Traditional Chinese medicine composition for treating lumbar disc herniation and shoulder, neck, waist and leg pain and preparation method

Abstract

The invention relates to a traditional Chinese medicine composition for treating lumbar disc herniation and shoulder, neck, waist and leg pain and a preparation method thereof. The traditional Chinese medicine composition is prepared from rheum officinale, radix cynanchi auriculati, radix pseudostellariae, radix saposhnikoviae, angelica sinensis, folium mori, rhizoma curculiginis, peach kernels, hairyvein agrimony, radix cynanchi paniculati, herba epimedii, olibanum, fishing rod, safflower carthamus, rhizoma cibotii, herba pteridis multifidae, myrrh, radix cyathulae, radix angelicae and lumbricus. The raw materials are cut into sections, broken, crushed or extracted to prepare an ointment, a cream, an emplastrum, a patch, a plaster, a gel, a medicinal liquor, a tincture, an aerosol, a spray and a film agent. The traditional Chinese medicine composition does not contain toxic components and is harmless to a human body. Repeated clinical tests prove that the traditional Chinese medicine composition has a remarkable curative effect on diseases such as lumbar disc herniation, scapulohumeral periarthritis, cervical spondylosis, lumbar muscle degeneration, hyperostosis, rheumatoid arthritis and tennis elbow.

Description

Technical Field

[0001] The present invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating lumbar disc herniation and pain in the shoulders, neck and waist, and a preparation method thereof. Background Art

[0002] Lumbar disc herniation and pain in the shoulders, neck and waist belong to the categories of "injury of tendons", "painful impediment" and "bone impediment" in traditional Chinese medicine. Internal and external factors are the two main causes. The internal factors include old age and weakness, tissue degeneration, and damaged meridians after trauma, resulting in qi stagnation and blood stasis, swelling and pain. The external factors are the invasion of wind, cold and damp pathogens, blocking the meridians. Due to long-term fatigue, if middle-aged and elderly people overwork for a long time and use force unevenly, it will damage the limb muscles, fascia, ligaments and joints, and then be infected with wind, cold and damp pathogens, resulting in local collateral obstruction, qi stagnation and blood stasis, and pain due to blockage.

[0003] Common diseases of lumbar disc herniation and pain in the shoulders, neck and waist include: lumbar disc herniation, scapulohumeral periarthritis, cervical spondylosis, lumbar muscle strain, bone hyperplasia, arthritis and other diseases. During the illness, due to symptoms such as pain and discomfort, it seriously affects the patient's work and quality of life.

[0004] At present, the treatment of these diseases mainly has two types: non-surgical therapy and surgical therapy. Non-surgical therapy mainly uses acupuncture, massage, physical therapy, traction, block therapy, oral administration of steroidal anti-inflammatory drugs, etc. Surgical therapy is carried out based on the principle of relieving compression, eliminating irritation, enhancing stability and preventing progressive damage. However, there are more complications and contraindications in surgical therapy, and it is only selected when other therapies are ineffective due to high risk, great pain and high cost. In non-surgical therapy, mainly by taking a large amount of antibiotics and western medicines of hormones for a long time, which will cause a series of side effects, such as gastrointestinal dysfunction, nervous system disorders, etc., and the treatment cost is high, the curative effect is not obvious, and it is easy to relapse.

[0005] Existing drugs for treating lumbar disc herniation and pain in the shoulders, neck and waist, such as "An important warming patch for improving pain in the shoulders, neck and waist and its preparation process" with Chinese invention patent number 201410463288.6, contains ingredients such as raw Radix Aconiti Kusnezoffii, raw Radix Aconiti Carmichaeli and Strychnos nux-vomica, and has great toxic and side effects. The Chinese invention patent "A traditional Chinese medicine plaster for treating pain in the shoulders, neck and waist" not only contains ingredients such as raw Radix Aconiti Kusnezoffii and raw Radix Aconiti Carmichaeli, but also contains Manis pentadactyla. Manis pentadactyla is a second-class protected animal in China, and the raw materials are scarce and expensive.

[0006] Therefore, it is imperative to find a safe, effective and economical traditional Chinese medicine for treating lumbar disc herniation and pain in the shoulders, neck and waist. Summary of the Invention

[0007] The technical problem to be solved by the present invention is to provide a traditional Chinese medicine composition for treating lumbar disc herniation and pain in the shoulders, neck and waist.

[0008] Another technical problem to be solved by the present invention is to provide a method for preparing a traditional Chinese medicine composition for treating lumbar disc herniation and pain in the shoulder, neck, waist and legs.

[0009] The traditional Chinese medicine composition of the present invention is composed of raw materials in the following parts by weight:

[0010] 14-108 parts of Rheum officinale, 14-105 parts of Clerodendrum oldhamii, 15-115 parts of Selaginella braunii, 12-109 parts of Saposhnikovia divaricata, 10-99 parts of Angelica sinensis, 10-99 parts of Morus alba, 14-108 parts of Curculigo orchioides, 14-105 parts of Prunus persica, 12-109 parts of Agrimonia pilosa, 13-97 parts of Cynanchum paniculatum, 10-99 parts of Epimedium brevicornu, 16-110 parts of Olibanum, 15-115 parts of Microstegium vimineum, 14-99 parts of Carthamus tinctorius, 20-112 parts of Cibotium barometz, 16-110 parts of Pteris multifida, 15-115 parts of Myrrha, 10-99 parts of Cyathula officinalis, 20-112 parts of Angelica dahurica, 13-97 parts of Pheretima aspergillum.

[0011] The preferred raw material composition of the traditional Chinese medicine composition of the present invention is:

[0012] 35-96 parts of Rheum officinale, 28-90 parts of Clerodendrum oldhamii, 33-77 parts of Selaginella braunii, 35-85 parts of Saposhnikovia divaricata, 35-96 parts of Angelica sinensis, 33-77 parts of Morus alba, 35-95 parts of Curculigo orchioides, 28-90 parts of Prunus persica, 33-77 parts of Agrimonia pilosa, 40-96 parts of Cynanchum paniculatum, 32-92 parts of Epimedium brevicornu, 35-95 parts of Olibanum, 35-85 parts of Microstegium vimineum, 32-92 parts of Carthamus tinctorius, 35-96 parts of Cibotium barometz, 33-77 parts of Pteris multifida, 32-92 parts of Myrrha, 35-96 parts of Cyathula officinalis, 35-95 parts of Angelica dahurica, 28-90 parts of Pheretima aspergillum.

[0013] The preferred raw material composition of the traditional Chinese medicine composition of the present invention is:

[0014] 70 parts of Rheum officinale, 70 parts of Clerodendrum oldhamii, 70 parts of Selaginella braunii, 70 parts of Saposhnikovia divaricata, 70 parts of Angelica sinensis, 70 parts of Morus alba, 70 parts of Curculigo orchioides, 70 parts of Prunus persica, 70 parts of Agrimonia pilosa, 70 parts of Cynanchum paniculatum, 70 parts of Epimedium brevicornu, 70 parts of Olibanum, 70 parts of Microstegium vimineum, 70 parts of Carthamus tinctorius, 70 parts of Cibotium barometz, 70 parts of Pteris multifida, 70 parts of Myrrha, 70 parts of Cyathula officinalis, 70 parts of Angelica dahurica, 70 parts of Pheretima aspergillum.

[0015] The preferred raw material composition of the traditional Chinese medicine composition of the present invention is:

[0016] 45 parts of Rheum officinale, 45 parts of Clerodendrum oldhamii, 45 parts of Selaginella braunii, 90 parts of Saposhnikovia divaricata, 45 parts of Angelica sinensis, 45 parts of Morus alba, 45 parts of Curculigo orchioides, 45 parts of Prunus persica, 45 parts of Agrimonia pilosa, 45 parts of Cynanchum paniculatum, 45 parts of Epimedium brevicornu, 90 parts of Olibanum, 45 parts of Microstegium vimineum, 90 parts of Carthamus tinctorius, 45 parts of Cibotium barometz, 45 parts of Pteris multifida, 45 parts of Myrrha, 45 parts of Cyathula officinalis, 90 parts of Angelica dahurica, 45 parts of Pheretima aspergillum.

[0017] The raw material composition of the traditional Chinese medicine composition of the present invention is further preferably as follows:

[0018] 90 parts of Rheum officinale, 49 parts of Clutia root, 49 parts of Ophioglossum pedunculosum, 90 parts of Saposhnikovia divaricata, 49 parts of Angelica sinensis, 49 parts of Morus alba leaf, 49 parts of Curculigo orchioides, 49 parts of Prunus persica, 49 parts of Agrimonia pilosa, 49 parts of Cynanchum paniculatum, 49 parts of Epimedium brevicornu, 49 parts of Olibanum, 49 parts of Microstegium vimineum, 90 parts of Carthamus tinctorius, 90 parts of Cibotium barometz, 49 parts of Pteris multifida, 49 parts of Myrrha, 90 parts of Cyathula officinalis, 90 parts of Angelica dahurica, 49 parts of Pheretima aspergillum.

[0019] The above composition is in weight ratio. Production can be increased or decreased according to the corresponding ratio. For large-scale production, it can be in kilograms or tons. For small-scale production, it can be in milligrams. The weight can be increased or decreased, but the proportion of the raw material weight ratio between the components remains unchanged.

[0020] The single traditional Chinese medicines in the above composition can also be appropriately replaced by traditional Chinese medicines with the same medicinal properties. The drug effect of the replaced traditional Chinese medicine preparation remains unchanged.

[0021] The above weight ratio is obtained through scientific screening. For special patients, such as severe or mild cases, obese or thin patients, the ratio of the composition amount can be adjusted accordingly, increasing or decreasing by no more than 100%, and the drug effect remains unchanged.

[0022] The traditional Chinese medicine composition of the present invention is processed from the traditional Chinese medicine raw materials through the above formula by extraction or other processing methods to make a drug active substance. Subsequently, taking this substance as the raw material, when needed, a pharmaceutically acceptable carrier is added and made according to the conventional pharmaceutical technology. The said active substance can be obtained by decomposing the traditional Chinese medicine raw materials, or can be obtained by other methods, such as: by methods of pulverization, pressing, frying, calcination, grinding, sieving, percolation, extraction, water extraction, alcohol extraction, lipid extraction, ketone extraction, chromatography, etc. These active substances can be substances in the form of extracts, which can be dry extracts or fluid extracts, and different concentrations are made according to different needs of the preparation.

[0023] The weight percentage of the drug active substance of the traditional Chinese medicine composition of the present invention in the preparation can be 0.1 - 99.9%, and the rest is a pharmaceutically acceptable carrier.

[0024] The traditional Chinese medicine preparation of the present invention can be any pharmaceutically acceptable external preparation form, and these forms include: ointments, creams, cataplasms, patches, plasters, gels, medicinal wines, tinctures, aerosols, sprays, films, pastes, powders, powder inhalations, solutions, lotions, liniments. The preparations of the present invention are preferably ointments, cataplasms, creams, patches, plasters, gels.

[0025] The traditional Chinese medicine composition of the present invention may optionally be added with a pharmaceutically acceptable carrier when formulated into a medicament. The pharmaceutically acceptable carrier is selected from: petrolatum, paraffin wax, liquid paraffin, silicone oil, beeswax, lanolin, polyethylene glycol, glycerogelatin, starch glycerin, sodium soap, triethanolamine soaps, polysorbates, fatty alcohol sulfates, sodium lauryl sulfate, calcium soap, monoglyceride, fatty alcohol, rubber, silicone rubber, thermoplastic rubber, rosin, rosin derivatives, zinc oxide, kaolin, polyvinylpyrrolidone, gum arabic, sodium alginate, cellulose and its derivatives, polyacrylic acid and its sodium salt, polyvinyl alcohol, polyvidone, glycerol, colloidal silica, acrylic pressure-sensitive adhesive, hot-melt adhesive, medical hot-melt adhesive, ethylene-vinyl acetate copolymer, water, glycerol propylene glycol, carbomer, tragacanth gum, starch, etc.

[0026] The traditional Chinese medicine composition of the present invention can be made into a far-infrared magnetic therapy patch. Its suitable carriers can be made of hot-melt adhesive, acrylic pressure-sensitive adhesive, rosin, rosin derivatives, petrolatum, lanolin, etc. The infrared functional components can be far-infrared ceramic powder and substances with far-infrared functions available in other fields. The magnetic therapy functional components can be neodymium iron boron permanent magnets, samarium cobalt series permanent magnets, ferrite permanent magnets, rare earth magnetic powder, nano magnetic powder, or substances with magnetic therapy functions available in other fields. Suitable transdermal absorption promoters include azone, dimethyl sulfoxide, menthol, peppermint oil, propylene glycol, eucalyptus oil, camphor, borneol, oleic acid, linoleic acid, etc.

[0027] The traditional Chinese medicine composition of the present invention can be made into a far-infrared magnetic therapy patch. Its beneficial effects are that it can achieve triple effects of medical treatment, heat therapy, and magnetic therapy to achieve the purpose of treating diseases. The principle is: (1) The traditional Chinese medicine composition of the present invention has the effects of relaxing tendons and dredging collaterals, promoting blood circulation to remove blood stasis, dispelling wind and dampness, and reducing swelling and relieving pain through transdermal absorption. (2) Far-infrared has significant resonance and thermal effects, which can dilate capillaries, promote local blood circulation, enhance metabolism between tissues, increase tissue regeneration ability; through neurohumoral reactions, eliminate the pathological process of inflammation, restore the physiological balance state, improve local and systemic disease resistance, activate the function of immune cells, control the development of inflammation and localize it, accelerate the absorption of exudates, and lead to the subsidence of inflammatory edema. (3) A certain magnetic field can enhance the deformability of red blood cells and reduce their aggregation, decrease blood viscosity, dilate blood vessels, accelerate blood flow velocity, improve microcirculation, thereby changing the blood flow state and reducing inflammation and immune responses. In addition, the magnetic field can also play an anti-thrombotic role by reducing the activity of plasma PAI and enhancing the function of the fibrinolytic system.

[0028] The traditional Chinese medicine composition of the present invention can be made into a far-infrared magnetic therapy patch. Through the triple effects of transdermal absorption of traditional Chinese medicine ingredients, resonance effect of far-infrared materials, and magnetic therapy of magnetic materials, it can promote and improve local blood circulation, enhance the metabolism of the pain area, eliminate inflammation, dredge meridians, activate blood circulation to remove stasis, regulate qi and relieve pain. Its therapeutic effect combines physical therapy and drug therapy, is safe and reliable for the human body, and has no toxic side effects. It acts directly on the pain area, has a rapid onset, simple operation, and convenient use.

[0029] The preparation method of the traditional Chinese medicine composition of the present invention is as follows:

[0030] 1. Grind rhubarb, wild sensitive plant, clematis acuminata, divaricate saposhnikovia root, Chinese angelica, mulberry leaf, common curculigo rhizome, peach kernel, hairyvein agrimony, pyrola, epimedium, frankincense, bamboo pole of fishhook, safflower, Chinese goldhair fern rhizome, myrrh, cyathula root, dahurian angelica root, and earthworm into coarse powder, mix evenly, percolate with 50-90% ethanol, and concentrate the percolate into extract, or reflux and extract with 50-90% ethanol for 1-3 times, 0.5-2 hours each time, and concentrate the extract into extract. Make it into hot melt adhesive patch, far-infrared magnetic therapy patch, rubber patch, gel patch, ointment, cream, gel, tincture, aerosol, spray or film.

[0031] 2. Grind rhubarb, wild sensitive plant, clematis acuminata, divaricate saposhnikovia root, Chinese angelica, mulberry leaf, common curculigo rhizome, peach kernel, hairyvein agrimony, pyrola, epimedium, frankincense, bamboo pole of fishhook, safflower, Chinese goldhair fern rhizome, myrrh, cyathula root, dahurian angelica root, and earthworm into coarse powder, mix evenly, percolate with 55-85% ethanol, and concentrate the percolate into extract, or reflux and extract with 55-85% ethanol for 2-3 times, 0.5-1.5 hours each time, and concentrate the extract into extract. Make it into hot melt adhesive patch, far-infrared magnetic therapy patch, rubber patch, gel patch, ointment, cream, gel, tincture, aerosol, spray or film.

[0032] 3. Grind rhubarb, wild sensitive plant, clematis acuminata, divaricate saposhnikovia root, Chinese angelica, mulberry leaf, common curculigo rhizome, peach kernel, hairyvein agrimony, pyrola, epimedium, frankincense, bamboo pole of fishhook, safflower, Chinese goldhair fern rhizome, myrrh, cyathula root, dahurian angelica root, and earthworm into coarse powder, and make it into the medicinal liquor mentioned in pharmacy according to the conventional method.

[0033] 4. Grind rhubarb, wild sensitive plant, clematis acuminata, divaricate saposhnikovia root, Chinese angelica, mulberry leaf, common curculigo rhizome, peach kernel, hairyvein agrimony, pyrola, epimedium, frankincense, bamboo pole of fishhook, safflower, Chinese goldhair fern rhizome, myrrh, cyathula root, dahurian angelica root, and earthworm into fine powder with a particle size of 120-200 μm, or further crush the obtained fine powder into ultrafine powder with a particle size of 0.1-50 μm in an ultrafine pulverization equipment, and make it into hot melt adhesive patch, far-infrared magnetic therapy patch, ointment or cream.

[0034] The pharmacological effects of the traditional Chinese medicine raw materials of the present invention are as follows:

[0035] Rhubarb: Bitter and cold in nature. It acts on the spleen, stomach, large intestine, liver, and pericardium meridians. It purges accumulation, clears heat and purges fire, cools blood and detoxifies, stops bleeding, removes stasis and dredges the meridians, promotes diuresis and reduces jaundice. It is used to treat carbuncles, sores, traumatic injuries, edema, burns and scalds.

[0036] Ixeridium divaricatum: Bitter, pungent, and neutral in flavor. It acts on the heart, lung, liver, bladder, and stomach meridians. It dispels wind and clears heat, activates blood circulation to disperse stasis, and promotes qi flow to relieve pain. It is used to treat wind-heat cough, angina pectoris, stomachache, malaria, dysentery, amenorrhea, leukorrhea, and traumatic injuries.

[0037] Selaginella braunii: Neutral in nature, slightly bitter and astringent in flavor. It acts on the liver, large intestine, and bladder meridians. It clears heat and detoxifies, promotes diuresis and resolves dampness, and calms fright. It is used to treat dysentery, diarrhea, mumps, lymphadenitis, leukorrhea, edema, infantile convulsions, and dog bites.

[0038] Saposhnikovia divaricata: Pungent, sweet, and slightly warm in flavor. It acts on the bladder, liver, and spleen meridians. It dispels wind and relieves the exterior, overcomes dampness and alleviates pain, and stops convulsions. It is used to treat exterior syndrome due to exogenous pathogens, rubella with itching, rheumatic arthralgia, tetanus, and spleen deficiency with excessive dampness.

[0039] Angelica sinensis: Sweet, pungent, and warm in flavor. It acts on the liver, heart, and spleen meridians. It nourishes blood and promotes blood circulation, regulates menstruation and relieves pain, and loosens the bowels. It is used to treat sallow complexion due to blood deficiency, dizziness and palpitation, irregular menstruation, amenorrhea and dysmenorrhea, cold pain in the abdomen, rheumatic arthralgia, traumatic injuries, carbuncles and sores, and constipation due to intestinal dryness.

[0040] Mulberry leaf: Sweet and bitter in flavor, cold in nature. It acts on the lung and liver meridians. It disperses wind-heat, moistens the lung and relieves dryness, suppresses the hyperactive liver-yang, clears the liver and improves eyesight, has anti-inflammatory and swelling-reducing effects, and can lower blood sugar and anticoagulate. It is used to treat wind-heat cold, lung heat, hyperactive liver-yang, and diabetes.

[0041] Curculigo orchioides: Pungent in flavor, hot in nature. It acts on the kidney, liver, and spleen meridians. It tonifies the kidney-yang, strengthens the muscles and bones, and dispels cold-dampness. It is used to treat impotence, spermatorrhea, enuresis caused by insufficient kidney-yang and decline of the vital gate fire, and can also be used to treat soreness and weakness, cold pain in the waist and knees caused by deficiency of the kidney-yang.

[0042] Peach kernel: Bitter and sweet in flavor, neutral in nature. It acts on the heart, liver, and large intestine meridians. It promotes blood circulation to remove stasis, loosens the bowels to relieve constipation, and relieves cough and asthma. It is used to treat amenorrhea and dysmenorrhea, abdominal masses, traumatic injuries; it can also be used to treat lung abscess, intestinal abscess, constipation due to intestinal dryness, and cough and asthma.

[0043] Agrimonia pilosa: Bitter and astringent in flavor, neutral in nature. It acts on the heart, liver, lung, and spleen meridians. It has the effects of astringency, cooling blood, stopping bleeding, tonifying deficiency, detoxifying, arresting malaria, and relieving dysentery. It is mainly used to treat hemoptysis, hematemesis, epistaxis, hematuria, hematochezia, metrorrhagia and metrostaxis, dysentery, diarrhea, physical exhaustion, carbuncles and sores, and itching and leukorrhea in the vulva.

[0044] Cynanchum paniculatum: Pungent in taste; warm in nature. It acts on the liver and stomach meridians. It has pharmacological effects such as promoting blood circulation to dispel wind, relieving pain and reducing swelling, regulating immunity, sedation, analgesia, improving myocardial ischemia, antiviral, anti-inflammatory, and anti-allergic effects. It is mainly used for various pain syndromes such as rheumatic arthralgia, low back pain, pain from traumatic injury, epigastric pain, toothache, etc. It has a good effect of expelling wind and relieving pain and is widely used for various pain syndromes caused by wind-dampness, cold coagulation, qi stagnation, and blood stasis. It is also used for postoperative pain and cancer pain and has a certain analgesic effect. For skin diseases such as eczema, urticaria, and stubborn tinea, Cynanchum paniculatum has the effect of expelling wind and relieving itching. In addition, Cynanchum paniculatum can also detoxify snake venom and treat snake bites.

[0045] Epimedium brevicornum: Warm in nature, pungent, sweet in taste. It acts on the liver and kidney meridians. It can tonify the kidney and strengthen yang, dispel wind and dampness, and benefit essence and strengthen bones. It is used to treat impotence, spermatorrhea, frequent urination, soreness and weakness of the waist and knees caused by kidney yang deficiency; joint pain, limb numbness, and adverse movement of muscles and bones caused by wind-cold-dampness arthralgia.

[0046] Olibanum: Pungent; bitter; warm in nature; it acts on the heart, liver, and spleen meridians. It is used for promoting blood circulation to activate qi and relieve pain, reducing swelling and promoting granulation. It is mainly used for chest impediment pain, epigastric pain, dysmenorrhea and amenorrhea, postpartum stasis, abdominal mass pain, rheumatic arthralgia, muscle spasm, traumatic injury, carbuncle and sore.

[0047] Polygonum perfoliatum: Bitter, sour, sweet in taste, cool in nature. Meridians entered: lung, bladder, spleen meridians. It can clear heat and detoxify, promote diuresis and reduce swelling, and disperse stasis and relieve pain. It is used to treat cough due to lung heat, edema, gonorrhea, redness of the eyes, traumatic injury, scald.

[0048] Carthamus tinctorius: Sweet, pungent, warm in taste; it acts on the liver and heart meridians. It can promote blood circulation to remove blood stasis, dredge meridians, and relieve swelling and pain. It is used to treat amenorrhea, dysmenorrhea, retention of lochia, abdominal mass, chest impediment pain, stasis abdominal pain, chest and hypochondrium stabbing pain, traumatic injury, swelling and pain of sores and ulcers.

[0049] Cibotium barometz: Bitter, slightly sweet in taste, warm in nature. It acts on the liver and kidney meridians. It has the effects of tonifying the liver and kidney, strengthening the lumbar spine, dispelling wind and dampness, and promoting joint movement. It is used to treat symptoms such as lumbar pain and stiffness, difficulty in bending and extending, knee pain and weakness of the feet, weakness of muscles and bones, urinary incontinence, and leukorrhea in women caused by deficiency of the liver and kidney.

[0050] Pteris multifida Poir: Bitter in taste; cold in nature; it acts on the large intestine and bladder meridians. It has the effects of clearing heat and promoting diuresis, detoxifying and stopping dysentery, cooling blood and stopping bleeding. It is used to treat diseases such as dysentery caused by heat toxin or damp-heat, diarrhea, etc. It can also be used to treat diseases such as hematuria, hematochezia, hemorrhoids bleeding, strangury, and damp-heat jaundice caused by blood heat.

[0051] Myrrh: Pungent, bitter in taste; neutral in nature; it acts on the heart, liver, and spleen meridians. It has the effects of dispersing stasis and relieving pain, reducing swelling and promoting granulation; it is used for the treatment of diseases such as chest impediment pain, epigastric pain, dysmenorrhea and amenorrhea, postpartum stasis, abdominal mass pain, rheumatic arthralgia, traumatic injury, carbuncle and sore.

[0052] Cyathula officinalis Kuan: Sweet and bitter in taste; neutral in property. Acting on the liver and kidney meridians. Expelling wind and removing dampness, dredging channels and activating blood circulation. Treating lumbar and knee pain caused by wind-dampness, flaccidity of the feet and cramps of tendons, arthralgia, foot spasm, or flaccidity of the feet, lumbar and leg pain caused by wind-dampness, and pain and deformation of lower limb joints. Blood syndromes: bloody stranguria and hematuria, amenorrhea and mass in the abdomen, swelling and pain caused by falls and injuries, and guiding fire downward.

[0053] Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex Franch. et Sav.: Pungent in taste; warm in property. Acting on the lung, stomach and large intestine meridians. Relieving exterior syndrome and dispelling cold, expelling wind and relieving pain, promoting nasal passage, drying dampness and arresting leukorrhea, detumescence and discharging pus. Treating headache, toothache, pain in the supraorbital ridge, rheumatic arthralgia, swelling and pain of sores and ulcers, and skin pruritus due to wind-dampness.

[0054] Pheretima aspergillum (E. Perrier): Salty and cold in taste. Acting on the liver, spleen and bladder meridians. Having the effects of clearing heat and calming endogenous wind, dredging channels, relieving asthma and inducing diuresis. Having antipyretic effect, hemolytic effect, slow and persistent hypotensive effect, sedative and anticonvulsant effect, and bronchodilating effect. Treating high fever and restlessness, infantile convulsion; treating schizophrenia belonging to the type of heat mania; treating asthma with wheezing due to lung heat, coughing yellow and thick phlegm and unable to lie flat; also treating hot arthralgia with red, swollen, hot and painful joints and difficult flexion and extension; dysuria and pain due to calculus stranguria caused by heat accumulation, and hypertension due to hyperactivity of liver yang.

[0055] The present invention is developed by the inventor through years of medical practice, careful research, continuous improvement and perfection of the formula. Through continuous research and improvement of the formula, and follow-up of the curative effect and telephone return visit to patients, it is finally found that adding Rheum officinale Baill., Olibanum, Myrrha, Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex Franch. et Sav. to the formula can achieve satisfactory curative effects in the treatment of lumbar disc herniation, cervical spondylosis, scapulohumeral periarthritis, lumbar muscle strain, hyperosteogeny, rheumatic arthritis, tennis elbow and other diseases. Thus, the best composition of traditional Chinese medicine for treating lumbar disc herniation and pain in the shoulder, neck and waist of the present invention is formed: Rheum officinale Baill., Desmodium sequax Wall., Uraria crinita (L.) Desv. ex DC., Saposhnikovia divaricata (Turcz.) Schischk., Angelica sinensis (Oliv.) Diels, Morus alba L., Curculigo orchioides Gaertn., Prunus persica (L.) Batsch, Agrimonia pilosa Ledeb., Cynanchum paniculatum (Bunge) Kitag., Epimedium brevicornu Maxim., Olibanum, Microcos paniculata L., Carthamus tinctorius L., Cibotium barometz (L.) J. Sm., Pteris multifida Poir., Myrrha, Cyathula officinalis Kuan, Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex Franch. et Sav., Pheretima aspergillum (E. Perrier).

[0056] The beneficial effects of the present invention are:

[0057] 1. Simple formula and scientific compatibility. Neck, shoulder, waist and leg pain is mostly caused by damaged meridians after trauma, qi stagnation and blood stasis, swelling and pain. Externally, wind-cold-damp pathogens invade and block the meridians. Due to long-term fatigue in the middle-aged and elderly, if they overwork for a long time and use force unevenly, it will damage the limb muscles, fascia, ligaments and joints, and then be infected by wind-cold-damp pathogens, resulting in blockage of local collaterals, qi stagnation and blood stasis, and pain due to obstruction. The treatment should use the methods of reducing swelling and alleviating pain, promoting qi and activating blood circulation, removing blood stasis and dredging meridians, and dispelling dampness. The traditional Chinese medicine components of the present invention: Rhubarb removes blood stasis and dredges meridians; Frankincense and Wild Celery Root reduce swelling and alleviate pain; Golden Chicken Tail, Saposhnikovia Divaricata and Chinese Clematis Stem promote qi and dredge meridians; Angelica Sinensis and Safflower promote blood circulation and remove blood stasis; Mulberry Leaf, Goldhair Fern Rhizome and Curculigo Rhizome clear heat and detoxify, have antibacterial and anti-inflammatory effects, can treat eczema and damp sores, and can effectively prevent skin allergies caused by external use of drugs; Pteris Multifida Poir., Peach Kernel, Myrrh and Agrimony promote blood circulation to remove stasis, clear heat and promote diuresis; Cyathula Officinalis Kuan, Pyrola Decumbens Miq. and Dahurian Angelica Root dispel wind-dampness, dredge meridians and relieve pain; Epimedium Sagittatum, Earthworm dispel wind and dampness, benefit essence and strengthen bones, clear heat and calm endogenous wind, and dredge collaterals. The combination of various herbs can make the medicine penetrate the skin and reach the affected area effectively, which is an excellent prescription for treating lumbar disc herniation, neck, shoulder, waist and leg pain.

[0058] 2. Diverse dosage forms and strong practicability. The traditional Chinese medicine components of the present invention can be made into various dosage forms, which can be made into suitable dosage forms according to different people, different applicable parts and different diseases, are convenient to carry, and are economical and practical.

[0059] 3. Traditional Chinese medicine formula, safe and non-toxic. The traditional Chinese medicine components of the present invention have passed pathological toxicity tests, have no toxic and side effects, and are not allergic to the skin.

[0060] 4. Multiple indications and remarkable curative effects. The present invention has been verified by clinical curative effects, and the comprehensive effective rate for the treatment of lumbar disc herniation, scapulohumeral periarthritis, cervical spondylosis, lumbar muscle strain, hyperosteogeny, rheumatoid arthritis, tennis elbow, etc. is as high as 97.52%. Detailed implementation mode

[0061] The following further illustrates the present invention in conjunction with specific embodiments, but does not indicate the limitation of the claims of the present invention.

[0062] Example 1: Ointment

[0063] Formula: 70 parts of Rhubarb, 70 parts of Wild Celery Root, 70 parts of Golden Chicken Tail, 70 parts of Saposhnikovia Divaricata, 70 parts of Angelica Sinensis, 70 parts of Mulberry Leaf, 70 parts of Curculigo Rhizome, 70 parts of Peach Kernel, 70 parts of Agrimony, 70 parts of Pyrola Decumbens Miq., 70 parts of Epimedium Sagittatum, 70 parts of Frankincense, 70 parts of Chinese Clematis Stem, 70 parts of Safflower, 70 parts of Goldhair Fern Rhizome, 70 parts of Pteris Multifida Poir., 70 parts of Myrrh, 70 parts of Cyathula Officinalis Kuan, 70 parts of Dahurian Angelica Root, 70 parts of Earthworm.

[0064] Manufacturing method:

[0065] (1) Grind Rheum officinale, Homalomena cochinchinensis, Campanumoea javanica, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Olibanum, Microstegium vimineum, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Myrrha, Cyathula officinalis, Angelica dahurica, Pheretima aspergillum into coarse powder, mix evenly, percolate with 55% ethanol, and concentrate the percolate into an extract with a relative density of 1.10 - 1.20. This extract is used as the active ingredient of the drug of the present invention.

[0055] (2) Take the above extract, add a suitable blank matrix (such as petrolatum, paraffin wax, liquid paraffin, silicone oil, beeswax, lanolin, etc.; polyethylene glycol, glycerogelatin, starch glycerin, sodium methylcellulose, sodium carboxymethylcellulose, etc.) and mix evenly. Then add a moisturizer, preservative, antioxidant, transdermal penetration enhancer, etc. and stir evenly. Fill it into an ointment tube to obtain the product.

[0066] Dosage and administration: Apply the ointment on sterile double-copy paper, non-woven plaster empty stickers with anti-seepage rings or other medical dressings. Determine the area according to the part, with a thickness of 0.2 - 0.5 mm, and apply it to the painful part. Change the dressing once every 24 hours.

[0067] Example 2: Ointment

[0068] Formulation: 45 parts of Rheum officinale, 45 parts of Homalomena cochinchinensis, 45 parts of Campanumoea javanica, 90 parts of Saposhnikovia divaricata, 45 parts of Angelica sinensis, 45 parts of Morus alba, 45 parts of Curculigo orchioides, 45 parts of Prunus persica, 45 parts of Agrimonia pilosa, 45 parts of Cynanchum paniculatum, 45 parts of Epimedium brevicornu, 90 parts of Olibanum, 45 parts of Microstegium vimineum, 90 parts of Carthamus tinctorius, 45 parts of Cibotium barometz, 45 parts of Pteris multifida, 45 parts of Myrrha, 45 parts of Cyathula officinalis, 90 parts of Angelica dahurica, 45 parts of Pheretima aspergillum.

[0069] Manufacturing method:

[0070] (1) Grind Rheum officinale, Homalomena cochinchinensis, Campanumoea javanica, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Olibanum, Microstegium vimineum, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Myrrha, Cyathula officinalis, Angelica dahurica, Pheretima aspergillum into coarse powder, mix evenly, and reflux extract with 80% ethanol for 2 - 3 times, each time for 0.5 - 1.5 hours. Concentrate under reduced pressure into an extract with a relative density of 1.00 - 1.20. This extract is used as the active ingredient of the drug of the present invention.

[0071] (2) Take the above extract, add a suitable blank matrix (such as petrolatum, paraffin wax, liquid paraffin, silicone oil, beeswax, lanolin, etc.; polyethylene glycol, glycerogelatin, starch glycerin, sodium methylcellulose, sodium carboxymethylcellulose, etc.) and mix evenly. Then add a moisturizer, preservative, antioxidant, transdermal penetration enhancer, etc. and stir evenly. Fill it into an ointment tube to obtain the product.

[0072] Dosage and administration: The same as in Example 1.

[0073] Example 3: Ointment

[0074] Composition: 90 parts of Rheum officinale, 49 parts of Desmodium sequax Wall., 49 parts of Ophioglossum thermale Kom., 90 parts of Saposhnikovia divaricata (Turcz.) Schischk., 49 parts of Angelica sinensis (Oliv.) Diels, 49 parts of Morus alba L., 49 parts of Curculigo orchioides Gaertn., 49 parts of Prunus persica (L.) Batsch, 49 parts of Agrimonia pilosa Ledeb., 49 parts of Cynanchum paniculatum (Bge.) Kitag., 49 parts of Epimedium brevicornu Maxim., 49 parts of Olibanum, 49 parts of Microglossa pyrifolia (Lam.) Kuntze, 90 parts of Carthamus tinctorius L., 90 parts of Cibotium barometz (L.) J. Sm., 49 parts of Pteris multifida Poir., 49 parts of Myrrha, 90 parts of Cyathula officinalis Kuan, 90 parts of Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex Franch. et Sav., 49 parts of Pheretima aspergillum (E. Perrier).

[0075] Preparation method:

[0076] (1) Grind Rheum officinale, Desmodium sequax Wall., Ophioglossum thermale Kom., Saposhnikovia divaricata (Turcz.) Schischk., Angelica sinensis (Oliv.) Diels, Morus alba L., Curculigo orchioides Gaertn., Prunus persica (L.) Batsch, Agrimonia pilosa Ledeb., Cynanchum paniculatum (Bge.) Kitag., Epimedium brevicornu Maxim., Olibanum, Microglossa pyrifolia (Lam.) Kuntze, Carthamus tinctorius L., Cibotium barometz (L.) J. Sm., Pteris multifida Poir., Myrrha, Cyathula officinalis Kuan, Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex Franch. et Sav., and Pheretima aspergillum (E. Perrier) into fine powder with a particle size of 160 μm, and then pulverize it into ultrafine powder with a particle size of 1.0 - 10 μm in an ultrafine pulverization device. This ultrafine powder is used as the active ingredient of the drug of the present invention.

[0077] (2) Take the above ultrafine powder, add an appropriate blank matrix (such as petrolatum, paraffin, liquid paraffin, silicone oil, beeswax, lanolin, etc.; polyethylene glycol, glycerogelatin, starch glycerin, sodium methylcellulose, sodium carboxymethylcellulose, etc.) and mix evenly. Then add a moisturizer, preservative, antioxidant, transdermal penetration enhancer, etc. and stir evenly, and fill it into an ointment tube to obtain the product.

[0078] Dosage and administration: The same as in Example 1.

[0079] Example 4: Cream

[0080] Composition: 70 parts of Rheum officinale, 70 parts of Desmodium sequax Wall., 70 parts of Ophioglossum thermale Kom., 70 parts of Saposhnikovia divaricata (Turcz.) Schischk., 70 parts of Angelica sinensis (Oliv.) Diels, 70 parts of Morus alba L., 70 parts of Curculigo orchioides Gaertn., 70 parts of Prunus persica (L.) Batsch, 70 parts of Agrimonia pilosa Ledeb., 70 parts of Cynanchum paniculatum (Bge.) Kitag., 70 parts of Epimedium brevicornu Maxim., 70 parts of Olibanum, 70 parts of Microglossa pyrifolia (Lam.) Kuntze, 70 parts of Carthamus tinctorius L., 70 parts of Cibotium barometz (L.) J. Sm., 70 parts of Pteris multifida Poir., 70 parts of Myrrha, 70 parts of Cyathula officinalis Kuan, 70 parts of Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex Franch. et Sav., 70 parts of Pheretima aspergillum (E. Perrier).

[0081] Preparation method:

[0082] (1) Grind Rheum officinale, Desmodium sequax Wall., Ophioglossum thermale Kom., Saposhnikovia divaricata (Turcz.) Schischk., Angelica sinensis (Oliv.) Diels, Morus alba L., Curculigo orchioides Gaertn., Prunus persica (L.) Batsch, Agrimonia pilosa Ledeb., Cynanchum paniculatum (Bge.) Kitag., Epimedium brevicornu Maxim., Olibanum, Microglossa pyrifolia (Lam.) Kuntze, Carthamus tinctorius L., Cibotium barometz (L.) J. Sm., Pteris multifida Poir., Myrrha, Cyathula officinalis Kuan, Angelica dahurica (Fisch. ex Hoffm.) Benth. et Hook. f. ex Franch. et Sav., and Pheretima aspergillum (E. Perrier) into coarse powder, mix evenly, and percolate with 80% ethanol. Concentrate the percolate into an extract with a relative density of 1.00 - 1.20. This extract is used as the active ingredient of the drug of the present invention.

[0083] (2) Add the above extract to a suitable blank matrix (sodium soaps, triethanolamine soaps, polysorbates, fatty alcohol sulfates, sodium fatty alcohol sulfates, calcium soaps, monoglycerides, fatty alcohols, etc.) and mix evenly. Then add moisturizers, preservatives, antioxidants, transdermal penetration enhancers, etc. and stir well. Fill into an ointment tube to obtain the product.

[0084] Dosage and administration: The same as in Example 1.

[0085] Example 5: Cream

[0086] Formulation: 45 parts of Rheum palmatum, 45 parts of Osmorhiza aristata, 45 parts of Campanumoea javanica, 90 parts of Saposhnikovia divaricata, 45 parts of Angelica sinensis, 45 parts of Morus alba, 45 parts of Curculigo orchioides, 45 parts of Prunus persica, 45 parts of Agrimonia pilosa, 45 parts of Cynanchum paniculatum, 45 parts of Epimedium brevicornu, 90 parts of Olibanum, 45 parts of Microglossa pyrifolia, 90 parts of Carthamus tinctorius, 45 parts of Cibotium barometz, 45 parts of Pteris multifida, 45 parts of Myrrha, 45 parts of Cyathula officinalis, 90 parts of Angelica dahurica, 45 parts of Pheretima aspergillum.

[0087] Manufacturing method:

[0078] (1) Grind Rheum palmatum, Osmorhiza aristata, Campanumoea javanica, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Olibanum, Microglossa pyrifolia, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Myrrha, Cyathula officinalis, Angelica dahurica, Pheretima aspergillum into coarse powder, mix evenly, and reflux extract with 80% ethanol for 2 - 3 times, 0.5 - 1.5 hours each time. Concentrate under reduced pressure to an extract with a relative density of 1.00 - 1.20, and use this extract as the active ingredient of the drug of the present invention.

[0089] (2) Add the above extract to a suitable blank matrix (sodium soaps, triethanolamine soaps, polysorbates, fatty alcohol sulfates, sodium fatty alcohol sulfates, calcium soaps, monoglycerides, fatty alcohols, etc.) and mix evenly. Then add moisturizers, preservatives, antioxidants, transdermal penetration enhancers, etc. and stir well. Fill into an ointment tube to obtain the product.

[0090] Dosage and administration: The same as in Example 1.

[0091] Example 6: Cream

[0082] Formulation: 90 parts of Rheum palmatum, 49 parts of Osmorhiza aristata, 49 parts of Campanumoea javanica, 90 parts of Saposhnikovia divaricata, 49 parts of Angelica sinensis, 49 parts of Morus alba, 49 parts of Curculigo orchioides, 49 parts of Prunus persica, 49 parts of Agrimonia pilosa, 49 parts of Cynanchum paniculatum, 49 parts of Epimedium brevicornu, 49 parts of Olibanum, 49 parts of Microglossa pyrifolia, 90 parts of Carthamus tinctorius, 90 parts of Cibotium barometz, 49 parts of Pteris multifida, 49 parts of Myrrha, 90 parts of Cyathula officinalis, 90 parts of Angelica dahurica, 49 parts of Pheretima aspergillum.

[0093] Manufacturing method:

[0094] (1) Grind rhubarb, odorivittate, acrospore of pekin strobilanthes, divaricate saposhnikovia root, Chinese angelica, mulberry leaf, curculigo rhizome, peach kernel, hairyvein agrimony, pyrola, epimedium, frankincense, bamboo pole, safflower, Chinese goldthread rhizome, phoenix-tail grass, myrrh, cyathula root, dahurian angelica root, and earthworm into fine powder with a particle size of 120 μm, and then grind it into superfine powder with a particle size of 0.1 - 40 μm in a superfine pulverizer. This superfine powder is used as the active ingredient of the drug of the present invention.

[0095] (2) Take the above-mentioned extract, add an appropriate blank matrix (sodium soap, triethanolamine soap, polysorbate, fatty alcohol sulfate, sodium lauryl sulfate, calcium soap, monoglyceride, fatty alcohol, etc.), mix well, then add a moisturizer, preservative, antioxidant, transdermal penetration enhancer, etc., stir evenly, and fill into an ointment tube to obtain the product.

[0096] Dosage and administration: The same as in Example 1.

[0097] Example 7: Patch (rubber patch)

[0098] Formulation: 70 parts of rhubarb, 70 parts of odorivittate, 70 parts of acrospore of pekin strobilanthes, 70 parts of divaricate saposhnikovia root, 70 parts of Chinese angelica, 70 parts of mulberry leaf, 70 parts of curculigo rhizome, 70 parts of peach kernel, 70 parts of hairyvein agrimony, 70 parts of pyrola, 70 parts of epimedium, 70 parts of frankincense, 70 parts of bamboo pole, 70 parts of safflower, 70 parts of Chinese goldthread rhizome, 70 parts of phoenix-tail grass, 70 parts of myrrh, 70 parts of cyathula root, 70 parts of dahurian angelica root, 70 parts of earthworm.

[0099] Manufacturing method:

[0100] (1) Grind rhubarb, odorivittate, acrospore of pekin strobilanthes, divaricate saposhnikovia root, Chinese angelica, mulberry leaf, curculigo rhizome, peach kernel, hairyvein agrimony, pyrola, epimedium, frankincense, bamboo pole, safflower, Chinese goldthread rhizome, phoenix-tail grass, myrrh, cyathula root, dahurian angelica root, and earthworm into coarse powder, mix evenly, and percolate with 80% ethanol. Concentrate the percolate into an extract with a relative density of 1.00 - 1.20. This extract is used as the active ingredient of the drug of the present invention.

[0101] (2) Mix the above-mentioned extract with an appropriate transdermal penetration enhancer (borneol, menthol, camphor, azone, etc.), then add an appropriate blank matrix (rubber, thermoplastic rubber, rosin, rosin derivative, vaseline, lanolin, zinc oxide, etc.) to make a coating, apply the coating, cut into sections, cover with a liner, punch holes, and cut into small pieces to obtain the product.

[0102] Example 8: Patch (gel patch)

[0103] Formulation: 45 parts of Rheum officinale, 45 parts of Caulophyllum robustum, 45 parts of Polystichum lepidocaulon, 90 parts of Saposhnikovia divaricata, 45 parts of Angelica sinensis, 45 parts of Morus alba, 45 parts of Curculigo orchioides, 45 parts of Prunus persica, 45 parts of Agrimonia pilosa, 45 parts of Cynanchum paniculatum, 45 parts of Epimedium brevicornu, 90 parts of Olibanum, 45 parts of Microstegium vimineum, 90 parts of Carthamus tinctorius, 45 parts of Cibotium barometz, 45 parts of Pteris multifida, 45 parts of Myrrha, 45 parts of Cyathula officinalis, 90 parts of Angelica dahurica, 45 parts of Pheretima aspergillum.

[0104] Manufacturing method:

[0105] (1) Grind Rheum officinale, Caulophyllum robustum, Polystichum lepidocaulon, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Olibanum, Microstegium vimineum, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Myrrha, Cyathula officinalis, Angelica dahurica, and Pheretima aspergillum into coarse powder, mix evenly, and reflux extract with 60% ethanol for 2 - 3 times, each time for 0.5 - 1.5 hours. Concentrate under reduced pressure to an extract with a relative density of 1.00 - 1.20, and use this extract as the active ingredient of the drug of the present invention.

[0106] (2) Take the above extract and add suitable blank matrices (such as gum arabic, sodium alginate, cellulose and its derivatives, polyacrylic acid and its sodium salts, polyvinyl alcohol, polyvinylpyrrolidone, glycerol, microcrystalline silica, etc.), humectants (such as glycerol, propylene glycol, polyethylene glycol, sorbitol, etc.), fillers (such as titanium dioxide, calcium carbonate, kaolin, zinc oxide, etc.), and transdermal absorption promoters (such as azone, dimethyl sulfoxide, urea, menthol, borneol, eucalyptus oil, etc.), mix evenly, apply it on the backing material (common backing materials include cotton cloth, non-woven fabric, paper, etc.), cover liner (common cover liner materials include anti-sticking paper, plastic film, aluminum foil - polyethylene composite film, rigid gauze, etc.), cut, package, and store in a sealed manner.

[0107] Example 9: Plaster (hot melt adhesive patch)

[0108] Formulation: 90 parts of Rheum officinale, 49 parts of Caulophyllum robustum, 49 parts of Polystichum lepidocaulon, 90 parts of Saposhnikovia divaricata, 49 parts of Angelica sinensis, 49 parts of Morus alba, 49 parts of Curculigo orchioides, 49 parts of Prunus persica, 49 parts of Agrimonia pilosa, 49 parts of Cynanchum paniculatum, 49 parts of Epimedium brevicornu, 49 parts of Olibanum, 49 parts of Microstegium vimineum, 90 parts of Carthamus tinctorius, 90 parts of Cibotium barometz, 49 parts of Pteris multifida, 49 parts of Myrrha, 90 parts of Cyathula officinalis, 90 parts of Angelica dahurica, 49 parts of Pheretima aspergillum.

[0109] Manufacturing method:

[0110] (1) Grind Rheum officinale, Caulophyllum robustum, Polystichum lepidocaulon, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Olibanum, Microstegium vimineum, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Myrrha, Cyathula officinalis, Angelica dahurica, and Pheretima aspergillum into fine powder with a particle size of 180 μm, and then pulverize it into ultrafine powder with a particle size of 0.1 - 40 μm in an ultrafine pulverization device.

[0111] (2) Mix the above fine powder or ultrafine powder with 500 - 600 parts of vaseline to make an ointment for later use. Add hot melt adhesive with a weight 0.075 - 1.5 times that of the ointment and heat it until it melts completely. Then add the above ointment and 0 - 70 parts of transdermal absorption enhancer (one or more of menthol, camphor, and borneol) and mix well to obtain a coating. Apply 6 - 10 g of the coating on paper, non-woven fabric, spunlace fabric, or polyester-cotton fabric, cover it with siliconized paper, plastic film, or aluminum foil - polyethylene composite film, and press it into a square, circular, or oval shape to obtain the product.

[0112] Example 10: Patch (hot melt adhesive patch)

[0113] Formulation: 70 parts of Rheum palmatum, 70 parts of Ligusticum sciadophyllum, 70 parts of Campanumoea javanica, 70 parts of Saposhnikovia divaricata, 70 parts of Angelica sinensis, 70 parts of Morus alba, 70 parts of Curculigo orchioides, 70 parts of Prunus persica, 70 parts of Agrimonia pilosa, 70 parts of Cynanchum paniculatum, 70 parts of Epimedium brevicornu, 70 parts of Boswellia carterii, 70 parts of Artemisia vulgaris, 70 parts of Carthamus tinctorius, 70 parts of Cibotium barometz, 70 parts of Pteris multifida, 70 parts of Commiphora myrrha, 70 parts of Cyathula officinalis, 70 parts of Angelica dahurica, 70 parts of Pheretima aspergillum.

[0114] Manufacturing method:

[0115] (1) Grind Rheum palmatum, Ligusticum sciadophyllum, Campanumoea javanica, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Boswellia carterii, Artemisia vulgaris, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Commiphora myrrha, Cyathula officinalis, Angelica dahurica, and Pheretima aspergillum into a coarse powder, mix them evenly, and reflux extract with 80% ethanol for 2 - 3 times, 0.5 - 1.5 hours each time. Concentrate under reduced pressure to obtain an extract with a relative density of 1.00 - 1.20.

[0116] (2) Dry and pulverize the above extract, mix it evenly with 1 part by weight of vaseline to make an ointment for later use. Take 8 times the weight of the ointment of hot melt adhesive and heat it to 110 - 180 °C until it melts completely. Add the above ointment and transdermal absorption enhancer (one or more of menthol, camphor, and borneol), and the weight of the transdermal enhancer is 3 - 5% of the weight of the ointment. Mix well to obtain a coating. Drop 6 - 10 g of the coating onto paper, non-woven fabric, spunlace fabric, or polyester-cotton fabric, cover it with siliconized paper, plastic film, or aluminum foil - polyethylene composite film, and press it into a square, circular, or oval shape to obtain the product.

[0117] Example 11: Patch (far-infrared magnetic therapy patch)

[0118] Formulation: 90 parts of Rheum palmatum, 49 parts of Ligusticum sciadophyllum, 49 parts of Campanumoea javanica, 90 parts of Saposhnikovia divaricata, 49 parts of Angelica sinensis, 49 parts of Morus alba, 49 parts of Curculigo orchioides, 49 parts of Prunus persica, 49 parts of Agrimonia pilosa, 49 parts of Cynanchum paniculatum, 49 parts of Epimedium brevicornu, 49 parts of Boswellia carterii, 49 parts of Artemisia vulgaris, 90 parts of Carthamus tinctorius, 90 parts of Cibotium barometz, 49 parts of Pteris multifida, 49 parts of Commiphora myrrha, 90 parts of Cyathula officinalis, 90 parts of Angelica dahurica, 49 parts of Pheretima aspergillum.

[0119] Manufacturing method:

[0120] (1) Grind rhubarb, odorivittate, acrospore of multiflorous knotweed, divaricate saposhnikovia root, Chinese angelica, mulberry leaf, curculigo rhizome, peach kernel, hairyvein agrimony, pyrola subaphylla, epimedium herb, frankincense, bamboo pole, safflower, Chinese goldthread rhizome, phoenix-tail grass, myrrh, cyathula root, dahurian angelica root, earthworm into coarse powder, mix evenly, and reflux extract with 80% ethanol for 2 - 3 times, 0.5 - 1.5 hours each time. Concentrate under reduced pressure to obtain an extract with a relative density of 1.00 - 1.20.

[0121] (2) Dry and crush the above extract, mix it evenly with 1-fold weight of vaseline to make an ointment for later use. The ratio of the ointment, hot melt adhesive, far-infrared ceramic powder, rare earth magnetic powder, and transdermal enhancer is 3∶10∶3∶3∶1. Heat the hot melt adhesive to 110 - 180°C to fully melt it, then add the ointment, far-infrared ceramic powder, rare earth magnetic powder, and transdermal absorption enhancer (one or more of menthol, camphor, borneol), mix evenly to make a coating, apply the coating on paper, non-woven fabric, spunlace fabric or polyester-cotton fabric, cover it with siliconized paper, plastic film or aluminum foil - polyethylene composite film, and press it into a square, circular or oval shape to obtain.

[0122] Example 12: Patch (Far-infrared Magnetic Therapy Patch)

[0123] Formula: 70 parts of rhubarb, 70 parts of odorivittate, 70 parts of acrospore of multiflorous knotweed, 70 parts of divaricate saposhnikovia root, 70 parts of Chinese angelica, 70 parts of mulberry leaf, 70 parts of curculigo rhizome, 70 parts of peach kernel, 70 parts of hairyvein agrimony, 70 parts of pyrola subaphylla, 70 parts of epimedium herb, 70 parts of frankincense, 70 parts of bamboo pole, 70 parts of safflower, 70 parts of Chinese goldthread rhizome, 70 parts of phoenix-tail grass, 70 parts of myrrh, 70 parts of cyathula root, 70 parts of dahurian angelica root, 70 parts of earthworm.

[0124] Manufacturing method:

[0125] (1) Grind rhubarb, odorivittate, acrospore of multiflorous knotweed, divaricate saposhnikovia root, Chinese angelica, mulberry leaf, curculigo rhizome, peach kernel, hairyvein agrimony, pyrola subaphylla, epimedium herb, frankincense, bamboo pole, safflower, Chinese goldthread rhizome, phoenix-tail grass, myrrh, cyathula root, dahurian angelica root, earthworm into fine powder with a particle size of 180μm.

[0126] (2) Take the above fine powder and mix it evenly with 540 parts of vaseline to obtain an ointment. Take 1200 parts of hot melt adhesive, heat and melt it, add the obtained ointment, then add 100 parts of far-infrared ceramic powder, 100 parts of rare earth magnetic powder, and 120 parts of transdermal absorption enhancer (one or more of menthol, camphor, borneol), mix evenly to make a coating, apply the coating on paper, non-woven fabric, spunlace fabric or polyester-cotton fabric, cover it with siliconized paper, plastic film or aluminum foil - polyethylene composite film, and press it into a square, circular or oval shape to obtain.

[0127] Example 13: Patch

[0128] Prescription: 70 parts of rhubarb, 70 parts of clematis, 70 parts of golden cockscomb, 70 parts of siler, 70 parts of angelica, 70 parts of mulberry leaves, 70 parts of curculigo, 70 parts of peach kernel, 70 parts of agrimony, 70 parts of cynanchum, 70 parts of epimedium, 70 parts of frankincense, 70 parts of fishing rod, 70 parts of safflower, 70 parts of cibotium barometz, 70 parts of phoenix tail grass, 70 parts of myrrh, 70 parts of cyathula, 70 parts of angelica dahurica, and 70 parts of earthworm.

[0129] Preparation method:

[0130] (1) Grind rhubarb, cyperus rotundus, golden cocktail, saposhnikovia divaricata, angelica sinensis, mulberry leaf, curculigo orchioides, peach kernel, agrimony, cyperus chinensis, epimedium, frankincense, fishing rod, safflower, cibotium barometz, phoenix tail grass, myrrh, cyathula officinalis, angelica dahurica, and earthworm into coarse powder, mix well, extract with 80% ethanol under reflux for 2 to 3 times, each time for 0.5 to 1.5 hours. Concentrate under reduced pressure to obtain an extract with a relative density of 1.00 to 1.20, and use the extract as the active ingredient of the drug of the present invention.

[0131] (2) Take the above extract, add a suitable blank matrix (ethylene-vinyl acetate copolymer, silicone rubber and polyethylene glycol, etc.), surfactant, emulsifier, moisturizer, antibacterial agent, antioxidant or transdermal enhancer, mix well, apply to backing material (common backing materials include cotton cloth, non-woven fabric, paper, etc.), cover with a liner, slice and obtain.

[0132] Example 14: Plaster

[0133] Prescription: 90 parts of rhubarb, 49 parts of clematis, 49 parts of golden cockscomb, 90 parts of siler, 49 parts of angelica, 49 parts of mulberry leaves, 49 parts of curculigo, 49 parts of peach kernel, 49 parts of agrimony, 49 parts of cynanchum, 49 parts of epimedium, 49 parts of frankincense, 49 parts of fishing rod, 90 parts of safflower, 90 parts of cibotium barometz, 49 parts of phoenix tail grass, 49 parts of myrrh, 90 parts of cyathula, 90 parts of angelica dahurica, and 49 parts of earthworm.

[0134] Preparation method:

[0135] (1) Take rhubarb, clematis, golden cocktail, fangfeng, angelica, mulberry leaf, curculigo, peach kernel, agrimony, cynanchum, epimedium, frankincense, fishing rod, safflower, dog spine, phoenix tail grass, myrrh, Sichuan cyathula, angelica, earthworm, cut into sections or pieces, and soak with 1100-1400 parts of edible sesame oil for 36 hours. Put the medicinal materials in a pot and fry until dry (1), extract the medicinal materials (boil until dry and remove the residue), remove the residue, filter; (2), refine the oil; boil until drops of water form beads. (3), make the elixir into paste; remove from the fire, take 350 to 420 parts of red elixir, add to the refined oil, stir well, and collect the paste. (4) Remove fire poison; after the plaster is made, soak it in cold water, change the water once a day, and remove the fire poison in seven days.

[0136] (2) Take the paste, melt it over a low fire, and spread it on paper, cotton cloth, or animal skin.

[0137] Example 15: Gel

[0138] Formulation: 90 parts of Rheum officinale, 49 parts of Clutia bracteata, 49 parts of Carpesium triste, 90 parts of Saposhnikovia divaricata, 49 parts of Angelica sinensis, 49 parts of Morus alba, 49 parts of Curculigo orchioides, 49 parts of Prunus persica, 49 parts of Agrimonia pilosa, 49 parts of Cynanchum paniculatum, 49 parts of Epimedium brevicornu, 49 parts of Olibanum, 49 parts of Microstegium vimineum, 90 parts of Carthamus tinctorius, 90 parts of Cibotium barometz, 49 parts of Pteris multifida, 49 parts of Myrrha, 90 parts of Cyathula officinalis, 90 parts of Angelica dahurica, 49 parts of Pheretima aspergillum

[0139] Preparation method:

[0140] (1) Grind Rheum officinale, Clutia bracteata, Carpesium triste, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Olibanum, Microstegium vimineum, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Myrrha, Cyathula officinalis, Angelica dahurica, and Pheretima aspergillum into coarse powder, mix evenly, and reflux extract with 70% ethanol for 3 times, 0.5 - 1.5 hours each time. Concentrate under reduced pressure to obtain an extract with a relative density of 1.00 - 1.20.

[0141] (2) Add the above extract to a suitable blank matrix (water, glycerol or propylene glycol and cellulose derivatives, carbomer, alginate, gelatin, starch, etc.), mix evenly, then add a pH regulator, preservative, transdermal enhancer, etc., stir evenly, and divide into portions to obtain the product.

[0142] Example 16: Medicated wine

[0143] Formulation: 70 parts of Rheum officinale, 70 parts of Clutia bracteata, 70 parts of Carpesium triste, 70 parts of Saposhnikovia divaricata, 70 parts of Angelica sinensis, 70 parts of Morus alba, 70 parts of Curculigo orchioides, 70 parts of Prunus persica, 70 parts of Agrimonia pilosa, 70 parts of Cynanchum paniculatum, 70 parts of Epimedium brevicornu, 70 parts of Olibanum, 70 parts of Microstegium vimineum, 70 parts of Carthamus tinctorius, 70 parts of Cibotium barometz, 70 parts of Pteris multifida, 70 parts of Myrrha, 70 parts of Cyathula officinalis, 70 parts of Angelica dahurica, 70 parts of Pheretima aspergillum

[0144] Preparation method:

[0145] (1) Grind Rheum officinale, Clutia bracteata, Carpesium triste, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Olibanum, Microstegium vimineum, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Myrrha, Cyathula officinalis, Angelica dahurica, and Pheretima aspergillum into coarse powder.

[0146] (2) Place the above coarse powder and 3000 parts of Chinese liquor in a sealed container, seal and soak (usually for more than 30 days), stir regularly, take the supernatant, press the medicinal residues, combine the pressing liquid with the above clear liquid, stir evenly, then let it stand and settle (usually for more than 14 days), and filter and fill into containers to obtain the product.

[0147] Example 17: Tincture

[0148] Composition: 45 parts of Rheum officinale, 45 parts of Caulophyllum robustum, 45 parts of Polystichum lepidocaulon, 90 parts of Saposhnikovia divaricata, 45 parts of Angelica sinensis, 45 parts of Morus alba, 45 parts of Curculigo orchioides, 45 parts of Prunus persica, 45 parts of Agrimonia pilosa, 45 parts of Cynanchum paniculatum, 45 parts of Epimedium brevicornu, 90 parts of Olibanum, 45 parts of Microstegium vimineum, 90 parts of Carthamus tinctorius, 45 parts of Cibotium barometz, 45 parts of Pteris multifida, 45 parts of Myrrha, 45 parts of Cyathula officinalis, 90 parts of Angelica dahurica, 45 parts of Pheretima aspergillum.

[0149] Manufacturing method:

[0150] (1) Grind Rheum officinale, Caulophyllum robustum, Polystichum lepidocaulon, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Olibanum, Microstegium vimineum, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Myrrha, Cyathula officinalis, Angelica dahurica, and Pheretima aspergillum into coarse powder, mix evenly, and reflux extract with 70% ethanol twice, each time for 0.5 - 1.5 hours. Concentrate under reduced pressure to an extract with a relative density of 1.00 - 1.20.

[0151] (2) Dissolve or dilute the above extract with ethanol, stir evenly, let stand, filter, and then fill into containers to obtain the product.

[0152] Example 18: Aerosol

[0153] Composition: 70 parts of Rheum officinale, 70 parts of Caulophyllum robustum, 70 parts of Polystichum lepidocaulon, 70 parts of Saposhnikovia divaricata, 70 parts of Angelica sinensis, 70 parts of Morus alba, 70 parts of Curculigo orchioides, 70 parts of Prunus persica, 70 parts of Agrimonia pilosa, 70 parts of Cynanchum paniculatum, 70 parts of Epimedium brevicornu, 70 parts of Olibanum, 70 parts of Microstegium vimineum, 70 parts of Carthamus tinctorius, 70 parts of Cibotium barometz, 70 parts of Pteris multifida, 70 parts of Myrrha, 70 parts of Cyathula officinalis, 70 parts of Angelica dahurica, 70 parts of Pheretima aspergillum.

[0154] Manufacturing method:

[0155] (1) Grind Rheum officinale, Caulophyllum robustum, Polystichum lepidocaulon, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Olibanum, Microstegium vimineum, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Myrrha, Cyathula officinalis, Angelica dahurica, and Pheretima aspergillum into coarse powder, mix evenly, and reflux extract with 85% ethanol twice, each time for 0.5 - 1.5 hours. Concentrate under reduced pressure to an extract with a relative density of 1.00 - 1.20.

[0156] (2) Mix the above extract with ethanol, filter, then add antioxidants, surfactants, preservatives, transdermal penetration enhancers, etc., mix evenly, fill into a pressure-resistant container, seal, and fill with an appropriate amount of propellant (the propellant can be a compressed gas such as tetrafluoroethane, heptafluoropropane, etc.) to obtain the product. (Mix water, glycerol or propylene glycol with cellulose derivatives, carbomer, alginate, gelatin, starch, etc.), then add a pH regulator, preservative, transdermal penetration enhancer, etc., stir evenly, and subpackage to obtain the product.

[0157] Example 19: Spray

[0158] Formulation: 70 parts of Rheum officinale, 70 parts of Caulophyllum robustum, 70 parts of Polystichum lepidocaulon, 70 parts of Saposhnikovia divaricata, 70 parts of Angelica sinensis, 70 parts of Morus alba, 70 parts of Curculigo orchioides, 70 parts of Prunus persica, 70 parts of Agrimonia pilosa, 70 parts of Cynanchum paniculatum, 70 parts of Epimedium brevicornu, 70 parts of Olibanum, 70 parts of Microstegium vimineum, 70 parts of Carthamus tinctorius, 70 parts of Cibotium barometz, 70 parts of Pteris multifida, 70 parts of Myrrha, 70 parts of Cyathula officinalis, 70 parts of Angelica dahurica, 70 parts of Pheretima aspergillum.

[0159] Preparation method:

[0160] (1) Grind Rheum officinale, Caulophyllum robustum, Polystichum lepidocaulon, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Olibanum, Microstegium vimineum, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Myrrha, Cyathula officinalis, Angelica dahurica, and Pheretima aspergillum into coarse powder, mix evenly, and reflux extract with 80% ethanol twice, each time for 0.5 - 1.5 hours. Concentrate under reduced pressure to obtain an extract with a relative density of 1.00 - 1.20.

[0161] (2) Mix the above extract with a suitable solvent, then add solubilizers, antioxidants, surfactants, preservatives, transdermal enhancers, etc., stir evenly, and fill into a spray bottle to obtain the product.

[0162] Example 20: Film

[0163] Formulation: 70 parts of Rheum officinale, 70 parts of Caulophyllum robustum, 70 parts of Polystichum lepidocaulon, 70 parts of Saposhnikovia divaricata, 70 parts of Angelica sinensis, 70 parts of Morus alba, 70 parts of Curculigo orchioides, 70 parts of Prunus persica, 70 parts of Agrimonia pilosa, 70 parts of Cynanchum paniculatum, 70 parts of Epimedium brevicornu, 70 parts of Olibanum, 70 parts of Microstegium vimineum, 70 parts of Carthamus tinctorius, 70 parts of Cibotium barometz, 70 parts of Pteris multifida, 70 parts of Myrrha, 70 parts of Cyathula officinalis, 70 parts of Angelica dahurica, 70 parts of Pheretima aspergillum.

[0164] Preparation method:

[0165] (1) Grind Rheum officinale, Caulophyllum robustum, Polystichum lepidocaulon, Saposhnikovia divaricata, Angelica sinensis, Morus alba, Curculigo orchioides, Prunus persica, Agrimonia pilosa, Cynanchum paniculatum, Epimedium brevicornu, Olibanum, Microstegium vimineum, Carthamus tinctorius, Cibotium barometz, Pteris multifida, Myrrha, Cyathula officinalis, Angelica dahurica, and Pheretima aspergillum into coarse powder, mix evenly, and percolate with 80% ethanol. Concentrate the percolate to obtain an extract with a relative density of 1.00 - 1.20.

[0166] (2) Soak a suitable film-forming material (such as polyvinyl alcohol, acrylic resin, and cellulose) in an appropriate solvent, then add the extract and suitable additives (plasticizers: glycerol, sorbitol, etc.; surfactants: polysorbate 80, sodium dodecyl sulfate, etc.; fillers: calcium carbonate, starch, etc.; colorants: pigments, TiO2, etc.), mix evenly, let stand, remove the bubbles, and then coat with a film-forming agent. Dry and sterilize the coating with hot air (80°C - 100°C), and make single-dose grid packaging by hot pressing or cold pressing and scratching according to the dose to obtain the product.

[0167] The above description of the embodiments is to enable those of ordinary skill in the art to understand and use the invention. It is obvious that those skilled in the art can easily make various modifications to these embodiments and apply the general principles described herein to other embodiments without creative labor. Therefore, the present invention is not limited to the above embodiments, and the improvements and modifications made by those skilled in the art without departing from the scope of the present invention should be within the protection scope of the present invention.

[0168] To demonstrate the therapeutic effects of the traditional Chinese medicine composition of the present invention on lumbar disc herniation, cervical spondylosis, scapulohumeral periarthritis, lumbar muscle strain, hyperosteogeny, rheumatoid arthritis, tennis elbow, etc., the inventor conducted relevant pathological toxicity tests and clinical efficacy comparative studies on this drug.

[0169] Pathological toxicity test:

[0170] Taking rabbits as the objects of toxicity test: Six rabbits were selected and divided into a control group and an experimental group, with 3 rabbits in each group. The control group was controlled with clear water. The experimental group used the ointment of the present invention.

[0171] Test method:

[0172] Control group: For 3 rabbits, the rabbit hair on their abdominal parts was shaved off and cleaned, with an area of 9 cm 2 in size. On their outer skin surfaces, clear water was applied once a day for a continuous week, and the rabbits were observed to be normal.

[0173] Experimental group: For 3 rabbits, the rabbit hair on their abdomens was shaved off and cleaned, with an area of 9 cm 2 . On the clean skin surfaces, the ointment prepared in Example 3 of the present invention was respectively applied once a day, with the usage and dosage the same as described above, and the dressing was changed once every 24 hours for a continuous week. No abnormalities were observed in the rabbits, indicating that the traditional Chinese medicine composition method of the present invention has no toxic and side effects on rabbits.

[0174] Clinical efficacy observation

[0175] All the prescriptions of the present invention are prepared with traditional Chinese medicines, with high safety and no toxic and side effects. In clinical practice, since 2013, the inventor has conducted clinical treatment observations on patients and has not found any adverse reactions of the present invention on patients. The present invention has significant curative effects on diseases such as lumbar disc herniation, scapulohumeral periarthritis, cervical spondylosis, lumbar muscle strain, hyperosteogeny, rheumatoid arthritis, tennis elbow, etc. The overall effective rate for shoulder, neck, and low back pain is as high as 97.52%.

[0176] Clinical efficacy observation of the present invention for cervical spondylosis:

[0177] According to the "Diagnostic and Curative Effect Standards for Traditional Chinese Medicine Diseases" of the State Administration of Traditional Chinese Medicine, the diagnostic basis and curative effect evaluation standards for cervical spondylosis are formulated.

[0178] Diagnostic basis for cervical spondylosis:

[0179] 1. There is a history of chronic strain or trauma. Or there are congenital cervical spine deformities or cervical spondylosis.

[0180] 2. It mostly occurs in middle-aged people over 40 years old, those who work with their heads down for a long time or are used to watching TV or videos for a long time, and often shows a chronic onset.

[0181] 3. Shoulder and neck pain, headache and dizziness, neck stiffness, and numbness in the upper limbs.

[0182] 4. The neck movement function is limited. There is often tenderness at the spinous processes of the diseased cervical vertebrae and the inner upper corner of the scapula on the affected side. A cord-like induration of bone hyperplasia can be felt. There may be weakened upper limb muscle strength and muscle atrophy. The brachial plexus traction test is positive. The head pressure test is positive.

[0183] 5. The X-ray anteroposterior radiograph shows hyperplasia of the uncovertebral joint. There may be deviation of the odontoid process in the open-mouth view. The lateral radiograph shows a straightening of the cervical curvature, a narrowing of the intervertebral space, bone hyperplasia or ligament calcification. The oblique radiograph shows a smaller intervertebral foramen. CT and magnetic resonance examinations are meaningful for qualitative and locational diagnosis.

[0184] Evaluation of the curative effect of cervical spondylosis:

[0185] 1. Cured: The original symptoms disappear, the neck and limb functions return to normal, and the patient can participate in normal labor and work.

[0186] 2. Improved: The original symptoms of each type are alleviated, the shoulder, neck, and back pain is reduced, and the neck and limb functions are improved.

[0187] 3. Not cured: The symptoms have not improved.

[0188] Clinical data

[0189] Treatment group: 62 patients with clinically diagnosed cervical spondylosis (nerve root type), 32 males and 30 females, with an average age of 41 years. The shortest medical history is 2 years and the longest is 11 years. Among them, 35 cases have simple local neck pain and limited movement, and 27 cases have bone hyperplasia, neck pain accompanied by numbness in the upper limbs. Control group: 51 patients with cervical spondylosis (nerve root type) for comparison during the same period. The two groups are comparable in terms of gender, age, disease course, etc. after statistical processing.

[0190] Treatment method: The present invention conducts a comparative treatment on cases of cervical spondylosis. The treatment group uses the ointment prepared according to the traditional Chinese medicine composition method of the present invention in Example 3 for external application treatment, changing the dressing every day and applying for 24 hours. The control group selects Shangshi Zhitong Plaster for treatment, one plaster per day, so as to analyze the curative effect of the present invention. The result analysis is shown in Table 1.

[0191] Table 1: Therapeutic effect of the traditional Chinese medicine composition method of the present invention on cervical spondylosis

[0192] Total number of cases Cured Improved Not cured Total effective rate Treatment group 62 45 14 3 95.16％ Control group 51 14 16 21 58.82％

[0193] Total effective rate = (number of cured + improved cases) / total number of cases × 100%. There was a significant difference in the total effective rates between the two groups after χ 2 test (P < 0.01).

[0194] Clinical efficacy observation of the present invention on scapulohumeral periarthritis:

[0195] The diagnostic criteria and efficacy evaluation criteria for scapulohumeral periarthritis were formulated according to the Diagnostic and Therapeutic Criteria of Traditional Chinese Medicine Diseases by the State Administration of Traditional Chinese Medicine.

[0196] Diagnostic criteria for scapulohumeral periarthritis:

[0197] 1. Caused by chronic strain, trauma to the muscles and bones, deficiency of qi and blood, and then being affected by wind-cold-damp pathogens.

[0198] 2. The onset age is around 50 years old. The incidence rate in females is higher than that in males. The right shoulder is more affected than the left shoulder. It is more common in manual laborers and mostly has a chronic onset.

[0199] 3. Shoulder pain, especially severe at night, often induced by weather changes and fatigue, with limited range of motion of the shoulder joint.

[0200] 4. Muscle atrophy of the shoulder, tenderness in the front, back and lateral sides of the shoulder, obvious limitation of abduction function, showing the typical "hiking shoulder" phenomenon.

[0201] 5. X-ray examination is mostly negative. Osteoporosis can be seen in those with a long course of disease.

[0202] Efficacy evaluation of scapulohumeral periarthritis:

[0203] 1. Cured: Shoulder pain disappears, and the function of the shoulder joint is completely or basically restored.

[0204] 2. Improved: Shoulder pain is relieved, and the range of motion is improved.

[0205] 3. Not cured: Symptoms have no improvement.

[0206] Clinical data

[0207] Treatment group: 49 patients with clinically diagnosed scapulohumeral periarthritis, including 35 males and 14 females, with an average age of 55 years. The shortest medical history was 1 week, and the longest was half a year. Among them, 29 cases had only shoulder and neck pain, and 20 cases had limited movement. Control group: 39 patients with scapulohumeral periarthritis for comparison during the same period. There was comparability in gender, age, course of disease, etc. between the two groups after statistical processing.

[0208] Treatment method: The present invention was used for comparative treatment of scapulohumeral periarthritis cases. The treatment group was treated by external application of the ointment prepared according to the Chinese medicine composition method of the present invention in Example 3, with dressing changed every day and applied for 24 hours. The control group was treated with Shiang Shi Tze Tong Pao, one patch per day, so as to analyze the efficacy of the present invention. The result analysis is shown in Table 2.

[0209] Table 2: Therapeutic Effect of the Traditional Chinese Medicine Composition Method of the Present Invention on Scapulohumeral Periarthritis

[0210] Total number of cases Cured Improved Not cured Total effective rate Treatment group 49 40 9 0 100％ Control group 39 7 13 19 51.28％

[0211] Total effective rate = (number of cured + improved cases) / total number of cases × 100%. The total effective rates of the two groups were significantly different after χ 2 test (P < 0.01).

[0212] Clinical Efficacy Observation of the Present Invention on Lumbar Disc Herniation:

[0213] The diagnostic criteria and efficacy evaluation criteria for lumbar disc herniation were formulated according to the "Diagnostic and Therapeutic Criteria for Traditional Chinese Medicine Diseases" of the State Administration of Traditional Chinese Medicine of China.

[0214] Diagnostic Criteria for Lumbar Disc Herniation:

[0215] 1. There is a history of lumbar trauma, chronic strain or exposure to cold and dampness. Most patients have a history of chronic low back pain before the onset of the disease.

[0216] 2. It often occurs in young and middle-aged people.

[0217] 3. The low back pain radiates to the buttocks and lower limbs, and the pain intensifies when the abdominal pressure increases (such as coughing, sneezing).

[0218] 4. Scoliosis of the spine, disappearance of the lumbar physiological curvature, tenderness on the side of the diseased part of the vertebra, radiating to the lower limbs, and limited lumbar movement.

[0219] 5. There is hypersensitivity or hypoesthesia in the area innervated by the affected nerve in the lower limbs. Muscle atrophy may occur in patients with a long course of disease. The straight leg raising or strengthening test is positive, the knee and Achilles tendon reflexes are weakened or disappeared, and the dorsal extension force of the big toe is weakened.

[0220] 6. X-ray film examination: Scoliosis of the spine, disappearance of the lumbar physiological lordosis, the diseased intervertebral disc may become narrower, and there is osteophyte hyperplasia at the adjacent edges. CT examination can show the location and degree of the intervertebral disc herniation.

[0221] Efficacy Evaluation of Lumbar Disc Herniation:

[0222] 1. Cured: The original symptoms of low back pain and leg pain disappear, and the patient can resume the original work when the straight leg raising is more than 70°.

[0223] 2. Improved: The original low back pain and leg pain are relieved, and the lumbar movement function is improved.

[0224] 3. Not cured: The symptoms and signs have not improved.

[0225] Clinical Data

[0226] Treatment group: 42 patients with lumbar disc herniation who were clearly diagnosed clinically, including 25 males and 17 females, with an average age of 52 years. The shortest medical history was 1 month and the longest was 9 years. The main symptoms were low back pain and limited mobility in 23 cases, and osteophytes, radiating pain in the lower extremities accompanied by numbness in 19 cases. Control group: 48 patients with lumbar disc herniation who were treated for comparison during the same period. The two groups were comparable in terms of gender, age, disease course, etc. after statistical processing.

[0227] Treatment method: The present invention conducts comparative treatment on cases of lumbar disc herniation. The treatment group uses the ointment prepared from the traditional Chinese medicine composition of the present invention according to Example 3 for external application treatment, changing the dressing every day and applying for 24 hours. The control group selects Shiang Shi Tung Pao for treatment, applying one patch every day, so as to analyze the curative effect of the present invention. The result analysis is shown in Table 3.

[0228] Table 3: Therapeutic effect of the traditional Chinese medicine composition method of the present invention on lumbar disc herniation

[0229] Total number of cases Cured Improved Not cured Total effective rate Treatment group 42 35 5 2 95.24％ Control group 48 8 12 28 41.67％

[0230] Total effective rate = (number of cured + improved) cases / total number of cases × 100%. The total effective rates of the two groups had significant differences after X 2 test (P < 0.01).

[0231] Clinical efficacy observation of the present invention for lumbar muscle strain:

[0232] The diagnostic basis and efficacy evaluation criteria for lumbar muscle strain are formulated according to the "Diagnostic and Therapeutic Criteria for Traditional Chinese Medicine Diseases" of the State Administration of Traditional Chinese Medicine.

[0233] Diagnostic basis for lumbar muscle strain:

[0234] 1. There is a long history of low back pain with repeated attacks.

[0235] 2. There is soreness and discomfort on one or both sides of the lumbosacral region, which is sometimes mild and sometimes severe, lingering and not healing. It gets worse after fatigue and alleviates after rest.

[0236] 3. There is mild tenderness on one or both sides of the sacrospinal muscle, and there is generally no obvious obstacle to the movement of the waist and legs.

[0237] Efficacy evaluation of lumbar muscle strain:

[0238] 1. Cured: The low back pain symptoms disappear and the waist can move freely.

[0239] 2. Improved: The low back pain is alleviated and the waist movement function is basically restored.

[0240] 3. Not cured: The symptoms have not improved.

[0241] Clinical data

[0242] Treatment group: 38 patients with clinically diagnosed lumbar muscle strain, including 20 males and 18 females, with an average age of 40 years. The shortest medical history was 3 months and the longest was 2 years. The main symptoms were low back pain and limited movement. Control group: 31 patients with lumbar muscle strain treated for comparison during the same period. The two groups were comparable in terms of gender, age, disease course, etc. after statistical processing.

[0243] Treatment method: The present invention conducts comparative treatment on cases of lumbar muscle strain. The treatment group uses the ointment prepared according to the traditional Chinese medicine composition method of the present invention in Example 3 for external application treatment, changing the dressing every day and applying for 24 hours. The control group selects Shiang Shi Tze Tung Pao for treatment, applying one patch every day, so as to analyze the curative effect of the present invention. The result analysis is shown in Table 4.

[0244] Table 4: Therapeutic effect of the traditional Chinese medicine composition method of the present invention on lumbar muscle strain

[0245] Total number of cases Cured Improved Not cured Total effective rate Treatment group 38 30 8 0 100％ Control group 31 7 11 13 58.06％

[0246] Total effective rate = (number of cured + improved) cases / total number of cases × 100%. The total effective rates of the two groups had significant differences after χ 2 test (P < 0.01).

[0247] Clinical efficacy observation of the present invention for rheumatoid arthritis:

[0248] The diagnostic basis and efficacy evaluation criteria for rheumatoid arthritis are formulated according to the "Diagnostic and Therapeutic Criteria for Traditional Chinese Medicine Diseases" of the State Administration of Traditional Chinese Medicine.

[0249] Diagnostic basis for rheumatoid arthritis:

[0250] 1. The main manifestation is migratory pain in the large joints of the extremities, accompanied by heaviness, soreness, numbness, and limited joint flexion and extension. There are often symptoms such as aversion to cold and fever.

[0251] 2. There is often a history of pharyngitis or tonsillitis before the disease, or a history of wading in water, getting caught in the rain, or living in a damp place for a long time.

[0252] 3. Some patients may have low fever, annular erythema of the extremities, or nodular erythema. The heart is often involved.

[0253] 4. The erythrocyte sedimentation rate is increased, and the antistreptolysin "O" is greater than 500 units.

[0254] Efficacy evaluation of rheumatoid arthritis:

[0255] 1. Cured: Symptoms disappear, joint movement is normal, and laboratory tests are normal.

[0256] 2. Improved: Symptoms are significantly improved, and laboratory tests show improvement.

[0257] 3. Not cured: Symptoms and laboratory tests show no progress.

[0258] Clinical data

[0259] Treatment group: 35 patients with rheumatoid arthritis who were clearly diagnosed clinically, including 21 males and 14 females, with an average age of 42 years. The shortest medical history was 6 months and the longest was 12 years. Among them, 14 cases had simple joint pain and soreness, and 21 cases were accompanied by restricted joint flexion and extension and numbness. Control group: 32 patients with rheumatoid arthritis who were treated for comparison during the same period. The two groups were comparable in terms of gender, age, course of disease, etc. after statistical processing.

[0260] Treatment method: The present invention conducts comparative treatment on cases of rheumatoid arthritis. The treatment group uses the ointment prepared according to the traditional Chinese medicine composition method of the present invention in Example 3 for external application treatment, changing the dressing every day and applying for 24 hours. The control group selects Shangshi Zhitong Plaster for treatment, one plaster per day, so as to analyze the curative effect of the present invention. The result analysis is shown in Table 5.

[0261] Table 5: Therapeutic effect of the traditional Chinese medicine composition method of the present invention on rheumatoid arthritis

[0262] Total number of cases Cured Improved Not cured Total effective rate Treatment group 35 21 12 2 94.29％ Control group 32 6 9 17 46.88％

[0263] Total effective rate = (number of cured + improved) cases / total number of cases × 100%. The total effective rates of the two groups were significantly different after χ 2 test (P < 0.01).

[0264] Clinical efficacy observation of the present invention for tennis elbow (lateral epicondylitis of the humerus):

[0265] The diagnostic basis and efficacy evaluation criteria for tennis elbow are formulated according to the "Diagnostic and Therapeutic Criteria for Traditional Chinese Medicine Diseases" of the State Administration of Traditional Chinese Medicine.

[0266] Diagnostic basis for tennis elbow:

[0267] 1. It is more common in special types of work or occupations, such as bricklayers, tennis players or those with a history of elbow injury.

[0268] 2. Pain on the lateral side of the elbow, and the pain shows a continuous progressive development. The pain is aggravated when doing actions such as wringing clothes, sweeping the floor, pouring water with a kettle, etc. The forearm is often weak due to pain, the grip strength is weakened, and even the object held falls to the ground. The pain is significantly reduced or disappears during rest.

[0269] 3. Tenderness on the lateral side of the elbow, with obvious tenderness at the lateral epicondyle of the humerus. The tension test of the extensor muscles of the forearm is positive, and the resistance test of the extensor muscles is positive.

[0270] Efficacy evaluation of tennis elbow:

[0271] 1. Cured: The pain and tenderness disappear, there is no pain when holding an object, and the elbow joint moves freely.

[0272] 2. Improved: The pain is reduced and the elbow function is improved.

[0273] 3. Not healed: The symptoms show no improvement.

[0274] Clinical data

[0275] Treatment group: 56 patients with tennis elbow who were clearly diagnosed clinically, including 36 males and 20 females, with an average age of 38 years. The shortest medical history was 3 months and the longest was 3 years. The main manifestations of their condition were pain on the lateral side of the elbow, obvious tenderness, and limited movement. Control group: 39 patients with tennis elbow who were treated for comparison during the same period. The two groups were comparable in terms of gender, age, disease course, etc. after statistical processing.

[0276] Treatment method:

[0277] In this invention, comparative treatment was carried out on cases of tennis elbow. The treatment group used the ointment prepared according to the traditional Chinese medicine composition method of this invention in Example 3 for external application treatment, changing the dressing every day and applying for 24 hours. The control group selected Shiangshi Zhitong Plaster for treatment, applying one plaster every day for 24 hours, so as to analyze the curative effect of this invention. The result analysis is shown in Table 6.

[0278] Table 6: Therapeutic effect of the traditional Chinese medicine composition method of this invention on tennis elbow

[0279] Total number of cases Cured Improved Not cured Total effective rate Treatment group 56 49 7 0 100％ Control group 39 8 12 19 51.28％

[0280] Total effective rate = (number of cured + improved) cases / total number of cases × 100%, and there was a significant difference in the total effective rates between the two groups after χ 2 test (P < 0.01).

[0281] Analysis of the overall therapeutic effect of this invention on neck, shoulder, waist and leg pain

[0282] Clinical data

[0283] Treatment group: The inventor accumulated a total of 282 cases of neck, shoulder, waist and leg pain in clinical practice, including 62 cases of cervical spondylosis, 49 cases of scapulohumeral periarthritis, 42 cases of lumbar intervertebral disc herniation, 38 cases of lumbar muscle strain, 35 cases of rheumatoid arthritis, and 56 cases of tennis elbow. The control group had a total of 240 cases of neck, shoulder, waist and leg pain treated, including 51 cases of cervical spondylosis, 39 cases of scapulohumeral periarthritis, 48 cases of lumbar intervertebral disc herniation, 31 cases of lumbar muscle strain, 32 cases of rheumatoid arthritis, and 39 cases of tennis elbow. The two groups were comparable in terms of gender, age, disease course, etc. after statistical processing.

[0284] Treatment method: The treatment group used the ointment prepared according to the traditional Chinese medicine composition method of this invention in Example 3 for external application treatment. The control group selected Shiangshi Zhitong Plaster for treatment, applying one plaster every day for 24 hours, so as to analyze the curative effect of this invention. The result analysis is shown in Table 7.

[0285] Table 7: Overall therapeutic effect of the traditional Chinese medicine composition method of this invention on neck, shoulder, waist and leg pain

[0286] Total number of cases Cured Improved Not cured Total effective rate Treatment group 282 220 55 7 97.52％ Control group 240 50 73 117 51.25％

[0287] Total effective rate = (number of cured + improved cases) / total number of cases × 100%. There was a significant difference in the total effective rates between the two groups after X2 test (P < 0.01).

[0288] Clinical efficacy of the hot melt adhesive patch prepared in Example 9 of the present invention for neck, shoulder, waist and leg pain

[0289] Clinical data: The inventor has clinically observed and treated 350 patients from 2018 to the present, aged from 21 to 72 years old, including 50 patients with lumbar disc herniation, scapulohumeral periarthritis, cervical spondylosis, lumbar muscle strain, hyperosteogeny, rheumatoid arthritis, and tennis elbow respectively.

[0290] Treatment method: Apply the hot melt adhesive patch prepared in Example 9 to the affected area, and each patch can be applied for 3 days.

[0291] The diagnostic basis, efficacy criteria and efficacy evaluation are the same as those described above.

[0292] The treatment results are shown in Table 8:

[0293] Table 8: Clinical efficacy of the hot melt adhesive patch prepared in Example 9 of the present invention for neck, shoulder, waist and leg pain

[0294] Diseases Total number of cases Cured Improved Not cured Total effective rate Lumbar disc herniation 50 32 13 5 90.00％ Lumbar muscle strain 50 32 12 4 92.00％ Osteoarthritis 50 30 15 5 90.00％ Rheumatoid arthritis 50 25 15 6 88.00％ Cervical spondylosis 50 35 11 4 92.00％ Scapulohumeral periarthritis 50 40 10 0 100.00％ Tennis elbow 50 45 5 0 100.00％

[0295] Total effective rate = (number of cured + improved cases) / total number of cases × 100%.

[0296] Clinical efficacy of the far-infrared magnetic therapy patch prepared in Example 12 of the present invention for neck, shoulder, waist and leg pain

[0297] Clinical data: The inventor has clinically observed and treated 350 patients from 2018 to the present, aged from 23 to 68 years old, including 50 patients with lumbar disc herniation, scapulohumeral periarthritis, cervical spondylosis, lumbar muscle strain, hyperosteogeny, rheumatoid arthritis, and tennis elbow respectively.

[0298] Treatment method: Apply the far-infrared magnetic therapy patch prepared in Example 12 to the affected area, and each patch can be applied for 3 days.

[0299] The diagnostic basis, efficacy criteria and efficacy evaluation are the same as those described above.

[0300] The treatment results are shown in Table 9:

[0301] Table 9: Clinical efficacy of the far-infrared magnetic therapy patch prepared in Example 12 of the present invention for neck, shoulder, waist and leg pain

[0302] Diseases Total number of cases Cured Improved Not cured Total effective rate Lumbar disc herniation 50 29 16 5 90.00％ Lumbar muscle strain 50 45 5 0 100.00％ Osteoarthritis 50 28 17 5 90.00％ Rheumatoid arthritis 50 26 18 6 88.00％ Cervical spondylosis 50 33 12 5 90.00％ Scapulohumeral periarthritis 50 43 5 2 96.00％ Tennis elbow 50 46 4 0 100.00％

[0303] Total effective rate = (number of cured + improved cases) / total number of cases × 100%.

[0304] Typical cases:

[0305] 1. Xi, male, 49 years old, from Fusui County, Guangxi Zhuang Autonomous Region. Diagnosed by CT: Herniated discs at C4 and C5. The ointment prepared according to Example 3 of the present invention was applied externally, with the dressing changed once a day. After 15 days, the patient was cured, the original symptoms disappeared, the functions of the neck and limbs returned to normal, and the patient was able to resume normal work.

[0306] 2. Chen, female, 55 years old, from Taishun County, Zhejiang Province. Suffered from scapulohumeral periarthritis for up to 2 years. The pain in the right shoulder radiated to the right neck, back and elbow, and the pain was aggravated by movement. The patient felt obvious pain when combing hair, dressing or washing face. The ointment prepared according to Example 3 of the present invention was applied externally. After 8 days, the shoulder pain disappeared and the function recovered.

[0307] 3. Ye, male, 37 years old, from Lishui District, Foshan City, Guangdong Province. Diagnosed by CT: Osteophytes at the edges of L3-5 and S1 vertebral bodies, bulging and herniation (central type) of the discs at L4 / L5 and L5 / S1, lumbar spinal degenerative changes. Treated in many hospitals without effect, the condition worsened, with pain day and night, numbness and twitching pain in the left leg, and difficulty walking. The ointment prepared according to Example 3 of the present invention was applied externally, with the dressing changed once a day. After 21 days, the patient was cured, the low back and leg pain disappeared, and the patient was able to resume the original work.

[0308] 4. Lai, male, 46 years old, from Liwan District, Guangzhou City. The X-ray anteroposterior cervical spine radiograph showed a straightening of the cervical spine physiological curvature, a slight narrowing of the intervertebral space, and mild osteophytes of the vertebral bodies. The patient had stabbing pain in the neck and shoulders, the pain was fixed at the painful area, accompanied by limb numbness. The hot melt adhesive patch prepared according to Example 9 of the present invention was applied. After 15 days, the patient was cured, the original symptoms disappeared, and the patient was able to participate in normal work and labor.

[0309] 5. Zhou, female, 73 years old, from Li District, Jiangjin City, Chongqing. Suffered from scapulohumeral periarthritis for more than 2 years. There was obvious tenderness in the subacromial bursa, and the movement of the shoulder joint was limited in all directions. The hot melt adhesive patch prepared according to Example 9 of the present invention was applied externally. After 7 days, the patient was cured, the shoulder pain disappeared, and the function of the shoulder joint was completely restored.

[0310] 6. Xian, female, 53 years old, from Huangpo, Wuchuan City, Zhanjiang City, Guangdong Province. Suffered from scapulohumeral periarthritis for 6 months. There was pain in the shoulder and around, which was aggravated at night, and the movement function of the shoulder joint was impaired. The hot melt adhesive patch prepared according to Example 9 of the present invention was applied. After 6 days, the shoulder pain disappeared and the shoulder joint could move freely.

[0311] 7. Liu, female, 49 years old, from Hengnan County, Hunan Province. CT diagnosis showed bulging and posterior herniation (central type) of the discs at L4 / L5 and L5 / S1; lumbar spinal degenerative changes. The patient's low back pain radiated to the buttocks and lower limbs, and the pain was aggravated by coughing and sneezing. The hot melt adhesive patch prepared according to Example 9 of the present invention was applied. After 16 days, the patient was cured and the original symptoms disappeared.

[0312] 8. Deng, female, 54 years old, from Wusheng County, Sichuan Province. Suffering from lumbar disc bulge. CT diagnosis: Bulge of L4 / 5 intervertebral disc, osteoproliferation at the edge of L4-5 vertebral body. The patient had abnormal skin sensation on the anterolateral part of the lower leg, the anteromedial part of the dorsum of the foot and the sole. After applying the hot melt adhesive patch made according to Example 9 of the present invention for 23 days, the patient was cured and the original symptoms disappeared.

[0313] 9. Zhang, male, 54 years old, from Guangshan County, Henan Province. Suffering from lumbar muscle strain, with pain in the waist like a stabbing pain, fixed in location, and sometimes the pain was so severe that he couldn't turn over. After applying the hot melt adhesive patch made according to Example 9 of the present invention for 5 days, the patient was cured, the original symptoms disappeared, and the waist could move freely.

[0314] 10. Chen, female, 58 years old, from Yuexiu District, Guangzhou City, Guangdong Province. Suffering from rheumatoid arthritis. After applying the hot melt adhesive patch made according to Example 9 of the present invention for 12 days, the patient was cured, the joint pain and numbness disappeared, and the joint movement was normal.

[0315] 11. Yang, male, 56 years old, from Long'an County, Guangxi Zhuang Autonomous Region. A factory carpenter, suffering from tennis elbow, with soreness and numbness in the elbow, difficult flexion and extension, and the condition aggravated by cold. The disease course was more than 8 months. After applying the hot melt adhesive patch made according to Example 9 of the present invention for 10 days, the patient was cured, the original pain and numbness disappeared, and the elbow could move freely.

[0316] 12. Wu, female, 43 years old, from Yilong County, Sichuan Province. Suffering from cervical spondylosis, with neck pain accompanied by radiating pain in the upper limb, which was aggravated when the neck was extended backward, and the skin segment distribution area of the compressed nerve root had weakened sensation, and the neck movement was limited. After applying the far-infrared magnetic therapy patch made according to Example 12 of the present invention for 15 days, the patient was cured and the original symptoms disappeared.

[0317] 13. Zhu, male, 52 years old, from Nantian, Lechang City, Guangdong Province. Suffering from scapulohumeral periarthritis for 1 year, with extensive tenderness on the outside, front and back of the affected shoulder. After applying the far-infrared magnetic therapy patch made according to Example 12 of the present invention for 7 days, the patient was cured, the shoulder pain disappeared, and the shoulder joint function was completely restored.

[0318] 14. Gong, male, 42 years old, from Jinxi County, Fuzhou City, Jiangxi Province. Suffering from lumbar disc herniation. CT diagnosis: The L5 / S1 intervertebral disc protruded backward and to the right, the L4 / 5 intervertebral disc protruded backward, and there was osteoproliferation in the L1-5 vertebral bodies. The patient had radiating pain in the waist, passing through the buttocks, the posterior side of the thigh, the lateral side of the lower leg to the outer ankle, and had difficulty walking. After applying the far-infrared magnetic therapy patch made according to Example 12 of the invention for 22 days, the patient was cured.

[0319] 15. Fu, male, 50 years old. From Taojiang County, Yiyang City, Hunan Province. Suffering from lumbar muscle strain, with repeated attacks over more than 3 years, and soreness and discomfort in both sides of the lumbosacral region. After applying the far-infrared magnetic therapy patch made according to Example 12 of the present invention for 5 days, the low back pain symptoms disappeared and the waist could move freely.

[0320] 16. Liang, male, 57 years old, from Yuntan District, Gaozhou City, Guangdong Province. He had osteoproliferation of the intercondylar eminence of the left tibia. After applying the far-infrared magnetic therapy patch prepared according to Example 12 of the present invention for 18 days, he was cured, the pain and numbness in the lower limbs disappeared, and he could walk freely.

[0321] 17. Yang, female, 57 years old, from Dong'an County, Hunan Province. She suffered from rheumatoid arthritis. For more than 3 years, her right knee joint often ached, was numb, and had limited movement. After applying the far-infrared magnetic therapy patch prepared according to Example 12 of the present invention for 16 days, she was cured, the original symptoms disappeared, and her right knee could move freely. 18. Chen, male, 52 years old, from Tongliang District, Chongqing City. He had tennis elbow. After applying the far-infrared magnetic therapy patch prepared according to Example 12 of the present invention for 10 days, he was cured, the pain and tenderness disappeared, there was no pain when holding objects, and his elbow could move freely. BRIEF DESCRIPTION OF THE DRAWINGS

[0322] Figure 1 It is: Table 1 The therapeutic effect of the traditional Chinese medicine composition method of the present invention on cervical spondylosis Figure 2 It is: Table 2 The therapeutic effect of the traditional Chinese medicine composition method of the present invention on scapulohumeral periarthritis Figure 3 It is: Table 3 The therapeutic effect of the traditional Chinese medicine composition method of the present invention on lumbar intervertebral disc herniation Figure 4 It is: Table 4 The therapeutic effect of the traditional Chinese medicine composition method of the present invention on lumbar muscle strain Figure 5 It is: Table 5 The therapeutic effect of the traditional Chinese medicine composition method of the present invention on rheumatoid arthritis Figure 6 It is: Table 6 The therapeutic effect of the traditional Chinese medicine composition method of the present invention on tennis elbow Figure 7 It is: Table 7 The overall therapeutic effect of the traditional Chinese medicine composition method of the present invention on neck, shoulder, waist and leg pain Figure 8 It is: Table 8 The clinical efficacy of the hot melt adhesive patch prepared in Example 9 of the present invention on neck, shoulder, waist and leg pain Figure 9 It is: Table 9 The clinical efficacy of the far-infrared magnetic therapy patch prepared in Example 12 of the present invention on neck, shoulder, waist and leg pain.

Claims

1. A Chinese medicine composition and preparation method for treating lumbar disc herniation and shoulder, neck, waist and leg pain, characterized in that the following, It is composed of the following raw materials in parts by weight: 35-96 parts of rhubarb, 28-90 parts of clematis, 33-77 parts of golden cockscomb, 35-85 parts of siler, 35-96 parts of angelica, 33-77 parts of mulberry leaves, 35-95 parts of curculigo, 28-90 parts of peach kernel, 33-77 parts of agrimony, 40-96 parts of cynanchum, 32-92 parts of epimedium, 35-95 parts of frankincense, 35-85 parts of fishing rods, 32-92 parts of safflower, 35-96 parts of cibotium barometz, 33-77 parts of phoenix tail grass, 32-92 parts of myrrh, 35-96 parts of cyathula, 35-95 parts of angelica dahurica, and 28-90 parts of earthworms.

2. The Chinese medicine composition and preparation method for treating lumbar disc herniation and shoulder, neck, waist and leg pain according to claim 1, characterized in that the following, It is composed of the following raw materials in parts by weight: 70 parts of rhubarb, 70 parts of clematis, 70 parts of golden cockscomb, 70 parts of siler, 70 parts of angelica, 70 parts of mulberry leaves, 70 parts of curculigo, 70 parts of peach kernel, 70 parts of agrimony, 70 parts of cynanchum, 70 parts of epimedium, 70 parts of frankincense, 70 parts of fishing rods, 70 parts of safflower, 70 parts of cibotium barometz, 70 parts of phoenix tail grass, 70 parts of myrrh, 70 parts of cyathula, 70 parts of angelica dahurica, 70 parts of earthworms.

3. The Chinese medicine composition and preparation method for treating lumbar disc herniation and shoulder, neck, waist and leg pain according to claim 1, characterized in that the following, It is composed of the following raw materials in parts by weight: 45 parts of rhubarb, 45 parts of clematis, 45 parts of golden cockscomb, 90 parts of siler, 45 parts of angelica, 45 parts of mulberry leaves, 45 parts of curculigo, 45 parts of peach kernel, 45 parts of agrimony, 45 parts of cynanchum, 45 parts of epimedium, 90 parts of frankincense, 45 parts of fishing rods, 90 parts of safflower, 45 parts of cibotium barometz, 45 parts of phoenix tail grass, 45 parts of myrrh, 45 parts of cyathula, 90 parts of angelica dahurica, 45 parts of earthworms.

4. The Chinese medicine composition and preparation method for treating lumbar disc herniation and shoulder, neck, waist and leg pain according to claim 1, characterized in that the following, It is composed of the following raw materials in parts by weight: 90 parts of rhubarb, 49 parts of clematis, 49 parts of golden cockscomb, 90 parts of siler, 49 parts of angelica, 49 parts of mulberry leaves, 49 parts of curculigo, 49 parts of peach kernel, 49 parts of agrimony, 49 parts of cynanchum, 49 parts of epimedium, 49 parts of frankincense, 49 parts of fishing rods, 90 parts of safflower, 90 parts of cibotium barometz, 49 parts of phoenix tail grass, 49 parts of myrrh, 90 parts of cyathula, 90 parts of angelica dahurica, 49 parts of earthworm.

5. The method for preparing a Chinese medicine according to any one of claims 1 to 4, characterized in that: The Chinese medicine composition method is prepared into ointment, cream, plaster, patch, plaster, gel, wine, tincture, aerosol, spray and film.

6. The method for preparing a Chinese medicine according to any one of claims 1 to 4, characterized in that: The traditional Chinese medicine composition method is used to prepare rubber plaster, gel plaster, hot melt adhesive plaster and far infrared magnetic therapy patch. The composition and preparation method of Chinese medicine for external use for treating lumbar disc herniation and shoulder, neck, waist and leg pain are characterized by: grinding rhubarb, cyperus rotundus, golden cocktail, saposhnikovia divaricata, angelica sinensis, mulberry leaf, curculigo, peach kernel, agrimony, Cynanchum longituba, epimedium, frankincense, fishing rod, safflower, Cibotium barometz, phoenix tail grass, myrrh, Cyathula officinalis, Angelica dahurica, and earthworm into coarse powder, mixing evenly, percolating with 50-90% ethanol, percolating and concentrating into extract, or refluxing with 50-90% ethanol for 1-3 times, each time for 0.5-2 hours, extracting and concentrating into extract. It is made into hot melt adhesive patch, far infrared magnetic therapy patch, rubber patch, gel patch, ointment, cream, gel, tincture, aerosol, spray or film.

7. The Chinese medicine composition and preparation method for external use for treating lumbar disc herniation and shoulder, neck, waist and leg pain according to claim 7, characterized in that: Percolate with 55-85% ethanol; or reflux extract with 55-85% ethanol 2-3 times, each time for 0.5-1.5 hours.

8. The Chinese medicine composition and preparation method for external use for treating lumbar disc herniation and shoulder, neck, waist and leg pain according to claim 7, characterized in that: Cut rhubarb, cyperus rotundus, golden cocktail, saposhnikovia divaricata, angelica sinensis, mulberry leaves, curculigo orchioides, peach kernel, agrimony, cyperus rotundus, epimedium, frankincense, fishing rod, safflower, dog spine, phoenix tail grass, myrrh, cyathula capitata, angelica dahurica, earthworm into sections or pieces, and soak them in edible sesame oil for 36 hours. (1) Extraction of medicinal materials (boil until dry and remove residue); heat the sesame oil and soaked medicinal materials in the pot and stir continuously until the surface of the medicinal materials is fried to dark brown and the inside is brown. At this time, the temperature can reach 220℃. After frying, use a wire sieve to remove the medicinal residue. The oil after removing the residue is the medicinal oil. (2) Refining oil; remove the above medicinal oil and continue to boil. When the oil temperature rises to a certain level and reaches 320℃, use medium heat. The temperature of oil refining: First, look at the thermometer to see if it reaches the specified temperature; second, look at the oil smoke, which starts out as light green, gradually turns black and thick, and then turns into thick white smoke. When there is no wind, the white smoke is the most prominent; third, look at the oil flowers. When boiling begins, the oil flowers are mostly around the pot wall. When the oil flowers gather towards the center of the pot, it is the right temperature; fourth, water drops into beads. Take a small amount of medicinal oil and drop it into the water. If it does not disperse into beads, it is the right temperature (this level is the most difficult. You must refine the oil until the water drops into beads. You must pay attention to the temperature. The temperature cannot be too high) (3) Add the elixir to make a paste; after the medicinal oil is refined, remove the fire and add the elixir. Under normal circumstances, 500 grams of medicinal oil can be added with about 250 grams of yellow elixir. Before adding the yellow elixir, dry it and sieve it with a 100-mesh sieve. Add the elixir in small amounts gradually, stirring while adding, and stirring in the same direction. Stir it into a viscous paste. The plaster should not stick to your hands and it should be good if it can be drawn continuously. If it is too hard, it is old, and if it is too sticky, it is tender. (4) Remove fire poison; after the plaster is made, soak it in cold water, change the water once a day, and it will become a plaster in seven days. Spread the ointment on cotton cloth, and the ointment is ready. (5) Grind rhubarb, clematis, golden cocktail, saposhnikovia, angelica, mulberry leaves, curculigo, peach kernel, agrimony, Cynanchum, epimedium, frankincense, fishing rod, safflower, dog spine, phoenix tail grass, myrrh, Sichuan cyathula, angelica, and earthworm into coarse powder and make a wine solution.

9. According to claims 1 to 4, the composition and preparation method of Chinese medicine for external use for treating lumbar disc herniation and shoulder, neck, waist and leg pain, characterized in that: Rhubarb, clematis, cockscomb, siler, angelica, mulberry leaf, curculigo, peach kernel, agrimony, cynanchum, epimedium, frankincense, fishing rod, safflower, cibotium barometz, phoenix tail grass, myrrh, cyathula capitata, angelica dahurica and earthworm are ground into fine powder with a particle size of 120-200 μm, or the obtained fine powder is further crushed into ultrafine powder with a particle size of 0.1-50 μm in an ultrafine grinding device to make a hot melt adhesive patch, far-infrared magnetic therapy patch, ointment or cream.

10. The Chinese medicine composition and preparation method for treating lumbar disc herniation and shoulder, neck, waist and leg pain according to claim 1 are used in medicines of the Chinese medicine composition for treating lumbar disc herniation, scapulohumeral periarthritis, cervical spondylosis, lumbar muscle strain, bone hyperplasia, rheumatoid arthritis and tennis elbow.

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