Traditional Chinese medicine preparation for relieving cough and reducing sputum

Abstract

The invention discloses a traditional Chinese medicine preparation for relieving cough and reducing sputum, and relates to the technical field of traditional Chinese medicine preparations. The medicines are used together to achieve the effects of clearing lung, reducing phlegm, relieving cough and asthma, and promoting digestion and removing food retention. According to the long-term clinical use result, the traditional Chinese medicine preparation has remarkable treatment effects on symptoms such as cough, running nose, sneezing, nasal obstruction, laryngeal sputum, anorexia, halitosis and uncomfortable lying at night caused by phlegm-heat accumulation in the lung. The traditional Chinese medicine composition is used for treating cough-relieving and sputum-reducing symptoms according to the principles of clearing lung and reducing phlegm, relieving cough and asthma and promoting digestion and removing food retention, and is safe and effective.

Description

Technical Field

[0001] The present invention relates to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for relieving cough and resolving phlegm. Background Art

[0002] Cough caused by phlegm-dampness accumulating in the lungs is relatively common in clinical pediatric patients. Children's bodies are not fully developed, and their exterior defensive qi is not firm, so they are extremely susceptible to exogenous pathogenic factors. Also, children's spleens are often insufficient, which can easily lead to heat accumulation in the stomach and steaming upward to the lungs. When the lungs and stomach are filled with heat and are also affected by exogenous pathogenic factors, they are prone to illness. Exogenous cough is caused by the six exogenous pathogenic factors invading the lung system, causing the lung qi to be congested and not being dispersed properly; the normal function of clearing and descending is disrupted, and phlegm is generated. Endogenous injury is mostly due to the spleen deficiency generating phlegm, which blocks the airways and affects the entry and exit of lung qi, resulting in cough due to qi reversal. If a child has deficiency of both the lung and spleen, qi cannot transform body fluids, and phlegm-dampness is more likely to be generated. If phlegm-dampness accumulates in the lungs and is triggered by an exogenous pathogen, it can transform into heat, resulting in phlegm-heat cough.

[0003] Cough is a common disease in children. Traditional Chinese medicine believes that "children's lungs are often insufficient". Children's bodies are not fully developed, and their exterior defensive qi is not firm, so they are extremely susceptible to exogenous pathogenic factors and get sick. However, children are in a state of delicate yin and yang. If they have exogenous cough, it is not appropriate to use formulas that disperse the exterior and relieve the surface, or formulas that are pungent and dry and induce sweating, to prevent excessive sweating from consuming nutrient qi and damaging healthy qi. Also, "children's spleens are often insufficient". If parents lack correct feeding knowledge, feed their children out-of-season foods, or have an unreasonable diet structure, if food accumulates in the middle jiao, the spleen fails to transport and transform properly, the stomach fails to harmonize and descend, and phlegm is formed over time and accumulates in the lungs, the lungs will lose their function of dispersing and descending, resulting in cough. The main pathological factor is phlegm. Exogenous cough is caused by the six exogenous pathogenic factors invading the lung system, causing the lung qi to be congested and not being dispersed properly; the normal function of clearing and descending is disrupted, and phlegm is generated. Endogenous injury is mostly due to the spleen deficiency generating phlegm, which blocks the airways and affects the entry and exit of lung qi, resulting in cough due to qi reversal. If a child has deficiency of both the lung and spleen, qi cannot transform body fluids, and phlegm-dampness is more likely to be generated. If phlegm-dampness accumulates in the lungs and is triggered by an exogenous pathogen, it can transform into heat, resulting in phlegm-heat cough. Thus, it can be seen that treating phlegm should be the main approach for children's cough. Therefore, we propose a traditional Chinese medicine preparation for relieving cough and resolving phlegm. Summary of the Invention

[0004] The purpose of the present invention is: to solve the problems mentioned in the above background art, the present invention provides a traditional Chinese medicine preparation for relieving cough and resolving phlegm.

[0005] The present invention specifically adopts the following technical solutions to achieve the above purpose:

[0006] A traditional Chinese medicine preparation for relieving cough and resolving phlegm, the traditional Chinese medicine preparation is composed of the following parts by weight: 1 - 3 parts of indigo naturalis, 5 - 7 parts of ginkgo seeds, 5 - 7 parts of natrii sulfas, 5 - 7 parts of stir-fried semen raphani, 5 - 7 parts of honey-fried aster, 5 - 7 parts of wine-fried scutellaria baicalensis, 5 - 7 parts of magnolia officinalis, 2 - 4 parts of wine-fried rheum officinale.

[0007] Further, the traditional Chinese medicine preparation is composed of the following parts by weight: 1 part of indigo naturalis, 5 parts of ginkgo seeds, 5 parts of natrii sulfas, 5 parts of stir-fried semen raphani, 5 parts of honey-fried aster, 5 parts of wine-fried scutellaria baicalensis, 5 parts of magnolia officinalis, 2 parts of wine-fried rheum officinale.

[0008] Further, the traditional Chinese medicine preparation is composed of the following parts by weight: 2 parts of indigo naturalis, 6 parts of ginkgo seeds, 6 parts of gypsum rubrum, 6 parts of stir-fried semen raphani, 6 parts of honey-fried aster tataricus, 6 parts of wine-fried scutellaria baicalensis, 6 parts of magnolia officinalis, and 3 parts of wine-fried rheum officinale.

[0009] Further, the traditional Chinese medicine preparation is composed of the following parts by weight: 3 parts of indigo naturalis, 7 parts of ginkgo seeds, 7 parts of gypsum rubrum, 7 parts of stir-fried semen raphani, 7 parts of honey-fried aster tataricus, 7 parts of wine-fried scutellaria baicalensis, 7 parts of magnolia officinalis, and 4 parts of wine-fried rheum officinale.

[0010] Further, it includes the above-mentioned traditional Chinese medicine composition and pharmaceutically acceptable excipients, including but not limited to sucrose, benzoic acid, ethylparaben, etc.

[0011] Further, the preparation includes pills, granules, capsules, decoctions, plasters, powders and mixtures.

[0012] Further, when the preparation is a mixture, it includes the following steps: adding water to the above raw materials for extraction and concentration, adding excipients, mixing evenly, and sub-packaging to obtain the product.

[0013] Further, the preparation method of the traditional Chinese medicine preparation includes the following steps: extracting with water 2 - 3 times, with the amount of water added each time being 8 - 12 times, and the decocting time being 0.5 - 1 h each time. After combining the decoction liquids, concentrate them, add excipients, mix evenly, and sub-packaging after quality inspection to obtain the product.

[0014] Further, the preparation method of the traditional Chinese medicine preparation includes the following steps: concentrating to a relative density of 1.01 - 1.17.

[0015] The beneficial effects of the present invention are as follows:

[0016] 1. In the present invention, indigo naturalis, wine-fried scutellaria baicalensis, and gypsum rubrum: when the three drugs are used in combination, they have a significant effect of clearing heat and detoxifying, and drying dampness and purging fire, and are applicable to syndromes such as internal exuberance of heat toxin and hyperactivity of liver fire.

[0017] 2. In the formula of the present invention, wine-fried scutellaria baicalensis can also clear lung heat, and cooperate with ginkgo seeds and honey-fried aster tataricus to enhance the effect of relieving cough and resolving phlegm. It is used for clearing heat and detoxifying and drying dampness.

[0018] 3. In the present invention, ginkgo seeds astringe the lung and relieve asthma, aster tataricus moistens the lung and relieves cough, and semen raphani descends qi and dissipates phlegm. The three drugs are combined, and are applicable to cough and asthma due to lung heat and excessive phlegm with hoarse voice. It is used for relieving cough and resolving phlegm.

[0019] 4. In the present invention, magnolia officinalis promotes qi circulation and relieves distension in the middle-jiao, eliminates fullness and accumulation, and stir-fried semen raphani promotes digestion and relieves distension, descends qi and dissipates phlegm. When the two are used in combination, they promote qi circulation and relieve stagnation, soothe the middle-jiao and harmonize the stomach, and can relieve abdominal distension and fullness, and food retention and qi stagnation.

[0020] 5. The rhubarb stir-fried with wine in the present invention enhances the efficacy of the prescription in eliminating food stagnation and relieving fullness, enabling the gastrointestinal tract of children to recover faster and have a lower recurrence rate after recovery, and enabling all the herbs in the prescription to achieve the effects of clearing the lung and resolving phlegm, relieving cough and asthma, and promoting digestion and eliminating food stagnation. It is used for cough, runny nose, sneezing, nasal congestion, gurgling in the throat, anorexia, bad breath, restlessness at night, etc. caused by the syndrome of phlegm-dampness accumulating in the lung. It has a significant effect on those with excessive cough and phlegm, even accompanied by wheezing. Detailed implementation manners

[0021] In order to make the objectives, technical solutions and advantages of the present invention clearer, the following further elaborates on the present invention in combination with embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention, that is, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments.

[0022] Therefore, the following detailed description of the provided embodiments of the present invention is not intended to limit the scope of the claimed present invention, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative efforts belong to the scope of protection of the present invention.

[0023] It should be noted that relational terms such as "first" and "second" are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprising", "including" or any other variant thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or also includes elements inherent to such process, method, article or device. Without further limitation, an element defined by the statement "including one..." does not exclude the existence of additional identical elements in the process, method, article or device including the element.

[0024] The features and performance of the present invention will be further described in detail below in combination with embodiments.

[0025] The present invention provides a traditional Chinese medicine preparation for relieving cough and resolving phlegm. The traditional Chinese medicine preparation is composed of the following parts by weight: 1-3 parts of indigo naturalis, 5-7 parts of ginkgo seed, 5-7 parts of natrii sulfas, 5-7 parts of stir-fried semen raphani, 5-7 parts of aster honey-fried, 5-7 parts of scutellaria baicalensis stir-fried with wine, 5-7 parts of magnolia officinalis, and 2-4 parts of rhubarb stir-fried with wine.

[0026] Indigo naturalis, as recorded in the Chinese Pharmacopoeia (2020 Edition): Nature and flavor, and meridian tropism: salty, cold. It belongs to the liver meridian; functions and indications: clearing heat and detoxifying, cooling blood and removing macules, purging fire and suppressing fright;

[0027] Ginkgo Seed, as recorded in the Chinese Pharmacopoeia (2020 Edition): Nature, flavor, and meridian tropism: sweet, bitter, astringent, neutral; toxic. It pertains to the lung and kidney meridians; functions and indications: astringing the lung to relieve asthma, stopping leukorrhea and reducing urination;

[0028] South Frigid Calcite, as recorded in the Sichuan Provincial Standard for Processing of Traditional Chinese Medicine Decoction Pieces (2002 Edition): Nature, flavor, and meridian tropism: pungent, salty, cold. It pertains to the heart and stomach meridians; functions and indications: clearing heat and reducing fire, removing vexation and quenching thirst;

[0029] Fried Semen Raphani, as recorded in the Chinese Pharmacopoeia (2020 Edition): Nature, flavor, and meridian tropism: pungent, sweet, neutral. It pertains to the lung, spleen, and stomach meridians; functions and indications: promoting digestion and relieving distension, descending qi and resolving phlegm;

[0030] Honey-fried Aster Root, as recorded in the Chinese Pharmacopoeia (2020 Edition): Nature, flavor, and meridian tropism: pungent, bitter, warm. It pertains to the lung meridian; functions and indications: moistening the lung and lowering qi, resolving phlegm and relieving cough;

[0031] Wine-fried Scutellaria Root, as recorded in the Chinese Pharmacopoeia (2020 Edition): Nature, flavor, and meridian tropism: bitter, cold. It pertains to the lung, gallbladder, spleen, large intestine, and small intestine meridians; functions and indications: clearing heat and drying dampness, purging fire and detoxifying, stopping bleeding, and preventing miscarriage;

[0032] Magnolia Bark, as recorded in the Chinese Pharmacopoeia (2020 Edition): Nature, flavor, and meridian tropism: bitter, pungent, warm. It pertains to the spleen, stomach, lung, and large intestine meridians; functions and indications: drying dampness and resolving phlegm, descending qi and relieving fullness;

[0033] Wine-fried Rhubarb, as recorded in the Chinese Pharmacopoeia (2020 Edition): Nature, flavor, and meridian tropism: bitter, cold. It pertains to the spleen, stomach, large intestine, liver, and pericardium meridians; functions and indications: purging downward to attack accumulation, clearing heat and purging fire, cooling blood and detoxifying, removing stasis and dredging meridians, promoting diuresis and removing jaundice.

[0034] In this example, preferably, the preparation method of the traditional Chinese medicine preparation includes the following steps: extracting with water 2 - 3 times, with the amount of water added each time being 8 - 12 times, and the decocting time being 0.5 - 1 h each time. After combining the decoction liquids, concentrate to an appropriate volume, a concentrated liquid with a relative density of 1.01 - 1.17, add excipients such as sucrose, mix evenly, and after passing the quality inspection, package it to obtain the product.

[0035] Example 1

[0036] The composition of a traditional Chinese medicine preparation for relieving cough and resolving phlegm: 2 parts of Indigo Naturalis, 6 parts of Ginkgo Seed, 6 parts of South Frigid Calcite, 6 parts of Fried Semen Raphani, 6 parts of Honey-fried Aster Root, 6 parts of Wine-fried Scutellaria Root, 6 parts of Magnolia Bark, 3 parts of Wine-fried Rhubarb;

[0037] In this example, preferably, it includes the above-mentioned traditional Chinese medicine composition and pharmaceutically acceptable excipients, including but not limited to sucrose, benzoic acid, ethylparaben, etc.

[0038] In this example, preferably, the preparation includes pills, granules, capsules, decoctions, plasters, powders, and mixtures.

[0039] When the preparation is a mixture, the preparation method includes the following steps: extracting with water 2 - 3 times, with the amount of water added each time being 8 - 12 times, the decocting time being 0.5 - 1 h each time, combining the decocted liquids and concentrating to an appropriate volume, a concentrated liquid with a relative density of 1.01 - 1.17, adding excipients such as sucrose, mixing evenly, and performing sub-packaging after passing the quality inspection to obtain the product.

[0040] Example 2

[0041] The parts composition of a traditional Chinese medicine preparation for relieving cough and resolving phlegm: 1 part of indigo naturalis, 5 parts of ginkgo seed, 5 parts of natrii sulfas, 5 parts of stir-fried semen raphani, 5 parts of honey-fried aster tataricus, 5 parts of wine-fried scutellaria baicalensis, 5 parts of magnolia officinalis, 2 parts of wine-fried rheum officinale.

[0042] In this example, preferably, it includes the above traditional Chinese medicine composition and pharmaceutically acceptable excipients, including but not limited to sucrose, benzoic acid, ethylparaben, etc.

[0043] In this example, preferably, the preparation includes pills, granules, capsules, decoctions, plasters, powders and mixtures.

[0044] When the preparation is a mixture, the preparation method includes the following steps: extracting with water 2 - 3 times, with the amount of water added each time being 8 - 12 times, the decocting time being 0.5 - 1 h each time, combining the decocted liquids and concentrating to an appropriate volume, a concentrated liquid with a relative density of 1.01 - 1.17, adding excipients such as sucrose, mixing evenly, and performing sub-packaging after passing the quality inspection to obtain the product.

[0045] Example 3

[0046] The parts composition of a traditional Chinese medicine preparation for relieving cough and resolving phlegm: 3 parts of indigo naturalis, 7 parts of ginkgo seed, 7 parts of natrii sulfas, 7 parts of stir-fried semen raphani, 7 parts of honey-fried aster tataricus, 7 parts of wine-fried scutellaria baicalensis, 7 parts of magnolia officinalis, 4 parts of wine-fried rheum officinale.

[0047] In this example, preferably, it includes the above traditional Chinese medicine composition and pharmaceutically acceptable excipients, including but not limited to sucrose, benzoic acid, ethylparaben, etc.

[0048] In this example, preferably, the preparation includes pills, granules, capsules, decoctions, plasters, powders and mixtures.

[0049] When the preparation is a mixture, the preparation method includes the following steps: extracting with water 2 - 3 times, with the amount of water added each time being 8 - 12 times, the decocting time being 0.5 - 1 h each time, combining the decocted liquids and concentrating to an appropriate volume, a concentrated liquid with a relative density of 1.01 - 1.17, adding excipients such as sucrose, mixing evenly, and performing sub-packaging after passing the quality inspection to obtain the product.

[0050] Typical cases:

[0051] Case 1: Chen, female, 7 years old. She visited the doctor on June 2, 2022 due to "repeated cough for 15 days". Before visiting our hospital, she had visited "Baoshihua Hospital" and was diagnosed with "bronchopneumonia". She was hospitalized for 8 days. After the symptoms improved and she was discharged, she continued to take oral medications, but the effect was not good. So she was referred to our hospital. The symptoms at the time of visiting were: intermittent cough in the early morning, more cough during the day, not much phlegm, itchy throat, bad breath, poor appetite, frequently turning over and kicking the quilt while sleeping at night, and sweating a lot with wet hair. The traditional Chinese medicine diagnosis was phlegm-dampness accumulating in the lungs syndrome, and the traditional Chinese medicine preparation in this application was prescribed for her. After taking it for 7 days, she came for a follow-up visit. She reported that she only had an occasional choking cough 1 - 2 times at night, and no cough at other times.

[0052] Case 2: Lai, male, 3 years old. On November 3, 2023, he visited the doctor due to "cough for 6 days". The symptoms were: no cough during sleep, more cough in the early morning and after exercise, slightly difficult to cough, frequently turning over and kicking the quilt while sleeping at night, sweating a lot, red lips, red tongue with white and greasy coating. The traditional Chinese medicine diagnosis was heat accumulation in the lung and stomach syndrome, and the western medicine diagnosis was acute bronchitis. The traditional Chinese medicine preparation in this application was prescribed for him. After taking it for 7 days, he came for a follow-up visit. The coughing, expectoration, and runny nose stopped, the redness of the lips was relieved, and the sweating during sleep was significantly relieved.

[0053] Case 3: Fu, male, 5 years old. On January 8, 2022, he visited the doctor due to "long-term poor appetite and cough for 4 days". The symptoms were: more cough in the early morning, occasional cough during the day, 2 - 3 times each time, slightly bad breath, poor appetite, liking to lie prone at night, red lips, red tongue with white and greasy coating, and follicular hyperplasia on the posterior pharyngeal wall. The traditional Chinese medicine diagnosis was heat accumulation in the lung and stomach syndrome, and the western medicine diagnosis was acute bronchitis. The traditional Chinese medicine preparation in this application was prescribed for him. After taking it for 7 days, he came for a follow-up visit. Only a small amount of cough in the early morning was seen, there was phlegm in the throat, the appetite increased, the redness of the lips was relieved, and the tongue was light red with slightly white and greasy coating.

[0054] The above description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be obvious to those skilled in the art, and the general principles defined herein can be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the broadest scope consistent with the principles and novel features disclosed herein.

Claims

1. A Chinese medicine preparation for relieving cough and reducing phlegm, characterized in that: The Chinese medicine preparation is divided into the following parts Composition: 1-3 parts of Indigo, 5-7 parts of Ginkgo, 5-7 parts of Nanhan Water Stone, 5-7 parts of stir-fried Radish Seed, 5-7 parts of Honey-roasted Aster, 5-7 parts of Wine-roasted Scutellaria, 5-7 parts of Magnolia Bark, 2-4 parts of Wine-roasted Rhubarb.

2. A Chinese medicine preparation for relieving cough and reducing phlegm according to claim 1, characterized in that: The Chinese medicine preparation is divided into the following parts Composition: 1 part of Indigo, 5 parts of Ginkgo, 5 parts of Nanhan Water Stone, 5 parts of stir-fried Radish Seed, 5 parts of Honey-roasted Aster, 5 parts of Wine-roasted Scutellaria, 5 parts of Magnolia Bark, 2 parts of Wine-roasted Rhubarb.

3. A Chinese medicine preparation for relieving cough and reducing phlegm according to claim 1, characterized in that: The Chinese medicine preparation is divided into the following parts Composition: 2 parts of Indigo, 6 parts of Ginkgo, 6 parts of Nanhan Water Stone, 6 parts of stir-fried Radish Seed, 6 parts of Honey-roasted Aster, 6 parts of Wine-roasted Scutellaria, 6 parts of Magnolia Bark, 3 parts of Wine-roasted Rhubarb.

4. A Chinese medicine preparation for relieving cough and reducing phlegm according to claim 1, characterized in that: The Chinese medicine preparation is divided into the following parts Composition: 3 parts of Indigo, 7 parts of Ginkgo, 7 parts of Nanhan Water Stone, 7 parts of stir-fried Radish Seed, 7 parts of Honey-roasted Aster, 7 parts of Wine-roasted Scutellaria, 7 parts of Magnolia Bark, 4 parts of Wine-roasted Rhubarb.

5. A Chinese medicine preparation for relieving cough and reducing phlegm according to claim 1, characterized in that: The invention comprises the Chinese medicine composition according to claim 1 to claim 4 and pharmaceutically acceptable excipients, including but not limited to sucrose, benzoic acid, ethyl hydroxybenzoate and the like.

6. A Chinese medicine preparation for relieving cough and reducing phlegm according to claim 5, characterized in that: The preparations include pills, granules, capsules, decoctions, pastes, powders and mixtures.

7. The method for preparing a Chinese medicine composition for relieving cough and reducing phlegm according to claim 6, characterized in that: When the preparation is a mixture, the steps include: extracting and concentrating the above raw materials with water, adding auxiliary materials, mixing evenly, and packaging to obtain the mixture.

8. The method for preparing a Chinese medicine composition for relieving cough and reducing phlegm according to claim 7, characterized in that Extract with water 2 to 3 times, adding 8 to 12 times the amount of water each time, and the decoction time is 0.5 to 1 hour each time. Combine the decoctions and concentrate them, add auxiliary materials, mix evenly, and package after quality inspection.

9. The method for preparing a Chinese medicine preparation composition for relieving cough and reducing phlegm according to claim 7, characterized in that: Concentrate to a relative density of 1.01 to 1.17.