Veterinary drug composition containing traditional Chinese medicine components and preparation method thereof

By selecting and mixing specific Chinese medicine raw materials and preparing veterinary drug compositions by decoction, filtration, concentration and mixing auxiliary materials, the shortcomings of existing veterinary drugs in preventing, treating and improving animal symptoms are solved, and the stability and shelf life of the composition are improved.

CN120131768APending Publication Date: 2025-06-13HENAN ANSHENG ANIMAL PHARM CO LTD
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Patent Information

Application Number
CN202410962247.5
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-07-18
Publication Date
2025-06-13

AI Technical Summary

Technical Problem

Existing veterinary drugs are difficult to effectively prevent, treat or improve the symptoms of clearing heat, detoxifying, stopping diarrhea, cooling blood and dispersing wind in animals, and there are problems of unstable state and insufficient shelf life.

Method used

A veterinary medicine composition containing Chinese medicine ingredients is adopted, and a stable veterinary medicine composition is prepared by selecting traditional Chinese medicine raw materials such as honeysuckle, forsythia, coptis chinensis, chrysanthemum, cheetah, sea jinsha, Houttuynia cordata, Bupleurum, Panax notoginseng, Panax notoginseng, Salvia miltiorrhiza, Shandou root and Banzhilou, and mixed in a specific proportion, and prepared by decoction, filtration, concentration and mixing with auxiliary materials.

Benefits of technology

The pharmacological effects of the composition are achieved, such as clearing heat and detoxifying, stopping diarrhea and dysentery, cooling blood and dispersing wind, and improving the state stability and shelf life of the composition.

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Abstract

The invention belongs to the technical field of veterinary drug compositions, and particularly relates to a veterinary drug composition containing traditional Chinese medicine ingredients, which comprises the following raw materials in variety and proportion: 8-15 parts of honeysuckle, 3-6 parts of fructus forsythiae, 6-9 parts of coptis chinensis, 12-20 parts of chrysanthemum, 6-8 parts of semen plantaginis, 7-10 parts of lygodium japonicum, 6-10 parts of houttuynia cordata, 10-13 parts of radix bupleuri, 3-7 parts of pseudo-ginseng, 6-12 parts of salvia miltiorrhiza, 6-8 parts of subprostrate sophora and 12-20 parts of sculellaria barbata. According to the veterinary medicine composition containing the traditional Chinese medicine components, by selecting honeysuckle, fructus forsythiae, coptis chinensis, chrysanthemum, semen plantaginis, lygodium japonicum, houttuynia cordata, radix bupleuri, pseudo-ginseng, salvia miltiorrhiza, subprostrate sophora and sculellaria barbata, the effects of clearing away heat and toxic materials, stopping diarrhea and dysentery, cooling blood and dispelling wind, nourishing yin and moistening dryness, strengthening the body resistance to eliminate pathogenic factors and expelling and killing insects of the composition can be guaranteed; and by arranging the stabilizer, the cosolvent and the preservative, the state stability and the service life of the composition can be guaranteed.
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Description

Technical Field

[0001] The present invention belongs to the technical field of veterinary drug compositions, and particularly relates to a veterinary drug composition containing traditional Chinese medicine components and a preparation method thereof. Background Art

[0002] Animal husbandry is a production department where people utilize the living functions of animals to obtain animal products or draft animals through breeding. Animal husbandry production is particularly important in the social environment. To ensure the healthier growth of livestock and poultry, a veterinary drug composition containing traditional Chinese medicine is needed. A veterinary drug composition containing traditional Chinese medicine components refers to a veterinary drug product made from one or more traditional Chinese medicine raw materials through scientific compatibility and processing for preventing, treating, or improving animal diseases. These traditional Chinese medicine raw materials usually come from natural plants, animals, or minerals, have unique pharmacological effects and biological activities, and have the advantages of clearing heat and detoxifying, stopping diarrhea and dysentery, cooling blood and dispelling wind, as well as good state stability and ensuring the shelf life of use. Summary of the Invention

[0003] To solve the problems raised in the above background art, the present invention provides a veterinary drug composition containing traditional Chinese medicine components and a preparation method thereof, which have the characteristics of being able to achieve the effects of clearing heat and detoxifying, stopping diarrhea and dysentery, cooling blood and dispelling wind, high state stability of the composition, and ensuring the shelf life of use.

[0004] To achieve the above object, the present invention provides the following technical solution: A veterinary drug composition containing traditional Chinese medicine components, comprising the following raw material components, the types and proportions of the raw materials are: honeysuckle 8 - 15: forsythia 3 - 6: coptis 6 - 9: chrysanthemum 12 - 20: plantain seed 6 - 8: lygodium japonicum 7 - 10: houttuynia cordata 6 - 10: bupleurum 10 - 13: notoginseng 3 - 7: salvia miltiorrhiza 6 - 12: sophora subprostrata 6 - 8: scutellaria barbata 12 - 20.

[0005] Preferably, the auxiliary materials for preparing the composition are one or more of corn starch, fish meat, lard, and soybean oil.

[0006] Preferably, the additives for preparing the composition are a stabilizer, a solubilizer, and a preservative. The stabilizer is selected as an antioxidant, the solubilizer is selected as glycerol, and the preservative is selected as sodium benzoate.

[0007] Preferably, a preparation method of a veterinary drug composition containing traditional Chinese medicine components comprises the following steps. Step 1, selection of traditional Chinese medicine: Select honeysuckle, forsythia, coptis, chrysanthemum, plantain seed, lygodium japonicum, houttuynia cordata, bupleurum, notoginseng, salvia miltiorrhiza, sophora subprostrata, and scutellaria barbata, and mix and process them according to the ratio of 8 - 15:3 - 6:6 - 9:12 - 20:6 - 8:7 - 10:6 - 10:10 - 13:3 - 7:6 - 12:6 - 8:12 - 20.

[0008] Step 2: Cleaning and soaking: After mixing traditional Chinese medicines in appropriate proportions, the mixed traditional Chinese medicines are cleaned and dried.

[0009] Step 3: Extraction of traditional Chinese medicines: Then, the traditional Chinese medicine raw materials are decocted, generally for a time controlled within 2 - 4 hours, and the decocted traditional Chinese medicines are filtered. After the filtration of the traditional Chinese medicines is completed, the medicinal residues are removed, and then the traditional Chinese medicines are concentrated with the help of equipment.

[0010] Step 4: Mixed preparation: The concentrated traditional Chinese medicine is mixed with corn starch, lard, and soybean oil, and at the same time, it is mixed with antioxidants, glycerol, and sodium benzoate. Then, it is uniformly mixed with the help of auxiliary mixing equipment, and finally, the mixture is put into a granulator for granulation treatment.

[0011] Preferably, tweezers and sieve tools can be used for the selection of traditional Chinese medicines in Step 1.

[0012] Preferably, the decocting and concentrating equipment in Step 3 is a decocting pot and a vacuum drying oven.

[0013] Preferably, the granulating equipment in Step 4 is a granulator.

[0014] Compared with the prior art, the beneficial effects of the present invention are:

[0015] 1. In the present invention, by selecting honeysuckle, forsythia, coptis, chrysanthemum, plantain seed, lygodium japonicum, houttuynia cordata, bupleurum, notoginseng, salvia miltiorrhiza, sophora subprostrata, and scutellaria barbata, the effects of clearing heat and detoxifying, relieving diarrhea and dysentery, cooling blood and dispelling wind, nourishing yin and moistening dryness, strengthening healthy qi and eliminating pathogenic factors, and expelling worms and killing insects of the composition can be ensured.

[0016] 2. In the present invention, by setting the composition excipients, the medicinal effects of the main traditional Chinese medicine components can be enhanced or their side effects can be improved. By setting stabilizers, solubilizers, and preservatives, the state stability and service life of the composition can be ensured. Detailed implementation manners

[0017] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without making creative efforts shall fall within the protection scope of the present invention.

[0018] Embodiment

[0019] The present invention provides the following technical solution: A veterinary drug composition containing traditional Chinese medicine ingredients, which consists of the following raw materials, with the types and proportions of the raw materials being: honeysuckle 8 - 15: forsythia 3 - 6: coptis 6 - 9: chrysanthemum 12 - 20: che xian zi 6 - 8: lygodium japonicum 7 - 10: houttuynia cordata 6 - 10: bupleurum 10 - 13: notoginseng 3 - 7: salvia miltiorrhiza 6 - 12: sophora subprostrata 6 - 8: scutellaria barbata 12 - 20. By selecting honeysuckle, forsythia, coptis, chrysanthemum, che xian zi, lygodium japonicum, houttuynia cordata, bupleurum, notoginseng, salvia miltiorrhiza, sophora subprostrata and scutellaria barbata, the effects of clearing heat and detoxifying, stopping diarrhea and dysentery, cooling blood and dispelling wind, nourishing yin and moistening dryness, strengthening the healthy qi and eliminating pathogenic factors, and expelling parasites and killing insects of the composition can be ensured.

[0020] Specifically, the excipients for preparing the composition are one or more of corn starch, fish meat, lard and soybean oil, and the additives for preparing the composition are stabilizers, solubilizers and preservatives. The stabilizer is selected as an antioxidant, the solubilizer is selected as glycerol, and the preservative is selected as sodium benzoate. By setting the excipients of the composition, the efficacy of the main traditional Chinese medicine ingredients can be enhanced or their side effects can be improved. By setting stabilizers, solubilizers and preservatives, the state stability and shelf life of the composition can be ensured.

[0021] Specifically, a preparation method of a veterinary drug composition containing traditional Chinese medicine ingredients includes the following steps. Step 1, selection of traditional Chinese medicine: Select honeysuckle, forsythia, coptis, chrysanthemum, che xian zi, lygodium japonicum, houttuynia cordata, bupleurum, notoginseng, salvia miltiorrhiza, sophora subprostrata and scutellaria barbata, and mix and process them according to the ratio of 8 - 15: 3 - 6: 6 - 9: 12 - 20: 6 - 8: 7 - 10: 6 - 10: 10 - 13: 3 - 7: 6 - 12: 6 - 8: 12 - 20.

[0022] Step 2, cleaning and soaking: After mixing the traditional Chinese medicine in appropriate proportions, clean and dry the mixed traditional Chinese medicine.

[0023] Step 3, extraction of traditional Chinese medicine: Then decoct the traditional Chinese medicine raw materials, generally controlling the time at 2 - 4 hours, and filter the decocted traditional Chinese medicine. After the filtration of the traditional Chinese medicine is completed, remove the medicinal residues, and then concentrate the traditional Chinese medicine with the help of equipment.

[0024] Step 4, mixing and preparation of the preparation: Mix the concentrated traditional Chinese medicine with corn starch, lard and soybean oil, and at the same time mix it with an antioxidant, glycerol and sodium benzoate, then uniformly mix it with the help of an auxiliary mixing device, and finally place the mixture into a granulator for granulation treatment.

[0025] Specifically, tweezers and sieve tools can be used for the selection of traditional Chinese medicine in Step 1.

[0026] Specifically, the decocting and concentrating equipment in Step 3 is a decocting pot and a vacuum drying oven. By selecting a decocting pot and a vacuum drying oven, the efficiency of decocting and concentrating can be ensured.

[0027] Specifically, the granulation device in Step 4 is a granulator. By selecting a granulator as the granulation device, the granulation efficiency of the device can be ensured.

[0028] The working principle and usage process of the present invention are as follows:

[0029] Step 1, Traditional Chinese medicine selection: Select honeysuckle, forsythia, coptis, chrysanthemum, plantain seed, lygodium japonicum, houttuynia cordata, bupleurum, notoginseng, salvia miltiorrhiza, sophora subprostrata, and scutellaria barbata, and mix them according to the ratio of 8 - 15:3 - 6:6 - 9:12 - 20:6 - 8:7 - 10:6 - 10:10 - 13:3 - 7:6 - 12:6 - 8:12 - 20.

[0030] Step 2, Cleaning and soaking: After mixing the traditional Chinese medicine in the appropriate ratio, perform cleaning and drying on the mixed traditional Chinese medicine.

[0031] Step 3, Traditional Chinese medicine extraction: Then decoct the traditional Chinese medicine raw materials, generally controlling the time within 2 - 4 hours, and filter the decocted traditional Chinese medicine. After the filtration of the traditional Chinese medicine is completed, remove the medicinal residues, and then concentrate the traditional Chinese medicine with the help of equipment.

[0032] Step 4, Mixed preparation: Mix the concentrated traditional Chinese medicine with corn starch, lard, and soybean oil, and at the same time mix it with antioxidants, glycerol, and sodium benzoate. Then use an auxiliary mixing device to mix them evenly. Finally, place the mixture into a granulator for granulation treatment.

[0033] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some of the technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A veterinary drug composition containing Chinese medicinal ingredients, comprising the following raw materials, characterized in that: The types and proportions of raw materials are as follows: Honeysuckle 8-15: Forsythia suspensa 3-6: Coptis chinensis 6-9: Chrysanthemum 12-20: Cyperus rotundus 6-8: Lygodium japonicus 7-10: Houttuynia cordata 6-10: Bupleurum 10-13: Panax notoginseng 3-7: Salvia miltiorrhiza 6-12: Sophora flavescens 6-8: Scutellaria barbata 12-20.

2. The veterinary drug composition containing Chinese medicinal ingredients according to claim 1, characterized in that: The auxiliary materials for preparing the composition are one or more of corn starch, fish meat, lard and soybean oil.

3. The veterinary drug composition containing Chinese medicinal ingredients according to claim 1, characterized in that: The additives for preparing the composition are a stabilizer, a cosolvent and a preservative. The stabilizer is an antioxidant, the cosolvent is glycerol, and the preservative is sodium benzoate.

4. A method for preparing a veterinary drug composition containing a traditional Chinese medicine component, comprising the following steps according to any one of claims 1 to 3, characterized in that: Step 1, Chinese medicine selection: select honeysuckle, forsythia, coptis, chrysanthemum, car fairy, sea sand, houttuynia, bupleurum, notoginseng, salvia miltiorrhiza, sophora flavescens and Scutellaria barbata, and mix them according to the ratio of 8-15: 3-6: 6-9: 12-20: 6-8: 7-10: 6-10: 10-13: 3-7: 6-12: 6-8: 12-20; Step 2: Cleaning and soaking: After mixing the Chinese medicines in appropriate proportions, clean and dry the mixed Chinese medicines; Step 3, Chinese medicine extraction: Then the Chinese medicine raw materials are decocted, generally for 2-4 hours, and the decocted Chinese medicine is filtered. After the Chinese medicine is filtered, the residue is removed, and then the Chinese medicine is concentrated with the help of equipment; Step 4, mixed preparation: mix the Chinese medicine concentrate with corn starch, lard and soybean oil, and at the same time mix them with antioxidants, glycerin and sodium benzoate, and then use auxiliary mixing equipment to mix them evenly, and finally put the mixture into a granulator for granulation.

5. The method for preparing a veterinary drug composition containing Chinese medicinal ingredients according to claim 4, characterized in that: In step one, tweezers and sieve tools can be used to select Chinese medicine.

6. The method for preparing a veterinary drug composition containing Chinese medicinal ingredients according to claim 4, characterized in that: The decoction and concentration equipment in step 3 is a decoction pot and a vacuum drying oven.

7. The method for preparing a veterinary drug composition containing Chinese medicinal ingredients according to claim 4, characterized in that: The granulation equipment in step 4 is a granulator.