Traditional Chinese medicine for treating atrophic gastritis caused by qi stagnation of liver and stomach

Abstract

A traditional Chinese medicine for treating liver-stomach qi stagnation type atrophic gastritis can effectively solve the medication problem of the liver-stomach qi stagnation type atrophic gastritis, and is prepared from the following traditional Chinese medicine raw materials: fructus aurantii, mangnolia officinalis, fingered citron, betel nut, scutellaria baicalensis, coptis chinensis, hairyvein agrimony, sculellaria barbata, curcuma zedoary, oldenlandia diffusa, lucid ganoderma and liquorice. Decocting with slow fire, and filtering to obtain a first filtrate; adding water into filter residues, boiling with strong fire, decocting with slow fire to obtain a second filtrate, combining the filtrates, uniformly mixing and concentrating to obtain a finished product. The traditional Chinese medicine is matched and mutually supported according to the primary and secondary relationship of monarch, minister, assistant and guide, is scientifically prepared, has the effects of soothing liver and harmonizing stomach, promoting diuresis, reducing phlegm and activating blood stasis, is convenient to take and good in effect, is a new breakthrough in the medicine for treating the liver-stomach qi stagnation type atrophic gastritis, and has huge economic and social benefits.

Description

Technical Field

[0001] The present invention relates to traditional Chinese medicine, and in particular to a traditional Chinese medicine for treating atrophic gastritis of liver-stomach qi stagnation type. Background Art

[0002] Chronic atrophic gastritis (CAG) is a relatively common digestive system inflammatory disease in clinical practice. Its main pathological changes are the atrophy and reduction of the number of gastric mucosal glands and the thinning of the mucosal layer, accompanied by or without intestinal metaplasia and dysplasia. Its incidence is mainly related to the chronic infection of Helicobacter Pylori (HP), and CAG combined with HP infection has a 6.4 - 11.8 times higher possibility of developing into gastric cancer. It is a precancerous disease, and actively preventing canceration is of great significance.

[0003] In the current Western medicine treatment plan, it mainly focuses on symptomatic treatment, including eradicating HP, enhancing gastric motility, inhibiting gastric acid, protecting the gastric mucosa, and using multiple drugs in combination. Secondly, a reasonable diet with a combination of meat and vegetables and maintaining an optimistic attitude can be adopted to assist in enhancing gastric function. Although the effect is obvious, the drug adverse reactions are large, the effect of radical cure of HP is poor, and after long-term antibiotic treatment, the recurrence of the disease is likely to occur due to the drug resistance of HP, bringing many problems to the treatment of the disease.

[0004] There is no disease name of atrophic gastritis in traditional Chinese medical ancient books. Its main clinical manifestations are abdominal distension, dull pain, acid regurgitation, hiccups, weight loss, and loss of appetite in the upper abdomen. This disease is closely related to emotional disharmony. Emotional discomfort leads to liver qi stagnation. The transportation and transformation functions of the spleen and stomach must be dredged by the liver wood. Therefore, "Huangdi Neijing" says: "The earth is dredged by the wood." "Clinical Guide to Medical Records" says: "The wood can dredge the earth and the stagnation of the spleen can be relieved." If the liver and stomach qi stagnate, the liver wood invades the spleen earth, and the spleen and stomach lose their health, resulting in qi stagnation, food retention, dampness (phlegm) obstruction, cold coagulation, fire stagnation, blood stasis, etc. Over time, it leads to atrophic gastritis. The main symptom of the patient is abdominal distension. If the patient has a long illness, dampness will be generated. The dampness blocks qi movement, so intermittent abdominal distension and flatulence are seen; over time, it turns into heat and descends to the intestines and bladder, so a feeling of incomplete defecation and frequent urination are seen; the tongue is pale red, the tongue coating is yellow and greasy, and the pulse is deep and slippery.

[0005] To sum up, the stagnation of liver and stomach qi, and the long-term obstruction of dampness, heat, phlegm, and blood stasis are the pathogenesis of atrophic gastritis. Based on the above theory, developing a new drug for treating atrophic gastritis through the principle of soothing the liver and regulating the stomach is a new technical idea, but there has been no public report so far. Summary of the Invention

[0006] In view of the above situation, to overcome the deficiencies of the prior art, the purpose of the present invention is to provide a traditional Chinese medicine for treating atrophic gastritis of liver-stomach qi stagnation type, which can effectively solve the problem of medication for treating atrophic gastritis of liver-stomach qi stagnation type.

[0007] The technical solution solved by the present invention is a traditional Chinese medicine for treating atrophic gastritis of liver-stomach qi stagnation type, which is made from the following traditional Chinese medicine raw materials by weight: Fructus Aurantii 15 - 20g, Magnolia officinalis 15 - 20g, Citrus medica var. sarcodactylis 10 - 15g, Areca catechu 15 - 20g, Scutellaria baicalensis 10 - 12g, Coptis chinensis 10 - 12g, Agrimonia pilosa 15 - 20g, Scutellaria barbata 10 - 15g, Rhizoma Curcumae 6 - 8g, Hedyotis diffusa 15 - 30g, Ganoderma lucidum 12 - 15g, and Glycyrrhiza uralensis 3 - 5g. Add 400 - 600 ml of water to the above traditional Chinese medicine raw materials, soak at room temperature for 15 - 25 minutes, then bring to a boil over high heat, and then turn to low heat and decoct for 20 - 30 minutes, filter to obtain the first filtrate; add 300 - 400 ml of water to the residue, bring to a boil over high heat, then turn to low heat and decoct for 10 - 15 minutes to obtain the second filtrate. Combine the two filtrates and mix well and concentrate to 1 / 2 - 1 / 3 of the total water added twice, which is the finished traditional Chinese medicine decoction.

[0008] The traditional Chinese medicine of the present invention is formulated according to the primary and secondary relationships of monarch, minister, assistant, and envoy, supporting each other. After scientific preparation, it has the functions of soothing the liver and regulating the stomach, promoting diuresis to resolve phlegm, activating blood circulation and removing stasis. It is convenient to use and has good effects. It is a new breakthrough in the treatment of atrophic gastritis of liver-stomach qi stagnation type, with great economic and social benefits. Detailed implementation mode

[0009] The following will explain in detail the specific implementation mode of the present invention in combination with examples and specific situations.

[0010] Example 1:

[0011] A traditional Chinese medicine for treating atrophic gastritis of liver-stomach qi stagnation type is made from the following traditional Chinese medicine raw materials by weight: Fructus Aurantii 20g, Magnolia officinalis 15g, Citrus medica var. sarcodactylis 15g, Areca catechu 15g, Scutellaria baicalensis 10g, Coptis chinensis 10g, Agrimonia pilosa 15g, Scutellaria barbata 15g, Rhizoma Curcumae 6g, Hedyotis diffusa 15g, Ganoderma lucidum 12g, and Glycyrrhiza uralensis 5g. Add 400 - 600 ml of water to the above traditional Chinese medicine raw materials, soak at room temperature for 15 - 25 minutes, then bring to a boil over high heat, and then turn to low heat and decoct for 20 - 30 minutes, filter to obtain the first filtrate; add 300 - 400 ml of water to the residue, bring to a boil over high heat, then turn to low heat and decoct for 10 - 15 minutes, filter to obtain the second filtrate. Combine the two filtrates and mix well to 1 / 2 - 1 / 3 of the total water added twice, which is the finished traditional Chinese medicine decoction.

[0012] Example 2:

[0013] A traditional Chinese medicine for treating atrophic gastritis of liver-stomach qi stagnation type is made from the following traditional Chinese medicine raw materials by weight: 17g of Fructus Aurantii, 18g of Magnolia officinalis, 12g of Fructus Citri Sarcodactylis, 13g of Areca catechu L., 11g of Scutellaria baicalensis Georgi, 11g of Coptis chinensis Franch., 17g of Agrimonia pilosa Ledeb., 13g of Scutellaria barbata D. Don, 7g of Rhizoma Curcumae, 18g of Hedyotis diffusa Willd., 13g of Ganoderma lucidum and 4g of Glycyrrhiza uralensis Fisch. The above traditional Chinese medicine raw materials are added with 500 ml of water, soaked at room temperature for 20 minutes, then brought to a boil over high heat and then turned to low heat and decocted for 25 minutes, filtered to obtain the first filtrate; the filter residue is added with 350 ml of water, brought to a boil over high heat and then turned to low heat and decocted for 13 minutes, filtered to obtain the second filtrate, and the two filtrates are combined and mixed to 40% of the total water addition amount, which is the finished traditional Chinese medicine decoction.

[0014] Example 3:

[0015] A traditional Chinese medicine for treating atrophic gastritis of liver-stomach qi stagnation type is made from the following traditional Chinese medicine raw materials by weight: 15g of Fructus Aurantii, 15g of Magnolia officinalis, 10g of Fructus Citri Sarcodactylis, 15g of Areca catechu L., 10g of Scutellaria baicalensis Georgi, 10g of Coptis chinensis Franch., 15g of Agrimonia pilosa Ledeb., 10g of Scutellaria barbata D. Don, 6g of Rhizoma Curcumae, 15g of Hedyotis diffusa Willd., 12g of Ganoderma lucidum and 3g of Glycyrrhiza uralensis Fisch. The above traditional Chinese medicine raw materials are added with 400 ml of water, soaked at room temperature for 15 minutes, then brought to a boil over high heat and then turned to low heat and decocted for 20 minutes, filtered to obtain the first filtrate; the filter residue is added with 300 ml of water, brought to a boil over high heat and then turned to low heat and decocted for 10 minutes, filtered to obtain the second filtrate, and the two filtrates are combined and mixed to 1 / 2 of the total water addition amount, which is the finished traditional Chinese medicine decoction.

[0016] Example 4:

[0017] A traditional Chinese medicine for treating atrophic gastritis of liver-stomach qi stagnation type is made from the following traditional Chinese medicine raw materials by weight: 20g of Fructus Aurantii, 20g of Magnolia officinalis, 15g of Fructus Citri Sarcodactylis, 20g of Areca catechu L., 12g of Scutellaria baicalensis Georgi, 12g of Coptis chinensis Franch., 20g of Agrimonia pilosa Ledeb., 15g of Scutellaria barbata D. Don, 8g of Rhizoma Curcumae, 30g of Hedyotis diffusa Willd., 15g of Ganoderma lucidum and 5g of Glycyrrhiza uralensis Fisch. The above traditional Chinese medicine raw materials are added with 600 ml of water, soaked at room temperature for 25 minutes, then brought to a boil over high heat and then turned to low heat and decocted for 30 minutes, filtered to obtain the first filtrate; the filter residue is added with 400 ml of water, brought to a boil over high heat and then turned to low heat and decocted for 15 minutes, filtered to obtain the second filtrate, and the two filtrates are combined and mixed to 1 / 3 of the total water addition amount, which is the finished traditional Chinese medicine decoction.

[0018] Example 5:

[0019] A traditional Chinese medicine for treating atrophic gastritis of liver-stomach qi stagnation type is prepared from the following traditional Chinese medicine raw materials by weight: 15 g of Fructus Aurantii, 20 g of Magnolia officinalis, 10 g of Citrus medica var. sarcodactylis, 20 g of Areca catechu, 10 g of Scutellaria baicalensis, 12 g of Coptis chinensis, 15 g of Agrimonia pilosa, 15 g of Scutellaria barbata, 6 g of Rhizoma Curcumae, 30 g of Hedyotis diffusa, 12 g of Ganoderma lucidum, and 5 g of Glycyrrhiza uralensis. Add 400 ml of water to the above traditional Chinese medicine raw materials, soak at room temperature for 15 minutes, then bring to a boil over high heat, and then turn to low heat and decoct for 30 minutes. Filter to obtain the first filtrate; add 400 ml of water to the filter residue, bring to a boil over high heat, then turn to low heat and decoct for 10 minutes. Filter to obtain the second filtrate. Combine the two filtrates and mix them evenly to 1 / 3 of the total amount of water added twice, which is the finished traditional Chinese medicine decoction.

[0020] Example 6:

[0021] A traditional Chinese medicine for treating atrophic gastritis of liver-stomach qi stagnation type is prepared from the following traditional Chinese medicine raw materials by weight: 20 g of Fructus Aurantii, 15 g of Magnolia officinalis, 15 g of Citrus medica var. sarcodactylis, 15 g of Areca catechu, 12 g of Scutellaria baicalensis, 10 g of Coptis chinensis, 20 g of Agrimonia pilosa, 10 g of Scutellaria barbata, 8 g of Rhizoma Curcumae, 15 g of Hedyotis diffusa, 15 g of Ganoderma lucidum, and 3 g of Glycyrrhiza uralensis. Add 600 ml of water to the above traditional Chinese medicine raw materials, soak at room temperature for 25 minutes, then bring to a boil over high heat, and then turn to low heat and decoct for 20 minutes. Filter to obtain the first filtrate; add 300 ml of water to the filter residue, bring to a boil over high heat, then turn to low heat and decoct for 15 minutes. Filter to obtain the second filtrate. Combine the two filtrates and mix them evenly to 1 / 2 of the total amount of water added twice, which is the finished traditional Chinese medicine decoction.

[0022] According to the composition given in the above examples, any amount of traditional Chinese medicine can be prepared as needed. The examples given are only used to illustrate the specific implementation manners of the present invention, rather than to limit the protection scope of the present invention. The core and key technology protected by the present invention is the compatibility of the traditional Chinese medicine composition.

[0023] Among the above-mentioned raw materials of the medicinal drugs, where:

[0024] Fructus Aurantii: Slightly cold in nature, bitter and pungent in taste, belonging to the spleen, stomach, and large intestine meridians. Promoting qi circulation to relieve distension, eliminating fullness and distension.

[0025] Magnolia officinalis: Warm in nature, bitter and pungent in taste, belonging to the spleen, stomach, lung, and large intestine meridians. Promoting qi circulation to eliminate fullness, drying dampness and resolving phlegm.

[0026] Citrus medica var. sarcodactylis: Warm in nature, pungent, bitter, and sour in taste, belonging to the liver, spleen, stomach, and lung meridians. Soothing the liver and regulating qi, harmonizing the stomach and relieving pain, resolving phlegm and relieving cough.

[0027] Areca catechu: Warm in nature, bitter and pungent in taste, belonging to the stomach and large intestine meridians. Expelling worms and relieving accumulation, promoting qi circulation and promoting diuresis.

[0028] Scutellaria baicalensis: Cold in nature, bitter in taste, belonging to the lung, gallbladder, spleen, stomach, large intestine, and small intestine meridians. Clearing heat and drying dampness, purging fire and detoxifying, stopping bleeding and preventing miscarriage.

[0029] Coptis chinensis: Cold in nature, bitter in taste, attributing to the heart, spleen, stomach, liver, gallbladder, and large intestine meridians. It clears heat and dries dampness, purges fire and detoxifies.

[0030] Agrimony: Neutral in nature, bitter and astringent in taste, attributing to the lung, liver, and spleen meridians. It astringes to stop bleeding, detoxifies and reduces swelling.

[0031] Scutellaria barbata: Cold in nature, pungent and bitter in taste, attributing to the lung, liver, and kidney meridians. It clears heat and detoxifies, promotes blood circulation to remove stasis and induces diuresis.

[0032] Zedoary: Warm in nature, pungent and bitter in taste, attributing to the liver and spleen meridians. It promotes qi circulation to break blood stasis, eliminates accumulation and relieves pain.

[0033] Oldenlandia diffusa: Cool in nature, sweet and light in taste, attributing to the stomach, large intestine, and small intestine meridians. It clears heat and detoxifies, promotes diuresis and relieves stranguria.

[0034] Ganoderma lucidum: Neutral in nature, sweet in taste, attributing to the heart, lung, liver, and kidney meridians. It supplements qi and soothes the nerves, relieves cough and asthma.

[0035] Licorice: Neutral in nature, sweet in taste, attributing to the heart, lung, spleen, and stomach meridians. It invigorates the spleen and replenishes qi, clears heat and detoxifies, reduces phlegm and relieves cough, alleviates spasm and pain.

[0036] The above-mentioned drugs are effectively combined according to the primary and secondary relationship of monarch, minister, assistant, and guide, support each other, and are scientifically prepared, having the effects of soothing the liver and regulating the stomach, promoting diuresis, resolving phlegm, and activating blood circulation and removing stasis. In the formula:

[0037] Fructus Aurantii Immaturus and Magnolia officinalis promote qi circulation to relieve distension, dry dampness and resolve phlegm, Citrus medica var. sarcodactylis regulates the stomach and promotes qi circulation, and Areca catechu promotes qi circulation to eliminate accumulation, altogether serving as the monarch drugs, regulating qi and promoting smoothness in the middle energizer, and concurrently resolving phlegm-dampness; Scutellaria baicalensis, Coptis chinensis, and Agrimony clear heat and transform dampness, altogether serving as the minister drugs; Scutellaria barbata, Zedoary, and Oldenlandia diffusa promote blood circulation to remove stasis and dissipate masses, and Ganoderma lucidum strengthens the healthy qi and expels pathogenic factors, altogether serving as the assistant drugs; Licorice harmonizes all the drugs and serves as the guide drug. The whole formula jointly exerts the effects of soothing the liver and regulating the stomach, resolving dampness and removing stasis, can be effectively used for treating atrophic gastritis of liver-stomach qi stagnation type, and is the experimental drug for treating precancerous lesions such as intestinal metaplasia of atrophic gastritis, and has achieved very good beneficial technical effects through experiments. The relevant experimental data are as follows (taking Example 1 as an example):

[0038] I. Source of cases

[0039] The cases in this experiment were selected from 60 inpatients with atrophic gastritis of liver-stomach qi stagnation type from January 2021 to October 2024 as the source of cases.

[0040] II. Diagnostic criteria

[0041] 1. Diagnostic criteria for atrophic gastritis (CAG)

[0042] (1) Clinical manifestations:

[0043] ① The typical clinical symptoms of CAG are fullness, pain and discomfort, located in the epigastric region, and may be accompanied by loss of appetite, acid regurgitation, and a feeling of discomfort in the stomach.

[0044] ② Most of the time there are no obvious signs, but sometimes there may be discomfort when pressing. Physical examination: positive abdominal tenderness;

[0045] ③A small number of patients have extra-gastrointestinal manifestations, such as weight loss, anemia, or psychological and mental problems.

[0046] (2) Endoscopic examination:

[0047] ① Microscopic manifestations: The gastric mucosa is red and white, the folds are flat or even disappeared, and mucosal blood vessels and mucosal granules can be seen.

[0048] ②It can be combined with magnifying endoscopy, laser confocal microendoscopy, optical biopsy and other examinations.

[0049] (3) Histological examination of gastric mucosa (pathological diagnosis)

[0050] Combined with the visual analogue scale, CAG pathology showed:

[0051] The gastric mucosal glandular atrophy or intestinal metaplasia is repeated or multiple to assess the extent and severity.

[0052] 2. TCM diagnostic criteria

[0053] Refer to the "Guidelines for Clinical Research of New Chinese Medicines (Trial)" and combine clinical practice to formulate:

[0054] Liver-stomach Qi stagnation syndrome

[0055] Main symptoms: stomach discomfort, distension or pain involving the ribs;

[0056] Secondary symptoms: mostly related to emotional factors; frequent belching.

[0057] III. Inclusion criteria:

[0058] 1) Those who meet the diagnosis of CAG and have not received treatment;

[0059] 2) Age: 18-65 years old.

[0060] IV. Exclusion criteria:

[0061] 1) Pregnant or lactating women, or those who are intolerant to the medication used in this trial;

[0062] 2) Those who have serious cardiovascular and cerebrovascular diseases, liver and kidney diseases, serious mental illnesses or intellectual disabilities and are unable to cooperate;

[0063] 3) Unable to tolerate gastroscopy

[0064] 5. Case Grouping:

[0065] Sixty patients with atrophic gastritis (liver-stomach qi stagnation type) who were hospitalized from January 2021 to October 2024 were divided into a treatment group and a control group according to a random number table, with 30 patients in each group.

[0066] VI. Treatment plan:

[0067] Control group: Morodan (16 pills × 18 bags, national drug approval number Z20090013, Handan Pharmaceutical Co., Ltd.), taken orally three times a day, once after breakfast, lunch, and dinner, 16 pills each time. The curative effect was statistically analyzed after 4 weeks;

[0068] Treatment group: The traditional Chinese medicine of the present invention was taken orally three times a day, once after breakfast, lunch, and dinner, 100 - 150 ml each time. The curative effect was statistically analyzed after four weeks.

[0069] VII. Curative effect evaluation criteria

[0070] The scoring criteria in Table 1 were adopted, and the following formula was used to judge the curative effect:

[0071] Curative effect determination value = (pre-treatment score - post-treatment score) / pre-treatment score × 100%;

[0072] Table 1 Scoring criteria

[0073]

[0074]

[0075] The curative effect evaluation criteria are as follows:

[0076] Marked effect: determination value > 2 / 3;

[0077] Effective: 1 / 3 < determination value < 2 / 3;

[0078] Ineffective: determination value < 1 / 3.

[0079] VIII. Statistical analysis of clinical curative effect

[0080] After statistics, in the treatment group, 16 cases had a marked effect, 11 cases were effective, and 3 cases were ineffective, with a total effective rate of 90%. In the control group, 7 cases had a marked effect, 17 cases were effective, and 6 cases were ineffective, with a total effective rate of 80%. After testing, ▲ P < 0.05, and the difference between the two groups was statistically significant. The curative effect of the treatment group was significantly better than that of the control group, as shown in Table 2.

[0081] Table 2 Clinical curative effect evaluation [n(%)]

[0082] Group Number of cases Marked effect Effective Ineffective Total effective rate Treatment group 30 16(53.33％) 11(36.67％) 3(10％) 90％ Control group 30 7(23.33％) 17(56.67％) 6(20％) 80％

[0083] While conducting experiments on Example 1, clinical experiments were also carried out on other examples, and the same or similar results were obtained. They are not listed one by one here.

[0084] IX. Conclusion

[0085] As can be seen from the above, the raw materials of the present invention are rich, the preparation method is simple, it is easy to take, the cost is low, and the effect is good. The components support each other according to the primary and secondary relationship of monarch, minister, assistant and guide, and have the effects of soothing the liver and regulating the stomach, resolving dampness and removing stasis. The whole prescription not only has stable curative effect, but also has good long-term curative effect, is not easy to relapse, is easily accepted by patients, and has an effective rate as high as 90%. It is effectively used for the treatment of atrophic gastritis of liver-stomach qi stagnation type. The Weikang Decoction of the present invention, characterized by simplicity, convenience, low cost and effectiveness, not only conforms to the pathogenesis law of atrophic gastritis, but also conforms to the traditional Chinese medicine theory. It is an innovation in the medicine for the treatment of atrophic gastritis and has huge economic and social benefits.

Claims

1. A Chinese medicine for treating atrophic gastritis of liver-stomach qi stagnation type, which is prepared from the following Chinese medicine raw materials by weight: 15-20g of Citrus aurantium, 15-20g of Magnolia officinalis, 10-15g of Citron, 15-20g of Areca catechu, 10-12g of Scutellaria baicalensis, 10-12g of Coptis chinensis, 15-20g of Agrimoniae, 10-15g of Scutellaria barbata, 6-8g of Curcuma zedoaria, 15-30g of Hedyotis diffusa, 12-15g of Ganoderma lucidum and 3-5g of Licorice, The above-mentioned Chinese medicinal raw materials are added with 400-600 ml of water, soaked at room temperature for 15-25 minutes, then boiled over high heat, then simmered over low heat, decocted for 20-30 minutes, and filtered to obtain the first filtrate; the filter residue is added with 300-400 ml of water, boiled over high heat, then simmered over low heat, decocted for 10-15 minutes to obtain the second filtrate, the two filtrates are combined, mixed and concentrated to 1 / 2 to 1 / 3 of the amount of water added twice, which is the finished Chinese medicinal decoction.

2. The Chinese medicine for treating liver-stomach qi stagnation type atrophic gastritis according to claim 1, characterized in that: The method is prepared from the following Chinese medicinal raw materials by weight: 20g of Fructus Aurantii Immaturus, 15g of Magnolia officinalis, 15g of Citron, 15g of Areca Nut, 10g of Scutellaria Baicalensis, 10g of Coptis Chinensis, 15g of Herba Agrimoniae, 15g of Scutellariae Scutellariae, 6g of Curcuma Atractylodes, 15g of Hedyotis Diffusa, 12g of Ganoderma Lucidum and 5g of Licorice. 400-600ml of water is added to the above Chinese medicinal raw materials, and the mixture is soaked at room temperature for 15-25 minutes, and then boiled over high heat, and then decocted over low heat for 20-30 minutes, and filtered to obtain a first filtrate. 300-400ml of water is added to the filter residue, and after boiling over high heat, the mixture is decocted over low heat for 10-15 minutes, and filtered to obtain a second filtrate. The two filtrates are combined and mixed to 1 / 2 to 1 / 3 of the amount of water added twice to obtain a finished Chinese medicinal decoction.

3. The Chinese medicine for treating liver-stomach qi stagnation type atrophic gastritis according to claim 1, characterized in that: The method is prepared from the following Chinese medicinal raw materials by weight: 17g of Fructus Aurantii Immaturus, 18g of Magnolia officinalis, 12g of Citron, 13g of Areca Nut, 11g of Scutellaria Baicalensis, 11g of Coptis Chinensis, 17g of Herba Agrimoniae, 13g of Scutellariae Scutellariae, 7g of Curcuma Atractylodes, 18g of Hedyotis Diffusa, 13g of Ganoderma Lucidum and 4g of Licorice. 500ml of water is added to the above Chinese medicinal raw materials, and the mixture is soaked at room temperature for 20 minutes, then boiled over high heat, then reduced to low heat, decocted for 25 minutes, and filtered to obtain a first filtrate. 350ml of water is added to the filter residue, and the mixture is boiled over high heat, then reduced to low heat, decocted for 13 minutes, and filtered to obtain a second filtrate. The two filtrates are combined and mixed to 40% of the amount of water added twice to obtain a finished Chinese medicinal decoction.

4. The Chinese medicine for treating liver-stomach qi stagnation type atrophic gastritis according to claim 1, characterized in that: The method is prepared from the following Chinese medicinal raw materials by weight: 15g of Citrus aurantium, 15g of Magnolia officinalis, 10g of Citron, 15g of Areca catechu, 10g of Scutellaria baicalensis, 10g of Coptis chinensis, 15g of Herba Agrimoniae, 10g of Scutellaria barbata, 6g of Curcuma zedoaria, 15g of Hedyotis diffusa, 12g of Ganoderma lucidum and 3g of Licorice. 400ml of water is added to the above Chinese medicinal raw materials, and the mixture is soaked at room temperature for 15 minutes, then boiled over high heat, then reduced to low heat, decocted for 20 minutes, and filtered to obtain a first filtrate. 300ml of water is added to the filter residue, and the mixture is boiled over high heat, then reduced to low heat, decocted for 10 minutes, and filtered to obtain a second filtrate. The two filtrates are combined and mixed to 1 / 2 of the amount of water added twice to obtain a finished Chinese medicinal decoction.

5. The Chinese medicine for treating liver-stomach qi stagnation type atrophic gastritis according to claim 1, characterized in that: The method is prepared from the following Chinese medicinal raw materials by weight: 20g of Citrus aurantium, 20g of Magnolia officinalis, 15g of Citron, 20g of Areca catechu, 12g of Scutellaria baicalensis, 12g of Coptis chinensis, 20g of Herba Agrimoniae, 15g of Scutellaria barbata, 8g of Curcuma zedoaria, 30g of Hedyotis diffusa, 15g of Ganoderma lucidum and 5g of Licorice. 600ml of water is added to the above Chinese medicinal raw materials, and the mixture is soaked at room temperature for 25 minutes, then boiled over high heat, then reduced to low heat, decocted for 30 minutes, and filtered to obtain a first filtrate. 400ml of water is added to the filter residue, and the mixture is boiled over high heat, then reduced to low heat, decocted for 15 minutes, and filtered to obtain a second filtrate. The two filtrates are combined and mixed to 1 / 3 of the amount of water added twice to obtain a finished Chinese medicinal decoction.

6. The Chinese medicine for treating liver-stomach qi stagnation type atrophic gastritis according to claim 1, characterized in that: The method is prepared from the following Chinese medicinal raw materials by weight: 15g of Fructus Aurantii Immaturus, 20g of Magnolia officinalis, 10g of Citron, 20g of Areca Nut, 10g of Scutellaria Baicalensis, 12g of Coptis Chinensis, 15g of Herba Agrimoniae, 15g of Scutellariae Scutellariae, 6g of Curcuma Atractylodes, 30g of Hedyotis Diffusa, 12g of Ganoderma Lucidum and 5g of Licorice. 400ml of water is added to the above Chinese medicinal raw materials, and the mixture is soaked at room temperature for 15 minutes, then boiled over high heat, then reduced to low heat, decocted for 30 minutes, and filtered to obtain a first filtrate. 400ml of water is added to the filter residue, and the mixture is boiled over high heat, then reduced to low heat, decocted for 10 minutes, and filtered to obtain a second filtrate. The two filtrates are combined and mixed to 1 / 3 of the amount of water added twice to obtain a finished Chinese medicinal decoction.

7. The Chinese medicine for treating liver-stomach qi stagnation type atrophic gastritis according to claim 1, characterized in that: The method is prepared from the following Chinese medicinal raw materials by weight: 20g of Citrus aurantium, 15g of Magnolia officinalis, 15g of Citron, 15g of Areca catechu, 12g of Scutellaria baicalensis, 10g of Coptis chinensis, 20g of Agrimoniae, 10g of Scutellaria barbata, 8g of Curcuma zedoaria, 15g of Hedyotis diffusa, 15g of Ganoderma lucidum and 3g of Licorice. 600ml of water is added to the above Chinese medicinal raw materials, and the mixture is soaked at room temperature for 25 minutes, then boiled over high heat, then reduced to low heat, decocted for 20 minutes, and filtered to obtain a first filtrate; 300ml of water is added to the filter residue, and the mixture is boiled over high heat, then reduced to low heat, decocted for 15 minutes, and filtered to obtain a second filtrate. The two filtrates are combined and mixed to 1 / 2 of the amount of water added twice to obtain a finished Chinese medicinal decoction.

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