Multi-project urine analysis strip combined product as well as use method, manufacturing method and production line thereof

Abstract

The invention provides a multi-project urine analysis strip combined product as well as a use method, a manufacturing method and a production line thereof. The multi-item urine analysis strip combined product comprises a first multi-item urine analysis strip and a second multi-item urine analysis strip, the first multi-item urine analysis strip and the second multi-item urine analysis strip are connected through an intersection part, and the intersection part comprises a disconnectable parting line. The multi-item urine analysis strip is formed by an upper cover layer and a space manufacturing layer in a surrounding mode, and the upper cover layer and the space manufacturing layer are connected in a sealed mode through a first bonding layer to form a cavity. The cavity comprises a first platform provided with multi-item urine analysis test paper, a urine inlet corresponding to the first platform, a second platform provided with an absorption pad and an inclined plane used for urine conduction, the first platform and the second platform are arranged at an interval through the inclined plane, and the horizontal height of the first platform is larger than that of the second platform during use. The production line is high in automation degree, adopts coiled materials for production, and is suitable for mass production and processing.

Description

Technical Field

[0001] The present invention relates to the fields of in vitro diagnosis and medical devices, and particularly to a multi-item urine analysis strip combination product and a method for using the same, as well as a method and a production line for manufacturing the multi-item urine analysis strip combination product. Background Art

[0003] In the prior art, urine analysis test strips are generally made by soaking high-quality filter paper in a prepared chemical reagent, then drying, cutting into blocks, and pasting them onto a plastic strip in a certain order and at a certain interval. When in use, the urine analysis test strip is immersed in freshly stirred urine, and then taken out in time. The test strip is leaned against the edge of the container to drip out the excess urine or placed on a tissue to absorb the excess liquid, and then the result is measured. The result measurement methods of urine analysis test strips include visual inspection and machine measurement. The visual inspection method is to compare the color development result of the test strip infiltrated with urine after a period of time with a standard colorimetric card to obtain the result. The machine measurement method is to place the test strip infiltrated with urine into a portable multi-item urine analyzer disclosed in utility model patents such as CN207020187U and CN207066995U. The analyzer collects and compares the color development result of the test strip and obtains the result, reducing the error of visual comparison. However, up to now, there are still urine contamination problems in the use of urine analysis test strips, including human contamination and analyzer contamination. Because the urine-soaked test strip is completely exposed to the external environment after being infiltrated with urine, the operator must be extremely careful to use a tissue to absorb the excess urine to prevent urine contamination, that is, it may contaminate the operator's hand with urine, and urine will also remain in the analyzer, which is not convenient for ordinary family members to use.

[0004] With the development of electronic products, urine detection devices convenient for home use have been designed, such as those disclosed in invention patents CN105866116B and CN109387618B. Although these urine detection devices can be directly rinsed after the detection to prevent urine residue, the problem of human contamination has not been completely solved. While increasing the R & D and manufacturing costs of the analyzer, it also adds the cleaning step and introduces the risk of water-related failures of the analyzer.

[0005] In addition, existing urine analysis test strips are basically single-person packaging or bucket packaging. The single-person packaging has a high cost, while the bucket packaging is prone to inversion and moisture absorption of the urine analysis test strip, affecting the test result. Summary of the Invention

[0006] In order to solve the above problems, the present invention provides a multi-item urine analysis strip combination product, a method for using the same, a manufacturing method, and a production line.

[0007] A multi - item urine analysis strip combination product includes a first multi - item urine analysis strip and a second multi - item urine analysis strip. The first multi - item urine analysis strip and the second multi - item urine analysis strip are connected by an intersection part, and the intersection part includes a breakable dividing line. Moreover, the multi - item urine analysis strip is formed by enclosing an upper cover layer and a space - making layer. The upper cover layer and the space - making layer are hermetically connected through a first bonding layer and form a cavity. The first bonding layer can be an adhesive material or a fusion line. The cavity includes a first platform configured with a multi - item urine analysis test strip, a urine inlet corresponding to the first platform, a second platform configured with an absorption pad, and an inclined plane for urine conduction. The first platform and the second platform are spaced apart by the inclined plane. After urine is added from the urine inlet, the horizontal height of the first platform is greater than that of the second platform, and urine flows from the first platform along the inclined plane to the second platform and is absorbed by the absorption pad.

[0008] Furthermore, the width of the upper cover layer is greater than or equal to the width of the space - making layer, and an extension part is formed above the upper cover layer. The intersection part is located in the extension part. Thus, the intersection part is thinner, which is conducive to separating the multi - item urine analysis strip through the dividing line.

[0009] Furthermore, a sealing film is configured on the upper cover layer. The sealing film and the upper cover layer are connected through a second bonding layer, and the second bonding layer can be an adhesive material or a non - adhesive material.

[0010] Furthermore, the width of the sealing film is greater than the width of the upper cover layer, and the intersection part is located in the extension part of the sealing film. Preferably, at least two second platforms are respectively arranged on both sides of the first platform in the cavity. In this case, two absorption pads can be set, which can ensure that excess urine is fully and completely absorbed.

[0011] Furthermore, the multi - item urine analysis test strip and the absorption pad form a composite card with a common bottom plate, and the composite card fits tightly with the bottom of the cavity.

[0012] Furthermore, the composite card is bonded to the bottom of the cavity through a third bonding layer, and the third bonding layer is an adhesive material. A manufacturing method of a multi - item urine analysis strip combination product includes the following steps:

[0013] S1, Obtain a space - making layer and an upper cover layer. The space - making layer includes a first platform, a second platform and an inclined plane, as well as an inclined plane connecting the first platform and the second platform. The upper cover layer includes an intersection part with a breakable dividing line. S2, Prepare a large test item card in sequence, cut to obtain a single test item small card, paste multiple single test item small cards onto a bottom card, and then cut to obtain a multi - item urine analysis test strip.

[0014] S3, Cut a large absorption pad card to obtain an absorption pad.

[0015] S4. Paste the multi - item urine analysis test strip and the absorbent pad onto the first platform and the second platform.

[0016] S5. Seal and connect the upper cover layer and the space - manufacturing layer through the first adhesive layer to form a cavity.

[0017] Furthermore, in step S1, the step of obtaining the space - manufacturing layer is as follows: heat the coil material and face it towards the opening of the mold, move the mold and evacuate air through the air holes at the bottom of the mold to form the space - manufacturing layer, and then cut to obtain a single space - manufacturing layer.

[0018] Furthermore, rotate and invert the space - manufacturing layer before step S5.

[0019] Furthermore, during the process of rotating and inverting the space - manufacturing layer, check the firmness of the adhesion of the multi - item urine analysis test strip and the absorbent pad.

[0020] Furthermore, in step S5, a "0" - shaped fusion line is formed circumferentially at the connection part through a continuously heated sealing ring.

[0021] A production line for applying the manufacturing method of the above - mentioned multi - item urine analysis strip combination product includes a space - manufacturing component, a test - strip assembly component, an upper - cover sealing component, a transmission component, and a finished - product receiving component. The space - manufacturing component includes a first loading roller loaded with a flexible coil material, a heating bin for heating the flexible material, a mold for forming the space - manufacturing layer, a gas - extraction device, and a cutting device for obtaining a single space - manufacturing layer. The test - strip assembly component includes an adhesive head for outputting adhesive and a gripper for grasping the multi - item urine analysis test strip. The upper - cover sealing component includes a second loading roller loaded with a flexible upper - cover coil material and a sealing ring for heating to seal the space - manufacturing layer and the upper - cover layer. The transmission component includes a conveyor belt that runs through the space - manufacturing component, the test - strip assembly component, the sealing component, and the finished - product receiving component. This production line has a high degree of automation, uses coil materials for production, is suitable for mass production and processing, saves a large amount of labor costs, and meets the growing market demand for urine analysis products. Even further, the production line also includes a waste - inspection component located after the test - strip assembly component. The waste - inspection component is used to inspect the space - manufacturing layer loaded with the finished multi - item urine analysis test strip after rotation and inversion, and the waste - inspection component determines the firmness of the adhesion of the multi - item urine analysis test strip and the absorbent pad.

[0022] Furthermore, the production line also includes a splitting and packaging component located after the upper - cover sealing component. The splitting and packaging component splits and packages multi - item urine analysis strip combination products of different specifications.

[0023] A method for using the above - mentioned multi - item urine analysis strip combination product includes the following steps:

[0024] S1. Separate a single multi - item urine analysis strip through the separation line.

[0025] S2. Take a certain amount of urine and slowly and evenly pour the urine from the first end to the second end through the urine inlet so that the urine wets the multi - item urine analysis test strip.

[0026] S3. Wait for a certain period of time and obtain the test result by standard color comparison.

[0027] Furthermore, when in a static state, the horizontal height of the first platform is equal to or less than that of the second platform. After step S2, wait for a certain period of time, and pour the multi - item urine analysis strip at an angle equivalent to the angle α, so that the excess urine flows from the first platform to the second platform along the inclined plane and is absorbed by the absorbent pad.

[0028] Furthermore, before step S2, tear open the sealing film of the upper cover layer; before step S3, reseal the sealing film; in step S3, obtain the test result through the sealing film, and then discard the multi - item urine analysis strip in the sealed state.

[0029] The beneficial effects of the present invention include: 1. Improve user usability and convenient operation. There is no need for precise control of the urine volume. The operator no longer needs to risk getting their hands contaminated by urine and can easily and without burden complete all test steps, solving the pollution problem without bringing new problems. 2. Since the multi - item urine analysis strip has a simple structure, the production automation degree is high, and it can be produced using a roll material, which is suitable for large - batch production and processing, saving a large amount of labor costs and meeting the growing market demand for urine analysis products. 3. The combined product has strong adaptability to packaging specifications, does not require additional moisture - proof packaging, and saves packaging and transportation costs. 4. Whether it is a multi - item urine analysis test strip that only needs to leave the urine immediately after wetting or a test that needs to be fully immersed in urine and then leave the urine, it can be achieved in the multi - item urine analysis strip combined product of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 It is a schematic structural diagram of a multi - item urine analysis test strip.

[0031] Figure 2 It is one of the cross - sectional views of the multi - item urine analysis strip.

[0032] Figure 3 It is the second cross - sectional view of the multi - item urine analysis strip.

[0033] Figure 4 It is a schematic diagram of the production process of the multi - item urine analysis strip.

[0034] Figure 5 It is the third cross - sectional view of the multi - item urine analysis strip.

[0035] Figure 6One of the schematic diagrams of the multi - item urine analysis strip combination product.

[0036] Figure 7 One of the schematic diagrams of the intersection part of the multi - item urine analysis strip combination product.

[0037] Figure 8 One of the schematic diagrams of the multi - item urine analysis strip combination product.

[0038] Figure 9 One of the schematic diagrams of the intersection part of the multi - item urine analysis strip combination product.

[0039] Figure 10 One of the schematic diagrams of the multi - item urine analysis strip combination product.

[0040] Figure 11 Schematic diagram of the production line of the multi - item urine analysis strip combination product.

[0041] Figure 12 Exploded view of the multi - item urine analysis strip combination product. Embodiment

[0043] Example 1

[0044] As Figure 1 shown, the multi - item urine analysis test strip 10 is shown. The multi - item urine analysis test strip 10 is composed of a base card 101 and a test strip pad 102. The test strip pads 102 for multiple detection items are evenly spaced and pasted on the base card 101 in sequence. And the distance between the test strip pads 102 at both ends of the base card 101 from the edge of the base card 101 is equivalent to the uniform interval between the test strip pads. Here, "equivalent" means approximately equal to or equal to.

[0045] As Figure 2As shown in (a), a multi - item urine analysis strip is presented, which includes a cavity 11 and a multi - item urine analysis test strip 10. The cavity 11 contains a first platform 12 on which the multi - item urine analysis test strip 10 is loaded, and a second platform 13 on which an absorbent pad 65 is loaded. The width of the multi - item urine analysis test strip 10 is less than the width of the first platform 12, the width of the absorbent pad 65 is less than the width of the second platform 13, and the width of the multi - item urine analysis test strip 10 is less than the width of the absorbent pad 65. In the static state, the first platform 12 and the second platform 13 are at the same horizontal height, and they are connected together by an inclined plane 14. The second platform 13 is arranged on one side of the first platform 12, and the horizontal height of the first platform 12 is equal to the horizontal height of the second platform 13. Here, the comparison of the horizontal height is judged based on the horizontal height at the lowest points of the first platform 12 and the second platform 13. In the use state, urine is added from a urine inlet (not shown). The urine inlet is arranged corresponding to the first platform 12, so that urine enters the space where the first platform is located from the urine inlet. Then the urine wets the multi - item urine analysis test strip 10, including instantaneous wetting or sufficient wetting, that is, immediately or after waiting for a certain time, perform a pouring operation to make the horizontal height of the first platform 12 greater than the horizontal height of the second platform 13 to ensure that urine flows from the first platform 12 to the space where the second platform 13 is located and is completely absorbed by the absorbent pad in the second platform 13. The included angle α formed by the first platform 12 and the inclined plane 14 is less than 90°. This included angle can be set to any angle, but it is preferably greater than 90° but less than 360°. Since the waste liquid needs to be absorbed through the inclined plane 14 after urine is added to the multi - item urine analysis strip, if the included angle α is less than 90°, it is not conducive to the complete absorption of the waste liquid by pouring.

[0046] As shown in Figure 2 As shown in (b), a multi - item urine analysis strip is presented. The width of the multi - item urine analysis test strip 10 is less than the width of the first platform 12, the width of the absorbent pad 65 is less than the width of the second platform 13, and the width of the multi - item urine analysis test strip 10 is less than the width of the absorbent pad 65. The included angle α formed by the first platform 12 and the inclined plane 14 is greater than 90°.

[0047] As shown in Figure 2As shown in (c), a multi - item urine analysis strip is presented. When in a static state, the horizontal height of the first platform 12 is equal to that of the second platform 13. The width of the multi - item urine analysis test strip 10 is equal to the width of the first platform 12, which is equal to the width of the absorption pad 65 and is equal to the width of the second platform 13. The angle α formed by the first platform 12 and the inclined plane 14 is greater than 90°. Urine is added from the urine inlet (not shown). The urine inlet is correspondingly arranged relative to the first platform 12, so that urine enters the space where the first platform is located from the urine inlet. Then the urine wets the multi - item urine analysis test strip 10, including instantaneous wetting or sufficient wetting, that is, immediately or after waiting for a certain time, perform the pouring operation to make the horizontal height of the first platform 12 greater than that of the second platform 13 to ensure that urine flows from the first platform 12 to the space where the second platform 13 is located and is completely absorbed by the absorption pad in the second platform 13.

[0048] On the dorsal side of the cavity 11, that is, on the dorsal side of the first platform 12, the second platform 13, and the inclined plane 14 of the multi - item urine analysis strip, a groove space 16 will be formed. This groove space 16 is beneficial for users to hold and use or to be positioned in the detection instrument.

[0049] As Figure 3 As shown, a multi - item urine analysis strip is presented, including a first platform 12 loaded with a multi - item urine analysis test strip 10 and two second platforms 13 loaded with absorption pads 65. The width of the multi - item urine analysis test strip 10 is greater than the width of the first platform 12, and the width of the absorption pad 65 is equal to the width of the second platform 13. In a static state, the first platform 12 and the second platform 13 are arranged in a staggered manner at different horizontal heights and are spaced by an inclined plane 14. The second platforms 13 are respectively arranged on both sides of the first platform 12, and the horizontal height of the first platform 12 is greater than that of the second platform 13. When in use, without performing the pouring operation, urine is added from the urine inlet 19. The urine inlet 19 is correspondingly arranged relative to the first platform 12, so that urine enters the space where the first platform is located from the urine inlet. Then the urine instantaneously wets the multi - item urine analysis test strip 10 and immediately flows from the space where the first platform 12 is located to the space where the second platform 13 is located along the inclined plane 14. Since the horizontal height of the first platform 12 is greater than that of the second platform 13, the urine is finally completely absorbed by the absorption pad in the second platform 13.

[0050] The cavity 11 is enclosed by an upper cover layer 17 and a space - making layer 18. The space - making layer 18 is as Figure 12 shown. As Figure 3As shown in the figure, the overlapping part of the upper cover layer 17 and the space manufacturing layer 18 is the connecting part 171, and a urine inlet 19 is provided on the upper cover layer 17. And between the upper cover layer 17 and the space manufacturing layer 18, without the need for additional adhesive materials, through the characteristics of the materials themselves, a fusion line can be formed between the upper cover layer 17 and the space manufacturing layer 18 in a hot processing manner. Of course, an adhesive material can also be used to fixedly connect the upper cover layer 17 and the space manufacturing layer 18 together. Whether it is the fusion line or the adhesive material, a layer that connects the upper cover layer 17 and the space manufacturing layer 18 is formed between them. In order to introduce urine onto the multi-item urine analysis test strip 10 in a more concentrated manner, the urine inlet 19 has a diameter that gradually narrows in the direction towards the cavity 11. The urine inlet 19 has a first end 191 and a second end 192. When introducing urine from the urine inlet 19, the urine should be slowly and evenly poured from the first end 191 to the second end 192, so as to ensure that the test paper pads on the multi-item urine analysis test strip can all directly contact the urine and avoid mutual influence between different test paper pads. In order to save packaging costs, a sealing film 20 that completely seals the urine inlet 19 is configured at the urine inlet 19 on the top of the upper cover layer 17. When the sealing film 20 is present, there is no need to perform a sealed packaging on the multi-item urine analysis strip. When the sealing film 20 is present, the multi-item urine analysis strip needs to be sealed and packaged to prevent it from being exposed to the air. In a more optimal case, the sealing film 20 is made of a transparent material and can be reused. The sealing film 20 and the upper cover layer are adhered together through an adhesive material. That is to say, when introducing urine, the sealing film 20 is opened, and after the urine is introduced, the sealing film 20 can be re-sealed through the adhesive material, and then the test result can be observed through the transparent sealing film 20. In a more optimal case, the sealing film 20 has an opening end that protrudes from the upper cover layer 17, and the user can open or close the sealing film 20 by holding the opening end.

[0051] In some embodiments, in order to achieve rapid and accurate positioning of the multi-item urine analysis test strip 10 and the absorbent pad 65 during the production process, the multi-item urine analysis test strip 10 and the absorbent pad 65 have a common bottom plate 63. That is to say, the multi-item urine analysis test strip 10 and the absorbent pad 65 are pasted on the common bottom plate 63 at a certain distance via an adhesive material to form a composite card 631. The spaced distance is the same as the width of the inclined surface 14, and the width of the inclined surface is the length of the path for urine to flow from the first platform to the second platform. The composite card 631 closely adheres to the plane formed by the first platform 12, the inclined surface 14, and the second platform 13, and fills the bottom 181 of the cavity. The first platform 12 is opposite to the part of the common bottom plate 63 where the multi-item urine analysis test strip 10 is pasted, the second platform 13 is opposite to the part of the common bottom plate 63 where the absorbent pad 65 is pasted, and the inclined surface 14 is opposite to the spaced part of the common bottom plate 63. As Figure 4As shown in the figure, it is the production process of a multi - item urine analysis strip. For each test item, a large card 61 of the test item is made respectively, and then the large card 61 is cut to obtain small cards 62; the small cards 62 of different test items are pasted onto the bottom card 101 at a certain interval, and then cut to obtain the finished multi - item urine analysis test paper 10. There are test paper pads 102 of different test items distributed on it. The certain interval is used to prevent interference between different items. The size of the interval is generally set to 2 - 4 mm. Of course, the certain interval can also be designed according to the characteristics of the test items; the large card 64 of the absorbent pad is cut to obtain the finished absorbent pad 65, and then the multi - item urine analysis test paper 10 and the absorbent pad 65 are pasted onto the common bottom plate 63 at a certain interval to obtain a composite card 631; the composite card 631 is installed at the bottom of the cavity. The common bottom plate 63 is a flexible bottom plate, which can change accordingly according to the shape of the bottom of the cavity to ensure that the composite card 631 fits closely with the bottom of the cavity, that is, fits closely with the plane formed by the first platform 12, the inclined surface 14, and the second platform 13; finally, the space manufacturing layer 18 and the upper cover layer 17 are fixed together to obtain the multi - item urine analysis strip. In most cases, the width of the multi - item urine analysis strip is less than or equal to 1.5 cm, the height is less than or equal to 0.5 cm, and the length is determined according to the number of multi - item urine analysis test papers.

[0052] In some other embodiments, in order to make the composite card fit more closely with the bottom of the cavity, an adhesive layer 632 is used to bond the composite card to the bottom of the cavity, that is, to bond it to the plane formed by the first platform, the inclined surface, and the second platform. The adhesive layer is formed by an adhesive material.

[0053] Example 2

[0054] As Figure 5 (a) shows that in a multi - item urine analysis strip with 1 first platform 12 and 2 second platforms 13, in the use state, after the first pouring, the horizontal height of one of the second platforms 131 is greater than the horizontal height of the first platform 12, and the horizontal height of the other second platform 132 is less than the horizontal height of the first platform 12. If the amount of urine absorbed by the absorbent pad on the second platform 132 reaches the limit and there is still remaining urine unabsorbed, then rotate by twice the angle of the first pouring to complete the second pouring, so that the horizontal height of the second platform 132 is greater than the horizontal height of the first platform 12, and the horizontal height of the second platform 131 is less than the horizontal height of the first platform 12, to complete the absorption of the remaining urine.

[0055] As Figure 5 (b) shows that in a multi - item urine analysis strip with 1 first platform 12 and 2 second platforms 13, in the use state, the horizontal height of one of the second platforms 131 is less than the horizontal height of the other second platform 132 which is less than the horizontal height of the first platform 12.

[0056] In the above two cases, the comparison of the horizontal height is determined by the horizontal height at the lowest points of the first platform 12 and the second platform 13. As Figure 5 (c) shows, the multi-item urine analysis strip can also be placed in a stationary state, and the horizontal heights between the first platform 12 and the second platform 13 are equal.

[0057] Example 3

[0058] A multi-item urine analysis strip combination product, as Figure 6 shown, includes at least two multi-item urine analysis strips in Example 1 or Example 2. The two multi-item urine analysis strips are connected by an intersection part 21. The intersection part 21 includes a breakable dividing line 211, as Figure 7 shown. The dividing line 211 is composed of a first edge line 171, a second edge line 172, and an intersection line 173 where the two extend and intersect. An included angle θ is formed between the first edge line 171 and the second edge line 172. Preferably, the included angle θ is less than 90°. In this way, the first edge line 171 and the second edge line 172 are easier to process and form, and it is also more convenient for users to tear and break the dividing line 211 through the included angle θ. Due to the existence of the dividing line and the characteristic that the multi-item urine analysis strip of the present invention does not require additional moisture-proof packaging, it is possible to quickly achieve any specification packaging. The number of multi-item urine analysis strips in the produced combination product is huge. When packaging, various specification packaging shares can be directly intercepted from the huge number of connected multi-item urine analysis strips. For example, one-pack, ten-pack, and fifty-pack can be quickly obtained. The intersection part 21 can be only located at the extended part 174 of the upper cover layer 17 of the two multi-item urine analysis strips, as Figure 8 and Figure 9 shown; it can also be only located at the extended part 174 of the sealing film 20 of the two multi-item urine analysis strips; or it is located at the extended parts 174 of both the upper cover layer 17 and the sealing film 20 of the two multi-item urine analysis strips at the same time. Since the sealing film 20 is located on the upper cover layer 17, the intersection part 21 is considered to be located above the upper cover layer 17 as a whole. When the intersection part 21 is only located at the extended part 174 of the sealing film 20, the width of the sealing film 20 is greater than the width of the upper cover layer 17. In this way, the length of the gap left between the upper cover layers 17 of any two multi-item urine analysis strips is greater than twice the thickness of the upper cover layer 17, preventing the extrusion force from being generated between the upper cover layers 17 and facilitating the separation of the two multi-item urine analysis strips by the user through the dividing line 211. The vertical distance L between the intersection line 173 and the first edge line 171 or the second edge line 172 is greater than or equal to half of the thickness d of the extended part 174, that is, L≥1 / 2d. As Figure 10As shown, in order to enable users to more conveniently separate any two multi-item urine analysis strips by the dividing line 211, a notch 175 can be provided at the end of the dividing line 211. In other embodiments, the dividing line 211 can also be a dotted line 176, that is, the dividing line 211 has through holes spaced apart and penetrating the thickness of the sealing film 20 or the upper cover layer 17. As Figure 12 shown, an exploded view of a multi-item urine analysis strip combination product shows one of the multi-item urine analysis strip combination products, in which the adhesive material is omitted.

[0059] Example 4

[0060] To manufacture the multi-item urine analysis strip combination product in Example 3, it is first necessary to obtain the space manufacturing layer 18 and the upper cover layer 17. The space manufacturing layer 18 and the upper cover layer 17 can be processed and manufactured separately or made on the unified production line of the combination product. Generally, the space manufacturing layer 18 can be manufactured by processes such as injection molding and blow molding using at least one of the materials such as PE, PP, PET, PVC, and LDPE. These materials can be made into flexible rolls, and the processed space manufacturing layer 18 includes the first platform 12, the second platform 13, and the inclined surface 14. The upper cover layer 17 can be processed and manufactured separately or made on the unified production line of the combination product. A sealing film 20 can also be configured on the top of the upper cover layer 17. The upper cover layer 17 or the sealing film 20 is a flexible roll, and each upper cover layer 17 or sealing film 20 can be disconnected through the dividing line 211 to form a set of flexible rolls.

[0061] As Figure 11As shown in the figure, the multi-project urine analysis strip combination product production line includes a space manufacturing component, a test strip assembly component, an upper cover sealing component, a transmission component, and a finished product receiving component. The space manufacturing component includes a first feeding roller 801, a feeding clamp 802, a heating bin 803, a mold 804, an air extraction device 805, and a cutting device 806. The first feeding roller 801 and the feeding clamp 802 cooperate with each other to complete the feeding of the flexible coil. A flexible coil for manufacturing the space manufacturing layer 18 is sleeved on the first feeding roller 801. The flexible coil passes through the heating bin 803 and is clamped by the feeding clamp 802. The flexible coil in the heating bin 803 is heated into a plasticizable form. The shape of the mold 804 is the same as that of the space manufacturing layer 18. It is arranged between the first feeding roller 801 and the feeding clamp 802. The mold opening 8041 faces the heated flexible coil. Air holes 8043 are provided at the bottom 8042 of the mold. When the heated flexible coil quickly reaches the position corresponding to the mold opening 8041 under the interaction of the first feeding roller 801 and the feeding clamp 802, the mold 804 is moved towards the heated flexible coil. The air extraction device 805 extracts air outward through the air holes 8043, and the heated flexible coil is formed in the mold 804 to obtain the space manufacturing layer 18. The first feeding roller 801 and the feeding clamp 802 cooperate with each other to move the heated flexible coil in the heating bin 803 towards the position corresponding to the mold opening 8041. At the same time, the formed space manufacturing layer 18, since it is still connected to the flexible coil, also moves towards the transmission component under the action of inertia. The transmission component only includes a first conveyor belt 807, or includes a first conveyor belt 807, a second conveyor belt 813, and an adsorption device (not shown). The conveyor belt runs through the space manufacturing component, the test strip assembly component, the upper cover sealing component, and the finished product receiving component. In one case, when the space manufacturing layer 18 contacts the first conveyor belt 807, the adsorption device thereon will firmly adsorb the space manufacturing layer 18 on the first conveyor belt 807. In another case, the space manufacturing layer is placed on the first conveyor belt, and there is no adsorption device to adsorb it. The cutting device 806 is arranged on the movement path of the first conveyor belt to cut off the connected part of the space manufacturing layer 18, so as to obtain a single space manufacturing layer 18.

[0062] To manufacture the multi - item urine analysis strip combination product in Manufacturing Example 3, it is also necessary to prepare the multi - item urine analysis test strip 10 pads and the absorbent pad 65. Separate single - test - item large cards 61 are prepared, and each large card contains the reaction reagent for one test item. After cutting and drying the single - test - item large cards 61, single - test - item small cards 62 are obtained. According to the requirements of different products, multiple single - test - item small cards 62 are pasted onto the bottom card 101 at a certain interval to obtain the semi - finished multi - item urine analysis test strip. The certain interval is used to prevent interference between different items. The size of the interval is generally set to 2 - 4 mm. Of course, this certain interval can also be designed according to the characteristics of the test items. On the semi - finished multi - item urine analysis test strip, the longitudinal reaction reagents are the same, that is, the single - test - item small cards 62, and the transverse reaction reagents are different. After transverse cutting, the finished multi - item urine analysis test strip 10 is obtained, and test strip pads 102 for different test items are distributed thereon. The absorbent pad large card 64 is cut to obtain the finished absorbent pad 65. The absorbent pad 65 can be blotting paper, which is used to absorb excess urine. However, better materials are those with physical adsorption and drying effects, such as silica gel, alumina gel, molecular sieve, activated carbon, bone charcoal, charcoal, etc. The absorbent pad 65 made of these materials keeps the product dry in the cavity 11 on the one hand and absorbs excess urine during the detection process on the other hand.

[0063] To manufacture the multi - item urine analysis strip combination product in Manufacturing Example 3, it is necessary to paste the aforementioned multi - item urine analysis test strip 10 and the absorbent pad 65 onto the first platform 12 and the second platform 13. In one case, the multi - item urine analysis test strip 10 and the absorbent pad 65 are pasted separately, and an adhesive material is used to paste between the urine analysis test strip and the first platform 12, and between the absorbent pad 65 and the second platform 13. In another case, when the multi - item urine analysis test strip 10 and the absorbent pad 65 have a common bottom plate 63 as described in Example 1, the multi - item urine analysis test strip 10 and the absorbent pad 65 are pasted together.

[0064] The test strip assembly component includes an adhesive head 808 and a gripper 809. When the space manufacturing layer 18 is transported to the test strip assembly component by a conveyor belt, the adhesive head 808 moves to the first platform 12 and the second platform 13 of the space manufacturing layer 18 respectively and outputs adhesive. The gripper 809 grabs the multi - item urine analysis test strip 10 and the absorbent pad 65 and places them onto the first platform 12 and the second platform 13 respectively. The multi - item urine analysis test strip 10 and the absorbent pad 65 are pasted onto the first platform 12 and the second platform 13 respectively through the adhesive.

[0065] To manufacture the multi - item urine analysis strip combination product in Manufacturing Example 3, it is necessary to fix the upper cover layer 17 and the space manufacturing layer 18 together.

[0066] The upper cover sealing assembly includes a second loading roller 810 and a sealing ring 811. The second loading roller 810 is loaded with a flexible upper cover layer coil, and can be continuously consumed as the second conveyor belt 813 moves. The flexible upper cover layer coil has been pre-cut with dividing lines, and this cutting step can be added to the production line of the present invention. After the test strip assembly is completed, the first conveyor belt 807 rotates and inverts the space manufacturing layer 18. After the rotation and inversion, the space manufacturing layer 18 just corresponds to the flattened upper cover layer 17 on the second conveyor belt 813. For the space manufacturing layer 18 that has corresponded to the upper cover layer 17, the adsorption device stops adsorption, and the space manufacturing layer 18 that has stopped being adsorbed detaches from the first conveyor belt 807 and moves on the second conveyor belt 813 together with the upper cover layer 17. The sealing ring 811 is arranged on the moving path of the second conveyor belt 813. The continuously heated sealing ring 811 moves and contacts the circumference of the connecting part 171 between the space manufacturing layer 18 and the upper cover layer 17. The sealing ring 811 applies force in the direction of the upper cover layer 17, tightly combines the circumference of the connecting part 171 between the space manufacturing layer 18 and the upper cover layer 17 together to form a "0"-shaped fusion line, so as to achieve the result of forming a sealed cavity 11, and obtain a multi-item urine analysis strip with sealing completed. It can be considered that the fusion line formed circumferentially at the connecting part between the upper cover layer 17 and the space manufacturing layer 18 is a kind of adhesive layer. The upper cover layer 17 and the space manufacturing layer 18 can also be sealed and connected with glue, or the upper cover layer 17 and the space manufacturing layer 18 can be sealed and connected by setting complementary structures on them, to obtain a multi-item urine analysis strip combination product, which is transmitted to the finished product receiving assembly 814 for temporary storage through the second conveyor belt 813. Finally, the multi-item urine analysis strip with sealing completed is conveyed by the second conveyor belt 813 to the finished product receiving assembly. In order to keep the dividing line 211 on the upper cover layer 17 or the sealing film 20, the sealing ring 811 also includes a notch 8111 to ensure that while sealing the connecting part 171 of the multi-item urine analysis strip, the dividing line 211 between the multi-item urine analysis strips is retained.

[0067] In some embodiments, in order to realize the rotation and inversion of the space manufacturing layer 18, the first conveyor belt 807 includes a set of inversion gears 8071. The number of inversion gears 8071 is at least 4, and the 4 gears are meshed and matched to ensure that the space manufacturing layer 18 smoothly changes to a position perpendicular to the horizontal plane during the operation of the first conveyor belt 807, and then changes to the position of vertical flipping before rotation and inversion.

[0068] In some embodiments, the finished product receiving assembly is replaced by a splitting and packaging assembly. The splitting and packaging assembly receives the multi-item urine analysis strip combination product and divides the multi-item urine analysis strip combination product into different packaging specifications according to the specifications preset by the computer through the dividing line 211 to complete packaging, such as one combination product having ten multi-item urine analysis strips, one combination product having fifty multi-item urine analysis strips, and so on.

[0069] In some embodiments, the adsorption device and the rotation and inversion device may not be provided, and the adhesive for connecting the upper cover layer and the space manufacturing layer is directly provided on the upper cover layer. When the space manufacturing layer on which the test strip assembly has been completed is facing upward, the upper cover layer is directly attached to the space manufacturing layer. This method requires strict control of the force used for attachment. Alternatively, while not providing the adsorption device and the rotation and inversion device, the second conveyor belt is also not provided. The flexible upper cover layer coil is arranged parallel to the first conveyor belt, and the upper cover layer and the space manufacturing layer are clamped and heat-sealed using an annular sealing device, and the multi-item urine analysis strip combination product is conveyed by the first conveyor belt. As Figure 11 shown, a waste inspection component is provided between the test strip assembly component and the upper cover sealing component. The waste inspection component includes an inspection lamp 812 and a waste bin 813, and is used to inspect and determine whether the multi-item urine analysis test strips 10 and the absorbent pad 65 pasted and loaded therein are firm when the space manufacturing layer 18 loaded with the finished multi-item urine analysis test strips 10 is in a vertical position during the process of the first conveyor belt 807 rotating and inverting the space manufacturing layer 18. If the paste is not firm, the adsorption device stops adsorbing the corresponding space manufacturing layer 18, and the space manufacturing layer 18 that stops being adsorbed falls into the waste bin 813 and does not enter the next process. During the process of the first conveyor belt 807 rotating and inverting the space manufacturing layer 18, the multi-item urine analysis test strips 10 or the absorbent pad 65 with insecure paste will fall or be displaced. The inspection lamp 812 performs image inspection on the space manufacturing layer 18 in the vertical position. If the difference between the image and the preset image exceeds the threshold, it is determined that the paste is not firm.

[0070] In some other embodiments, a waste inspection component is provided between the test strip assembly component and the upper cover sealing component. The waste inspection component includes a weight sensor and a waste bin, and is used to inspect and determine whether the multi-item urine analysis test strips and the absorbent pad pasted and loaded therein are firm when the space manufacturing layer loaded with the finished multi-item urine analysis test strips is in a horizontal position after the transfer component rotates and inverts the space manufacturing layer. If the paste is not firm, it is pushed away from the conveyor belt and falls into the waste bin and does not enter the next process. After the transfer component rotates and inverts the space manufacturing layer, the multi-item urine analysis test strips 10 or the absorbent pad 65 with insecure paste will fall, resulting in a change in weight. If the difference between the weight sensed by the weight sensor and the preset weight exceeds the threshold, it is determined that the paste is not firm.

[0071] In some embodiments, the production line for manufacturing the multi-item urine analysis strip combination product further includes a splitting and packaging component after the upper cover sealing component. The splitting and packaging component tears the splitting line between the multi-item urine analysis strips according to the preset packaging specifications, and splits and packages the multi-item urine analysis strip combination products of different specifications.

[0072] Example 5

[0073] Steps for operating the multi - item urine analysis strip combination product in Example 3: First, separate the multi - item urine analysis strip from the combination product through the dividing line 211 to obtain a single multi - item urine analysis strip. Second, take a certain amount of urine and slowly and evenly pour the urine from the first end 191 to the second end 192 through the urine inlet 19 onto the multi - item urine analysis test strip 10 and soak it. Of course, the positions of the first end and the second end can be swapped. In some cases, while the multi - item urine analysis test strip 10 on the first platform 12 is being soaked, the excess liquid directly flows onto the second platform 13 through the inclined surface 14 and is absorbed by the absorbent pad. In this case, the horizontal height of the first platform 12 is higher than that of the second platform 13 both in the static state and in the use state. In other cases, when the multi - item urine analysis test strip 10 on the first platform 12 is soaked with urine and the urine does not directly flow onto the second platform 13 through the inclined surface 14, wait for 2 - 5 seconds to fully soak the multi - item urine analysis test strip 10, and then pour the multi - item urine analysis strip so that the excess liquid can flow onto the second platform 13 through the inclined surface 14 and be absorbed by the absorbent pad. In this case, the horizontal height of the first platform 12 in the static state is less than or equal to that of the second platform 13. The pouring angle of the multi - item urine analysis strip is equivalent to the included angle α formed between the first platform 12 and the inclined surface 14. When the formed included angle is less than 90°, the pouring angle is less than 90°, and when the formed included angle is greater than 90°, the pouring angle is greater than 90°. Finally, after the urine analysis test strip is soaked, wait for a certain time, obtain the test result by standard color comparison. The waiting time is about 30 seconds to 120 seconds, which is specifically determined according to the item composition of the multi - item urine analysis test strip 10. Finally, discard the used multi - item urine analysis strip.

[0074] In some other implementation cases, before adding urine to the multi - item urine analysis strip, tear the sealing film 20 on the upper cover layer 17. After adding urine to the multi - item urine analysis strip, reseal the sealing film 20. Finally, wait for a certain time to obtain the standard colorimetric test result through the sealing film 20, and then discard the multi - item urine analysis strip that has completed the test and is in a sealed state.

[0075] The above - mentioned operating steps can be completed manually by a person or by a testing instrument. When completed by a testing instrument, the groove space 16 formed on the back sides of the first platform 12, the second platform 13, and the inclined surface 14 of the multi - item urine analysis strip exactly matches the corresponding test strip holder in the instrument.

[0076] The above specific embodiments are used to explain the present invention rather than limit the present invention. Any modifications and changes made to the present invention within the spirit and scope of the claims of the present invention fall within the protection scope of the present invention.

Claims

1. A multi - item urine analysis strip combination product, Characterized in that: It includes a first multi - item urine analysis strip and a second multi - item urine analysis strip, and the first multi - item urine analysis strip and the second multi - item urine analysis strip are connected through an intersection part (21), and the intersection part (21) includes a breakable dividing line (211); The multi - item urine analysis strip is formed by enclosing an upper cover layer (17) and a space - making layer (18). The upper cover layer (17) and the space - making layer (18) are hermetically connected through the first adhesive layer and form a cavity (11); the cavity (11) includes a first platform (12) configured with a multi - item urine analysis test strip (10), a urine inlet (19) corresponding to the first platform (12), a second platform (13) configured with an absorption pad (65), and an inclined surface (14) for urine conduction; The first platform (12) and the second platform (13) are spaced apart by the inclined surface (14). After urine is added from the urine inlet, the horizontal height of the first platform (12) is greater than the horizontal height of the second platform (13), and urine flows from the first platform (12) along the inclined surface (14) to the second platform (13) and is absorbed by the absorption pad (65).

2. A multi - item urine analysis strip combination product according to claim 1, Characterized in that, The width of the upper cover layer (17) is greater than or equal to the width of the space - making layer (18), an extension part (174) is formed above the upper cover layer (17), and the intersection part (21) is located in the extension part (174).

3. A multi - item urine analysis strip combination product according to claim 2, Characterized in that, A sealing film (20) is arranged on the upper cover layer (17), and the sealing film (20) and the upper cover layer (17) are connected through a second adhesive layer.

4. A multi - item urine analysis strip combination product according to claim 3, Characterized in that, The width of the sealing film (20) is greater than the width of the upper cover layer (17), and the intersection part (21) is located in the extension part (174) of the sealing film.

5. A multi - item urine analysis strip combination product according to claims 1 - 4, Characterized in that, There are at least two second platforms (13) respectively arranged on both sides of the first platform (12) in the cavity (11).

6. A multi - item urine analysis strip combination product according to claim 5, Characterized in that, The multi - item urine analysis test strip (10) and the absorption pad (65) form a composite card (631) with a common bottom plate (63), and the composite card (631) is closely fitted with the bottom of the cavity (181).

7. A multi - item urine analysis strip combination product according to claim 6, the composite card (631) is adhered to the bottom of the cavity (181) through a third adhesive layer.

8. A manufacturing method of a multi - item urine analysis strip combination product, Characterized in that, It includes the following steps: S1. Obtain the space manufacturing layer (18) and the upper cover layer (17). The space manufacturing layer (18) includes a first platform (12), a second platform (13), and an inclined surface (14) connecting the first platform (12) and the second platform (13). The upper cover layer (17) includes an intersection part (21) with a breakable dividing line (211). S2. Sequentially prepare large cards for test items (61), cut them to obtain single small cards for test items (62), paste multiple single small cards for test items (62) onto the base card (101), and then cut to obtain a multi-item urine analysis test strip (10). S3. Cut the absorbent pad large card (64) to obtain the absorbent pad (65). S4. Paste the multi-item urine analysis test strip (10) and the absorbent pad (65) onto the first platform (12) and the second platform (13). S5. Sealingly connect the upper cover layer (17) and the space manufacturing layer (18) through a first adhesive layer to form a cavity (11).

9. A manufacturing method of a multi-item urine analysis strip combination product according to claim 8, wherein, in step S1, the step of obtaining the space manufacturing layer (18) is to heat the coil material and direct it towards the mold opening (8041), move the mold (804), and evacuate air through the air holes (8043) at the bottom of the mold to form the space manufacturing layer (18), and then cut to obtain a single space manufacturing layer (18).

10. A manufacturing method of a multi-item urine analysis strip combination product according to claim 9, wherein, before step S5, rotate and invert the space manufacturing layer (18).

11. A manufacturing method of a multi-item urine analysis strip combination product according to claim 10, wherein, during the process of rotating and inverting the space manufacturing layer (18), inspect the bonding strength of the multi-item urine analysis test strip (10) and the absorbent pad (65).

12. A manufacturing method of a multi-item urine analysis strip combination product according to any one of claims 8 - 11, wherein, in step S5, a continuously heated sealing ring (811) forms a "0"-shaped weld line in the circumferential direction of the connecting part (171).

13. A production line applying the manufacturing method of a multi-item urine analysis strip combination product according to any one of claims 8 - 12, wherein, it includes a space manufacturing component, a test strip assembly component, an upper cover sealing component, a transmission component, and a finished product receiving component; the space manufacturing component includes a first loading roller (801) loaded with a flexible coil material, a heating bin (803) for heating the flexible material, a mold (804) for forming the space manufacturing layer, an air extraction device (805), and a cutting device (806) for obtaining a single space manufacturing layer (18); the test strip assembly component includes a glue head (808) for outputting an adhesive and a gripper for grasping the multi-item urine analysis test strip (10); the upper cover sealing component includes a second loading roller (810) loaded with a flexible upper cover coil material and a sealing ring (811) for heating to seal the space manufacturing layer (18) and the upper cover layer; The transmission component includes a conveyor belt, and the conveyor belt runs through between the space manufacturing component, the test strip assembly component, the upper cover sealing component, and the finished product receiving component.

14. A production line for manufacturing a multi-item urine analysis strip combination product according to claim 13, wherein, it further includes a waste inspection component located after the test strip assembly component, and the waste inspection component determines the adhesion strength between the multi-item urine analysis test strip (10) and the absorbent pad (65) in the space manufacturing layer after being rotated and inverted.

15. A production line for manufacturing a multi-item urine analysis strip combination product according to claim 13, wherein, it further includes a splitting and packaging component located after the upper cover sealing component, and the splitting and packaging component splits and packages multi-item urine analysis strip combination products of different specifications.

16. A usage method of a multi-item urine analysis strip combination product, applying the multi-item urine analysis strip combination product according to any one of claims 1-7, wherein: S1, separate a single multi-item urine analysis strip through the dividing line (211); S2, collect a certain amount of urine, and slowly and evenly pour the urine from the first end (191) to the second end (192) through the urine inlet (19) so that the urine wets the multi-item urine analysis test strip (10); S3, wait for a certain period of time and obtain the test result through standard color comparison.

17. A usage method of a multi-item urine analysis strip combination product according to claim 16, wherein, when in a static state, the horizontal height of the first platform (12) is equal to or less than the horizontal height of the second platform (13). After step S2, wait for a certain period of time, and tilt the multi-item urine analysis strip at an angle equivalent to α so that the excess urine flows from the first platform (12) to the second platform (13) along the inclined surface (14) and is absorbed by the absorbent pad (65).

18. A usage method of a multi-item urine analysis strip combination product according to claim 16, wherein, before step S2, tear open the sealing film (20) of the upper cover layer; before step S3, re-seal the sealing film (20); in step S3, obtain the test result through the sealing film (20), and then discard the multi-item urine analysis strip in the sealed state.

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