Sample analyzer, storage module and analysis system

Abstract

The invention provides a sample analyzer, a storage module and an analysis system. The sample analyzer comprises a sample supply mechanism, a reagent supply mechanism, a sample separate injection mechanism, a reagent separate injection mechanism, a detection device, a freezing bin device and a first separate injection mechanism. The freezing bin device comprises a freezing bin, a fan, a shell cover and a bearing frame, the first container is used for storing quality control products / calibration products, the freezing bin is used for providing a refrigeration environment below zero DEG C, the bearing frame and the fan are arranged in the freezing bin, the freezing bin comprises a bin body and a cover body, and the cover body is used for opening or closing an opening of the bin body; the bearing frame is provided with a storage position for storing the first container; air enters the mounting space through the air inlet duct and exits through the air outlet duct, the air outlet duct is used for guiding airflow generated by the fan to the storage position, and the air inlet duct and the air outlet duct are different in direction. The air flow generated by the fan of the freezing bin flows through the storage position, so that uncondensed water vapor at the storage position is transferred, and the possibility that the first container is frozen is reduced.

Description

Technical Field

[0001] The present application relates to the technical field of in vitro diagnostic analysis, and particularly relates to a sample analyzer, a storage module and an analysis system. Background Art

[0002] For items such as quality control products, calibration products, some reagents, and some reference standards, in order to ensure their stability, they need to be stored at low temperature and frozen, for example, stored at -20°C. However, frost is extremely likely to occur in a low-temperature freezing environment. On the one hand, frost will deteriorate the heat transfer efficiency, resulting in the temperature of the stored items unable to be maintained at the target temperature. On the other hand, frost will cause the surface of the stored items to frost, which will cause the container storing the items to freeze and be difficult to take out. In addition, during the automatic quality control process, when the robotic arm retrieves the container, it may be unable to take out the container because the container is frozen, and thus the quality control test process cannot be completed. Summary of the Invention

[0003] In view of this, the embodiments of the present application are expected to provide a sample analyzer, a storage module and an analysis system, wherein the first container stored in the freezing chamber device is not easily frozen and is convenient to take out.

[0004] The first aspect of the embodiments of the present application provides a sample analyzer, including:

[0005] A sample supply mechanism for carrying a sample container containing a sample to be measured;

[0006] A reagent supply mechanism for carrying a reagent container containing a reagent;

[0007] A sample dispensing mechanism for adding the sample to a reaction container;

[0008] A reagent dispensing mechanism for adding the reagent in the reagent cavity to the corresponding reaction container;

[0009] A detection device for detecting a reaction solution containing the sample and the reagent in the reaction container to obtain a sample detection result;

[0010] A freezing chamber device, including a freezing chamber, a fan, a housing cover, and a carrier for carrying a first container, the first container is used for storing quality control products / calibration products, the carrier and the fan are both arranged in the freezing chamber, the freezing chamber includes a chamber body and a cover body, the chamber body has an opening, the cover body is used to open or close the opening, and the carrier has a storage position for storing the first container;

[0011] The housing has an installation space, an air inlet duct, and an air outlet duct. The fan is accommodated in the installation space. The installation space takes in air through the air inlet duct and discharges air through the air outlet duct. The air outlet duct is used to direct the air flow generated by the fan to the storage position, and the directions of the air inlet duct and the air outlet duct are different;

[0012] A first dispensing mechanism for adding the quality control product / calibration product in the first container retrieved from the freezing chamber to the corresponding reaction container;

[0013] The detection device is further configured to detect the mixture containing the quality control product / calibration product and the reagent in the reaction container to obtain a quality control / calibration detection result.

[0014] A second aspect of the embodiments of the present application provides a storage module, including:

[0015] A freezing chamber, a fan, a housing, and a carrier for carrying the first container. The first container is used to store the quality control product / calibration product. The freezing chamber is used to provide a refrigerating environment below zero degrees. The carrier and the fan are both arranged in the freezing chamber. The freezing chamber includes a chamber body and a cover body. The chamber body has an opening, and the cover body is used to open or close the opening. The carrier has a storage position for storing the first container;

[0016] The housing has an installation space, an air inlet duct, and an air outlet duct. The fan is accommodated in the installation space. The installation space takes in air through the air inlet duct and discharges air through the air outlet duct. The air outlet duct is used to direct the air flow generated by the fan to the storage position, and the directions of the air inlet duct and the air outlet duct are different.

[0017] A third aspect of the embodiments of the present application provides an analysis system, including:

[0018] An analyzer, a transfer mechanism, and the storage module provided in the second aspect of the embodiments of the present application. The transfer mechanism is used to transfer the first container in the freezing chamber to the analyzer for quality control / calibration testing;

[0019] Wherein, the analyzer includes:

[0020] A sample supply mechanism for carrying a sample container containing a sample to be measured;

[0021] A reagent supply mechanism for carrying a reagent container containing a reagent;

[0022] A sample dispensing mechanism for adding the sample to a reaction container;

[0023] A reagent dispensing mechanism for adding the reagent in the reagent cavity to the corresponding reaction vessel;

[0024] A detection device for detecting the reaction solution containing the sample and the reagent in the reaction vessel to obtain a sample detection result;

[0025] A first dispensing mechanism for adding the quality control product / calibration product in the first container retrieved from the freezing chamber to the corresponding reaction vessel;

[0026] The detection device is also used to detect the mixture containing the quality control product / calibration product and the reagent in the reaction vessel to obtain a quality control / calibration detection result.

[0027] The freezing chamber device of the sample analyzer according to the embodiment of the present application includes a freezing chamber, in which a carrier for carrying the first container and a fan are provided. The fan can direct the air flow to the carrier and the storage positions on the carrier for storing the first container. In this way, the air flow can disperse the water vapor entering the freezing chamber from the outside and located at the first container and the storage positions, and gradually transfer it to the inner surface of the surrounding freezing chamber, reducing the possibility of water vapor condensing between the first container and the carrier to form frost, and reducing the situation that the first container and the carrier are frozen and the first container cannot be taken out. In addition, reducing the frosting on the surface of the first container can also ensure the heat transfer efficiency, so that the first container can be maintained at the target temperature, thereby ensuring the stability and shelf life of the quality control product / calibration product stored in the first container. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 It is a schematic structural diagram of the freezing chamber device according to an embodiment of the present application, in which the cover is in an open state;

[0029] Figure 2 is Figure 1 a partial exploded structural diagram of the freezing chamber device shown;

[0030] Figure 3 is Figure 1 a schematic cross-sectional view of the freezing chamber device shown with the cover in a closed state Figure 1 ;

[0031] Figure 4 is Figure 1 a schematic cross-sectional view of the freezing chamber device shown with the cover in a closed state Figure 2 .

[0032] Figure 5 is Figure 1 a schematic structural diagram of the housing of the freezing chamber device shown;

[0033] Figure 6 isFigure 1 Schematic structural diagram of the limit frame of the freezing chamber device shown

[0034] Figure 7 For Figure 6 Schematic top view of the limit frame shown

[0035] Figure 8 Based on Figure 7 Schematic diagram showing the limit channel additionally indicated by a dashed line

[0036] Figure 9 For Figure 1 Schematic structural diagram of the support base of the freezing chamber device shown

[0037] Explanation of reference numerals

[0038] 1 - Freezing chamber; 11 - Chamber body; 111 - Opening; 12 - Cover body; 13 - Thermal insulation layer; 2 - Fan; 3 - Carrier frame; 3a - Storage position; 31 - Support base; 311 - Ventilation hole; 312 - Second cavity; 32 - Limit frame; 321 - Limit channel; 322 - Through hole; 323 - Plate body; 3231 - Through hole; 324 - Limit piece; 4 - Housing cover; 4a - Installation space; 41 - Inlet air duct; 42 - Outlet air duct; 43 - Bottom shell wall; 44 - Peripheral shell wall; 5 - Grille structure; 5a - Accommodation space; 51 - First cavity; 52 - Grille bar; 10 - First container; 100 - Freezing chamber device Detailed implementation manners

[0039] In order to make the objectives, technical solutions and advantages of the present invention clearer and more understandable, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention

[0040] For each specific technical feature described in the specific embodiments, they can be combined in any appropriate manner without conflict. For example, different embodiments and technical solutions can be formed by combining different specific technical features. To avoid unnecessary repetition, various possible combination manners of each specific technical feature in the present invention will not be described separately

[0041] In the following descriptions, the terms "first / second / ..." involved are only used to distinguish different objects and do not indicate that there are the same or related relationships between the objects. It should be understood that the orientation descriptions "above", "below", "outside", "inside" involved are all the orientations in the normal use state, and the "left" and "right" directions represent the left and right directions shown in the specific corresponding schematic diagrams, which can be the left and right directions in the normal use state or not

[0042] It should be noted that the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, such that a process, method, article or apparatus comprising a series of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article or apparatus. Without further limitation, an element defined by the statement "comprising an..." does not exclude the presence of additional identical elements in the process, method, article or apparatus comprising that element. "Plurality" means greater than or equal to two.

[0043] An embodiment of the present application provides a sample analyzer, which includes a sample supply mechanism, a reagent supply mechanism, a sample dispensing mechanism, a reagent dispensing mechanism and a detection device.

[0044] The sample supply mechanism is used to carry a sample container containing a sample to be measured. The sample supply mechanism can be a sample tray, and the sample tray includes a plurality of sample positions where sample tubes and the like can be placed. By rotating its disk structure, the sample tray can schedule the sample to a corresponding position, for example, the position for the sample dispensing mechanism to aspirate the sample. Of course, the sample supply mechanism can also be of other shapes.

[0045] The reagent supply mechanism is used to carry a reagent container containing a reagent. In some embodiments, the reagent supply mechanism can be a reagent tray, which is arranged in a disk-shaped structure and has a plurality of positions for carrying reagent bottles. The reagent supply mechanism can rotate and drive the reagent bottles carried thereon to rotate, so as to rotate the reagent bottles to a specific position, for example, the position for the reagent dispensing mechanism to aspirate the reagent.

[0046] The sample dispensing mechanism is used to add a sample to a reaction container. Exemplarily, the sample dispensing mechanism includes a moving member and a sample needle disposed on the moving member; the moving member is used to drive the sample needle to move between different operating positions to aspirate or discharge the sample. For example, the sample is aspirated by moving the sample needle to the sample carried by the sample supply mechanism, and then moved to the reaction container to be loaded with the sample, and the sample is discharged into the reaction container.

[0047] The reagent dispensing mechanism is used to add the reagent in the reagent container to the corresponding reaction container. For example, the reagent dispensing mechanism is configured with a reagent needle, and the reagent in the reagent container carried by the reagent supply mechanism is aspirated by moving the reagent needle, and then moved to the reaction container to be loaded with the reagent, and the reagent is discharged into the reaction container.

[0048] The detection device is used to detect the reaction solution containing the sample and the reagent in the reaction container to obtain a sample detection result. For example, the detection device performs photometric analysis on the reaction solution to be measured, and calculates the concentration of the component to be measured in the sample through a calibration curve, etc.

[0049] It should be noted that the optical measurement analysis can be used for immunoassay, biochemical analysis, coagulation analysis, hemorheological analysis, etc.

[0050] Exemplarily, in some embodiments, the sample analyzer further includes a mixing mechanism for mixing the reaction liquid to be mixed in the reaction container. Exemplarily, the mixing mechanism is configured with a stirring rod for mixing and stirring the reaction liquid to be mixed in the reaction container.

[0051] The number of the mixing mechanisms can be one or more.

[0052] Exemplarily, in some embodiments, the sample analyzer further includes a reaction component having at least one placement position for placing the reaction container and incubating the reaction liquid in the reaction container, where the reaction liquid is obtained by mixing the sample provided by the sample dispensing mechanism and the reagent provided by the reagent dispensing mechanism. For example, the reaction component can be a reaction disk, which is arranged in a disk-shaped structure and has one or more placement positions for placing the reaction container. The reaction disk can rotate and drive the reaction container in its placement position to rotate, for scheduling the reaction container in the reaction disk and incubating the reaction liquid in the reaction container.

[0053] As Figures 1 to 4 shown, the sample analyzer further includes a freezing chamber device 100. The freezing chamber device 100 includes a freezing chamber 1, a fan 2, and a carrier 3 for carrying the first container 10. The first container 10 is used for storing quality control products / calibration products.

[0054] The freezing chamber 1 is used to provide a refrigerating environment below zero degrees, and can freeze and store the quality control products / calibration products that need to be frozen. For example, the freezing chamber 1 can provide a freezing storage temperature of -10°C to -30°C.

[0055] It should be noted that after the quality control products / calibration products are dispensed into the first container 10, they need to be stored at a low temperature below zero degrees. Generally, the samples provided by the sample supply mechanism, the reagents provided by the reagent supply mechanism, etc. only need to be stored in refrigeration above zero degrees and do not need to be stored in freezing below zero degrees.

[0056] The carrier 3 and the fan 2 are both arranged in the freezing chamber 1.

[0057] The freezing chamber 1 includes a chamber body 11 and a cover body 12. The chamber body 11 has an opening 111, and the cover body 12 is used to open or close the opening 111. It should be noted that in some embodiments, when the cover body 12 is opened, the cover body 12 can be completely removed from the chamber body 11, and there is no connection relationship between the two. In other embodiments, the cover body 12 can also always be connected to the chamber body 11 and the two will not be completely separated.

[0058] The cover 12 is opened or closed under an external force, thereby opening or closing the opening 111. Herein, the external force can be, for example, the force applied by a driving mechanism, or the force applied by a human body, etc.

[0059] In some embodiments, the freezing chamber 1 further includes a heat-insulating layer 13, and the heat-insulating layer 13 is wrapped around the outer periphery of the chamber body 11, so that it can play a role in heat preservation and heat insulation for the chamber body 11, reduce the heat exchange between the inside and the outside of the chamber body 11, save energy, and reduce the energy consumption of the freezing chamber 1.

[0060] The carrier 3 has a storage position 3a for storing the first container 10. The specific number of the storage positions 3a is not limited. For example, there can be one or more. Specifically, the first container 10 is placed in the storage position 3a, and the carrier 3 is used to carry the first container 10 and limit the first container 10, so that the placement of the first container 10 is more stable and reliable.

[0061] The specific type of the first container 10 is not limited. For example, it can be in a tubular structure.

[0062] The size of the tubular structure can be the same as the external dimension of the sample tube. In some embodiments, the first container 10 can be an adapter. Thus, after the tubular structure is removed from the freezing chamber and thawed, it can be directly placed in the sample position of the reagent supply mechanism for subsequent detection.

[0063] When it is necessary to take out the first container 10 stored in the freezing chamber 1, it is necessary to first open the cover 12, and then take out the first container 10 stored in the chamber body 11 and place it at a specified position. When the freezing chamber 1 is in a frozen state, the inside of the chamber body 11 always maintains a low-temperature environment, and the items stored in the chamber body 11 will also always be in a low-temperature state. However, the ambient temperature and humidity outside are higher than the ambient temperature and humidity inside the chamber body 11. Therefore, when the cover 12 is in an open state, the low-temperature and dry environment inside the chamber body 11 will have an air convection exchange with the high-temperature and high-humidity environment outside. At this time, the high-temperature and high-humidity air outside will enter the inside of the chamber body 11 and frost will occur when it meets the cold inside the chamber body 11. If it cannot be processed in time, frost may form on the surface of the first container, the carrier, or the junction between the first container and the carrier, etc. On the one hand, if frost forms on the surface of the first container, the heat transfer efficiency will deteriorate, resulting in the temperature of the stored first container not being able to be maintained at the target temperature, which may affect the stability and shelf life of the quality control products / calibration products stored in the first container. On the other hand, if frost forms at the junction between the first container and the carrier, etc., the first container will be frozen on the carrier, making it impossible to smoothly take out the first container when it is necessary to take out the first container, thus affecting the subsequent test process.

[0064] Therefore, as Figure 1 、 Figure 3, Figure 4 and Figure 5 As shown in Figure 4 and Figure 5 , the freezing chamber device of the embodiment of the present application further includes a fan 2 and a housing 4.

[0065] The housing 4 has an installation space 4a, an air inlet duct 41, and an air outlet duct 42. The fan 2 is accommodated in the installation space 4a. The installation space 4a intakes air through the air inlet duct 41 and discharges air through the air outlet duct 42. The air outlet duct 42 is used to direct the airflow generated by the fan 2 to the storage position 3a. The directions of the air inlet duct 41 and the air outlet duct 42 are different.

[0066] After the fan 2 is started, the fan 2 drives the air flow in the freezing chamber 1. The housing 4 can play a certain guiding role in the gas flow in the chamber body 11. The air outlet duct 42 directs the airflow generated by the fan 2 to the storage position 3a. The airflow flows through the first container 10 on the storage position 3a. In this way, the water vapor that has not completely condensed can be dispersed, so that the water vapor that has not completely condensed can be driven by the airflow to transfer to other positions outside the storage position 3a, for example, to the inner surface of the chamber body 11, so that frost forms on the inner surface of the chamber body 11 instead of on the storage position 3a or the surface of the first container 10 on the storage position 3a. In this way, the possibility of frosting and freezing on the surface of the first container 10 or between the first container 10 and the carrier 3 is reduced; the situation where the first container 10 cannot be taken out due to being frozen between the first container 10 and the carrier 3 is reduced, so that the subsequent test process can proceed smoothly. In addition, since the directions of the air inlet duct 41 and the air outlet duct 42 are different, the gas can form a stable air flow circulation channel in the chamber body 11 through the air inlet duct 41 and the air outlet duct 42 provided on the housing 4, ensuring the reliability of the airflow flowing through the first container 10 and facilitating ensuring that the airflow carries water vapor and condenses on the inner surface of the chamber body 11.

[0067] In addition, in this embodiment, it can also play a role in reducing the frequency of the defrosting operation of the freezing chamber. Specifically, when the first container is frosted, it may cause the first container to be unable to be taken out, and at this time, defrosting may need to be started; or, when the frosting degree on the inner surface of the freezing chamber is relatively high, the defrosting operation also needs to be started to achieve the defrosting purpose. However, if the defrosting operation is started frequently, it is easy to damage the refrigeration structure and the heating structure of the freezing chamber.

[0068] In the embodiment of the present application, the frosting probability of the first container 10 can be reduced, so the frequency of defrosting can be reduced to a certain extent, thereby playing a protective role in the refrigeration structure and the heating structure of the freezing chamber.

[0069] In addition, the housing 4 can play a certain protective role for the fan 2, avoiding the situation where the fan 2 is damaged due to the impact of external components such as a manipulator when the cover body 12 is opened.

[0070] Exemplarily, such asFigure 5 As shown, the air inlet of the air inlet duct 41 is generally strip-shaped and extends in the horizontal direction. In this way, while not affecting the inflow of gas into the installation space 4a, the fan 2 can be visually blocked, reducing the possibility for the user to see the fan 2 through the housing 4 when opening the cover 12, thereby enhancing the aesthetics and ensuring visual unity.

[0071] Exemplarily, the air outlet of the air outlet duct 42 is generally fan-shaped, so that the air outlet efficiency can be ensured.

[0072] Those skilled in the art should understand that the embodiments of the present application do not specifically limit the shapes of the air inlet of the air inlet duct 41 and the air outlet of the air outlet duct 42, and they can also be in any other suitable shapes.

[0073] The sample analyzer further includes a first dispensing mechanism, and the first dispensing mechanism is used to add the quality control product / calibration product in the first container 10 retrieved from the freezing chamber 1 to the corresponding reaction container.

[0074] In some embodiments, the first dispensing mechanism and the sample dispensing mechanism are the same mechanism. In this embodiment, in addition to dispensing samples, the sample dispensing mechanism is also used to dispense the quality control product / calibration product in the first container 10. In other embodiments, the first dispensing mechanism and the sample dispensing mechanism are two independent different mechanisms.

[0075] In some embodiments, the detection device is used not only to detect the reaction solution containing the sample and the reagent in the reaction container, but also to detect the mixed solution containing the quality control product / calibration product and the reagent in the reaction container to obtain the quality control / calibration detection result.

[0076] In some embodiments, one of the air outlet duct 42 and the air inlet duct 41 is arranged in the vertical direction, and the other is arranged in the horizontal direction. On the one hand, it is convenient to arrange the air outlet duct 42 and the air inlet duct 41 on the housing 4. On the other hand, it is beneficial to make the gas flow through almost all the surfaces inside the chamber 11, fully utilize the inner surface of the chamber 11, improve the frosting uniformity of the inner surface of the chamber 11, and extend the time interval between two adjacent defrostings.

[0077] Exemplarily, as Figure 5 shown, the air inlet duct 41 is arranged in the horizontal direction, and the air outlet duct 42 is arranged in the vertical direction.

[0078] Exemplarily, the air inlet duct 41 is arranged in the vertical direction, and the air inlet duct 41 is arranged in the horizontal direction.

[0079] In some embodiments, as Figure 3 and Figure 4As shown, the fan 2 is disposed on the cover body 12. In this way, the cover body 12 can be fully utilized to carry the fan 2, eliminating the need to create additional space in the storage chamber 11 for accommodating the fan 2, making the overall structure of the freezing chamber 1 more compact.

[0080] Specifically, when the cover body 12 is in the closed state, the fan 2 is located above the carrier 3, and the air outlet duct 42 faces the side where the bottom surface of the storage chamber 11 is located, that is, the air inlet duct 41 is arranged in the vertically downward direction. In this way, the airflow generated by the fan 2 can flow directly towards the carrier 3 through the air outlet duct 42, thereby dispersing the still-uncompletely condensed water vapor on the surface of the carrier 3 and the first container 10 carried on the carrier 3, reducing the possibility of frost formation on the surfaces of the first container 10 and the carrier 3, ensuring the heat transfer efficiency of the first container 10, and reducing the occurrence of the situation where the first container 10 is frozen on the carrier 3 and cannot be taken out.

[0081] Of course, those skilled in the art should understand that in some other embodiments, the fan 2 and the housing 4 can also be disposed in the storage chamber 11.

[0082] In some embodiments, as Figure 5 shown, the housing 4 has a bottom housing wall 43 that faces the side where the bottom surface of the storage chamber 11 is located, and the air outlet duct 42 is disposed on the bottom housing wall 43. And / or, the housing 4 has a peripheral housing wall 44 that surrounds the circumference of the fan 2, and the air inlet duct 41 is disposed on the peripheral housing wall 44.

[0083] In this way, vertical air outlet and horizontal air inlet can be achieved. The vertical air outlet enables the gas generated by the fan 2 to flow directly towards the side where the bottom surface of the storage chamber 11 is located, that is, directly towards the side where the carrier 3 is located, reducing the possibility of frosting on the surface of the first container 10 carried on the carrier 3 and the frosting between the first container 10 and the carrier 3. In addition, the airflow blowing towards the inner surface of the storage chamber 11 can flow upward along the inner surface of the storage chamber and enter the installation space through the peripheral housing wall 44, so that the corners in the storage chamber 11 can also have gas flowing through, enabling all parts of the storage chamber 11 to be used for frosting, making full use of the inner surface of the storage chamber 11, and improving the frosting uniformity of the inner surface of the storage chamber 11.

[0084] In some embodiments, the freezing chamber device further includes a grille structure 5. The grille structure 5 defines an accommodation space 5a. The carrier 3 is located in the accommodation space 5a. The fan 2 is used to blow air towards the accommodation space 5a. The grille structure 5 enables air communication between the accommodation space 5a and the inner surface of the storage chamber 11.

[0085] When the cover body 12 is in a closed state, the fan 2 can blow air towards the accommodating space 5a. The air flow generated by the fan 2 will first flow through the accommodating space 5a, then flow through the grilles on the grille structure 5 towards the inner surface of the bin body 11, and finally flow back to the fan 2 through the air inlet duct 41, enabling the gas to form a cycle. In this way, the air flow generated by the fan 2 can drive the water vapor to transfer inside the bin body 11, thereby being able to reduce the frosting speed inside the bin body 11. Moreover, since the grille structure 5 forms an air connection between the accommodating space 5a and the inner surface of the bin body 11, the water vapor in the accommodating space 5a can be driven by the air flow to pass through the grille structure 5 and transfer to the inner surface of the bin body 11. And when a part of the air flow is rebounded by the inner surface of the bin body 11, even if a part of the ice crystals is carried by the air flow and rebounded by the inner surface of the bin body 11, the grille structure 5 can play a certain role in blocking the ice crystals, further reducing the probability of frosting in the accommodating space 5a.

[0086] In addition, the grille structure 5 can also play a role in visual occlusion, presenting a frost-free visual perception to a certain extent, that is, there is no frost visible to the naked eye (because the frosting is not inside the grille structure 5 but on the inner surface of the bin body 11 and is blocked by the grille structure 5), improving the user experience.

[0087] In some embodiments, as Figure 3 and Figure 4 shown, at least a part of the outer peripheral surface of the grille structure 5 is spaced from the inner surface of the peripheral side of the bin body 11 and defines a first cavity 51, and the first cavity 51 surrounds the outer periphery of the grille structure 5.

[0088] The first cavity 51 can reserve a certain accommodating space for the frost formed on the inner surface of the bin body 11, so that the formed frost can be temporarily stored between the inner surface of the bin body 11 and the outer peripheral surface of the grille structure 5. In this way, when the frost fills the space of the first cavity 51, the whole freezer 1 can be defrosted, thereby being able to extend the time for overall defrosting of the freezer 1, avoid frequent defrosting, improve the service life of the refrigeration structure and the heating structure of the freezer 1, and be beneficial to cost saving.

[0089] Specifically, as Figure 2 shown, the grille structure 5 includes a plurality of grille bars 52, the grille bars 52 extend in the horizontal direction, and the plurality of grille bars 52 are arranged at intervals in the height direction. Specifically, the gap between two adjacent grille bars 52 allows the air flow to pass through.

[0090] In this embodiment, while ensuring the air connection between the accommodating space 5a and the inner surface of the bin body 11, it can play a role in visually occluding the frost. When the user opens the cover body 12, it is not easy to see the frost in the first cavity 51 through the grille structure 5, enhancing the aesthetics and further improving the user's perception of no frost visible to the naked eye.

[0091] The overall shape of the grille structure 5 generally adapts to the shape of the inner surface of the bin body 11. For example, in some embodiments, the peripheral wall of the bin body 11 is generally rectangular, and the grille structure 5 is also generally rectangular. Specifically, the grille structure 5 includes four side wall surfaces, and each side wall surface includes a plurality of grille bars 52 extending in the horizontal direction and arranged in the height direction.

[0092] The specific number of the grille bars 52 is not limited.

[0093] Of course, those skilled in the art should understand that in some other embodiments, the grille bars 52 may also extend in the height direction, and a plurality of grille bars 52 are arranged in the horizontal direction, or the grilles of the grille structure 5 are not in a long strip shape, but in any other suitable shape, such as square grilles, circular grilles, etc.

[0094] In some embodiments, as Figures 2 to 4 , Figures 6 to 9 shown, the carrier 3 includes a support base 31 and a limit frame 32. The limit frame 32 is located above the support base 31. The limit frame 32 has at least one limit channel 321 for accommodating the first container 10, and the support base 31 is used to support the bottom of the first container 10.

[0095] Specifically, the first container 10 can pass through the limit channel 321 of the limit frame 32 and be supported on the support base 31. The setting of the limit frame 32 can make the first container 10 placed more stably when stored in the freezing bin 1, reduce the possibility of accidents such as leakage of the quality control products / calibration products stored in the first container 10 caused by the first container 10 tipping over, and improve the reliability of the freezing bin device.

[0096] The shape of the limit channel 321 is not limited as long as it allows the first container 10 to pass through. The number of the limit channels 321 is also not limited, and it can be one or more.

[0097] The shape of the limit channel 321 adapts to the cross-sectional shape of the first container 10. For example, both are circular.

[0098] As Figure 9 shown, the support base 31 has ventilation holes 311, and the ventilation holes 311 communicate the space above the support base 31 and the bottom surface of the bin body 11.

[0099] The number of ventilation holes 311 is multiple, and the multiple ventilation holes 311 are arranged at intervals on the support base 31. Thus, the water vapor in the accommodation space 5a can also be driven by the airflow generated by the fan 2 to pass through the ventilation holes 311 and transfer to the bottom surface of the bin body 11, and condense on the bottom surface of the bin body 11 to form frost, thereby transferring the position where frost forms in the bin body 11, reducing the possibility of frost formation in the accommodation space 5a, ensuring that the first container 10 can be maintained at the target temperature and reducing the possibility of the first container 10 not being taken out smoothly.

[0100] In addition, arranging the ventilation holes 311 can also reduce the contact area between the first container 10 and the support base 31, thereby reducing the possibility of water vapor adhering between the first container 10 and the support base 31, and further reducing the possibility of frost formation between the first container 10 and the support base 31. In addition, the ventilation holes 311 can also improve the heat exchange capacity between the bottom surface of the bin body 11 and the first container 10, which is beneficial to the transfer of the cooling capacity from the bottom surface of the bin body 11 to the bottom of the first container 10.

[0101] In some embodiments, such as Figure 3 and Figure 4 shown, at least part of the support base 31 is spaced from the bottom surface of the bin body 11 and defines a second cavity 312.

[0102] The second cavity 312 can reserve a certain accommodation space for the frost formed on the bottom surface of the bin body 11, so that the formed frost can be temporarily stored between the bottom surface of the bin body 11 and the lower surface of the support base 31. In this way, the accommodation space for frost in the bin body 11 can be further increased. When the frost fills the spaces of the first cavity 51 and the second cavity 312, the entire freezer 1 can be defrosted as a whole, which can further extend the time for defrosting the entire freezer 1 as a whole, avoid frequent defrosting, improve the service life of the refrigeration structure and the heating structure of the freezer 1, and is beneficial to cost saving.

[0103] Such as Figure 7 shown, the limiting frame 32 has at least one through hole 322, and the through hole 322 communicates with the corresponding limiting channel 321. The through hole 322 enables the air to communicate between the upper and lower opposite sides of the limiting frame 32. Thus, the uncondensed water vapor can be driven by the airflow generated by the fan 2 to enter the space below the limiting frame 32 through the through hole 322, reducing the possibility of freezing between the first container 10 and the limiting frame 32. In addition, since the through hole 322 communicates with the corresponding limiting channel 321, it is beneficial for the air blown by the fan 2 to flow along the entire surface of the first container 10, thereby being beneficial to blowing away the condensed water vapor on the surface of the first container 10 with almost no residue. In some embodiments, such as Figures 6 to 8 shown, the limiting frame includes a plate body 323.

[0104] In some embodiments, a hole may be directly opened on the plate body 323 to form the limiting channel 321 , and a portion of the hole wall of the limiting channel 321 is dug out to form the above-mentioned through opening 322 .

[0105] In some embodiments, the limiting frame 32 further includes at least one group of limiting pieces 324 disposed on the bottom side of the plate body 323, and each group of limiting pieces 324 includes at least two limiting pieces 324. Figure 8 The plate body 323 is provided with a through hole 3231, and each group of limiting plates 324 is arranged at the edge of the bottom side of the corresponding through hole 3231. The top end of the limiting plate 324 is connected to the plate body 323, and the bottom end of the limiting plate 324 is a free end. Each group of limiting plates 324 defines a limiting channel 321.

[0106] It should be noted that if Figure 7 and Figure 8 As shown, in the projection of the plane where the plate body 323 is located, the projection range of the limiting channel 321 is located within the projection range of the through hole 3231, but the two do not overlap, wherein, Figure 8 The dotted line in the figure schematically shows the projection range of the limiting channel 321 , and the portion of the through hole 3231 located outside the projection range of the limiting channel 321 constitutes the above-mentioned through opening 322 .

[0107] The limiting piece 324 can play a better limiting role on the first container 10, so that the placement of the first container 10 is more stable and reliable.

[0108] Specifically, compared with the top end, the free end of the limiting piece 324 is arranged closer to the axial direction of the limiting channel 321, that is, the limiting piece 324 is generally inclined, and the limiting channel 321 defined by the limiting piece 324 is generally in the shape of an inverted cone. In this way, when the first container 10 is placed in the limiting frame 32, the limiting piece 324 is configured as a structure similar to a spring sheet, which can undergo elastic deformation, thereby playing a certain clamping effect on the first container 10, thereby better limiting the first container 10.

[0109] In some embodiments, the sample analyzer includes a transfer mechanism and a controller, and the controller is used to control the transfer mechanism to move the first container 10 out of the freezing chamber 1 and transfer it to the liquid aspiration position of the first dispensing mechanism for aspiration, so as to perform quality control / calibration testing, thereby enabling the transfer of the first container 10 in an automated manner, thereby improving the degree of automation. Since the first container 10 is not prone to frost, during the process of automatically transferring the first container 10, it is not easy to encounter the unfavorable situation that the first container 10 cannot be taken out due to being frozen, which is conducive to the automated completion of the quality control test process.

[0110] The transfer mechanism includes but is not limited to a robotic arm.

[0111] The controller includes, but is not limited to, a processor and a storage medium storing a computer program.

[0112] In some embodiments, the sample analyzer includes a driving mechanism connected to the cover 12. The controller is further configured to control the movement of the driving mechanism to drive the cover 12 to open and / or close the cover through the driving mechanism. In this way, the opening and / or closing of the cover 12 can be realized in an automated manner, and the automated test of quality control / calibration can be realized.

[0113] The driving mechanism includes, but is not limited to, a motor.

[0114] Of course, those skilled in the art should understand that the cover 12 can also be opened and / or closed manually by the user.

[0115] In some embodiments, the controller is configured to control the fan 2 to rotate after the cover 12 is closed, so as to automatically realize the rotation of the fan 2 after the cover is closed, so that the water vapor that has just entered the chamber 11 and has not yet condensed can be blown away or transferred to the inner surface and / or bottom surface of the chamber in time, reducing the possibility of water vapor condensing into frost on the surface of the first container 10 and the carrier 3.

[0116] In some embodiments, the controller is further configured to control the fan 2 to remain closed after the cover 12 is opened, so as to automatically realize the closing of the fan 2 after the cover is opened, save energy, and avoid adverse effects on the quality control test process due to the airflow generated by the fan 2; in addition, it can also prevent the fan 2 from blowing more air into the chamber 11.

[0117] In some embodiments, the sample analyzer further includes a detection module configured to detect the environmental parameters outside the freezing chamber 1 and obtain environmental parameter information. The environmental parameters include at least one of temperature and humidity. The controller is configured to control the rotation duration of the fan 2 according to the environmental parameter information.

[0118] The higher the humidity outside the freezing chamber 1, the more water vapor enters the freezing chamber 1. Similarly, the higher the environmental temperature outside the freezing chamber 1, the more water vapor content in the air. Therefore, when the temperature or humidity outside the freezing chamber 1 is higher, the rotation duration of the fan 2 needs to be longer, so as to fully blow and transfer the water vapor. When the temperature or humidity outside the freezing chamber 1 is lower, the fan 2 does not need to be started for a long time, which is beneficial to saving energy. Therefore, by detecting the environmental parameters outside the freezing chamber 1 through the detection module, the rotation duration of the fan 2 can be controlled in an automated manner, effectively saving energy while ensuring that frost is not easily generated in the accommodation space 5a.

[0119] In some embodiments, the sample analyzer includes a timing module for recording the time of a single lid opening, and a controller for controlling the rotation duration of the fan 2 according to the single lid opening time.

[0120] The longer the lid opening time of the lid 12, the more outside air will enter the freezing chamber 1, and thus more water vapor will be formed in the freezing chamber 1. Therefore, the longer the rotation duration of the fan 2 is required. Therefore, the sample analyzer can also be provided with a timing module that can automatically record the time when the lid 12 is opened, so as to control the rotation duration of the fan 2 in an automated manner. While ensuring that frost is not easily generated in the accommodation space 5a, energy can be effectively saved.

[0121] An embodiment of the present application provides a storage module, which includes a freezing chamber 1, a fan 2, a housing 4, and a carrier 3 for carrying the first container 10. The first container 10 is used to store quality control products / calibration products. The freezing chamber 1 is used to provide a refrigerating environment below zero degrees. The carrier 3 and the fan 2 are both arranged in the freezing chamber 1. The freezing chamber 1 includes a chamber body 11 and a lid 12. The chamber body 11 has an opening 111. The lid 12 is used to open or close the opening 111. The carrier 3 has a storage position 3a for storing the first container 10. The housing 4 has an installation space 4a, an air inlet duct 41, and an air outlet duct 42. The fan 2 is accommodated in the installation space 4a. The installation space 4a intakes air through the air inlet duct 41 and discharges air through the air outlet duct 42. The air outlet duct 42 is used to direct the airflow generated by the fan 2 to the storage position 3a. The directions of the air inlet duct 41 and the air outlet duct 42 are different.

[0122] In this way, the airflow can disperse the water vapor that enters the freezing chamber 1 from the outside and is located at the first container 10 and the storage position 3a, and gradually transfer it to the inner surface of the surrounding freezing chamber 1, reducing the possibility of water vapor condensing between the first container 10 and the carrier 3 to form frost, and reducing the situation where the first container 10 and the carrier 3 are frozen and the first container 10 cannot be taken out. In addition, reducing frosting on the surface of the first container 10 can also ensure the heat transfer efficiency, so that the first container 10 can be maintained at the target temperature, thereby ensuring the stability and shelf life of the quality control products / calibration products stored in the first container 10.

[0123] The storage module here is equivalent to the freezing chamber device 100 described above. In some embodiments, the storage module may be included in the sample analyzer itself, belonging to a module in the sample analyzer, and the transfer mechanism in the sample analyzer is used to grasp and transfer the first container 10 stored in the storage module. In other embodiments, the storage module may also be set separately and cascaded with the sample analyzer to form an analysis system, and the first container 10 stored in the storage module is grasped and transferred to the sample analyzer through a separate transfer mechanism or through the transfer mechanism of the sample analyzer for corresponding quality control / calibration tests.

[0124] The storage module includes a controller for controlling the fan 2 to rotate after the cover 12 is closed; and / or, the storage module includes a driving mechanism, and the controller is further used to control the movement of the driving mechanism to drive the cover 12 to open or close through the driving mechanism.

[0125] In this way, the opening or closing of the cover 12 can be controlled in an automated manner, and the fan 2 can be controlled to rotate in an automated manner after the cover is closed, which is beneficial to improving the degree of automation and realizing the automated test of quality control / calibration.

[0126] The embodiment of the present application also provides an analysis system, which includes an analyzer, a transfer mechanism, and the storage module described in any one of the above embodiments. The transfer mechanism is used to transfer the first container 10 in the freezing chamber 1 to the analyzer for the analyzer to perform quality control / calibration tests.

[0127] Among them, the analyzer includes a sample supply mechanism, a reagent supply mechanism, a sample dispensing mechanism, a reagent dispensing mechanism, a detection device, and a first dispensing mechanism.

[0128] The sample supply mechanism is used to carry the sample container containing the sample to be measured. The reagent supply mechanism is used to carry the reagent container containing the reagent. The sample dispensing mechanism is used to add the sample to the reaction container.

[0129] The reagent dispensing mechanism is used to add the reagent in the reagent chamber to the corresponding reaction container.

[0130] The detection device is used to detect the reaction solution containing the sample and the reagent in the reaction container to obtain the sample detection result.

[0131] The first dispensing mechanism is used to add the quality control product / calibration product in the first container 10 retrieved from the freezing chamber to the corresponding reaction container.

[0132] The detection device is also used to detect the mixed solution containing the quality control product / calibration product and the reagent in the reaction container to obtain the quality control / calibration detection result.

[0133] In this embodiment, the analyzer and the storage module are separately provided and cascaded to form an analysis system.

[0134] In the description of the present application, the description with reference to terms such as "one embodiment", "some embodiments", "examples", "specific examples", or "some examples" means that the specific features, structures, materials, or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the embodiments of the present application. In the present application, the schematic expression of the above terms is not necessarily directed to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described can be combined in any one or more embodiments or examples in a suitable manner. In addition, without contradiction, those skilled in the art can combine the different embodiments or examples described in the present application and the features of the different embodiments or examples.

[0135] The foregoing is only a preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application can have various changes and modifications. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included within the protection scope of the present application.

Claims

1. A sample analyzer, characterized in that, comprising: a sample supply mechanism for carrying a sample container containing a sample to be measured; a reagent supply mechanism for carrying a reagent container containing a reagent; a sample dispensing mechanism for adding the sample to a reaction container; a reagent dispensing mechanism for adding the reagent in the reagent chamber to the corresponding reaction container; a detection device for detecting a reaction solution containing the sample and the reagent in the reaction container to obtain a sample detection result; a freezing chamber device, including a freezing chamber, a fan, a housing cover, and a carrier for carrying a first container for storing a quality control product / calibration product, the freezing chamber for providing a refrigeration environment below zero degrees, the carrier and the fan are both arranged in the freezing chamber, the freezing chamber includes a chamber body and a cover body, the chamber body has an opening, and the cover body is used to open or close the opening, and the carrier has a storage position for storing the first container; the housing cover has an installation space, an air inlet duct, and an air outlet duct, the fan is accommodated in the installation space, the installation space intakes air through the air inlet duct and discharges air through the air outlet duct, the air outlet duct is used to direct the air flow generated by the fan to the storage position, and the directions of the air inlet duct and the air outlet duct are different; a first dispensing mechanism for adding the quality control product / calibration product in the first container retrieved from the freezing chamber to the corresponding reaction container; the detection device is further used to detect a mixture containing the quality control product / calibration product and the reagent in the reaction container to obtain a quality control / calibration detection result.

2. The sample analyzer according to claim 1, characterized in that, one of the air outlet duct and the air inlet duct is arranged in the vertical direction, and the other is arranged in the horizontal direction.

3. The sample analyzer according to claim 1, characterized in that, the fan is arranged on the cover body, the fan is located above the carrier, and the air outlet duct faces the side where the bottom surface of the chamber body is located.

4. The sample analyzer according to claim 3, characterized in that, the housing cover has a bottom housing wall facing the side where the bottom surface of the chamber body is located, and the air outlet duct is arranged on the bottom housing wall; and / or, the housing cover has a peripheral housing wall surrounding the circumference of the fan, and the air inlet duct is arranged on the peripheral housing wall.

5. The sample analyzer according to claim 1, characterized in that, the fan is arranged on the cover body; the freezing chamber device further includes a grille structure that defines an accommodation space, the carrier is located in the accommodation space, the fan is used to blow air towards the accommodation space, and the grille structure enables air communication between the accommodation space and the inner surface of the chamber body.

6. The sample analyzer according to claim 5, characterized in that, at least a part of the outer peripheral surface of the grille structure is spaced from the inner surface on the circumferential side of the chamber body and defines a first cavity surrounding the outer periphery of the grille structure.

7. The sample analyzer according to claim 5, wherein, the grid structure includes a plurality of grid bars, the grid bars extend in the horizontal direction, and the plurality of grid bars are arranged at intervals in the height direction.

8. The sample analyzer according to claim 1, wherein, the carrier includes a support base and a limiting frame, the limiting frame is located above the support base, the limiting frame has at least one limiting channel for accommodating the first container, and the support base is used for supporting the bottom of the first container.

9. The sample analyzer according to claim 8, wherein, the support base has ventilation holes, and the ventilation holes enable air communication between the space above the support base and the bottom surface of the chamber body.

10. The sample analyzer according to claim 9, wherein, at least part of the support base is spaced apart from the bottom surface of the chamber body and defines a second cavity.

11. The sample analyzer according to claim 8, wherein, the limiting frame has at least one through hole, the through hole communicates with the corresponding limiting channel, and the through hole enables air communication between the spaces on the upper and lower opposite sides of the limiting frame.

12. The sample analyzer according to claim 11, wherein, the limiting frame includes a plate body and at least one group of limiting pieces arranged on the bottom side of the plate body, the plate body is provided with through holes, each group of limiting pieces includes at least two limiting pieces, each group of limiting pieces is arranged at the edge of the bottom side of the corresponding through hole, the top end of the limiting piece is connected to the plate body, the bottom end of the limiting piece is a free end, and each group of limiting pieces defines the limiting channel.

13. The sample analyzer according to any one of claims 1-12, wherein, the sample analyzer includes a transfer mechanism and a controller, and the controller is used to control the transfer mechanism to move the first container out of the freezing chamber and transfer it to the liquid suction position of the first dispensing mechanism for liquid suction to perform quality control / calibration tests.

14. The sample analyzer according to any one of claims 1-12, wherein, the sample analyzer includes a driving mechanism and a controller, the driving mechanism is connected to the cover body, and the controller is further used to: control the movement of the driving mechanism to drive the cover body to open the cover and / or close the cover through the driving mechanism.

15. The sample analyzer according to any one of claims 1-14, wherein, the sample analyzer includes a controller, and the controller is used to: after the cover body closes the cover, control the fan to rotate.

16. The sample analyzer according to any one of claims 1-15, wherein, the sample analyzer includes a controller, and the controller is further used to: when the cover body opens the cover, control the fan to remain closed.

17. The sample analyzer according to claim 15, wherein, The sample analyzer includes a detection module configured to detect environmental parameters outside the freezing chamber and obtain environmental parameter information, where the environmental parameters include at least one of temperature and humidity. The controller is configured to control the rotation duration of the fan according to the environmental parameter information; and / or, The sample analyzer includes a timing module configured to record the time of a single lid opening, and the controller is configured to control the rotation duration of the fan according to the time of a single lid opening.

18. A storage module, characterized in that, it includes: A freezing chamber, a fan, a housing cover, and a carrier for carrying a first container, where the first container is used to store quality control products / calibration products, the freezing chamber is used to provide a refrigeration environment below zero degrees, the carrier and the fan are both arranged inside the freezing chamber, the freezing chamber includes a chamber body and a cover body, the chamber body has an opening, and the cover body is used to open or close the opening, and the carrier has a storage position for storing the first container; The housing cover has an installation space, an air inlet duct, and an air outlet duct. The fan is accommodated in the installation space. The installation space intakes air through the air inlet duct and discharges air through the air outlet duct. The air outlet duct is used to direct the airflow generated by the fan to the storage position, and the directions of the air inlet duct and the air outlet duct are different.

19. The storage module according to claim 18, characterized in that, The storage module includes a controller configured to control the fan to rotate after the cover body is closed; and / or, The storage module includes a driving mechanism, and the controller is further configured to control the movement of the driving mechanism to drive the cover body to open or close through the driving mechanism.

20. An analysis system, characterized in that, it includes an analyzer, a transfer mechanism, and the storage module according to claim 18 or 19. The transfer mechanism is used to transfer the first container in the freezing chamber to the analyzer for quality control / calibration testing by the analyzer; wherein, the analyzer includes: A sample supply mechanism for carrying a sample container containing a sample to be measured; A reagent supply mechanism for carrying a reagent container containing a reagent; A sample dispensing mechanism for adding the sample to a reaction container; A reagent dispensing mechanism for adding the reagent in the reagent chamber to the corresponding reaction container; A detection device for detecting a reaction solution containing the sample and the reagent in the reaction container to obtain a sample detection result; A first dispensing mechanism for adding the quality control product / calibration product in the first container retrieved from the freezing chamber to the corresponding reaction container; The detection device is further configured to detect a mixed solution containing the quality control product / calibration product and the reagent in the reaction container to obtain a quality control / calibration detection result.

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