A specific protein analysis and detection device

Through the sampling needle cleaning scheme driven by the lifting and rotating parts, the first connection part and the second connection part are used to achieve continuous cleaning of the inner wall of the sampling needle, solving the problem of poor cleaning of the inner wall of the absorption needle, and improving the accuracy of protein analysis and detection.

CN119986027BActive Publication Date: 2025-08-19上海逐典生物科技有限公司
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Patent Information

Application Number
CN202510451629.6
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2025-04-11
Publication Date
2025-08-19
Estimated Expiration
2045-04-11

AI Technical Summary

Technical Problem

In existing specific protein analysis and detection equipment, the cleaning effect of the inner wall of the aspiration needle is poor, resulting in contamination of the measurement reagent and affecting the protein analysis and detection results.

Method used

The driving rod and rocker arm are driven by the lifting and rotating parts. Through the cooperation of the first and second connection parts, the sampling needle is continuously cleaned by a micro-air pump and a water inlet pipe to ensure that the cleaning liquid enters and blows out of the inner wall of the sampling needle.

Benefits of technology

It improves the cleaning effect of the inner wall of the sampling needle, reduces the contamination of the assay reagents, and ensures the accuracy of the detection results of specific protein analysis.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present application discloses a specific protein analysis and detection device, which relates to the field of medical device technology. The device includes a housing, a reagent rack, a detection rack, a detection mechanism, a liquid collection mechanism, and a cleaning tube. The liquid collection mechanism includes a lifting component, a rotating component, a driving rod, a rocker arm, a micro air pump, and a sampling needle. The rocker arm is provided with a first connecting portion, the sampling needle is provided with a second connecting portion, a connecting pipe is connected between the first connecting portion and the second connecting portion, a first water inlet pipe is provided on the top wall of the housing, and a push rod is provided in the first water inlet pipe. The first water inlet pipe of the present application can supply cleaning liquid into the sampling needle through the first connecting portion, the connecting pipe, and the second connecting portion, so that the inner wall of the sampling needle can be continuously cleaned, thereby improving the cleaning effect of the inner wall of the sampling needle and making the results of the characteristic protein analysis and detection less susceptible to influence.
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Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a specific protein analysis and detection device. Background Art

[0002] Specific protein analysis equipment is a high-precision medical device based on modern optical, electronic, and computer technologies. It typically uses nephelometry to measure the content of specific proteins in blood and body fluids. Specific protein analysis equipment is widely used in hospital clinical laboratories, particularly in outpatient clinics, emergency departments, and hospitals at all levels.

[0003] Currently, the patent document with publication number CN220626398U discloses a fully automatic specific protein analyzer, including an upper cover, a lower cover, a reagent rack, a detection rack, a reagent suction device, a detection module, a cleaning tube and a circuit board. The reagent suction device sucks the test reagent on the reagent rack into the reagent suction needle, then drives the reagent suction needle to move into the detection module, and drops the test reagent into the detection module for automatic detection. The reagent suction needle after suction is placed in the cleaning tube, and the water inlet pipe continuously injects cleaning liquid into the cleaning tube and cleans the outer wall of the reagent suction needle. The reagent suction needle first sucks the cleaning liquid, then sprays the cleaning liquid and cleans the inner wall of the reagent suction needle. The water outlet pipe then discharges the waste liquid after cleaning in the cleaning tube.

[0004] When cleaning the aspiration needle, the reagent aspiration needle first absorbs the cleaning solution and then sprays the cleaning solution out, which will result in poor cleaning effect on the inner wall of the reagent aspiration needle, causing contamination of the assay reagent and thus affecting the protein analysis test results. Summary of the Invention

[0005] In order to improve the cleaning effect of the inner wall of the suction needle, the present application provides a specific protein analysis and detection device.

[0006] The specific protein analysis and detection device provided in this application adopts the following technical solution:

[0007] A specific protein analysis and detection device comprises a casing, a reagent rack is arranged in the casing, a detection rack is rotatably arranged in the casing, a detection mechanism is arranged in the casing below the detection rack, a liquid collection mechanism is arranged in the casing, a cleaning tube is arranged in the casing, the liquid collection mechanism comprises a lifting component, a rotating component, a driving rod, a rocker arm, a micro air pump and a sampling needle, the lifting component is arranged in the casing, the rotating component is arranged at the lifting end of the lifting component, the driving rod is arranged at the rotating end of the rotating component, the rocker arm is fixedly arranged at the top of the driving rod, the sampling needle is fixedly arranged on the side of the rocker arm bottom wall away from the driving rod, the micro air pump is arranged in the rocker arm and connected to the sampling needle; a first connecting part is arranged on the bottom wall of the rocker arm, and a second connecting part is arranged on the top of the outer side wall of the sampling needle. A connecting pipe is connected between the first connecting part and the second connecting part, and a first water inlet pipe is provided on the top wall of the casing. The first connecting part is movably connected to the first water inlet pipe, and a push rod is provided in the first water inlet pipe, and the top end of the push rod extends out of the first water inlet pipe; when the sampling needle moves into the cleaning pipe, the first connecting part moves to connect to the first water inlet pipe, the push rod extends into the first connecting part and pushes to open the first connecting part, the first connecting part connects the first water inlet pipe and the connecting pipe, the first water inlet pipe injects water into the connecting pipe, the water flow pushes the second connecting part to open, the second connecting part connects the connecting pipe and the sampling needle, and water flows into the sampling needle. When the sampling needle moves out of the cleaning pipe, the first connecting part closes and blocks the connecting pipe and the first water inlet pipe, and the second connecting part closes and blocks the connecting pipe and the sampling needle.

[0008] By adopting the above technical solution, the lifting component and the rotating component drive the driving rod to lift and rotate, and the driving rod then drives the sampling needle to lift and rotate through the rocker arm. The sampling needle first moves to the reagent rack, and the micro air pump sucks air so that the sampling needle absorbs the measurement reagent. The sampling needle then moves to the detection rack, and the micro air pump blows air so that the measurement reagent is injected into the detection rack. The detection mechanism performs specific protein analysis and detection. Then the sampling needle moves into the cleaning tube for cleaning. When the sampling needle enters the cleaning tube, the first connecting part moves to connect to the first water inlet pipe, the push rod extends into the first connecting part and opens the first connecting part. The first connecting part connects the first water inlet pipe and the connecting pipe. The first water inlet pipe injects water into the connecting pipe. The water flow pushes the second connecting part to open, and the second connecting part connects the connecting pipe and the sampling needle. At this time, water can enter the sampling needle through the second connecting part, and the micro air pump blows air again, so that the inner wall of the sampling needle can be continuously cleaned, thereby improving the cleaning effect of the inner wall of the sampling needle, so that the results of the characteristic protein analysis test are not easily affected.

[0009] Preferably, the first connecting part includes a first connecting sleeve, a first plug, a first support frame and a spring. The first connecting sleeve is fixedly arranged on the bottom wall of the rocker arm, the end of the connecting pipe is connected to the top of the first connecting sleeve, the first support frame is fixedly arranged in the first connecting sleeve, the first plug is slidably arranged at the bottom of the inner cavity of the first connecting sleeve, the spring is arranged in the first connecting sleeve, and the two ends of the spring are respectively connected to the first support frame and the first plug. The spring pushes the first plug to move to block the bottom opening of the first connecting sleeve, the bottom end of the first support frame moves to abut the first water inlet pipe, and the top end of the push rod moves to abut the first plug.

[0010] By adopting the above technical solution, during the liquid collection process by the sampling needle, the spring pushes the first plug to press against the bottom opening of the first connecting sleeve, thereby sealing the bottom opening of the first connecting sleeve. When the sampling needle descends into the cleaning tube, the rocker arm drives the first connecting sleeve to move downward, and the bottom end of the first connecting sleeve abuts the first water inlet pipe. At this time, the push rod extends into the first connecting sleeve and pushes the first plug to move in the first connecting sleeve, thereby opening the first connecting part.

[0011] Preferably, the second connecting part includes a second connecting sleeve, a second plug, a second support frame and a tension spring, one end of the second connecting sleeve is connected to the connecting pipe, and the other end is fixedly connected to the top of the outer wall of the sampling needle, the second support frame is fixedly arranged in the second connecting sleeve, and the second plug is slidably arranged in the inner cavity of the second connecting sleeve near one end of the sampling needle, the tension spring is arranged in the second connecting sleeve, and the two ends of the tension spring are respectively connected to the second support frame and the second plug, and the tension spring pulls the second plug to move and block the port of the second connecting sleeve close to the sampling needle.

[0012] By adopting the above technical solution, during the process of liquid collection by the sampling needle, the tension spring pulls the second plug to move and block the port of the second connecting sleeve close to the sampling needle, and then blocks the end of the second connecting sleeve. When the first connecting part is opened, water flows into the connecting pipe and pushes the second plug to move toward the sampling needle, thereby opening the second connecting part.

[0013] Preferably, a first sealing ring is provided on the top wall of the first water inlet pipe, and a second sealing ring is provided on the bottom wall of the first connecting sleeve.

[0014] By adopting the above technical solution, when the bottom end of the first connecting sleeve moves to abut the top end of the first water inlet pipe, the first sealing ring and the second sealing ring can seal the connection between the first connecting sleeve and the first water inlet pipe, thereby preventing the cleaning liquid from leaking.

[0015] Preferably, the first water inlet pipe includes a first tube body and a second tube body, the first tube body is arranged on the casing, the bottom end of the top rod is fixedly connected to the inner wall of the first tube body, the second tube body is slidably arranged on the top end of the first tube body along the axial direction of the first tube body, the first sealing ring is arranged on the top wall of the second tube body, and an elastic part is sleeved on the outside of the second tube body, the bottom end of the elastic part abuts the top end of the first tube body, and the top end of the elastic part abuts the second tube body, and the elastic part drives the second tube body to slide upward.

[0016] By adopting the above technical solution, the first connecting sleeve moves downward to contact the top of the second tube body. The first connecting sleeve drives the second tube body to move downward as it continues to descend. The second tube body moves and squeezes the elastic part. The elastic part shrinks and deforms and stores elastic potential energy. When the sampling needle is cleaned, the first water inlet pipe stops injecting water and the first connecting sleeve moves upward. At this time, the elastic part releases elastic potential energy and pushes the second tube body to move upward. The inner cavity volume of the first water inlet pipe is increased during the movement of the second tube body, so that the cleaning liquid is not easy to overflow from the first water inlet pipe.

[0017] Preferably, the top of the second tube body is concave, the bottom end of the first connecting sleeve is convex, the bottom end of the first connecting sleeve is inserted into the top end of the second tube body, and a water shield is provided on the outer wall of the top end of the second tube body. The water shield is located on the outside of the first connecting sleeve, and the top end of the water shield is expanded outward.

[0018] By adopting the above technical solution, when the seal between the first connecting sleeve and the second tube body leaks, the water shield can collect the leaked cleaning liquid so that the cleaning liquid will not leak onto the outer shell. When the first connecting sleeve is separated from the second tube body, the cleaning liquid in the water shield will flow back from the water shield into the second tube body.

[0019] Preferably, a first connecting rod is provided on the side of the first plug close to the first support frame, and a second connecting rod is slidingly provided in the connecting pipe along its own length direction, the connecting pipe and the second connecting sleeve are arranged along the same straight line direction, the second connecting rod extends into the second connecting sleeve and is fixedly connected to the second plug, and the ends of the second connecting rod and the first connecting rod close to each other are formed with wedge-shaped surfaces, and the wedge surfaces of the second connecting rod and the second connecting rod abut and fit each other, a water receiving pool is provided in the top wall of the casing, and the first water inlet pipe is provided in the water receiving pool.

[0020] When the cleaning fluid in the second connecting sleeve is discharged, the cleaning fluid in the second connecting sleeve is discharged from the cleaning tank, and the first connecting sleeve is moved to abut the first water inlet pipe, and the push rod pushes the first plug to move and open the first connecting part, and the first plug drives the first connecting rod to move, and the first connecting rod drives the second connecting rod to move and open the second connecting part. After the cleaning of the sampling needle is completed, the rocker arm moves upward a small distance. At this time, the bottom end of the first connecting sleeve is separated from the first water inlet pipe, and the push rod abuts the first plug and does not fully return to block the first connecting sleeve. The first plug drives the second plug through the first connecting rod and the second connecting rod and does not fully return to block the second connecting sleeve, so that the cleaning fluid in the second connecting sleeve, the connecting pipe and the first connecting sleeve can flow out from the opening at the bottom of the first connecting sleeve, so that no cleaning fluid will remain in the first connecting part, the connecting pipe and the second connecting part after the detection equipment is used up.

[0021] Preferably, a lifting member is provided in the casing, the lifting end of the lifting member is connected to the cleaning tube, a blocking block is provided in the cleaning tube, the top end of the blocking block is provided with a sharp corner, and the top end of the blocking block moves to block the bottom needle port of the sampling needle.

[0022] By adopting the above technical solution, when the cleaning liquid in the first connecting part, the connecting pipe and the second connecting part is cleared, the lifting member drives the cleaning pipe to move upward, and the cleaning pipe drives the blocking block to move upward and block the sampling needle. At this time, the micro air pump blows air, and the gas can enter the second connecting sleeve from the sampling needle, and then enter the first connecting sleeve from the connecting pipe, and finally be discharged from the bottom end of the first connecting sleeve, so that the residual cleaning liquid in the first connecting part, the connecting pipe and the second connecting part can be blown away, making the cleaning liquid removal more thorough.

[0023] In summary, this application includes at least one of the following beneficial technical effects:

[0024] 1. Utilizing the first water inlet pipe, when the sampling needle enters the cleaning tube, the first connecting portion moves to connect to the first water inlet pipe, the push rod extends into the first connecting portion and opens the first connecting portion, the first connecting portion connecting the first water inlet pipe and the connecting pipe, the first water inlet pipe injects water into the connecting pipe, the water flow pushes the second connecting portion to open, the second connecting portion connecting the connecting pipe and the sampling needle, at this time the water flow can enter the sampling needle through the second connecting portion, and the micro air pump then blows air, thereby continuously cleaning the inner wall of the sampling needle, improving the cleaning effect of the inner wall of the sampling needle, making the results of the characteristic protein analysis less susceptible to influence;

[0025] 2. With the help of the first tube body and the second tube body, the first connecting sleeve moves downward and contacts the top of the second tube body. As the first connecting sleeve continues to descend, it drives the second tube body downward. The second tube body moves and squeezes the elastic member, causing the elastic member to contract and deform and store elastic potential energy. When the sampling needle is cleaned, the first water inlet pipe stops filling with water, and the first connecting sleeve moves upward. At this time, the elastic member releases elastic potential energy and pushes the second tube body upward. During the movement of the second tube body, the inner cavity volume of the first water inlet pipe is increased, thereby preventing the cleaning liquid from overflowing from the first water inlet pipe.

[0026] 3. When the cleaning liquid in the first connecting part, the connecting pipe and the second connecting part is cleared through the sealing block, the lifting member drives the cleaning pipe to move upward, and the cleaning pipe drives the sealing block to move upward and seal the sampling needle. At this time, the micro air pump blows air, and the gas can enter the second connecting sleeve from the sampling needle, and then enter the first connecting sleeve from the connecting pipe, and finally be discharged from the bottom end of the first connecting sleeve, so that the residual cleaning liquid in the first connecting part, the connecting pipe and the second connecting part can be blown away, making the cleaning liquid removal more thorough. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 This is a schematic diagram of the overall structure of the specific protein analysis and detection device in Example 1 of the present application;

[0028] Figure 2 This is an exploded cross-sectional view of a portion of the structure of the specific protein analysis and detection device in Example 1 of the present application;

[0029] Figure 3 This is a partial structural cross-sectional view of the specific protein analysis and detection device in Example 1 of the present application;

[0030] Figure 4 For this application Figure 3 A in the middle is an enlarged schematic diagram;

[0031] Figure 5 For this application Figure 3 The enlarged schematic diagram of point B in the middle;

[0032] Figure 6 This is a partial structural cross-sectional view of the specific protein analysis and detection device in Example 2 of this application, highlighting the first water inlet pipe;

[0033] Figure 7 This is a partial structural cross-sectional view of the specific protein analysis and detection device in Example 3 of this application, highlighting the water receiving tank;

[0034] Figure 8 This is a partial structural cross-sectional view of the specific protein analysis and detection device in Example 3 of the present application, highlighting the first connecting rod and the second connecting rod;

[0035] Figure 9 This is a schematic diagram of a portion of the structure of the specific protein analysis and detection device in Example 3 of this application;

[0036] Figure 10 This is a partial structural cross-sectional view of the specific protein analysis and detection equipment in Example 3 of this application.

[0037] Figure numerals: 1, housing; 2, reagent rack; 3, detection rack; 4, detection mechanism; 5, liquid collection mechanism; 51, lifting component; 52, rotating component; 53, driving rod; 54, rocker arm; 55, micro air pump; 56, sampling needle; 6, cleaning tube; 7, first connecting part; 71, first connecting sleeve; 72, first plug; 73, first support frame; 74, spring; 8, second connecting part; 81, second connecting sleeve; 82, second plug; 83, second support frame; 84, tension spring; 9, first water inlet pipe; 91, first tube body; 92, second tube body; 10, connecting pipe; 11, push rod; 12, first sealing ring; 13, second sealing ring; 14, elastic Parts; 15. Water shield; 16. First connecting rod; 17. Second connecting rod; 18. Water receiving pool; 19. Lifting part; 20. Blocking block; 21. Round hole; 22. Square hole; 23. Driving part; 24. First cross bracket; 25. Step ring; 26. First water outlet pipe; 27. Second water inlet pipe; 28. Second water outlet pipe; 29. Right-angle elbow; 30. Second cross bracket; 31. Third cross bracket; 32. Lifting block; 33. Guide rod; 34. First water supply ring groove; 35. First through hole; 36. First water supply hole; 37. Second water supply ring groove; 38. Second through hole; 39. Second water supply hole; 40. Guide block; 41. Guide groove; 42. Fourth cross bracket. DETAILED DESCRIPTION

[0038] The following is combined with Figures 1-10 This application is described in further detail.

[0039] The embodiments of the present application disclose a specific protein analysis and detection device.

[0040] Example 1:

[0041] Reference Figure 1 and Figure 2A specific protein analysis and detection device includes a casing 1, on which two arc-shaped reagent racks 2 are symmetrically placed, and the measuring reagents are placed in the reagent racks 2 through test tubes. A circular detection rack 3 is rotatably mounted on the casing 1, and a plurality of circular holes 21 are equally spaced in the detection rack 3, and the circular holes 21 are used to place the test samples. The detection rack 3 is provided with a square hole 22 between each two adjacent circular holes 21, and the square hole 22 is used to place a cuvette. A driving member 23 is fixedly mounted in the casing 1, and the driving end of the driving member 23 is fixedly connected to the middle part of the bottom wall of the detection rack 3. In the present application, the driving member 23 can be selected as a servo motor, and the driving member 23 can drive the detection rack 3 to rotate.

[0042] A liquid extraction mechanism 5 is installed within the housing 1, located between the two reagent racks 2. This mechanism draws the assay reagent from the reagent racks 2 and transfers it to the detection rack 3. A detection mechanism 4 is installed within the housing 1, located below the detection rack 3. In this application, detection mechanism 4 can optionally be an optical detection module. During specific protein analysis and testing, the liquid extraction mechanism 5 draws the assay reagent and drips it into the empty cuvette within the square hole 22. It then draws the test sample from the circular hole 21 and drips it into the cuvette. Finally, the detection mechanism 4 performs the test.

[0043] Specifically, the liquid extraction mechanism 5 includes a lifting component 51, a rotating component 52, a drive rod 53, a rocker arm 54, a micro air pump 55, and a sampling needle 56. The lifting component 51 is mounted within the housing 1 and comprises a motor, a screw, and a slider. The motor drives the screw to rotate, which in turn drives the slider to move up and down. The rotating component 52 is mounted at the lifting end of the lifting component 51 and is a servo motor. The drive rod 53 is fixedly mounted at the rotating end of the rotating component 52.

[0044] The top end of the driving rod 53 passes through the top wall of the housing 1, and the driving rod 53 is located between the two reagent racks 2. One end of the rocker arm 54 is fixedly mounted on the top wall of the driving rod 53, and the micro air pump 55 is fixedly mounted in the end of the rocker arm 54 away from the driving rod 53. The sampling needle 56 is fixedly mounted on the bottom wall of the rocker arm 54 away from the driving rod 53, and the top end of the sampling needle 56 is connected to the output end of the micro air pump 55.

[0045] The rotating component 52 can drive the driving rod 53 to rotate, and the driving rod 53 can drive the sampling needle 56 to rotate and move through the rocker arm 54. When the sampling needle 56 moves to the top of the reagent rack 2 or the detection rack 3, the lifting component 51 drives the rotating component 52 to move up and down, and then drives the sampling needle 56 to move up and down. Then the micro air pump 55 inhales or blows air, so that the sampling needle 56 can absorb or discharge the reagent.

[0046] A cleaning tube 6 is installed within the housing 1, located between the detection rack 3 and the reagent rack 2, and directly below the circular trajectory of the sampling needle 56. A second water inlet pipe 27 and a second water outlet pipe 28 are connected to the side and bottom walls of the cleaning tube 6, respectively. The other ends of the second water inlet pipe 27 and the second water outlet pipe 28 pass through the housing 1 and are connected to the cleaning fluid supply device.

[0047] After the sampling needle 56 absorbs and discharges a reagent, the liquid collection mechanism 5 drives the sampling needle 56 to move into the cleaning pipe 6, and the second water inlet pipe 27 sprays cleaning liquid into the cleaning pipe 6 to clean the outer wall of the cleaning pipe 6. After cleaning, the second water outlet pipe 28 discharges the sewage in the cleaning pipe 6.

[0048] Reference Figure 1 、 Figure 2 、 Figure 3 and Figure 4 A first water inlet pipe 9 is installed in the housing 1, and the top end of the first water inlet pipe 9 extends out of the housing 1. The first water inlet pipe 9 is located on the side of the line connecting the cleaning pipe 6 and the driving rod 53, close to the cleaning pipe 6. A push rod 11 is fixedly installed in the first water inlet pipe 9 along its own axis, and the top end of the push rod 11 extends out of the first water inlet pipe 9.

[0049] A first connecting portion 7 is mounted on the bottom wall of the rocker arm 54, near the sampling needle 56. When the sampling needle 56 moves directly above the cleaning tube 6, the rocker arm 54 drives the first connecting portion 7 to move directly above the first water inlet pipe 9. A second connecting portion 8 is mounted on the top of the outer wall of the sampling needle 56, located within the rocker arm 54. A connecting pipe 10 is installed between the first connecting portion 7 and the second connecting portion 8.

[0050] Reference Figure 4 Specifically, the first connecting portion 7 includes a first connecting sleeve 71, a first plug 72, a first support frame 73 and a spring 74. The first connecting sleeve 71 is fixedly mounted on the bottom wall of the rocker arm 54 in the vertical direction, and one end of the connecting pipe 10 is connected to the top end of the first connecting sleeve 71. The first plug 72 is slidably mounted in the first connecting sleeve 71 along the axial direction of the first connecting sleeve 71. The first support frame 73 is fixedly mounted in the first connecting sleeve 71 and is located on the side of the first plug 72 close to the connecting pipe 10, and the first support frame 73 is a perforated frame plate. A first water supply annular groove 34 is provided on the inner side wall of the first connecting sleeve 71, a plurality of first through holes 35 are provided on the peripheral side wall of the first plug 72, and a first water supply hole 36 is provided on the side of the first plug 72 close to the first support frame 73. One end of the first water supply hole 36 is connected to the plurality of first through holes 35. The spring 74 is installed in the first water supply hole 36 of the first plug 72 , and an end of the spring 74 is connected to the first support frame 73 .

[0051] The spring 74 pushes the first plug 72 to move and press against the inner wall of the first connecting sleeve 71, so that the first plug 72 can block the first connecting sleeve 71. When the rocker arm 54 drives the sampling needle 56 down into the cleaning tube 6, the rocker arm 54 drives the first connecting sleeve 71 to move downward, and the top end of the push rod 11 first abuts against the first plug 72 and pushes the first plug 72 to slide into the first connecting sleeve 71, so that the first connecting part 7 is opened, and then the bottom wall of the first connecting sleeve 71 presses against the top wall of the first water inlet pipe 9. The first water inlet pipe 9 then injects water into the first connecting sleeve 71, and the water flows into the connecting pipe 10 through the first water supply ring groove 34, the first through hole 35, the first water supply hole 36 and the small hole on the first support plate in sequence, and then flows from the connecting pipe 10 into the second connecting part 8.

[0052] A first sealing ring 12 is fixedly embedded in the top wall of the first water inlet pipe 9, and a second sealing ring 13 is fixedly embedded in the bottom wall of the first connecting sleeve 71. The diameter of the first sealing ring 12 is smaller than the diameter of the second sealing ring 13. When the first connecting sleeve 71 abuts the first water inlet pipe 9, the first sealing ring 12 and the second sealing ring 13 seal the connection between the first connecting sleeve 71 and the first water inlet pipe 9, preventing the cleaning liquid from leaking.

[0053] Reference Figure 5 The second connecting portion 8 includes a second connecting sleeve 81, a second plug 82, a second support frame 83, and a tension spring 84. The second connecting sleeve 81 is fixedly mounted horizontally on the outer wall of the sampling needle 56. The second connecting sleeve 81 is located within the rocker arm 54, and the end of the second connecting sleeve 81 away from the sampling needle 56 is connected to the end of the connecting pipe 10 away from the first connecting sleeve 71. The second plug 82 is slidably mounted within the second connecting sleeve 81 along the axial direction of the second connecting sleeve 81. The second support frame 83 is fixedly mounted within the second connecting sleeve 81 and is located on the side of the second plug 82 close to the connecting pipe 10. The second support frame 83 is a perforated frame plate. A second water supply annular groove 37 is formed on the inner side wall of the second connecting sleeve 81. A plurality of second through holes 38 are formed on the peripheral side wall of the second plug 82. A second water supply hole 39 is formed on the side of the second plug 82 close to the second support frame 83. One end of the second water supply hole 39 is connected to the plurality of second through holes 38. The tension spring 84 is installed in the second water supply hole 39 of the second plug 82 , and both ends of the tension spring 84 are fixedly connected to the second plug 82 and the second support frame 83 respectively.

[0054] The tension spring 84 pulls the second plug 82 to move and press against the end wall of the second connecting sleeve 81, so that the second plug 82 can block the second connecting sleeve 81. When the first connecting part 7 is opened, the water flow in the connecting pipe 10 enters the second connecting sleeve 81 through the small hole on the second support plate, and the water flow then enters the second water supply hole 39 and pushes the second plug 82 to move away from the second connecting sleeve 81, so that the second connecting part 8 is opened. The water flow then flows out of the second connecting sleeve 81 through the second water supply hole 39, the second through hole 38 and the second water supply ring groove 37 in sequence, and the water flow flows from the second connecting sleeve 81 into the sampling needle 56. The micro air pump 55 then blows air, so that the inner wall of the sampling needle 56 can be continuously cleaned, thereby improving the cleaning effect of the inner wall of the sampling needle 56, so that the results of the characteristic protein analysis test are not easily affected.

[0055] Reference Figure 1 、 Figure 2 、 Figure 3 、 Figure 4 and Figure 5 The first water inlet pipe 9 and the second water inlet pipe 27 simultaneously clean the inner and outer walls of the sampling needle 56. After cleaning, the second water outlet pipe 28 discharges the wastewater in the cleaning pipe 6. The rocker arm 54 drives the sampling needle 56 and the first connecting sleeve 71 to move slightly upward, separating the first connecting sleeve 71 from the first water inlet pipe 9. Simultaneously, the push rod 11 separates from the first plug 72. At this time, the spring 74 pushes the first plug 72 to move and block the first connecting sleeve 71, and the tension spring 84 pulls the second plug 82 to move and block the second connecting sleeve 81. The micro air pump 55 then continues to blow air, quickly drying the sampling needle 56, making it easier to draw more sample liquid.

[0056] The implementation principle of a specific protein analysis and detection device in an embodiment of the present application is as follows: when analyzing and detecting a specific protein, the liquid collection mechanism 5 draws the assay reagent and drops it into the empty cuvette in the square hole 22, then draws the test sample in the circular hole 21 and drops it into the cuvette, and finally the detection mechanism 4 performs detection. After the sampling needle 56 absorbs and discharges a reagent, the liquid collection mechanism 5 drives the sampling needle 56 to move into the cleaning tube 6, and the second water inlet pipe 27 sprays cleaning liquid into the cleaning tube 6 and cleans the outer wall of the cleaning tube 6. At the same time, the first connecting part 7 moves to connect the first water inlet pipe 9, and the push rod 11 extends into the first connecting part 7 and opens the first connecting part 7. The first connecting part 7 connects the first water inlet pipe 9 and the connecting pipe 10. The first water inlet pipe 9 injects water into the connecting pipe 10, and the water flow pushes the second connecting part 8 to open. The second connecting part 8 connects the connecting pipe 10 and the sampling needle 56. At this time, the water flow can enter the sampling needle 56 through the second connecting part 8, and the micro air pump 55 blows air again, so that the inner wall of the sampling needle 56 can be continuously cleaned, thereby improving the cleaning effect of the inner wall of the sampling needle 56, so that the results of the characteristic protein analysis test are not easily affected.

[0057] Example 2:

[0058] Reference Figure 6 The difference between this embodiment and embodiment 1 is that the first water inlet pipe 9 includes a first tube body 91 and a second tube body 92. The first tube body 91 is fixedly installed in the housing 1, and the second tube body 92 is coaxially slidably installed on the top of the first tube body 91. The first sealing ring 12 is fixedly embedded in the top wall of the second tube body 92. The top rod 11 is located in the first tube body 91 and the second tube body 92, and the bottom end of the top rod 11 is fixedly connected to the inner wall of the first tube body 91 through a first cross bracket 24. An elastic member 14 is sleeved on the second tube body 92, and a step ring 25 is formed on the top end of the outer wall of the second tube body 92. The top end of the elastic member 14 abuts the bottom wall of the step ring 25, and the bottom end of the elastic member 14 abuts the top wall of the first tube body 91.

[0059] The elastic member 14 pushes the second tube body 92 upward through the step ring 25, at which point the top of the push rod 11 is located within the second tube body 92. When the rocker arm 54 drives the first connecting sleeve 71 downward, the bottom end of the first connecting sleeve 71 first contacts the top end of the second tube body 92. Subsequently, the first connecting sleeve 71 drives the second tube body 92 downward, and the push rod 11 then pushes the first plug 72 to move and open the first connecting portion 7. When the rocker arm 54 drives the first connecting sleeve 71 upward, the elastic member 14 pushes the second tube body 92 upward, and the push rod 11 first separates from the first plug 72. When the second tube body 92 rises to its highest position and covers the top end of the push rod 11, the second tube body 92 separates from the first connecting sleeve 71. This prevents the cleaning fluid from leaking when the first connecting portion 7 is opened and closed.

[0060] Four guide blocks 40 are fixedly mounted on the outer sidewall of the second tube body 92 at equal intervals along its circumference. Four guide grooves 41 are formed on the inner sidewall of the first tube body 91 at equal intervals along its circumference. The four guide blocks 40 are slidably mounted within the four guide grooves 41 along the axis of the first tube body 91. The guide blocks 40 slide within the guide grooves 41, thereby limiting the movement of the second tube body 92 and preventing it from sliding out of the first tube body 91.

[0061] The bottom end of the first connecting sleeve 71 is set at a sharp angle, and the top end of the second tube body 92 is set inwardly, and the sharp angle of the bottom of the first connecting sleeve 71 is adapted to be inserted into the concave area at the top of the second tube body 92. A water shield 15 is fixedly installed at the top end of the outer wall of the second tube body 92. When the bottom end of the first connecting sleeve 71 is inserted into the top end of the second tube body 92, the water shield 15 is arranged to cover the outside of the first connecting sleeve 71. The top end of the water shield 15 is set to expand outward, and the diameter of the water shield 15 gradually increases from bottom to top.

[0062] When the seal between the first connecting sleeve 71 and the second tube body 92 leaks, the water shield 15 can collect the leaked cleaning liquid so that the cleaning liquid will not leak onto the outer shell. When the first connecting sleeve 71 is separated from the second tube body 92, the cleaning liquid in the water shield 15 will flow back from the water shield 15 into the second tube body 92, so that the cleaning liquid will not leak onto the casing 1.

[0063] The implementation principle of Example 2 of the present application is as follows: the first connecting sleeve 71 moves downward to contact the top of the second tube body 92, and the first connecting sleeve 71 continues to move downward, driving the second tube body 92 to move downward, and the second tube body 92 moves and squeezes the elastic part 14. The elastic part 14 shrinks and deforms and stores elastic potential energy. When the sampling needle 56 completes cleaning, the first water inlet pipe 9 stops injecting water, and the first connecting sleeve 71 moves upward. At this time, the elastic part 14 releases elastic potential energy and pushes the second tube body 92 to move upward. During the movement of the second tube body 92, the inner cavity volume of the first water inlet pipe 9 is increased, so that the cleaning liquid is not easy to overflow from the first water inlet pipe 9.

[0064] Example 3:

[0065] Reference Figure 7 The difference between this embodiment and embodiment 1 is that a water receiving pool 18 is embedded and fixedly installed on the top wall of the first housing 1, a first water outlet pipe 26 is connected to the bottom wall of the water receiving pool 18, the first water inlet pipe 9 passes through the water receiving pool 18, and the top end of the first water inlet pipe 9 extends out of the water receiving pool 18.

[0066] Reference Figure 8 A right-angle elbow 29 is fixedly installed on the top of the first connecting sleeve 71. The end of the right-angle elbow 29 away from the first connecting sleeve 71 is connected to the end of the connecting pipe 10 away from the second connecting sleeve 81, and the axes of the connecting pipe 10 and the second connecting sleeve 81 are on the same straight line.

[0067] A first connecting rod 16 is fixedly mounted in the first water supply hole 36 of the first plug 72. The first connecting rod 16 passes through the hole of the first support frame 73 and is slidably mounted in the first connecting sleeve 71 and the right-angle elbow 29 via two second cross brackets 30. A second connecting rod 17 is fixedly mounted in the second water supply hole 39 of the second plug 82. The second connecting rod 17 passes through the second support frame 83 and is slidably mounted in the second connecting sleeve 81, the connecting pipe 10, and the right-angle elbow 29 via two third cross brackets 31. The ends of the second connecting rod 17 and the first connecting rod 16 that are close to each other are both formed with wedge-shaped surfaces. The wedge-shaped surfaces of the second connecting rod 17 and the second connecting rod 17 abut and fit against each other within the right-angle elbow 29.

[0068] When the push rod 11 pushes the first plug 72 to move and open the first connecting part 7, the first plug 72 drives the first connecting rod 16 to move, the first connecting rod 16 drives the second connecting rod 17 to move through the wedge surface, and the second connecting rod 17 drives the second plug 82 to move and open the second connecting part 8, so that the first connecting part 7 and the second connecting part 8 can be opened synchronously.

[0069] Reference Figure 7 and Figure 8 When the testing equipment completes testing and cleaning, some cleaning fluid will remain in the first connecting sleeve 71, the connecting pipe 10, and the second connecting sleeve 81. At this time, the rocker arm 54 drives the first connecting sleeve 71 to move slightly upward, separating the bottom end of the first connecting sleeve 71 from the first water outlet pipe 26. However, the push rod 11 and the first plug 72 are not separated at this time, so that the first connecting part 7 and the second connecting part 8 remain in the open state, thereby being able to remove the cleaning fluid remaining in the first connecting sleeve 71, the connecting pipe 10, and the second connecting sleeve 81. The cleaning fluid flows into the water receiving tank 18 and is discharged from the first water outlet pipe 26.

[0070] Reference Figure 8 、 Figure 9 and Figure 10 A lifting member 19 is fixedly installed in the housing 1. A lifting block 32 is fixedly installed at the lifting end of the lifting member 19. The lifting block 32 is fixedly connected to the cleaning tube 6. A guide rod 33 is fixedly installed in the housing 1 in the vertical direction. The lifting block 32 is slidably installed on the guide rod 33 in the vertical direction. A blocking block 20 is fixedly installed in the middle and lower part of the inner cavity of the cleaning tube 6 through a fourth cross bracket 42. The top corner of the blocking block 20 is set, and the top of the blocking block 20 is directly below the sampling needle 56. In this application, the lifting member 19 can be selected as a cylinder, and the blocking block 20 is a flexible block.

[0071] After the cleaning liquid in the first connecting sleeve 71, the connecting pipe 10 and the second connecting sleeve 81 is cleared, the lifting member 19 drives the cleaning tube 6 to move upward through the lifting block 32, and the cleaning tube 6 drives the blocking block 20 to move upward and blocks the sampling needle 56. At this time, the micro air pump 55 blows air, and the gas can enter the second connecting sleeve 81 from the sampling needle 56, and then enter the first connecting sleeve 71 from the connecting pipe 10, and finally blow out from the bottom end of the first connecting sleeve 71, so that the remaining cleaning liquid in the first connecting sleeve 71, the connecting pipe 10 and the second connecting sleeve 81 can be blown away, so that the cleaning liquid can be removed more thoroughly.

[0072] The working principle of Example 3 of the present application is as follows: when the detection device completes detection and cleaning, some cleaning fluid will remain in the first connecting sleeve 71, the connecting pipe 10, and the second connecting sleeve 81. At this time, the rocker arm 54 drives the first connecting sleeve 71 to move slightly upward, so that the bottom end of the first connecting sleeve 71 is separated from the first water outlet pipe 26. However, at this time, the push rod 11 and the first plug 72 are not separated, so that the first connecting part 7 and the second connecting part 8 are still in the open state, thereby being able to drain the cleaning fluid remaining in the first connecting sleeve 71, the connecting pipe 10, and the second connecting sleeve 81.

[0073] The above are merely optional embodiments of the present disclosure and are not intended to limit the present disclosure. Those skilled in the art will readily appreciate that the present disclosure may be modified and varied in various ways. Any modifications, equivalent substitutions, improvements, and the like made within the spirit and principles of the present disclosure shall be included within the scope of protection of the present disclosure.

Claims

1. A specific protein analysis and detection device, comprising a housing (1), a reagent rack (2) disposed in the housing (1), a detection rack (3) rotatably disposed in the housing (1), a detection mechanism (4) disposed below the detection rack (3) in the housing (1), a liquid collection mechanism (5) disposed in the housing (1), and a cleaning tube (6) disposed in the housing (1), characterized in that: The liquid collection mechanism (5) comprises a lifting component (51), a rotating component (52), a driving rod (53), a rocker arm (54), a micro air pump (55) and a sampling needle (56); the lifting component (51) is arranged in the housing (1); the rotating component (52) is arranged at the lifting end of the lifting component (51); the driving rod (53) is arranged at the rotating end of the rotating component (52); the rocker arm (54) is fixedly arranged at the top end of the driving rod (53); the sampling needle (56) is fixedly arranged on the side of the bottom wall of the rocker arm (54) away from the driving rod (53); the micro air pump (55) is arranged in the rocker arm (54) and connected to the sampling needle (56); A first connecting portion (7) is provided on the bottom wall of the rocker arm (54), a second connecting portion (8) is provided on the top of the outer wall of the sampling needle (56), a connecting pipe (10) is connected between the first connecting portion (7) and the second connecting portion (8), a first water inlet pipe (9) is provided on the top wall of the housing (1), the first connecting portion (7) is movably connected to the first water inlet pipe (9), a push rod (11) is provided in the first water inlet pipe (9), and the top end of the push rod (11) extends out of the first water inlet pipe (9); When the sampling needle (56) moves into the cleaning pipe (6), the first connecting part (7) moves to connect to the first water inlet pipe (9), the push rod (11) extends into the first connecting part (7) and pushes the first connecting part (7) to open, the first connecting part (7) connects the first water inlet pipe (9) and the connecting pipe (10), the first water inlet pipe (9) injects water into the connecting pipe (10), the water flow pushes the second connecting part (8) to open, the second connecting part (8) connects the connecting pipe (10) and the sampling needle (56), the water flow enters the sampling needle (56), when the sampling needle (56) moves out of the cleaning pipe (6), the first connecting part (7) closes and blocks the connecting pipe (10) and the first water inlet pipe (9), the second connecting part (8) closes and blocks the connecting pipe (10) and the sampling needle (56).

2. A specific protein analysis and detection device according to claim 1, characterized in that: The first connecting portion (7) comprises a first connecting sleeve (71), a first plug (72), a first support frame (73) and a spring (74); the first connecting sleeve (71) is fixedly arranged on the bottom wall of the rocker arm (54); the end of the connecting pipe (10) is connected to the top end of the first connecting sleeve (71); the first support frame (73) is fixedly arranged in the first connecting sleeve (71); the first plug (72) is slidably arranged at the bottom of the inner cavity of the first connecting sleeve (71); the spring (74) is arranged in the first connecting sleeve (71); the two ends of the spring (74) are respectively connected to the first support frame (73) and the first plug (72); the spring (74) pushes the first plug (72) to move and block the bottom opening of the first connecting sleeve (71); the bottom end of the first support frame (73) moves to abut against the first water inlet pipe (9), and the top end of the push rod (11) moves to abut against the first plug (72).

3. The specific protein analysis and detection device according to claim 2, characterized in that: The second connecting portion (8) includes a second connecting sleeve (81), a second plug (82), a second support frame (83) and a tension spring (84). One end of the second connecting sleeve (81) is connected to the connecting pipe (10), and the other end is fixedly connected to the top of the outer wall of the sampling needle (56). The second support frame (83) is fixedly arranged in the second connecting sleeve (81). The second plug (82) is slidably arranged in the inner cavity of the second connecting sleeve (81) near one end of the sampling needle (56). The tension spring (84) is arranged in the second connecting sleeve (81). The two ends of the tension spring (84) are respectively connected to the second support frame (83) and the second plug (82). The tension spring (84) pulls the second plug (82) to move and block the port of the second connecting sleeve (81) near the sampling needle (56).

4. The specific protein analysis and detection device according to claim 2, characterized in that: A first sealing ring (12) is provided on the top wall of the first water inlet pipe (9), and a second sealing ring (13) is provided on the bottom wall of the first connecting sleeve (71).

5. The specific protein analysis and detection device according to claim 4, characterized in that: The first water inlet pipe (9) comprises a first tube body (91) and a second tube body (92), wherein the first tube body (91) is arranged on the housing (1), the bottom end of the top rod (11) is fixedly connected to the inner wall of the first tube body (91), the second tube body (92) is slidably arranged on the top end of the first tube body (91) along the axial direction of the first tube body (91), the first sealing ring (12) is arranged on the top wall of the second tube body (92), and an elastic member (14) is sleeved on the outer side of the second tube body (92), the bottom end of the elastic member (14) abuts against the top end of the first tube body (91), and the top end of the elastic member (14) abuts against the second tube body (92), and the elastic member (14) drives the second tube body (92) to slide upward.

6. The specific protein analysis and detection device according to claim 5, characterized in that: The top of the second tube body (92) is concave, the bottom end of the first connecting sleeve (71) is convex, the bottom end of the first connecting sleeve (71) is inserted into the top end of the second tube body (92), and a water shield (15) is provided on the outer side wall of the top end of the second tube body (92). The water shield (15) is located outside the first connecting sleeve (71), and the top end of the water shield (15) is expanded outward.

7. The specific protein analysis and detection device according to claim 3, characterized in that: A first connecting rod (16) is provided on one side of the first plug (72) close to the first support frame (73), a second connecting rod (17) is provided in the connecting pipe (10) for sliding along its own length direction, the connecting pipe (10) and the second connecting sleeve (81) are arranged along the same straight line direction, the second connecting rod (17) extends into the second connecting sleeve (81) and is fixedly connected to the second plug (82), the ends of the second connecting rod (17) and the first connecting rod (16) close to each other are formed with wedge-shaped surfaces, the wedge-shaped surfaces of the first connecting rod (16) and the second connecting rod (17) are in contact with each other, a water receiving pool (18) is provided in the top wall of the casing (1), and the first water inlet pipe (9) is provided in the water receiving pool (18).

8. The specific protein analysis and detection device according to claim 7, characterized in that: A lifting member (19) is provided in the housing (1), and a lifting end of the lifting member (19) is connected to a cleaning tube (6). A blocking block (20) is provided in the cleaning tube (6), and a top end of the blocking block (20) is provided with a sharp corner, and the top end of the blocking block (20) moves to block the bottom needle opening of the sampling needle (56).

Citation Information

Patent Citations

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