Pesticide composition and application thereof

Abstract

The invention discloses a pesticide composition and application thereof, the pesticide composition comprises an active component A and an active component B, the active component A is Bifemetstrobin, the active component B is any one of carbendazim, thiophanate-methyl and isoprothiolane, and the mass ratio of the active component A to the active component B is 1: 60-42: 1. The pesticide composition or the preparation thereof disclosed by the invention can enhance the pesticide effect and reduce the dosage, shows a good control effect on various plant pathogenic bacteria, has a synergistic effect under a certain mass ratio, can delay the development of pesticide resistance, and is safe to the environment.

Description

Technical Field

[0001] The present invention belongs to the technical field of pesticide compounding, and particularly relates to a pesticide composition and its application. Background Art

[0002] Rice is an important food crop. Rice blast is a highly destructive disease. If not properly controlled, it will seriously affect the rice yield and pose a serious threat to the food production safety in China. The pathogen of rice blast is Magnaporthe grisea, belonging to the genus Magnaporthe in the phylum Ascomycota. Its asexual state is Pyricularia oryzae, belonging to the genus Pyricularia in the Deuteromycetes. According to the different infection periods and parts of rice, the infection can be divided into seedling blast, leaf blast, collar blast, node blast, panicle neck blast and grain blast. Among them, the most harmful one is panicle neck blast, which may even lead to complete crop failure in severe cases.

[0003] Bifemetstrobin is a strobilurin fungicide developed by Sumitomo Chemical Co., Ltd., Japan; CAS No.: 2454319-63-0, and its chemical structure is as follows:

[0004]

[0005] At present, the main pesticides for controlling rice blast are triazoles, benzimidazoles, dithiol heterocycles, etc. Due to the long-term and irregular use of pesticides, the pathogenic bacteria have developed drug resistance, which has brought great difficulties to disease control. Compounding Bifemetstrobin with other fungicides with different action mechanisms to develop a new type of highly efficient compound agent is of great significance for overcoming and delaying the drug resistance of the bacteria, reducing the dosage of pesticides, effectively controlling the damage of rice blast, and ensuring the stable and high yield of rice. In addition, there is no report on the pesticide composition of Bifemetstrobin and carbendazim, thiophanate-methyl, isoprothiolane. Summary of the Invention

[0006] Based on the above situation, the purpose of the present invention is to provide a pesticide composition and its application. The pesticide composition or its preparation can enhance the drug effect, reduce the dosage, show good control effects on various plant pathogenic bacteria, have a synergistic effect under a certain mass ratio, and at the same time can delay the development of drug resistance and is safe for the environment.

[0007] To achieve the above purpose, the present invention adopts the following technical scheme: A pesticide composition, the pesticide composition contains active ingredient A and active ingredient B, the active ingredient A is Bifemetstrobin, and the active ingredient B is any one of carbendazim, thiophanate-methyl, isoprothiolane;

[0008] Furthermore, the mass ratio of the active ingredient A to the active ingredient B is 1:60 to 42:1;

[0009] Furthermore, the mass ratio of the active ingredient A to the active ingredient B is 1:60 to 30:1, or any value within the above numerical range;

[0010] Furthermore, the active ingredient B is carbendazim, and the mass ratio of Bifemetstrobin to carbendazim is 1:60 to 22:1;

[0011] Furthermore, the mass ratio of Bifemetstrobin to carbendazim is 1:60, 1:46, 1:24, 1:12, 1:6, 1:3, 9:1, 22:1, 42:1;

[0012] Still further, the mass ratio of Bifemetstrobin to carbendazim is 1:46 to 22:1;

[0013] Furthermore, the mass ratio of Bifemetstrobin to carbendazim is 1:46, 1:24, 1:12, 1:6, 1:3, 9:1, 22:1;

[0014] Furthermore, the active ingredient B is thiophanate-methyl, and the mass ratio of Bifemetstrobin to thiophanate-methyl is 1:42 to 28:1;

[0015] Furthermore, the mass ratio of Bifemetstrobin to thiophanate-methyl is 1:42, 1:28, 1:20, 1:15, 1:10, 10:1, 15:1, 28:1;

[0016] Still further, the mass ratio of Bifemetstrobin to thiophanate-methyl is 1:28 to 28:1;

[0017] Furthermore, the mass ratio of Bifemetstrobin to thiophanate-methyl is 1:28, 1:20, 1:15, 1:10, 10:1, 15:1, 28:1;

[0018] Furthermore, the active ingredient B is isoprothiolane, and the mass ratio of Bifemetstrobin to isoprothiolane is 1:42 to 30:1;

[0019] Furthermore, the mass ratio of Bifemetstrobin to isoprothiolane is 1:42, 1:30, 1:21, 2:25, 1:7, 8:1, 20:1, 30:1;

[0020] Further, the mass ratio of Bifemetstrobin to Isoprothiolane is 1:42 to 20:1;

[0021] Further, the mass ratio of Bifemetstrobin to Isoprothiolane is 1:42, 1:30, 1:21, 2:25, 1:7, 8:1, 20:1;

[0022] Further, based on the total weight of the pesticide composition being 100 wt%, the sum of the contents of active ingredient A and active ingredient B in the pesticide composition is 1 - 80 wt%, or any value within the above numerical range;

[0023] Further, based on the total weight of the pesticide composition being 100 wt%, the sum of the contents of active ingredient A and active ingredient B in the pesticide composition is 5 - 70 wt%, or any value within the above numerical range;

[0024] Further, the pesticide composition further comprises agriculturally acceptable auxiliary ingredients in addition to the active ingredients;

[0025] Further, the auxiliary ingredients include one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreezing agents, defoaming agents, solvents, stabilizers, film-forming agents, warning colors, penetrants, and carriers;

[0026] Further, the wetting agent is selected from one or more of sodium dodecylbenzene sulfonate, sodium dodecylbenzenesulfonate, saponin powder, alkyl sulfates, Nekal BX, silkworm excrement, alkylphenol polyoxyethylene ether, fatty alcohol polyoxyethylene ether, alkanolamide polyoxyethylene ether and its phosphate or sulfate salt, alkyl polyoxyethylene ether sulfosuccinate;

[0027] Further, the dispersant is selected from one or more of polycarboxylates, lignosulfonates, naphthalene or alkylnaphthalene formaldehyde condensate sulfonates, calcium alkylbenzenesulfonate, alkylphenol polyoxyethylene phosphate, fatty alcohol polyoxyethylene polyoxypropylene ether, fatty alcohol polyoxypropylene polyoxypropylene ether, and polymeric alkylaryl sulfonates;

[0028] Further, the emulsifier is selected from one or more of fatty alcohol polyoxyethylene ether, fatty alcohol ethylene oxide - propylene oxide copolymer, phenethylphenol polyoxyethylene polyoxypropylene ether, alkylphenol polyoxyethylene ether, fatty amine polyoxyethylene ether, alkylbenzene sulfonate, styrylphenol polyoxyethylene ether, and fatty acid polyoxyethylene ester;

[0029] Further, the thickener is selected from one or more of xanthan gum, polyvinyl alcohol, organic bentonite, magnesium aluminum silicate, and carboxymethyl cellulose;

[0030] Further, the disintegrant is selected from one or more of aluminum chloride, bentonite, sucrose, modified starch, cellulose, urea, sodium carbonate, sodium bicarbonate, sodium chloride, sodium sulfate, citric acid, and tartaric acid;

[0031] Further, the antifreeze is selected from a mixture composed of one or more of alcohols, alcohol ethers, and inorganic salts;

[0032] Further, the defoamer is selected from one or more of silicone oil, C 10 ~C 20 saturated fatty acid compounds, C 8 ~C 10 fatty alcohol compounds, or silicone compounds;

[0033] Further, the solvent is selected from one or more of benzene, toluene, xylene, methanol, ethanol, isopropanol, n-butanol, diesel, N,N-dimethylformamide, cyclohexanone, ethyl acetate, N-methylpyrrolidone, propanol, butanol, ethylene glycol, diethylene glycol, ethylene glycol methyl ether, butyl ether, solvent oil, vegetable oil, vegetable oil derivatives, and deionized water;

[0034] Further, the preservative is selected from one or more of sorbic acid, sodium sorbate, potassium sorbate, benzoic acid, sodium benzoate, sodium p-hydroxybenzoate, and methyl p-hydroxybenzoate;

[0035] Further, the stabilizer is selected from one or more of oxalic acid, succinic acid, adipic acid, borax, and epoxidized vegetable oil;

[0036] Further, the warning color is selected from any one or more of blue, green, red, purple, and yellow and their adjusted colors;

[0037] Further, the film-forming agent is selected from one or more of sodium carboxymethyl starch, sodium carboxymethyl cellulose, sodium alginate, polyvinyl alcohol, and polyacrylic acid;

[0038] Further, the carrier is selected from one or more of kaolin, bentonite, attapulgite, light calcium carbonate, diatomaceous earth, and silica;

[0039] Further, the pesticide composition can be prepared into any preparation dosage form permitted in agriculture, and the preparation dosage form is a solid preparation, a liquid preparation, or a seed treatment preparation;

[0040] Further, the solid preparation is a water-dispersible granule or a wettable powder, and the liquid preparation is an emulsion in water, a suspension concentrate, or an emulsifiable concentrate;

[0041] The present invention also discloses the application of the pesticide composition as described above in controlling pathogenic bacteria of agricultural, forestry, and horticultural plants.

[0042] Further, the plant pathogenic bacterium is Pyricularia oryzae;

[0043] Further, the pesticide composition is applied to the plant pathogenic bacterium and / or its environment in an effective amount.

[0044] The present invention has the following advantages compared with the prior art:

[0045] 1) The pesticide composition or its preparation of the present invention is highly efficient and broad-spectrum, highly effective in preventing diseases, applicable to a wide range of crops, reducing the dosage of pesticides, and lowering the production cost;

[0046] 2) The pesticide composition or its preparation of the present invention shows good control effects on various plant pathogenic bacteria and has a synergistic effect under a certain mass ratio;

[0047] 3) The pesticide composition or its preparation of the present invention can delay the generation of drug resistance in pathogenic bacteria. Detailed implementation manners

[0048] In order to better illustrate the effective control effect of the present invention, the above-mentioned example agents are used to make the technical solutions, purposes, and advantages of the present invention clearer and more understandable. The present invention is described by the following specific examples, but the present invention is not limited to these examples. The technical effect test of the present invention adopts a combination of indoor bioassay and field test.

[0049] Preparation examples:

[0050] Preparation Example 1: 48% Bifemetstrobin·carbendazim wettable powder (12:36)

[0051] Preparation Example 2: 24% Bifemetstrobin·carbendazim suspension concentrate (4:20)

[0052] Preparation Example 3: 44% Bifemetstrobin·thiophanate-methyl wettable powder (4:40)

[0053] Preparation Example 4: 20% Bifemetstrobin·thiophanate-methyl suspension concentrate (3:17)

[0054] Preparation Example 5: 8% Bifemetstrobin·isoprothiolane emulsion in water (1:7)

[0055] Preparation Example 6: 12% Bifemetstrobin·isoprothiolane emulsifiable concentrate (2:10)

[0056] Preparation Example 7: 46% Bifemetstrobin·isoprothiolane wettable powder (6:40)

[0057] Specific formulation composition and preparation method:

[0058] 48% Bifemetstrobin·Carbendazim wettable powder (12:36)

[0059] Formulation composition: 12% Bifemetstrobin, 36% Carbendazim, 1.5% naphthalene sulfonate, 1.5% sodium lignosulfonate, 4% alkyl naphthalene sulfonate, 2.5% Nekal BX, 5% bentonite, 5% white carbon black, kaolin to make up the balance.

[0060] Preparation method: Mix the active ingredients, dispersant, wetting agent and filler according to the formulation ratio, stir evenly in a stirring kettle, and pulverize and mix evenly for multiple times by an air flow pulverizer to obtain the wettable powder of the composition of the present invention.

[0061] 24% Bifemetstrobin·Carbendazim suspension concentrate (4:20)

[0062] Formulation composition: 4% Bifemetstrobin, 20% Carbendazim, 1.5% Guerbet alcohol polyoxyethylene ether, 4% styrylphenol polyoxyethylene ether phosphate, 2% ethylene glycol oxyethylene polyoxypropylene ether, 1% naphthalene sulfonate formaldehyde condensate, 0.25% xanthan gum, 1% magnesium aluminum silicate, 5% glycerol, 0.1% potassium benzoate, 0.5% silicone defoamer, deionized water to make up the balance.

[0063] Preparation method: Place the active ingredient, surfactant and other functional additives into the reaction kettle in sequence, add water and mix evenly, then carry out high-speed shearing and wet grinding, and finally homogenize and filter to obtain the suspension concentrate product.

[0064] 44% Bifemetstrobin·Thiophanate-methyl wettable powder (4:40)

[0065] Formulation composition: 4% Bifemetstrobin, 40% Thiophanate-methyl, 1.5% sodium lignosulfonate, 4% alkyl naphthalene sulfonate, 2.5% Nekal BX, 4% naphthalene sulfonate formaldehyde condensate, 10% white carbon black, 3% starch, kaolin to make up the balance.

[0066] Preparation method: Mix the active ingredients, dispersant, wetting agent and filler according to the formulation ratio, stir evenly in a stirring kettle, and pulverize and mix evenly for multiple times by an air flow pulverizer to obtain the wettable powder product of the composition of the present invention.

[0067] 20% Bifemetstrobin·Thiophanate-methyl suspension concentrate (3:17)

[0068] Formulation composition: 3% Bifemetstrobin, 17% Thiophanate-methyl, 1.5% Guerbet alcohol polyoxyethylene ether, 4% Styrylphenol polyoxyethylene ether phosphate, 2% Ethylene glycol oxyethylene polyoxypropylene ether, 1% Sodium polycarboxylate, 0.25% Xanthan gum, 1% Magnesium aluminum silicate, 5% Glycerol, 0.1% Potassium benzoate, 0.5% Organosilicon defoamer, deionized water to make up the balance;

[0069] Preparation method: Place the active ingredients, surfactants and other functional auxiliaries in a reaction kettle in sequence, add water and mix evenly, carry out high-speed shearing, wet grinding, and finally homogenize and filter to obtain the suspension agent product.

[0070] 8% Bifemetstrobin·Isoprothiolane emulsion in water (1:7)

[0071] Formulation composition: 1% Bifemetstrobin, 7% Isoprothiolane, 4% Xylene, 10% Cyclohexanone, 1.2% BHT, 2% Castor oil polyoxyethylene ether phosphate, 5% Ethylene oxide-propylene oxide copolymer, 5% Glycerol, 0.1% Silicone oil, 0.1% Xanthan gum, 0.1% Sodium benzoate, deionized water to make up the balance;

[0072] Preparation method: Mix the surfactant, antifreeze and water to form an aqueous phase, then dissolve the active ingredients with a solvent and add them to the aqueous phase under stirring. After stirring evenly, shear to a particle size D 90 ≤5μm, add a thickening agent and a preservative and continue to shear for 10 min, then add a defoamer and stir evenly to form an O / W type emulsion in water product.

[0073] 12% Bifemetstrobin·Isoprothiolane emulsifiable concentrate (2:10)

[0074] Formulation composition: 2% Bifemetstrobin, 10% Isoprothiolane, 15% EO / PO block copolymer, 2% Castor oil polyoxyethylene ether, 15% Acetophenone, 12% Propylene glycol methyl ether, 2% Calcium dodecylbenzenesulfonate, Xylene to make up the balance;

[0075] Preparation method: Add the metered active ingredients, solvents and cosolvents to a blending kettle and stir to dissolve them, then add an emulsifier, make up the balance with the remaining solvent, stir evenly in a stirring kettle, and filter to obtain the emulsifiable concentrate product required by the present invention.

[0076] 46% Bifemetstrobin·Isoprothiolane wettable powder (6:40)

[0077] Formulation composition: 6% Bifemetstrobin, 40% Isoprothiolane, 1% Naphthalene sulfonate, 1.5% Sodium lignosulfonate, 4% Alkylnaphthalene sulfonate, 2.5% Nekal BX, 4% Naphthalene sulfonate formaldehyde condensate, 5% Kaolin, 8% Silica white, and the balance is made up with kaolin;

[0078] Preparation method: Mix the active ingredients, dispersant, wetting agent and filler according to the formulation ratio, stir evenly in a stirring kettle, and perform multiple pulverizations and mix evenly with an air flow pulverizer to obtain the wettable powder product of the composition of the present invention.

[0079] Indoor activity test

[0080] Example 1: Indoor combined effect test on rice blast

[0081] Test basis:

[0082] "Pesticide indoor bioassay test guidelines" Part 2 of fungicides: Petri dish method for inhibiting the mycelial growth of pathogenic fungi NY / T 1156.2 - 2006;

[0083] "Pesticide indoor bioassay test guidelines" Part 6 of fungicides: Determination of combined effects of mixtures NY / T 1156.6 - 2006;

[0084] Test target: Pyricularia oryzae Cav.

[0085] Test agents: 95% Bifemetstrobin technical, 92% Carbendazim technical, 97% Thiophanate-methyl technical, 95% Isoprothiolane technical; the above technicals are all provided by the group R & D center.

[0086] Agent preparation: Dissolve the above test agents with a suitable solvent, and then dilute with 0.1% Tween-80 aqueous solution, and set the required series of mass concentrations according to the activity of the agents.

[0087] Test method: Under sterile conditions, add to the melted PDA medium in a certain proportion, mix and pour into a sterilized petri dish to make a series of concentration gradient medicated medium plates. First, culture the tested Pyricularia oryzae strains on the PDA medium at 25°C for 7 - 10 days. When the colony grows to the edge of the petri dish, use a sterilized punch to punch out a mycelial cake at the edge of the colony, and then transfer the mycelial cake to the center of the above medicated medium plate. Use the non-medicated plate medium as a control.

[0088] Test treatment: One mycelial cake is inoculated on each plate, and each treatment is repeated 4 times.

[0089] Investigation method: Place the inoculated Petri dishes in a biochemical incubator and culture them at (25 ± 1) °C. Investigate the mycelial growth of the pathogenic bacteria according to the mycelial growth in the blank control Petri dishes. Measure the colony diameter of each colony with a caliper, with the unit being millimeters (mm). Measure the diameter of each colony vertically once using the cross method and take the average value.

[0090] Data statistics and calculation method: According to the investigation results, calculate the mycelial growth inhibition rate of each treatment concentration on the tested target bacteria using the following formula. Based on the logarithmic values of each drug concentration and the corresponding inhibition probability values, conduct analysis using a statistical analysis system to obtain the virulence regression equation, EC 50 value and correlation coefficient, and evaluate the activity of the tested drugs on the biological test materials.

[0091]

[0092] Where:

[0093] I—the inhibition rate of colony growth;

[0094] D 0 —the growth diameter of the blank control colony;

[0095] D t —the growth diameter of the colony treated with the drug.

[0096] Calculate the co-toxicity coefficient (CTC) of the mixture according to Sun Yunpei's method and evaluate the type of joint action.

[0097] CTC ≥ 120 indicates a synergistic effect, CTC ≤ 80 indicates an antagonistic effect, and CTC between 80 and 120 indicates an additive effect.

[0098] The co-toxicity coefficient (CTC value) of the mixture is calculated as follows:

[0099]

[0100] Where:

[0101] ATI—the measured virulence index of the mixture;

[0102] S—the EC 50 , with the unit of milligrams per liter (mg / L);

[0103] M—the EC 50 , with the unit of milligrams per liter (mg / L).

[0104] TTI = TI A *P A +TI B *P B

[0105] Where:

[0106] TTI - Theoretical toxicity index of the mixture

[0107] TI A - Toxicity index of agent A

[0108] P A - Percentage content of agent A in the mixture, in percentage (%)

[0109] TI B - Toxicity index of agent B

[0110] P B - Percentage content of agent B in the mixture, in percentage (%).

[0111]

[0112] In the formula:

[0113] CTC - Co - toxicity coefficient

[0114] ATI - Measured toxicity index of the mixture

[0115] TTI - Theoretical toxicity index of the mixture

[0116] Indoor test results:

[0117] As shown in the results of Table 1, each test agent showed good antibacterial effects against the rice blast pathogen. Among them, when the mass ratio of Bifemetstrobin to carbendazim was in the range of 1:60 - 42:1, the co - toxicity coefficients were all greater than 80, and the combined effects were all additive or synergistic; when the mass ratio of Bifemetstrobin to carbendazim was in the range of 1:60 - 22:1, the co - toxicity coefficients were all greater than 120, and the synergistic effect was significant; when the mass ratio of Bifemetstrobin to carbendazim was 1:3, its co - toxicity coefficient was the largest at 213.588.

[0118] Table 1 Results of indoor combined action test of Bifemetstrobin and carbendazim against rice blast

[0119]

[0120] As shown in the results of Table 2, when the mass ratio of Bifemetstrobin to Thiophanate-methyl is in the range of 1:42 to 28:1, the co-toxicity coefficient is greater than 120, and the combined effect shows synergism; when the mass ratio of Bifemetstrobin to Thiophanate-methyl is in the range of 1:28 to 28:1, the co-toxicity coefficient is greater than 130, and the synergistic effect is significant; when the mass ratio of Bifemetstrobin to Thiophanate-methyl is 1:10, the co-toxicity coefficient is the largest, which is 224.306.

[0121] Table 2 Results of Indoor Combined Action Test of Bifemetstrobin and Thiophanate-methyl against Rice Blast

[0122]

[0123]

[0124] As shown in the results of Table 3, when the mass ratio of Bifemetstrobin to Isoprothiolane is in the range of 1:42 to 30:1, the co-toxicity coefficient is greater than 120, and the combined effect shows synergism; when the mass ratio of Bifemetstrobin to Isoprothiolane is in the range of 1:42 to 20:1, the co-toxicity coefficient is greater than 140, and the synergistic effect is significant; when the mass ratio of Bifemetstrobin to Isoprothiolane is 1:7, the co-toxicity coefficient is the largest, which is 275.181.

[0125] Table 3 Results of Indoor Combined Action Test of Bifemetstrobin and Isoprothiolane against Rice Blast

[0126]

[0127] Example 2: Field Efficacy Test of Rice Blast

[0128] Test Basis: The test refers to GB / T 17980.19 - 2000 "Guidelines for Field Efficacy Trials (Part 1) Fungicides for Controlling Leaf Diseases of Rice".

[0129] Test Site: The test was carried out in the rice test field of Tianli Village, Daowai District, Harbin City, Heilongjiang Province. The test site is flat, with uniform fertility, and the soil is albic soil. The crop varieties, planting periods, growth vigors, fertilizer and water management conditions of each test plot are basically the same.

[0130] Test Agents and Dosages:

[0131] Table 4 Test Agents and Dosages

[0132]

[0133]

[0134] Experimental design: The experimental design has 8 treatments, each treatment is repeated 4 times, and clean water is used as a blank control. The area of ​​the plot is 60m 2 , each plot is randomly arranged in blocks, and protection rows are set up in adjacent plots.

[0135] Time and frequency of application: The test was conducted by applying pesticide once at the early stage of rice rupture (rupture rate 5% to 10%), with a water consumption of 30L per mu and a 3WBD-16L electric sprayer for uniform spraying.

[0136] Experimental field conditions: No other fungicides were used in each area before and during the experiment, and the management level of each area was consistent.

[0137] Survey method: Five sampling points are adopted in each plot, with 50 ears at each point, and a total of 250 ears are surveyed in each plot, for one survey in total. Before the rice matures and is harvested, the number of diseased ears at all levels in each plot is surveyed, and the disease index and control effect are calculated.

[0138] Safety investigation of pesticides: During the test, rice grew normally, and the pesticides in the tested concentrations did not cause any damage to rice plants or other non-target organisms.

[0139] The classification records are made according to the following classification method:

[0140] Level 0: no disease;

[0141] Level 1: less than 5% loss per ear (individual branches and stalks are diseased);

[0142] Level 3: 6% to 20% loss per ear (about one-third of the branches and stalks are diseased);

[0143] Level 5: 21% to 50% loss per ear (the neck or main axis of the ear is diseased, and the grains are half-shrunken);

[0144] Level 7: 51% to 70% loss per ear (the neck of the ear is diseased and most of the grains are shrunken);

[0145] Level 9: 71% to 100% loss per ear (the ear neck becomes diseased, resulting in white ears).

[0146] The efficacy is calculated according to the following formula:

[0147]

[0148] The results of the field efficacy test are shown in the following table:

[0149] From the analysis of the field efficacy test results in Table 5, it can be seen that the compounding of Bifemetstrobin with carbendazim, thiophanate-methyl, and isoprothiolane has good control effects on rice blast. Before the rice was matured and harvested after the application of the pesticides, an investigation on rice panicle blast was carried out. The control effects of 24% Bifemetstrobin·carbendazim suspension concentrate (4:20), 20% Bifemetstrobin·thiophanate-methyl suspension concentrate (3:17), and 12% Bifemetstrobin·isoprothiolane emulsifiable concentrate (2:10) were 87.05%, 86.59%, and 88.02% respectively.

[0150] Table 5 Field efficacy test results of each test pesticide on rice blast

[0151]

[0152] In summary, through indoor toxicity determination and field efficacy tests, it can be seen that the pesticide composition obtained by compounding Bifemetstrobin of the present invention with carbendazim, thiophanate-methyl, and isoprothiolane has good control effects on rice blast, is safe for rice, has significant control effects, is superior to single agents in terms of delaying the generation of drug resistance and prolonging the persistence period, can effectively reduce costs, and reduce pesticide residues.

[0153] Although the present application has described specific embodiments in detail with the help of examples, the disclosure of the present application can be in various modified and alternative forms. However, it should be understood that the disclosure of the present application is not limited to the specific forms disclosed. On the contrary, the disclosure of the present application covers all modifications, equivalents, and alternative forms within the scope of the disclosure of the present application, and the scope of the present application is defined by the appended claims and their legal equivalents.

Claims

1. A pesticide composition, characterized in that: The pesticide composition comprises an active ingredient A and an active ingredient B, wherein the active ingredient A is Bifemetstrobin, and the active ingredient B is any one of carbendazim, methyl thiophanate and rice blast.

2. The pesticide composition according to claim 1, characterized in that The mass ratio of the active ingredient A to the active ingredient B is 1:60 to 42:

1.

3. The pesticide composition according to claim 1, characterized in that The active ingredient B is carbendazim, and the mass ratio of Bifemetstrobin to carbendazim is 1:60 to 22:1; The active ingredient B is methyl thiophanate, and the mass ratio of Bifemetstrobin to methyl thiophanate is 1:42 to 28:1; The active ingredient B is Bifemetstrobin, and the mass ratio of Bifemetstrobin to Bifemetstrobin is 1:42 to 30:

1.

4. The pesticide composition according to claim 1, characterized in that The active ingredient B is carbendazim, and the mass ratio of Bifemetstrobin to carbendazim is 1:46 to 22:1; The active ingredient B is methyl thiophanate, and the mass ratio of Bifemetstrobin to methyl thiophanate is 1:28 to 28:1; The active ingredient B is Bifemetstrobin, and the mass ratio of Bifemetstrobin to Bifemetstrobin is 1:42 to 20:

1.

5. The pesticide composition according to claim 1, characterized in that The total weight of the pesticide composition is 100 wt%, and the sum of the content of the active ingredient A and the active ingredient B in the pesticide composition is 1 to 80 wt%; Preferably, the total content of the active ingredient A and the active ingredient B in the pesticide composition is 5 to 70 wt %.

6. The pesticide composition according to claim 5, characterized in that The pesticide composition includes auxiliary ingredients in addition to active ingredients, and the auxiliary ingredients include one or more of wetting agents, dispersants, emulsifiers, thickeners, disintegrants, antifreeze agents, defoamers, solvents, stabilizers, film formers, warning colors, penetrants and carriers.

7. The pesticide composition according to claim 1, characterized in that The pesticide composition can be prepared into any formulation form permitted in agriculture, and the formulation form is a solid formulation, a liquid formulation or a seed treatment formulation; the solid formulation is a water-dispersible granule or a wettable powder, and the liquid formulation is an aqueous emulsion, a suspension, or an emulsifiable concentrate.

8. Use of the pesticide composition according to any one of claims 1 to 7 in preventing and controlling pathogenic bacteria in agriculture, forestry or horticulture.

9. The use according to claim 8, characterized in that The plant pathogenic bacteria is rice blast fungus.

10. The use according to claim 8, characterized in that The pesticide composition is applied to the plant pathogenic bacteria and / or its environment in an effective amount.

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