Dual plasma exchange system

Abstract

The invention discloses a dual plasma exchange system which comprises a first plasma separator, a second plasma separator, a first plasma component separator, a second plasma component separator, two groups of flushing fluid bags and a plurality of groups of pipelines, the two groups of flushing fluid bags are respectively communicated with the first plasma separator, the second plasma separator, the first plasma component separator and the second plasma component separator through pipelines, the flow rate of liquid in the pipelines is controlled by a pump body, and a flow divider valve is arranged in the pipelines; the clamping exhaust mechanism exhausts bubbles in the separator through shaking, rotating and vibrating; after the first plasma separator and the first plasma component separator separate toxins in the blood of the patient, the purified blood flows back to the body of the patient through a pipeline in cooperation with replenishing liquid, the physical labor of medical staff can be effectively relieved, and the continuity of plasma exchange treatment is improved; the treatment pause caused by the blockage of the separator is reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of plasma exchange, and particularly relates to a double plasma exchange system. Background Art

[0002] The double plasma exchange system mainly utilizes the molecular membrane structure technology to filter the blood in the human body through two - stage filtration, filter out macromolecular pathogenic factors such as low - density lipoprotein, very - low - density lipoprotein, immunoglobulin, immune complexes, etc., and is equipped with a replenishing solution to return the purified blood to the body to achieve the effect of blood purification.

[0003] Among them, the plasma separator and the plasma component separator used belong to consumables, and different patients need to use them separately and replace them after a single treatment; during the treatment process, the blood may coagulate to form thrombus after being pumped out, causing the separator to be blocked. Therefore, heparin anticoagulant needs to be added, and usually a larger - sized puncture needle is used. When the patient's blood vessels are relatively fragile or a child is being treated, a smaller needle cannot obtain the required blood flow rate, and the dosage of the anticoagulant also needs to be controlled, otherwise complications are likely to occur; so the separator may still be blocked, and the treatment needs to be suspended for replacement or flushing. At the same time, the clamp of the plasma separator in the existing equipment can only perform regular and slow shaking, and its effect on discharging air bubbles is very limited. Usually, it still needs to be manually removed and subjected to certain beating and rapid rotation steps to achieve better results.

[0004] For example, the extracorporeal circulation system for double plasma exchange with the publication number CN114225140A has a structure including a blood pump, a primary plasma separator A, a blood cell storage bag, a blood collection bag, a secondary plasma separator A, a first plasma storage bag, a plasma purification device, a waste liquid collection bag, and a second plasma storage bag. The liquid inlet of the blood pump is connected to a first pipeline. Although it is provided with a spare separator for use when the separator is blocked, it does not have an additional flushing channel. If the separator is blocked again, the treatment can only be suspended for handling, and it also cannot solve the problem of inconvenient air - bubble discharge in the separator during the pre - flushing stage.

[0005] Therefore, the present application designs a double plasma exchange system that can automatically discharge air bubbles from the separator, switch the separator during the treatment process, and dredge the blocked separator. Summary of the Invention

[0006] The purpose of the present invention is to provide a double plasma exchange system, aiming to solve the above - mentioned existing problems.

[0007] To achieve the above object, the present invention provides the following technical solution: a double plasma exchange system, comprising a first plasma separator, a second plasma separator, a first plasma component separator, a second plasma component separator, two groups of flushing solution bags and several groups of pipelines; the two groups of flushing solution bags are respectively connected to the first plasma separator, the second plasma separator, the first plasma component separator and the second plasma component separator through pipelines, the liquid flow rate in the pipelines is controlled by a pump body, and a flow dividing valve is arranged in the pipelines; all separators are clamped by a clamping and exhaust mechanism, and the clamping and exhaust mechanism discharges the bubbles in the separators through shaking, rotating and vibrating; and assists the flushing solution to dredge the blockage. After the first plasma separator and the first plasma component separator separate the toxins in the patient's blood, the purified blood is returned to the patient's body through the pipeline with a supplementary solution.

[0008] By setting the second plasma separator, the second plasma component separator, cooperating with the two groups of flushing solution bags, the separate pipelines and the flow dividing valve, when a blockage occurs, the used separator can be switched, and the blocked separator can be dredged by the flushing solution in cooperation with the movement of the clamping and exhaust mechanism, so that the blocked separator can be used as a new standby separator waiting for use, preventing the suspension of treatment caused by secondary blockage during the treatment process, effectively reducing the labor intensity of medical staff and ensuring the continuity of treatment.

[0009] Furthermore, it further comprises a waste liquid bag and a supplementary solution bag, the waste liquid bag is respectively connected to the first plasma separator, the second plasma separator, the first plasma component separator and the second plasma component separator through pipelines; the supplementary solution bag is connected to the pipeline return place. It further comprises a machine body, the clamping and exhaust mechanism is fixedly connected to the machine body, a hanging bottle rack is arranged at the upper end of the machine body, the pump body is fixedly connected to the machine body, and the pipeline is detachably connected to the machine body. An automatic control system is arranged on the upper side of the machine body, the automatic control system directly controls the operation of the pump body and the flow dividing valve, and a driving mechanism is also arranged in the machine body, and the driving mechanism is in transmission connection with the clamping and exhaust mechanism.

[0010] Furthermore, the driving mechanism comprises a motor, a rotating rod, four groups of driving worms, a heating worm, four groups of worm wheels, an independent driver and a heating component; the rear end of the motor is bolted to the inner wall of the machine body, the output end of the motor is inserted into the rotating rod, and the side of the rotating rod away from the motor penetrates through the machine body and is rotatably connected to the machine body; the driving worms and the heating worm are sleeved on the outer periphery of the rotating rod and are rotationally connected to the rotating rod with a limit to prevent the driving worms from having a horizontal displacement, the heating worm is positioned on the part of the rotating rod outside the machine body, the independent driver is fixedly connected to the outer periphery of the rotating rod, the worm wheels are in transmission connection with the driving worms, the worm wheels are rotatably connected to the inside of the machine body, and a vertical rod is fixedly arranged at the upper end of the worm wheels. The independent driver comprises an electromagnetic pin and a clamping pin, the clamping pin is fixedly connected to the outer periphery of the rotating rod, and the electromagnetic pin is slidably connected to the inner walls of the driving worms and the heating worm.

[0011] By means of the provided driving mechanism, a single drive can be used to separately control the clamping and exhaust mechanisms corresponding to each separator to operate, so that it does not occupy too much internal space of the machine body.

[0012] Furthermore, the heating component includes a heating wire and an opening / closing cover body. The heating wire is arranged inside the heating worm gear. The opening / closing cover body is rotatably connected to the outer wall of the machine body. The opening / closing cover body is a two-section structure that is snap-connected to each other. Wire passing holes are provided at both the upper and lower parts of the opening / closing cover body. A wire clamping buckle is arranged in the middle screw groove of the heating worm gear.

[0013] By means of the provided heating worm gear and heating component, the return blood pipeline can be clamped on the heating worm gear through the wire clamping buckle. When the heating worm gear rotates, the pipelines above and below can be wound and clamped into the spiral groove inside, and the heating wire is used to heat the blood, making the heating more uniform, effectively improving the heating efficiency and uniformity of the returned blood, and improving the comfort of the patient.

[0014] Furthermore, the clamping and exhaust mechanism includes an outer clamping plate, an inner clamping plate, a plurality of groups of springs, a hoop, a swinging component, and a rotating and vibrating component. Both the outer clamping plate and the inner clamping plate are open arc-shaped structures. The lower side wall of the inner clamping plate is rotatably connected to the outer clamping plate. The outer wall of the inner clamping plate is connected to the inner wall of the outer clamping plate through a spring. One end of the hoop is rotatably connected to the opening of the inner clamping plate, and the other end of the hoop is snap-connected to the inner clamping plate. Cushion layers are arranged on the inner sides of both the inner clamping plate and the hoop.

[0015] Furthermore, the swinging mechanism includes a rotating column, an arc-shaped sliding groove, a sliding block, a limiting track, and a first connecting rod. One end of the rotating column is fixedly connected to the rear end of the outer clamping plate. The rotating column is rotatably connected to the inner wall of the machine body. The arc-shaped sliding groove is opened on the outer wall of the rotating column. The lower end of the sliding block is slidably connected to the rotating column through the arc-shaped sliding groove. The upper end of the sliding block is slidably connected to the limiting track. The limiting track is fixedly connected to the inner wall of the machine body. The upper end of the sliding block is simultaneously rotatably connected to the first connecting rod. The end of the first connecting rod away from the sliding block is rotatably connected to the upper end of the vertical rod.

[0016] Furthermore, the rotating and vibrating component includes a rotating disk, a toothless gear, a rotating tooth, and a second connecting rod. The upper end of the rotating disk is fixedly connected to the lower end of the inner clamping plate. The rear end of the rotating tooth is rotatably connected to the side circumference of the rotating disk. The lower end of the toothless gear is rotatably connected to the internal structure of the machine body. The teeth of the toothless gear are in contact with the rotating tooth. One end of the second connecting rod is rotatably connected to the upper part of the toothless gear, and the other end of the second connecting rod is rotatably connected to the lower part of the vertical rod.

[0017] By means of the provided clamping and exhaust mechanism driven by the driving mechanism, the inner clamping plate is simultaneously subjected to rocking, rotating, and vibrating synchronous motions, so that the inner clamping plate can drive the separator to quickly discharge air bubbles. When the separator is blocked, the separator passage can be quickly opened through the movement in cooperation with the flushing of the flushing liquid, preparing for the subsequent treatment work. There is no need for manual exhaust and dredging, effectively improving the working efficiency of the system and reducing the physical labor of medical staff.

[0018] Compared with the prior art, the present invention has the following beneficial effects:

[0019] By providing a second plasma separator, a second plasma component separator, two sets of flushing fluid bags, a separate pipeline and a flow dividing valve, when a blockage occurs, the used separator can be switched, and the blocked separator can be dredged by the cooperation of the flushing fluid and the movement of the clamping and exhaust mechanism, so that the blocked separator can be used as a new standby separator waiting for use, preventing the suspension of treatment caused by secondary blockage during the treatment process, effectively reducing the labor intensity of medical staff, and ensuring the continuity of treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following will briefly introduce the drawings required for the description of the embodiments. Obviously, the drawings in the following description are only the preferred embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0021] Figure 1 It is a schematic diagram of the overall structure of a dual plasma exchange system of the present invention;

[0022] Figure 2 It is a schematic diagram of the body and the clamping and exhaust mechanism of a dual plasma exchange system of the present invention;

[0023] Figure 3 It is a schematic diagram of the driving mechanism of a dual plasma exchange system of the present invention;

[0024] Figure 4 It is a schematic diagram of an independent driver of a dual plasma exchange system of the present invention;

[0025] Figure 5 It is a schematic diagram of the heating component of a dual plasma exchange system of the present invention;

[0026] Figure 6 It is a cross-sectional view of the heating component of a dual plasma exchange system of the present invention;

[0027] Figure 7 It is a schematic diagram of the clamping and exhaust mechanism of a dual plasma exchange system of the present invention;

[0028] Figure 8 It is a schematic diagram of the swing component of a dual plasma exchange system of the present invention;

[0029] Figure 9 It is a connection diagram of the swing component of a dual plasma exchange system of the present invention;

[0030] Figure 10Schematic diagram of the rotating vibration component of a dual plasma exchange system according to the present invention;

[0031] Figure 11 Connection schematic diagram of the rotating vibration component of a dual plasma exchange system according to the present invention.

[0032] In the figure: 110 - First plasma separator; 120 - Second plasma separator; 130 - First plasma component separator; 140 - Second plasma component separator; 150 - Flushing liquid bag; 160 - Pipeline; 161 - Shunt valve; 170 - Pump body;

[0033] 180 - Clamping and exhaust mechanism; 181 - Outer splint; 182 - Inner splint; 183 - Spring; 184 - Hoop; 185 - Swing component; 1851 - Rotating column; 1852 - Arc-shaped chute; 1853 - Slide block; 1854 - Limit track; 1855 - First connecting rod; 186 - Rotating vibration component; 1861 - Rotating disk; 1862 - Toothless gear; 1863 - Rotating tooth; 1864 - Second connecting rod; 187 - Cushion layer;

[0034] 190 - Waste liquid bag; 200 - Supplementary liquid bag;

[0035] 210 - Machine body; 211 - Infusion bottle rack; 212 - Automatic control system;

[0036] 220 - Driving mechanism; 221 - Motor; 222 - Rotating rod; 223 - Driving worm; 224 - Heating worm; 225 - Worm gear; 2251 - Upright rod; 226 - Independent driver; 2261 - Electromagnetic pin; 2262 - Pin; 227 - Heating component; 2271 - Open and close cover body; 2272 - Wiring hole. Detailed implementation manner

[0037] In order to more easily understand the structure of the present invention and the functional features and advantages that can be achieved, the preferred embodiments of the present invention will be described in detail below in conjunction with the drawings as follows:

[0038] As Figures 1 to 11As shown in the figure, the present application proposes a double plasma exchange system, which includes a first plasma separator 110, a second plasma separator 120, a first plasma component separator 130, a second plasma component separator 140, two groups of flushing fluid bags 150, and several groups of pipelines 160; the two groups of flushing fluid bags 150 are respectively connected to the first plasma separator 110, the second plasma separator 120, the first plasma component separator 130, and the second plasma component separator 140 through the pipelines 160, and the liquid flow rate in the pipelines 160 is controlled by a pump body 170. A flow dividing valve 161 is provided in the pipelines 160; all separators are clamped by a clamping and exhaust mechanism 180, and the clamping and exhaust mechanism 180 discharges the air bubbles in the separators through shaking, rotating and vibrating; and assists the flushing fluid to dredge. The first plasma separator 110 and the first plasma component separator 130 filter the patient's blood and mix it with a replenishing fluid, and then return the purified blood to the patient's body through the pipeline 160.

[0039] See Figure 1 , it further includes a waste liquid bag 190 and a replenishing fluid bag 200. The waste liquid bag 190 is respectively connected to the first plasma separator 110, the second plasma separator 120, the first plasma component separator 130, and the second plasma component separator 140 through the pipeline 160; the replenishing fluid bag 200 is connected to the return place of the pipeline 160.

[0040] One of the flushing fluid bags 150 is connected to the first plasma separator 110 and the second plasma separator 120, and then connected to the waste liquid bag 190 through the pipeline 160. The other flushing fluid bag 150 is connected to the first plasma component separator 130 and the second plasma component separator 140, and then connected to the waste liquid bag 190. The flow dividing valve 161 enables the flushing fluid to respectively flush the four separators without affecting the normal progress of the treatment. When a separator is blocked, the flow dividing valve 161 is activated to make the blood channel flow through a different separator. The flushing fluid bag 150 injects flushing fluid into the blocked separator for flushing and dredging, and conducts the waste liquid to the waste liquid bag 190.

[0041] See Figure 2 , it further includes a machine body 210. The clamping and exhaust mechanism 180 is fixedly connected to the machine body 210. A hanging bottle rack 211 is provided at the upper end of the machine body 210. The pump body 170 is fixedly connected to the machine body 210. The pipeline 160 is detachably connected to the machine body 210. The hanging bottle rack 211 is used to hang the flushing fluid bag 150, the waste liquid bag 190 and the replenishing fluid bag 200. The pump body 170 is provided in several groups at different positions of the pipeline 160. The pipeline 160 adopts a detachable disposable pipeline 160, and a pipeline 160 bayonet is provided on the machine body 210.

[0042] See Figure 2 and Figure 3An automatic control system 212 is disposed on the upper side of the machine body 210 , and the automatic control system 212 directly controls the operation of the pump body 170 and the diverter valve 161 . A driving mechanism 220 is also disposed in the machine body 210 , and the driving mechanism 220 is transmission-connected to the clamping exhaust mechanism 180 .

[0043] As another example, Figures 2 to 6 As shown, the driving mechanism 220 includes a motor 221, a rotating rod 222, four sets of driving worms 223, a heating worm 224, four sets of worm gears 225, an independent driver 226 and a heating component 227; the rear end of the motor 221 is bolted to the inner wall of the body 210, the output end of the motor 221 is plugged into the rotating rod 222, the side of the rotating rod 222 away from the motor 221 passes through the body 210 and is rotatably connected to the body 210; the driving worm 223 and the heating worm 224 are sleeved on the outer periphery of the rotating rod 222 and are rotatably connected to the rotating rod 222 with a limited position to prevent the driving worm 223 from horizontal displacement, the heating worm 224 is positioned at the part of the rotating rod 222 located outside the body 210, the independent driver 226 is fixedly connected to the outer periphery of the rotating rod 222, the worm gear 225 is transmission-connected to the driving worm 223, the worm gear 225 is rotatably connected to the inside of the body 210, and a vertical rod 2251 is fixedly arranged on the upper end of the worm gear 225.

[0044] When the separator needs to be pre-flushed or the separator is clogged and needs to be cleared, the motor 221 starts to drive the rotating rod 222 to rotate, and the independent driver 226 is used to make the rotating rod 222 drive the specific driving worm 223 to rotate, and then drive the worm wheel 225 meshing with the worm to rotate, and the rotation of the worm wheel 225 drives the vertical rod 2251 to perform regular circular motion, and then the vertical rod 2251 is used to drive the clamping exhaust mechanism 180 to move, drive the separator to move, and perform exhaust and auxiliary desilting operations.

[0045] See also Figure 4 The independent driver 226 includes an electromagnetic pin 2261 and a bayonet pin 2262 . The bayonet pin 2262 is fixedly connected to the outer periphery of the rotating rod 222 , and the electromagnetic pin 2261 is slidably connected to the inner walls of the driving worm 223 and the heating worm 224 .

[0046] In the initial state, the electromagnetic pin 2261 is completely in the internal groove of the driving worm 223. When the worm wheel 225 corresponding to a certain separator needs to rotate, the electromagnetic pin 2261 is started, protrudes to the outside of the driving worm 223, contacts the bayonet pin 2262 set on the rotating rod 222 and is driven to rotate by the bayonet pin 2262. It should be noted that the contact between the bayonet pin 2262 and the inner wall of the driving screw is a low-friction contact.

[0047] See also Figure 5 as well as Figure 6, the heating component 227 includes a heating wire and an opening / closing cover 2271. The heating wire is disposed inside the heating worm 224. The opening / closing cover 2271 is rotatably connected to the outer wall of the body 210, and the opening / closing cover 2271 is a two-piece structure that is snap-connected to each other; wire passing holes 2272 are provided in both the upper and lower parts of the opening / closing cover 2271; a wire clamping buckle is provided in the middle screw groove of the heating worm 224.

[0048] After completing the pre-rinsing step, open the opening / closing cover 2271, fasten the blood return pipeline 160 to the screw groove in the middle of the heating screw through the wire clamping buckle, then close the opening / closing cover 2271, start the motor 221 to drive the rotating rod 222 to rotate, and then drive the heating screw to rotate, wind the upper and lower ends of the blood return pipeline 160 around the screw groove of the heating screw, and use the heating wire to heat it during the treatment process. The spiral continuous heating improves the heating efficiency and uniformity of the blood.

[0049] As another embodiment, as Figure 3 and Figures 7 to 11 shown, the clamping and exhaust mechanism 180 includes an outer clamping plate 181, an inner clamping plate 182, a plurality of groups of springs 183, a hoop 184, a swinging assembly 185, and a rotating and vibrating assembly 186; both the outer clamping plate 181 and the inner clamping plate 182 are open arc-shaped structures. The lower side wall of the inner clamping plate 182 is rotatably connected to the outer clamping plate 181. The outer wall of the inner clamping plate 182 is connected to the inner wall of the outer clamping plate 181 through a spring 183. One end of the hoop 184 is rotatably connected to the opening of the inner clamping plate 182, and the other end of the hoop 184 is snap-connected to the inner clamping plate 182. Cushions 187 are provided on the inner sides of both the inner clamping plate 182 and the hoop 184.

[0050] Among them, the snap connection between the hoop 184 and the inner clamping plate 182 is a design that can be opened, so that the separator can be effectively clamped by tightening the hoop 184 and cooperating with the inner clamping plate 182. At the same time, the rotational connection between the inner clamping plate 182 and the outer clamping plate 181 has a certain gap, so that the inner clamping plate 182 can vibrate effectively.

[0051] When performing the treatment preparation work, open the hoop 184, insert the separator into the inner clamping plate 182, and then tighten the hoop 184, so that the separator is clamped under the pressure of the cushion 187, and then the installation and connection of the pipeline 160 can be carried out.

[0052] See Figures 7 to 11, the swinging mechanism includes a rotating column 1851, an arc-shaped chute 1852, a slider 1853, a limiting track 1854, and a first connecting rod 1855; one end of the rotating column 1851 is fixedly connected to the rear end of the outer clamping plate 181, the rotating column 1851 is rotatably connected to the inner wall of the machine body 210, the arc-shaped chute 1852 is formed on the outer wall of the rotating column 1851, and the lower end of the slider 1853 is slidably connected to the rotating column 1851 through the arc-shaped chute 1852; the upper end of the slider 1853 is slidably connected to the limiting track 1854, the limiting track 1854 is fixedly connected to the inner wall of the machine body 210, the upper end of the slider 1853 is simultaneously rotatably connected to the first connecting rod 1855, and the end of the first connecting rod 1855 away from the slider 1853 is rotatably connected to the upper end of the vertical rod 2251.

[0053] Among them, the stroke angle of the arc-shaped chute 1852 is less than 90° to avoid excessive shaking and collision of parts; when performing pre-rinsing or dredging operations, the worm gear 225 rotates to drive the vertical rod 2251 to perform a circular motion, and then drives the slider 1853 to perform a reciprocating motion in the horizontal direction along the limiting slide rail through the first connecting rod 1855, so that the rotating column 1851 slidably connected to the slider 1853 moves. The rotating column 1851 is limited by the arc-shaped chute 1852 and can only perform a reciprocating swing with a maximum angle less than 90°, driving the outer clamping plate 181 to swing synchronously, and then driving the inner clamping plate 182 and the separator to swing synchronously.

[0054] See Figures 7 to 11 , the rotary vibration assembly 186 includes a rotating disk 1861, a toothless gear 1862, a rotating tooth 1863, and a second connecting rod 1864; the upper end of the rotating disk 1861 is fixedly connected to the lower end of the inner clamping plate 182, the rear end of the rotating tooth 1863 is rotatably connected to the side circumference of the rotating disk 1861, the lower end of the toothless gear 1862 is rotatably connected to the internal structure of the machine body 210, the teeth of the toothless gear 1862 are in contact with the rotating tooth 1863, one end of the second connecting rod 1864 is rotatably connected to the upper part of the toothless gear 1862, and the other end of the second connecting rod 1864 is rotatably connected to the lower part of the vertical rod 2251.

[0055] Among them, the rotational connection between the rotating tooth 1863 and the rotating disk 1861 has a certain damping to prevent the rotating tooth 1863 from rotating excessively, and several groups of rotating teeth 1863 are provided; the transmission between the toothless gear 1862 and the rotating tooth 1863 has a certain additional chamber.

[0056] When performing pre-rinsing or dredging operations, the worm rotates to drive the vertical rod 2251 to perform circular motion. The rotation of the second connecting rod 1864 drives the toothless gear 1862 to rotate synchronously. The toothless gear 1862 drives the rotating disk 1861 to rotate by driving the rotating tooth 1863, thereby driving the inner clamping plate 182 to rotate relative to the outer clamping plate 181, driving the separator to rotate, and at the same time stretching the spring 183 to store energy. When the toothless part of the toothless gear 1862 faces the rotating tooth 1863, the rotating tooth 1863 disengages from the transmission relationship with the toothless gear 1862, and the potential energy of the spring 183 is released to drive the inner clamping plate 182 and the separator to rotate rapidly in the reverse direction and generate vibration. This movement process can be carried out during the swinging process of the inner clamping plate 182. The deflected rotating tooth 1863 rotates correspondingly under the drive of the toothless gear 1862 to adapt to the tooth angle of the toothless gear 1862. At the same time, the thickness of the toothless gear 1862 is greater than the up and down displacement amplitude of the rotating disk 1861. The separator completes exhaust and dredging during rapid swinging, rotation, and vibration.

[0057] Working principle: When preparing for treatment, the first plasma separator 110, the second plasma separator 120, the first plasma component separator 130, and the second plasma component separator 140 are inserted into the corresponding inner clamping plates 182 in sequence and fixed by the hoop 184. Subsequently, the pipeline 160 is installed. After the installation of the pipeline 160 is completed, the pre-rinsing program is started. The rinsing liquid passes through the first plasma separator 110 and the first plasma component separator 130 and finally enters the waste liquid bag 190. At the same time, the motor 221 is started to drive the clamping and exhaust mechanism 180 to move. The slider 1853 reciprocates driven by the worm gear 225 and the vertical rod 2251, so that the rotating column 1851 drives the outer clamping plate 181 to swing reciprocally. At the same time, the toothless gear 1862 drives the rotating disk 1861 to rotate, thereby driving the inner clamping plate 182 to rotate, making the spring 183 store and release energy, so that the separator swings, rotates, and vibrates simultaneously to discharge the internal gas.

[0058] When the separator becomes blocked during the treatment process, the motor 221 is started to control the standby separator to perform the exhaust operation. Subsequently, the flow control valve 161 switches the pipeline 160 so that the blood enters the separator that has completed the exhaust operation, while the blocked separator is flushed and dredged in cooperation with the movement of the clamping and exhaust mechanism 180. After the dredging is completed, it is put on standby. If the separator becomes blocked again, the blood passage is switched to the separator that has completed the dredging, and the blocked separator is automatically dredged, thereby ensuring that the treatment process will not be interrupted.

[0059] When connecting the pipeline 160, by opening the opening and closing cover 2271, the reflux pipeline 160 is clamped in the screw groove in the middle of the heating screw through the wire clamping buckle. Subsequently, the motor 221 is started to drive the heating screw to rotate, and the pipelines 160 on the upper and lower sides of the heating screw are rotated and wound in the screw groove of the heating screw for blood heating.

[0060] The above is only the preferred embodiment of the present invention, and does not impose any formal restrictions on the present invention. Any person skilled in the art can make many possible changes and modifications to the technical solution of the present invention by using the above technical content without departing from the scope of the technical solution of the present invention, or modify it into an equivalent embodiment with equivalent changes. Therefore, all changes, modifications, equivalent changes and modifications made to the above embodiments based on the technical solution of the present invention without departing from the content of the technical solution of the present invention belong to the protection scope of this technical solution.

Claims

1. A double plasma exchange system, characterized in that , comprising a first plasma separator (110), a second plasma separator (120), a first plasma component separator (130), a second plasma component separator (140), two groups of flushing liquid bags (150) and an array of pipelines (160); the two groups of flushing liquid bags (150) are respectively connected to the first plasma separator (110), the second plasma separator (120), the first plasma component separator (130) and the second plasma component separator (140) through the pipeline (160); the pipeline (160) The liquid flow rate is controlled by a pump body (170), and a diverter valve (161) is provided in the pipeline (160); all separators are clamped by a clamping and exhausting mechanism (180), and the clamping and exhausting mechanism (180) discharges bubbles in the separators by shaking, rotating and vibrating; and assists the flushing liquid in clearing the silt; the first plasma separator (110) and the first plasma component separator (130) separate the toxins in the patient's blood, and then add the supplementary fluid to return the purified blood to the patient's body through the pipeline (160).

2. The dual plasma exchange system according to claim 1, characterized in that: It also includes a waste liquid bag (190) and a replenishing liquid bag (200), wherein the waste liquid bag (190) is connected to the first plasma separator (110), the second plasma separator (120), the first plasma component separator (130), and the second plasma component separator (140) respectively through the pipeline (160); and the replenishing liquid bag (200) is connected to the reflux point of the pipeline (160).

3. The dual plasma exchange system according to claim 1, characterized in that: It also comprises a machine body (210), the clamping exhaust mechanism (180) is fixedly connected to the machine body (210), a bottle hanging rack (211) is arranged at the upper end of the machine body (210), the pump body (170) is fixedly connected to the machine body (210), and the pipeline (160) is detachably connected to the machine body (210).

4. The dual plasma exchange system according to claim 3, characterized in that: An automatic control system (212) is disposed on the upper side of the machine body (210), and the automatic control system (212) directly controls the operation of the pump body (170) and the diverter valve (161). A driving mechanism (220) is also disposed inside the machine body (210), and the driving mechanism (220) is transmission-connected to the clamping and exhausting mechanism (180).

5. The dual plasma exchange system according to claim 4, characterized in that: The driving mechanism (220) comprises a motor (221), a rotating rod (222), four sets of driving worms (223), a heating worm (224), four sets of worm wheels (225), an independent driver (226) and a heating component (227); the rear end of the motor (221) is bolted to the inner wall of the machine body (210), the output end of the motor (221) is plugged into the rotating rod (222), the side of the rotating rod (222) away from the motor (221) passes through the machine body (210) and is rotatably connected to the machine body (210); the driving worm (223) and the heating worm (224) are connected to the machine body (210) by a screw. The heating worm (224) is sleeved on the outer periphery of the rotating rod (222) and is rotationally connected with the rotating rod (222) with a limited position to prevent the driving worm (223) from horizontal displacement. The heating worm (224) is positioned at the portion of the rotating rod (222) located outside the machine body (210). The independent driver (226) is fixedly connected to the outer periphery of the rotating rod (222). The worm wheel (225) is transmission-connected to the driving worm (223). The worm wheel (225) is rotationally connected to the inside of the machine body (210). A vertical rod (2251) is fixedly provided on the upper end of the worm wheel (225).

6. The dual plasma exchange system according to claim 5, characterized in that: The independent driver (226) comprises an electromagnetic pin (2261) and a bayonet pin (2262), wherein the bayonet pin (2262) is fixedly connected to the outer periphery of the rotating rod (222), and the electromagnetic pin (2261) is slidably connected to the inner walls of the driving worm (223) and the heating worm (224).

7. The dual plasma exchange system according to claim 5, characterized in that: The heating component (227) includes a heating wire and an opening and closing cover body (2271), wherein the heating wire is arranged inside the heating worm (224), the opening and closing cover body (2271) is rotatably connected to the outer wall of the body (210), and the opening and closing cover body (2271) is a two-section mutually clamped structure; wiring holes (2272) are provided at the upper and lower parts of the opening and closing cover body (2271); and a wire buckle is provided in the middle screw groove of the heating worm (224).

8. The dual plasma exchange system according to claim 5, characterized in that: The clamping exhaust mechanism (180) comprises an outer clamping plate (181), an inner clamping plate (182), an array of springs (183), a clamping hoop (184), a swinging assembly (185) and a rotating vibration assembly (186); the outer clamping plate (181) and the inner clamping plate (182) are both open arc structures, the lower end side wall of the inner clamping plate (182) is rotatably connected to the outer clamping plate (181), the outer wall of the inner clamping plate (182) and the inner wall of the outer clamping plate (181) are connected through the spring (183), one end of the clamping hoop (184) is rotatably connected to the opening of the inner clamping plate (182), and the other end of the clamping hoop (184) is snap-connected to the inner clamping plate (182), and a cushion layer (187) is provided on the inner side of the inner clamping plate (182) and the clamping hoop (184).

9. The dual plasma exchange system according to claim 8, characterized in that: The swing mechanism comprises a rotating column (1851), an arc-shaped slide groove (1852), a slider (1853), a limiting track (1854) and a first connecting rod (1855); one end of the rotating column (1851) is fixedly connected to the rear end of the outer clamping plate (181); the rotating column (1851) is rotatably connected to the inner wall of the body (210); the arc-shaped slide groove (1852) is provided on the outer wall of the rotating column (1851); the lower end of the slider (1853) is fixedly connected to the outer clamping plate (181); The arc-shaped slide groove (1852) is slidably connected to the rotating column (1851); the upper end of the slider (1853) is slidably connected to the limiting track (1854), and the limiting track (1854) is fixedly connected to the inner wall of the body (210); the upper end of the slider (1853) is rotatably connected to the first connecting rod (1855), and the end of the first connecting rod (1855) away from the slider (1853) is rotatably connected to the upper end of the vertical rod (2251).

10. The dual plasma exchange system according to claim 9, characterized in that: The rotary vibration component (186) comprises a rotating disk (1861), a toothless gear (1862), rotating teeth (1863) and a second connecting rod (1864); the upper end of the rotating disk (1861) is fixedly connected to the lower end of the inner clamping plate (182), the rear end of the rotating teeth (1863) is rotationally connected to the side of the rotating disk (1861), the lower end of the toothless gear (1862) is rotationally connected to the internal structure of the body (210), the teeth of the toothless gear (1862) are in contact with the rotating teeth (1863), one end of the second connecting rod (1864) is rotationally connected to the upper part of the toothless gear (1862), and the other end of the second connecting rod (1864) is rotationally connected to the lower part of the vertical rod (2251).

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