Multifunctional broad-spectrum powerful decontamination agent and preparation method thereof

Abstract

The invention relates to the field of decontamination agents, and provides a multifunctional broad-spectrum powerful decontamination agent and a preparation method thereof.The decontamination agent comprises a component A, a component B and a component C; the component A is prepared from the following raw materials in parts by weight: 0.3 to 0.7 part of benzalkonium chloride, 1 to 3 parts of polyethylene glycol, 0.2 to 0.6 part of fatty alcohol, 0.5 to 1 part of diethylene glycol monobutyl ether, 10 to 15 parts of a solvent, 4.5 to 5 parts of potassium bicarbonate, 0.5 to 1.3 parts of a foaming promoting stabilizer and 0.5 to 2 parts of an anticorrosive agent; the component B is a hydrogen peroxide aqueous solution; and the component C is glyceryl diacetate. The decontamination agent provided by the invention has chemical removal and biological disinfection functions and has the characteristics of good foaming performance and foam stability.

Description

Technical Field

[0001] The invention relates to the field of cleaning agents, and in particular to a multifunctional, broad-spectrum and powerful cleaning agent and a preparation method thereof. Background Art

[0002] Decontamination agents, also known as disinfectants, are mainly used to eliminate toxic and harmful hazardous chemicals through physical, chemical and biological effects. They can be used to remove toxic agents, radioactive substances and biological warfare agents from the surfaces of personnel, equipment, ground and buildings.

[0003] In addition to the basic functions of disinfectants, biochemical disinfectants also have the functions of integrating chemical elimination and biological disinfection. They can quickly and efficiently remove common industrial pollutants and toxic and hazardous chemicals, block the spread of hazards, and restore environmental safety. Therefore, it is very important to develop disinfectants that can both effectively disinfect pathogens and remove chemical toxic substances. However, even though biochemical disinfectants have many excellent characteristics mentioned above, they are mostly in the form of foam, which often has problems such as poor foaming and insufficient foam stability.

[0004] Patent CN 106345097A discloses a foam disinfectant and a preparation method thereof, wherein the foam disinfectant comprises a cationic auxiliary, an alcohol mixture, a water-soluble high molecular polymer, a cationic surfactant, a foam stabilizer and a corrosion stabilizer, etc. The foam disinfectant prepared in the application can be used in a foam state to eliminate biochemical contamination, neutralize chemical warfare agents with foam, and kill pathogenic microorganisms used as biological warfare agents, and has the advantages of high efficiency, rapidity and low corrosion. However, the foam stabilizers used in the application are dodecanol and diethylene glycol monobutyl ether, among which dodecanol is the main foam stabilizer. However, the foam of dodecanol is prone to bursting after long-term use, and its foam stabilization effect still needs to be improved.

[0005] Therefore, there is an urgent need on the market for a multifunctional, broad-spectrum, and powerful disinfectant that has both chemical removal and biological disinfection functions and has good foaming performance and foam stability. Summary of the invention

[0006] In view of the problems existing in the prior art, the present invention synthesizes a multifunctional, broad-spectrum and powerful disinfectant with three parts: component A, component B and component C, and adds a foaming promoting stabilizer to component A, which has both chemical removal and biological disinfection functions while also having good foaming performance and foam stability.

[0007] In order to achieve the above object, the technical solution adopted by the present invention is as follows:

[0008] On one hand, the present invention provides a multifunctional broad-spectrum strong disinfectant, which comprises component A, component B, and component C;

[0009] In parts by weight, the component A comprises the following raw materials: 0.3-0.7 parts of benzalkonium chloride, 1-3 parts of polyethylene glycol, 0.2-0.6 parts of fatty alcohol, 0.5-1 parts of diethylene glycol monobutyl ether, 10-15 parts of solvent, 4.5-5 parts of potassium bicarbonate, 0.5-1.3 parts of foaming promoting stabilizer, and 0.5-2 parts of anticorrosive agent;

[0010] The component B is an aqueous solution of hydrogen peroxide;

[0011] The C component is glyceryl diacetate.

[0012] In some embodiments of the present invention, the concentration of the aqueous hydrogen peroxide solution in Part B is 7.5-8.5 wt %.

[0013] Preferably, the concentration of the aqueous hydrogen peroxide solution in part B is 7.9 wt %.

[0014] In some embodiments of the present invention, based on 100 wt%, the decontamination agent includes component A in an amount of 47-51 wt%, component B in an amount of 47-51 wt%, and component C in an amount of 1-3 wt%.

[0015] The applicant uses part A composed of a surfactant as the main component, part B composed of an aqueous hydrogen peroxide solution, and diacetin, an alcohol auxiliary component C that catalyzes and promotes the combination of parts A and B, to form a multifunctional, broad-spectrum and powerful disinfection auxiliary. Components A, B, and C are mixed and stirred in sequence for use. It has the characteristics of both biological and chemical broad-spectrum disinfection, can effectively disinfect pathogenic organisms such as spores, and can effectively remove chemical toxic substances. It can also quickly and efficiently remove common industrial pollutants and toxic and harmful chemicals, block the spread of hazards, and restore environmental safety.

[0016] In some embodiments of the present invention, the fatty alcohol is lauryl alcohol.

[0017] In some embodiments of the present invention, the solvent is propylene glycol.

[0018] In some embodiments of the present invention, the method for preparing the foaming promoting stabilizer comprises the following steps:

[0019] (1) Stearic acid and xylene are mixed, heated, stirred, tetraethylenepentamine is added, the temperature is raised to 135-155° C., refluxed for 4-6 hours, and distilled under reduced pressure to obtain a solid for use;

[0020] (2) Add the solid from step (1) to the mixed solvent, stir, and introduce CO 2 , stirring to obtain the foaming promoting stabilizer.

[0021] In some embodiments of the present invention, in step (1), the mass ratio of stearic acid to tetraethylenepentamine is 1:(0.5-0.9).

[0022] In some embodiments of the present invention, the stearic acid and CO 2 The ratio is 1g:(0.7-1)L.

[0023] The disinfectant disclosed in the present application has the characteristics of both biological and chemical broad-spectrum disinfection. Currently, the products on the market can hardly have both of the above two effects. The ingredients such as benzalkonium chloride, polyethylene glycol, fatty alcohol and solvent in component A can make the disinfectant have certain foaming performance and foam stability, but the foaming performance and foam stability can not last long and still need to be improved.

[0024] The applicant uses stearic acid and tetraethylenepentamine as raw materials, and then introduces an appropriate amount of carbon dioxide to synthesize a cationic surfactant as a foaming promoting stabilizer, which has the dual functions of promoting foaming and stabilizing foam. After the carboxyl group of stearic acid and the amine group of tetraethylenepentamine undergo a dehydration reaction, the foaming promoting stabilizer has a saturated alkyl long chain, imidazoline and bicarbonate structure under the action of carbon dioxide, so that the foaming promoting stabilizer has good thermal stability, thereby slowing down the evaporation of water in the liquid film, thereby making the formed foam less likely to burst, and improving the foam stability. In addition, the structure enables the hydrophobic carbon chains to have a higher cohesive force and a larger surface viscosity, further improving the foam stability; further, the bicarbonate structure is easily decomposed to produce carbon dioxide gas, thereby promoting foaming performance; in addition, the imidazoline structure in the foaming promoting stabilizer structure enables it to have a certain corrosion resistance, and when used in combination with the quaternary ammonium salt benzalkonium chloride, it can synergistically make the disinfectant have good corrosion resistance.

[0025] In some embodiments of the present invention, the corrosion inhibitor is at least one of N,N-dimethylethanolamine, triethanolamine and dicyclohexylamine nitrite.

[0026] Another aspect of the present invention further provides a method for preparing the multifunctional broad-spectrum strong cleaning and disinfecting agent described in the above technical solution, comprising the following steps:

[0027] S1, benzalkonium chloride, polyethylene glycol, fatty alcohol, diethylene glycol monobutyl ether, solvent, potassium bicarbonate, foaming promoter stabilizer and anticorrosive agent are mixed, stirred, and pH is adjusted to 10-10.5 while stirring to obtain component A for standby use;

[0028] S2. Component A, component B and component C are sequentially mixed and stirred to obtain a multifunctional broad-spectrum and strong disinfectant.

[0029] Compared with the prior art, the present invention has the following beneficial effects:

[0030] (1) The present invention synthesizes a multifunctional broad-spectrum and strong disinfectant with components A, B and C, and adds a foaming promoting stabilizer to component A. Through the synergistic effect of the components, the multifunctional broad-spectrum and strong disinfectant has the functions of chemical removal and biological disinfection while also having the characteristics of good foaming performance and foam stability.

[0031] (2) The present invention uses stearic acid and tetraethylenepentamine as raw materials, and then introduces an appropriate amount of carbon dioxide to synthesize a cationic surfactant as a foaming promoter and stabilizer, which has the dual functions of promoting foaming and stabilizing foam, and can also synergistically make the disinfectant have good corrosion resistance.

[0032] (3) The disinfectant prepared by the present invention has both chemical removal and biological disinfection functions and has the characteristics of good foaming performance and foam stability. It can be widely used in the field of disinfectants and has good commercial application value. DETAILED DESCRIPTION

[0033] The present invention will be described below in conjunction with specific embodiments. It should be noted that the following embodiments are examples of the present invention and are only used to illustrate the present invention, but not to limit the present invention. Other combinations and various modifications within the concept of the present invention may be performed without departing from the spirit or scope of the present invention.

[0034] In the following examples and comparative examples, except for the foaming promoting stabilizer and the modified catalyst, the other compound monomers and related reagents used can be purchased from the market, wherein the polyethylene glycol is PEG 400 purchased from Hai'an Petrochemical Plant, Jiangsu Province; the CAS number of diacetin is 25395-31-7.

[0035] Preparation Example 1

[0036] The synthesis method of the foaming promoting stabilizer A comprises the following steps:

[0037] (1) Mix 14 g of stearic acid and 50 ml of xylene, heat to 100° C., stir for 30 min, add 9.5 g of tetraethylenepentamine, heat to 145° C., reflux for 5 h, and distill under reduced pressure to obtain a solid for later use;

[0038] (2) The solid from step (1) was added to a mixed solvent (30 ml of deionized water and 50 ml of ether), stirred for 1 h, and CO was introduced at 0.1 L / min. 2 2h, and stirred for 1h to obtain foaming promoting stabilizer A.

[0039] Preparation Example 2

[0040] The foaming promoting stabilizer B has the same specific implementation as the foaming promoting stabilizer A, except that in step (1), the mass of tetraethylenepentamine is replaced with 6 g.

[0041] Preparation Example 3

[0042] The foaming promoting stabilizer C has the same specific implementation as the foaming promoting stabilizer A, except that: in step (2), CO 2 The access time was replaced with 1.5h.

[0043] Example 1

[0044] A multifunctional broad-spectrum strong cleaning agent, which comprises 49 wt% of component A, 49 wt% of component B and 2 wt% of component C based on 100 wt%;

[0045] Component A includes the following raw materials by weight: 0.5 parts of benzalkonium chloride, 2 parts of polyethylene glycol, 0.4 parts of dodecanol, 0.8 parts of diethylene glycol monobutyl ether, 12.5 parts of propylene glycol, 4.7 parts of potassium bicarbonate, 0.9 parts of foaming promoter stabilizer A, and 1.2 parts of N,N-dimethylethanolamine;

[0046] Component B is 7.9wt% hydrogen peroxide aqueous solution;

[0047] Component C is glycerol diacetate.

[0048] The preparation method of the multifunctional broad-spectrum strong cleaning and disinfection agent in this embodiment comprises the following steps:

[0049] S1. Benzalkonium chloride, polyethylene glycol, dodecanol, diethylene glycol monobutyl ether, propylene glycol, potassium bicarbonate, foaming stabilizer A and N,N-dimethylethanolamine were mixed and stirred for 30 minutes. Potassium hydroxide was added while stirring to adjust the pH to 10.2 to obtain component A for standby use.

[0050] S2. Mix component A, component B and component C in sequence and stir for 1 hour to obtain a multifunctional, broad-spectrum and powerful disinfectant.

[0051] Example 2

[0052] A multifunctional broad-spectrum strong cleaning agent, which comprises 47wt% of component A, 51wt% of component B and 2wt% of component C based on 100wt%;

[0053] Component A includes the following raw materials by weight: 0.3 parts of benzalkonium chloride, 1 part of polyethylene glycol, 0.2 parts of dodecanol, 0.5 parts of diethylene glycol monobutyl ether, 10 parts of propylene glycol, 4.5 parts of potassium bicarbonate, 0.5 parts of foaming promoting stabilizer A, and 0.5 parts of triethanolamine;

[0054] Component B is a 7.5wt% aqueous solution of hydrogen peroxide;

[0055] Component C is glycerol diacetate.

[0056] The preparation method of the multifunctional broad-spectrum strong cleaning and disinfection agent in this embodiment comprises the following steps:

[0057] S1. Benzalkonium chloride, polyethylene glycol, dodecanol, diethylene glycol monobutyl ether, propylene glycol, potassium bicarbonate, foaming stabilizer A and triethanolamine were mixed and stirred for 30 minutes. Potassium hydroxide was added while stirring to adjust the pH to 10 to obtain component A for standby use.

[0058] S2. Mix component A, component B and component C in sequence and stir for 1 hour to obtain a multifunctional, broad-spectrum and powerful disinfectant.

[0059] Example 3

[0060] A multifunctional broad-spectrum strong cleaning agent, which comprises 50wt% of component A, 47wt% of component B and 3wt% of component C based on 100wt%;

[0061] Component A includes the following raw materials by weight: 0.7 parts of benzalkonium chloride, 3 parts of polyethylene glycol, 0.6 parts of dodecanol, 1 part of diethylene glycol monobutyl ether, 15 parts of propylene glycol, 5 parts of potassium bicarbonate, 1.3 parts of foaming promoter stabilizer A, and 2 parts of dicyclohexylamine nitrite;

[0062] Component B is 8.5wt% hydrogen peroxide aqueous solution;

[0063] Component C is glycerol diacetate.

[0064] The preparation method of the multifunctional broad-spectrum strong cleaning and disinfection agent in this embodiment comprises the following steps:

[0065] S1. Benzalkonium chloride, polyethylene glycol, dodecanol, diethylene glycol monobutyl ether, propylene glycol, potassium bicarbonate, foaming stabilizer A and dicyclohexylamine nitrite were mixed and stirred for 30 minutes. Potassium hydroxide was added while stirring to adjust the pH to 10.5 to obtain component A for standby use.

[0066] S2. Mix component A, component B and component C in sequence and stir for 1 hour to obtain a multifunctional, broad-spectrum and powerful disinfectant.

[0067] Example 4

[0068] This embodiment provides a multifunctional, broad-spectrum, and powerful disinfectant and a preparation method thereof. The specific implementation method is the same as that of Example 1, except that the foaming promoting stabilizer B replaces the foaming promoting stabilizer A in equal amounts.

[0069] Example 5

[0070] This embodiment provides a multifunctional, broad-spectrum, and powerful disinfectant and a preparation method thereof. The specific implementation method is the same as that of Example 1, except that the foaming promoting stabilizer C replaces the foaming promoting stabilizer A in equal amounts.

[0071] Comparative Example 1

[0072] This comparative example provides a multifunctional, broad-spectrum, and powerful disinfectant and a preparation method thereof. The specific implementation method is the same as that of Example 1, except that the foaming promoting stabilizer A is not added.

[0073] Performance Testing

[0074] The foaming performance and foam stability of the disinfectant in the above-mentioned Examples 1-5 and Comparative Example 1 were tested, and the test results are shown in Table 1.

[0075] Prepare 100 ml of disinfectant, stir at 12000 r / s for 60 seconds, then stop and record the volume of bubbles generated V 0 It is used to measure the foaming ability of the disinfectant, and then the time t required for 50 ml of liquid to precipitate is recorded after standing still. 0 Used to measure the stability of foam, the longer the time, the better the stability.

[0076] Table 1

[0077] Group <![CDATA[V 0 (ml)]]> <![CDATA[t 0 (s)]]> Example 1 670 900 Example 2 650 870 Example 3 660 875 Example 4 620 710 Example 5 630 720 Comparative Example 1 590 520

[0078] It can be seen from the data in Table 1 that the multifunctional broad-spectrum and strong decontamination agents in Examples 1-3 of the present invention have good foaming performance and foam stability as a whole. Among them, Examples 4-5 change the ratio between stearic acid and tetraethylenepentamine and the CO 2 The amount of introduction affects the foaming performance and foam stability of the foaming promoter and stabilizer, which in turn leads to a decrease in the foaming volume and foam stability time of the disinfectant; Comparative Example 1 is a case where the foaming promoter and stabilizer A are not added. The test found that the foaming performance and foam stability of the multifunctional, broad-spectrum and powerful disinfectant showed poor results.

[0079] The chemical removal and biological disinfection functions of the disinfectants of Examples 1-3 were tested, and the test results are shown in Table 2.

[0080] (1) Chemical removal function: Test the removal rate of chemical gases by the decontamination agent for 1 hour (taking sulfur dioxide as an example). The test steps are as follows:

[0081] Sample preparation: Take 1000ml of disinfectant and put it all into the experimental chamber for experiment;

[0082] Sample preparation: 10 sheets of 1m 2 Spray the disinfectant three times on the base paper (use a small spray pump to spray it as finely as possible). After the first spray is dry, spray the second time, and after the second spray is dry, spray the third time.

[0083] Test method:

[0084] ① General conditions of the test: Two air test chambers (A is a blank chamber, B is a sample chamber) are used to test the concentration of gaseous pollutants removed by the decontamination agent. The test conditions are carried out at normal temperature and pressure.

[0085] ②Test chamber requirements: The test chamber material should be non-absorbent and chemically inert (such as stainless steel or glass). The inner surface of the test chamber should be smooth. All joints should be sealed with airtight materials (such as silicone rubber) to ensure that the air leakage rate of the test chamber is less than 0.05m 3 / h; select a suitable adjustable low-speed fan and the control switch is outside the cabin.

[0086] ③Test steps: hang the untreated base paper in the blank test chamber A, and then hang the substrate sprayed with disinfectant in the test chamber B, and close the door; release sulfur dioxide gas into the blank test chamber A and the sample test chamber B; turn on the fans of the blank test chamber A and the sample test chamber B, stir for 1 minute, and mix the air in the chamber with sulfur dioxide gas evenly, then turn off the fans at the same time, sample the air in the blank chamber, and determine the sulfur dioxide pollutant concentration in the air in the blank chamber as the initial concentration, recorded as C 0 ; After 1 hour, the concentration of air pollutants in the two cabins was sampled and analyzed, which is the concentration value of cabin A and cabin B (unit: mg / m 3 ), denoted as C A With C B .

[0087] ④ Sampling: The air outlet is connected to the inlet of the air sampler outside the cabin, and 10ml of absorption liquid is passed through at a flow rate of 1.0L / min. 20L of air is sampled respectively. After the sampling is completed, the sampling tube mouth of the experimental cabin is immediately closed with a rubber cap, and the temperature during sampling is recorded. After sampling, the samples are analyzed within 6 hours.

[0088] ⑤ Calculate the removal rate according to the formula: Removal rate (%) = (C A -C B ) / C A ×100.

[0089] (2) Biological disinfection function: A disinfectant was used to carry out a disinfection test of pathogenic organisms (taking Escherichia coli as an example) to test the antibacterial rate of the disinfectant. A loop of the Escherichia coli slant culture was inoculated into a broth culture medium. After culturing at 37°C for 24 hours, 0.2 ml was taken and inoculated into three plate culture media. An equal amount of 1 ml of the disinfectant prepared in the above embodiment was taken and dropped into the three plate culture media respectively. The antibacterial rate was tested after 10 minutes of action. The rest of the operations were in compliance with the Technical Specifications for Disinfection.

[0090] Table 2

[0091]

[0092]

[0093] It can be seen from the data in Table 2 that the multifunctional broad-spectrum and strong disinfectant in Examples 1-3 of the present invention has good chemical removal and biological disinfection as a whole, that is, it has both biological and chemical disinfection functions.

[0094] The above implementation modes are only for illustrating the technical concept and features of the present invention, and their purpose is to enable people familiar with this technology to understand the content of the present invention and implement it, and they cannot be used to limit the protection scope of the present invention. Any equivalent changes or modifications made according to the spirit of the present invention should be included in the protection scope of the present invention.

Claims

1. A multifunctional broad-spectrum and powerful disinfectant, characterized in that: The decontamination agent comprises component A, component B and component C; The A component includes the following raw materials by weight: 0.3-0.7 parts of benzalkonium chloride, 1-3 parts of polyethylene glycol, 0.2-0.6 parts of fatty alcohol, 0.5-1 parts of diethylene glycol monobutyl ether, 10-15 parts of solvent, 4.5-5 parts of potassium bicarbonate, 0.5-1.3 parts of foaming promoter stabilizer, 0.5-2 parts of anticorrosive agent; The component B is an aqueous solution of hydrogen peroxide; The C component is glyceryl diacetate.

2. The multifunctional broad-spectrum strong cleaning agent according to claim 1, characterized in that: The concentration of the aqueous hydrogen peroxide solution in part B is 7.5-8.5 wt %.

3. The multifunctional broad-spectrum strong cleaning agent according to claim 2, characterized in that: Based on 100wt%, the cleaning agent includes component A of 47-51wt%, component B of 47-51wt%, and component C of 1-3wt%.

4. The multifunctional broad-spectrum strong cleaning agent according to claim 1, characterized in that: The fatty alcohol is lauryl alcohol.

5. The multifunctional broad-spectrum strong cleaning agent according to claim 1, characterized in that: The solvent is propylene glycol.

6. The multifunctional broad-spectrum strong cleaning agent according to claim 1, characterized in that: The preparation method of the foaming promoting stabilizer comprises the following steps: (1) Stearic acid and xylene are mixed, heated, stirred, tetraethylenepentamine is added, the temperature is raised to 135-155° C., refluxed for 4-6 hours, and distilled under reduced pressure to obtain a solid for use; (2) Add the solid obtained in step (1) into a mixed solvent, stir, introduce CO2, and stir to obtain a foaming promoting stabilizer.

7. The multifunctional broad-spectrum strong cleaning agent according to claim 6, characterized in that: In the step (1), the mass ratio of stearic acid to tetraethylenepentamine is 1:(0.5-0.9).

8. The multifunctional broad-spectrum strong cleaning agent according to claim 6, characterized in that: The ratio of stearic acid to CO2 is 1g:(0.7-1)L.

9. The multifunctional broad-spectrum strong cleaning agent according to claim 1, characterized in that: The anticorrosive agent is at least one of N,N-dimethylethanolamine, triethanolamine and dicyclohexylamine nitrite.

10. A method for preparing the multifunctional broad-spectrum strong cleaning agent according to any one of claims 1 to 9, characterized in that: The following steps are involved: S1, benzalkonium chloride, polyethylene glycol, fatty alcohol, diethylene glycol monobutyl ether, solvent, potassium bicarbonate, foaming promoter stabilizer and anticorrosive agent are mixed, stirred, and pH is adjusted to 10-10.5 while stirring to obtain component A for standby use; S2. Component A, component B and component C are sequentially mixed and stirred to obtain a multifunctional broad-spectrum and powerful disinfectant.

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