Low-temperature probe and magnetic resonance imaging system

Abstract

The invention relates to a low-temperature probe and a magnetic resonance imaging system. The low-temperature probe comprises a shell; the at least one coil is arranged in the shell; the cooling assembly comprises a low-temperature platform capable of generating cooling capacity and a cold conducting plate capable of exchanging heat with the low-temperature platform, the cold conducting plate is arranged in the shell and provided with a coil groove, and at least part of the coil is contained in the coil groove; the coil groove is formed in the surface of the cold conduction plate, and the coil is at least partially embedded into the coil groove, so that compared with the scheme that a conventional low-temperature radio frequency coil is directly pressed to be of a cold conduction structure, the contact area between the coil and the cold conduction plate is larger, and the heat exchange capacity between the cold conduction plate and the coil can be effectively improved; therefore, refrigeration of the coil is efficiently completed, thermal noise of the coil is reduced, and the signal-to-noise ratio of the coil is increased.

Description

Technical Field

[0001] The present invention relates to the technical field related to magnetic resonance imaging systems for animals, and in particular to a low-temperature probe and a magnetic resonance imaging system. Background Art

[0002] The radio frequency coil is used to transmit radio frequency pulses and / or receive MR signals. As the front end of the signal receiving chain, it plays a vital role in imaging quality and is the core component of the magnetic resonance (nuclear magnetic resonance) imaging system.

[0003] Compared with common room temperature RF coils, cryogenic RF coils have a higher signal-to-noise ratio (SNR), higher sensitivity, faster detection speed, and higher corresponding imaging quality. The key to achieving cryogenic RF coils is how to efficiently cool the RF coil in the cryogenic probe.

[0004] The low-temperature RF coil refrigeration structure in the existing technology is complex or has too high requirements on the manufacturing process, and cannot be actually applied in the industry. There is also existing technology that presses the soft board onto the cooling structure through structural parts, but such solutions will result in poor cooling effect between the cooling structure and the coil, thereby causing a decrease in the signal-to-noise ratio and failing to meet the use requirements. Summary of the invention

[0005] Based on this, it is necessary to provide a low-temperature probe that can be actually applied in industry and has good cooling effect and good imaging quality.

[0006] The present application first provides a low-temperature probe, characterized in that it includes a shell; at least one coil, the coil is arranged in the shell; a cooling component, the cooling component includes a low-temperature platform capable of generating cold and a cold plate capable of exchanging heat with the low-temperature platform, the cold plate is arranged in the shell and a coil slot is opened on the cold plate, and the coil is at least partially accommodated in the coil slot.

[0007] In one of the embodiments, the coil groove is opened on a side surface of the cold plate close to the target to be measured; the coil includes a coil conductor and a radio frequency device, the coil conductor is at least partially accommodated in the coil groove, and there is a gap between the cold plate and the inner wall of the shell, and between the coil conductor and the inner wall of the shell.

[0008] In one of the embodiments, a surface of the cooling plate on one side close to the target to be measured is an arc surface, and the coil conductor is at least partially accommodated in the coil slot along the radial direction of the arc surface.

[0009] In one embodiment, the coil conductor at least partially protrudes from the arc surface along the radial direction of the arc surface.

[0010] In one embodiment, the cross section of the coil conductor is circular, and the depth of the coil slot is less than or equal to the dimension of the coil conductor along the depth direction of the coil slot.

[0011] In one of the embodiments, the interior of the shell is a vacuum environment, and the gap between the cooling plate and the inner wall of the shell on the side close to the target to be measured is less than or equal to 1 mm.

[0012] In one of the embodiments, the cooling plate is further provided with a through hole communicating with the coil slot, and the coil conductor and the radio frequency device are electrically connected via a conductive medium disposed in the through hole.

[0013] In one embodiment, the cryogenic probe comprises at least two coils, two adjacent coil conductors partially overlap, and one of the coil conductors at the overlapping position avoids the other coil conductor to a side away from the target to be measured.

[0014] In one of the embodiments, the coil slot is filled with cooling grease and / or cooling glue, and the cooling grease and / or cooling glue are in contact with the coil and the inner wall of the coil slot.

[0015] In one of the embodiments, the coil slot is filled with the cooling glue, and the cooling glue is arranged at intervals along the extension direction of the coil.

[0016] A second aspect of the present application provides a magnetic resonance imaging system, comprising the above-mentioned cryogenic probe and a magnetic resonance device, wherein the magnetic resonance device comprises a magnet having a scanning cavity, and the cryogenic probe can enter the scanning cavity.

[0017] The above-mentioned low-temperature probe opens a coil groove on the surface of the cold-conducting plate and embeds the coil at least partially into the coil groove. Compared with the conventional low-temperature RF coil direct pressing and cooling structure, the contact area between the coil and the cold-conducting plate in the present application is larger, which can effectively improve the heat exchange capacity between the cold-conducting plate and the coil, thereby efficiently completing the cooling of the coil, reducing the thermal noise of the coil itself, and improving the signal-to-noise ratio of the coil. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the cross-sectional structure of the cryogenic probe of this application;

[0019] Figure 2 for Figure 1 Schematic diagram of the three-dimensional structure of the middle coil;

[0020] Figure 3 for Figure 1 Schematic diagram of the cross-sectional structure of the middle cooling plate and the coil;

[0021] Figure 4 for Figure 1 Schematic diagram of the central cooling plate and coil when viewed from above;

[0022] Figure 5 for Figure 1 Schematic diagram of the cross-sectional structure of the middle cooling plate.

[0023] Figure numerals: 10, housing; 20, coil; 21, coil conductor; 22, radio frequency device; 30, cooling plate; 31, coil slot; 32, through hole; 33, card slot. DETAILED DESCRIPTION

[0024] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific embodiments disclosed below.

[0025] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0026] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of the present invention, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0027] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0028] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0029] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. The terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used herein are for illustrative purposes only and are not intended to be the only implementation method.

[0030] Please combine Figure 1-Figure 4 As shown, the present application first provides a low-temperature probe, including a shell 10; at least one coil 20, the coil 20 is arranged in the shell 10; a cooling component, the cooling component includes a low-temperature platform (not shown in the figure) capable of generating cold and a cold plate 30 capable of exchanging heat with the low-temperature platform, the cold plate 30 is arranged in the shell 10 and a coil slot 31 is opened on the cold plate 30, and the coil 20 is at least partially accommodated in the coil slot 31.

[0031] For the convenience of description, the coil 20 herein refers to a radio frequency coil, which is used to transmit radio frequency pulses and / or receive MR signals.

[0032] The low-temperature platform can generate cold and transfer the cold to the cold plate 30 through heat exchange to ensure that the cold plate 30 is in an ultra-low temperature state. The temperature of the cold plate 30 is as low as 30K or lower, so that the cold plate 30 is used as a relay to achieve heat exchange through the contact between the cold plate 30 and the coil 20, thereby cooling the coil 20, thereby reducing the thermal noise of the coil 20 itself, improving the sensitivity of the coil 20, and improving the imaging quality.

[0033] Specifically, the heat exchange between the low-temperature platform and the cold plate 30 can be achieved through common heat exchange forms, such as contact or cooling circulation pipelines. As long as the cold energy generated by the low-temperature platform can cool the cold plate 30 to an ultra-low temperature state, the present application will not make further limitations here.

[0034] In the present application, by opening a coil slot 31 on the surface of the cold plate 30 and embedding the coil 20 at least partially into the coil slot 31, compared with the conventional low-temperature RF coil direct pressing and cooling structure solution, the contact area between the coil 20 and the cold plate 30 in the present application is larger, which can effectively improve the heat exchange capacity between the cold plate 30 and the coil 20, thereby efficiently completing the cooling of the coil 20, reducing the thermal noise of the coil 20 itself, and improving the signal-to-noise ratio of the coil 20.

[0035] In addition, the present application can isolate the low-temperature part from the target to be measured through the shell 10 by arranging the cold plate 30 and the coil 20 inside the shell 10, so that the temperature of the shell 10 is close to normal temperature, reducing the possibility of frostbite of the target to be measured. In some embodiments, the shell 10 can be made of a ceramic material containing aluminum nitride, and in particular, it can be made of an AlN (aluminum nitride) composite ceramic material with BN (boron nitride). These materials can be made into any shape, including hollow and concave. In this embodiment, the shell 10 is a hollow shell.

[0036] In some embodiments, the housing 10 further has an insulating portion, which is integrally formed; the insulating portion can reduce the amount of cold transferred from the inside of the housing 10 to the outer surface of the housing 10, further reducing the possibility of frostbite on the target to be measured. Figure 2-Figure 4 As shown, in some embodiments, the coil slot 31 is opened on the surface of one side of the cold plate 30 close to the target to be measured; the coil 20 includes a coil conductor 21 and a radio frequency device 22; wherein the radio frequency device 22 is used to realize radio frequency pulse transmission and / or MR signal reception, the coil conductor 21 is at least partially accommodated in the coil slot 31, and there is a gap between the coil conductor 21 and the inner wall of the shell 10 close to the target to be measured.

[0037] It can be understood that the smaller the distance between the coil conductor 21 and the target to be measured, the better the signal-to-noise ratio of the coil 20. The coil slot 31 is opened on the side surface of the cold plate 30 close to the target to be measured, which can ensure that the distance between the coil conductor 21 and the target to be measured is relatively small after being embedded in the coil slot 31, so as to achieve the effect of improving the coil signal-to-noise ratio.

[0038] In addition, if any one of the coil conductor 21 and the cold plate 30 is in direct contact with the shell 10, the cold on the coil conductor 21 and the cold plate 30 will be transferred to the shell 10, causing the temperature of the shell 10 to be too low, and there is a risk of frostbite on the target to be measured. By arranging the coil conductor 21 and the cold plate 30 separately from the shell 10, so that there is a gap between the two and the shell 10, the two can be prevented from contacting the shell 10, thereby effectively reducing the heat conduction efficiency between the two and the shell 10 and reducing the risk of frostbite.

[0039] In some embodiments, the surface of one side of the cold conduction plate 30 close to the target to be measured is an arc surface, and the coil conductor 21 is partially accommodated in the coil groove 31 along its own extension direction, and / or is at least partially accommodated in the coil groove 31 along the radial direction of the arc surface; of course, the coil conductor 21 can also be partially accommodated in the coil groove 31 along other directions, and the present application does not limit this one by one.

[0040] In some embodiments, the coil 20 is at least partially accommodated in the coil slot 31 along the radial direction of the arc surface, and the coil conductor 21 at least partially protrudes from the arc surface along the radial direction of the arc surface.

[0041] While accommodating the coil conductor 21 and increasing the contact area between the coil conductor 21 and the cold plate 30, the distance between the coil conductor 21 and the target to be measured is reduced, thereby further improving the coil signal-to-noise ratio; in addition, it is also possible to ensure that there is an obvious gap between the cold plate 30 and the inner wall of the shell 10 to avoid accidental contact between the cold plate 30 and the shell 10 due to shaking or other external forces, and the cold energy of the cold plate 30 is directly transferred to the shell 10.

[0042] Preferably, the area of ​​the coil conductor 21 protruding from the arc surface accounts for less than or equal to one half of its cross-sectional area.

[0043] In some embodiments, the coil conductor 21 at least partially protrudes from the arc surface along the radial direction of the arc surface, and the depth of the coil groove 31 is less than or equal to the dimension of the coil conductor 21 along the depth direction of the coil groove 31; that is, the coil conductor 21; so as to reduce the distance between the bottom wall of the coil groove 31 and the coil conductor 21, thereby increasing the cold transfer efficiency.

[0044] Preferably, the bottom wall of the coil slot 31 is in contact with the coil conductor 21 to increase the contact area between the cold conduction plate 30 and the coil conductor 21 as much as possible, thereby increasing the cold transfer efficiency.

[0045] In some embodiments, the cross section of the coil slot 31 is circular, and the coil conductor 21 is partially accommodated in the coil slot 31 along the radial direction of the arc surface and fits with the inner wall of the coil slot 31 .

[0046] Of course, the coil 20 and the cold plate 30 may also be in other shapes, such as both being rectangular, etc. As long as the coil conductor 21 can conform to the inner wall of the coil slot 31 to obtain a larger contact area, this application does not make any further restrictions. Figure 2-Figure 4 As shown, in some embodiments, the depth of the coil slot 31 is equal to the dimension of the coil conductor 21 along the depth direction of the coil slot 31 , and the coil conductor 21 is completely accommodated in the coil slot 31 .

[0047] The more the coil conductor 21 is accommodated in the coil slot 31, the stronger the heat conduction capacity between the coil conductor 21 and the coil slot 31, and the better the cooling effect on the coil 20. Therefore, by completely accommodating the coil conductor 21 in the coil slot 31, the cooling effect of the cold plate 30 on the coil 20 can be maximized, thereby reducing the thermal noise of the coil 20 itself and improving the sensitivity of the coil 20, thereby achieving the effect of increasing the detection speed and improving the imaging quality.

[0048] Please combine Figure 2-Figure 4 As shown, in some embodiments, the interior of the housing 10 is a vacuum environment, and the gap between the coil conductor 21 and the inner wall of the housing 10 is less than or equal to 1 mm.

[0049] Since heat conduction is mainly conducted through air or objects as the medium, the heat conduction between the shell 10, the cold plate 30 and the coil 20 can be blocked by evacuating the shell 10; on this basis, the position of the coil conductor 21 can be as close to the inner wall of the shell 10 as possible to minimize the distance between the coil conductor 21 and the target to be measured, and there is no need to consider whether the close distance between the coil conductor 21 and the shell 10 will cause the temperature of the shell 10 to be too low and freeze the target to be measured. The distance between the coil conductor 21 and the target to be measured can be minimized under the premise of ensuring the safety of the target to be measured, thereby achieving the effect of improving the signal-to-noise ratio of the coil 20.

[0050] In the present application, the gap between the coil conductor 21 and the inner wall of the housing 10 is designed to be less than or equal to 1 mm, so as to ensure that a small distance is maintained between the coil conductor 21 and the target to be measured, thereby obtaining a higher signal-to-noise ratio.

[0051] Through calculation, simulation and test verification, the distance between the coil conductor 21 and the inner wall of the housing 10 is controlled within the above range, and the signal-to-noise ratio of the coil 20 can meet the actual use requirements.

[0052] Furthermore, in some embodiments, the bottom wall of the coil slot 31 is also tangent to the coil conductor 21; it can be understood that the efficiency of heat exchange through contact between the coil conductor 21 and the bottom wall of the coil slot 31 is much higher than the heat conduction efficiency in the non-contact state, so such a setting can further improve the cooling effect and the signal-to-noise ratio of the coil 20.

[0053] In summary, the present application comprehensively designs multiple factors such as the groove depth of the coil groove 31, the relative position relationship between the coil conductor 21 and the cold plate 30, the internal environment of the shell 10, and the gap range between the coil conductor 21 and the shell 10, so that the low-temperature probe in the present application has excellent performance in imaging effect, cooling effect on the coil 20, and safety of use (risk of frostbite on the target to be measured).

[0054] In some embodiments, a surface of the cold conduction plate 30 close to the target to be measured is an arc surface, and the coil conductor 21 is at least partially accommodated in the coil slot 31 along the radial direction of the arc surface.

[0055] In some embodiments, the portion of the coil conductor 21 protruding from the cold plate 30 toward the side close to the target to be measured is less than or equal to half the diameter of the coil conductor 21, so as to ensure that there is a sufficiently large contact area between the coil conductor 21 and the cold plate 30, and the cold transfer capacity between the coil conductor 21 and the cold plate 30 can meet the demand, thereby achieving the effect of reducing the thermal noise of the coil 20 and improving the signal-to-noise ratio of the coil 20.

[0056] Please refer to Figure 5 As shown, in some embodiments, a through hole 32 connected to the coil slot 31 is provided on the surface of the side of the cold conduction plate 30 away from the target to be measured, and the RF device 22 passes through the through hole 32 to protrude from the side of the cold conduction plate 30 away from the target to be measured, and the coil conductor 21 and the RF device 22 are electrically connected via a conductive medium disposed in the through hole 32.

[0057] During the actual installation process, the coil conductor 21 is first installed in the coil slot 31 , and then the RF device 22 is electrically connected to the coil conductor 21 via a conductive medium, thereby completing the installation between the coil 20 and the cold conduction plate 30 .

[0058] In some embodiments, a slot 33 connected to the through hole 32 is further provided on the surface of the side of the cold plate 30 away from the target to be measured; it is understandable that in order to ensure the normal installation of the RF device 22, there must be a certain gap between the RF device 22 and the through hole 32, and the two cannot be completely close together. The slot 33 can be used to clamp and fix the RF device 22 after the coil 20 is installed to prevent the RF device 22 from moving relative to the cold plate 30. On the other hand, it can reduce the depth of the through hole 32, so that the coil conductor 21 can pass through the through hole 32 to complete the welding with the RF device 22 during the welding process, thereby reducing the difficulty of welding between the RF device 22 and the coil conductor 21.

[0059] In some embodiments, the extension direction of the coil slot 31 is consistent with the arrangement direction of the coil conductor 21, that is, the coil slot 31 is designed to conform to the coil conductor 21, thereby minimizing the gap between the coil conductor 21 and the coil slot 31 as much as possible, and increasing the cooling capacity between the cold plate 30 and the coil conductor 21. Figure 4 As shown, the extension direction of each position of the coil slot 31 is the same as the extension direction of the corresponding position of the coil conductor 21.

[0060] Please refer to Figure 2As shown, in some embodiments, the cryogenic probe includes at least two coils 20, two adjacent coil conductors 21 partially overlap, and one of the coil conductors 21 at the overlapping position avoids the other coil conductor 21 to the side away from the target to be measured.

[0061] In the case of multiple coils 20, partial overlap between adjacent coils 20 is a common arrangement method, which can improve the signal-to-noise ratio; the avoidance mentioned here refers to the overlapping portion of one of the coil conductors 21 being bent toward the side away from the target to be measured to form a bridge or other structure, while ensuring that the shape of other parts of the coil conductor 21 remains unchanged, thereby avoiding contact between two adjacent coil conductors 21 at the overlapping portion and causing mutual interference.

[0062] It is understandable that if the coil conductor 21 is evaded to the side close to the target to be measured, the distance between the evaded portion of the coil conductor 21 and the inner wall of the housing 10 may be reduced, and may even protrude from the coil slot 31, so that the cold energy is conducted to the housing 10 through the evaded portion of the coil conductor 21, which affects the cooling effect of the coil 20 and has a certain risk of freezing the target to be measured.

[0063] If the coil conductor 21 is moved as a whole away from the target to ensure that the distance between the avoided part of the coil conductor 21 and the housing 10 remains within an appropriate range, the distance between the coil conductor 21 and the target to be measured will increase, thereby reducing the signal-to-noise ratio of the coil 20.

[0064] In the present application, by moving the coil conductor 21 to the side away from the target to be measured, the distance between the coil 20 as a whole and the shell 10 will not increase, thereby not affecting the cooling effect of the coil 20 or posing a risk of frostbite; in addition, only the distance between part of the coil conductor 21 at the overlapping position and the target to be measured is increased, while the distance between most of the other coil conductors 21 and the target to be measured remains unchanged, thereby relatively reducing the impact on the overall signal-to-noise ratio of the coil 20.

[0065] Furthermore, in some embodiments, the depth of the coil groove 31 at the overlapping portion of the coil 20 is deeper than that at other positions to accommodate the avoided portion of the coil conductor 21 .

[0066] In some embodiments, the coil slot 31 is filled with cooling grease and / or cooling glue, and the cooling grease and / or cooling glue are in contact with the coil 20 and the inner wall of the coil slot 31; the cooling grease and / or cooling glue can increase the contact area between the coil 20 and the coil slot 31, thereby further improving the heat conduction capacity between the cooling plate 30 and the coil 20, and improving the cooling effect of the coil 20.

[0067] In some embodiments, the coil slot 31 is filled with cooling glue, which is arranged at intervals along the length direction of the coil 20 and can bond and fix the coil 20 and the cooling plate 30 .

[0068] It can be understood that the cooling glue can be used to fix the coil 20 to the cooling plate 30 to increase the fixing reliability between the coil 20 and the cooling plate 30, and the cooling glue is arranged at intervals along the length direction of the coil 20, which can ensure that the coil 20 is firmly fixed while minimizing the amount of cooling glue used and reducing production costs.

[0069] Preferably, along the length direction of the coil 20, the distance between two adjacent fixing points of the cooling glue is less than or equal to 5 mm.

[0070] In some embodiments, the thermal conductivity of the cooling grease and / or the cooling glue is greater than or equal to 1 w / (m·k).

[0071] It can be understood that in order to reduce the loss of cold on the cold plate 30 during the process of passing through the cooling grease and / or cooling glue, it is necessary to increase the thermal conductivity of the cooling grease and / or cooling glue as much as possible; after calculation, simulation and experimental verification, when the thermal conductivity of the cooling grease and / or cooling glue is greater than or equal to 1w / (m·k), the heat conduction efficiency and product cost can be balanced, that is, while ensuring that the coil 20 has a higher cooling efficiency, the cost of the cooling grease and / or cooling glue is relatively low.

[0072] Please combine Figure 2 as well as Figure 3 As shown, in some embodiments, the surface formed by the coil 20 is parallel to the surface of the side of the cold plate 30 close to the target to be measured; that is, the coil 20 and the surface of the side of the cold plate 30 close to the target to be measured are contoured to ensure that the coil 20 can be accommodated in the coil slot 31 and can fit tightly against the inner wall of the coil slot 31.

[0073] In addition, the cooling plate 30 and the shell 10 are usually arc-shaped. Such arrangement of the coil 20 can also help increase the coverage range of the low-temperature probe on the target to be measured, so as to facilitate magnetic resonance imaging of different parts of the target to be measured.

[0074] Of course, the coil 20, the cold plate 30 and the shell 10 can change their shapes according to actual needs. For example, the cross-sectional shape of the coil 20 is a rectangle, the cold plate 30 and the shell 10 are both rectangular cubes, etc. As long as the surface formed by the coil 20 is parallel to the surface of the cold plate 30 on one side close to the target to be measured, the present application does not make any further limitations here.

[0075] The second aspect of the present application provides a magnetic resonance imaging system, comprising a magnetic resonance device (not shown) and the above-mentioned cryogenic probe. The magnetic resonance device comprises a magnet, the magnet has a scanning cavity, and the cryogenic probe can enter the scanning cavity. The magnetic resonance imaging system can be used for animal imaging. The animal can be a mouse, such as an experimental mouse.

[0076] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0077] The above-mentioned embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. A low temperature probe, It is characterized in that include Housing (10); at least one coil (20), the coil (20) being disposed in the housing (10); A cooling component, the cooling component comprising a low-temperature platform capable of generating cold energy and a cold conduction plate (30) capable of performing heat exchange with the low-temperature platform, the cold conduction plate (30) being arranged in the shell (10) and having a coil slot (31) formed on the cold conduction plate (30), the coil (20) being at least partially accommodated in the coil slot (31).

2. The cryogenic probe according to claim 1, It is characterized in that The coil slot (31) is provided on a surface of a side of the cooling plate (30) close to the target to be measured; The coil (20) comprises a coil conductor (21) and a radio frequency device (22); the coil conductor (21) is at least partially accommodated in the coil slot (31); and there are gaps between the cold plate (30) and the inner wall of the housing (10), and between the coil conductor (21) and the inner wall of the housing (10).

3. The cryogenic probe according to claim 2, It is characterized in that The surface of one side of the cold conduction plate (30) close to the target to be measured is an arc surface, and the coil conductor (21) is at least partially accommodated in the coil slot (31) along the radial direction of the arc surface.

4. The cryogenic probe according to claim 3, It is characterized in that The coil conductor (21) at least partially protrudes from the arc surface along the radial direction of the arc surface.

5. The cryogenic probe according to claim 4, It is characterized in that The depth of the coil slot (31) is less than or equal to the dimension of the coil conductor (21) along the depth direction of the coil slot (31).

6. The cryogenic probe according to claim 3, It is characterized in that The interior of the housing (10) is a vacuum environment, and the gap between the coil conductor (21) and the inner wall of the housing (10) on a side close to the target to be measured is less than or equal to 1 mm.

7. The cryogenic probe according to claim 2, It is characterized in that The cooling plate (30) is also provided with a through hole (32) communicating with the coil slot (31); the coil conductor (21) and the radio frequency device (22) are electrically connected via a conductive medium disposed in the through hole (32).

8. The cryogenic probe according to claim 2, It is characterized in that The cryogenic probe comprises at least two coils (20), two adjacent coil conductors (21) partially overlap each other, and one of the coil conductors (21) at the overlapping position avoids the other coil conductor (21) to a side away from the target to be measured.

9. The cryogenic probe according to claim 1, It is characterized in that The coil slot (31) is filled with cooling grease and / or cooling glue, and the cooling grease and / or cooling glue are in contact with the coil (20) and the inner wall of the coil slot (31).

10. The cryogenic probe according to claim 8, It is characterized in that The coil groove (31) is filled with the cooling glue, and the cooling glue is arranged at intervals along the extension direction of the coil (20).

11. A magnetic resonance imaging system, It is characterized in that It comprises a low-temperature probe as claimed in any one of claims 1 to 10 and a magnetic resonance device, wherein the magnetic resonance device comprises a magnet having a scanning cavity, and the low-temperature probe can enter the scanning cavity.

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