 19-3H. The first dual-purpose signal line 19-1H, the second dual-purpose signal line 19-2H and the third dual-purpose signal line 19-3H are respectively arranged in one-to-one correspondence with the three row groups of the electrode unit 33H. Of course, in some examples, the multiplexed signal line 19H may also include four dual-purpose signal lines, wherein the fourth dual-purpose signal line is not electrically connected to the signal end of any temperature detection unit. The plurality of bidirectional switches 55H are respectively a first bidirectional switch 55-1H, a second bidirectional switch 55-2H, a third bidirectional switch 55-3H and a fourth bidirectional switch 55-4H. The first bidirectional switch 55-1H, the second bidirectional switch 55-2H and the third bidirectional switch 55-3H respectively control the switching between transmitting alternating electric signals and transmitting temperature detection signals of a corresponding one of the multi-channel dual-purpose signal lines 19H of the same electrode sheet 13H. The fourth bidirectional switch 55-4H is not connected to any dual-purpose signal line and is not used for signal control.

[0407] Among them, other contents in this embodiment are similar to those in the above-mentioned Embodiment 8 and will not be repeated here.

[0408] Embodiment 10:

[0409] The main concept of the above-mentioned tumor electric field treatment system 100 is that an alternating power line 57 is provided in each of the adapter 20 and the electric field generator 30 to control the synchronous change of the alternating electric signals of all electrode units 33 on an electrode sheet 13, such as the voltage or current rising or falling at the same time, and different alternating electric signals, such as voltages or currents of different magnitudes, cannot be applied to electrode units 33 of different rows at the same time. Figures 27 to 31 Another tumor electric field treatment system 100' is described below. Its main concept is the same as that of the above-mentioned tumor electric field treatment system 100, except that: each row group electrode unit 33' on the corresponding electrode sheet 13' in the adapter 20' and the electric field generator 30' of the tumor electric field treatment system 100' is provided with a corresponding alternating power line 57', so that different alternating electric signals, such as voltages or currents of different magnitudes, can be applied to different row groups of electrode units 33' at the same time.

[0410] Fig.28 FIG. 1 is a schematic diagram of a circuit connection between an electrode sheet 13 ′, an adapter 20 ′, and an electric field generator 30 ′ of another tumor electric field treatment system 100 ′ according to an embodiment of the present application. Fig.29 Schematic diagram of another electrode unit 33' according to an embodiment of the present application. The tumor electric field treatment system 100' includes: at least one pair of electrode sheets 13', an adapter 20' connected to the electrode sheets 13', and an electric field generator 30' connected to the adapter 20'.

[0411] The specific structure of the electrode sheet 13 ′ is the same as that of the electrode sheet 13 , and the structure of the temperature detection unit 35 ′ is also the same as that of the temperature detection unit 35 , which will not be described in detail here.

[0412] The specific structure of the adapter 20' is similar to the above-mentioned adapter 20, except that: Fig.28 and Fig.30 , the adapter 20' is provided with four alternating power lines 57' corresponding to each electrode sheet 13', and the four alternating power lines 57' are arranged one by one in correspondence with the four row group electrode units 33' of one electrode sheet 13', and each electrode sheet 13' is provided with a corresponding bidirectional switch 55' and a grounding switch 54', and both ends of the bidirectional switch 55' are electrically connected to a separate AC power line 57', so that the tumor electric field treatment system 100' can apply different alternating electrical signals, such as different voltages or currents, to different row group electrode units 33' in each electrode sheet 13' as needed.

[0413] The specific structure of the electric field generator 30' is similar to the above electric field generator 30, except that: Fig.28 and Fig.31A power switch 40' is provided for each alternating power line 57' connected between the AC signal generator 39' and the adapter 20' to individually control the on and off of the alternating electrical signal of each row group electrode unit 33' of each electrode sheet 13'.

[0414] Specifically, refer to Fig.28 and Fig.30 As shown, the adapter 20' includes: a first controller 51', multiple groups of ADC units 52' connected to the first controller 51', multiple groups of piezoelectric resistors 53' and multiple groups of control switches 54' corresponding to the multiple groups of ADC units 52', multiple groups of two-way switching switches 55' corresponding to the multiple groups of ADC units 52', a first communication unit 56', multiple alternating power lines 57' connected to each group of two-way switching switches 55' corresponding to each other, and a first power module 58' connected to the first communication unit 56', the first controller 51' and the multiple groups of ADC units 52' at the same time, and the first power module 58' provides a DC power supply VCC for each electronic component of the adapter 20'. The adapter 20' also includes multiple circuit lines (unnumbered), and the multiple circuit lines (unnumbered) are electrically connected to the multiple ground lines 18' and the multiple dual-purpose signal lines 19' in the substrate 31' of the electrode sheet 13' through the first cables 15' of the corresponding electrode sheet 13'. The multiple circuit lines (unnumbered) include multiple circuit lines 57' that transmit alternating electrical signals to the corresponding electrode sheets 13' and are electrically connected to different alternating power lines 57' respectively with the multiplexed signal lines 19' in the substrate 31' of the corresponding electrode sheets 13', multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiplexed signal lines 19' in the substrate 31' of the corresponding electrode sheets 13' and are used to supply power to the temperature detection units 35' of the electrode sheets 13' or to transmit the temperature detection signals of the electrode sheets 13', and multiple circuit lines (unnumbered) that are electrically connected one-to-one with the multiple ground lines 18' in the substrate 31' of the corresponding electrode sheets 13'. The number L of circuit lines electrically connected between the adapter 20' and one electrode sheet 13' is equal to the sum of the number of rows and the number of columns of the electrode units 33' of the electrode sheet 13' plus one; the number H of circuits electrically connected between the adapter 20' and X electrode sheets 13' is equal to X times the number of circuit lines electrically connected to a single electrode sheet 13', that is, H=XL=X*(M+N+1). The number of groups of control switches 54' and the number of groups of bidirectional switching switches 55' are both related to the number of electrode sheets 13'. The number of groups of control switches 54' is the same as the number of groups of bidirectional switching switches 55', and is not less than the number of electrode sheets 13'. Optionally, the number of groups of control switches 54' and bidirectional switching switches 55' are both the same as the number of electrode sheets 13'.

[0415] For example, each group of control switches 54' is provided with a plurality of control switches 54', and the plurality of control switches 54' are respectively connected to the adapter 20' and are respectively electrically connected to circuit lines (unnumbered) corresponding one by one to the multi-way grounding lines 18' of a corresponding electrode sheet 13', and are configured to control the conduction or disconnection of the multi-way grounding lines 18'. The circuit lines (unnumbered) of the multi-way grounding lines 18' that are electrically connected one by one to the electrode sheet 13' are grounded at one end close to the control switches 54'. The number of control switches 54' in each group of control switches 54' is related to the number of grounding lines 18' of the substrate 31' of the corresponding electrode sheet 13', and the two are equal in the present embodiment. Fig.28As shown, in this embodiment, the multiple control switches 54' in each group of control switches 54' are respectively a first control switch 54-1', a second control switch 54-2', a third control switch 54-3', a fourth control switch 54-4' and a fifth control switch 54-5'. The multiple control switches 54' in the same group control the closing or opening of the corresponding grounding line 18' of the same electrode sheet 13' one by one. The first control switch 54-1' is used to control the closing or disconnection of the first grounding line 18-1' of the corresponding electrode sheet 13', and can cooperate with the corresponding group of two-way switching switches 55' and the rectifying switching unit 16' to control the power on and off of each temperature detection unit 35' corresponding to the four electrode units 33' in the first column group of the electrode sheet 13', namely, the electrode unit 33-1', the electrode unit 33-6', the electrode unit 33-11', and the electrode unit 33-16'; the second control switch 54-2' is used to control the closing or disconnection of the second grounding line 18-2' of the electrode sheet 13', and can cooperate with the corresponding group of two-way switching switches 55' and the rectifying switching unit 16' to control the multiple electrode units in the first column group and the second column group of the electrode sheet 13' (the multiple electrode units can be respectively: electrode unit 33-1' and electrode unit 33-2', electrode unit 33-6' and electrode unit 33-7', electrode unit The temperature detection unit 35' corresponding to the electrode unit 33-11' and the electrode unit 33-12', the electrode unit 33-16' and the electrode unit 33-17') is powered on and off; the third control switch 54-3' is used to control the closing or disconnection of the third grounding line 18-3' of the electrode sheet 13', and then can cooperate with the corresponding group of two-way switching switches 55' and the rectifying switching unit 16' to control the power on and off of each temperature detection unit 35' corresponding to the multiple electrode units in the first column group, the second column group and the third column group of the electrode sheet 13' (the multiple electrode units can be respectively: electrode unit 33-1' to electrode unit 33-3', electrode unit 33-6' to electrode unit 33-8', electrode unit 33-11' to electrode unit 33-13', electrode unit 33-16' to electrode unit 33-18'); the fourth control switch 54-4' and the fifth control switch 54-5' are the same, and they are not repeated here. The control switch 54' can be a mechanical switch, such as a relay. The control switch 54' can also be an electronic switch, and each control switch 54' can be opened and closed by an additional first controller 51'.

[0416] In the present embodiment, the plurality of control switches 54' are all electronic switches. The first controller 51' is connected in communication with the plurality of control switches 54', and is used to sequentially and cyclically control the opening and closing states of the plurality of control switches 54' in each group of control switches 54', and then sequentially and individually conduct each of the plurality of grounding wires 18' of the corresponding electrode sheet 13' and cooperate with the switching of the corresponding two-way switching switch 55', so as to collect the temperature of the patient's body surface detected by all the temperature detection units 35' on the electrode sheet 13'. The number of each group of control switches 54' is not less than the number of grounding wires 18' of the substrate 31' of the corresponding electrode sheet 13'. In the present embodiment, the number of each group of control switches 54' is the same as the number of grounding wires 18' of the corresponding electrode sheet 13'.

[0417] Each set of two-way switching switches 55' is provided with a plurality of two-way switching switches 55', and the plurality of two-way switching switches 55' in each set are respectively connected to the adapter 20' and are respectively electrically connected to the circuit lines (not numbered) corresponding to the multiplex dual-purpose signal lines 19' of the corresponding electrode sheet 13'. The number of two-way switching switches 55' in each set of two-way switching switches 55' is related to the number of dual-purpose signal lines 19' of the substrate 31' of the corresponding electrode sheet 13', which is greater than or equal to the number of dual-purpose signal lines 19' of the substrate 31' of the corresponding electrode sheet 13', and in this embodiment, the two are equal. Each bidirectional switch 55' has two ends marked as 1 and 2. One end of multiple bidirectional switches 55' in the same group is electrically connected one by one to corresponding detection channels of multiple detection channels of a corresponding group of ADC units 52' through temperature sampling points (unnumbered), and two ends of each bidirectional switch 55' in the same group are electrically connected to corresponding different alternating power lines 57', and are configured to control the multi-channel dual-purpose signal line 19' to access the corresponding different alternating power lines 57' to transmit alternating electrical signals or to access the corresponding detection channels of the corresponding group of ADC units 52' to receive the temperature detection signals output by the temperature detection unit 35'.

[0418] like Fig.28As shown, taking the electrical connection between an electrode sheet 13' and an adapter 20' as an example, in this embodiment with 20 electrode units 33', the multiple two-way switches 55' in each group of two-way switches 55' are respectively a first two-way switch 55-1', a second two-way switch 55-2', a third two-way switch 55-3' and a fourth two-way switch 55-4'. The multiple two-way switches 55' in the same group respectively control the switching between the transmission of the alternating electric signal and the transmission of the temperature detection signal of the corresponding one of the two-way signal lines 19' of the same electrode sheet 13'. Specifically, the first bidirectional switch 55-1' is used to control the first dual-purpose signal line 19-1' of the corresponding electrode sheet 13' to switch between transmitting the alternating electric signal output by the alternating power line 57-1' and transmitting the temperature detection signal, thereby controlling the parallel conduction of each electrode unit 33' from the electrode unit 33-1' to the electrode unit 33-5' in the first row group of the electrode sheet 13' and the conduction of the signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-1' to the electrode unit 33-5' in the first row group. The switching is performed and cooperates with the corresponding first control switch 54-1', the second control switch 54-2', the third control switch 54-3', the fourth control switch 54-4', and the fifth control switch 54-5', so that the first row electrode unit 33-1' to the electrode unit 33-5' transmit a separate alternating electrical signal to the patient or the temperature detection signal (such as an analog temperature signal) detected by one or more combinations of the temperature detection units 35' corresponding to the electrode units 33' is sampled and output to the corresponding ADC unit 52'. The second bidirectional switch 55-2' is used to control the switching of the second dual-purpose signal line 19-2' of the corresponding electrode sheet 13' between the transmission of the alternating electric signal output by the alternating power line 57-2' and the transmission of the temperature detection signal, thereby controlling the parallel conduction of each electrode unit 33' from the electrode unit 33-6' to the electrode unit 33-10' in the second row group of the electrode sheet 13' and the conduction of the signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-6' to the electrode unit 33-10' in the second row group. The second row of electrode units 33-6' to 33-10' transmits a separate alternating electrical signal to the patient, or the temperature detection signals (such as analog temperature signals) detected by one or more combinations of the temperature detection units 35' corresponding to the electrode units 33' are sampled and output to the corresponding ADC unit 52';The third bidirectional switch 55-3' is used to control the switching of the third dual-purpose signal line 19-3' of the corresponding electrode sheet 13' between transmitting the alternating electric signal output by the alternating power line 57-3' and transmitting the temperature detection signal, thereby controlling the parallel conduction of each electrode unit 33' from the electrode unit 33-11' to the electrode unit 33-15' in the third row group of the electrode sheet 13' and the conduction of the signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-11' to the electrode unit 33-15' in the third row group. The third row of electrode units 33-11' to 33-15' transmits a separate alternating electrical signal to the patient or the temperature detection signals (such as analog temperature signals) detected by one or more combinations of the temperature detection units 35' corresponding to the electrode units 33' are sampled and output to the corresponding ADC unit 52'; The fourth bidirectional switch 55-4' is used to control the fourth dual-purpose signal line 19-4' of the corresponding electrode sheet 13' to switch between transmitting the alternating electric signal output by the alternating power line 57-4' and transmitting the temperature detection signal, thereby controlling the parallel conduction of each electrode unit 33' from the electrode unit 33-16' to the electrode unit 33-20' in the fourth row group of the electrode sheet 13' and the conduction of the signal end 35-2' of each temperature detection unit 35' corresponding to the electrode unit 33-16' to the electrode unit 33-20' in the fourth row group. The bidirectional switching switch 55' is switched and cooperates with the corresponding first control switch 54-1', second control switch 54-2', third control switch 54-3', fourth control switch 54-4', and fifth control switch 54-5', so that the fourth row electrode unit 33-16' to electrode unit 33-20' transmits a separate alternating electrical signal to the patient or the temperature detection signal (such as an analog temperature signal) detected by one or more combinations of the temperature detection units 35' corresponding to these electrode units 33' is sampled and output to the corresponding ADC unit 52'. The above-mentioned bidirectional switching switch 55' can be a mechanical switch, such as a relay. The bidirectional switching switch 55' can also be an electronic switch, and each bidirectional switching switch 55' can be switched by an additional first controller 51'. ;

[0419] In this embodiment, the plurality of sets of two-way switches 55' are all electronic switches. The first controller 51' is in communication connection with the plurality of sets of two-way switches 55', and is used to control the plurality of two-way switches 55' in each set of two-way switches 55' to switch between their respective ends 1 and 2, and to coordinate the closing or opening of the corresponding control switch 54', so as to continuously monitor the temperature of the patient's body surface detected by all the temperature detection units 35' on the electrode sheet 13' or transmit an alternating electrical signal to the patient.

[0420] In this embodiment, each group of ADC units 52' is electrically connected to one end of a plurality of bidirectional switching switches 55' in a corresponding group of bidirectional switching switches 55' through a multi-channel circuit line (not numbered) in the adapter 20', and is configured to receive a temperature detection signal transmitted by a multi-channel dual-purpose signal line 19' of a corresponding electrode sheet 13', and convert the temperature detection signal from an analog signal to a digital temperature signal. Each group of ADC units 52' includes a plurality of detection channels A, B, C, and D, and each detection channel A, B, C, and D is used to connect to a corresponding one of the dual-purpose signal lines 19' in the multi-channel dual-purpose signal line 19' through a corresponding bidirectional switching switch 55'. Fig.28 As shown, each group of ADC units 52' includes 4 detection channels A, B, C, and D, which are the first detection channel A, the second detection channel B, the third detection channel C, and the fourth detection channel D. The first detection channel A is connected to the first dual-purpose signal line 19-1' through one end of the first two-way switch 55-1', the second detection channel B is connected to the second dual-purpose signal line 19-2' through one end of the second two-way switch 55-2', the third detection channel C is connected to the third dual-purpose signal line 19-3' through one end of the third two-way switch 55-3', and the fourth detection channel D is connected to the fourth dual-purpose signal line 19-4' through one end of the fourth two-way switch 55-4'. Each detection channel A, B, C, and D is used to receive the temperature detection signal collected by the temperature detection unit 35' corresponding to the electrode unit 33' to which the corresponding dual-purpose signal line 19' is connected. In addition, each detection channel A, B, C, D is connected to a first power module 58' for providing detection voltage to the detection channel A, B, C, D via a corresponding voltage divider resistor 53' in the adapter 20'. The first power module 58' provides direct current.

[0421] In this embodiment, the first communication unit 56' is configured to obtain the digital temperature signals output by the multiple groups of ADC units 52' and send the digital temperature signals to the electric field generator 30'. The electric field generator 30' is also configured to control and adjust the voltage of the alternating electric signal provided to the multiple electrode units 33' of the electrode sheet 13' according to the received digital temperature signal. Exemplarily, when any of the multiple digital temperature signals received exceeds the preset threshold value, it means that the temperature detected by the temperature detection unit 35' corresponding to at least one electrode unit 33' in the electrode sheet 13' exceeds the preset threshold temperature (for example, 41°C, 42°C, etc.), at this time, the voltage of the alternating electric signal output by the electric field generator 30' can be appropriately reduced or stopped to avoid the electrode unit 33' of the electrode sheet 13' from being too high in temperature when the alternating electric signal is applied, causing low-temperature burns to the patient's skin. The above-mentioned preset threshold temperature and preset threshold value can be determined according to the human safety threshold value. The first communication unit 56' is controlled by the first controller 51' and transmits the digital temperature signals converted by the multiple groups of ADC units 52' in series. In this embodiment, the preset threshold temperature may be a value within the range of 36°C-45°C.

[0422] refer to Fig.28In this embodiment, the first power module 58' is electrically connected to the second power module 32' of the electric field generator 30', and is configured to supply power to the first controller 51', multiple groups of ADC units 52', and the first communication unit 56' of the adapter 20'. A first connector 60' is connected between each electrode sheet 13' and the adapter 20', and the first connector 60' is suitable for connecting the corresponding electrode sheet 13' to the adapter 20'. A second connector 70' is provided between the adapter 20' and the electric field generator 30', and the second connector 70' is suitable for connecting the electric field generator 30' to the adapter 20'. The adapter 20' also includes a second cable 25' connected to the second connector 70'. The second connector 70' includes a second plug 71' provided at an end of the second cable 25' away from the first controller 51' and a second socket 72' provided on the electric field generator 30'. The second plug 71' and the second socket 72' are push-type spring connectors, that is, the second connector 70' uses a connector to connect...

Claims

1. A control method for a tumor electric field treatment system, characterized in that: The tumor electric field treatment system comprises a first pair of electrode sheets and a second pair of electrode sheets, each of the electrode sheets comprises a plurality of electrode units and a plurality of temperature detection units, each of the electrode units can apply an alternating electric signal, each of the temperature detection units is arranged corresponding to one electrode unit to detect the temperature at the corresponding electrode unit, the plurality of electrode units are configured into at least two row groups and at least two column groups in terms of circuit connection, the grounding terminals of the temperature detection units in each of the column groups are connected to a grounding pin through a control switch, and the temperature detection units in each of the row groups are connected in series to form a temperature detection terminal, and the method comprises: When an alternating current signal is applied to the first pair of electrode sheets so as to generate an alternating electric field between the first pair of electrode sheets, the second pair of electrode sheets is controlled to perform temperature detection, wherein when the second pair of electrode sheets performs temperature detection, the temperature detection end corresponding to the target row group is switched to be connected to the corresponding temperature sampling point, and the control switches corresponding to the column group where each temperature detection unit in the target row group is located are controlled to be closed in sequence, so that the analog temperature signals detected by the corresponding one or more combinations of all the temperature detection units in the target row group are sampled separately based on the corresponding temperature sampling points, and the temperature at each electrode unit in the target row group is determined based on the separately sampled analog temperature signals.

2. The method according to claim 1, characterized in that For each of the electrode sheets, the temperature detection end corresponding to each of the row groups is connected to the first switching end of the corresponding rectifier switching unit, the second switching end of the rectifier switching unit corresponding to each of the row groups is respectively connected to each of the electrode units in the corresponding row group, the fixed end of the rectifier switching unit corresponding to each of the row groups is connected to the fixed end of the corresponding bidirectional switch through a dual-purpose signal line, the first end of the bidirectional switch corresponding to each of the rectifier switching units is the temperature sampling point of the corresponding row group, and the second end of the bidirectional switch corresponding to each of the rectifier switching units is connected to the alternating power line, wherein the first pair of electrode sheets is applied with an alternating current signal, including: The rectifying switching unit and the bidirectional switch corresponding to the first pair of electrode sheets are controlled to be linked so as to apply an alternating electric signal to the electrode units in the first pair of electrode sheets based on the alternating power line.

3. The method according to claim 2, characterized in that For each electrode sheet in the first pair of electrode sheets, when the control switches corresponding to each of the column groups are disconnected and any one of the dual-purpose signal lines is connected to the alternating power line, the second switching end of the rectifier switching unit corresponding to the dual-purpose signal line is controlled to be connected to the fixed end, so that each electrode unit in the row group corresponding to the dual-purpose signal line is applied with the alternating electrical signal based on the alternating power line.

4. The method according to claim 2, characterized in that: For each electrode sheet in the first pair of electrode sheets, when the control switches corresponding to each of the column groups are disconnected, the multi-channel target dual-purpose signal line is switched to be connected to the alternating power line, and the second switching end of each rectifier switching unit corresponding to the multi-channel target dual-purpose signal line is controlled to be connected to the fixed end, so that each electrode unit in the row group corresponding to the multi-channel target dual-purpose signal line is applied with the alternating electrical signal based on the alternating power line at the same time.

5. The method according to claim 2, characterized in that: For each electrode sheet in the first pair of electrode sheets, when the control switches corresponding to the column groups are all disconnected, the dual-purpose signal lines corresponding to at least two row groups are switched to connect to different alternating power lines, so that the respective electrode units in different row groups are applied with the alternating electrical signals based on different alternating power lines.

6. The method according to any one of claims 1 to 5, characterized in that For each electrode sheet in the second pair of electrode sheets, when the control switch corresponding to the column group where the first temperature detection unit connected to the temperature detection end in the target row group is located is closed, the analog temperature signal detected by the first temperature detection unit is sampled based on the corresponding temperature sampling point.

7. The method according to claim 6, characterized in that When the control switch corresponding to the column group where the second temperature detection unit adjacent to the first temperature detection unit in the target row group is located is closed, the analog temperature signal detected by the combination of the first temperature detection unit and the second temperature detection unit is sampled based on the corresponding temperature sampling point; When the control switch corresponding to the column group where the third temperature detection unit adjacent to the second temperature detection unit in the target row group is located is closed, the analog temperature signal detected by the combination of the first temperature detection unit, the second temperature detection unit and the third temperature detection unit is sampled based on the corresponding temperature sampling point; By analogy, when the control switch corresponding to the column group where the last temperature detection unit in the target row group is located is closed, the analog temperature signals detected by the combination of temperature detection units in the target row group are sampled based on the corresponding temperature sampling points.

8. The method according to claim 7, characterized in that Determining the temperature of each electrode unit in the target row group based on the respectively sampled analog temperature signals includes: Determining the temperature at a first electrode unit in the target row group based on the sampled analog temperature signal corresponding to the first temperature detection unit; Determine the temperature at the second electrode unit in the target row group based on the sampled analog temperature signal corresponding to the first temperature detection unit and the analog temperature signal corresponding to the combination of the first temperature detection unit and the second temperature detection unit; Determine the temperature at the third electrode unit in the target row group based on the sampled analog temperature signal corresponding to the combination of the first temperature detection unit and the second temperature detection unit, and the analog temperature signal corresponding to the combination of the first temperature detection unit, the second temperature detection unit, and the third temperature detection unit; By analogy, the temperatures at the fourth electrode unit to the last electrode unit in the target row group are determined.

9. The method according to claim 2, characterized in that: For each electrode sheet in the second pair of electrode sheets, the temperature detection end corresponding to the switching target row group is connected to the corresponding temperature sampling point, including: The rectifying switching unit corresponding to the target row group is controlled to be linked with the corresponding bidirectional switch, so that the temperature detection end corresponding to the target row group is connected to the corresponding temperature sampling point.

10. The method according to claim 9, characterized in that When the first end of the bidirectional switch corresponding to the target row group is connected to the fixed end, the fixed end of the rectifier switching unit linked to the bidirectional switch is connected to the first switching end.

11. A computer-readable storage medium, characterized in that: A computer program is stored thereon, and when the computer program is executed by a processor, the control method of the tumor electric field treatment system according to any one of claims 1-10 is implemented.

12. A tumor electric field treatment system, comprising a memory and a controller, characterized in that: The memory stores a computer program, which, when executed by the controller, implements the control method of the tumor electric field treatment system according to any one of claims 1-10.

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