Bactericidal preparation and application thereof

Abstract

The invention belongs to the field of bactericides, and relates to a bactericide of a triazolinone ether compound (as shown in a general formula I) and application of the bactericide. A compound as shown in the general formula I is used as an active component and is mixed with a pesticide acceptable carrier, and the weight percentage of the active component is 1-99%. The bactericide composition disclosed by the invention has the characteristics of good wetting, spreading and permeation of the liquid medicine on a target, less rebound of the liquid medicine on the target, large liquid holdup, large deposition amount, small evaporation, large absorption rate, high biological activity, safety to crops and the like, and is an ideal bactericide variety for preventing and treating wheat powdery mildew, wheat rust and other diseases at home and abroad at present. # imgabs0 #

Description

Technical Field

[0001] The present invention belongs to the technical field of agricultural fungicides, and relates to a fungicide containing a triazolinone ether compound (as shown in general formula I) and its application. Background Art

[0002] Wheat is an important food crop in China, and its planting area (23.72 million hectares) is extensive. Among them, wheat powdery mildew and rust not only seriously damage crops but also break out quickly. If not properly controlled in time, the growth of the affected plants will be severely affected, and ultimately the yield will be greatly reduced. The triazolinone ether compound (as shown in general formula I) disclosed in Chinese Patent (Patent No.: CN 102336744 B) can be used to control diseases caused by various diseases such as Oomycetes, Basidiomycetes, Ascomycetes, and Deuteromycetes on various plants, has high biological activity, and has excellent control effects on diseases such as wheat powdery mildew and rust. However, this patent only generally mentions in the specification that the active ingredient triazolinone ether compound (as shown in general formula I) can be processed into dry powder, emulsifiable concentrate, wettable powder, microemulsion, paste, granule, suspension, water dispersible granule, etc., but there are no specific biological activity determination results. Moreover, the technical drug is first dissolved with an organic solvent (such as acetone), and then diluted with a 0.1% aqueous solution of Tween 80 to a solution with the required concentration as the spraying liquid for use, but this has great defects: on the one hand, it is prepared and used immediately, which is relatively troublesome to apply, uses a large amount of organic solvent, has a great impact on the environment, and has a high cost; on the other hand, the diluted liquid medicine needs to be used immediately, and the active ingredient is easily precipitated after long-term placement, which is not conducive to transportation and storage and is difficult to meet the actual application needs. In particular, the most important problem in the fungicide industry at present is how to select a suitable adjuvant system for the active ingredient to better control the dynamic surface tension and droplet size of the spray liquid medicine, so that the liquid medicine drifts less, evaporates slowly, spreads, wets, adheres well on the target, has a long residence time, thereby improving the utilization rate of pesticides, and at the same time reducing the phytotoxicity problem of surrounding crops caused by drift. Summary of the Invention

[0003] The purpose of the present invention is to provide a bactericidal preparation taking a triazolinone ether compound (as shown in general formula I) as an active ingredient and its usage method.

[0004] In order to achieve the above purpose, the technical solution adopted by the present invention is as follows:

[0005] A fungicide, which is prepared by mixing a compound shown in general formula I as an active ingredient with a pesticide-acceptable carrier, and the weight percentage content of the active ingredient is 1-99%.

[0006]

[0007] Wherein:

[0008] Q is selected from Q1 or Q2 as shown below:

[0009]

[0010] Q is selected from Q1 or Q2;

[0011] When Q is selected from Q1: R 1 is selected from hydrogen, halogen, cyano, nitro, CH 2 CN, C 1 -C 6 alkyl, halo-C 1 -C 6 alkyl or C 3 -C 6 cycloalkyl, R 2 is selected from hydrogen, C 1 -C 6 alkyl or halo-C 1 -C 6 alkyl;

[0012] When Q is selected from Q2: R 1 is selected from halogen, C 1 -C 6 alkyl, halo-C 1 -C 6 alkyl or C 3 -C 6 cycloalkyl, R 2 is selected from C 1 -C 6 alkyl or halo-C 1 -C 6 alkyl;

[0013] R 3 is selected from halogen, cyano, nitro, hydroxy, C 1 -C 4 alkyl, halo-C 1 -C 3 alkyl, C 1 -C 3 alkoxy, halo-C 1 -C 3 alkoxy, C 1 -C 3 alkylthio, C 1 -C 3 alkylsulfonyl, phenyl or phenoxy which is unsubstituted or substituted by 1 - 5 groups independently selected from the following: fluorine, chlorine, bromine, nitro, cyano, trifluoromethyl, C 1 -C 3 alkyl, C 1 -C 3 alkoxy or halo-C 1 -C 3 alkoxy;

[0014] R 4 、R 5 may be the same or different and are each independently selected from hydrogen, halogen, nitro, cyano, C 1 -C 6 alkyl, halo-C 1 -C 6 alkyl, C 1 -C 6 alkoxy, halo-C 1 -C 6 alkoxy, C 1 -C 6 alkylthio, C 1 -C 6 alkylsulfonyl, phenyl, pyridyl, furyl, thienyl or thiazolyl which is unsubstituted or substituted by 1-5 groups independently selected from the following: halogen, cyano, nitro, CO 2 (C 1 -C 4 alkyl), C 1 -C 6 alkyl, halo-C 1 -C 6 alkyl, C 1 -C 6 alkoxy, halo-C 1 -C 6 alkoxy, C 1 -C 6 alkylthio or C 1 -C 6 alkylsulfonyl;

[0015] Y is selected from halogen, OR 6 , SR 6 , SOR 6 , SO 2 R 6 or NHR 6 ;

[0016] R 6 is selected from hydrogen or C 1 -C 4 alkyl;

[0017] or a salt of a compound of formula I.

[0018] Preferably: in the compound of formula I:

[0019] Q is selected from Q1 or Q2;

[0020] When Q is selected from Q1: R 1 is selected from hydrogen, fluorine, chlorine, bromine or C 1 -C 4 alkyl, R 2Selected from hydrogen or C 1 -C 6 alkyl;

[0021] When Q is selected from Q2: R 1 Selected from C 1 -C 4 alkyl, R 2 Selected from C 1 -C 6 alkyl;

[0022] R 3 Selected from halogen, cyano, nitro, C 1 -C 4 alkyl, halo C 1 -C 3 alkyl, C 1 -C 3 alkoxy, halo C 1 -C 3 alkoxy or C 1 -C 3 alkylsulfonyl;

[0023] n = 0 - 3;

[0024] R 4 、R 5 may be the same or different and are each independently selected from hydrogen, fluorine, chlorine, bromine, nitro, cyano, C 1 -C 4 alkyl, halo C 1 -C 4 alkyl, C 1 -C 4 alkoxy or halo C 1 -C 4 alkoxy;

[0025] Y is selected from Cl, OR 6 or SR 6 ;

[0026] R 6 Selected from C 1 -C 4 alkyl;

[0027] or a salt formed by the compound of formula I with hydrochloric acid, sulfuric acid, phosphoric acid, formic acid, acetic acid, trifluoroacetic acid, oxalic acid, methanesulfonic acid, p-toluenesulfonic acid, benzoic acid, phthalic acid, maleic acid, fumaric acid, sorbic acid, malic acid or citric acid.

[0028] Further preferably: in the compound of formula I:

[0029] Q is selected from Q2;

[0030] R 1 、R 2are each independently selected from methyl;

[0031] R 3 is selected from fluorine, chlorine, bromine, cyano, nitro, methyl, ethyl, isopropyl, tert-butyl, CF 3 , CH 3 O or CF 3 O;

[0032] n = 0 - 3;

[0033] R 4 and R 5 may be the same or different and are each independently selected from hydrogen, fluorine, chlorine, bromine, methyl, ethyl or isopropyl;

[0034] Y is selected from Cl or CH 3 O;

[0035] or a salt formed by the compound of formula I and hydrochloric acid, sulfuric acid, phosphoric acid, formic acid, acetic acid, trifluoroacetic acid, oxalic acid, methanesulfonic acid, p-toluenesulfonic acid, benzoic acid, phthalic acid, maleic acid, fumaric acid, sorbic acid, malic acid or citric acid.

[0036] More preferably, in the compound of formula I:

[0037] Q is selected from Q2;

[0038] R 1 and R 2 are each independently selected from methyl;

[0039] R 3 is selected from fluorine or chlorine;

[0040] n = 0 or 1;

[0041] R 4 and R 5 are each independently selected from hydrogen;

[0042] Y is selected from CH 3 O;

[0043] or a salt formed by the compound of formula I and hydrochloric acid, sulfuric acid, phosphoric acid, formic acid, acetic acid, trifluoroacetic acid, oxalic acid, methanesulfonic acid, p-toluenesulfonic acid, benzoic acid, phthalic acid, maleic acid, fumaric acid, sorbic acid, malic acid or citric acid.

[0044] The fungicide is formulated into an emulsifiable concentrate, aqueous solution, emulsion in water, microemulsion, soluble concentrate, wettable powder, suspension concentrate, oil-based suspension concentrate, granule, water-dispersible granule, emulsifiable powder (or granule), effervescent granule (or tablet), microcapsule suspension or slow-release granule.

[0045] In the emulsifiable concentrate, by weight percentage, the active ingredient is 5 - 80%, the surfactant is 5 - 20%, and the carrier is the balance;

[0046] For the aqueous solution, by weight percentage, the active ingredient is 10 - 50%, the emulsifier is 2 - 15%, other additives are 0 - 20%, and the balance is water;

[0047] For the aqueous emulsion, by weight percentage, the active ingredient is 5 - 40%, the surfactant is 5 - 25%, the solvent is 5 - 20%, and the balance is water;

[0048] For the microemulsion, by weight percentage, the active ingredient is 5 - 30%, the surfactant is 10 - 30%, the solvent is 5 - 25%, and the balance is water;

[0049] For the soluble concentrate, by weight percentage, the active ingredient is 5 - 25%, the surfactant is 8 - 20%, and the balance is the carrier;

[0050] For the suspending agent, by weight percentage, the active ingredient is 5 - 60%, the surfactant is 5 - 20%, and the balance is the water carrier;

[0051] For the oil-based suspending agent, by weight percentage, the active ingredient is 5 - 50%, the surfactant is 5 - 25%, and the balance is the oil-based carrier;

[0052] For the emulsifiable powder (or granule), by weight percentage, the active ingredient is 1 - 30%, the surfactant is 10 - 40%, the organic solvent is 0 - 15%, and the balance is the carrier;

[0053] For the effervescent granule (or tablet), by weight percentage, the active ingredient is 0.5 - 30%, the surfactant is 2 - 15%, and the balance is the carrier;

[0054] For the slow-release granule, by weight percentage, the active ingredient is 0.5 - 10%, the surfactant is 2 - 10%, and the balance is the carrier;

[0055] For the granule, by weight percentage, the active ingredient is 0.1 - 10%, a little water, and the balance is the carrier;

[0056] For the water-dispersible granule, by weight percentage, the active ingredient is 0.5 - 75%, the surfactant is 5 - 20%, and the balance is the inert carrier.

[0057] For the wettable powder, by weight percentage, the active ingredient is 10 - 85%, the dispersant is 3 - 10%, and the balance is the solid inert carrier.

[0058] The composition of the present invention is provided in the form of a finished preparation. Using a triazolinone ether compound (as shown in general formula I) as the active ingredient, the compounds of the present method can be prepared into various preparation types in a manner well-known in the art, including emulsifiable concentrates, aqueous solutions, emulsifiable concentrates, microemulsions, soluble solutions, wettable powders, suspensions, oil-based suspensions, granules, water-dispersible granules, emulsifiable powders (or granules), effervescent granules (or tablets), microcapsule suspensions or sustained-release granules. In any case, the choice of the preparation type depends on the physical, chemical and biological properties of the active ingredient. The content of the active ingredient in the composition is between 1% and 99%, preferably 5 to 80%. The optimal range of the active ingredient content varies depending on the preparation type of the composition.

[0059] The bactericidal preparation of the present invention can be prepared by conventional processing methods. Usually, the composition contains at least one carrier and at least one surfactant. That is, the active substance is mixed with a liquid or solid carrier, and one or several surfactants are added, such as emulsifiers, dispersants, stabilizers, wetting agents. Binders, dyes, sweeteners or defoamers can also be added. In all cases, it should be ensured that the active ingredient of the composition of the present invention is evenly distributed.

[0060] The emulsifiable concentrate is prepared by mixing the technical material of the compound shown in general formula I, an organic solvent and a surfactant to form an oil phase. It usually contains 5 to 50% of the active ingredient, 5 - 20% of the surfactant (the surfactant is, for example, one or several of emulsifiers, stabilizers, penetrants), and the solvent (cosolvent may be contained if necessary), with the balance being the carrier.

[0061] The aqueous solution is prepared by mixing the technical material of the compound shown in general formula I, an inorganic base or an organic base, an organic solvent and a surfactant to form an aqueous phase. It usually contains 10 to 50% of the active ingredient, 2 - 15% of the emulsifier, 0 - 20% of other additives (other additives are, for example, one or several of stabilizers, penetrants), and the balance being water.

[0062] The emulsifiable concentrate is prepared by mixing the technical material of the compound shown in general formula I, an organic solvent and a surfactant to form an oil phase; water and an antifreeze are mixed together to form a homogeneous and transparent aqueous phase. Under high-shear emulsification, the aqueous phase is slowly added to the oil phase or the oil phase is added to the aqueous phase. Usually, the active ingredient is 5 - 40%, the surfactant is 5 - 25% (the surfactant is, for example, one or several of emulsifiers, stabilizers, penetrants), the solvent is 5 - 20%, and the balance is water.

[0063] The microemulsion is prepared by mixing the technical material of the compound shown in general formula I, an organic solvent, a surfactant and water to form a homogeneous and transparent emulsion. Usually, the active ingredient is 5 - 30%, the surfactant is 10 - 30% (the surfactant is, for example, one or several of emulsifiers, stabilizers, penetrants), the solvent is 5 - 25%, and the balance is water.

[0064] The soluble solution is prepared by mixing the technical material of the compound shown in General Formula I, an organic solvent, and a surfactant to form a homogeneous and transparent liquid. Usually, the active ingredient is 5-25%, the surfactant is 8-20% (the surfactant is, for example, one or several of an emulsifier, a stabilizer, and a penetrant), and the balance is the carrier.

[0065] The suspension concentrate is prepared by mixing the technical material of the compound shown in General Formula I, a surfactant, an antifreeze agent, water, etc., and then subjecting it to sand grinding to obtain a stable non-depositing flowable product. Usually, it contains 5-60% of the active ingredient, 5-20% of the surfactant (the surfactant is, for example, one or several of a dispersant, an antifreeze agent, an antifoaming agent, a preservative, a stabilizer, a penetrant, and a thickener), and the balance is the water carrier.

[0066] The dispersible oil suspension concentrate is prepared by subjecting the technical material of the compound shown in General Formula I, a surfactant, and an oil-based carrier to sand grinding in a sand mill until the particle size is qualified. Usually, the active ingredient is 5-50%, the surfactant is 5-25% (the surfactant is, for example, one or several of an emulsifier, a stabilizer, and a penetrant), and the balance is the oil-based carrier.

[0067] The emulsifiable powder (or granule) is prepared by mixing the technical material of the compound shown in General Formula I, an organic solvent, and a surfactant to form a homogeneous and transparent oil phase, and then uniformly spraying it on the pre-crushed carrier. Usually, the active ingredient is 1-30%, the surfactant is 10-40% (the surfactant is, for example, one or several of an emulsifier, a stabilizer, and a penetrant), the organic solvent is 0-15%, and the balance is the carrier.

[0068] The effervescent granule (or tablet) is prepared by mixing and crushing the technical material of the compound shown in General Formula I, a surfactant, and a carrier, and then kneading and granulating (or tableting). Usually, the active ingredient is 0.5-30%, the surfactant is 2-15% (the surfactant is, for example, one or several of a stabilizer, a wetting and dispersing agent, a disintegrant, and a binder), and the balance is the carrier.

[0069] The slow-release granule is prepared by mixing and crushing the technical material of the compound shown in General Formula I, a surfactant, and a carrier, and then coating it with a binder. Usually, the active ingredient is 0.5-10%, the surfactant is 2-10%, and the balance is the carrier.

[0070] The granule is prepared by mixing the technical material of the compound shown in General Formula I and a carrier, kneading, granulating, drying, and coating. Usually, the active ingredient is 0.1-10%, a little water, and the balance is the carrier.

[0071] The water dispersible granule is prepared by mixing the technical material of the compound shown by general formula I, surfactant and carrier, followed by comminution, kneading and granulation. It is usually made into granules with 10 - 100 international standard mesh (1.676 - 0.152 mm), and can be prepared by extrusion, impregnation or spray granulation methods. It usually contains 0.5 - 75% of the active ingredient and 5 - 20% of the surfactant (such as one or several of stabilizer, wetting dispersant, disintegrant and binder), and the balance is the inert carrier.

[0072] The wettable powder is obtained by mixing the technical material of the compound shown by general formula I, surfactant and carrier, followed by comminution. It usually contains 10 - 85% of the active ingredient, 3 - 10% of the dispersant, and the balance is the solid inert carrier.

[0073] The finished formulation of the composition of the present invention can be prepared using carriers (liquid or solid) and various auxiliaries well known to those skilled in the art. For example, it includes but is not limited to the following types of substances.

[0074] The surfactants contained in the bactericidal preparation composition of the present invention include fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, fatty amine polyoxyethylene ether, fatty acid polyoxyethylene ether, acid alcohol ester and its polyoxyethylene ether, fatty amide and its polyoxyethylene ether, alkanolamide and its polyoxyethylene ether, polyoxyethylene-polyoxypropylene block copolymer, sodium alkyl naphthalene sulfonate fatty alcohol polyoxyethylene ether, sorbitan fatty acid ester polyoxyethylene ether, etc. For example: emulsifier SK-50EC, emulsifier SK-51EC, emulsifier 1601, emulsifier 0201B, emulsifier 0203B, emulsifier 500#, emulsifier 600#, emulsifier 700#, emulsifier NP-10, dispersant SK-33L, dispersant SK-33H, emulsifier OX-8686, emulsifier OX-2681, emulsifier 2201, emulsifier OX-690, dispersant DURAMAX TM D-205, dispersant DURAMAX TM D-305, dispersant DURAMAX TM W600, dispersant DURAMAX TMD800, Emulsifier SK-5208T, Emulsifier SK-5215T, Emulsifier YUS-D625, Emulsifier YUS-135B, Emulsifier YUS-EC2200, Emulsifier SK-5026ECH, Emulsifier YUS-110, Emulsifier SK-5212T, Emulsifier YUS-A41B, Emulsifier Emulson AG / 18C, Greenmul 5100, TANEMULSPS29, D865, Emulsifier YUS-2010CX, Emulsifier S-80, Emulsifier T-20, Emulsifier SK-5935, Dispersant YUS-D3020, Dispersant SK-20TX, Dispersant SD811, Wetting Agent SP-3266E, Dispersant SP-2728, Dispersant SP-SC29, Dispersant SP-28F, Dispersant SP-2750, Dispersant TENSIOFIX SC, TENSIOFIX 96DB10, Wetting Agent TENSIOFIX BCZ, Dispersant D425, Dispersant YUS-FS1, Dispersant YUS-FS3000, Dispersant YUS-FS3300, Dispersant YUS-FS7PG, Dispersant YUS-TXC, Dispersant SP-27001, Greensperse BE02, Greensperse BE23, TANEMUL DA2883, TANEMUL DA2880, TANEMUL DA260, Atlox 4913, XN-45S, Emulsifier 507, Dispersant SK-33SC, Dispersant SK-541, Dispersant SK-551, Dispersant SK-94S7, Dispersant SK-551G, Emulsifier SK-5218CP, Emulsifier SK-5220T, Dispersant SK-92FS1, Emulsifier YUS-CP120, Triphenylvinylphenol Polyoxyethylene(n 20)Triethanolamine salt of ether phosphoric acid, synergist SK-41G, synergist SK-41CN, synergist SK-41A, ULTRASURF OD21, ULTRASURF OD23, emulsifier YUS-OD1200, emulsifier AEO-3, dispersant SP-OF3468, dispersant SP-OF3472, G-VO / 02N, Greenmul EF68, Greenmul EF46, Atlox 4912, Atlox 4914, GR7M, emulsifier OX-635, emulsifier OX-622, emulsifier OX-653, emulsifier OX-667, emulsifier AEO-9, emulsifier T-85, dispersant YUS-5050PB, dispersant YUS-EP70G, dispersant YUS-WG5, SP-4302 (humidity synergist), dispersant VE / 10, dispersant OE / 02, dispersant OE / 03, dispersant OE / 08, dispersant OE / 09, dispersant OE150, dispersant Emulson CO40, dispersant Emulson AG / 1100, ULTRASURFO / 23, sodium salt of alkylnaphthalene sulfonic acid condensate, sodium methylnaphthalene sulfonate formaldehyde condensate, polycarboxylate dispersant GY-D800, polycarboxylate dispersant GY-D04, polycarboxylate dispersant GY-D02, sodium salt of naphthalene sulfonic acid formaldehyde condensate, sodium salt of naphthol sulfonic acid formaldehyde condensate, sodium methylene naphthalene sulfonate, sodium N-methylaminoethyl oleate sulfonate, dispersant SP-SC3, Darun dispersant D909S, alkylnaphthalene sulfonate formaldehyde condensate (NNO), dispersant YUS-NV1420, dispersant YUS-WG4, dispersant YUS-WP1, dispersant YUS-CH7000, emulsifier PICO-LOE, dispersant PICO-CS300M, dispersant PICO-SF3, dispersant PICO-SWP1, dispersant PICO-SF1, dispersant Geropon Ultrasperse, dispersant GeroponExtra, dispersant Soprophor SC, dispersant Geropon DA1349, dispersant TENSIOFIX LX SPECIAL, dispersant TENSIOFIX DB08, dispersant Tensiofix AMS303, dispersant Tensiofix XA265, dispersant Tensiofix EW70, dispersant Tensiofix96DB10, dispersant SK-24R, dispersant SK-25CH, dispersant SK-34SC, dispersant YUS-CH1100, dispersant Supragil MNS / 90, dispersant Soprophor FD, dispersant Soprophor TSP / 461, dispersant Soprophor796 / P, dispersant SD819, dispersant MorwetD-400, Dispersant Morwet D-360, Dispersant Morwet D-390, Dispersant Geronol ODessa 01, Dispersant Geronol ODessa 05, Dispersant YUS-D935, Dispersant TANEMULDA266, Dispersant TANEMUL AG281, Octylphenol Polyoxyethylene Ether Sulfate, Wetting Agent Morwet EFW, Wetting Agent Igepal BC / 10, Wetting Agent GEROPONL-WET / P, Wetting Agent Supragil WP, Wetting Agent Supragil GN, Wetting Agent Rhodasurf 860 / p, Emulsifier YUS-A51G, Wetting Agent YUS-LXC, Wetting Agent YUS-SXC, Sodium Isopropylnaphthalenesulfonate, Alcohol Polyoxyethylene Ether Sulfate, Alkylphenol Polyoxyethylene Ether Formaldehyde Condensate Sulfate, Alkyl Sulfosuccinate, Sodium Lauryl Alcohol Polyoxyethylene Ether Sulfonate, Sodium Dodecylbenzenesulfonate, Sodium Dodecyl Sulfate, Calcium Dodecylbenzenesulfonate, Calcium Lignosulfonate, Alkylamidotaurate, and so on.

[0075] The carrier contained in the bactericidal preparation composition of the present invention can be solid or liquid, and any carrier commonly used for formulating bactericidal compositions can be used.

[0076] If water is used as a solvent or diluent, organic solvents can also be used as auxiliary solvents or antifreeze additives. Suitable organic solvents include aromatic hydrocarbons, chlorinated aromatic hydrocarbons, aliphatic hydrocarbons, chlorinated aliphatic hydrocarbons, etc. Particularly suitable are polar solvents such as alcohols and their ethers and esters, ketones, etc., as well as vegetable oils and methyl cellulose. Mixtures of different liquids are often applicable. For example, methanol, ethanol, isopropanol, butanol, ethylene glycol, ethylene glycol methyl ether, propylene glycol, glycerol, sorbitol, benzyl alcohol, furfuryl alcohol, cyclohexanol, acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone, N-methyl-pyrrolidone, N,N-dimethyl decanamide, N,N-dimethylacetamide, triethyl phosphate, tributyl phosphate, methyl oleate, dimethylformamide, dimethyl sulfoxide, methylated soybean oil, Armid DM10, Armid FMPC, Rhodiasolv Green SV-92, Rhodiasolv Green SV-33, Rhodiasolv Green 25, solvent naphtha S-150, solvent naphtha S-200, light mineral oil, paraffin wax, and kerosene, etc. Mixtures of different liquids are often applicable.

[0077] Suitable solid carriers include natural or synthetic ones, such as: clay, diatomaceous earth, bentonite, kaolin, attapulgite, magnesium aluminum silicate, activated clay, silica white, light calcium carbonate, pottery clay, ammonium sulfate, montmorillonite, etc.

[0078] Suitable defoamers are Antifoam A, defoamer SAG1522, WJX-1, silicone-based, C 8～10 fatty alcohols, phosphate esters, C 10～20 saturated fatty acids (such as capric acid) and amides, etc.

[0079] Suitable preservatives are Kathon, EQ, sodium benzoate, etc.

[0080] Suitable thickeners can be synthetic (such as carboxymethyl alcohol, polyvinyl alcohol, polyvinyl acetate) or natural water-soluble polymers (such as xanthan gum, gelatin, gum arabic, polyvinylpyrrolidone, magnesium aluminum silicate, TENSIOFIX 869, polyvinyl alcohol, polyethylene glycol, phenolic resin, shellac, methyl cellulose, soluble starch, sodium carboxymethyl starch, carboxymethyl cellulose, and sodium alginate, etc.), and are added to the preparation in the form of powder, granule or latex.

[0081] Suitable binders can be synthetic (such as polyvinyl alcohol, polyvinyl acetate) or natural water-soluble polymers (such as xanthan gum, gelatin, gum arabic, polyvinylpyrrolidone, magnesium aluminum silicate, polyvinyl alcohol, polyethylene glycol, phenolic resin, shellac, methyl cellulose, soluble starch, dispersant TANEMUL AG281, carboxymethyl cellulose, and sodium alginate, etc.), and are added to the preparation in the form of powder, granule or latex.

[0082] Effervescent disintegrants: The acidic components are organic acids and inorganic acids, such as: tartaric acid, citric acid, salicylic acid, phosphoric acid, etc.; the basic components are basic carbonates and carbonates, such as: sodium bicarbonate, sodium carbonate, potassium bicarbonate, potassium carbonate, and ammonium bicarbonate, etc.

[0083] Warning colors are: inorganic pigments iron oxide, titanium oxide or Prussian blue; organic dyes such as alizarin, acid scarlet G, basic rose red, azo dyes, metal phthalocyanine or triphenylmethane dyes; flavoring agents can also be contained, such as natural aromatic oils.

[0084] Wall materials are: natural polymer materials, such as: gelatin, gum arabic, agar, alginate, chitosan, fibrin, zein, etc.; semi-synthetic polymer materials, such as: methyl (ethyl) cellulose, carboxymethyl cellulose (sodium), cellulose acetate and its esters, and partial glycerides, etc.; fully synthetic polymer materials, such as: polyacrylate resin, polylactic acid, melamine resin, urea-formaldehyde resin, polyamide, polyester, polymethyl methacrylate, polyurea, polyurethane, etc.

[0085] An application of the described fungicide, the fungicide is used to control diseases such as wheat powdery mildew, cucumber powdery mildew, wheat rust, etc.

[0086] The described bactericidal preparation is applied at 10 - 1000 grams of active ingredient per hectare to the diseases to be controlled and the medium on which they grow.

[0087] The bactericidal preparation composition of the present invention can be diluted or directly added with water for spraying by the user before use, or it can be used directly.

[0088] The technical scheme of the present invention also includes the use of the fungicide preparation: the fungicide composition of the present invention is used for wheat, cucumber, soybean and rice crops, and is used to prevent and control wheat powdery mildew, wheat rust, wheat head blight, cucumber powdery mildew, soybean rust, rice blast and late blight and other diseases, and is safe for crops.

[0089] The advantages of the present invention are:

[0090] Based on the particularity of the biological activity of the pesticide itself and guided by theoretical knowledge, the present invention studies the active component structure, active groups, and mode of action, and selects an adjuvant system suitable for the effective component, thereby achieving the purpose of controlling the dynamic surface tension of the spray liquid and the size of the droplet particle size, making the liquid drift small, evaporate slowly, spread, wet, and adhere well on the target, and have a long residence time, thereby improving the utilization rate of the pesticide and solving the problem of poor efficacy of the agent prepared by the usual processing method. The adjuvant system of the present invention has the advantages that, on the one hand, the adjuvant can well anchor the active component, so that the particles of the active component are prevented from aggregating due to the steric hindrance and electrostatic repulsion, thereby obtaining good physical stability of the preparation system, and can assist the active component to be quickly, evenly and stably dispersed in the spray carrier. The particle size of the active component is small and the distribution is narrow, and the surface tension of the liquid medicine is appropriate, thereby ensuring the distribution and attachment of the pesticide liquid medicine on the surface of the organism (the leaf surface of the plant), promoting the absorption of the agent by the organism, and even increasing the conduction of the agent in the organism, so as to achieve the purpose of increasing the retention amount of the pesticide on the plant surface, prolonging the retention time and improving the penetration ability of the plant epidermis. On the other hand, the spreading ability is improved, so that the liquid medicine directly enters the plant body from the stomata of the plant and is absorbed, thereby fully improving the efficacy of the active ingredient of the fungicide obtained by the present invention, not only improving the prevention effect of the effective ingredient of the pesticide and enhancing its safety to crops, but also reducing the dosage and cost, and hitting the target to the maximum extent with the minimum dosage, and improving the compatibility with the environment, reducing the harm of the pesticide to the human body and the pollution to the environment. The fungicide composition of the present invention has broad market prospects, as well as good economic, social and ecological benefits. Specific implementation method

[0091] The following specific examples are used to further illustrate the present invention, but the present invention is by no means limited to these examples. Methods well known to those skilled in the art should be included within the scope of the present invention.

[0092] In the formulation ratios of all preparations, percentages and parts are by weight. The preparation of the active ingredient (as shown in General Formula I) can be obtained with reference to the relevant records in (CN 102336744 B).

[0093] Among them, the active ingredient is the compound shown in General Formula I, and the specific compounds shown in General Formula I are: Compound A1 (Q is selected from Q2; R 1 , R 2 are both selected from methyl; n = 0; R 4 , R 5 are both selected from hydrogen; Y is selected from CH 3 O). A2 (Q is selected from Q2; R 1 , R 2 are both selected from methyl; R 3 is selected from fluorine; n = 1; R 4 , R 5 are both selected from hydrogen; Y is selected from CH 3 O). A3 (Q is selected from Q2; R 1 , R 2 are both selected from methyl; R 3 is selected from chlorine; n = 1; R 4 , R 5 are both selected from hydrogen; Y is selected from CH 3 O). All other raw materials are commercially available products.

[0094] Formulation Examples of Preparations

[0095] Example 1. Preparation of 5% Compound A1 Emulsifiable Concentrate

[0096] According to the formulation requirements, add 5 parts of Compound A1, 5 parts of emulsifier SK-50EC, 5 parts of emulsifier SK-51EC, 1 part of emulsifier 500, 1 part of emulsifier 700, 5 parts of methanol, 30 parts of Rhodiasolv Green 25, and solvent oil 150 to make up to 100% into a mixing kettle, stir and mix evenly, and heat and dissolve with a hot water bath if necessary to obtain 5% Compound A1 emulsifiable concentrate. The results of the determination of physical and chemical properties: emulsion stability (standard hard water, 200 times), qualified; low temperature stability, qualified; thermal storage stability, qualified, decomposition rate after thermal storage (54 ± 2 °C / 14 d) 0.5%. At normal temperature: surface tension (dyn / cm), 35.81 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 30.3. After thermal storage (54 ± 2 °C / 14 d): surface tension (dyn / cm), 36.5 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 29.9.

[0097] A1 can also be replaced with the triazolinone ether compound (as shown in General Formula I) A2 or A3 described in this specification to form new examples.

[0098] Example 2, Preparation of 10% Compound A1 EC

[0099] According to the formulation requirements, 10 parts of Compound A1, 2 parts of Emulsifier 500, 5 parts of Emulsifier 0201B, 5 parts of Emulsifier YUS135, 5 parts of methanol, 30 parts of Armid FMPC, and Solvent Oil 150 were added to the mixing kettle to make up 100%, and stirred and mixed evenly. When necessary, it was heated and dissolved in a hot water bath to obtain 10% Compound A1 EC. The determination results of physical properties: emulsion stability (standard hard water, 200 times), qualified; low temperature stability, qualified; heat storage stability, qualified, decomposition rate after heat storage (54 ± 2°C / 14d) 0.8%. At room temperature: surface tension (dyn / cm), 35.28 (diluted 800-fold solution); retained liquid medicine amount (mg / cm 2 ), 29.1. After heat storage (54 ± 2°C / 14d): surface tension (dyn / cm), 35.98 (diluted 800-fold solution); retained liquid medicine amount (mg / cm 2 ), 28.7.

[0100] A1 can also be replaced with the triazolinone ether compound (as shown in general formula I) A2 or A3 described in this specification to form a new example.

[0101] Example 3, Preparation of 5% Compound A1 EC

[0102] According to the formulation requirements, 5 parts of Compound A1, 1 part of Emulsifier 700, 6 parts of YUSD625, 4 parts of OX-8686, 5 parts of methanol, 25 parts of Rhodiasolv Green 25, and Solvent Oil 150 were added to the mixing kettle to make up 100%, and stirred and mixed evenly. When necessary, it was heated and dissolved in a hot water bath to obtain 5% Compound A1 EC. The determination results of physical properties: emulsion stability (standard hard water, 200 times), qualified; low temperature stability, qualified; heat storage stability, qualified, decomposition rate after heat storage (54 ± 2°C / 14d) 1.1%. At room temperature: surface tension (dyn / cm), 36.02 (diluted 800-fold solution); retained liquid medicine amount (mg / cm 2 ), 31.1. After heat storage (54 ± 2°C / 14d): surface tension (dyn / cm), 35.92 (diluted 800-fold solution); retained liquid medicine amount (mg / cm 2 ), 30.5.

[0103] A1 can also be replaced with one of the triazolinone ether compounds (as shown in general formula I) A2 or A3 described in this specification to form a new example.

[0104] Example 4, Preparation of 5% Compound A1 EC

[0105] According to the formulation requirements, add 5 parts of compound A1, 6 parts of emulsifier SK-50EC, 6 parts of emulsifier SK-51EC, 3 parts of emulsifier 0201B, 5 parts of methanol, 20 parts of Armid DM10, and make up to 100% with solvent oil 200 into the mixing kettle, stir and mix evenly, and heat and dissolve with a hot water bath if necessary to obtain 5% compound A1 emulsifiable concentrate. The determination results of physical properties: emulsion stability (standard hard water, 200 times), qualified; low temperature stability, qualified; heat storage stability, qualified, decomposition rate after heat storage (54±2°C / 14d) 0.6%. At room temperature: surface tension (dyn / cm), 36.21 (diluted 800-fold solution); retained liquid medicine amount (mg / cm 2 ), 27.2. After heat storage (54±2°C / 14d): surface tension (dyn / cm), 36.31 (diluted 800-fold solution); retained liquid medicine amount (mg / cm 2 ), 26.8.

[0106] A1 can also be replaced with triazolinone ether compounds (as shown in general formula I) A2 or A3 described in this specification to form new examples.

[0107] Example 5, Preparation of 15% compound A2 emulsifiable concentrate

[0108] According to the formulation requirements, add 15 parts of compound A2, 5 parts of YUS135B, 4 parts of YUSD625, 2 parts of emulsifier 500, 5 parts of methanol, 30 parts of Rhodiasolv Green 25, and make up to 100% with solvent oil 150 into the mixing kettle, stir and mix evenly, and heat and dissolve with a hot water bath if necessary to obtain 15% compound A2 emulsifiable concentrate. The determination results of physical properties: emulsion stability (standard hard water, 200 times), qualified; low temperature stability, qualified; heat storage stability, qualified, decomposition rate after heat storage (54±2°C / 14d) 0.7%. At room temperature: surface tension (dyn / cm), 35.33 (diluted 800-fold solution); retained liquid medicine amount (mg / cm 2 ), 28.3. After heat storage (54±2°C / 14d): surface tension (dyn / cm), 35.89 (diluted 800-fold solution); retained liquid medicine amount (mg / cm 2 ), 27.6.

[0109] A2 can also be replaced with triazolinone ether compounds (as shown in general formula I) A1 or A3 described in this specification to form new examples.

[0110] Example 6, Preparation of 10% compound A1 dispersible oil suspension

[0111] According to the formulation requirements, 10 parts of compound A1, 5 parts of ULTRASURF OD21, 8 parts of emulsifier YUS-135B, 3 parts of emulsifier 0201B, and 1 part of dispersant DURAMAX TM W600, 3 parts of G-VO / 02N, 1 part of silica white, and methyl oleate are added to the mixing tank in sequence to make up to 100% and mixed. First, it is coarsely crushed and homogenized by high shear, then pumped into a sand mill for fine grinding. The particle size of the sand-milled material is detected by a particle size distribution analyzer. After the particle size meets the standard requirements, it is filtered to obtain a 10% dispersible oil suspension concentrate of compound A1. The determination results of physical properties: dispersibility, good; decomposition rate after heat storage (54±2°C / 14d), 0.7%. At room temperature: surface tension (dyn / cm), 34.2 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 30.2; particle size (D50 / 97, μm), 0.58 / 1.63; suspension rate, 100%. After heat storage (54±2°C / 14d): surface tension (dyn / cm), 34.9 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 29.3, particle size (D50 / 97, μm), 0.66 / 1.68; suspension rate, 100%.

[0112] A1 can also be replaced with triazolinone ether compounds (such as those shown in general formula I) A2 or A3 described in this specification to form new examples.

[0113] Example 7. Preparation of 20% dispersible oil suspension concentrate of compound A1

[0114] According to the formulation requirements, 20 parts of compound A1, 12 parts of Greenmul EF46, 6 parts of TENSIOFIX 96DB10, and 2 parts of dispersant DURAMAX TM W600, 1 part of TENSIOFIX 869, and methylated soybean oil are added to the mixing tank in sequence to make up to 100% and mixed. First, it is coarsely crushed and homogenized by high shear, then pumped into a sand mill for fine grinding. The particle size of the sand-milled material is detected by a particle size distribution analyzer. After the particle size meets the standard requirements, it is filtered to obtain a 20% dispersible oil suspension concentrate of compound A1. The determination results of physical properties: dispersibility, good; decomposition rate after heat storage (54±2°C / 14d), 1.1%. At room temperature: surface tension (dyn / cm), 32.12 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 28.8; particle size (D50 / 97, μm), 0.71 / 1.75; suspension rate, 100%. After heat storage (54±2°C / 14d): surface tension (dyn / cm), 32.93 (diluted 800-fold solution); retained liquid amount (mg / cm 2), 28.1, particle size (D50 / 97, μm), 0.75 / 1.82; suspension rate, 100%.

[0115] A1 can also be replaced with the triazolinone ether compounds (such as those shown in general formula I) A2 or A3 described in this specification to form new examples.

[0116] Example 8. Preparation of 5% Compound A1 Dispersible Oil Suspension

[0117] According to the formulation requirements, 5 parts of Compound A1, 6 parts of dispersant SP-OF3472, 6 parts of dispersant SP-OF3468, 3 parts of emulsifier YUS-135B, 1 part of silica white, and methyl oleate were added to the mixing tank in sequence to make up to 100% and mixed. First, it was coarsely pulverized and homogenized by high shear, and then pumped into a sand mill for fine grinding. The particle size of the sand-milled material was detected with a particle size distribution analyzer. After the particle size reached the standard requirements, it was filtered to obtain 5% Compound A1 dispersible oil suspension. The determination results of physical properties: dispersibility, good; decomposition rate after heat storage (54 ± 2°C / 14d) 1.2%. At room temperature: surface tension (dyn / cm), 35.32 (diluted 800-fold solution); retained liquid amount of the medicament (mg / cm 2 ), 29.3; particle size (D50 / 97, μm), 0.67 / 1.82; suspension rate, 100%. After heat storage (54 ± 2°C / 14d): surface tension (dyn / cm), 34.96 (diluted 800-fold solution); retained liquid amount of the medicament (mg / cm 2 ), 28.8, particle size (D50 / 97, μm), 0.70 / 1.86; suspension rate, 100%.

[0118] A1 can also be replaced with the triazolinone ether compounds (such as those shown in general formula I) A2 or A3 described in this specification to form new examples.

[0119] Example 9. Preparation of 10% Compound A1 Dispersible Oil Suspension

[0120] According to the formulation requirements, 10 parts of compound A1, 6 parts of TENSIOFIX 96DB10, 6 parts of emulsifier YUS-135B, 2 parts of emulsifier 500, 1 part of TENSIOFIX 869, and methyl oleate are added to the mixing tank in sequence to make up 100%, and they are mixed. First, they are roughly crushed and homogenized by high shear, and then pumped into a sand mill for fine grinding. The particle size of the sand-milled material is detected by a particle size distribution analyzer. After the particle size meets the standard requirements, filtration is carried out to obtain a 10% dispersible oil suspension concentrate of compound A1. The determination results of physical properties: dispersibility, good; decomposition rate after heat storage (54±2°C / 14d) is 0.9%. At room temperature: surface tension (dyn / cm), 33.56 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 30.1; particle size (D50 / 97, μm), 0.73 / 1.91; suspension rate, 100%. After heat storage (54±2°C / 14d): surface tension (dyn / cm), 33.02 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 29.6, particle size (D50 / 97, μm), 0.78 / 2.01; suspension rate, 100%.

[0121] A1 can also be replaced with triazolinone ether compounds (such as those shown in general formula I) A2 or A3 described in this specification to form new examples.

[0122] Example 10. Preparation of 30% dispersible oil suspension concentrate of compound A3

[0123] According to the formulation requirements, 30 parts of compound A3, 5 parts of emulsifier YUS-OD1200, 4 parts of Atlox 4912, 1 part of emulsifier 500, 6 parts of dispersant SK-94S7, and methylated soybean oil are added to the mixing tank in sequence to make up 100%, and they are mixed. First, they are roughly crushed and homogenized by high shear, and then pumped into a sand mill for fine grinding. The particle size of the sand-milled material is detected by a particle size distribution analyzer. After the particle size meets the standard requirements, filtration is carried out to obtain a 30% dispersible oil suspension concentrate of compound A3. The determination results of physical properties: dispersibility, good; decomposition rate after heat storage (54±2°C / 14d) is 1.1%. At room temperature: surface tension (dyn / cm), 33.52 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 29.5; particle size (D50 / 97, μm), 0.69 / 1.98; suspension rate, 100%. After heat storage (54±2°C / 14d): surface tension (dyn / cm), 34.15 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 28.5, particle size (D50 / 97, μm), 0.76 / 2.03; suspension rate, 100%.

[0124] A3 can also be replaced with the triazolinone ether compounds (such as those shown in general formula I) A1 or A2 described in this specification to form new examples.

[0125] Example 11. Preparation of 10% Compound A1 Suspension

[0126] According to the formulation requirements, 10 parts of Compound A1, 2 parts of dispersant SK-20TX, 5 parts of dispersant SD811, 4 parts of dispersant SK-25CH, 1 part of silica white, 1 part of magnesium aluminum silicate, 0.15 part of xanthan gum, 0.2 part of preservative EQ, 0.6 part of defoamer SAG1522, 5 parts of ethylene glycol, and water are added to the mixing tank in sequence to make up to 100% and mixed. First, it is coarsely pulverized and homogenized by high shear, and then pumped into a sand mill for fine grinding. The particle size of the sand-milled material is detected with a particle size distribution analyzer. After the particle size meets the standard requirements, it is filtered to obtain 10% Compound A1 suspension. The determination results of physical property indicators: dispersibility, good; decomposition rate after heat storage (54 ± 2°C / 14d) is 1.2%. At room temperature: surface tension (dyn / cm), 35.31 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 28.8; particle size (D50 / 97, μm), 0.69 / 1.89; suspension rate, 100%. After heat storage (54 ± 2°C / 14d): surface tension (dyn / cm), 36.1 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 27.9, particle size (D50 / 97, μm), 0.72 / 1.98; suspension rate, 100%.

[0127] A1 can also be replaced with the triazolinone ether compounds (such as those shown in general formula I) A2 or A3 described in this specification to form new examples.

[0128] Example 12. Preparation of 10% Compound A1 Suspension

[0129] According to the formulation requirements, 10 parts of compound A1, 5 parts of dispersant SP-SC3, 5 parts of dispersant SD811, 3 parts of Atlox4913, 0.8 part of silica white, 0.8 part of magnesium aluminum silicate, 0.12 part of xanthan gum, 0.2 part of preservative EQ, 0.6 part of defoamer SAG1522, 5 parts of ethylene glycol, and water are added up to 100% and successively added to the mixing tank for mixing. First, it is coarsely pulverized and homogenized by high shear, and then pumped into a sand mill for fine grinding. The particle size of the sand-milled material is detected by a particle size distribution analyzer. After the particle size meets the standard requirements, it is filtered to obtain a 10% compound A1 suspending agent. The determination results of physical properties: dispersibility, good; decomposition rate after heat storage (54 ± 2 °C / 14d) is 0.9%. At room temperature: surface tension (dyn / cm), 33.89 (800-fold diluted solution); retained liquid amount (mg / cm 2 ), 30.1; particle size (D50 / 97, μm), 0.75 / 1.99; suspension rate, 100%. After heat storage (54 ± 2 °C / 14d): surface tension (dyn / cm), 34.66 (800-fold diluted solution); retained liquid amount (mg / cm 2 ), 29.6, particle size (D50 / 97, μm), 0.76 / 2.03; suspension rate, 100%.

[0130] A1 can also be replaced with triazolinone ether compounds (as shown in general formula I) A2 or A3 described in this specification to form new examples.

[0131] Example 13. Preparation of 30% compound A1 suspending agent

[0132] According to the formulation requirements, 30 parts of compound A1, 3 parts of dispersant SK-20TX, 4 parts of emulsifier 0201B, 3 parts of wetting agent SP3266E, 3 parts of dispersant YUS-FS3000, 0.5 part of silica white, 0.5 part of magnesium aluminum silicate, 0.1 part of xanthan gum, 0.2 part of preservative Kathon, 0.6 part of defoamer SAG1522, 5 parts of 1,2-propanediol, and water are added up to 100% and successively added to the mixing tank for mixing. First, it is coarsely pulverized and homogenized by high shear, and then pumped into a sand mill for fine grinding. The particle size of the sand-milled material is detected by a particle size distribution analyzer. After the particle size meets the standard requirements, it is filtered to obtain a 30% compound A1 suspending agent. The determination results of physical properties: dispersibility, good; decomposition rate after heat storage (54 ± 2 °C / 14d) is 1.3%. At room temperature: surface tension (dyn / cm), 34.28 (800-fold diluted solution); retained liquid amount (mg / cm 2), 29.3; particle size (D50 / 97, μm), 0.65 / 1.92; suspension rate, 100%. After heat storage (54 ± 2 °C / 14 d): surface tension (dyn / cm), 33.09 (800-fold diluted solution); retained liquid medicine amount (mg / cm 2 ), 28.8, particle size (D50 / 97, μm), 0.71 / 2.05; suspension rate, 100%.

[0133] A1 can also be replaced with the triazolinone ether compounds (as shown in general formula I) A2 or A3 described in this specification to form new examples.

[0134] Example 14. Preparation of 5% soluble concentrate of compound A1

[0135] According to the formulation requirements, 5 parts of compound A1, 5 parts of emulsifier SK-5208T, 3 parts of emulsifier 0201B, 6 parts of emulsifier YUS-135B, 2 parts of emulsifier 500, 3 parts of dispersant SK-541, 25 parts of Rhodiasolv Green 25, and triethyl phosphate are made up to 100% and mixed evenly. When necessary, heat and dissolve with a hot water bath to obtain a 5% soluble concentrate of compound A1. The determination results of physical properties: good dilution stability, decomposition rate 1.3% after heat storage (54 ± 2 °C / 14 d). At room temperature: surface tension (dyn / cm), 33.09 (800-fold diluted solution); retained liquid medicine amount (mg / cm 2 ), 31.1. After heat storage (54 ± 2 °C / 14 d): surface tension (dyn / cm), 35.09 (800-fold diluted solution); retained liquid medicine amount (mg / cm 2 ), 28.8.

[0136] A1 can also be replaced with the triazolinone ether compounds (as shown in general formula I) A2 or A3 described in this specification to form new examples.

[0137] Example 15. Preparation of 10% soluble concentrate of compound A1

[0138] According to the formulation requirements, 10 parts of compound A1, 5 parts of dispersant YUS-D3020, 5 parts of emulsifier 0201B, 3 parts of emulsifier T-20, 2 parts of emulsifier 500, 3 parts of dispersant SK-551, 30 parts of N,N-dimethyldecanamide, and triethyl phosphate are made up to 100% and mixed evenly. When necessary, heat and dissolve with a hot water bath to obtain a 10% soluble concentrate of compound A1. The determination results of physical properties: good dilution stability, decomposition rate 1.2% after heat storage (54 ± 2 °C / 14 d). At room temperature: surface tension (dyn / cm), 34.52 (800-fold diluted solution); retained liquid medicine amount (mg / cm 2), 29.9. After heat storage (54 ± 2 °C / 14 d): Surface tension (dyn / cm), 34.85 (800-fold diluted solution); Amount of retained liquid medicine (mg / cm 2 ), 28.2.

[0139] A1 can also be replaced with the triazolinone ether compound (as shown in general formula I) A2 or A3 described in this specification to form new examples.

[0140] Example 16, Preparation of 10% Compound A1 Soluble Concentrate

[0141] According to the formulation requirements, 10 parts of Compound A1, 6 parts of emulsifier SK-5208T, 5 parts of emulsifier 0201B, 3 parts of dispersant DURAMAXTM W600, 5 parts of emulsifier 500, 20 parts of Armid FMPC, and triethyl phosphate are made up to 100% and mixed evenly. When necessary, it is heated and dissolved in a hot water bath to obtain 10% Compound A1 soluble concentrate. The determination results of physical properties: Good dilution stability, decomposition rate after heat storage (54 ± 2 °C / 14 d) is 1.1%. At room temperature: Surface tension (dyn / cm), 36.1 (800-fold diluted solution); Amount of retained liquid medicine (mg / cm 2 ), 28.6. After heat storage (54 ± 2 °C / 14 d): Surface tension (dyn / cm), 35.83 (800-fold diluted solution); Amount of retained liquid medicine (mg / cm 2 ), 28.1.

[0142] A1 can also be replaced with the triazolinone ether compound (as shown in general formula I) A2 or A3 described in this specification to form new examples.

[0143] Example 17, Preparation of 10% Compound A1 Soluble Concentrate

[0144] According to the formulation requirements, 10 parts of Compound A1, 5 parts of dispersant YUS-D3020, 5 parts of emulsifier SK-5208T, 5 parts of emulsifier YUS-135B, 3 parts of dispersant SK-551, 20 parts of Armid DM10, and triethyl phosphate are made up to 100% and mixed evenly. When necessary, it is heated and dissolved in a hot water bath to obtain 10% Compound A1 soluble concentrate. The determination results of physical properties: Good dilution stability, decomposition rate after heat storage (54 ± 2 °C / 14 d) is 1.2%. At room temperature: Surface tension (dyn / cm), 33.98 (800-fold diluted solution); Amount of retained liquid medicine (mg / cm 2 ), 27.9. After heat storage (54 ± 2 °C / 14 d): Surface tension (dyn / cm), 34.2 (800-fold diluted solution); Amount of retained liquid medicine (mg / cm 2 ), 26.8.

[0145] A1 can also be replaced with the triazolinone ether compounds (such as those shown in general formula I) A2 or A3 described in this specification to form new embodiments.

[0146] Example 18. Preparation of 15% soluble concentrate of compound A2

[0147] According to the formulation requirements, 15 parts of compound A2, 3 parts of emulsifier T-20, 8 parts of emulsifier 0201B, 6 parts of emulsifier YUS-135B, 5 parts of emulsifier 500, 3 parts of dispersant DURAMAXTM W600, 20 parts of Rhodiasolv Green25 are mixed evenly, and when necessary, heated and dissolved in a hot water bath to obtain 15% soluble concentrate of compound A2. The results of physical property index determination: good dilution stability, decomposition rate of 1.1% after heat storage (54 ± 2°C / 14d). At room temperature: surface tension (dyn / cm), 34.59 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 30.1. After heat storage (54 ± 2°C / 14d): surface tension (dyn / cm), 36.71 (diluted 800-fold solution); retained liquid amount (mg / cm 2 ), 29.3.

[0148] A2 can also be replaced with the triazolinone ether compounds (such as those shown in general formula I) A1 or A3 described in this specification to form new embodiments.

[0149] Example 19. Preparation of 15% emulsion in water of compound A2

[0150] According to the formulation requirements, 15 parts of compound A2, 7 parts of emulsifier 2201, 4 parts of emulsifier SK-5935, 4 parts of emulsifier 0201B, 10 parts of tributyl phosphate, 8 parts of dimethyl sulfoxide, 25 parts of Rhodiasolv Green 25 are added to the mixing kettle, stirred and mixed to dissolve into a homogeneous oil phase. Under high-speed stirring, the remaining water (made up to 100%) is added to the oil phase to obtain 15% emulsion in water of compound A2 with good dispersibility.

[0151] A2 can also be replaced with the triazolinone ether compounds (such as those shown in general formula I) A1 or A3 described in this specification to form new embodiments.

[0152] Example 20. Preparation of 10% emulsion in water of compound A3

[0153] According to the formulation requirements, add 10 parts of compound A3, 6 parts of emulsifier SK-5212T, 4 parts of emulsifier YUS-A51G, 5 parts of emulsifier 0201B, 10 parts of tributyl phosphate, and 25 parts of Armid FMPC into the mixing kettle respectively, stir and mix to dissolve into a uniform oil phase. Under high-speed stirring, add the remaining water (to make up to 100%) to the oil phase, and a 10% aqueous emulsion of compound A3 with good dispersibility can be obtained.

[0154] Compound A3 can also be replaced with triazolinone ether compounds (such as those shown in general formula I) A1 or A2 described in this specification to form new examples.

[0155] Example 21, Preparation of 10% Compound A1 Microemulsion

[0156] According to the formulation requirements, add 10 parts of compound A1, 6 parts of emulsifier YUS-A41B, 2 parts of emulsifier 1601#, 6 parts of emulsifier OX-8686, 5 parts of emulsifier 0201B, 10 parts of Rhodiasolv Green SV-33, and 5 parts of cyclohexanone together to dissolve into a uniform oil phase. Make up the remaining amount with water to 100%. Under high-speed stirring, add the aqueous phase to the oil phase or add the oil phase to the aqueous phase to form a 10% compound A1 microemulsion with good dispersibility.

[0157] Compound A1 can also be replaced with triazolinone ether compounds (such as those shown in general formula I) A2 or A3 described in this specification to form new examples.

[0158] Example 22, Preparation of 5% Compound A2 Microemulsion

[0159] According to the formulation requirements, add 5 parts of compound A2, 5 parts of emulsifier YUS-A51G, 2 parts of emulsifier OX-690, 8 parts of emulsifier SK-5208T, 5 parts of emulsifier 0201B, 5 parts of Rhodiasolv Green SV-92, and 5 parts of Armid FMPC together to dissolve into a uniform oil phase. Make up the remaining amount with water to 100%. Under high-speed stirring, add the aqueous phase to the oil phase or add the oil phase to the aqueous phase to form a 5% compound A2 microemulsion with good dispersibility.

[0160] Compound A2 can also be replaced with triazolinone ether compounds (such as those shown in general formula I) A1 or A3 described in this specification to form new examples.

[0161] Example 23, Preparation of 70% Compound A2 Water Dispersible Granules

[0162] According to the formula requirements, add 70 parts of compound A2, 1 part of wetting agent Morwet EFW, 4 parts of dispersant PICO-SF3, 5 parts of dispersant YUS-WG5, 3 parts of sodium salt of alkylnaphthalenesulfonic acid polycondensate, 2 parts of soluble starch, 5 parts of sodium sulfate, and bentonite to 100%, mix and grind, add water and knead, and add to a granulator equipped with a certain specification of screen for granulation. Then dry and screen (according to the range of the screen) to obtain 70% compound A2 water dispersible granules.

[0163] A2 can also be replaced with the triazolinone ether compound (as shown in general formula I) A1 or A3 described in this specification to form a new embodiment.

[0164] Example 24: Preparation of 10% Compound A1 Aqueous Solution

[0165] According to the formula requirements, add 10 parts of compound A1, 5 parts of emulsifier 2201, 5 parts of emulsifier NP-10, 5 parts of methanol, and water to 100% into a mixing kettle, stir and mix evenly, and heat in a hot water bath to dissolve if necessary to obtain a 10% compound A1 aqueous solution.

[0166] A1 can also be replaced with the triazolinone ether compound (as shown in general formula I) A2 or A3 described in this specification to form a new embodiment.

[0167] Example 25, Preparation of 50% Compound A3 Wettable Powder

[0168] According to the formula requirements, 50 parts of compound A3, 2 parts of sodium dodecyl sulfate, 5 parts of dispersant PICO-SWP1, 3 parts of polycarboxylate dispersant GY-D02, 2 parts of dispersant SK-21K, 5 parts of white carbon black, and diatomaceous earth are added to 100% and fully mixed. After being crushed by an ultra-fine grinder, a 50% compound A3 wettable powder is obtained.

[0169] A3 can also be replaced with the triazolinone ether compound (as shown in general formula I) A1 or A2 described in this specification to form a new embodiment.

[0170] Example 26, Preparation of 10% Compound A2 Emulsifiable Powder

[0171] ​​According to the formulation requirements, add 10 parts of compound A2, 3 parts of emulsifier PICO-LOE, 5 parts of emulsifier OX-2681, 2 parts of emulsifier 1601#, 5 parts of emulsifier 0201B, 5 parts of N-methylpyrrolidone, and 15 parts of Rhodiasolv Green 25 into the mixing kettle respectively, stir and mix evenly, and heat and dissolve with a hot water bath if necessary. Under stirring conditions, spray the above oil base evenly onto the mixture composed of 20 parts of silica white and attapulgite supplemented to 100%. After being pulverized by an ultrafine pulverizer, 10% compound A2 emulsifiable powder can be obtained.

[0172] Compound A2 can also be replaced with triazolinone ether compounds (such as those shown in general formula I) A1 or A3 described in this specification to form new examples.

[0173] Example 27, Preparation of 10% Compound A3 Emulsifiable Granules

[0174] According to the formulation requirements, add 10 parts of compound A3, 2 parts of emulsifier S-80, 6 parts of emulsifier OX-2681, 4 parts of emulsifier 0201B, 2 parts of emulsifier OX-8686, 5 parts of N-methylpyrrolidone, and 15 parts of Rhodiasolv Green 25 into the mixing kettle respectively, stir and mix evenly, and heat and dissolve with a hot water bath if necessary. Under stirring conditions, spray the above oil base evenly onto the mixture composed of 20 parts of silica white and attapulgite supplemented to 100%. After being pulverized by an ultrafine pulverizer, knead with water, and then add it into a granulator equipped with a certain specification sieve for granulation. Then, after drying and screening (according to the sieve range), 10% compound A3 emulsifiable granules can be obtained.

[0175] Compound A3 can also be replaced with triazolinone ether compounds (such as those shown in general formula I) A1 or A2 described in this specification to form new examples.

[0176] Example 28, Preparation of 5% Compound A2 Tablets

[0177] According to the formulation requirements, fully mix 5 parts of compound A2, 3 parts of methylnaphthalenesulfonate formaldehyde condensate, 4 parts of dispersant PICO-SF1, 1 part of emulsifier YUS-A51G, 3 parts of dispersant TANEMUL DA266, 20 parts of soluble starch, 10 parts of sodium sulfate, 5 parts of silica white, and diatomaceous earth supplemented to 100%. After being pulverized by an ultrafine pulverizer, press into tablets to obtain 5% compound A2 tablets.

[0178] Compound A2 can also be replaced with triazolinone ether compounds (such as those shown in general formula I) A1 or A3 described in this specification to form new examples.

[0179] Example 29, Preparation of 20% Compound A2 Microcapsule Suspension

[0180] According to the formulation requirements, weigh a certain proportion of urea, 37% - 40% aqueous formaldehyde solution (formaldehyde: water = 1:1.75 v / v), and appropriate amount of water and add them into a three-necked flask respectively. Adjust the pH value of the system to 8 - 9 with 10% sodium hydroxide. Under the stirring condition of 200 r / min, heat up to 70 °C and react for 1.5 h to obtain an aqueous solution of urea-formaldehyde resin prepolymer (UF). At room temperature, dissolve 22.3 g of compound A2 in a beaker with a mixture of 3 g of N-methylpyrrolidone and 2.0 g of xylene, add appropriate amount of 5% styrene maleic anhydride and a few drops of defoamer SAG1522. After stirring well, add 18 g of UF aqueous solution and stir at a speed of 2500 r / min for 30 min to form a stable O / W emulsion. Stir at a speed of 1000 r / min, slowly add 10% hydrochloric acid to adjust the pH value of the system. When the pH value drops to 2.0, reduce the rotation speed to 200 r / min, raise the temperature to 60 °C, cure for 5 h, then adjust the pH value of the system to 7 with 10% sodium hydroxide and add water to make up to 100 g and stir evenly to obtain a 20% compound A2 microcapsule suspending agent.

[0181] A2 can also be replaced with triazolinone ether compounds (such as shown in general formula I) A1 or A3 described in this specification to form new examples.

[0182] Example 30. Preparation of 5% compound A3 sustained-release granules

[0183] According to the formulation requirements, add 5 parts of compound A3, 2 parts of calcium lignosulfonate, 3 parts of sodium salt of alkylnaphthalenesulfonic acid condensate, 4 parts of sodium methylnaphthalenesulfonate formaldehyde condensate, 1 part of wetting agent EFW, 5 parts of white carbon black, 5 parts of soluble starch, 1 part of 1% chitosan aqueous solution, and bentonite to make up to 100% together, mix and pulverize, then after adding water and kneading, add it into a granulator equipped with a certain specification sieve mesh for granulation. Then dry and screen (according to the sieve mesh range), and then coat with 1 part of 1% chitosan aqueous solution and air dry to obtain 5% compound A3 sustained-release granules.

[0184] A3 can also be replaced with triazolinone ether compounds (such as shown in general formula I) A1 or A2 described in this specification to form new examples.

[0185] Example 31. Preparation of 15% compound A1 effervescent granules

[0186] According to the formula requirements, 15 parts of compound A1, 3 parts of dispersant TANEMUL AG281, 3 parts of dispersant PICO-SWP1, 2 parts of methylnaphthalenesulfonate formaldehyde condensate, 1 part of sodium dodecyl sulfate, 20 parts of soluble starch, 15 parts of citric acid, 15 parts of sodium bicarbonate, 10 parts of sodium sulfate, and diatomaceous earth are added to make up 100% and mixed thoroughly. After being pulverized by an ultrafine pulverizer and then kneaded and granulated, 15% compound A1 effervescent granules can be obtained.

[0187] A1 can also be replaced with one of the triazolinone ether compounds (such as those shown in general formula I) A2 or A3 described in this specification to form new examples.

[0188] Comparative Example 1. Preparation of 5% compound A1 emulsifiable concentrate

[0189] According to the formula requirements, 5 parts of compound A1, 5 parts of emulsifier 0201B, 5 parts of emulsifier 0203B, 2 parts of methanol, and Rhodiasolv Green SV-92 are added to make up 100% and put into a mixing kettle, stirred and mixed evenly. When necessary, it is heated and dissolved in a hot water bath to obtain 5% compound A1 emulsifiable concentrate. The determination results of physical properties: emulsion stability (standard hard water, 200 times), the emulsifying and dispersing property is poor, and there is more floating oil on the dilution liquid.

[0190] Comparative Example 2. Preparation of 10% compound A1 soluble concentrate

[0191] According to the formula requirements, 10 parts of compound A1, 6 parts of emulsifier 2201, 3 parts of emulsifier 600#, 2 parts of emulsifier 1601, 20 parts of Armid FMPC, and triethyl phosphate are added to make up 100% and mixed evenly. When necessary, it is heated and dissolved in a hot water bath to prepare 10% compound A1 soluble concentrate. After heat storage, demulsification occurs and the emulsifying and dispersing property is not good.

[0192] Comparative Example 3. Preparation of 10% compound A1 dispersible oil suspension

[0193] According to the formula requirements, 10 parts of compound A1, 5 parts of emulsifier 0201B, 2 parts of emulsifier 500#, 3 parts of emulsifier AE0-3, 2 parts of emulsifier 1601, 1 part of silica white, and methyl oleate are added to make up 100% and added to the mixing tank in sequence for mixing. First, it is coarsely pulverized and homogenized by high shear, and then pumped into a sand mill for fine grinding. The particle size of the sand mill material is detected by a particle size distribution analyzer. When the particle size reaches the standard requirements, it is filtered to obtain 10% compound A1 dispersible oil suspension. Suspension rate: 82%, the dispersion stability is acceptable. After heat storage, the dispersion stability is poor, severe stratification occurs, bottom settlement occurs, and the suspension rate is low.

[0194] Comparative Example 4. Preparation of 10% compound A1 suspension

[0195] According to the formula requirements, add 10 parts of compound A1, 2 parts of sodium methylnaphthalenesulfonate formaldehyde condensate, 4 parts of sodium alkylnaphthalene sulfonate condensate, 4 parts of emulsifier 0201B, 0.8 part of magnesium aluminum silicate, 0.8 part of silica white, 0.1 part of xanthan gum, 0.2 part of EQ, 5 parts of ethylene glycol, 0.5 part of defoamer SAG1522, and make up the volume to 100 parts with water. Add them to the mixing tank in sequence and mix. First, conduct rough crushing and homogenization through high shear, and then pump it into a sand mill for fine grinding. Use a particle size distribution analyzer to detect the particle size of the sand-milled material. After the particle size reaches the standard requirements, filter it to obtain a 10% suspension of compound A1. The suspension rate is 80%, the dispersion stability is acceptable. After heat storage, the dispersion stability is poor, severe stratification occurs, bottom settling appears, and the suspension rate is low.

[0196] Comparative Example 5. Preparation of 10% compound A1 emulsion in water

[0197] According to the formula requirements, add 10 parts of compound A1, 5 parts of emulsifier 0201B, 2 parts of emulsifier T-20, 4 parts of emulsifier 1601, 10 parts of Armid FMPC, and 15 parts of solvent oil S-150 to the mixing kettle, stir and mix to dissolve into a uniform oil phase. Under high-speed stirring, add the remaining water (to make up to 100%) to the oil phase to obtain a 10% compound A1 emulsion in water with good dispersibility. After heat storage, the dispersion of the emulsion is not good and demulsification occurs.

[0198] Performance test examples

[0199] Example 32. Stability comparison test

[0200] Test the stability of the bactericidal preparation of the present invention, and at the same time conduct a comparative test with compound A1 prepared by the method mentioned in CN 102336744 B as a control preparation. The test results are shown in Table 1.

[0201] Preparation of the control preparation: Dissolve compound A1 with acetone (the content of acetone in the total solution does not exceed 10%), and then prepare a solution with the required concentration using a 0.1% aqueous solution of Tween 80.

[0202] Table 1. Results of stability comparison test (room temperature)

[0203]

[0204] Table 2. Results of stability comparison test (room temperature)

[0205]

[0206] As can be seen from Table 1 and Table 2, the control preparation could no longer be used after being placed at room temperature for 0.1 months; while for the preparations provided by the present invention (taking the emulsifiable concentrates and soluble solutions prepared by corresponding formulations of Example 2 and Example 15, and the oil-based suspension concentrates and suspensions prepared by corresponding formulations of Example 6 and Example 12 as examples), after being placed for 1, 6, and 12 months, the surface tension changed little, the sample stability was good, the dilution stability was good, and the average particle size (D 98 ) also changed little. This indicates that the samples of the four examples can not only meet the wetting of the liquid medicine on the target, but also have good storage stability over time. The data in the above table confirm that the preparations formulated with the adjuvant system of the present invention have good storage stability, are convenient to apply, and are conducive to the exertion of drug efficacy.

[0207] Examples of biological activity tests

[0208] Greenhouse pot biological activity test (wheat powdery mildew)

[0209] In the indoor test, the seedling pot method was used for determination. The test crops were potted in the greenhouse until the 2-3 leaf stage. Foliar spray treatment was carried out on the crop sprayer according to the designed dose. The test pathogen was inoculated 24 hours after the chemical treatment. The test materials after inoculation were incubated in a phytotron with humidity maintained. The results were investigated when the blank control without chemical application was fully diseased. The test results are shown in Table 3 and Table 4. Among them, the preparation of the control chemical can be referred to the description in the above stability comparison test

[0210] Table 3 Control effects of samples with different dosage forms on wheat powdery mildew (indoor)

[0211]

[0212] Table 4 Control effects of samples with different dosage forms on wheat powdery mildew (indoor)

[0213]

[0214] From the test results in Table 3 and Table 4, it can be seen that the activities of the samples of each example against wheat powdery mildew are higher than or equivalent to those of the control chemical. The preparation method of the control chemical is the same as before.

[0215] The preparation varieties developed by the present invention have appropriate dynamic surface tension. Their liquid medicines spread, wet, and adhere well on the target, and have a long residence time, thus promoting the rapid conduction of the active ingredient and improving the biological activity of the active component. The preparations formulated with the present invention not only improve the biological activity, reduce the dosage of the medicine, lower the cost, hit the target to the greatest extent with the least amount of medicine, but also improve the compatibility with the environment.

Claims

1. A bactericide, characterized in that: The compound represented by general formula I is mixed as an active ingredient with a pesticide acceptable carrier, and the weight percentage of the active ingredient is 1 to 99%. Where: Q is selected from Q1 or Q2 as shown below: Q is selected from Q1 or Q2; When Q is selected from Q1: R1 is selected from hydrogen, halogen, cyano, nitro, CH2CN, C1-C6 alkyl, halogenated C1-C6 alkyl or C3-C6 cycloalkyl, R2 is selected from hydrogen, C1-C6 alkyl or halogenated C1-C6 alkyl; When Q is selected from Q2: R1 is selected from halogen, C1-C6 alkyl, halogenated C1-C6 alkyl or C3-C6 cycloalkyl, R2 is selected from C1-C6 alkyl or halogenated C1-C6 alkyl; R3 is selected from halogen, cyano, nitro, hydroxy, C1-C4 alkyl, halogenated C1-C3 alkyl, C1-C3 alkoxy, halogenated C1-C3 alkoxy, C1-C3 alkylthio, C1-C3 alkylsulfonyl, unsubstituted or phenyl or phenoxy substituted by 1-5 groups independently selected from the following groups: fluorine, chlorine, bromine, nitro, cyano, trifluoromethyl, C1-C3 alkyl, C1-C3 alkoxy or halogenated C1-C3 alkoxy; R4 and R5 may be the same or different and are independently selected from hydrogen, halogen, nitro, cyano, C1-C6 alkyl, halogenated C1-C6 alkyl, C1-C6 alkoxy, halogenated C1-C6 alkoxy, C1-C6 alkylthio, C1-C6 alkylsulfonyl, unsubstituted or substituted by 1-5 groups independently selected from the following groups: halogen, cyano, nitro, CO2 (C1-C4 alkyl), C1-C6 alkyl, halogenated C1-C6 alkyl, C1-C6 alkoxy, halogenated C1-C6 alkoxy, C1-C6 alkylthio or C1-C6 alkylsulfonyl; Y is selected from halogen, OR6, SR6, SOR6, SO2R6 or NHR6; R6 is selected from hydrogen or C1-C4 alkyl; Or a salt of the compound represented by general formula I.

2. The fungicide according to claim 1, characterized in that: In the compound represented by the general formula I: Q is selected from Q1 or Q2; When Q is selected from Q1: R1 is selected from hydrogen, fluorine, chlorine, bromine or C1-C4 alkyl, R2 is selected from hydrogen or C1-C6 alkyl; When Q is selected from Q2: R1 is selected from C1-C4 alkyl, R2 is selected from C1-C6 alkyl; R3 is selected from halogen, cyano, nitro, C1-C4 alkyl, halogenated C1-C3 alkyl, C1-C3 alkoxy, halogenated C1-C3 alkoxy or C1-C3 alkylsulfonyl; n＝0-3； R4 and R5 may be the same or different and are independently selected from hydrogen, fluorine, chlorine, bromine, nitro, cyano, C1-C4 alkyl, halogenated C1-C4 alkyl, C1-C4 alkoxy or halogenated C1-C4 alkoxy; Y is selected from Cl, OR6 or SR6; R6 is selected from C1-C4 alkyl; or a salt formed by a compound of formula I and hydrochloric acid, sulfuric acid, phosphoric acid, formic acid, acetic acid, trifluoroacetic acid, oxalic acid, methanesulfonic acid, p-toluenesulfonic acid, benzoic acid, phthalic acid, maleic acid, fumaric acid, sorbic acid, malic acid or citric acid.

3. The fungicide according to claim 2, characterized in that: In the compound represented by the general formula I: Q is selected from Q2; R1 and R2 are both selected from methyl; R3 is selected from fluorine, chlorine, bromine, cyano, nitro, methyl, ethyl, isopropyl, tert-butyl, CF3, CH3O or CF3O; n＝0-3； R4 and R5 may be the same or different and are selected from hydrogen, fluorine, chlorine, bromine, methyl, ethyl or isopropyl; Y is selected from Cl or CH3O; or a salt formed by a compound of formula I and hydrochloric acid, sulfuric acid, phosphoric acid, formic acid, acetic acid, trifluoroacetic acid, oxalic acid, methanesulfonic acid, p-toluenesulfonic acid, benzoic acid, phthalic acid, maleic acid, fumaric acid, sorbic acid, malic acid or citric acid.

4. The fungicide according to claim 3, characterized in that: In the compound represented by the general formula I: Q is selected from Q2; R1 and R2 are both selected from methyl; R3 is selected from fluorine or chlorine; n = 0 or 1; R4 and R5 are both selected from hydrogen; Y is selected from CH3O; or a salt formed by a compound of formula I and hydrochloric acid, sulfuric acid, phosphoric acid, formic acid, acetic acid, trifluoroacetic acid, oxalic acid, methanesulfonic acid, p-toluenesulfonic acid, benzoic acid, phthalic acid, maleic acid, fumaric acid, sorbic acid, malic acid or citric acid.

5. The bactericide according to any one of claims 1 to 4, characterized in that: The fungicide is formulated into emulsifiable concentrate, aqueous solution, water emulsion, microemulsion, soluble solution, wettable powder, suspension, dispersible oil suspension, granule, water dispersible granule, emulsifiable powder (or granule), effervescent granule (or tablet), microcapsule suspension or sustained-release granule.

6. The fungicide according to claim 5, characterized in that: The emulsifiable concentrate comprises, by weight percentage, 5-80% active ingredient, 5-20% surfactant, and the balance carrier; The aqueous solution comprises, by weight percentage, 10-50% active ingredient, 2-15% emulsifier, 0-20% other additives, and the balance water; The aqueous emulsion comprises, by weight percentage, 5-40% active ingredient, 5-25% surfactant, 5-20% solvent, and the balance water; The microemulsion comprises, by weight percentage, 5-30% active ingredient, 10-30% surfactant, 5-25% solvent, and the balance water; The soluble solution comprises, by weight percentage, 5-25% active ingredient, 8-20% surfactant, and the balance carrier; The suspending agent comprises, by weight percentage, 5-60% active ingredient, 5-20% surfactant, and the balance water carrier; The dispersible oil suspension comprises, by weight percentage, 5-50% active ingredient, 5-25% surfactant, and the balance oil-based carrier; The emulsifiable powder (or granule) comprises, by weight percentage, 1 to 30% of active ingredient, 10 to 40% of surfactant, 0 to 15% of organic solvent, and the balance of carrier; The effervescent granules (or tablets) contain, by weight percentage, 0.5-30% active ingredient, 2-15% surfactant, and the balance carrier; The sustained-release granules contain, by weight percentage, 0.5-10% active ingredient, 2-10% surfactant, and the remainder carrier; The granules contain 0.1-10% active ingredient, a small amount of water, and the balance of carrier by weight; The water dispersible granules contain, by weight percentage, 0.5-75% of active ingredient, 5-20% of surfactant, and the balance of inert carrier; The wettable powder contains, by weight percentage, 10-85% of active component, 3-10% of dispersant and the balance of solid inert carrier.

7. Use of the bactericide according to claim 1, characterized in that: The fungicide is used for preventing and controlling diseases such as wheat powdery mildew, cucumber powdery mildew, and wheat rust.

8. The use of the bactericide according to claim 7, characterized in that: The fungicide preparation is applied to the disease to be controlled and the medium where it grows at 10-1000 g of active component / hectare.

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