Multifunctional broad-spectrum strong decontamination agent and preparation method thereof

Abstract

The present application relates to the field of decontaminating agent, provide a kind of multifunctional broad-spectrum strong decontaminating agent and its preparation method, the decontaminating agent includes A component, B component, C component;By weight fraction, the A component includes the following raw materials: benzalkonium chloride 0.3-0.7 parts, polyethylene glycol 1-3 parts, fatty alcohol 0.2-0.6 parts, diethylene glycol monobutyl ether 0.5-1 part, solvent 10-15 parts, potassium bicarbonate 4.5-5 parts, foaming promoting stabilizer 0.5-1.3 parts, corrosion inhibitor 0.5-2 parts;The B component is hydrogen peroxide aqueous solution;The C component is glycerol diacetate.The decontaminating agent provided by the present application has the characteristics of good foaming performance and foam stability with chemical removal, biological disinfection function.

Description

Technical Field

[0001] The present invention relates to the field of cleaning agents, in particular to a multifunctional, broad-spectrum and powerful cleaning agent and a preparation method thereof. Background Art

[0002] Decontamination agents, also known as disinfectants, are mainly used to eliminate toxic and harmful hazardous chemicals through physical, chemical and biological effects. They can be used to remove toxic agents, radioactive substances and biological warfare agents from the surfaces of personnel, equipment, ground and buildings.

[0003] In addition to their basic functions as disinfectants, biochemical disinfectants also combine chemical elimination and biological disinfection. They can quickly and efficiently remove common industrial pollutants and toxic and hazardous chemicals, preventing the spread of hazards and restoring environmental safety. Therefore, developing disinfectants that are both highly effective in disinfecting pathogens and removing toxic chemicals is crucial. However, despite these numerous advantages, biochemical disinfectants often exist in the form of foam, which often suffers from poor foaming properties and insufficient foam stability.

[0004] Patent CN 106345097A discloses a foam disinfectant and its preparation method. The foam disinfectant includes a cationic additive, an alcohol mixture, a water-soluble polymer, a cationic surfactant, a foam stabilizer, and a corrosion stabilizer. The foam disinfectant prepared in this application can be used in a foamy state to eliminate biochemical contamination, neutralize chemical warfare agents with foam, and kill pathogenic microorganisms used as biological warfare agents. It has the advantages of high efficiency, rapidity, and low corrosion. However, the foam stabilizers used in this application are dodecyl alcohol and diethylene glycol monobutyl ether. The dodecyl alcohol is the main foam stabilizer, but the foam of dodecyl alcohol is prone to bursting after long-term use, and its foam stabilization effect still needs to be improved.

[0005] Therefore, there is an urgent need on the market for a multifunctional, broad-spectrum, and powerful disinfectant that has both chemical removal and biological disinfection functions and has good foaming performance and foam stability. Summary of the Invention

[0006] In response to the problems existing in the prior art, the present invention synthesizes a multifunctional, broad-spectrum and powerful disinfectant with three parts: component A, component B and component C, and adds a foaming promoting stabilizer to component A, which has both chemical removal and biological disinfection functions while also having good foaming performance and foam stability.

[0007] In order to achieve the above object, the technical solution adopted by the present invention is as follows:

[0008] In one aspect, the present invention provides a multifunctional, broad-spectrum, and powerful disinfectant, comprising component A, component B, and component C;

[0009] Calculated by weight, the component A comprises the following raw materials: 0.3-0.7 parts of benzalkonium chloride, 1-3 parts of polyethylene glycol, 0.2-0.6 parts of fatty alcohol, 0.5-1 parts of diethylene glycol monobutyl ether, 10-15 parts of solvent, 4.5-5 parts of potassium bicarbonate, 0.5-1.3 parts of foaming promoter stabilizer, and 0.5-2 parts of anticorrosive agent;

[0010] The component B is an aqueous solution of hydrogen peroxide;

[0011] The C component is glycerol diacetate.

[0012] In some embodiments of the present invention, the concentration of the aqueous hydrogen peroxide solution in Part B is 7.5-8.5 wt %.

[0013] Preferably, the concentration of the aqueous hydrogen peroxide solution in part B is 7.9 wt%.

[0014] In some embodiments of the present invention, based on 100 wt%, the decontamination agent includes 47-51 wt% of component A, 47-51 wt% of component B, and 1-3 wt% of component C.

[0015] The applicant uses part A composed of a surfactant as the main component, part B composed of a hydrogen peroxide aqueous solution, and diacetin, an alcohol auxiliary component C that catalyzes and promotes the combination of parts A and B, to form a multifunctional, broad-spectrum and powerful disinfection auxiliary. The A, B, and C components are mixed and stirred in sequence for use. It has the characteristics of both biological and chemical broad-spectrum disinfection, and can effectively disinfect pathogens such as spores, and can also effectively remove chemical toxic substances. It can also quickly and efficiently remove common industrial pollutants and toxic and harmful chemicals, block the spread of hazards, and restore environmental safety.

[0016] In some embodiments of the present invention, the fatty alcohol is lauryl alcohol.

[0017] In some embodiments of the present invention, the solvent is propylene glycol.

[0018] In some embodiments of the present invention, the method for preparing the foaming promoting stabilizer comprises the following steps:

[0019] (1) Stearic acid and xylene are mixed, heated, stirred, tetraethylenepentamine is added, the temperature is raised to 135-155°C, refluxed for 4-6 hours, and distilled under reduced pressure to obtain a solid for use;

[0020] (2) Add the solid obtained in step (1) to a mixed solvent, stir, introduce CO2, and stir to obtain a foaming promoting stabilizer.

[0021] In some embodiments of the present invention, in step (1), the mass ratio of stearic acid to tetraethylenepentamine is 1:(0.5-0.9).

[0022] In some embodiments of the present invention, the ratio of stearic acid to CO2 is 1g:(0.7-1)L.

[0023] The disinfectant disclosed in this application has the characteristics of both biological and chemical broad-spectrum disinfection. Currently, the products on the market can hardly have both of the above two effects. The ingredients such as benzalkonium chloride, polyethylene glycol, fatty alcohol and solvent in component A can make the disinfectant have certain foaming performance and foam stability, but the foaming performance and foam stability can not last long and still need to be improved.

[0024] The applicant uses stearic acid and tetraethylenepentamine as raw materials and then introduces an appropriate amount of carbon dioxide to synthesize a cationic surfactant as a foaming promoting stabilizer, which has the dual functions of promoting foaming and stabilizing foam. After the carboxyl group of stearic acid and the amino group of tetraethylenepentamine undergo a dehydration reaction, the foaming promoting stabilizer has a saturated alkyl long chain, imidazoline and bicarbonate structure under the action of carbon dioxide, which makes the foaming promoting stabilizer have good thermal stability, thereby slowing down the evaporation of water in the liquid film, making the formed foam less likely to burst, and improving the foam stability. In addition, this structure gives the hydrophobic carbon chains a high cohesive force and a large surface viscosity, further improving the foam stability. Furthermore, the bicarbonate structure is easily decomposed to produce carbon dioxide gas, thereby promoting foaming performance. In addition, the imidazoline structure in the foaming promoting stabilizer structure gives it a certain degree of corrosion resistance. When used in combination with the quaternary ammonium salt benzalkonium chloride, it can synergistically make the disinfectant have good corrosion resistance.

[0025] In some embodiments of the present invention, the corrosion inhibitor is at least one of N,N-dimethylethanolamine, triethanolamine, and dicyclohexylamine nitrite.

[0026] Another aspect of the present invention provides a method for preparing the multifunctional, broad-spectrum, and potent disinfectant described in the above technical solution, comprising the following steps:

[0027] S1. Benzalkonium chloride, polyethylene glycol, fatty alcohol, diethylene glycol monobutyl ether, solvent, potassium bicarbonate, foaming promoter, stabilizer and anticorrosive agent are mixed and stirred, and the pH is adjusted to 10-10.5 while stirring to obtain component A for standby use;

[0028] S2. Component A, component B and component C are sequentially mixed and stirred to obtain a multifunctional, broad-spectrum and powerful disinfectant.

[0029] Compared with the prior art, the present invention has the following beneficial effects:

[0030] (1) The present invention synthesizes a multifunctional broad-spectrum and strong disinfectant from three parts: component A, component B and component C, and adds a foaming promoting stabilizer to component A. Through the synergistic effect of the components, the multifunctional broad-spectrum and strong disinfectant has the functions of chemical removal and biological disinfection while also having good foaming performance and foam stability.

[0031] (2) The present invention uses stearic acid and tetraethylenepentamine as raw materials, and then introduces an appropriate amount of carbon dioxide to synthesize a cationic surfactant as a foaming promoter and stabilizer, which has the dual functions of promoting foaming and stabilizing foam, and can also synergistically make the disinfectant have good corrosion resistance.

[0032] (3) The disinfectant prepared by the present invention has both chemical removal and biological disinfection functions and has good foaming performance and foam stability. It can be widely used in the field of disinfectants and has good commercial application value. DETAILED DESCRIPTION

[0033] The present invention will be described below in conjunction with specific embodiments. It should be noted that the following examples are illustrative of the present invention and are intended only to illustrate the present invention and are not intended to limit the present invention. Other combinations and various modifications within the scope of the present invention may be made without departing from the spirit or scope of the present invention.

[0034] In the following examples and comparative examples, except for the foaming promoting stabilizer and the modified catalyst, the remaining compound monomers and related reagents used can be purchased from the market. Among them, polyethylene glycol is PEG 400, which was purchased from Hai'an Petrochemical Plant in Jiangsu Province; the CAS number of diacetin is 25395-31-7.

[0035] Preparation Example 1

[0036] The synthesis method of the foaming promoting stabilizer A comprises the following steps:

[0037] (1) Mix 14 g of stearic acid and 50 ml of xylene, heat to 100°C, stir for 30 min, add 9.5 g of tetraethylenepentamine, heat to 145°C, reflux for 5 h, and distill under reduced pressure to obtain a solid for later use;

[0038] (2) The solid obtained in step (1) was added to a mixed solvent (30 ml of deionized water and 50 ml of ether), stirred for 1 h, introduced CO2 at 0.1 L / min for 2 h, and stirred for 1 h to obtain a foaming promoting stabilizer A.

[0039] Preparation Example 2

[0040] The specific implementation of the foaming promoting stabilizer B is the same as that of the foaming promoting stabilizer A, except that the mass of tetraethylenepentamine in step (1) is replaced with 6 g.

[0041] Preparation Example 3

[0042] The specific implementation method of foaming promoting stabilizer C is the same as that of foaming promoting stabilizer A, except that the CO2 introduction time in step (2) is replaced with 1.5h.

[0043] Example 1

[0044] A multifunctional, broad-spectrum, and powerful disinfectant, comprising, based on 100 wt%, 49 wt% of component A, 49 wt% of component B, and 2 wt% of component C;

[0045] Component A includes the following raw materials by weight: 0.5 parts of benzalkonium chloride, 2 parts of polyethylene glycol, 0.4 parts of dodecyl alcohol, 0.8 parts of diethylene glycol monobutyl ether, 12.5 parts of propylene glycol, 4.7 parts of potassium bicarbonate, 0.9 parts of foaming promoter stabilizer A, and 1.2 parts of N,N-dimethylethanolamine;

[0046] Component B is a 7.9wt% aqueous solution of hydrogen peroxide;

[0047] Component C is glycerol diacetate.

[0048] The preparation method of the multifunctional broad-spectrum strong cleaning and disinfecting agent in this embodiment comprises the following steps:

[0049] S1. Benzalkonium chloride, polyethylene glycol, lauryl alcohol, diethylene glycol monobutyl ether, propylene glycol, potassium bicarbonate, foaming stabilizer A and N,N-dimethylethanolamine were mixed and stirred for 30 minutes. Potassium hydroxide was added while stirring to adjust the pH to 10.2 to obtain component A for use.

[0050] S2. Mix component A, component B and component C in sequence and stir for 1 hour to obtain a multifunctional, broad-spectrum and powerful disinfectant.

[0051] Example 2

[0052] A multifunctional, broad-spectrum, and powerful disinfectant, comprising, based on 100 wt%, 47 wt% of component A, 51 wt% of component B, and 2 wt% of component C;

[0053] Component A includes the following raw materials by weight: 0.3 parts of benzalkonium chloride, 1 part of polyethylene glycol, 0.2 parts of dodecyl alcohol, 0.5 parts of diethylene glycol monobutyl ether, 10 parts of propylene glycol, 4.5 parts of potassium bicarbonate, 0.5 parts of foaming promoter stabilizer A, and 0.5 parts of triethanolamine;

[0054] Component B is a 7.5wt% aqueous solution of hydrogen peroxide;

[0055] Component C is glycerol diacetate.

[0056] The preparation method of the multifunctional broad-spectrum strong cleaning and disinfecting agent in this embodiment comprises the following steps:

[0057] S1. Benzalkonium chloride, polyethylene glycol, lauryl alcohol, diethylene glycol monobutyl ether, propylene glycol, potassium bicarbonate, foaming stabilizer A and triethanolamine were mixed and stirred for 30 minutes. Potassium hydroxide was added while stirring to adjust the pH to 10 to obtain component A for standby use.

[0058] S2. Mix component A, component B and component C in sequence and stir for 1 hour to obtain a multifunctional, broad-spectrum and powerful disinfectant.

[0059] Example 3

[0060] A multifunctional, broad-spectrum, and powerful disinfectant, comprising, based on 100 wt%, 50 wt% of component A, 47 wt% of component B, and 3 wt% of component C;

[0061] Component A includes the following raw materials by weight: 0.7 parts of benzalkonium chloride, 3 parts of polyethylene glycol, 0.6 parts of dodecyl alcohol, 1 part of diethylene glycol monobutyl ether, 15 parts of propylene glycol, 5 parts of potassium bicarbonate, 1.3 parts of foaming promoter stabilizer A, and 2 parts of dicyclohexylamine nitrite;

[0062] Component B is 8.5wt% hydrogen peroxide solution;

[0063] Component C is glycerol diacetate.

[0064] The preparation method of the multifunctional broad-spectrum strong cleaning and disinfecting agent in this embodiment comprises the following steps:

[0065] S1. Benzalkonium chloride, polyethylene glycol, lauryl alcohol, diethylene glycol monobutyl ether, propylene glycol, potassium bicarbonate, foaming promoter A and dicyclohexylamine nitrite were mixed and stirred for 30 minutes. Potassium hydroxide was added while stirring to adjust the pH to 10.5 to obtain component A for standby use.

[0066] S2. Mix component A, component B and component C in sequence and stir for 1 hour to obtain a multifunctional, broad-spectrum and powerful disinfectant.

[0067] Example 4

[0068] This embodiment provides a multifunctional, broad-spectrum, and powerful disinfectant and a preparation method thereof. The specific implementation method is the same as that of Example 1, except that the foaming promoting stabilizer B replaces the foaming promoting stabilizer A in equal amounts.

[0069] Example 5

[0070] This embodiment provides a multifunctional, broad-spectrum, and powerful disinfectant and a preparation method thereof. The specific implementation method is the same as that of Example 1, except that the foaming promoting stabilizer C is used to replace the foaming promoting stabilizer A in equal amounts.

[0071] Comparative Example 1

[0072] This comparative example provides a multifunctional, broad-spectrum, and powerful disinfectant and a preparation method thereof. The specific implementation method is the same as that of Example 1, except that the foaming promoting stabilizer A is not added.

[0073] Performance Testing

[0074] The foaming performance and foam stability of the disinfectant agents of Examples 1-5 and Comparative Example 1 were tested, and the test results are shown in Table 1.

[0075] Prepare 100 ml of disinfectant and stir at 12,000 r / s for 60 seconds, then stop and record the volume of bubbles V0 to measure the foaming ability of the disinfectant. Then let it stand and observe and record the time t0 required for 50 ml of liquid to precipitate to measure the stability of the foam. The longer the time, the better the stability.

[0076] Table 1

[0077] Group <![CDATA[V0(ml)]]> <![CDATA[t0(s)]]> Example 1 670 900 Example 2 650 870 Example 3 660 875 Example 4 620 710 Example 5 630 720 Comparative Example 1 590 520

[0078] It can be seen from the data in Table 1 that the multifunctional broad-spectrum and powerful disinfectant in Examples 1-3 of the present invention have good foaming performance and foam stability as a whole. Among them, Examples 4-5 changed the ratio between stearic acid and tetraethylenepentamine and the amount of CO2 introduced during the synthesis of the foaming promoting stabilizer, which affected the foaming performance and foam stability of the foaming promoting stabilizer, thereby resulting in a decrease in the foaming volume and foam stability time of the disinfectant; Comparative Example 1 is a case where no foaming promoting stabilizer A is added. Testing found that the foaming performance and foam stability of the multifunctional broad-spectrum and powerful disinfectant showed poor results.

[0079] The chemical removal and biological disinfection functions of the disinfectants of Examples 1-3 were tested, and the test results are shown in Table 2.

[0080] (1) Chemical removal function: Test the removal rate of chemical gases by the decontamination agent in 1 hour (taking sulfur dioxide as an example). The test steps are as follows:

[0081] Sample preparation: Take 1000ml of disinfectant and put it all into the experimental chamber for experiment;

[0082] Sample preparation: 10 sheets of 1m 2Spray the disinfectant three times on the base paper (use a small spray pump to spray as finely as possible). Let the first spray dry before spraying the second time, and let the second spray dry before spraying the third time.

[0083] Test method:

[0084] ① General test conditions: Two air test chambers (A is a blank chamber, B is a sample chamber) are used to test the concentration of gaseous pollutants removed by the decontamination agent. The test conditions are carried out at normal temperature and pressure.

[0085] ②Test chamber requirements: The test chamber material should be non-absorbent and chemically inert (such as stainless steel or glass). The inner surface of the test chamber should be smooth. All joints should be sealed with airtight materials (such as silicone rubber) to ensure that the air leakage rate of the test chamber is less than 0.05m 3 / h; select a suitable adjustable low-speed fan, and the control switch is outside the cabin.

[0086] ③ Test steps: hang the untreated base paper in the blank test chamber A, and then hang the substrate sprayed with the disinfectant in the test chamber B, and close the doors; release sulfur dioxide gas into the blank test chamber A and the sample test chamber B; turn on the fans of the blank test chamber A and the sample test chamber B, stir for 1 minute, and mix the air in the chamber with sulfur dioxide gas. Then turn off the fans at the same time, sample the air in the blank chamber, and measure the sulfur dioxide pollutant concentration in the air in the blank chamber as the initial concentration, recorded as C0; after 1 hour, sample the concentration of air pollutants in the two chambers, analyze and test, which is the concentration value of chambers A and B (unit: mg / m 3 ), denoted as C A with C B .

[0087] ④ Sampling: The air outlet is connected to the inlet of the air sampler outside the cabin, and 10 ml of absorption liquid is passed through at a flow rate of 1.0 L / min to sample 20 L of air respectively. After sampling, the sampling tube mouth of the experimental cabin is immediately sealed with a rubber cap, and the temperature during sampling is recorded. The samples are analyzed within 6 hours after sampling.

[0088] ⑤ Calculate the removal rate according to the formula: Removal rate (%) = (C A -C B ) / C A ×100.

[0089] (2) Biological disinfection function: A disinfectant was used to conduct a pathogenic organism disinfection test (taking Escherichia coli as an example) to test the antibacterial rate of the disinfectant. A loop of the Escherichia coli slant culture was inoculated into a broth culture medium. After culturing at 37°C for 24 hours, 0.2 ml was taken from each of the three culture mediums. An equal amount of 1 ml of the disinfectant prepared in the above embodiment was dropped into each of the three culture mediums. The antibacterial rate was detected after 10 minutes of action. The remaining operations were in compliance with the "Technical Specifications for Disinfection".

[0090] Table 2

[0091]

[0092]

[0093] It can be seen from the data in Table 2 that the multifunctional, broad-spectrum, and powerful disinfectant in Examples 1-3 of the present invention has good chemical removal and biological disinfection functions as a whole, that is, it has both biological and chemical disinfection functions.

[0094] The above embodiments are only for illustrating the technical concept and features of the present invention. Its purpose is to enable people familiar with this technology to understand the content of the present invention and implement it. It cannot be used to limit the scope of protection of the present invention. Any equivalent changes or modifications made according to the spirit of the present invention should be included in the scope of protection of the present invention.

Claims

1. A multifunctional, broad-spectrum, and powerful disinfectant, characterized in that: The decontamination agent includes component A, component B, and component C; Calculated by weight, the A component includes the following raw materials: 0.3-0.7 parts of benzalkonium chloride, 1-3 parts of polyethylene glycol, 0.2-0.6 parts of fatty alcohol, 0.5-1 parts of diethylene glycol monobutyl ether, 10-15 parts of solvent, 4.5-5 parts of potassium bicarbonate, 0.5-1.3 parts of foaming promoter and stabilizer, 0.5-2 parts of anti-corrosion agent; The component B is an aqueous solution of hydrogen peroxide; The C component is glycerol diacetate; The concentration of the aqueous hydrogen peroxide solution of component B is 7.5-8.5 wt%; Based on 100 wt%, the decontamination agent comprises 47-51 wt% of component A, 47-51 wt% of component B, and 1-3 wt% of component C; The preparation method of the foaming promoting stabilizer comprises the following steps: (1) Stearic acid and xylene are mixed, heated, stirred, tetraethylenepentamine is added, the temperature is raised to 135-155°C, refluxed for 4-6 hours, and distilled under reduced pressure to obtain a solid for use; (2) Add the solid obtained in step (1) to a mixed solvent, stir, introduce CO2, and stir to obtain a foaming promoting stabilizer.

2. The multifunctional, broad-spectrum, and powerful disinfectant according to claim 1, characterized in that: The fatty alcohol is lauryl alcohol.

3. The multifunctional, broad-spectrum, and powerful disinfectant according to claim 1, characterized in that: The solvent is propylene glycol.

4. The multifunctional, broad-spectrum, and powerful disinfectant according to claim 1, characterized in that: In step (1) of the method for preparing the foaming promoting stabilizer, the mass ratio of stearic acid to tetraethylenepentamine is 1:(0.5-0.9).

5. The multifunctional, broad-spectrum, and powerful disinfectant according to claim 1, characterized in that: In the preparation method of the foaming promoting stabilizer, the ratio of stearic acid to CO2 is 1g:(0.7-1)L.

6. The multifunctional, broad-spectrum, and powerful disinfectant according to claim 1, characterized in that: The anti-corrosion agent is at least one of N,N-dimethylethanolamine, triethanolamine and dicyclohexylamine nitrite.

7. A method for preparing the multifunctional, broad-spectrum, and powerful disinfectant according to any one of claims 1 to 6, characterized in that: The following steps are involved: S1. Benzalkonium chloride, polyethylene glycol, fatty alcohol, diethylene glycol monobutyl ether, solvent, potassium bicarbonate, foaming promoter, stabilizer and anticorrosive agent are mixed and stirred, and the pH is adjusted to 10-10.5 while stirring to obtain component A for standby use; S2. Component A, component B and component C are sequentially mixed and stirred to obtain a multifunctional, broad-spectrum and powerful disinfectant.

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