Medicine formula for treating stomach illness
By using the formulas of turtle lotus, baiwei lotus, scented tangerine and rapeseed oil in gastric disease treatment drugs, the problem of the inability to completely absorb the efficacy caused by the short residence time of existing drugs is solved, and better treatment effects for gastric disease are achieved.
Patent Information
- Application Number
- CN202510351763.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-24
- Publication Date
- 2025-06-13
AI Technical Summary
The existing gastric disease treatment drugs stay in the human body for a short time, resulting in the inability to completely absorb the efficacy of the drug, causing waste.
A drug formula, including turtle lotus, turtle lotus, turtle oil, and rapeseed oil, is used to enhance the adhesion and transdermal absorption of the drug through specific ratios and preparation methods.
Prolong the adhesion time of the drug on the ulcer surface, ensure the full effect of the drug, and maximize the therapeutic effect.
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of gastric disease treatment, and particularly to a drug formula for treating gastric diseases. Background Art
[0002] Gastric diseases are highly prevalent diseases globally, and common types include gastritis, functional dyspepsia, gastric ulcer, etc. Western medicine treatment mainly uses proton pump inhibitors and gastric mucosal protectants, but long-term use may cause intestinal flora imbalance and osteoporosis. Therefore, a traditional Chinese medicine drug formula is needed for mild treatment to reduce side effects.
[0003] When treating existing gastric diseases, the residence time of the drug in the human body is relatively short, resulting in incomplete absorption of the drug effect and waste. Summary of the Invention
[0004] The purpose of the present invention is to solve the deficiencies in the prior art, and a drug formula for treating gastric diseases is proposed. The technical solution adopted by the present invention is as follows:
[0005] A drug formula for treating gastric diseases, by weight, includes the following raw materials:
[0006] 8 - 12 grams of Chelidonium majus L. var. asiaticum Regel;
[0007] 8 - 12 grams of Thalictrum elegans Wall.;
[0008] 50 - 70 grams of Aucklandia lappa Decne.;
[0009] 6 - 10 grams of rapeseed oil.
[0010] As an improvement, the preferred weights of the raw materials are:
[0011] 10 grams of Chelidonium majus L. var. asiaticum Regel;
[0012] 10 grams of Thalictrum elegans Wall.;
[0013] 60 grams of Aucklandia lappa Decne.;
[0014] 8 grams of rapeseed oil.
[0015] As an improvement, the dosage of Aucklandia lappa Decne. is 50 - 70 grams, which is used to enhance the efficacy of regulating qi and relieving pain.
[0016] As an improvement, the rapeseed oil is used as a vehicle, which is used to adjust the adhesiveness and transdermal absorbability of the drug.
[0017] As an improvement, the preparation method steps of the drug formula include:
[0018] First step, washing: Wash the Chelidonium majus L. var. asiaticum Regel, Thalictrum elegans Wall. and Aucklandia lappa Decne. bought back;
[0019] Step 2. Slicing: Slice the washed Jin Guilian, Bai Wei Lian, and Aucklandia lappa into slices with uniform thickness;
[0020] Step 3. Drying: Dry the sliced Jin Guilian, Bai Wei Lian, and Aucklandia lappa;
[0021] Step 4. Weighing: Weigh and proportion the dried Jin Guilian, Bai Wei Lian, and Aucklandia lappa according to the above weights respectively;
[0022] Step 5. Crushing: Crush the weighed Jin Guilian, Bai Wei Lian, and Aucklandia lappa into powder;
[0023] Step 6. Mixing: Mix and blend the powdered Jin Guilian, Bai Wei Lian, Aucklandia lappa, and rapeseed oil.
[0024] The beneficial effects of the present invention are as follows:
[0025] A drug formula for treating gastric diseases according to the present invention has a good therapeutic effect on gastric diseases during use. At the same time, rapeseed oil is added as an excipient in this application. Rapeseed oil can form a hydrophobic protective film, so that the drug can adhere to the ulcer surface for a longer time, thereby ensuring the full exertion of the drug effect and maximizing the drug effect. Specific embodiments
[0026] In order to make the content of the present invention easier to be clearly understood, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention.
[0027] By weight, it includes the following raw materials:
[0028] 8 - 12 grams of Jin Guilian;
[0029] 8 - 12 grams of Bai Wei Lian;
[0030] 50 - 70 grams of Aucklandia lappa;
[0031] 6 - 10 grams of rapeseed oil.
[0032] The preferred weight of the raw materials is:
[0033] 10 grams of Jin Guilian;
[0034] 10 grams of Bai Wei Lian;
[0035] 60 grams of Aucklandia lappa;
[0036] 8 grams of rapeseed oil.
[0037] The dosage of Aucklandia lappa is 50 - 70 grams, which is used to enhance the efficacy of regulating qi and relieving pain.
[0038] Rapeseed oil is used as an excipient to regulate the adhesiveness and transdermal absorbability of the drug.
[0039] The preparation method steps of the drug formula are as follows: Wash the purchased Jin Guilian, Baiwei Lian and Aucklandia lappa, then cut the washed Jin Guilian, Baiwei Lian and Aucklandia lappa into slices with uniform thickness, then dry the sliced Jin Guilian, Baiwei Lian and Aucklandia lappa, then weigh and proportion the dried Jin Guilian, Baiwei Lian and Aucklandia lappa according to the above weights, then grind the weighed Jin Guilian, Baiwei Lian and Aucklandia lappa into powder, and then mix and blend the powdered Jin Guilian, Baiwei Lian and Aucklandia lappa with rapeseed oil.
[0040] Jin Guilian:
[0041] Antibacterial and anti-inflammatory: It has a significant inhibitory effect on Helicobacter pylori;
[0042] Protect the gastric mucosa: Reduce the activity of pepsin and reduce the erosion of the ulcer surface by gastric acid;
[0043] Clear heat and relieve pain: Relieve burning pain in the stomach, and its mechanism is related to inhibiting the expression of COX-2.
[0044] Aucklandia lappa:
[0045] Regulate gastrointestinal motility: Promote gastrointestinal peristalsis by activating 5-HT4 receptors, and relieve abdominal distension and belching;
[0046] Spasmolytic and analgesic: Inhibit smooth muscle contraction;
[0047] Anti-inflammatory and immune: Reduce the levels of pro-inflammatory factors such as IL-6 and TNF-α, and reduce gastric mucosal inflammation.
[0048] Rapeseed oil
[0049] Physical protection: Form a hydrophobic film in the stomach, extend the adhesion time of the drug, and reduce gastric acid stimulation;
[0050] Solubilization and penetration promotion: Oleic acid can increase the solubility of costunolide and promote the transdermal absorption of active ingredients.
[0051] This application requires about two courses of treatment for common gastric diseases such as gastric acid and gastric distension. This application requires six to ten courses of treatment for gastric perforation and gastric bleeding. In addition to the above diseases, it can also treat various gastric diseases such as duodenum and gastric erosion.
[0052] The above are only the preferred embodiments of this invention patent, and are not intended to limit this invention patent. Any modifications, equivalent replacements, and improvements made within the spirit and principles of this invention patent shall be included within the protection scope of this invention patent.
Claims
1. A pharmaceutical formulation for treating gastric disease, characterized in that: By weight, the following APIs are included: 8-12 grams of golden beetle lotus; 8-12 grams of white lotus; 50-70 grams of costusroot; 6-10 grams of rapeseed oil.
2. A pharmaceutical formulation for treating gastric disease according to claim 1, characterized in that: The preferred weight of the bulk drug is: 10g of Golden Toad Lotus; 10g of Ligusticum chuanxiong; 60g of costusroot; 8 grams of rapeseed oil.
3. A pharmaceutical formulation for treating gastric disease according to claim 1, characterized in that: The dosage of costus root is 50-70 grams, which is used to enhance the effect of regulating qi and relieving pain.
4. A pharmaceutical formulation for treating gastric disease according to claim 1, characterized in that: The rapeseed oil is used as an excipient to adjust the adhesion and transdermal absorption of the drug.
5. The pharmaceutical formulation for treating gastric disease according to claim 1, characterized in that: The preparation method of the drug formulation comprises the following steps: Step 1: Wash: Wash the purchased golden beetle lotus, white lotus and costus root; Step 2: Slice: Cut the washed lotus root, lotus root and wood fragrance into slices of uniform thickness; Step 3: Drying: Dry the sliced golden lotus, white lotus and costus root in the sun; Step 4, weighing: weigh and mix the dried golden lotus, white lotus and costus root according to the above weights respectively; Step 5: Crush: Crush the weighed golden lotus, white lotus and costus root into powder; Step 6. Mixing: Mix the powdered Scarabaeia, Ligusticum chuanxiong, Aucklandia lappa and rapeseed oil.