Plant fungicide

Abstract

The invention provides a plant fungicide. The plant fungicide comprises the following components in percentage by weight: 0.3-3% of a centella asiatica extracting solution; 0.3-3% of a Chinese herbaceous peony extracting solution; 0.3-3% of a radix scutellariae extracting solution; 0.3-3% of an artemisia apiacea extract; 0.05 to 0.5 percent of a cationic surface active agent; 0.3 to 5.0 percent of an ampholytic surfactant; 82.5% to 98.45% of water; according to the plant bactericide provided by the invention, the bactericidal effects of the centella asiatica extracting solution, the Chinese herbaceous peony extracting solution, the scutellaria baicalensis extracting solution and the artemisia apiacea extracting solution are utilized, and meanwhile, the characteristics of mild performance, rich foam and strong washing ability of the cationic surfactant and the ampholytic surfactant are utilized; long-acting killing of viruses such as escherichia coli, staphylococcus aureus, candida albicans and staphylococcus albus is achieved, and the safe and long-acting sterilization effect is achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of plant fungicides, and in particular, to a plant fungicide. Background Art

[0002] Fungicides are currently widely used in people's daily lives, and there are endless common fungicides. For example, ethanol with a concentration of 75% and chlorine dioxide belong to common disinfectants. However, ethanol with a concentration of 75% cannot kill some viruses, is flammable and explosive. At the same time, ethanol is volatile and will evaporate completely in a short time after coating, and cannot continuously sterilize.

[0003] 84 disinfectant, chlorine dioxide, etc. all have good disinfection effects, but their strong pungent smell and corrosive oxidation are very inconvenient in use; chlorine dioxide fungicide is very unstable in aqueous solution and is sensitive to light. Conventional chlorine dioxide disinfectant or disinfection tablet solution will quickly disappear when coated on items, and cannot achieve long-term disinfection and sterilization effects.

[0004] Hydrogen peroxide-based disinfection fungicides also have obvious bactericidal effects, but hydrogen peroxide is unstable and easy to decompose, which is also not ideal in use. Hydrogen peroxide decomposes continuously, and oxygen accumulates significantly in a closed storage container to generate pressure. At a low concentration, the bactericidal rate is poor, and at a high concentration, it has strong corrosiveness to the skin, and there is a certain danger in use. Heavy metal silver, copper, and zinc ions have certain bactericidal effects, but they are only effective at relatively high concentrations. At the same time, heavy metals have certain cumulative and potential hazards to people's bodies.

[0005] Currently, although there are also some plant antibacterial disinfectants, most of them focus on plant extracts such as honeysuckle, mugwort leaf, chinaberry fruit, isatis root, houttuynia cordata, pomegranate peel, etc., and are applied to fields such as laundry detergent, fabrics, air purification, and cosmetics. However, it is found through experiments that myrtle extract, wormwood extract, and rose extract with antibacterial effects become turbid after being dissolved in water, which becomes obvious after three days. Wormwood is lighter and myrtle is the heaviest, and a clear, transparent and stable antibacterial liquid cannot be obtained.

[0006] Therefore, the fungicides in the prior art cannot meet people's requirements for long-term, safe, and stable fungicides. Summary of the Invention

[0007] The main object of the present invention is to provide a plant fungicide to solve the technical problem that the fungicides in the related art cannot meet people's requirements for long-term, safe, and stable fungicides.

[0008] To achieve the above object, according to one aspect of the present invention, there is provided a plant composite long-acting fungicide, which comprises the following components by weight percentage:

[0009] Centella asiatica extract 0.3 - 3%;

[0010] 0.3 - 3% of Paeonia lactiflora extract;

[0011] 0.3 - 3% of Scutellaria baicalensis extract;

[0012] 0.3 - 3% of Artemisia annua extract;

[0013] 0.05 - 0.5% of cationic surfactant;

[0014] 0.3 - 5.0% of amphoteric surfactant;

[0015] 82.5 - 98.45% of water.

[0016] Furthermore, the cationic surfactant is dialkyl (C8 - C18) dimethyl ammonium bromide.

[0017] Furthermore, the amphoteric surfactant is betaine.

[0018] Furthermore, the weight percentage of Centella asiatica extract is 1.5%.

[0019] Furthermore, the weight percentage of Paeonia lactiflora extract is 1.8%.

[0020] Furthermore, the weight percentage of Artemisia annua extract is 1.8%.

[0021] Furthermore, the weight percentage of Scutellaria baicalensis extract is 1.5%.

[0022] Furthermore, the weight percentage of the cationic surfactant is 0.18%.

[0023] Furthermore, the water is deionized water or distilled water.

[0024] Furthermore, the weight percentage of the amphoteric surfactant is 1.5%.

[0025] After long - term research and numerous repeated comparative tests, the above - mentioned long - acting bactericidal and disinfecting product of plant extracts is obtained. Using the plant compound long - acting bactericide of the present invention, the bactericidal effects of Centella asiatica extract, Paeonia lactiflora extract, Scutellaria baicalensis extract, and Artemisia annua extract are utilized.

[0026] The above combination utilizes the mild properties, rich foam, and strong detergency of cationic surfactants and amphoteric surfactants to achieve a disinfection rate of 99.999% against Escherichia coli, Staphylococcus aureus, Candida albicans, Staphylococcus epidermidis; Poliovirus, Human Immunodeficiency Virus (HIV), Murine Norovirus (MNV), SARS-CoV-2 KP2, Adenovirus, Monkeypox Virus (HPVX), Influenza A Virus (H1N1), Influenza B Virus (BV-ca), Enterovirus 71 (EV71), Mycoplasma pneumoniae ATCC15531, Dengue Virus (DENV-2), etc. The long-term test after spraying for seven days can still reach 99.99%, achieving a safe and long-lasting bactericidal effect. Detailed implementation manners

[0027] It should be noted that the terms used herein are only for describing the specific implementation manners and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, they indicate the presence of features, steps, operations, devices, components, and / or their combinations.

[0028] Unless otherwise specifically stated, the relative arrangements, numerical expressions, and numerical values of the components and steps described in these embodiments do not limit the scope of the present invention. Technologies, methods, and devices known to those of ordinary skill in the relevant art may not be discussed in detail, but where appropriate, the said technologies, methods, and devices should be regarded as part of the authorized specification. In all the examples shown and discussed here, any specific value should be interpreted as merely exemplary and not as a limitation. Therefore, other examples of the exemplary embodiments may have different values. To solve the technical problem that existing fungicides cannot meet people's requirements for long-lasting, safe, and stable fungicides in the prior art, the present application provides a plant composite long-lasting fungicide.

[0029] The first embodiment of the present application provides a plant composite long-lasting fungicide, which comprises the following components by weight percentage: Centella asiatica extract 0.3 - 3%; Paeonia lactiflora extract 0.3 - 3%; Scutellaria baicalensis extract 0.3 - 3%; Artemisia annua extract 0.3 - 3%; Cationic surfactant 0.05 - 0.5%; Amphoteric surfactant 0.3 - 5.0%; Water 82.5 - 98.45%.

[0030] In the process of applying a single plant extract to epidemic viruses and pathogenic bacteria, although the single plant extract also has an inhibitory effect, we found that the disinfection effect of the single plant extract is limited. The combined use of different plant extracts will achieve a superimposed effect. In this application, through repeated experiments on different plant extracts, it is found that asiatic acid in centella asiatica extract, baicalin in scutellaria baicalensis extract, and gallic acid in paeonia lactiflora extract all contain carboxylic acid groups, and the latter two are also connected with hydroxyl groups, and they have certain anionic properties. The dialkyl (C8-C18) dimethyl ammonium bromide surfactant contains cationic properties, and they will interact with each other to form ionic aggregates to play a synergistic effect when attacking viruses and bacteria. Further, asiatic acid has a structure of five connected six-membered rings, and the first six-membered ring contains three hydroxyl groups. Asiaticoside is connected with three six-membered ether ring structures in the form of organic esters, and each six-membered ring is connected with three hydroxyl groups; Baicalin and wogonoside also contain a trihydroxy six-membered ring structure, and strong hydrogen bonds are easily formed between them, so that they can act jointly against the attack of bacteria and viruses; In addition, the conjugate structure of baicalin and the conjugate structure of flavonoids can both play a conjugate synergistic effect. In this application, the above-mentioned synergistic effects are utilized to achieve a significant killing effect on pathogenic bacteria and viruses.

[0031] Applying the plant composite long-acting bactericide provided by this application, using centella asiatica extract, paeonia lactiflora extract, scutellaria baicalensis extract, and artemisia annua extract, adding a small amount of the cationic surfactant dialkyl (C8-C18) dimethyl ammonium bromide, the amphoteric surfactant betaine with mild performance, rich foam, and strong detergency and pure water are combined to form a long-acting bactericidal and disinfectant. The disinfection rates for Escherichia coli, Staphylococcus aureus, Candida albicans, Staphylococcus epidermidis; Poliovirus, Human immunodeficiency virus HIV, Murine norovirus MNV, Coronavirus disease 2019 KP2, Adenovirus, Monkeypox virus HPVX, Influenza A virus H1N1, Influenza B virus BV-ca, Hand, foot and mouth disease virus EV71, Mycoplasma pneumoniae ATCC15531, Dengue virus DENV-2, etc. reach 99.999%, and the long-term test after spraying for seven days can still reach 99.99%, which can achieve a safe and long-acting bactericidal effect.

[0032] Further, the cationic surfactant is dialkyl (C8-C18) dimethyl ammonium bromide. By adding the cationic surfactant, the mixture can be made uniform and stable, and has good dispersion function, and can be evenly coated on the skin and the surface of objects naturally; At the same time, dialkyl (C8-C18) dimethyl ammonium bromide also has a bactericidal effect, and is not easy to volatilize, and has a long retention time, and can achieve a long-acting bactericidal effect. Preferably, the weight percentage of dialkyl (C8-C18) dimethyl ammonium bromide is 0.18%.

[0033] For easy cleaning, betaine is used as an amphoteric surfactant in the plant composite long-acting bactericide provided by this application. Betaine is both a cationic surfactant and anionic surfactant, with mild properties, friendly to the skin, non-irritating, rich in foam, strong in washing ability, and good in cleaning effect. Preferably, the weight percentage of the betaine is 1.5%; the betaine described in this application can be commercially available betaine.

[0034] In another specific embodiment of this application, the composition of the asiatic pennywort extract contains madecassic acid, asiaticoside, and centelloside, which have significant antibacterial effects, especially good at inhibiting Staphylococcus aureus, Pseudomonas aeruginosa, Propionibacterium acne, and various dysentery bacilli. At the same time, it has skin care effects such as nourishing and moisturizing the skin, firming and anti-wrinkle, and beautifying and whitening. Preferably, the weight percentage of the asiatic pennywort extract is 1.5%. The asiatic pennywort extract described in this application can be commercially available asiatic pennywort extract.

[0035] Furthermore, the peony extract contains paeoniflorin, albiflorin, benzoylpaeoniflorin, and also contains gallic acid, etc., which has obvious inhibitory effects on some bacteria and fungi, and at the same time has the functions of skin whitening and moisturizing and nourishing the skin. Preferably, the usage amount of the peony extract is 1.8%; the peony extract described in this application can be commercially available peony extract.

[0036] The skullcap extract contains baicalein, baicalin, wogonoside, and baicalein new, which has antibacterial effects and obvious inhibitory effects on Gram-positive bacteria, Gram-negative bacteria, and pathogenic skin fungi. At the same time, this extract has strong ultraviolet absorption ability and can inhibit dermatitis, and is an excellent natural skin sunscreen extract. Preferably, the usage amount of the skullcap extract is 1.5%; the skullcap extract described in this application can be commercially available skullcap extract.

[0037] The artemisia annua extract contains volatile oil components such as β-pinene, α-pinene, germacrene D, 1,8-cineole, etc., and also contains flavonoids, dihydroflavonoids, coumarins, sesquiterpenes, diterpenoids. The antibacterial and anti-inflammatory components have very strong inhibitory effects on Staphylococcus and Catarrhal coccus, and have an inhibitory effect on Pseudomonas aeruginosa. The artemisia annua volatile oil has an antibacterial effect on all dermatophytes at a concentration of 0.25%, and can sterilize all dermatophytes at a concentration of 1%; preferably, the usage amount of the artemisia annua extract is 1.8%; the artemisia annua extract described in this application can be commercially available artemisia annua extract.

[0038] To ensure the disinfection effect, the water described in this application is high-purity water with a conductivity less than 5×10 -6 Ω.cm -1 Preferably, the water can be deionized water or distilled water, which is beneficial to further ensure the disinfection and sterilization effect.

[0039] The disinfection effects of disinfectants with different component ratios are verified and described as follows:

[0040] Example 1

[0041] The ratio of the natural plant long-acting bactericidal disinfectant (by weight percentage) is:

[0042]

[0043] After mixing for 5 minutes, according to the National Disinfection Technical Specification (2002 version), the suspension method was used for testing. Taking the average value of three tests, the killing rate of Staphylococcus aureus reached 99.30%, and the cleaning effect was good.

[0044] Example 2

[0045] The ratio of the natural plant long-acting bactericidal disinfectant (by weight percentage) is:

[0046]

[0047] After mixing for 5 minutes, according to the National Disinfection Technical Specification (2002 version), the suspension method was used for testing. The average value was taken, and the killing rate of Staphylococcus aureus reached 99.47%, and the cleaning effect was relatively good.

[0048] Example 3

[0049] The ratio of the natural plant long-acting bactericidal disinfectant (by weight percentage) is:

[0050]

[0051] After mixing for 5 minutes, according to the National Disinfection Technical Specification (2002 version), the suspension method was used for testing. The average value of three tests was taken, and the killing rate of Staphylococcus aureus reached 99.90%. The foam was rich and the cleaning effect was good.

[0052] Example 4

[0053] The ratio of the natural plant long-acting bactericidal disinfectant (by weight percentage) is:

[0054]

[0055] After mixing for 5 minutes, according to the National Disinfection Technical Specification (2002 version), the suspension method was used for testing. The average value of three tests was taken, and the killing rate of Staphylococcus aureus reached 99.99%. The cleaning effect was poor.

[0056] Example 5

[0057] The ratio of the natural plant long-acting bactericidal disinfectant (by weight percentage) is:

[0058]

[0059]

[0060] Mix for 5 minutes. Test by the suspension method according to the National Disinfection Technical Specification (2002 Edition). The average value of three tests shows that the killing rate of Staphylococcus aureus reaches 99.999%. The cleaning effect is very good.

[0061] Example Six

[0062] The formulation ratio (by weight percentage) of the natural plant long - acting bactericidal disinfectant is:

[0063]

[0064] Mix for 5 minutes. Test by the suspension method according to the National Disinfection Technical Specification (2002 Edition). The average value of three tests shows that the killing rate of Staphylococcus aureus reaches 99.98%. The cleaning effect is good.

[0065] Example Seven

[0066] The formulation ratio (by weight percentage) of the natural plant long - acting bactericidal disinfectant is:

[0067]

[0068]

[0069] Mix for 5 minutes. Test by the suspension method according to the National Disinfection Technical Specification (2002 Edition). The average value of three tests shows that the killing rate of Staphylococcus aureus reaches 99.999%. The cleaning effect is average.

[0070] Example Eight

[0071] The formulation ratio (by weight percentage) of the natural plant long - acting bactericidal disinfectant is:

[0072]

[0073] Mix for 5 minutes. Test by the suspension method according to the National Disinfection Technical Specification (2002 Edition). The average value of three tests shows that the killing rate of Staphylococcus aureus reaches 99.999%. The cleaning effect is very good. Coat the surface of the object. After three days of testing, the bactericidal rate still reaches 99.999%. After seven days, the bactericidal rate is 99.99%, achieving a long - acting bactericidal effect.

[0074] It can be seen from the above examples that the plant bactericide provided by this application can achieve long - acting bactericidal effect on Staphylococcus aureus; and with the action of surfactants and quaternary ammonium salts, it can achieve a good cleaning effect.

[0075] During the use of the disinfectant provided by this application, it is applicable to disinfection and sterilization in a variety of different scenarios. For example, it is applicable to air, objects, and the human body. The applicable places include hospitals, schools, canteens, offices, airports, stations, etc., and it is also applicable to the disinfection and cleaning of pets.

[0076] During the use process, for the surface of objects or fabrics, wiping, spraying and other methods can be adopted, and the action time is greater than 2 minutes; for tableware, soaking and other methods can be adopted, and the action time is greater than 10 minutes; for the skin and hands, wiping and other methods can be adopted, and the action time is greater than 1 minute; for indoor air, atomization and other methods can be adopted. After atomizing the liquid medicine through equipment such as an atomizer or a humidifier and spraying it into the indoor air, a concentration of 10 ml / m 3 is achieved, and the standard of qualified disinfection can be reached after acting for 1 hour.

[0077] In addition, it should be noted that using words such as "first" and "second" to limit components is only for the convenience of distinguishing the corresponding components. Without additional statements, the above words have no special meanings, so it cannot be understood as a limitation on the protection scope of the present invention.

[0078] The above are only the preferred embodiments of the present invention and are not used to limit the present invention. For those skilled in the art, the present invention can have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A botanical fungicide, characterized in that: The following components are included in weight percentage: Centella asiatica extract 0.3-3%; Peony extract 0.3-3%; Scutellaria baicalensis extract 0.3-3%; Artemisia annua extract 0.3-3%; Cationic surfactant 0.05-0.5%; Amphoteric surfactant 0.3-5.0%; Water 82.5-98.45%.

2. The botanical fungicide according to claim 1, characterized in that The cationic surfactant is dialkyl (C8-C18) dimethyl ammonium bromide.

3. The botanical fungicide according to claim 1, characterized in that The amphoteric surfactant is betaine.

4. The botanical fungicide according to claim 1, characterized in that The weight percentage of the Centella asiatica extract is 1.5%.

5. The botanical fungicide according to claim 1, characterized in that The weight percentage of the peony extract is 1.8%.

6. The botanical fungicide according to claim 1, characterized in that The weight percentage of the Artemisia annua extract is 1.8%.

7. The botanical fungicide according to claim 1, characterized in that The weight percentage of the scutellaria baicalensis extract is 1.5%.

8. The botanical fungicide according to claim 1, characterized in that The weight percentage of the cationic surfactant is 0.18%.

9. The botanical fungicide according to claim 1, characterized in that The water is deionized water or distilled water.

10. The botanical fungicide according to claim 1, characterized in that The weight percentage of the amphoteric surfactant is 1.5%.

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