Electronic vomit stopping instrument and system based on electrical stimulation

Abstract

The invention discloses an electronic vomit stopping instrument and system based on electrical stimulation, and relates to the technical field of electrotherapy vomit stopping. The electronic vomit-stopping instrument comprises an electrode part which is used for being in contact with an acupoint with a vomit-stopping effect on a body part of a patient and applying non-invasive electrical stimulation; the current pulse generating part is electrically connected with the electrode part and is used for generating controllable current pulses and transmitting the controllable current pulses to the electrode part; the electrical stimulation control module is electrically connected with the current pulse generation part and is used for controlling the current pulse generation part to work; wherein the control part is configured to receive an electrical stimulation instruction, control the current pulse generation part to enter a working state at intervals according to interval time and current pulse parameters configured in the electrical stimulation instruction and the interval time, and generate current pulses according to the current pulse parameters. Through an interval electrical stimulation mode, the time for the patient to have tolerance can be prolonged, and manual adjustment is reduced.

Description

Technical Field

[0001] The present invention relates to the technical field of electrotherapy for antiemesis, and in particular to an electronic antiemetic device and system based on electrical stimulation. Background Art

[0002] Cancer patients often experience side effects such as nausea and vomiting to varying degrees after chemotherapy. Nausea and vomiting often lead to abnormal diet and dehydration in patients, and cause patients to have a fear of chemotherapy, seriously affecting the quality of life of patients and the compliance of treatment. Clinically, drug intervention is mostly used for vomiting. The antiemetic drugs currently used clinically mainly include anti-parasympathetic drugs, antihistamines, dopamine receptor blockers (such as phenothiazine, phenylbutanone, benzamide), 5-hydroxytryptamine receptor antagonists, and neurokinin-1 receptor antagonists such as aprepitant. However, there are many problems in the actual application of the above antiemetic drugs, such as large side effects, difficult to control the action time, etc., and some patients will develop drug resistance to antiemetic drugs. As the drug use time prolongs, the drug efficacy will weaken.

[0003] Based on the above problems, the prior art provides other treatment means that can be used for chemotherapy-induced antiemesis. For example, Chinese Patent Application CN201410406445.X discloses a package for antiemetic drugs and non-invasive electrical stimulation, including: a first packaging unit containing antiemetic drugs and a second packaging unit containing non-invasive electrical stimulation, with independent packaging spaces; the first packaging unit containing antiemetic drugs includes tropisetron in a clinically effective dose, and the second packaging unit containing non-invasive electrical stimulation includes non-invasive electrical stimulation that reaches the acupoints by outputting a weak current. The above solution prevents and treats nausea and vomiting in TACE patients through the combination of the antiemetic drug tropisetron and non-invasive electrical stimulation. The test results show that the overall effective rate of antiemetic treatment using acupoint (Neiguan acupoint, Gongsun acupoint, Hegu acupoint) electrical stimulation combined with tropisetron is better than that of the simple tropisetron antiemetic group. The antiemetic effect of the combined group in the acute phase after TACE is better than that of the simple antiemetic drug group. The incidence of acute and delayed vomiting in patients with the combined intervention measure is significantly lower than that of those who only take antiemetic drugs without receiving electrical stimulation intervention. The postoperative appetite recovery and bowel movement status are good, which is beneficial to improving the quality of life. Another example is that Chinese Patent Application CN201910963622.7 discloses a low-frequency pulse antiemetic device with time control, including an MCU control for generating PWM signals to calculate and control the instructions of each component module of the electronic antiemetic device; a pulse generation system for generating low-frequency pulse signals to stimulate the higher center of the cerebral cortex to stop vomiting; a physical button control for controlling the power on / off and pulse signal intensity adjustment of the electronic antiemetic device; a liquid crystal scanning display system for displaying the working status of the electronic antiemetic device; a power supply system for supplying power to each module of the electronic antiemetic device; and a USB charging interface for charging the electronic antiemetic device through the USB interface; the USB charging interface is connected to the power supply system, and also includes a duration control card system for the MCU control to control the low-frequency pulse output duration of the pulse generation system by reading the data in the duration control card system. The above prior art solutions utilize traditional Chinese medicine acupoint knowledge to relieve or treat the nausea and vomiting symptoms of chemotherapy patients by applying non-invasive electrical stimulation to the acupoints with antiemetic effects. For example, the Neiguan acupoint on the wrist, by stimulating the meridian on the inner wrist, is transmitted upward to the vomiting center, affecting the nerve signal conduction of the vagus nerve and the vomiting center, and reducing vomiting and nausea symptoms. At the same time, the benign stimulation can stimulate the integration and adjustment functions of the higher nerve center, produce a series of neurohumoral regulations, and mobilize the body's potential disease resistance ability.

[0004] At present, when stimulating acupoints through non-invasive electrode patches, a single-acupoint dual-electrode structure is usually adopted for electrical stimulation - that is, two electrodes (including a positive electrode and a negative electrode) are electrically connected to a single acupoint, and the current forms a closed loop locally. During stimulation, the current flows along the shortest path between the two electrodes, and the stimulation range is controllable. The single-acupoint dual-electrode structure has the advantages of clear current path, high safety, strong anti-interference ability, etc., and the electrical stimulation range can be adjusted by the electrode spacing. However, in the actual chemotherapy antiemetic treatment process, it is found that the existing electrical stimulation scheme is usually regular continuous electrical stimulation, and patients are prone to develop tolerance, that is, the perceived electroacupuncture stimulation intensity by patients will gradually decrease over time, and the electrical treatment effect will weaken. The traditional solution is limited by the maximum current intensity that the patient can bear, and the intensity is adjusted in a timely manner according to the patient's feelings during the treatment. The above scheme requires medical staff to timely ask about the patient's feelings and adjust the current stimulation intensity according to the patient's feelings, which greatly increases the workload of medical staff. Accordingly, the existing technology has also proposed improvements. It sets electrical pulse intensity adjustment gears on the electronic antiemetic device - such as an electrical pulse output increase key button and a decrease key button for the patient to adjust to reduce the workload of medical staff, but there is still the problem of patient stimulation tolerance; moreover, during the treatment process, manual adjustment of the instrument is still required. When the patient cannot operate manually (such as an elderly person who has difficulty remembering the operation method of the instrument) or cannot adjust manually (such as when the patient is very uncomfortable and has difficulty operating the instrument automatically), medical staff or relevant personnel still need to give assistance beside the instrument. Summary of the Invention

[0005] The purpose of the present invention is to: overcome the deficiencies of the prior art and provide an electronic antiemetic device and system based on electrical stimulation. The electronic antiemetic device provided by the present invention includes an intermittent electrical stimulation mode. After receiving an electrical stimulation instruction, the electrical stimulation control module can, according to the interval time and current pulse parameters configured in the electrical stimulation instruction, control the current pulse generation unit to intermittently enter the working state at the interval time and generate current pulses according to the aforementioned current pulse parameters. Compared with the existing regular continuous electrical stimulation, the intermittent electrical stimulation mode can extend the time for patients to develop tolerance and reduce manual adjustment. Further, it can also adjust the current pulse parameters and electrode spacing as the electrical treatment progresses.

[0006] To achieve the above objectives, the present invention provides the following technical solutions: An electronic antiemetic device based on electrical stimulation, comprising: An electrode part for contacting an acupoint with antiemetic effect on the patient's body part and applying non-invasive electrical stimulation; A current pulse generation part electrically connected to the electrode part for generating controllable current pulses and transmitting them to the aforementioned electrode part; The electrical stimulation control module is electrically connected to the current pulse generation unit and is used to control the operation of the current pulse generation unit. Among them, the electrical stimulation control module is configured to: receive an electrical stimulation instruction, and according to the interval time and current pulse parameters configured in the electrical stimulation instruction, control the current pulse generation unit to enter the working state intermittently at the interval time, and generate current pulses according to the foregoing current pulse parameters.

[0007] Furthermore, it includes a user interaction unit for collecting the selected electrical stimulation mode and current pulse parameters by the user. The electrical stimulation mode includes a continuous electrical stimulation mode and an intermittent electrical stimulation mode, which respectively correspond to different electrical stimulation instructions. The current pulse parameters include the current pulse output duration and the current pulse output intensity information. For the intermittent electrical stimulation mode, the current pulse output duration of the current pulse parameters includes the total working duration, the number of working cycles, and the working duration of each working cycle.

[0008] Furthermore, the electrode unit includes two electrode structures for contacting the patient's skin. The first electrode structure is the positive electrode, and the second electrode structure is the negative electrode. The electrode structure is an artificial plant root structure, including a main electrode in the middle and peripheral root electrodes located outside the main electrode. Electrode driving motors are provided corresponding to the main electrode and the peripheral root electrodes for driving the electrode heads of the corresponding electrodes to expand and contract. The electrode driving motors are connected to the electrical stimulation control module and receive the control of the electrical stimulation control module. The electrical stimulation control module is configured to: when the working time of the current pulse generation unit arrives, control the electrode driving motors so that one electrode head of each of the first electrode structure and the second electrode structure contacts the skin as the working electrode, respectively forming the positive electrode and the negative electrode of the current loop; and during the application of electrical stimulation, control the electrode driving motors to drive the electrode heads on the first electrode structure and the second electrode structure to contact or move away from the skin to adjust the working electrode, and adjust the electrode spacing for applying electrical stimulation by adjusting the working electrode.

[0009] Furthermore, a working electrode dynamic adjustment control instruction is preset. The working electrode dynamic adjustment control instruction is configured to: in the initial state, use the main electrodes of the first electrode structure and the second electrode structure as the working electrodes. When the preset electrode adjustment cycle arrives, adjust the working electrode of the first electrode structure to one of the peripheral root electrodes, and keep the working electrode of the second electrode structure as the main electrode, waiting for the next electrode adjustment cycle to arrive; when the next electrode adjustment cycle arrives, restore the working electrode of the first electrode structure to the main electrode, and adjust the working electrode of the second electrode structure to one of the peripheral root electrodes. When the electrode adjustment cycle ends, end the working electrode adjustment and restore to the foregoing initial state. The electrical stimulation control module is configured to: when the current pulse generation unit is operating, execute the working electrode dynamic adjustment control instruction at least once; wherein, for the intermittent electrical stimulation mode, the working electrode dynamic adjustment control instruction is executed at least once in each working cycle.

[0010] Furthermore, the electrical stimulation control module is further configured to: differentially set the current pulse intensities of the main electrode and the peripheral root electrodes as working electrodes, the current pulse intensity when the main electrode is used as the working electrode being higher than that when the peripheral root electrode is used as the working electrode; and, When there are multiple peripheral root electrodes outside the main electrode, the current pulse intensity of the root electrode closer to the outside as the working electrode is higher than that of the root electrode closer to the inside as the working electrode.

[0011] Furthermore, it further includes a patient state recognition module, which is communicatively connected to the electrical stimulation control module and is configured to: collect the physical state data of the patient during the electrical stimulation treatment, determine whether to continue applying electrical stimulation based on the physical state data, and when it is determined not to apply electrical stimulation, send an end electrical stimulation instruction to the electrical stimulation control module; When receiving the aforementioned end electrical stimulation instruction, the electrical stimulation control module controls the current pulse generation unit to enter the standby state.

[0012] The present invention also provides a chemotherapy antiemetic treatment system, which includes: A body support device for allowing the patient to sit or lie in a preset body posture; An antiemetic treatment device, including the aforementioned electronic antiemetic instrument, and performing electrical stimulation treatment on one or more target acupoints on one or more body parts of the patient through the electrode part of the electronic antiemetic instrument.

[0013] Furthermore, the antiemetic treatment device further includes a massage unit, and the massage unit at least includes a central area and a peripheral area surrounding the central area; A first massage structure is provided in the central area, and the electrode part of the electronic antiemetic instrument is provided on the massage head of the first massage structure for performing electrical stimulation on the position of the target acupoint; A second massage structure is provided in the peripheral area for massaging and stimulating the target acupoint around the position of the target acupoint from the outside to the inside or from the inside to the outside around the acupoint.

[0014] Furthermore, the massage head of the first massage structure is a multi-layer nested structure, including an inner layer, a first rotating layer sleeved outside the inner layer, and a second rotating layer sleeved outside the first rotating layer. The electrode part is provided on the surface of the inner layer, the inner layer can be telescopically adjusted relative to the first rotating layer, and the first rotating layer can be telescopically adjusted relative to the second rotating layer; The antiemetic treatment device is configured to: collect size information of a body part of a patient, determine the patient type according to the size information of the body part, and then adjust the telescopic states of each layer of the massage head according to the patient type to adjust the contact area between the massage head and the patient's skin; wherein, when the patient is of the child type, the inner layer and the first rotating layer are in the extended state and in contact with the patient's skin, electrical stimulation is performed through the inner layer, and skin massage is performed by rotating the first rotating layer; when the patient is of the general user type, the inner layer and the first rotating layer are in the retracted state, electrical stimulation is performed through the inner layer, and skin massage is performed by rotating the first rotating layer and the second rotating layer.

[0015] Further, the massage stimulation is contraction and expansion massage, the second massage structure includes a massage head for realizing the contraction and expansion functions, and a liquid outlet hole is provided on the massage head; It further includes a liquid delivery module, which includes a liquid delivery path provided corresponding to the massage head, and the output end of the liquid delivery path is connected to the liquid outlet hole on the massage head: the liquid delivery module is configured to: when receiving a liquid outlet instruction sent by the antiemetic treatment device, according to the massage head information in the liquid outlet instruction, control the liquid delivery path to communicate with the liquid outlet hole of the corresponding massage head, and then deliver liquid to the corresponding massage head.

[0016] Due to the adoption of the above technical solutions, compared with the prior art, for example, the present invention has the following advantages and positive effects: the electronic antiemetic instrument based on electrical stimulation includes an intermittent electrical stimulation method. After receiving an electrical stimulation instruction, the electrical stimulation control module can, according to the intermittent time and current pulse parameters configured in the electrical stimulation instruction, control the current pulse generation unit to enter the working state intermittently at the intermittent time, and generate current pulses according to the aforementioned current pulse parameters. Compared with the existing regular continuous electrical stimulation, the intermittent electrical stimulation mode can extend the time for patients to develop tolerance and reduce manual adjustment. Further, it can also adjust the current pulse parameters during the electrical treatment.

[0017] Further, the electrode structure is an imitation plant root structure: including a main electrode in the middle and peripheral root electrodes located outside the main electrode; during electrical treatment, it is possible to control the peripheral root electrodes to contact or move away from the skin to dynamically adjust the electrode spacing for applying electrical stimulation, and the dynamic electrode spacing can form a dynamic current stimulation range.

[0018] Further, the present invention combines electrical stimulation treatment with acupoint massage. While applying electrical stimulation to acupoints, massage stimulation is applied through the massage unit to enhance the stimulation effect and further relieve or treat the vomiting symptoms of tumor chemotherapy patients. Specifically, the massage unit for performing acupoint massage is also improved, and it can perform different types of stimulation on the acupoint area and the area around the acupoint. Description of the Drawings

[0019] Figure 1 The module structure of the electronic antiemetic device based on electrical stimulation provided by the embodiments of the present invention Figure 1 。

[0020] Figure 2 The module structure of the electronic antiemetic device based on electrical stimulation provided by the embodiments of the present invention Figure 2 。

[0021] Figure 3 Schematic diagram of the electrode structure of the plant root-like structure provided by the embodiments of the present invention

[0022] Figure 4 Schematic diagram of the electrode spacing between the positive and negative electrodes provided by the embodiments of the present invention

[0023] Figure 5 Schematic diagram of the change in the electrode spacing between the positive and negative electrodes during the adjustment of the working electrode provided by the embodiments of the present invention

[0024] Figure 6 Schematic diagram of the module structure of the chemotherapy antiemetic treatment system provided by the embodiments of the present invention

[0025] Figure 7 Schematic diagram of the massage head structure including a central area and a peripheral area provided by the embodiments of the present invention

[0026] Figure 8 Schematic diagram of the massage head structure of the multi-layer nested structure provided by the embodiments of the present invention

[0027] Figure 9 Schematic diagram of the peripheral area structure including multiple massage rings provided by the embodiments of the present invention

[0028] Explanation of reference numerals: Electrode part 100, first electrode structure 110, second electrode structure 120, main electrodes 111, 121, peripheral root electrodes 112, 122; Massage unit 200, central area 210, peripheral area 220, inner layer 211, first rotating layer 212, second rotating layer 213, first massage ring sub-area 2201, first massage ring sub-area 2201, second massage structure 221. Detailed implementation manners

[0029] The following further elaborates in detail on the electronic anti-nausea device and system based on electrical stimulation disclosed in the present invention in conjunction with the accompanying drawings and specific embodiments. It should be noted that the technical features or combinations of technical features described in the following embodiments should not be considered in isolation, and they can be combined with each other to achieve better technical effects. In the accompanying drawings of the following embodiments, the same reference numerals appearing in each drawing represent the same features or components, which can be applied to different embodiments. Therefore, once a certain item is defined in one drawing, it does not need to be further discussed in the subsequent drawings.

[0030] It should be noted that the structures, ratios, sizes, etc. shown in the drawings of this specification are only used to cooperate with the content disclosed in the specification for those skilled in this technology to understand and read, and are not used to limit the limiting conditions for the implementation of the invention. Any modification of the structure, change in the proportional relationship, or adjustment of the size, without affecting the efficacy that the invention can produce and the purpose that can be achieved, should fall within the scope covered by the technical content disclosed in the invention. The scope of the preferred implementation mode of the present invention includes additional implementations, where the functions can be executed in a substantially simultaneous manner or in the reverse order according to the functions involved, rather than in the order described or discussed. This should be understood by those skilled in the technical field of the embodiments of the present invention.

[0031] For technologies, methods, and devices known to those of ordinary skill in the relevant fields, they may not be discussed in detail, but under appropriate circumstances, the said technologies, methods, and devices should be regarded as a part of the authorized specification. In all the examples shown and discussed here, any specific value should be interpreted as merely exemplary and not as a limitation. Therefore, other examples of the exemplary embodiments can have different values.

[0032] In the description of the embodiments of the present application, " / " means "or", and "and / or" is used to describe the association relationship of associated objects, indicating that three relationships can exist. For example, "A and / or B" means: A exists alone, B exists alone, and both A and B exist simultaneously. In the description of the embodiments of the present application, "a plurality of" means two or more. Embodiment

[0033] See Figure 1 As shown, an electronic anti-nausea device based on electrical stimulation provided by the present invention is presented. The electronic anti-nausea device includes an electrode part, a current pulse generation part, and an electrical stimulation control module.

[0034] The electrode part is used to contact acupoints on the patient's body part with anti-nausea effects and apply non-invasive electrical stimulation. Specifically, the electrode part includes two electrode structures for contacting the patient's skin, with the first electrode structure being the positive electrode and the second electrode structure being the negative electrode.

[0035] The current pulse generating unit is electrically connected to the electrode unit and is used to generate controllable current pulses and transmit them to the aforementioned electrode unit. Specifically, the current pulse generating unit can generate periodic low-frequency bidirectional pulse waves to stimulate acupoint nerves - for example, stimulating the nerves of the Neiguan acupoint and transmitting them upward to the vomiting center, so as to regulate the signals leading to neurogenic vomiting and the signals of the vagus nerve traveling back and forth to the stomach, and achieve the purpose of alleviating vomiting, nausea, and anorexia symptoms. The current pulse generating unit can use existing low-frequency electronic pulse instruments, which will not be elaborated here.

[0036] The electrical stimulation control module is electrically connected to the current pulse generating unit and is used to control the operation of the current pulse generating unit.

[0037] Among them, the electrical stimulation control module is configured to: receive an electrical stimulation instruction, and according to the interval time and current pulse parameters configured in the electrical stimulation instruction, control the current pulse generating unit to enter the working state intermittently at the interval time, and generate current pulses according to the aforementioned current pulse parameters.

[0038] See Figure 2 As shown, the electronic anti-vomiting device may further include a user interaction unit for information interaction with the user. Specifically, the user interaction unit can collect the selected electrical stimulation mode and current pulse parameters of the user.

[0039] The electrical stimulation mode includes a continuous electrical stimulation mode and an intermittent electrical stimulation mode, which respectively correspond to different electrical stimulation instructions. For the continuous electrical stimulation mode, the corresponding interval time is configured to 0; for the intermittent electrical stimulation mode, the corresponding interval time can be any non-zero value. Specifically, the interval time can be set by the system default or personalized by the user.

[0040] The current pulse parameters at least include the current pulse output duration (s) and the current pulse output intensity (mA) information. For the intermittent electrical stimulation mode, the current pulse output duration of the current pulse parameters may include the total working duration, the number of working cycles, and the working duration of each working cycle.

[0041] In specific implementation, the user interaction unit may include a first physical button or knob for electrical stimulation mode selection, and a second physical button or knob for rotating the current pulse parameters. The user can configure the electrical stimulation mode and current pulse parameters for the patient's electrical stimulation treatment through the physical button or knob. Alternatively, the user interaction unit includes a user graphical interaction interface (GUI), and the selected electrical stimulation mode and current pulse parameter information are obtained through the stimulation parameter collection column on the GUI interface.

[0042] In this embodiment, the interval time between the multiple working cycles can be the same or different. In a preferred embodiment, as the electrostimulation treatment progresses, the interval time can be shortened according to a preset rule, and the working duration of the working cycle can be increased according to a preset rule. Further, as the electrostimulation treatment progresses, the output intensity of the current pulse can also be adjusted. For example, in the intermittent electrostimulation mode, for multiple working cycles, the output intensity of the current pulse in the subsequent working cycle can be increased by a preset intensity ΔI (mA) compared to the current pulse intensity in the previous working cycle.

[0043] At this time, the current pulse parameters further include the initial value I0 of the output intensity of the current pulse and the change value ΔI of the current pulse intensity, which can be configured and selected by the user. Since the applied output intensity of the current pulse needs to be within the preset safety value of the current pulse intensity, after the user configures the number of working cycles, the initial value I0 of the output intensity of the current pulse, and the change value ΔI of the current pulse intensity, the corresponding termination value of the output intensity of the current pulse (i.e., the output intensity of the current pulse in the last working cycle) can be calculated. When the calculated termination value of the output intensity of the current pulse is greater than the aforementioned safety value, the user is reminded to reconfigure the parameters to ensure that the termination value of the output intensity of the current pulse is less than the aforementioned safety value. The safety value can be the default value of the system or a personalized value set according to the patient.

[0044] In a preferred embodiment, the electrode structure is a structure imitating plant root hairs, including a main electrode in the middle and peripheral root hair electrodes located outside the main electrode.

[0045] See Figure 3 As shown, taking the first electrode structure 110 as an example, a typical manner of the electrode structure imitating plant root hairs is exemplified: the first electrode structure 110 includes a main electrode 111 in the middle and peripheral root hair electrodes 112 located outside the main electrode 111. A plurality of peripheral root hair electrodes 112 can extend downward from a certain position or multiple positions on the main electrode 111 to form a plurality of root hair electrode heads, and a main electrode head is also formed below the main electrode. The main electrode and the peripheral root hair electrodes are electrically connected, and the current pulse injected (or input) from the input end of the main electrode can be transmitted to the electrode heads of the respective electrodes below. The respective electrode heads are provided on the housing of the electrode part. As seen on the surface of the electrode part housing, a plurality of peripheral root hair electrode heads are arranged around the electrode head of the main electrode. See Figure 4 As shown. Preferably, the plurality of peripheral root hair electrode heads are arranged in a ring with the position of the main electrode head as the center, and each peripheral root hair electrode head is located at a different azimuth outside the main electrode head but at an equal distance from the center of the main electrode head.

[0046] It should be noted that although Figure 3 and Figure 4Only the method of arranging four root electrodes around a main electrode is exemplified. However, those skilled in the art should understand that the above arrangement method is for illustration rather than limitation. The number of the surrounding root electrodes can be set more or less according to needs, such as setting 1, 2, 3, 5, etc. At the same time, the distances and azimuth angles of the respective root electrodes relative to the main electrode can also be configured according to needs.

[0047] The second electrode structure 120 has the same structure as the first electrode 110, and will not be described in detail here.

[0048] In this embodiment, an electrode driving motor, such as a micro telescopic motor, is also provided corresponding to the main electrode and the surrounding root electrodes, for driving the electrode heads of the corresponding electrodes to perform telescopic movement. The electrode driving motor is connected to the electrical stimulation control module and receives the control of the electrical stimulation control module. The protruding electrode head can be flush with the surface of the electrode part housing or protrude relative to the surface of the electrode part housing to form a working electrode, while the retracted electrode head is received in the electrode part housing, such as in an inner concave groove of the housing, as a non-working electrode.

[0049] The electrical stimulation control module is configured to: when the working time of the current pulse generation unit arrives, control the electrode driving motor so that one electrode head of each of the first electrode structure and the second electrode structure contacts the skin as a working electrode, respectively forming the positive electrode and the negative electrode of the current loop; and, during the application of electrical stimulation, control the electrode driving motor to drive the electrode heads on the first electrode structure and the second electrode structure to contact or move away from the skin to adjust the working electrode, and adjust the electrode spacing of the applied electrical stimulation by adjusting the working electrode.

[0050] That is to say, during the operation of the current pulse generation unit, the dynamic adjustment of the working electrode can be realized by controlling the telescopic state of each electrode head through the electrical stimulation control module, and during this period, only one positive electrode and one negative electrode contact the skin to form a circuit loop (the other electrodes are retracted in the housing and are in a received state and will not contact the patient's skin).

[0051] Preferably, in this embodiment, a control instruction for dynamic adjustment of the working electrode can be preset. The control instruction for dynamic adjustment of the working electrode is configured as follows: in the initial state, the main electrodes of the first electrode structure and the second electrode structure are used as the working electrodes, and the corresponding electrode spacing is L0. See Figure 4As shown; when a preset electrode adjustment period arrives, the working electrode of the first electrode structure is adjusted to one of the peripheral root electrodes, and the working electrode of the second electrode structure keeps the main electrode unchanged and waits for the next electrode adjustment period to arrive; when the next electrode adjustment period arrives, the working electrode of the first electrode structure is restored to the main electrode, and the working electrode of the second electrode structure is adjusted to one of the peripheral root electrodes. When the electrode adjustment period ends, the adjustment of the working electrode ends and returns to the aforementioned initial state.

[0052] At this time, the electrical stimulation control module is configured to: when the current pulse generation unit is working, execute the working electrode dynamic adjustment control instruction at least once. Among them, for the intermittent electrical stimulation mode, the working electrode dynamic adjustment control instruction is executed at least once in each working cycle. At this time, the electrode adjustment period is configured according to the configured duration of the working cycle so that the working electrode dynamic adjustment control instruction can be completely executed at least once in each working cycle.

[0053] Among them, when there is one peripheral root electrode, the working electrode can be adjusted between the main electrode and this root electrode. When there are multiple peripheral root electrodes, the method of adjusting the working electrode to one of the peripheral root electrodes can be to select one as the working electrode from the peripheral root electrodes based on a preset root electrode selection rule.

[0054] Preferably, the root electrode selection rule is configured as follows: for each main electrode, after numbering the root electrodes around the main electrode, an initial root electrode list is constructed. In the initial root electrode list, the peripheral root electrodes are sorted in ascending order of the numbers; when it is necessary to adjust the working electrode from this main electrode to a peripheral root electrode, the peripheral root electrode ranked first in the root electrode list is selected as the current working electrode, and the number of the selected root electrode is moved from the first position of the root electrode list to the last position, and the numbers of the subsequent root electrodes are moved forward in turn to form an updated root electrode list; in the next adjustment (that is, when it is necessary to adjust the working electrode from this main electrode to a peripheral root electrode), based on the aforementioned updated root electrode list, the peripheral root electrode ranked first in the root electrode list is selected as the current working electrode, and the number of the selected root electrode is moved from the first position of the root electrode list to the last position, and the numbers of the subsequent root electrodes are moved forward in turn to form an updated root electrode list; and so on.

[0055] Figure 5The working electrode exemplifying the first electrode structure is the main electrode. When the working electrode of the second electrode structure is adjusted between the main electrode and the peripheral root electrode, the change in the electrode spacing of the electrical stimulation is involved. At this time, by way of example, the initial root electrode list corresponding to the main electrode of the second electrode structure can be [1, 2, 3, 4], and the numbers 1, 2, 3, and 4 respectively correspond to the peripheral root electrodes on the inner side, outer side, upper side, and lower side of the main electrode. In the initial state, when the main electrode of the second electrode structure is the working electrode, the corresponding electrode spacing is L0; when the working electrode of the second electrode structure needs to be adjusted, the root electrode corresponding to the first number in the aforementioned list (i.e., number 1) (i.e., the root electrode on the inner side of the main electrode) is selected as the working electrode. At this time, the corresponding electrode spacing is L1 < L0, and the updated root electrode list is [2, 3, 4, 1]. Subsequently, when the working electrode of the second electrode structure needs to be adjusted, the root electrode corresponding to the first number in the aforementioned updated list (i.e., number 2) (i.e., the root electrode on the outer side of the main electrode) is selected as the working electrode. At this time, the corresponding electrode spacing is L2 > L0, and the updated root electrode list is [3, 4, 1, 2]. And so on, when the root electrode on the upper side of the main electrode of the second electrode structure is the working electrode, the corresponding electrode spacing is L3 > L0, and the updated root electrode list is [4, 1, 2, 3]; when the root electrode on the lower side of the main electrode of the second electrode structure is the working electrode, the corresponding electrode spacing is L4 > L0, and the updated root electrode list is [1, 2, 3, 4]. In this way, each peripheral root electrode can be selected as the working electrode.

[0056] Through the above solution provided by the present invention, the dynamic adjustment of the electrode spacing is realized, thereby dynamically adjusting the current stimulation range. At the same time, the irregularity of the current stimulation is also increased, further prolonging the time for the patient to develop tolerance.

[0057] Preferably, the electrical stimulation control module can also be configured to: differentially set the current pulse intensities of the main electrode and the peripheral root electrode as the working electrode. Among them, the current pulse intensity when the main electrode is the working electrode can be higher than the current pulse intensity when the peripheral root electrode is the working electrode. If there are multiple peripheral root electrodes outside the main electrode, the current pulse intensity of the root electrode on the outer side as the working electrode can be higher than the current pulse intensity of the root electrode on the inner side as the working electrode.

[0058] In another implementation manner of this embodiment, a patient state recognition module can also be included, which is communicatively connected to the electrical stimulation control module.

[0059] Specifically, the patient status recognition module is configured to: collect the physical status data of the patient during electrostimulation therapy - for example, it can collect the physiological characteristic data, facial expression image data, and / or limb movement image data of the patient, etc., and determine whether to continue applying electrostimulation based on the physical status data - for example, when the collected data exceeds the preset standard value, and / or after image recognition of the facial expression or limb movement image data determines that the patient is uncomfortable, it can be determined that electrostimulation should not be continued at this time. At this time, an end electrostimulation instruction is sent to the electrostimulation control module.

[0060] When the electrostimulation control module receives the aforementioned end electrostimulation instruction, it controls the current pulse generation unit to enter the standby state. Optionally, the electronic antiemetic device can further include an alarm module. At this time, sound and / or light alarms are issued through the alarm module.

[0061] Preferably, when the time in the standby state exceeds the preset time, the current pulse generation unit can enter the shutdown state from the standby state.

[0062] In this embodiment, further, the electronic antiemetic device can further include other functional modules such as a power supply module, a power management module, and a display module. The power supply module is used to supply power to the electrical components of the electronic antiemetic device. The power management module can include a voltage stabilization circuit, a charging circuit, and a protection circuit; the voltage stabilization circuit is used to achieve voltage stabilization and constant current control; the charging circuit is used for charging management to prevent overcharging; the protection circuit is used for overcurrent, overvoltage, and short-circuit protection to ensure the safety of the stimulation output. The display module can include an indicator light and a screen to display information such as the working status of the antiemetic device and the electrostimulation process.

[0063] Another embodiment of the present invention also provides a chemotherapy antiemetic treatment system. The chemotherapy antiemetic treatment system at least includes a body support device and an antiemetic treatment device.

[0064] The body support device is used for the patient to sit or lie down in a preset body posture. Preferably, the body support part is a dynamic seat with adjustment functions, which can allow the patient to sit or lie down and can be adjusted according to the patient's body type.

[0065] The antiemetic treatment device includes the electronic antiemetic device in the aforementioned embodiment. When antiemetic treatment is required, electrostimulation treatment is performed on one or more target acupoints on one or more body parts of the patient through the electrode part of the electronic antiemetic device.

[0066] The body part may specifically include the head, abdomen, arm, leg, neck, back, waist, etc. For any of the foregoing body parts, after the position of the target acupoint with antiemetic effect is located, electrostimulation therapy can be performed on one or more target acupoints on one or more body parts of the patient through the electrode part of the electronic antiemetic device.

[0067] The method for locating the target acupoint can be manual positioning, that is, manually aligning the electrode part with the position of the target acupoint, or it can be system automatic positioning, that is, after the system identifies the position of the target acupoint on the body part, positioning is performed.

[0068] Preferably, as shown in Figure 6 The system further includes an acupoint recognition part provided corresponding to the body support device. The acupoint recognition part is used to recognize the positions of all acupoints on the patient's body part and locate the target acupoints with antiemetic effects therefrom.

[0069] In specific implementation, the acupoint recognition part may include an image acquisition structure and an image recognition structure. At this time, preferably, a body part placement position can be set on the body support device for a body part, such as an arm. The image acquisition structure can be set on the body part placement position. After obtaining the image data of the body part by scanning the body part on the placement position through the image acquisition structure, the name of the body part (such as the arm part) and the corresponding body part image data are sent to the foregoing image recognition structure.

[0070] The image recognition structure is configured to: obtain the body part size after recognizing the foregoing body part image data, and then based on the preset human acupoint information table of each body part, obtain the names and / or numbers, functions and corresponding position measurement information of each acupoint on the body part, and combine the obtained information to identify the acupoints with antiemetic effects on the body part as target acupoints and locate the positions of the target acupoints.

[0071] For other technical features of the electronic antiemetic device, refer to the description of the previous embodiment and will not be elaborated here.

[0072] In another implementation manner of this embodiment, the antiemetic treatment device may further include a massage unit for applying massage stimulation to the target acupoint.

[0073] As shown in Figure 7 The massage unit 200 at least includes a central area 210 and a peripheral area 220 surrounding the central area.

[0074] A first massage structure can be set in the central area 210, and the electrode part 100 of the electronic antiemetic device is set on the massage head of the first massage structure, and electrostimulation is performed on the position of the target acupoint through the electrode part 100.

[0075] A second massage structure may be provided in the peripheral area 220 for massaging and stimulating the target acupoint around the target acupoint position from the outside to the inside or from the inside to the outside around the acupoint.

[0076] In a preferred embodiment, the massage head of the first massage structure is a multi-layer nested structure. Refer to Figure 8 As shown, it may include an inner layer 211, a first rotating layer 212 sleeved outside the inner layer 211, and a second rotating layer 213 sleeved outside the first rotating layer 212. The electrode part 100 is arranged on the surface of the inner layer 211. The inner layer 211 can be telescopically adjusted relative to the first rotating layer 212, and the first rotating layer 212 can be telescopically adjusted relative to the second rotating layer 213.

[0077] The antiemetic treatment device is configured to: collect the size information of the patient's body part, determine the patient type according to the size information of the body part, and then adjust the telescopic state of each layer of the massage head according to the patient type to adjust the contact area between the massage head and the patient's skin.

[0078] Specifically, as a preference, the patient type may include a child type and an ordinary user type. At this time, the antiemetic treatment device is configured to: when it is determined that the patient is of the child type, the inner layer and the first rotating layer are in the extended state and in contact with the patient's skin, perform electrical stimulation through the inner layer, and rotate through the first rotating layer to perform skin massage. Refer to Figure 8 The right figure shown. When it is determined that the patient is of the ordinary user type, the inner layer and the first rotating layer are in the retracted state, perform electrical stimulation through the inner layer, and rotate through the first rotating layer and the second rotating layer to perform skin massage. Refer to Figure 8 The left figure shown.

[0079] Preferably, in the initial state, the inner layer 211 and the first rotating layer 212 of the massage head of the first massage structure are both in the retracted state. At this time, the surfaces of the inner layer 211, the first rotating layer 212, and the second rotating layer 213 are flush. When it is determined to be of the child type, control the inner layer and the first rotating layer to be in the extended state to contact the patient's skin In this embodiment, the massage stimulation is specifically preferably contraction and expansion massage. At this time, the second massage structure includes a massage head for realizing the contraction and expansion functions, and a liquid outlet hole is provided on the massage head. In this way, by performing massage around the target acupoint through the second massage structure, it can play a very good stretching role on the area around the target acupoint.

[0080] Correspondingly, a liquid delivery module is further included, which includes a liquid delivery path provided corresponding to the massage head, and the output end of the liquid delivery path is connected to the liquid outlet hole on the massage head.

[0081] The liquid delivery module is configured to: when receiving a liquid delivery instruction sent by the antiemetic treatment device, according to the massage head information in the liquid delivery instruction, control the liquid delivery path to communicate with the liquid outlet holes of the corresponding massage heads, and then deliver liquid to the corresponding massage heads.

[0082] The liquid can be, for example, massage lubricant, essential oil and other liquids. In this way, during massage, the liquid plays a role of lubrication assistance or meridian stimulation.

[0083] Preferably, the liquid delivery instruction may further include the single liquid delivery volume and liquid delivery cycle information. At this time, the liquid delivery module is configured to: when delivering liquid to the corresponding massage heads, measure the liquid delivery volume. When the delivered liquid volume reaches the aforementioned single liquid delivery volume, stop liquid delivery and wait for the next liquid delivery cycle; when the next liquid delivery cycle arrives, control liquid delivery again.

[0084] As a further preference, a plurality of first massage structures may be provided in the central area. The plurality of first massage structures are located in different orientations in the central area to form a plurality of massage sub-areas, and drive motors are respectively provided corresponding to each massage sub-area.

[0085] The antiemetic treatment device is configured to: based on a preset time period T1, within one time period T1, control the drive motors of each massage sub-area to start according to a preset central stimulation strategy, so as to drive the first massage structures of each massage sub-area to act to stimulate different orientations of the target acupoints; after the massage action within one time period T1 is completed, judge whether the massage time length of the target acupoint reaches a preset massage standard time; when it is determined that the massage standard time is not reached, enter the next time period T1 and repeat the aforementioned stimulation strategy; when it is determined that the massage standard time is reached, end the massage in the central area.

[0086] Specifically, the central area can be divided into a central sub-area and a plurality of corner sub-areas. The central stimulation strategy is configured to: within one time period T1, configure different stimulation parameters for the massage heads in the central sub-area and the corner sub-areas. Among them, the stimulation intensity of the central sub-area can be higher than that of the corner sub-areas.

[0087] As a further preference, a plurality of second massage structures may be provided in the peripheral area. The plurality of second massage structures form at least two massage annular zones in the peripheral area - see Figure 9 shown, which exemplifies the formation of the first massage annular zone sub-area 2201 and the first massage annular zone sub-area 2201. Second massage structures 221 are provided in different orientations of each massage annular zone to form massage annular zone sub-areas, and drive motors are respectively provided corresponding to each massage annular zone sub-area.

[0088] At this time, the antiemetic treatment device is configured to: based on a preset time period T2, within one time period T2, control the driving motors of each massage loop belt sub-region to start according to a preset peripheral stimulation strategy, so as to drive the second massage structures of each massage loop belt sub-region to act to stimulate the periphery of the target acupoint; after the massage action within one time period T2 is completed, judge whether the peripheral massage time length reaches a preset massage standard time; when it is determined that the massage standard time is not reached, enter the next time period T2 and repeat the foregoing peripheral stimulation strategy; when it is determined that the massage standard time is reached, end the peripheral area massage.

[0089] Preferably, the peripheral stimulation strategy is configured to: within one time period T2, configure different stimulation parameters for the massage heads in different massage loops. Specifically, for example, make the massage intensity of the massage heads of the inner massage loop higher than that of the massage heads of the outer massage loop, so as to produce a distinguishable massage effect.

[0090] Through the above technical solution, the electrical stimulation in the central area is combined with the massage stimulation in the peripheral area. While applying electrical stimulation to the acupoint, massage stimulation is applied through the massage unit to enhance the stimulation effect and further relieve or treat the vomiting symptoms of tumor chemotherapy patients. Specifically, the central area and the peripheral area are further divided into sub-regions. According to needs, it is possible to stimulate different orientations of the acupoint and the periphery of the acupoint. Optionally, a temperature difference can also be set in different areas, and the stimulation of the temperature difference is used to strengthen the stimulation effect.

[0091] In the above description, the disclosure of the present invention is not intended to limit itself to these aspects. Instead, within the scope of the target protection of this disclosure, each component can be selectively and operably combined in any number. In addition, terms such as "including", "comprising" and "having" should be defaulted to be interpreted as inclusive or open-ended, rather than exclusive or closed, unless it is explicitly defined to the contrary. All technical, scientific or other terms conform to the meaning understood by those skilled in the art, unless it is defined to the contrary. Common terms found in the dictionary should not be interpreted too idealistically or too unrealistically in the context of relevant technical documents, unless this disclosure explicitly defines it as such. Any changes and modifications made by those of ordinary skill in the art of the present invention fall within the protection scope of the claims.

Claims

1. An electronic antiemetic device based on electrical stimulation, characterized in that include: An electrode part, used for contacting an acupuncture point having an antiemetic effect on a body part of a patient and applying non-invasive electrical stimulation; A current pulse generating unit, electrically connected to the electrode unit, for generating a controllable current pulse and transmitting the current pulse to the electrode unit; The electrical stimulation control module is electrically connected to the current pulse generating unit and is used to control the operation of the current pulse generating unit; wherein, the electrical stimulation control module is configured to: receive electrical stimulation instructions, and according to the interval time and current pulse parameters configured in the electrical stimulation instructions, control the current pulse generating unit to intermittently enter the working state according to the interval time, and generate current pulses according to the aforementioned current pulse parameters.

2. The electronic antiemetic device according to claim 1, characterized in that: It includes a user interaction unit for collecting the electrical stimulation mode and current pulse parameters selected by the user; The electrical stimulation mode includes a continuous electrical stimulation mode and an interval electrical stimulation mode, which correspond to different electrical stimulation instructions respectively; The current pulse parameters include current pulse output duration and current pulse output intensity information; For the interval electrical stimulation mode, the current pulse output duration of the current pulse parameter includes the total working duration, the number of working cycles and the working duration of each working cycle.

3. The electronic antiemetic device according to claim 1, characterized in that: The electrode portion includes two electrode structures for contacting the patient's skin, the first electrode structure is a positive electrode, and the second electrode structure is a negative electrode; The electrode structure is a plant root structure, including a main electrode in the middle and peripheral root electrodes located on the periphery of the main electrode; electrode drive motors are provided corresponding to the main electrode and the peripheral root electrodes, for driving the electrode heads of the corresponding electrodes to extend and retract, and the electrode drive motors are connected to the electrical stimulation control module and receive control from the electrical stimulation control module; The electrical stimulation control module is configured as follows: when the working time of the current pulse generating unit arrives, the electrode driving motor is controlled so that each of the first electrode structure and the second electrode structure has an electrode head contacting the skin as a working electrode, forming a positive electrode and a negative electrode of the current loop respectively; and, during the application of electrical stimulation, the electrode driving motor is controlled to drive the electrode heads on the first electrode structure and the second electrode structure to contact or move away from the skin to adjust the working electrodes, and the electrode spacing for applying electrical stimulation is adjusted by adjusting the working electrodes.

4. The electronic antiemetic device according to claim 3, characterized in that: A working electrode dynamic adjustment control instruction is preset, and the working electrode dynamic adjustment control instruction is configured as follows: in an initial state, the main electrodes of the first electrode structure and the second electrode structure are used as working electrodes, and when a preset electrode adjustment cycle arrives, the working electrode of the first electrode structure is adjusted to one of the peripheral root electrodes, and the working electrode of the second electrode structure remains the main electrode unchanged, waiting for the next electrode adjustment cycle to arrive; When the next electrode adjustment cycle arrives, the working electrode of the first electrode structure is restored to the main electrode, and the working electrode of the second electrode structure is adjusted to one of the peripheral root electrodes. When the electrode adjustment cycle ends, the working electrode adjustment is terminated and restored to the aforementioned initial state. The electrical stimulation control module is configured to: execute the working electrode dynamic adjustment control instruction at least once when the current pulse generating unit is working; wherein, for the interval electrical stimulation mode, the working electrode dynamic adjustment control instruction is executed at least once in each working cycle.

5. The electronic antiemetic device according to claim 4, characterized in that: The electrical stimulation control module is further configured to: set different current pulse intensities when the main electrode and the peripheral root electrodes are used as working electrodes, and the current pulse intensity when the main electrode is used as the working electrode is higher than the current pulse intensity when the peripheral root electrodes are used as the working electrodes; as well as, When there are multiple peripheral root electrodes around the main electrode, the current pulse intensity of the outer root electrodes as working electrodes is higher than the current pulse intensity of the inner root electrodes as working electrodes.

6. The electronic antiemetic device according to claim 1, characterized in that: It also includes a patient status recognition module, which is in communication with the electrical stimulation control module and is configured to: collect the patient's physical status data during the electrical stimulation treatment, determine whether to continue to apply electrical stimulation according to the physical status data, and send an instruction to end electrical stimulation to the electrical stimulation control module when it is determined that electrical stimulation is not to be applied; When receiving the aforementioned instruction to end electrical stimulation, the electrical stimulation control module controls the current pulse generating unit to enter a standby state.

7. A chemotherapy and antiemetic treatment system, characterized in that: Body support device, used for patients to sit or lie in a preset body posture; An antiemetic treatment device comprises the electronic antiemetic device according to any one of claims 1 to 6, wherein the electrode portion of the electronic antiemetic device is used to perform electrical stimulation treatment on one or more target acupuncture points on one or more body parts of a patient.

8. The chemotherapy and antiemetic treatment system according to claim 7, characterized in that: The antiemetic treatment device further comprises a massage unit, the massage unit comprising at least a central area and a peripheral area surrounding the central area; The central area is provided with a first massage structure, and the electrode part of the electronic antiemetic device is provided on the massage head of the first massage structure for electrically stimulating the target acupuncture point position; The peripheral area is provided with a second massage structure for surrounding the target acupuncture point and massaging and stimulating the target acupuncture point from the outside to the inside or from the inside to the outside around the acupuncture point.

9. The chemotherapy and antiemetic treatment system according to claim 8, characterized in that: The massage head of the first massage structure is a multi-layer nested structure, including an inner layer, a first rotating layer sleeved outside the inner layer, and a second rotating layer sleeved outside the first rotating layer, the electrode part is arranged on the surface of the inner layer, the inner layer can be telescopically adjusted relative to the first rotating layer, and the first rotating layer can be telescopically adjusted relative to the second rotating layer; The antiemetic treatment device is configured to: collect size information of the patient's body parts, determine the patient type based on the size information of the body parts, and then adjust the telescopic state of each layer of the massage head according to the patient type to adjust the contact area between the massage head and the patient's skin; wherein, when the patient is a child type, the inner layer and the first rotating layer are in an extended state and contact the patient's skin, electrical stimulation is performed through the inner layer, and skin massage is performed by rotating the first rotating layer; when the patient is an ordinary user type, the inner layer and the first rotating layer are in a retracted state, electrical stimulation is performed through the inner layer, and skin massage is performed by rotating the first rotating layer and the second rotating layer.

10. The chemotherapy and antiemetic treatment system according to claim 9, characterized in that: The massage stimulation is a contraction and expansion massage, and the second massage structure includes a massage head for realizing the contraction and expansion functions, and the massage head is provided with a liquid outlet hole; It also includes a liquid delivery module, which includes a liquid delivery path corresponding to the massage head, and the output end of the liquid delivery path is connected to the liquid outlet hole on the massage head: the liquid delivery module is configured to: when receiving a liquid outlet instruction sent by the antiemetic treatment device, control the liquid delivery path to be connected to the liquid outlet hole of the corresponding massage head according to the massage head information in the liquid outlet instruction, and then deliver liquid to the corresponding massage head.

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