Cantilever type multifunctional machine
By designing a cantilever multi-function machine, using the cantilever shell flip and stirring and scraping device, the problems of large discharge residues and slow drying speed in the production of highly active biological drugs are solved, and the effects of clean discharge, fast drying and automated production are achieved.
Patent Information
- Application Number
- CN202510531869.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-25
- Publication Date
- 2025-06-27
AI Technical Summary
In the production of high-active biological drugs and new liquid crystal materials, existing multi-functional equipment has problems such as large discharge residues, slow drying speed, ball catching and online cleaning, and requires complex isolation equipment, resulting in complex operation and high cost.
A cantilever multi-function machine is designed, adopting an outer cantilever structure. The cantilever shell realizes washing, filtration, drying and crystallization of materials through flipping and stirring and scraping devices. The transmission device is arranged on the same side, and the clean outer shell is coated to form a clean shell, which facilitates the cleaning of the equipment.
The discharge residue is reduced to less than 50g or no residue, the drying speed is improved, the equipment operation and cleaning process is simplified, the requirements of GMP and FDA are met, and online automated production is realized.
Smart Images
Figure CN120204993A_ABST
Abstract
Description
Technical Field
[0001] The present invention belongs to the technical fields of biopharmaceuticals and high-purity new materials, and particularly relates to a cantilever multi-functional machine, which is mainly applied to the production of high-activity biopharmaceuticals of OEB4-5 and liquid crystal new materials, and is also applicable to the production of sterile powder pharmaceuticals. Background Art
[0002] At present, in the field of biopharmaceuticals, especially in the production of high-activity (OEB3-5) pharmaceuticals, such as cytotoxic and hormonal drugs, there are two difficult problems to solve. 1) Because the drugs are expensive, several kilograms per batch of materials, and several thousand yuan per gram of the drug, the residual discharge of the dried finished product has become a major problem that must be solved. 2) Because the high-activity drugs produced have high activity and toxicity, operators must be strictly isolated and protected, and must operate in a strictly sealed, negative-pressure environment and automatically. 3) It is necessary to meet various validation requirements for cleanliness, including requirements for on-line cleaning and disinfection of equipment. Therefore, the best way is to use a multi-functional device that does not require transfer and exposure throughout the process, that is, to complete crystallization, filtration, washing, drying, and automatic sealed discharge and transfer in one device without human intervention. At present, the minimum discharge residue of the best multi-functional device is 720 g (taking oxaliplatin as an example), and the loss per batch of materials is about 2 million. At the same time, there are various problems such as slow drying speed, caking of the receiving ball, and on-line cleaning. There are also problems in the need to configure complex isolation equipment, which brings derivative problems of the isolation equipment. Summary of the Invention
[0003] In view of the above technical problems, the present invention provides a cantilever multi-functional machine, which has an outer cantilever structure. The transmission devices for the rotation of the main shaft of the cantilever housing flipping and the stirring and scraping device are arranged on the same side, and are covered with a clean outer shell to form a clean housing, which is convenient for cleaning the equipment. On the other side is an outer cantilever multi-functional pharmaceutical housing, which provides sufficient operating space, and viewing mirrors, isolation glove holes, feed ports, cleaning ports, temperature and pressure detection ports, vibrators, etc. can be arranged at the most convenient positions according to operating requirements.
[0004] The object of the present invention is achieved by the following technical solutions:
[0005] A cantilever multi-functional machine of the present invention includes a base, a cantilever housing, a stirring and scraping device, and a housing flipping device. The cantilever housing is composed of a cavity with a hemispherical shape and a conical or flat-bottom cavity connected to each other, and is respectively provided with a feed port and a discharge port thereon. The housing flipping device is connected to the base through a bearing support, and one end of a hollow housing transmission shaft rotatably connected to the bearing support is connected to the cantilever housing, and the other end of the hollow housing transmission shaft is connected to a housing power mechanism, which drives the hollow housing transmission shaft to drive the cantilever housing to flip. The main shaft of the stirring and scraping device is rotatably connected inside the hollow housing transmission shaft, one end extends into the cantilever housing, and a plurality of paddle blades are arranged thereon, which cooperate with the inner wall of the cavity with a hemispherical shape for stirring and scraping. The other end passes through the transmission shaft and is connected to a main shaft heating rotary seal, and the main shaft is connected to a main shaft power mechanism. When the conical or flat-bottom cavity in the cantilever housing is flipped to the lower side to form an inverted conical or flat-bottom cavity, the washing and filtering of materials are carried out. When the cavity with a hemispherical shape is flipped to the lower side, the drying and / or crystallization of materials are carried out.
[0006] Further, the housing flipping device includes a hollow housing transmission shaft and a housing power mechanism. One end of the transmission shaft is connected to the cantilever housing through a housing connection seat, and the other end is connected to the bearing support through a bearing I. The housing power mechanism includes a flipping drive motor, a housing gear, and a reducer gear. A housing gear is installed on the hollow housing transmission shaft, and a reducer gear drivingly connected thereto is installed on the output shaft of the flipping drive motor. The hollow housing transmission shaft is driven by the flipping drive motor to drive the cantilever housing to flip.
[0007] Further, the main shaft is connected to the housing connection seat of the cantilever housing through a mechanical seal, realizing a sealed isolation from the inner cavity of the cantilever housing.
[0008] Further, the scraping end of the scraping paddle blade is an arc corresponding to the scraping part corresponding to the inner wall of the hemispherical body, and the running tracks of a plurality of scraping paddle blades cover the entire inner wall of the hemispherical body.
[0009] Further, on one side of the scraping paddle blade located in the middle part of the main shaft, there is an inclined plate, and the inclined plate forms an angle less than 90 degrees with the tangent of the rotation track, rotating and compressing the filter cake of the filtered material.
[0010] Further, the gap between the scraping end of the scraping paddle blade and the inner wall of the hemispherical body is 0.5 - 10 mm.
[0011] Further, the conical or flat-bottom cavity is sequentially provided with a filter layer, a filter liquid recovery jacket, a heating layer, and a heat preservation outer shell from the inside to the outside. A liquid recovery cavity is formed between the filter layer and the filter liquid recovery jacket, and a filter liquid outlet and a vacuum connection port are respectively opened on the filter liquid recovery jacket. A discharge valve is arranged at the bottom of the conical or flat-bottom cavity. The materials are filtered and washed, and the filtered liquid flows out through the filtrate outlet, and the solid is discharged through the discharge valve.
[0012] Further, the filter layer, i.e., the inner sidewall of the cavity, is a filter plate or a filter cloth. A vibrator and / or a backwashing port are also provided on the outer wall of the cavity. The backwashing port is connected to a gas source to vibrate and / or backwash the filter cake adhering to the inner sidewall of the conical or flat-bottomed cavity.
[0013] Further, the cavity with a hemispherical shape is composed of a hemispherical body and a transition section. A hemispherical inner liner, a hemispherical heating layer, and a hemispherical heat-insulating outer shell are sequentially arranged from the inside to the outside for heating, drying, or crystallization of the material. The hemispherical heating layer is connected to a heat source. A glove isolation port and / or a sight glass lamp mirror are also provided on the transition section.
[0014] The usage method of the cantilever type multi-functional machine of the present invention, the filtration, washing, and drying processes include the following steps:
[0015] S1: In the initial stage, the conical or flat-bottomed cavity in the cantilever type housing is placed below, and the solid-liquid mixed slurry falls into the conical or flat-bottomed cavity through its feed port for pressure filtration or suction filtration.
[0016] S2: Then, the material cleaning liquid enters the conical or flat-bottomed cavity through the cleaning liquid port to wash the material, and secondary suction filtration or pressure filtration is performed.
[0017] S3: After washing n times according to step S2, n≥1, the material is pressed dry to obtain a qualified filter cake and wait for drying.
[0018] S4: Rotate the cantilever type housing 180 degrees so that the conical or flat-bottomed cavity faces upward, and the filter cake to be dried falls into the lower hemispherical body by gravity.
[0019] S5: Turn on the vibrator and blow gas through the backwashing port to pass the filter cake adhering to the inner surface of the conical or flat-bottomed cavity and fall into the hemispherical body.
[0020] S6: Heat and evacuate the cantilever type housing, and drive the paddle by the main shaft to stir and dry the material to obtain a qualified filter cake product. The material is automatically pushed out of the cantilever type housing by scraping the paddle of the main shaft to complete a working cycle.
[0021] If crystallization is required, before step S1, first turn the conical or flat-bottomed cavity in the cantilever type housing to the upper side and the cavity with a hemispherical shape to the lower side. The crystallization liquid enters the cavity with a hemispherical shape through the feed port, turn on the stirring and scraping device, and perform the processes of heating and cooling to complete crystallization; then perform steps S1 to S6 for filtration, washing, and drying to complete the whole process of crystallization, filtration, washing, and drying.
[0022] The beneficial effects of the present invention are:
[0023] 1. The present invention sets a housing flipping device and a stirring and scraping device on the same side, with a clean outer shell covering it, and an outer cantilever multi-functional cantilever housing is set on the other side as a pharmaceutical housing. The cantilever design of the housing is more conducive to the isolation of the clean area, preventing the transmission pollution of the clean area. For the discharging and transferring operation, it is convenient to connect to a silo, a sterile barrel, and a vacuum conveying device. The main shaft of the stirring and scraping device is rotationally connected inside the transmission shaft of the housing flipping device, and the transmission shaft and the main shaft are respectively connected to their own power mechanisms, enabling the main shaft and the transmission shaft to rotate independently, respectively realizing the scraping of materials inside the cantilever housing and the flipping of the cantilever housing to meet different process requirements.
[0024] 2. The present invention adopts a cantilever housing composed of a cavity with a hemispherical shape and a conical or flat-bottom cavity connected. When the conical or flat-bottom cavity in the cantilever housing is flipped to the lower side to form a conical or flat-bottom cavity, the washing and filtering of materials are carried out. When the cavity with a hemispherical shape is flipped to the lower side, the drying and / or crystallization of materials are carried out. The hemispherical design has the characteristic of fast drying; the conical or flat-bottom cavity has the advantage of a large filtering area.
[0025] 3. The discharge port of the present invention is arranged at the lower end of the conical or flat-bottom cavity. When the conical or flat-bottom cavity rotates to the lower side to form a conical or flat-bottom cavity, discharging occurs, and the auxiliary isolation gloves are used to clean the residue, which has the advantage of clean discharging. The residue of the discharged finished product can be reduced to within 50 g or achieve the effect of no residue.
[0026] 4. The cavity with a hemispherical shape of the present invention is smooth and has no dead corners, which is convenient for heating and drying, improving the heating uniformity and heat exchange efficiency of the medicine. The outer surface is smooth and has no dead corners, which is conducive to CIP on-line cleaning and SIP on-line sterilization, and surface cleaning certification conditions, fully meeting the requirements of pharmaceutical production GMP and FDA.
[0027] 5. The equipment of the present invention can realize on-line automated production, and can achieve intelligent production after debugging parameters.
[0028] 6. The equipment of the present invention is more suitable for the production of small batches of medicines. The cantilever housing with a cantilever design is light in weight, which is convenient for implementation and operation. BRIEF DESCRIPTION OF THE DRAWINGS
[0029] Figure 1 is a schematic structural diagram of the present invention.
[0030] Figure 2 is Figure 1 the left view of
[0031] Figure 3 is Figure 1 the top view of
[0032] Figure 4 is Figure 1 the sectional view taken along the line A-A of
[0033] In the figure: 1. Rotary seal for the main shaft heat source, 2. Driving sprocket of the main shaft, 3. Bearing Ⅰ, 4. Bearing support, 5. Positioning sleeve, 6. Hollow transmission shaft of the housing, 7. Mechanical seal, 8. Connecting seat of the housing, 9. Exhaust port, 10. Hemispherical heat-insulating outer shell, 11. Hemispherical heating layer, 12. Hemispherical inner liner, 13. Paddle, 14. Main shaft, 15. Chuck, 16. Conical heat-insulating outer shell, 17. Conical heating layer, 18. Filtered liquid recovery jacket, 19. Filter layer, 20. Discharge valve, 21. Base, 22. Reducer sprocket, 23. Transmission chain, 24. Reducer Ⅰ, 25. Main shaft drive motor, 26. Tipping drive motor, 27. Reducer Ⅱ, 28. Reducer gear, 29. Housing gear, 30. Heat source outlet of the housing, 31. Filtered liquid outlet, 32. Heat source inlet of the housing, 33. Feed port, 34. Cleaning port, 35. Glove isolation interface, 36. Lamp mirror sight glass, 37. Vibrator, 38. Vacuum connection port, 39. Sampling port, 40. Temperature detection port, 41. Pressure detection port, 42. Equipment outer shell, 43. Bearing Ⅱ. Specific embodiments
[0034] The present invention will be described in detail below with reference to the accompanying drawings and embodiments.
[0035] Embodiment 1: As Figure 1-3 shown, a cantilever multi-functional machine of the present invention includes a base 21, a cantilever housing, a stirring and scraping device, and a housing tipping device. One end of the spherical-conical special-shaped cavity is cantilever unsupported. The cantilever housing is formed by connecting a cavity with a hemispherical shape and a conical cavity, and is respectively provided with a feed port 33, a discharge port, a cleaning port 34, and an exhaust port 9. The housing tipping device is connected to the base 21 through a bearing support 4. One end of a hollow transmission shaft 6 of the housing rotatably connected to the bearing support 4 is connected to the cantilever housing. The hollow transmission shaft 6 of the housing is connected to a housing power mechanism, and the cantilever housing is driven to tip by driving the hollow transmission shaft of the housing through the housing power mechanism. The main shaft 14 of the stirring and scraping device is rotatably connected inside the hollow transmission shaft 6 of the housing. One end of the main shaft 14 extends into the cantilever housing, and a plurality of paddles 13 are arranged thereon, which cooperate with the inner wall of the cavity with a hemispherical shape for stirring and scraping. The other end of the main shaft 14 passes through the hollow transmission shaft 6 of the housing tipping device, and a main shaft heating rotary seal 1 is connected thereto. The main shaft power mechanism is connected to and drives the main shaft 14 to drive the paddles to rotate, so as to realize stirring and scraping the inner wall of the cantilever housing. When the conical cavity in the cantilever housing is tipped to the lower side to form a conical cavity, the washing and filtering of materials are carried out. When the cavity with a hemispherical shape is tipped to the lower side, the drying and / or crystallization of materials are carried out.
[0036] The housing flipping device includes a housing hollow transmission shaft 6 and a housing power mechanism. One end of the housing hollow transmission shaft 6 is connected to the cantilever housing through a housing connection seat 8, and the other end is connected to a bearing support 4 through two bearing I 3. The housing power mechanism includes a flipping drive motor 26, a reducer II 27, a housing gear 29, and a reducer gear 28. The housing gear 29 is installed on the transmission shaft. The flipping drive motor 26 is connected to the reducer II 27, and the reducer gear 28 that is in transmission connection with it is installed on the output shaft of the reducer II 27. The flipping drive motor 26 drives the reducer II 27, the reducer gear 28, the housing gear 29, and the housing hollow transmission shaft 6 to rotate, driving the cantilever housing to flip.
[0037] All the weight of the cantilever housing is transmitted to the bearing support 4 through the housing hollow transmission shaft 6 and two bearing I 3. The bearing support 4 is installed on the base 21, and finally all the loads are borne by the base 21.
[0038] The stirring and scraping device includes a main shaft 14, a main shaft power mechanism, a mechanical seal 7, a bearing II 43, and a paddle 13. The main shaft 14 is installed in the housing hollow transmission shaft 6 through the bearing II 43. The main shaft 14 is connected to the housing connection seat 8 placed on the cantilever housing through the mechanical seal 7 and extends into the inner cavity of the cantilever housing, achieving a sealed isolation from the inner cavity of the cantilever housing. A plurality of scraping paddles 13 are provided on the main shaft 14 extending into the inner cavity of the cantilever housing. The main shaft power mechanism includes a main shaft drive motor 25, a reducer I 24, a main shaft drive sprocket 2, a reducer drive sprocket 22, and a chain 23. The main shaft drive sprocket 2 is provided on the main shaft 14, the reducer drive sprocket 22 is provided on the output shaft of the reducer I 24, and the chain 23 is sleeved on the main shaft drive sprocket 2 and the reducer drive sprocket 22. The input shaft of the reducer I 24 is connected to the main shaft drive motor 25. The main shaft drive motor 25 drives the reducer I 24 to drive the sprocket and chain to rotate, and then drives the main shaft 14 to rotate, realizing the scraping of the inner wall of the cantilever housing by the paddle 13 and stirring.
[0039] The main shaft 13 is a cantilever shaft in the inner cavity of the cantilever housing. The end face of the mechanical seal 7 is fixed on the housing connection seat 8. The dynamic ring of the mechanical seal 7 rotates together with the main shaft 13, and the static ring is connected to the housing connection seat 8 and rotates with the cantilever housing. The main shaft heating rotary seal 1 connected to the end of the main shaft 14 is connected to a heat source. The heat source realizes heating or cooling of the main shaft 14 through the inlet and outlet of the main shaft heating rotary seal 1, realizing heating, rotation, and sealing of the main shaft. The main shaft 14 acts on the bearing support 4 through two bearing II 43, the transmission shaft 6, and the bearing 3. The bearing support 4 is fastened on the base 21. The load of the main shaft 14 is sequentially transmitted to the base 21 through two bearing II 43, the transmission shaft 6, and the bearing support 4. All the loads are borne by the support 21 to ensure its stable operation. The mechanical seal 7, the main shaft rotary seal 1, the bearing support 4, the bearing I 3, and the bearing II 43 are all existing general accessories and will not be elaborated here.
[0040] Among them, the speed reducer I 24 connected to the main shaft drive motor 25 and the speed reducer II 27 connected to the tilting drive motor 26 can be hydraulic motors. Positioning sleeves 5 (prior art) are respectively arranged between the two bearings I 3 and between the two bearings II 43 to position the bearings I 3 and the bearings II 43. The main shaft 14 and the transmission shaft 6 are respectively driven by their respective power mechanisms and rotate independently.
[0041] The scraping end of the paddle 13 is an arc corresponding to the scraping part on the inner wall of the hemispherical body, and the running tracks of the multiple scraping paddles 13 cover the entire inner wall of the inner spherical shell 12.
[0042] On one side of the scraping paddle 13 in the middle part of the main shaft 14, there is an inclined plate, and the inclined plate forms an angle α less than 90 degrees with the tangent of the rotation track to rotationally compact the turtle cracks on the upper surface of the filter cake of the filtered material.
[0043] The gap between the scraping end of the paddle 13 and the inner wall of the inner spherical shell 12 is 0.5 - 10 mm, optimally 2 - 5 mm, and in this example, it is 2 mm. The entire area of the inner wall of the hemispherical body is scraped by the main shaft 14 and the scraping paddle 13 thereon.
[0044] In this example, the cavity with a hemispherical shape and the bottom edge of the conical cavity are connected by a flange or a chuck 12 to form a structure with one end being conical and the other end being hemispherical. An outlet is opened at the conical end, and an outlet valve 5 is arranged thereon.
[0045] The cavity with a hemispherical shape is composed of a hemispherical body and a transition section. A hemispherical inner liner 12, a hemispherical heating layer 11, and a hemispherical heat preservation outer shell 10 are sequentially arranged from the inside to the outside for heating, drying, or crystallization of the material. The material inlet 33 and the cleaning port 34 are opened on the transition section. A glove isolation interface 35 and / or a sight glass lamp mirror 36 are also arranged on the transition section. The glove isolation interface 35 is used for manual operation, and the sight glass lamp mirror 36 is used for observation and illumination. Among them, the hemispherical heating layer 11 of the cavity with a hemispherical shape is connected to a heat source for heating; the hemispherical heat preservation outer shell 10 adopts existing heat preservation materials to better maintain the temperature of the cavity with a hemispherical shape, which is beneficial to drying or crystallization.
[0046] The inside of the hemispherical body is smooth without dead corners, has good geometric symmetry, is easy to achieve full - area scraping, and is beneficial to heat transfer and drying. The present invention also has a sampling port 39, a temperature detection port 40, and a pressure detection port 41 on the cavity with a hemispherical shape. An on - line sampler is arranged on the sampling port 39 for real - time sampling; the temperature detection port 40 and the pressure detection port 41 are respectively used for temperature and pressure detection.
[0047] The side wall of the conical cavity is composed of a filter layer 19, a filtrate recovery jacket 18, a heating layer 17, and a heat preservation outer shell 16 from the inside to the outside. A liquid recovery cavity is formed between the filter layer 19 and the filtrate recovery jacket 18. A filtrate outlet 31 and a vacuum connection port 38 are respectively opened on the filtrate recovery jacket 18 at the bottom of the conical cavity. 17 is a heating jacket or a half pipe or other heating structure, and 16 is a heat preservation outer shell.
[0048] Both the hemispherical heating layer 11 and the heating layer 17 are provided with a shell heat source inlet 32 and a shell heat source outlet 30 (illustrated with a cavity with a hemispherical shape as an example). The heat source is circulated through the shell heat source inlet 32 and the shell heat source outlet 30 for heating or cooling the cantilever shell.
[0049] A discharge valve 5 is arranged at the bottom of the conical cavity, and the solid powder is discharged through the discharge valve 5; the filtrate of the conical filter layer 19 is discharged through the filtrate outlet 31, and the air in the shell is pumped out through the vacuum connection port 38 during drying.
[0050] The filter layer 19, that is, the inner side wall of the conical cavity, is a conical filter plate or a filter cloth. A vibrator 37 and an anti-blowing port are also arranged on the outer wall of the conical cavity. The anti-blowing port is connected to a gas source, and the filter cake attached to the inner side wall of the conical cavity is vibrated by the vibrator 37 and / or blown back through the anti-blowing port.
[0051] The conical cavity can achieve a large volume and a large filter area design, which is beneficial to solid-liquid separation by filtration. A powder discharge valve is arranged at the bottom of the inverted conical cavity, and the material is completely discharged under vibration and back blowing.
[0052] The conical cavity described in the present invention can be designed into a conical body or a transitional flat-bottom cavity according to different materials. By adjusting the height and diameter of the conical cavity or the flat-bottom cavity, the ratio of the heating area to the filter area can be set arbitrarily to meet the requirements of different process materials.
[0053] The usage method of the ball-cone special-shaped multi-functional machine described in the present invention for the processes of filtration, washing, and drying includes the following steps:
[0054] S1: In the initial stage, the drive shaft 6 is driven by the shell flipping device, and the cantilever shell is driven to rotate until the conical cavity is placed below. The solid-liquid mixed slurry falls into the conical cavity through its feed port 33, and pressure filtration or suction filtration is carried out to achieve solid-liquid separation. The separated solid remains in the conical cavity, and the liquid is discharged out of the shell through the liquid recovery cavity.
[0055] S2: Then, the material cleaning liquid enters the conical cavity through the cleaning port 34 to wash the material, and secondary suction filtration or pressure filtration is carried out. The separated solid remains in the conical cavity, and the liquid is discharged out of the vertebral heat preservation outer shell 16 through the liquid recovery cavity to obtain a qualified filter cake and wait for drying.
[0056] S3: After washing n times according to step S2, where n ≥ 1 and the number of washing times depends on the production process requirements, press dry the material to obtain a qualified filter cake and wait for drying.
[0057] S4: Drive the transmission shaft 6 through the housing flipping device to drive the cantilever housing to rotate 180 degrees, making the conical cavity face upward, and the filter cake to be dried falls into the lower hemispherical body by gravity.
[0058] S5: Turn on the vibrator 37, blow in gas through the backflush port, and let the filter cake attached to the inner surface of the conical cavity pass through and fall into the hemispherical body.
[0059] S6: Heat and evacuate the cantilever housing, and drive the paddle 13 through the main shaft 14 to stir and dry the material to obtain a qualified dried product. Then, automatically push the material out of the cantilever housing through the main shaft scraping paddle 13 to complete one working cycle.
[0060] When crystallization is required, first flip the conical cavity in the cantilever housing upward and the cavity with a hemispherical shape downward. The crystallization liquid enters the cavity with a hemispherical shape through the feed port 33. Turn on the stirring and scraping device, and perform the heating and cooling processes to complete crystallization. Then, perform the S1 - S6 filtration, washing, and drying steps to complete the entire process of crystallization, filtration, washing, and drying.
[0061] Embodiment 2: The difference between this example and Embodiment 1 is that in this example, the cantilever housing is composed of a cavity with a hemispherical shape and a flat bottom cavity connected. The cavity with a hemispherical shape and the flat bottom cavity are connected by a flange or a chuck 12 to form a structure with a circular end and a flat bottom end. An outlet is opened at the flat bottom end, and an outlet valve is provided thereon.
[0062] The filter layer provided on the side wall of the flat bottom cavity is a filter plate, which uses an existing microporous filter material plate; the gap between the scraping end of the scraping paddle and the inner wall of the hemispherical body is 2 mm.
[0063] This spherical - conical special - shaped multi - functional machine in this example is used for crystallization, filtration, washing, and drying, and its usage method is as follows:
[0064] First, perform the crystallization work. Flip the flat bottom cavity in the cantilever housing upward and the cavity with a hemispherical shape downward. The crystallization liquid enters the cavity with a hemispherical shape through the feed port. Turn on the stirring and scraping device, and perform the heating and cooling processes to complete crystallization. Then, perform the S1 - S6 filtration, washing, and drying steps in Embodiment 1 to complete the entire process of crystallization, filtration, washing, and drying.
[0065] Embodiment 3: The difference between this example and Embodiment 1 is that in this example, the filter layer provided on the side wall of the conical cavity is a conical filter cloth, and the gap between the scraping end of the scraping paddle and the inner wall of the hemispherical body is 10 mm.
[0066] Example 4: The difference between this example and Example 1 is that the filter layer provided on the side wall of the conical cavity in this example is a conical filter cloth, and the gap between the scraping end of the scraping blade and the inner wall of the hemispherical body is 3 mm.
[0067] Example 5: The difference between this example and Example 1 is that the filter layer provided on the side wall of the conical cavity in this example is a conical filter cloth, and the gap between the scraping end of the scraping blade and the inner wall of the hemispherical body is 2 mm.
[0068] The components not described in detail in this application are all conventional existing technologies and will not be elaborated here.
[0069] It can be understood that the above specific description of the present invention is only for explaining the present invention and is not limited to the technical solutions described in the embodiments of the present invention. Those of ordinary skill in the art should understand that the present invention can still be modified or equivalently replaced to achieve the same technical effects; as long as it meets the usage requirements, it is within the protection scope of the present invention.
Claims
1. A cantilever multifunctional machine, characterized in that: It includes a base, a cantilever shell, a stirring and scraping device and a shell flipping device. The cantilever shell is composed of a cavity with a hemispherical shape and a conical or flat-bottom cavity, and a feed port and a discharge port are respectively opened on it; the shell flipping device is connected to the base through a bearing support, one end of the hollow transmission shaft of the shell rotatably connected to the bearing support is connected to the cantilever shell, and the other end of the hollow transmission shaft of the shell is connected to the shell power mechanism, and the hollow transmission shaft of the shell is driven to drive the cantilever shell to flip; the main shaft of the stirring and scraping device is rotatably connected to the hollow transmission shaft of the shell, one end of which extends into the cantilever shell, and a plurality of paddles are arranged on it, which cooperate with the inner wall of the cavity with a hemispherical shape for stirring and scraping, and the other end passes through the transmission shaft to connect the main shaft heating rotary seal, and the main shaft is connected to the main shaft power mechanism; when the conical or flat-bottom cavity in the cantilever shell flips to the bottom to form an inverted cone or flat-bottom cavity, the material is washed and filtered, and when the cavity with a hemispherical shape flips to the bottom, the material is dried and / or crystallized.
2. The cantilever multifunctional machine according to claim 1, characterized in that: The shell flipping device includes a hollow transmission shaft of the shell and a shell power mechanism. One end of the transmission shaft is connected to the cantilever shell through a shell connecting seat, and the other end is connected to the bearing support through a bearing I. The shell power mechanism includes a flipping drive motor, a shell gear and a reducer gear. The shell hollow transmission shaft is installed with a shell gear, and the reducer gear connected to the output shaft of the flipping drive motor is installed with the reducer gear connected to the flipping drive motor. The flipping drive motor drives the hollow transmission shaft of the shell to drive the cantilever shell to flip.
3. The cantilever multifunctional machine according to claim 1, characterized in that: The main shaft is placed on the shell connecting seat of the cantilever shell through a mechanical seal connection, and is sealed and isolated from the inner cavity of the cantilever shell.
4. The cantilever multifunctional machine according to claim 1, characterized in that: The scraping ends of the scraping blades are arc-shaped corresponding to the scraping positions of the inner wall of the hemispherical body, and the running tracks of the multiple scraping blades cover the entire inner wall of the hemispherical body.
5. The cantilever multifunctional machine according to claim 1 or 4, characterized in that: A side of the scraping blade located in the middle part of the main shaft is provided with an inclined plate, and the inclined plate forms an angle less than 90 degrees with the tangent of the rotation track, so as to rotate and compact the filter cake of the filtered material.
6. The cantilever multifunctional machine according to claim 1 or 4, characterized in that: The gap between the scraping end of the scraping blade and the inner wall of the hemispherical body is 0.5-10 mm.
7. The cantilever multifunctional machine according to claim 1, characterized in that: The conical or flat-bottomed cavity is provided with a filter layer, a filtrate recovery jacket, a heating layer, and a heat-insulating shell in sequence from the inside to the outside, a liquid recovery cavity is formed between the filter layer and the filtrate recovery jacket, and a filtrate outlet and a vacuum connection port are respectively provided on the filtrate recovery jacket; a discharge valve is provided at the bottom of the conical or flat-bottomed cavity, the material is filtered and washed, the filtered liquid flows out through the filtrate outlet, and the solid is discharged through the discharge valve.
8. The cantilever multifunctional machine according to claim 7, characterized in that: The filter layer, i.e. the inner wall of the cavity, is a filter plate or filter cloth. A vibrator and / or a back-blowing port is also provided on the outer wall of the cavity. The back-blowing port is connected to an air source to vibrate and / or back-blow the filter cake attached to the inner wall of the conical or flat-bottomed cavity.
9. The cantilever multifunctional machine according to claim 1, characterized in that: The hemispherical cavity is composed of a hemispherical body and a transition section, and is provided with a hemispherical inner liner, a hemispherical heating layer and a hemispherical heat-insulating outer shell in sequence from the inside to the outside, and is used for heating, drying or crystallizing materials. The hemispherical heating layer is connected to a heat source, and a glove isolation port and / or a sight glass light mirror are also provided on the transition section.
10. A method for using the cantilever multifunctional machine according to any one of claims 1 to 9, characterized in that: The filtering, washing and drying process includes the following steps: S1: In the initial stage, the conical or flat-bottomed cavity in the cantilevered shell is placed at the bottom, and the solid-liquid mixed slurry falls into the conical or flat-bottomed cavity through its feed port for pressure filtration or suction filtration; S2: The material cleaning liquid enters the conical or flat-bottomed cavity through the cleaning liquid port to wash the material and perform secondary suction filtration or pressure filtration; S3: After washing n times according to step S2, n≥1, the material is pressed dry to obtain a qualified filter cake, and then wait for drying; S4: Rotate the cantilever housing 180 degrees so that the conical or flat-bottomed cavity faces upward, and the filter cake to be dried falls into the hemispherical body at the bottom by gravity; S5: Turn on the vibrator and blow gas through the back-blowing port to pass the filter cake attached to the inner surface of the conical or flat-bottomed cavity and fall into the hemispherical body; S6: The cantilever housing is heated and vacuumed, and the main shaft drives the paddles to stir and dry the materials to obtain qualified filter cake products. The main shaft scrapes the paddles to automatically push the materials out of the cantilever housing to complete a working cycle; If crystallization is required, before step S1, the conical or flat-bottomed cavity in the cantilever shell is turned upward, and the hemispherical cavity is turned downward, and the crystal cleaning liquid enters the hemispherical cavity through the feed port, the stirring and scraping device is turned on, and the heating and cooling processes are performed to complete the crystallization; then the filtering, washing, and drying steps S1 to S6 are performed to complete the entire process of crystallization, filtering, washing, and drying.