Binocular unequal image detection system giving consideration to central adjustment

Abstract

The invention relates to the field of ophthalmology measurement, in particular to a binocular unequal image detection system giving consideration to central adjustment. Aiming at the problem that a traditional detection tool is poor in detection repeatability due to visual center adaptability adjustment interference, the system remarkably improves the detection precision by adjusting the size of a non-dominant eye side sighting mark in stages and combining multiple times of measurement and mean value calculation. On the basis of keeping the two eyes of a detected person equal in image, non-dominant-eye sighting marks are continuously amplified or reduced, the upper limit and the lower limit of unequal-image magnification are obtained, and the average value of the upper limit and the lower limit is calculated to serve as a final detection value. Compared with a traditional method, the detection error is reduced by 50%, the visual center adjusting frequency can be reduced through the isochromatic lens designed based on the mean value, and asthenopia is effectively relieved.

Description

Technical Field

[0001] The present invention relates to the field of ophthalmic measurement, and more particularly, to a binocular aniseikonia detection system that takes into account central regulation. Background Art

[0002] Binocular aniseikonia, also known as binocular anisometropia, aniseikonia, image anisometropia or binocular image difference, refers to the unequal size or different shapes of the retinal images of the two eyes.

[0003] Among current binocular aniseikonia detection tools, whether it is the Maddox rod + two-point light source, clip-on aniseikonia correction lenses, binocular aniseikonia detection atlases, integrated refraction table doorframe visual targets, computer aniseikonia detectors or spatial aniseikonia meters (see reference [1]), there is generally a problem of poor repeatability of detection results. In addition to problems with patient cooperation and understanding during the examination, when using these detection tools, the interference of the adaptive aniseikonia adjustment mechanism of the subject's visual central system on the detection results is the main reason for the poor repeatability of the detection results.

[0004] In the case where the adaptive aniseikonia adjustment mechanism of the visual central system is involved, what can be perceived by the subject as "equal images of the two eyes" is not a single aniseikonia magnification value, but an aniseikonia magnification range.

[0005] In addition, the book "Clinical Management of Binocular Vision" (see document [1]) describes that the aniseikonia detector "measures twice in each direction, once starting from a preset -25% aniseikonia and once starting from a preset +25% aniseikonia", and "the average value of these two measurement values is the aniseikonia value". Since the preset difference in the size of the binocular visual targets is too large and the detection starts from the detection starting point where the binocular fusion state is disrupted (referring to the binocular fusion stimulation of the overall detection interface and the surrounding reference objects), it not only violates the laws of visual physiology, but also generates an adaptive inertia of the visual central system, resulting in excessive test errors.

[0006] Traditional binocular aniseikonia detection tools only pursue the randomness of a single aniseikonia magnification value when the subject perceives equal images of the two eyes. This aniseikonia magnification value is directly used to design aniseikonia lenses or improve the fusible properties of the images of the two eyes in the XR system. To a certain extent, it still relies on the frequent participation of the aniseikonia adjustment mechanism of the visual central system and still causes visual discomfort.

[0007] In addition, the latest research in visual neuroscience shows that when there is aniseikonia between the two eyes, the prefrontal cortex suppresses the signals of the non-dominant eye through theta-band oscillations (see reference [2], especially page 3152). It is proved that the visual central system preferentially takes the image of the dominant eye as the reference, and adjusts the image of the non-dominant eye through neural signal gain adjustment, so as to reduce the size difference between the image of the non-dominant eye and the image of the dominant eye. Traditional binocular aniseikonia detection tools do not distinguish between the dominant eye and the non-dominant eye, and there is no selective emphasis on the recognition, comparison, and adjustment of the detection targets between the two eyes. Obvious errors will also occur due to the differences in the regulatory mechanisms of the visual central systems of the dominant eye and the non-dominant eye.

[0008] References: [1] Li Lihua et al., "Clinical Management of Binocular Vision", People's Medical Publishing House, 2022. [2] M. S. Banks, W. J. Kim, and A. Ghosh, "Neural mechanisms of aniseikonia tolerance in human stereopsis," *Journal of Neuroscience*, vol. 43, no. 17, pp. 3146–3159, May 2023. Summary of the Invention

[0009] In order to overcome at least one of the above-mentioned defects (deficiencies) of the prior art, the present invention provides a binocular aniseikonia detection system that takes into account central regulation; this system obtains detection data by adjusting the size and shape of the target on the non-dominant eye side, and obtains the aniseikonia detection value by calculating the mean value in the way of obtaining the aniseikonia magnification range through testing.

[0010] To achieve the above object, the present invention provides a binocular aniseikonia detection system that takes into account central regulation, including a detection target display module and a target adjustment module. The system performs the following operations:

[0011] (1) Use the detection target display module to achieve binocular dissociation, present the targets to the left eye and the right eye respectively, and ensure that the sizes of the comparison parts of the targets in the two eyes are equal in the initial state;

[0012] (2) The subject compares and observes the sizes of the comparison parts of the targets in the two eyes, and adjusts the display size of the target on the non-dominant eye side through the target adjustment module until the subject observes that the sizes of the comparison parts of the targets in the two eyes are the same, and record the initial aniseikonia magnification value at this time;

[0013] The initial aniseikonia magnification value is the size adjustment ratio of the target on the non-dominant eye side relative to the target on the dominant eye side;

[0014] (3) Starting from the initial aniseikonia magnification value, while keeping the display size of the non-dominant eye's visual target at the size when the initial aniseikonia magnification value is used, conduct a second round of measurement. Through the visual target adjustment module, enlarge the display size of the non-dominant eye's visual target until the size of the comparison part of the non-dominant eye's visual target observed by the subject is larger than the size of the comparison part of the dominant eye's visual target, and obtain the upper limit value of the binocular aniseikonia magnification; through the visual target adjustment module, reduce the display size of the non-dominant eye's visual target until the size of the comparison part of the non-dominant eye's visual target observed by the subject is smaller than the size of the comparison part of the dominant eye's visual target, and obtain the lower limit value of the binocular aniseikonia magnification;

[0015] (4) Obtain the binocular aniseikonia magnification value according to the following formula:

[0016] Binocular aniseikonia magnification value = (upper limit value of binocular aniseikonia magnification + lower limit value of binocular aniseikonia magnification) / 2.

[0017] Further, there are alignment reference points on both of the binocular visual targets. In the case where the subject has strabismus, align the alignment reference points of the left and right eye visual targets.

[0018] Further, the colors, brightness, and saturation of the binocular visual targets are the same.

[0019] Further, repeat step (3) to obtain the upper limit value of the binocular aniseikonia magnification and the lower limit value of the binocular aniseikonia magnification multiple times; calculate the average value of the upper limit value of the binocular aniseikonia magnification through multiple upper limit values of the binocular aniseikonia magnification, and calculate the average value of the lower limit value of the binocular aniseikonia magnification through multiple lower limit values of the binocular aniseikonia magnification; Binocular aniseikonia magnification value = (average value of the upper limit value of the binocular aniseikonia magnification + average value of the lower limit value of the binocular aniseikonia magnification) / 2.

[0020] In addition, when the subject has monocular suppression, achieve the perceptibility of the binocular visual targets through at least one of the following methods: increasing the brightness or contrast of the visual target on the side of the suppressed eye; reducing the brightness or contrast of the visual target on the side of the dominant eye; making the visual target on the side of the dominant eye blink; or making the binocular visual targets blink alternately.

[0021] Preferably, the visual target adjustment method of the visual target adjustment module is achieved through at least one control method among mouse drag control, handle control, joystick control, touch screen drag control, voice interaction command control, motion capture control, tactile feedback control, eye tracking control, myoelectric simulation control, and gesture tracking control.

[0022] Preferably, the realization of the binocular split vision state in the detection visual target display module uses at least one method among shutter 3D glasses binocular split vision, red-green color difference 3D glasses binocular split vision, red-blue color difference 3D glasses binocular split vision, polarized light 3D glasses binocular split vision, virtual reality helmet binocular split vision, and virtual reality glasses binocular split vision.

[0023] Compared with the prior art, the beneficial effects of the technical solution of the present invention are as follows:

[0024] 1. By adjusting the visual target on the non-dominant eye side rather than the visual target on the dominant eye side, the detection result obtained by this system is closer to the adaptive adjustment mechanism of the human visual center when there is aniseikonia between the two eyes;

[0025] 2. Compared with traditional binocular aniseikonia detection tools that mainly detect a single aniseikonia magnification value when the subject perceives that the images of the two eyes are equal, this system adjusts the visual target size and visual target form when the subject perceives that the images of the two eyes are equal, and obtains an aniseikonia magnification range, which is an extension of the quantitative detection content of binocular aniseikonia;

[0026] 3. The binocular aniseikonia magnification value calculated based on the aniseikonia range value obtained by this system is used to design aniseikonia lenses, which can reduce the intensity and frequency of the participation of the aniseikonia adjustment mechanism of the visual center system, and thus generate a better binocular fusion visual comfort;

[0027] 4. Compared with the adaptive inertia of the visual center system caused by the too large difference in the visual target sizes of the two eyes preset by traditional aniseikonia detectors, which leads to too large test errors, this system adjusts the visual target size and visual target form when the subject perceives that the images of the two eyes are equal, and measures the aniseikonia magnification range under the full participation of the binocular fusion mechanism and the aniseikonia adjustment mechanism of the visual center system, which is more in line with the visual physiological law;

[0028] 5. Through 50 cases of clinical tests, the repeatability error of the detection result of this system is ±0.5%, which is significantly lower than ±2.1% of the traditional method; Description of the Drawings

[0029] Figure 1 It is a schematic diagram of the left eye visual target during vertical aniseikonia detection.

[0030] Figure 2 It is a schematic diagram of the right eye visual target during vertical aniseikonia detection.

[0031] Figure 3 It is a schematic diagram of the positional relationship between the left eye visual target and the right eye visual target displayed on the detection interface during vertical aniseikonia detection.

[0032] Figure 4 It is a schematic diagram of the forms of the right eye visual target and the left eye visual target observed by the subject during vertical aniseikonia detection.

[0033] Figure 5 It is a schematic diagram of the positional relationship between the left eye visual target and the right eye visual target displayed on the detection interface during horizontal aniseikonia detection.

[0034] Figure 6It is a schematic diagram of the positional relationship between the left-eye target and the right-eye target displayed on the detection interface during the detection of aniseikonia in the 45-degree meridian direction.

[0035] Figure 7 It is a schematic diagram of the positional relationship between the left-eye target and the right-eye target displayed on the detection interface during the detection of aniseikonia in the 135-degree meridian direction. Specific implementation mode

[0036] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the scope of protection of the present invention. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely represents selected embodiments of the present invention.

[0037] Implementation tools: Wireless 3D stereoscopic glasses (NVIDIA 3D VISION Pro 2nd generation), Asustek Computer, ASUS liquid crystal display (LCD MONITOR VG278, 27-inch TN liquid crystal display, the aspect ratio of the display screen is 16:9, the resolution is 1920*1080, supports 3D display, screen length * width = 597.73mm×336.22mm), Logitech G502 RGB wired optical mouse, computer measurement program written in JavaScript language, and an online and local database management system is built to retain the detection data and information of the detected person.

[0038] Before the person to be examined undergoes this examination, first confirm the dominant eye (the non-dominant eye is the other eye) at the subsequent detection viewing distance (the required viewing distance is 40 cm) through the WORTH four-point chart examination, that is, after wearing their own glasses, wear red-green anaglyph glasses and judge the color of the white target in the WORTH four-point chart to determine the dominant eye. And enter the information of the dominant eye and the non-dominant eye into the computer measurement program.

[0039] For the convenience of example description, assume that the dominant eye of the person to be examined at a viewing distance of 40 cm is the left eye. That is, the right eye of the person to be examined is the non-dominant eye. Additionally, it should be noted that the refractive powers of the two eyes of the person to be examined are: -3.50DS for the right eye and -0.50DS for the left eye, and the refractive error between the two eyes is 3.00DS; after wearing ordinary frame glasses, they feel a large difference in the size of the images seen by the two eyes (aniseikonia) and obvious fatigue.

[0040] Figure 1 It is a schematic diagram of the left-eye target during the detection of vertical aniseikonia.

[0041] After the measurement program is started, the background of the screen interface is uniformly light gray; the left-eye visual target 1 is a light blue semi-circle without a border, and its screen display diameter is 80 mm; the comparison line segment 2 is a straight line segment on the left-eye visual target 1 that passes through the center of the semi-circle of the left-eye visual target 1 and connects the two sides of its edge, and is used as the comparison part for aniseikonia detection; the alignment reference point 3 is the alignment reference point on the left-eye visual target 1, which is a black ring with a diameter of 10 mm and no filling color.

[0042] Figure 2 It is a schematic diagram of the right-eye visual target during vertical aniseikonia detection.

[0043] The right-eye visual target 4 is a light blue semi-circle without a border, and its screen display diameter is 80 mm.

[0044] The comparison line segment 5 is a straight line segment on the right-eye visual target that passes through the center of the semi-circle of the right-eye visual target 4 and connects the two sides of its edge, and is used as the comparison part for aniseikonia detection; the alignment reference point 6 is the alignment reference point on the right-eye visual target 4, which is a black ring with a diameter of 10 mm and no filling color.

[0045] Figure 3 It is a schematic diagram of the positional relationship between the left-eye visual target and the right-eye visual target displayed on the detection interface during vertical aniseikonia detection.

[0046] Among them, the left-eye visual target 1 and the right-eye visual target 4 are displayed simultaneously, and binocular dissociation is achieved through 3D screen display and the subject wearing 3D glasses, that is, the subject can only see the left-eye visual target 1 with the left eye and the right-eye visual target 2 with the right eye. The comparison line segment 2 and the comparison line segment 5 are parallel to each other and aligned at the upper and lower ends, which is convenient for the subject to compare the heights of the two; at this time, the two-dimensional positional relationship of the alignment reference points on the left-eye visual target 1 and the right-eye visual target 4 overlaps.

[0047] When the subject has a strabismus problem (such as esophoria), the left-eye visual target 1 and the right-eye visual target 4 observed by the subject will show ipsilateral displacement - that is, the left-eye visual target 1 is more to the left and the right-eye visual target 4 is more to the right; at this time, the distance between the comparison line segment 2 and the comparison line segment 5 observed by the subject is larger than the distance displayed on the screen, and the alignment reference points on the left-eye visual target 1 and the right-eye visual target 4 no longer overlap, but are separated left and right. At this time, by operating the left and right arrow keys on the keyboard, the horizontal position of the right-eye visual target 4 can be moved so that the two-dimensional positional relationship of the alignment reference points on the left-eye visual target 1 and the right-eye visual target 4 overlaps, thereby compensating for the perceptual eye position deviation and facilitating the comparison of the two eye visual targets.

[0048] When the subject has strabismus in other directions, the visual target can also be moved in this way for eye position compensation.

[0049] When the subject has monocular suppression (such as monocular suppression of the right eye of the patient), that is, after the subject wears their own glasses and puts on the 3D glasses, they can only see the left eye target 1 and cannot see the right eye target 4. By operating the keyboard commands, increasing the brightness and contrast of the right eye target 4 (contrast refers to the contrast between the target and the interface background), or reducing the brightness and contrast of the left eye target 1 (weakening the left eye target 1), the purpose of enhancing the right eye target 4 (the right eye is the suppressed eye) can be achieved. After the right eye target 4 is enhanced (and / or the left eye target 1 is weakened), the subject can generally observe the simultaneous presence of the left and right eye targets.

[0050] If after the right eye target 4 is enhanced (and / or the left eye target 1 is weakened), the subject still cannot observe the left and right eye targets simultaneously, the left eye target 1 can be made to blink (once every 0.5 seconds) through keyboard command operations, that is, the left eye target 1 is intermittently visible. During the interval when the left eye target 1 disappears, the right eye target 4 will be visible. The left eye target 1 and the right eye target 2 can also be made to blink alternately once every 0.5 seconds to achieve the simultaneous perceptibility of the two eye targets.

[0051] The colors of the left eye target 1 and the right eye target 4 are both light blue, and their saturation, hue, and brightness are the same. The reason for designing the two eye targets with the same HSB color space parameters is to reduce the different size adjustment effects of the visual center on targets of different colors - for targets of the same size and shape, warm-color targets look larger than cold-color targets; high-saturation targets look larger than low-saturation targets; and brighter targets look larger than darker targets.

[0052] Figure 4 It is a schematic diagram of the shapes of the left eye target and the right eye target observed by the subject during vertical aniseikonia detection.

[0053] After the subject wears their own glasses and puts on the 3D glasses, they feel that the right eye target 4 is smaller than the left eye target 1. At this time, the subject feels that the comparison line segment 5 is shorter than the comparison line segment 2 in height.

[0054] Adjust the size of the right eye target 4 using the up and down arrow keys on the keyboard. The up arrow key enlarges the target size, and the down arrow key reduces the target size. Each time the arrow key is pressed, the target size can be scaled proportionally by 0.2%.

[0055] After pressing the up arrow key 33 times, that is, after the size of the right eye target 4 is enlarged by 6.6%, the subject feels that the height of the comparison line segment 5 is the same as that of the comparison line segment 2. At this time, record the initial vertical aniseikonia magnification as: the right eye image is enlarged by 6.6%.

[0056] Then, the second round of measurement is carried out, that is, the aniseikonia range measurement is performed. At the start of the second round of measurement, the starting size of the right eye target 4 is 6.6% larger than the initial size during the detection.

[0057] The examiner explains the process and cooperation methods of the second round of measurement to the examinee. Specifically as follows:

[0058] The examinee opens both eyes, maintains concentration, keeps the head position stable, and stares at the left and right eye targets on the screen interface. After starting the second round of measurement by pressing the Enter key on the keyboard, the right-eye target 4 will gradually become larger (increasing by 0.1% every 200 milliseconds). When the examinee feels that the height of the comparison line segment 5 is greater than that of the comparison line segment 2, quickly press the Space key on the keyboard to confirm the upper limit value of the aniseikonia magnification. After that, press the Enter key on the keyboard, and the right-eye target 4 will gradually become smaller (decreasing by 0.1% every 200 milliseconds). Continue to observe the heights of the comparison line segment 5 and the comparison line segment 2. When the examinee feels that the height of the comparison line segment 5 is less than that of the comparison line segment 2, quickly press the Space key on the keyboard to confirm the lower limit value of the aniseikonia magnification. Measure in this cycle 6 times, that is, press the Enter key 6 times and the Space key 6 times, and the right-eye target 4 has 6 consecutive size enlargements and 6 consecutive size reductions.

[0059] When the examinee observes that the height of the comparison line segment 5 is greater than that of the comparison line segment 2, there is a time delay problem in the eye-hand movement execution when the examinee presses the Space key on the keyboard. According to the law of the time delay of the ordinary person's eye-hand movement execution of 200 - 300 milliseconds, plus the visual perception lag generated by the aniseikonia adjustment mechanism of the visual central system. According to the statistics of the pre-experiment (sample size N = 30), the hand-brain-eye lag compensation value is set to 0.3%. That is, the recorded upper limit value of the aniseikonia magnification is reduced by 0.3%, and the lower limit value of the aniseikonia magnification is increased by 0.3% for hand-brain-eye lag compensation.

[0060] For these 6 measurements of the examinee, the values recorded by the system when the examinee presses the Space key are 7.3%, 5.5%, 7.2%, 5.3%, 7.4%, and 5.4% respectively. According to the above hand-brain-eye lag compensation rule, the actually measured 3 upper limit values of the aniseikonia magnification are 7.3% - 0.3% = 7.0%, 7.2% - 0.3% = 6.9%, and 7.1% - 0.3% = 7.1% respectively, and the 3 lower limit values of the aniseikonia magnification are 5.5% + 0.3% = 5.8%, 5.3% + 0.3% = 5.6%, and 5.4% + 0.3% = 5.7% respectively.

[0061] The average value of the upper limit of the vertical aniseikonia magnification of the examinee = (7.0% + 6.9% + 7.1%) / 3 = 7.0%;

[0062] The average value of the lower limit of the vertical aniseikonia magnification of the examinee = (5.8% + 5.6% + 5.7%) / 3 = 5.7%;

[0063] The vertical aniseikonia magnification value of the examinee = (the average value of the upper limit of the vertical aniseikonia magnification + the average value of the lower limit of the vertical aniseikonia magnification) / 2 = (7.0% + 5.7%) / 2 = 6.35%, that is, the right eye image is enlarged by 6.35%;

[0064] Through this anisometropia detection method of the present invention, the anisometropia state of the subject can also be described by the anisometropia magnification range, that is, the vertical anisometropia magnification range of the subject = 5.7% - 7.0%;

[0065] For this subject, compared with the initial vertical anisometropia magnification of 6.6%, after measuring the upper and lower limits of the anisometropia magnification and calculating the average value, the final vertical anisometropia magnification is 6.35%;

[0066] According to the homeostatic regulation mechanism in physiology and neuroscience, compared with the traditional anisometropia detection method, the anisometropia magnification values of the two eyes obtained by this formula calculation method are closer to the regulation target value of the anisometropia regulation mechanism of the visual central system; the subject wears anisometropic lenses designed according to the anisometropia magnification value of 6.35% obtained by this formula calculation method. Compared with the anisometropic lenses designed according to the anisometropia magnification of 6.6%, the former can trigger the anisometropia regulation mechanism of the visual central system less and improve the anisometropic visual fatigue more significantly over time.

[0067] The vertical anisometropia values of most people are equivalent to the horizontal anisometropia values. For those with astigmatism or asymmetric anisometropia problems, there are differences between the vertical anisometropia values and the horizontal anisometropia values. Both eyes of the aforementioned subject are simple myopia without astigmatism. To improve the detection efficiency, anisometropic glasses (also called aniseikonia glasses) are designed for the subject only based on the vertical anisometropia value, which can significantly relieve the anisometropic visual fatigue problem of the subject.

[0068] The above is the description of the detection and calculation process of vertical anisometropia detection. The anisometropia detection processes in other directions such as horizontal and different meridian directions are similar to the vertical anisometropia detection process and are only shown in simple diagrams. The detection processes and calculation methods will not be elaborated one by one.

[0069] Figure 5 It is a schematic diagram of the positional relationship between the left - eye visual target and the right - eye visual target displayed on the detection interface during horizontal anisometropia detection. When performing horizontal anisometropia detection, the subject needs to compare the widths of the comparison line segments 9 on the left - eye visual target 7 and 10 on the right - eye visual target 8.

[0070] Figure 6 It is a schematic diagram of the positional relationship between the left - eye visual target and the right - eye visual target displayed on the detection interface during anisometropia detection in the 45 - degree meridian direction. When performing anisometropia detection in the 45 - degree meridian direction, the subject needs to compare the lengths of the comparison line segments 13 on the left - eye visual target 11 and 14 on the right - eye visual target 12.

[0071] Figure 7It is a schematic diagram of the positional relationship between the left-eye visual target and the right-eye visual target displayed on the detection interface during the detection of aniseikonia in the 135-degree meridian direction. When performing the detection of aniseikonia in the 135-degree meridian direction, the subject needs to compare the lengths of the comparison line segments 17 on the left-eye visual target 15 and the comparison line segments 18 on the right-eye visual target 16.

Claims

1. A binocular anisotropy detection system taking into account central regulation, comprising a detection sight mark display module and a sight mark adjustment module, the system performs the following operations: (1) Use the detection sight mark display module to realize binocular vision, present sight marks to the left eye and the right eye respectively, and ensure that the size of the sight mark comparison part of the two eyes is equal in the initial state; (2) The subject compares and observes the sizes of the comparison parts of the optotypes of the two eyes, and adjusts the display size of the optotype on the non-dominant eye through the optotype adjustment module until the subject observes that the sizes of the comparison parts of the optotypes of the two eyes are consistent, and records the initial anisotropy magnification value at this time; (3) Taking the initial unequal magnification value as the starting point, keeping the display size of the non-dominant eye side sight mark at the initial unequal magnification value, further performing a second round of measurement, enlarging the display size of the non-dominant eye side sight mark through the sight mark adjustment module until the subject observes that the size of the non-dominant eye side sight mark comparison part is larger than the size of the dominant eye side sight mark comparison part, thereby obtaining the upper limit value of the two-eye unequal magnification; reducing the display size of the non-dominant eye side sight mark through the sight mark adjustment module until the subject observes that the size of the non-dominant eye side sight mark comparison part is smaller than the size of the dominant eye side sight mark comparison part, thereby obtaining the lower limit value of the two-eye unequal magnification; (4) Obtain the value of the two-eye unequal image magnification according to the following formula: The value of binocular unequal magnification = (binocular unequal magnification upper limit + binocular unequal magnification lower limit) / 2.

2. The system according to claim 1, wherein the sight marks for both eyes are provided with alignment reference points, wherein: If the subject has strabismus, the alignment reference points of the left and right eye sight marks are made to coincide with each other.

3. The system according to claim 1, characterized in that The color, brightness and saturation of the visual targets for both eyes are the same.

4. The system of claim 1, 2 or 3, wherein step (3) is repeated to obtain an upper limit value of the unequal magnification ratio of both eyes and a lower limit value of the unequal magnification ratio of both eyes for multiple times; an average value of the upper limit value of the unequal magnification ratio of both eyes is calculated by using the upper limit values ​​of the unequal magnification ratio of both eyes for multiple times, and an average value of the lower limit value of the unequal magnification ratio of both eyes is calculated by using the lower limit values ​​of the unequal magnification ratio of both eyes for multiple times; wherein: The value of the unequal magnification of both eyes = (the average of the upper limit of the unequal magnification of both eyes + the average of the lower limit of the unequal magnification of both eyes) / 2.

5. The system according to claim 1, 2 or 3, characterized in that: When the subject has monocular suppression, the perceptibility of binocular sight marks is achieved by at least one of the following methods: increasing the brightness or contrast of the sight mark on the suppressed eye side; reducing the brightness or contrast of the sight mark on the dominant eye side; flashing the sight mark on the dominant eye side; or flashing the sight marks of both eyes alternately.

6. The system according to claim 1, 2 or 3, characterized in that: The sight mark adjustment method of the sight mark adjustment module is achieved by at least one of the following control methods: mouse drag control, handle control, rocker control, touch screen drag control, voice interaction command control, motion capture control, tactile feedback control, eye tracking control, electromyography simulation control, and gesture tracking control.

7. The system according to claim 1, 2 or 3, characterized in that: The binocular dichotomy state in the detection sight mark display module is achieved by using at least one of shutter 3D glasses binocular dichotomy, red-green color difference 3D glasses binocular dichotomy, red-blue color difference 3D glasses binocular dichotomy, polarized light 3D glasses binocular dichotomy, virtual reality helmet binocular dichotomy, and virtual reality glasses binocular dichotomy.

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