Application of tartary buckwheat antioxidant peptide as whitening and anti-aging product

Abstract

The invention provides an application of a tartary buckwheat antioxidant peptide as a whitening and anti-aging product, and the tartary buckwheat antioxidant peptide (SEQ ID NO: 1) is used for increasing the content of nicotinamide adenine dinucleotide, and is used for preparing a whitening and anti-aging food or a whitening and anti-aging beauty product. By increasing the content of nicotinamide adenine dinucleotide, the tartary buckwheat antioxidant peptide disclosed by the invention can be used as a whitening and anti-aging food or a beautifying product to achieve the effects of whitening skin and delaying aging.

Description

Technical Field

[0001] The present invention belongs to the technical field of the application of tartary buckwheat antioxidant peptides, and specifically relates to the application of a tartary buckwheat antioxidant peptide as a whitening and anti-aging product. Background Art

[0002] With the improvement of living standards, consumers' demand for delaying aging and maintaining a young skin state is increasing day by day, and the market for whitening and anti-aging health care products and skin care products is showing a booming development trend.

[0003] Nicotinamide adenine dinucleotide (NAD + ) is a coenzyme that plays a key role in cellular energy metabolism and is closely related to beauty and anti-aging. NAD + helps whiten the skin by reducing melanin production and pigmentation and promoting the renewal and repair of skin cells. As people age, the content of NAD + gradually decreases, resulting in blocked cellular energy metabolism and the appearance of aging signs on the skin. Supplementing NAD + can improve cellular energy metabolism, promote the production of collagen, delay skin aging, and whiten the skin. Summary of the Invention

[0004] The technical problem to be solved by the present invention is to provide an application of a tartary buckwheat antioxidant peptide as a whitening and anti-aging product in view of the deficiencies of the above-mentioned prior art. This tartary buckwheat antioxidant peptide can be used to prepare foods or beauty products that can increase the content of nicotinamide adenine dinucleotide, and has broad application prospects.

[0005] To solve the above technical problem, the technical solution adopted by the present invention is: an application of a tartary buckwheat antioxidant peptide as a whitening and anti-aging product, wherein the tartary buckwheat antioxidant peptide is used to increase the content of nicotinamide adenine dinucleotide and is used to prepare foods for whitening and anti-aging or beauty products for whitening and anti-aging; the amino acid sequence of the tartary buckwheat antioxidant peptide is as shown in SEQ ID NO:1.

[0006] Preferably, the foods for whitening and anti-aging or beauty products for whitening and anti-aging include acceptable carriers and excipients.

[0007] Preferably, the foods for whitening and anti-aging or beauty products for whitening and anti-aging contain one or more carriers acceptable in pharmaceuticals or skin care products that include the amino acid sequence of the tartary buckwheat antioxidant peptide.

[0008] Preferably, using the tartary buckwheat antioxidant peptide as an active ingredient, it is made into any dosage form of tablets, capsules, powders, mixtures, pills, sprays, granules, capsules, oral liquids, injections, and any skin care product type of facial cleanser, creams, lotions, toners or masks.

[0009] The present invention has the following advantages compared with the prior art:

[0010] The tartary buckwheat antioxidant peptide (SEQ ID NO: 1) of the present invention achieves the purposes of whitening and anti-aging by increasing the content of nicotinamide adenine dinucleotide. The present invention provides a new example for the development of whitening and anti-aging health foods or beauty products and the application of tartary buckwheat antioxidant peptides.

[0011] The present invention will be further described in detail below with reference to the accompanying drawings and embodiments. Description of the Drawings

[0012] Figure 1 In the oxidative damage cell model of Example 2 of the present invention, the tartary buckwheat antioxidant peptide AFYRW increases the content of nicotinamide adenine dinucleotide (NAD + ). Detailed Embodiments

[0013] Example 1

[0014] The preparation method of the tartary buckwheat antioxidant peptide (SEQ ID NO: 1) in the present invention can be found in Chinese Patent CN109336953B. The tartary buckwheat antioxidant peptide in the present invention is the tartary buckwheat antioxidant peptide P3 prepared in Chinese Patent CN109336953B, and the tartary buckwheat antioxidant peptide is named tartary buckwheat antioxidant peptide AFYRW in the present invention.

[0015] The application of tartary buckwheat antioxidant peptide AFYRW as a whitening and anti-aging product, the tartary buckwheat antioxidant peptide is used to increase the content of nicotinamide adenine dinucleotide, and is used to prepare foods for whitening and anti-aging or beauty products for whitening and anti-aging. Example 2 is an experiment for detecting the content of nicotinamide adenine dinucleotide (NAD + ).

[0016] The foods for whitening and anti-aging or beauty products for whitening and anti-aging include acceptable carriers and excipients.

[0017] The foods for whitening and anti-aging or beauty products for whitening and anti-aging contain one or more pharmaceutically acceptable carriers included in the amino acid sequence of the tartary buckwheat antioxidant peptide AFYRW.

[0018] Using tartary buckwheat antioxidant peptide AFYRW as an active ingredient, it can be made into any dosage form of tablets, capsules, powders, mixtures, pills, sprays, granules, capsules, oral liquids, injections, and any type of skin care product such as facial cleansers, creams, lotions, toners or masks.

[0019] Example 2

[0020] This example is about the effect of tartary buckwheat active peptide AFYRW on the content of nicotinamide adenine dinucleotide (NAD + ).

[0021] Using hydrogen peroxide (H2O2) to induce oxidative damage in human immortalized epidermal cells (HaCaT) to construct an oxidative damage cell model with down-regulated NAD + content.

[0022] The experiment was divided into four groups:

[0023] Control: Control group.

[0024] H2O2: Oxidative damage cell model group.

[0025] H2O2+AFYRW 50: Low-concentration AFYRW treatment group, adding 50 μg / mL AFRYW to the oxidative damage cell model (H2O2).

[0026] H2O2+AFYRW 100: High-concentration AFYRW treatment group, adding 100 μg / mL AFRYW to the oxidative damage cell model (H2O2).

[0027] Detect the content of nicotinamide adenine dinucleotide (NAD+) in cells of each group to evaluate the whitening and antioxidant effects of tartary buckwheat active peptide AFYRW. As Figure 1 shown, compared with the control group (Control), the content of nicotinamide adenine dinucleotide (NAD+) in the oxidative damage cell model group (H2O2) decreased significantly, while the low-concentration AFYRW treatment group (H2O2+AFYRW50) and the high-concentration AFYRW treatment group (H2O2+AFYRW 100) could effectively up-regulate the content of nicotinamide adenine dinucleotide (NAD+) in it, indicating that AFYRW effectively increased the content of nicotinamide adenine dinucleotide (NAD+) in oxidative damage cells.

[0028] In summary, the tartary buckwheat antioxidant peptide AFYRW of the present invention achieves the purposes of whitening and anti-aging by increasing the content of nicotinamide adenine dinucleotide, and is used for preparing foods for whitening and anti-aging or beauty products for whitening and anti-aging.

[0029] The above are only the preferred embodiments of the present invention and do not impose any limitations on the present invention. Any simple modifications, changes, and equivalent variations made to the above embodiments according to the technical essence of the invention still fall within the protection scope of the technical solution of the present invention.

Claims

1. Application of tartary buckwheat antioxidant peptide as a whitening and anti-aging product, characterized in that: The tartary buckwheat antioxidant peptide is used to increase the content of nicotinamide adenine dinucleotide and is used to prepare whitening and anti-aging food or whitening and anti-aging beauty products; the amino acid sequence of the tartary buckwheat antioxidant peptide is shown in SEQ ID NO:

1.

2. The use of a tartary buckwheat antioxidant peptide as a whitening and anti-aging health food or beauty product according to claim 1, characterized in that: The whitening and anti-aging food or the whitening and anti-aging beauty product comprises an acceptable carrier and excipient.

3. The use of a tartary buckwheat antioxidant peptide as a whitening and anti-aging health food or beauty product according to claim 1, characterized in that: The food for whitening and anti-aging or the beauty product for whitening and anti-aging contains one or more medicines or acceptable carriers in skin care products containing the amino acid sequence of the bitter buckwheat antioxidant peptide.

4. Use of a tartary buckwheat antioxidant peptide according to any one of claims 1 to 3 as a whitening and anti-aging health food or beauty product, characterized in that: The tartary buckwheat antioxidant peptide is used as an active ingredient to prepare any dosage form of tablets, capsules, powders, mixtures, pills, sprays, granules, capsules, oral liquids, injections, and any skin care product type of facial cleansers, creams, lotions, toners or facial masks.

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