A spleen-invigorating and dampness-dispelling composition of food and medicine, and a preparation method and application thereof
By combining ingredients from Codonopsis pilosula, lotus seeds, coix seeds, euryale seeds, tangerine peel, and wolfberry, the problem of insignificant symptom improvement in people with spleen deficiency and dampness is solved. This provides a combination of ingredients from Codonopsis pilosula, lotus seeds, coix seeds, euryale seeds, tangerine peel, and wolfberry that are both food and medicine, and can be prepared into oral solutions or powders to significantly improve symptoms of spleen deficiency and dampness.
Patent Information
- Application Number
- CN202510141789.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Priority Date
- 2024-07-30
- Filing Date
- 2025-02-08
- Publication Date
- 2025-11-07
- Estimated Expiration
- 2045-02-08
AI Technical Summary
Existing health supplements and herbal teas have not shown significant effects on improving symptoms in people with spleen deficiency and dampness, especially symptoms such as being overweight, feeling heavy in the hands, feet, head, or body, having a bland or astringent taste in the mouth, and having loose or undigested stools.
This product uses a combination of medicinal and edible ingredients, including Codonopsis pilosula, lotus seeds, Coix seeds, Euryale ferox, tangerine peel, and wolfberry. It is formulated to strengthen the spleen and remove dampness, while also tonifying the kidneys, astringing the intestines, and stopping diarrhea. It is prepared as an oral solution or powder and is suitable for people with spleen deficiency and dampness.
It significantly improves symptoms such as obesity, heaviness in the hands, feet, head and body, bland or astringent taste in the mouth, and loose or undigested stools in people with spleen deficiency and dampness. Moreover, the medicine is mild, does not harm yin or cause stagnation, and is suitable for long-term use.
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Abstract
Description
TECHNICAL FIELD
[0001] The present application belongs to the field of health food, and particularly relates to a medicine-food homologous composition for invigorating the spleen and expelling dampness, a preparation method and application thereof. BACKGROUND
[0002] The Lingnan region in China has a humid climate. In the Qing Dynasty, a Guangdong medical doctor, He Mengyao, mentioned in 'Yi Bie · Zhong Shi' that 'the low-lying land is particularly humid, with morning and evening fog, spring and summer rain, and many people suffer from dampness'. The dampness is caused by the damp earth and the dampness is the long summer qi. From the Dog Days to the autumnal equinox every year is the time when the spleen disease and the damp disease occur more frequently. If people stay in such a region and climate for a long time, the spleen and stomach qi is easily damaged, the phlegm and dampness is accumulated, and the symptoms of spleen deficiency with dampness such as body obesity, heavy hands and feet or head and body, tasteless or dry mouth, loose or rotten stool, etc. appear. However, 'dampness is the most common disease, many people do not feel dampness coming, but they know to avoid cold and wind, but they do not know to avoid dampness, because the harm is the most slow, the most hidden, and it is difficult to be noticed' (Yi Yuan Ji Lu). Sometimes, even if the dampness is felt, there is no related symptom, but at this time, 'prevention is better than cure'. For 'prevention is better than cure', traditional Chinese medicine advocates protecting and supporting the body's healthy qi through food, acupuncture, massage, qigong, rest adjustment and other methods.
[0003] The dampness is heavy, turbid, sticky and easy to change, and is often accompanied by other evils, which is difficult to remove. Although there are many methods to expel dampness, if the degree of expelling evil and supporting the healthy qi is not accurate, the situation of expelling evil and damaging the healthy qi or supporting the healthy qi and causing greasy and sticky may easily occur, especially for the people with spleen deficiency with dampness who have no obvious symptoms. The people with spleen deficiency with dampness generally tend to take health products or herbal teas to improve the symptoms because the symptoms are not serious. The effect of the health products or herbal teas on the market for the people with spleen deficiency with dampness is not satisfactory, and the symptoms of the people with spleen deficiency with dampness such as body obesity, heavy hands and feet or head and body, tasteless or dry mouth, loose or rotten stool, etc. cannot be obviously improved, so it is necessary to develop a health product or medicine-food homologous herbal tea which can effectively improve the symptoms of the people with spleen deficiency with dampness. SUMMARY
[0004] The first object of the present application is to provide a medicine-food homologous composition for invigorating the spleen and expelling dampness, the second object of the present application is to provide a preparation method of the medicine-food homologous composition for invigorating the spleen and expelling dampness, and the third object of the present application is to provide an application of the medicine-food homologous composition for invigorating the spleen and expelling dampness.
[0005] According to the first aspect of the present application, a medicine-food homologous composition for invigorating the spleen and expelling dampness is provided, and the raw material composition thereof includes, in mass parts, 3-30 parts of radix codonopsis, 5-40 parts of lotus seed, 10-40 parts of coix seed, 10-40 parts of gordon euryale seed, 1-15 parts of dried tangerine or orange peel, and 5-30 parts of medlar.
[0006] The present application considers that the dampness is the main cause of the disease in Lingnan area, and the disease is mainly caused by spleen deficiency combined with dampness, and the symptoms of spleen deficiency and diarrhea often occur. Although the treatment should be based on the method of invigorating the spleen and removing dampness, it should also be combined with the method of tonifying the kidney and astringing the intestine to stop diarrhea, so as to prevent the continuous diarrhea from further consuming the kidney yang. The present application is aimed at the people with spleen deficiency combined with dampness, whose main manifestations are body overweight, hands and feet or head and body heavy, tasteless or dry mouth, loose or rotten stool, etc. The present application adopts the method of TCM syndrome differentiation and treatment, and proposes the present application of the medicine-food homologous composition, which invigorates the spleen and removes dampness, and astringes the intestine to stop diarrhea, and adjusts the kidney yang at the same time.
[0007] In the prescription, Codonopsis pilosula (Franch.) Nannf. is sweet and flat in taste, and can tonify the spleen and stomach, and regulate the middle qi. Coix seed is sweet and flat in taste, and can invigorate the spleen, remove dampness and stop diarrhea. The two are the monarch herbs, and can invigorate the spleen and remove dampness. Lotus seed and Gorgon nut are sweet and astringent in taste, and flat in nature. Lotus seed can benefit the spleen and stomach, and has astringent nature, which is most suitable for people with diarrhea and spermatorrhea. Coix seed can tonify the kidney and astringe the essence, and can be used with other yin-tonifying herbs to assist in adding essence without increasing dampness. Coix seed can not only benefit the essence, but also astringe the essence and tonify the kidney. Medlar is sweet in taste, and flat in nature, and belongs to the liver, kidney and spleen channels. Medlar can tonify yin, and has yang in yin, so it can tonify qi. Therefore, medlar can tonify yin without causing yin deficiency, and can assist yang without causing yang excess. Lotus seed, Gorgon nut and medlar are the ministerial herbs, which are used with the monarch herb to remove dampness without damaging yin, and to tonify and benefit without stagnation, so as to invigorate the spleen, tonify the kidney and astringe the intestine to stop diarrhea. Pericarpium Citri Reticulatae is bitter and pungent in taste, and warm in nature, which can assist the monarch herb to invigorate the spleen and remove dampness, and can regulate qi and remove stagnation, and tonify qi to prevent stagnation. The medicine-food homologous composition of the present application is flat in nature, and invigorates the spleen and removes dampness, and removes dampness and astringes the intestine at the same time, so as to invigorate the spleen, remove dampness, tonify the kidney and astringe the intestine to stop diarrhea, and can obviously improve the clinical symptoms of people with spleen deficiency combined with dampness, such as body overweight, hands and feet or head and body heavy, tasteless or dry mouth, loose or rotten stool, etc.
[0008] The raw materials of the present application are as follows:
[0009] Codonopsis pilosula (Franch.) Nannf. is the root of Codonopsis pilosula (Franch.) Nannf., C. pilosula Nannf. var. (Nannf.) L.T. Shen or C. tangshen Oliv.
[0010] Lotus seed is the mature seed of Nelumbo nucifera Gaertn.
[0011] Coix seed is the dried mature seed of Coix lacryma jobi L. var. mayuen (Roman.) Stapf.
[0012] Gorgon nut: mature seed kernel of Euryale ferox Salisb. of Nelumbonaceae.
[0013] Dried mature pericarp of Citrus reticulata Blanco of Rutaceae and its cultivated varieties.
[0014] Gouqi: mature fruit of Lycium barbarum L. of Solanaceae.
[0015] In some embodiments, the adlay seed is stir-fried adlay seed. After being stir-fried, the cold nature of the adlay seed is removed, and the ability of strengthening the spleen, eliminating dampness and stopping diarrhea is enhanced.
[0016] In some embodiments, the dosage form of the medicinal and edible composition for strengthening the spleen and eliminating dampness is oral solution, powder or granules.
[0017] In some embodiments, food acceptable adjuvants can also be added.
[0018] In some embodiments, the adjuvant is at least one of sustained-release agent, excipient, filler, binder, humectant, disintegrating agent, absorption promoter, adsorption carrier, surface active agent, lubricant.
[0019] According to the second aspect of the present application, the preparation method of the medicinal and edible composition for strengthening the spleen and eliminating dampness is provided, when the dosage form of the medicinal and edible composition for strengthening the spleen and eliminating dampness is oral solution, the preparation method comprises the following steps:
[0020] The raw materials are soaked in 8-12 times of water by weight for 20-40 minutes, then heated to boiling, and kept boiling for 1-2 hours. The filtrate is obtained by filtering and repeating the decoction of the residue for 1-2 times. After the oral solution is cooled, it is also divided into small packages, so as to facilitate carrying and distribution.
[0021] According to the third aspect of the present application, the preparation method of the medicinal and edible composition for strengthening the spleen and eliminating dampness is provided, when the dosage form of the medicinal and edible composition for strengthening the spleen and eliminating dampness is powder, the preparation method comprises the following steps:
[0022] Each raw material is respectively crushed or chopped, then the crushed or chopped raw materials are respectively passed through 10 mesh and 50 mesh screen, the coarse particles that cannot pass through the 10 mesh screen are continuously crushed or chopped, and the powder between the 10 mesh screen and the 50 mesh screen is taken, then the raw material powders are mixed according to the ratio, and packaged in a sealed bag.
[0023] According to a fourth aspect of the present application, there is provided use of the above-mentioned spleen-invigorating and dampness-dispelling dietotherapy composition in the preparation of a dietotherapy health food for improving symptoms of spleen deficiency with dampness. Specifically, the symptoms of spleen deficiency with dampness include body obesity, heavy hands and feet or head and body, tasteless mouth, dry mouth, loose or rotten stool. The dietotherapy health food includes a dietotherapy substitute tea, a tablet, and an effervescent tablet.
[0024] The raw materials in the dietotherapy composition of the present application, including radix codonopsis, lotus seeds, coix seed, gordon euryale seed, dried tangerine or orange peel, and medlar, belong to substances that are both food and Chinese medicinal materials (Notice of the Ministry of Health on Further Standardizing the Management of Health Food Raw Materials (No. 51 of the Health Food Supervision and Management
[2002] ), Announcement on 9 Newly Added Substances That Are Both Food and Chinese Medicinal Materials According to Tradition (No. 9 of 2023)), and the raw materials for the composition all belong to Chinese medicinal materials that can be used in health food, which are safe and reliable in source.
[0025] The raw materials of the spleen-invigorating and dampness-dispelling dietotherapy composition of the present application have the characteristics of dietotherapy and safe medication, and can be prepared into dietotherapy health food such as a dietotherapy substitute tea, a tablet, and an effervescent tablet.
[0026] Illustratively, the preparation method of the dietotherapy substitute tea includes the following steps: drying radix codonopsis, lotus seeds, coix seed, gordon euryale seed, dried tangerine or orange peel, and medlar to <3.0% of water content, removing impurities and inferior raw materials, and then weighing each raw material according to the raw material ratio after ultraviolet sterilization, and mixing uniformly to obtain the dietotherapy substitute tea.
[0027] The obtained dietotherapy substitute tea is packaged with a gauze tea bag, and is used by brewing with about 100 mL of warm boiled water for drinking. The dietotherapy substitute tea of the present application has a good improvement effect on symptoms such as body obesity, heavy hands and feet or head and body, tasteless mouth, dry mouth, loose or rotten stool, etc. that occur in people with spleen deficiency with dampness, and is suitable for long-term drinking.
[0028] The present application has the following beneficial effects:
[0029] (1) The spleen-invigorating and dampness-dispelling dietotherapy composition of the present application can effectively improve symptoms such as body obesity, heavy hands and feet or head and body, tasteless mouth or dry mouth, loose or rotten stool, etc. that occur in people with spleen deficiency with dampness.
[0030] (2) The present application does not use products that are greasy, rich, and strongly invigorating, but mainly uses products that are sweet and flat, and is supplemented with qi-regulating drugs. Through ingenious compatibility, the products are invigorating without stagnation, and both the symptoms and the root cause are considered, so that the spleen is invigorated and dampness is dispelled, the kidney is also considered, and the intestines are astringed to stop diarrhea, so as to prevent excessive dampness. Clinical research shows that the spleen-invigorating and dampness-dispelling dietotherapy composition of the present application can significantly improve symptoms such as body obesity, heavy hands and feet or head and body, tasteless mouth or dry mouth, loose or rotten stool, etc. that occur in people with spleen deficiency with dampness. DETAILED DESCRIPTION
[0031] The application will be further described in conjunction with specific examples. It is to be noted that the following examples are only for better explaining the application and do not limit the scope of the application. The process steps not disclosed in the examples are the prior art. Unless otherwise specified, the following raw materials are commercially available.
[0032] Example 1
[0033] The Spleen-strengthening and Dampness-removing medicinal and food homologous oral solution of the example comprises the following raw materials: Radix Codonopsis 10 g, Lotus seed 20 g, Fried Semen Coicis 20 g, Semen Euryale 30 g, Tangerine Peel 2 g, and Fructus Lycii 10 g.
[0034] The preparation method comprises the following steps:
[0035] (1) The raw materials are soaked in 10 times by weight of water for 30 minutes, and then heated to boiling, and kept at a slight boil for 1 hour. After separation, the first decoction and the residue are obtained. The residue obtained after the first decoction is added with 8 times by weight of water based on the total mass of the raw materials, heated to boiling, and kept at a slight boil for 1 hour. After separation, the second decoction and the residue are obtained. The first decoction and the second decoction are combined to obtain the oral solution.
[0036] (2) The obtained oral solution is cooled and then packaged. The ratio is one dose, and one dose is about 150 mL.
[0037] Example 2
[0038] The Spleen-strengthening and Dampness-removing medicinal and food homologous powder of the example comprises the following raw materials: Radix Codonopsis 10 g, Lotus seed 20 g, Fried Semen Coicis 20 g, Semen Euryale 30 g, Tangerine Peel 2 g, and Fructus Lycii 10 g.
[0039] The preparation method comprises the following steps:
[0040] (1) Radix Codonopsis is crushed and passed through 10-mesh and 50-mesh sieves. The coarse particles that cannot pass through the 10-mesh sieve are further crushed. The powder located between the 10-mesh sieve and the 50-mesh sieve is taken.
[0041] (2) Lotus seed, Fried Semen Coicis, Semen Euryale, Tangerine Peel, and Fructus Lycii are crushed into powders according to the method of step (1);
[0042] (3) The powders of the raw materials are mixed uniformly, and then packaged in a sealed bag. When taken, it can be taken with about 150 mL of warm water.
[0043] Example 3
[0044] The Spleen-strengthening and Dampness-removing medicinal and food homologous oral solution of the example comprises the following raw materials: Radix Codonopsis 30 g, Lotus seed 40 g, Fried Semen Coicis 40 g, Semen Euryale 40 g, Tangerine Peel 15 g, and Fructus Lycii 30 g.
[0045] The preparation method is the same as that of Example 1.
[0046] Example 4
[0047] The raw material composition of the spleen-strengthening and dampness-removing medicinal and food homologous powder of the present example is: Radix Codonopsis 3g, Lotus seed 5g, Fried Semen Coicis 10g, Semen Euryale 10g, Tangerine Peel 1g, and Fructus Lycii 5g.
[0048] The preparation method is the same as that of Example 2.
[0049] The spleen-strengthening and dampness-removing medicinal and food homologous oral solution prepared in Example 1 is used for people with spleen deficiency combined with dampness. The administration method is: one dose per day, with a dose of about 150mL, taken twice a day in the morning and evening, and continuously taken for 7 days. The gender, age, symptom information and follow-up symptom information of 31 patients with spleen deficiency combined with dampness from August 5, 2024 to August 30, 2024 are collected, and the main symptoms are scored.
[0050] The 31 patients with spleen deficiency combined with dampness are aged 22-67 years, with an average age of 36.7 years, including 16 males and 15 females. The main symptoms before taking the medicine include heavy head and body, tasteless or dry mouth, and loose or rotten stool. The self-symptoms of the 31 patients with spleen deficiency combined with dampness before and after taking the spleen-strengthening and dampness-removing medicinal and food homologous oral solution of Example 1 are compared, and the results are shown in Table 1.
[0051] Table 1 Statistical analysis table of the effect of the spleen-strengthening and dampness-removing medicinal and food homologous oral solution on the symptoms of patients with spleen deficiency combined with dampness
[0052]
[0053] As can be seen from Table 1, the average symptom scores of the patients after taking the spleen-strengthening and dampness-removing medicinal and food homologous oral solution of the present application are lower than those before taking the medicine (P<0.05), indicating that the spleen-strengthening and dampness-removing medicinal and food homologous composition of the present application is significantly effective in improving the symptoms of patients with spleen deficiency combined with dampness, such as heavy head and body, tasteless or dry mouth, and loose or rotten stool.
[0054] The above only describes some specific embodiments of the present application. Those skilled in the art can make several modifications and improvements without departing from the inventive concept, which are all within the protection scope of the present application.
Claims
1. A pharmafood composition for strengthening the spleen and expelling dampness, characterized in that, The raw materials are composed of 3-30 parts of radix codonopsis, 5-40 parts of lotus seed, 10-40 parts of coix seed, 10-40 parts of gordon euryale seed, 1-15 parts of dried tangerine or orange peel, and 5-30 parts of medlar.
2. The spleen-invigorating and damp-dispelling pharmacologically identical composition as claimed in claim 1, wherein The coix seed is fried coix seed.
3. The spleen-invigorating and dampness-dispelling pharmacologically identical composition according to claim 1 or 2, characterized in that, The dosage form of the spleen-strengthening and dampness-removing medicinal and edible composition is oral solution, powder or granules.
4. The spleen-invigorating and dampness-expelling pharmacognosy composition according to claim 1 or 2, characterized in that, Food acceptable adjuvants can also be added.
5. The spleen-invigorating and damp-dispelling pharmacologically identical composition as claimed in claim 4, wherein The adjuvant is at least one of sustained-release agent, excipient, filler, binder, humectant, disintegrating agent, absorption promoter, adsorption carrier, surfactant, lubricant.
6. A process for the preparation of the spleen strengthening and damp eliminating medicinal and food composition as claimed in any of the claims 1 to 5, wherein, When the dosage form of the spleen-strengthening and dampness-removing medicinal and edible composition is oral solution, the preparation method comprises the following steps: The raw materials are soaked in 8-12 times of water by weight for 20-40 minutes, then heated to boiling, and kept at micro-boiling for 1-2 hours. The filtrate is obtained by filtering and repeating decocting the residue 1-2 times.
7. A process for the preparation of the spleen strengthening and damp eliminating medicinal and food composition as claimed in any of claims 1 to 5, wherein, When the dosage form of the spleen-strengthening and dampness-removing medicinal and edible composition is powder, the preparation method comprises the following steps: The raw materials are respectively crushed or cut into pieces, then the crushed or cut raw materials are respectively passed through 10-mesh and 50-mesh screen, the coarse particles that cannot pass through the 10-mesh screen are further crushed or cut into pieces, the powder between the 10-mesh and 50-mesh screens is taken, then the raw material powders are mixed according to the ratio, and packed in a sealed bag.
8. Use of the spleen-strengthening and dampness-removing medicinal and edible composition of any one of claims 1-5 in the preparation of medicinal and edible health food for improving symptoms of spleen deficiency with dampness.
9. Use according to claim 8, characterized in that, The symptoms of spleen deficiency with dampness include body obesity, heavy hands and feet or head and body, tasteless mouth, dry mouth, loose or rotten stool.
10. Use according to claim 8 or 9, characterized in that, The medicinal and edible health food includes medicinal and edible substitute tea, buccal tablets, effervescent tablets.