Automatic sampling device for liquid chromatograph

Abstract

The present application relates to the field of liquid chromatographs, and more specifically to an automatic sampling device for a liquid chromatograph. To address the issue of touching the internal structure of the device during the sampling process, the device comprises a housing, a sample placement area disposed within the housing, and a plurality of rows of sample placement strips disposed within the sample placement area away from the sampling area; an injection housing disposed on one side of the housing, and an injection port and an outlet disposed on the side of the housing proximal to the housing, with the injection port located between the outlet and the sampling area; a transmission assembly disposed within the injection housing for transporting the sample placement strips, a discharge assembly disposed within the injection housing for removing samples from sample placement strips after sampling, and a loading assembly disposed within the injection housing for placing new samples on empty sample placement strips; and a guide assembly disposed within the housing for transporting sample placement strips after sampling to the transmission assembly. The present application has the effect of reducing the risk of touching the internal structure of the device during the sampling process.

Description

Technical Field

[0001] The present application relates to the field of liquid chromatographs, and in particular to an automatic sampling device for liquid chromatographs. Background Art

[0002] Liquid chromatography is an instrument that uses the difference in the distribution ratio of a mixture between liquid and solid or between two immiscible liquids to first separate the mixture and then analyze and identify it.

[0003] When using a fully automatic chromatograph, the experimenter needs to place the samples to be sampled on the sample tray in advance, and then after closing the protective door, the robot will clamp the several samples placed on the sample tray one by one to the sampling area for sampling.

[0004] When the experimenter places the sample on the sample tray, his hands cannot touch the robot that takes the sample. At the same time, when the number of samples is small, the operator needs to place them in the same column as much as possible. Placing them in the same column requires the operator to reach inward, which makes it very easy to touch the robot. Therefore, this needs to be improved. Summary of the Invention

[0005] In order to reduce the touching of the internal structure of the device during the injection process, the present application provides an automatic injection device for a liquid chromatograph.

[0006] The present application provides an automatic sample injection device for a liquid chromatograph using the following technical solutions:

[0007] An automatic sampling device for a liquid chromatograph comprises a casing, wherein a sample placement area is provided in the casing, and a plurality of rows of sample placement strips are provided in the sample placement area away from the sampling area; an injection shell is provided on one side of the casing, and an injection port and an outlet port are provided on the side of the injection shell close to the casing, wherein the injection port is located between the outlet port and the sampling area; a transmission component for transporting the sample placement strips is provided in the injection shell, a discharging component for removing samples from the sample placement strips after sampling is also provided in the injection shell, and a loading component for placing new samples on empty sample placement strips is also provided in the injection shell; and a guide component for transporting the sample placement strips after sampling is completed to the transmission component is provided in the casing.

[0008] By adopting the above technical solution, the assembled samples are loaded by the loading component and the samples to be sampled are loaded onto the empty sample placement strips at the transmission component. Even if the samples are not placed continuously on the sample placement strips, the sample placement strips still move under the transmission of the transmission component and finally enter the housing from the sampling port. The sample placement strips containing the samples to be sampled are placed in a row near the sampling area. The manipulator grabs the samples to be sampled in sequence and takes them to the sampling location for sampling. After the sampling is completed, the samples are put back into the sample placement strips. After all the samples on the sample placement strips are sampled, they are guided to the sample outlet by the guide component and transported by the transmission component. During the transmission process, the unloading component unloads the sample from the sample placement strip. The empty sample placement strip moves under the action of the transmission component and is loaded by the loading component. Repeating the above steps can realize automatic sampling. The injection port and the outlet port are set in the injection shell, and the injection port is located between the outlet port and the sampling area. With the design of the transmission component, the unloading component and the loading component, a complete sample flow path is formed, which improves the operation efficiency of the entire system. The existence of the guide component ensures that the sample placement strip can be accurately transferred to the transmission component after sampling is completed, further ensuring the smoothness and stability of the system operation.

[0009] Preferably, the transmission component includes a sample outlet guide rail, a sample injection guide rail, a transfer guide rail and a transmission component, the sample outlet guide rail and the sample injection guide rail are parallel, one end of the sample outlet guide rail is arranged at the sample outlet, one end of the sample injection guide rail is arranged at the sample injection port, one end of the transfer guide rail is connected to the end of the sample outlet guide rail away from the sample outlet, and the other end is connected to the end of the sample injection guide rail away from the sample injection port; a transmission component is provided on one side of the sample outlet guide rail and the sample injection guide rail, which is used to transmit the sample placement strip to move on the sample outlet guide rail and the sample injection guide rail.

[0010] By adopting the above technical solution, the design of the transport assembly enables the sample placement strip to move smoothly along a pre-set path, eliminating the risk of contact caused by manual intervention. Furthermore, the combined layout of the sample discharge guide, sample inlet guide, and transfer guide ensures the stability of the sample placement strip throughout the entire transport process, effectively reducing equipment collisions caused by positional deviation, thereby significantly improving the safety and reliability of the automatic sample injection device. This ensures the orderly transfer of the sample placement strip between the sample inlet and outlet.

[0011] Preferably, the transmission member is a transmission gear, the transmission gear at the sample outlet guide rail is rotatably connected to one end of the sample outlet guide rail close to the sample outlet, and the transmission gear at the sample injection guide rail is rotatably connected to one end of the sample injection guide rail away from the sample injection port; one of the transmission gears is externally connected to a motor, and the two transmission gears are connected by a transmission structure; the side walls of the sample placement strip in the width direction are provided with teeth for engaging with the transmission gears.

[0012] By adopting this technical solution, the transmission gear arrangement enables efficient power transmission through the motor, achieving precise movement of the sample placement strip, thereby reducing manual intervention and improving the degree of automation. Furthermore, this meshing transmission method avoids slippage, ensuring reliable transmission and effectively reducing the risk of contact with other structures within the sample injection device during the injection process.

[0013] Preferably, there are two transfer guide rails to limit the direction of the sample placement strip, and the two transfer guide rails are perpendicular to the sample output guide rail. The sample placement strip does not turn during the transmission process on the sample output guide rail, the sample injection guide rail, and the transfer guide rail; the sample injection shell is located at the transfer guide rail and is provided with a transfer cylinder, and the transfer cylinder can push the sample placement strip on the transfer guide rail from the sample output guide rail to the sample injection guide rail.

[0014] By adopting the above technical solution, two transfer rails are set and perpendicular to the sample output rail, which effectively limits the transmission direction of the sample placement strip, ensuring that it remains stable and does not turn throughout the entire transmission path, thereby improving the transmission efficiency and ensuring that the direction of the sample placement strip entering the casing is consistent each time.

[0015] Preferably, the sample placement strip includes a strip body, a plurality of placement grooves are provided on the strip body along its length direction, and the strip body is provided with a lifting hole at the bottom of each placement groove, and a sample outlet notch is provided on one side of the strip body, the sample outlet notch is connected to the placement groove and the notch is semicircular, and the depth of the sample outlet notch is less than the depth of the placement groove; the unloading assembly includes an unloading conveyor belt, an unloading guide plate and an unloading lifting piece; the unloading conveyor belt is installed in the sample feeding shell, one end of the unloading conveyor belt is close to the sample outlet guide rail, and the top wall height of the unloading conveyor belt is lower than the bottom wall height of the sample outlet notch of the strip body located on the sample outlet guide rail; the unloading guide plate is installed at one end of the unloading conveyor belt close to the sample outlet guide rail, and the end of the unloading guide plate away from the unloading conveyor belt is located directly above the sample outlet guide rail, and the unloading guide plate can contact the sample located in the placement slot; the unloading lifting piece is installed at the bottom of the sample outlet guide rail to lift the sample and move it out from the sample outlet notch under the guidance of the unloading guide plate.

[0016] By adopting this technical solution, the placement slot on the strip is used to accommodate the sample, the lifting hole facilitates the unloading lift in the unloading assembly to lift the sample from the placement slot, and the sample removal notch design allows the sample to be smoothly removed from the side of the strip, avoiding sample jamming during removal. The unloading conveyor belt and unloading guide plate cooperate to ensure that the sample can be smoothly transferred from the sample placement strip to the unloading conveyor belt. The entire design effectively improves the efficiency of automated sample processing while reducing manual intervention, significantly reducing the impact on the internal structures of the sampling device during the injection process.

[0017] Preferably, the material unloading lifting member includes a lifting connecting frame and a lifting ball, one end of the lifting connecting frame is connected to the bottom of the sample outlet guide rail, and the end of the lifting connecting frame away from the sample outlet guide rail is connected to the lifting ball, and the lifting ball is elastically rotatably connected to the lifting connecting frame. The lifting ball can be partially inserted into the lifting hole under the action of elasticity to lift the sample to the height of the sample outlet notch.

[0018] By adopting this technical solution, the lifting ball can be partially inserted into the lifting hole under the action of elasticity, thereby achieving precise lifting of the sample and ensuring that the sample reaches the exact height of the sampling notch. This design effectively reduces manual intervention, improves the degree of automation, avoids the risk of contact during the sampling process, and further improves the operational safety and efficiency of the liquid chromatograph automatic sampling device.

[0019] Preferably, a material unloading auxiliary plate is elastically rotatably provided on one side of the material unloading conveyor belt close to the material unloading guide plate, and the material unloading auxiliary plate is located on the side of the material unloading guide plate close to the sample outlet, and the material unloading auxiliary plate and the material unloading guide plate form a gap for the sample to pass through.

[0020] By adopting the above technical solution, the unloading auxiliary plate and the unloading guide plate work together to form a gap for the sample to pass through, so that the sample can transition more smoothly to the unloading conveyor belt during the process of moving out of the sample outlet gap, effectively avoiding damage caused by collision after the sample is skewed, thereby improving the stability and reliability of the equipment operation.

[0021] Preferably, the loading assembly includes a loading conveyor belt and a loading pair of plates, the loading conveyor belt is installed in the sample injection shell, the loading conveyor belt and the unloading conveyor belt are arranged on the same side, one end of the loading conveyor belt is close to the sample output guide rail, and the top wall of the loading conveyor belt is higher than the bottom wall height of the sample output notch of the strip body located on the sample output guide rail; the loading pair of plates is installed on the loading conveyor belt to guide the sample from the sample output notch into the placement slot.

[0022] By adopting the above technical solutions, the placement of the loading conveyor belt and loading plate allows samples to be accurately guided from the sample outlet notch to the placement slot, ensuring that new samples are stably placed on the sample placement strip, thereby improving the level of automation and reducing the possibility of manual intervention. The positioning design of the loading conveyor belt ensures the height adaptability of samples, preventing samples from falling or tilting due to height differences. The loading plate further optimizes the sample introduction process, improving the efficiency and reliability of the entire sampling device.

[0023] Preferably, a placement rod is provided on the side of the casing away from the sample injection shell, and a positioning long slot is provided on the side of the placement rod near the sample injection port and the sample outlet, and the positioning long slot is opened in the horizontal direction, and placement notches are opened at both ends of the placement rod at the positioning long slot; a positioning block is provided at one end of the sample placement strip near the placement rod, and the positioning block can be inserted into the placement notch and the positioning long slot, and the positioning block can slide along the length direction of the positioning long slot, and an electrically controlled magnetic block is provided at the bottom of the placement notch near the sample injection port side, and the positioning block can be magnetically connected by the electrically controlled magnetic block; a controller is installed in the casing, and the electrically controlled magnetic block and the manipulator are both electrically connected to the controller, and the manipulator takes samples in the longitudinal direction of the sample placement strip for sampling, and when the manipulator puts the last sample on the sample placement strip back, it sends a sampling completion signal to the controller, and the controller controls the electrically controlled magnetic block to demagnetize after receiving the sampling completion signal; the guide component guides the sample placement strip to the transmission component after the electrically controlled magnetic block is demagnetized.

[0024] By adopting the above technical solution, by setting a placement rod, a positioning long mouth and a placement notch, and cooperating with the positioning block on the sample placement bar, the sample placement bar is ensured to be stably fixed in the casing, avoiding position displacement due to external interference, thereby reducing the touch of the internal structure of the sampling device; the magnetic connection between the electric control magnetic block and the positioning block is utilized to further enhance the reliability of the fixation of the sample placement bar, and prevent accidental movement during the sampling process of the manipulator; when the manipulator completes the sampling of the last sample and sends a sampling completion signal to the controller, the controller controls the electric control magnetic block to demagnetize, so that the sample placement bar enters the next work process, realizing automated management and efficient coordination, reducing the possibility of manual intervention and the risks it brings; the guide component intervenes in time after the electric control magnetic block is demagnetized, and guides and transports the sample placement bar that has completed sampling, thereby improving the operating efficiency and safety of the entire system; and realizing precise positioning and automated management of the sample placement bar in the casing.

[0025] Preferably, the guide assembly includes a guide cylinder and a pushing cylinder, the guide cylinder is installed on the inner wall of the casing to push the sample placement bar near the sample inlet toward the sample outlet; the pushing cylinder is installed in the casing, the pushing cylinder is arranged perpendicular to the placement rod, and the pushing cylinder is arranged on the side of the placement rod away from the sample placement area, and the pushing cylinder can pass through the placement gap to push the sample placement bar toward the sample outlet; the guide cylinder and the pushing cylinder are both electrically connected to the controller, and when the electric control magnetic block is demagnetized, it sends a release signal to the controller, and the controller controls the guide cylinder to start after receiving the release signal, and pushes the sample placement bar located at the sample inlet toward the sample outlet, and vacates the position at the sample inlet for the next sample placement bar containing the sample to be sampled to be introduced; after the guide cylinder completes pushing, it sends a guidance completion signal to the controller, and the controller controls the pushing cylinder to start after receiving the guidance completion signal, so as to be able to push the sample placement bar located on the axis of the sample outlet toward the transmission assembly.

[0026] By adopting the above technical solution, the coordinated use of the guide cylinder and the push cylinder ensures that the sample placement strip can be accurately moved from the sample inlet to the sample outlet and finally pushed to the transmission component. This design effectively reduces the need for manual intervention, improves the safety and efficiency of operation, and avoids the risk of touching the internal structure due to manual operation. In addition, the controller monitors the status of the electronically controlled magnetic block and accurately controls the movement of the cylinder, further improving the intelligence level and operational reliability of the system. Among them, the role of the guide cylinder is to preliminarily adjust the position of the sample placement strip, while the push cylinder is responsible for accurately sending it into the transmission component. The two work together to ensure the smooth progress of the entire process and realize automated control of the transfer process of the sample placement strip within the casing.

[0027] In summary, this application includes at least one of the following beneficial technical effects:

[0028] 1. The assembled samples are loaded by the loading assembly and loaded onto the empty sample placement strips at the transmission assembly. Even if the samples are not continuously placed on the sample placement strips, the sample placement strips still move under the transmission of the transmission assembly and finally enter the housing from the sampling port. The sample placement strips containing the samples to be sampled are placed in a row near the sampling area. The manipulator grabs the samples to be sampled in sequence and takes them to the sampling location for sampling. The samples that have been sampled are put back into the sample placement strips. After all the samples on the sample placement strips have been sampled, they are guided to the sample outlet by the guide assembly and transported by the transmission assembly. During the process, the unloading component unloads the sample from the sample placement strip after sampling, and the empty sample placement strip moves under the action of the transmission component and is loaded by the loading component. Repeating the above steps can realize automatic sampling; the injection port and the sample outlet are set in the injection shell, and the injection port is located between the sample outlet and the sampling area. With the design of the transmission component, the unloading component and the loading component, a complete sample flow path is formed, which improves the operation efficiency of the entire system; the existence of the guide component ensures that the sample placement strip can be accurately transferred to the transmission component after sampling is completed, further ensuring the smoothness and stability of the system operation;

[0029] 2. The sample placement slot on the strip is used to accommodate the sample. The lifting hole facilitates the lifting member in the unloading assembly to lift the sample from the placement slot. The sample removal notch design allows the sample to be smoothly removed from the side of the strip, avoiding sample jamming during removal. The unloading conveyor belt and unloading guide plate cooperate to ensure that the sample can be smoothly transferred from the sample placement strip to the unloading conveyor belt. The entire design effectively improves the efficiency of automated sample processing while reducing manual intervention, significantly reducing the impact on the internal structure of the sampling device during the injection process.

[0030] 3. By setting the placement rod, positioning long mouth and placement notch, and cooperating with the positioning block on the sample placement bar, the sample placement bar is ensured to be stably fixed in the casing, avoiding position displacement due to external interference, thereby reducing the touch of the internal structure of the sampling device; the magnetic connection between the electric control magnetic block and the positioning block is used to further enhance the reliability of the fixation of the sample placement bar, and prevent accidental movement during the sampling process of the manipulator; when the manipulator completes the sampling of the last sample and sends a sampling completion signal to the controller, the controller controls the electric control magnetic block to demagnetize, so that the sample placement bar enters the next work process, realizing automated management and efficient coordination, reducing the possibility of manual intervention and the risks it brings; the guide component intervenes in time after the electric control magnetic block is demagnetized, and guides and transports the sample placement bar that has completed sampling, thereby improving the operating efficiency and safety of the entire system; and realizing precise positioning and automated management of the sample placement bar in the casing. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1It is a structural schematic diagram of an automatic sampling device of a liquid chromatograph in an embodiment of the present application.

[0032] Figure 2 It is a schematic diagram used to illustrate the internal structure of the casing and the injection shell in the embodiment of the present application.

[0033] Figure 3 yes Figure 2 A is an enlarged schematic diagram.

[0034] Figure 4 It is a cross-sectional view used to illustrate the structure of the sample placement strip in the embodiment of the present application.

[0035] Figure 5 It is an exploded view used to illustrate the sliding relationship between the positioning block and the positioning rod in the embodiment of the present application.

[0036] Explanation of reference numerals: 1, housing; 11, sample placement area; 12, sampling area; 13, placement rod; 131, positioning long opening; 132, placement notch; 133, electric control magnetic block; 2, sample placement bar; 21, bar body; 22, placement groove; 23, lifting hole; 24, sample outlet notch; 25, positioning block; 3, injection housing; 31, injection port; 32, sample outlet; 4, transmission component; 41, sample outlet guide rail; 42, Feeding guide rail; 43. Transfer guide rail; 431. Transfer cylinder; 44. Transmission part; 441. Transmission gear; 5. Unloading assembly; 51. Unloading conveyor belt; 52. Unloading guide plate; 53. Unloading lifting part; 531. Lifting connecting frame; 532. Lifting ball; 54. Unloading auxiliary plate; 6. Loading assembly; 61. Loading conveyor belt; 62. Loading plate; 7. Guide assembly; 71. Guide cylinder; 72. Push cylinder. DETAILED DESCRIPTION

[0037] The following is combined with Figure 1-5 This application is described in further detail.

[0038] The present application discloses an automatic sampling device for a liquid chromatograph. Figure 1 and Figure 2 The automatic sample injection device of the liquid chromatograph includes a housing 1, a sample placement area 11 disposed within the housing 1, a sampling area 12 disposed to one side of the sample placement area 11, and a plurality of rows of sample placement strips 2 disposed within the sample placement area 11. The plurality of sample placement strips 2 are sequentially arranged along the sampling area 12 toward the sample placement area 11. A guide assembly 7 is disposed within the housing 1.

[0039] The casing 1 is provided with an injection shell 3 on the same side of the sample placement area 11 and the area area, and the injection shell 3 is bolted or integrally formed on the side of the casing 1; the injection port 31 and the outlet port 32 are provided on the side of the casing 1 close to the casing 1, and the injection port 31 is located between the outlet port 32 and the sampling area 12; a transmission component 4 is provided in the injection shell 3, and a discharge component 5 is provided on the side of the injection shell 3 located on the transmission component 4, and a loading component 6 is provided on the side of the injection shell 3 located on the transmission component 4.

[0040] The assembled samples are loaded by the loading component 6 and the samples to be sampled are loaded onto the empty sample placement strip 2 at the transmission component 4. Even if the samples are not continuously placed on the sample placement strip 2, the sample placement strip 2 still moves under the transmission of the transmission component 4 and finally enters the housing 1 through the sampling port 31; the sample placement strip 2 containing the samples to be sampled is in a row close to the sampling area 12, and the robot grabs the samples to be sampled in sequence to the sampling area for sampling, and the sampled samples are put back into the sample placement strip 2; after all the samples on the sample placement strip 2 are sampled, they are guided to the sample outlet 32 ​​by the guide component 7 and transmitted by the transmission component 4. During the transmission process, the sampled samples are unloaded from the sample placement strip 2 by the unloading component 5, and the empty sample placement strip 2 moves under the action of the transmission component 4 and is loaded by the loading component 6. The above steps are repeated to realize automatic sampling.

[0041] An injection port 31 and an outlet port 32 are provided in the injection shell 3, and the injection port 31 is located between the outlet port 32 and the sampling area 12. Combined with the design of the transmission component 4, the unloading component 5 and the loading component 6, a complete sample flow path is formed, thereby improving the operating efficiency of the entire system; the presence of the guide component 7 ensures that after the sampling is completed, the sample placement strip 2 can be accurately transferred to the transmission component 4, further ensuring the smoothness and stability of the system operation.

[0042] Reference Figure 2 and Figure 3The transmission component 4 includes a sample outlet guide rail 41, a sample injection guide rail 42, and a transfer guide rail 43. The sample outlet guide rail 41 and the sample injection guide rail 42 are parallel and have the same length. One end of the sample outlet guide rail 41 is set at the sample outlet 32, and one end of the sample injection guide rail 42 is set at the sample injection port 31. One end of the transfer guide rail 43 is connected to the end of the sample outlet guide rail 41 away from the sample outlet 32, and the other end is connected to the end of the sample injection guide rail 42 away from the sample injection port 31. The sample outlet guide rail 41 and the sample injection guide rail 42 are close to the transfer guide rail 43. Tilt downward; at this time, the sample discharge guide rail 41, the sample injection guide rail 42, and the transfer guide rail 43 form a concave track. In this embodiment, in order to improve the transmission stability of the sample placement bar 2, a guide wheel that serves as a limit and support is installed at the bottom of the sample placement bar 2. When the sample placement bar 2 moves on the sample injection guide rail 42 and the sample discharge guide rail 41, the sample placement bar 2 can move stably under the guidance of the guide wheel. At this time, the length direction of the sample placement bar 2 is parallel to the running direction of the sample injection guide rail 42 and the sample discharge guide rail 41.

[0043] The transfer rail 43 is perpendicular to both the sample inlet rail 42 and the sample outlet rail 41. When the sample placement bar 2 moves from the sample outlet rail 41 to the transfer rail 43, the sample placement bar 2 does not rotate. At this time, the guide wheel reaches the end of the sample outlet rail 41 and aligns with the transfer rail 43, allowing it to enter the transfer rail 43. When the sample placement bar 2 enters the transfer rail 43, the sample placement bar 2 remains perpendicular to the transfer rail 43. When the sample placement bar 2 moves along the transfer rail 43 to the end, the guide wheel of the sample placement bar 2 reaches the end of the transfer rail 43 and aligns with the sample inlet rail 42, allowing it to enter the sample inlet rail 42. In other words, when the sample placement bar 2 moves on the concave guide rail, it always maintains the same direction.

[0044] A transmission member 44 is provided on one side of each of the sample outlet rail 41 and the sample inlet rail 42, for transporting the sample placement strip 2 along the sample outlet rail 41 and the sample inlet rail 42. The transmission member 44 comprises a plurality of transmission gears 441. The transmission gears 441 on the sample outlet rail 41 are rotatably connected to the end of the sample outlet rail 41 near the sample outlet port 32, and the transmission gears 441 on the sample outlet rail 41 are disposed between the sample outlet rail 41 and the sample inlet rail 42. The transmission gears 441 on the sample inlet rail 42 are rotatably connected to the end of the sample inlet rail 42 away from the sample inlet port 31. In this embodiment, the transmission gears 441 on both the sample outlet rail 41 and the sample inlet rail 42 are externally connected to motors.

[0045] Teeth are provided at the bottom of the side wall in the width direction of the sample placement bar 2 to facilitate engagement with the transmission gear 441 ; the sample placement bar 2 moves during the rotation of the transmission gear 441 .

[0046] Reference Figure 2 and Figure 3In the present application, the sample injection shell 3 is provided with a transfer cylinder 431 at the transfer guide rail 43, and the transfer cylinder 431 can push the sample placement strip 2 on the transfer guide rail 43 from the sample outlet guide rail 41 to the sample injection guide rail 42; the transfer guide rail 43 is perpendicular to the sample outlet guide rail 41.

[0047] The sample placement bar 2 enters the sample outlet guide rail 41 from the sample outlet 32 ​​and engages with the transmission gear 441 on the sample outlet guide rail 41. Under the rotation of the transmission gear 441 on the sample outlet guide rail 41, the sample placement bar 2 moves along the length direction of the sample outlet guide rail 41. When the guide wheel on the sample placement bar 2 reaches the end of the sample outlet guide rail 41, the guide wheel is just aligned with the transfer guide rail 43; at this time, the transfer cylinder 431 starts to push the sample placement bar 2 aligned with the transfer guide rail 43 toward the direction of the injection guide rail 42 until the sample placement bar 2 engages with the transmission gear 441 located at the injection guide rail 42. Under the rotation of the transmission gear 441, the sample placement bar 2 moves along the direction of the injection guide rail 42, and the guide wheel on the sample placement bar 2 enters the injection guide rail 42 from the transfer guide rail 43 and moves along the length direction of the injection guide rail 42.

[0048] Reference Figure 3 and 4 In this embodiment, the sample placement strip 2 is a rectangular long strip 21, and a plurality of placement grooves 22 are provided on the strip 21 along its length direction. A lifting hole 23 is provided at the bottom of each placement groove 22 of the strip 21, and a sample outlet notch 24 is provided on one side of the strip 21. The sample outlet notch 24 is connected to the placement groove 22 and the notch is a semi-arc. The depth of the sample outlet notch 24 is less than the depth of the placement groove 22; when the sample placement strip 2 of the above structure moves on the sample outlet guide rail 41, the sample outlet notch 24 always points away from the direction of the sample introduction guide rail 42 to facilitate the unloading component 5 to unload the sample in the placement groove 22.

[0049] The unloading assembly 5 includes an unloading conveyor belt 51, which is installed in the sample injection shell 3 and is perpendicular to the sample discharge guide rail 41. One end of the unloading conveyor belt 51 is close to the sample discharge guide rail 41, and the sample discharge guide rail 41 is located between the unloading conveyor belt 51 and the sample injection guide rail 42. The top wall height of the unloading conveyor belt 51 is lower than the bottom wall height of the sample discharge notch 24 of the strip body 21 located on the sample discharge guide rail 41; when the sample placement strip 2 moves to the unloading conveyor belt 51 under the action of the transmission gear 441, the sample discharge notch 24 is opposite to the unloading conveyor belt 51.

[0050] A discharge guide plate 52 is mounted on the end of the discharge conveyor 51 near the sample outlet rail 41. The end of the discharge guide plate 52, away from the discharge conveyor 51, is located directly above the sample outlet rail 41. The discharge guide plate 52 is capable of contacting the sample within the placement slot 22. A discharge auxiliary plate 54 is mounted on the side of the discharge conveyor 51 near the discharge guide plate 52, which is elastically rotated by a torsion spring. The discharge auxiliary plate 54 is located on the side of the discharge guide plate 52 near the sample outlet 32, and the discharge auxiliary plate 54 and the discharge guide plate 52 form a gap for the sample to pass through.

[0051] A sample discharging and lifting member 53 is mounted at the bottom of the sample discharging guide rail 41 to lift the sample. The member comprises a lifting connection frame 531, one end of which is connected to the bottom of the sample discharging guide rail 41. The end of the lifting connection frame 531, away from the sample discharging guide rail 41, is connected to a lifting ball 532. The lifting ball 532 is elastically rotatably connected to the lifting connection frame 531 via a torsion spring. The diameter of the lifting ball 532 is smaller than the inner diameter of the lifting hole 23. Under the action of the spring, the lifting ball 532 can be partially inserted into the lifting hole 23 to lift the sample to the height of the sample discharging notch 24.

[0052] When the sample placement bar 2 moves to the unloading conveyor belt 51 under the action of the transmission gear 441 and the lifting ball 532 is aligned with the placement slot 22, the lifting ball 532 is inserted into the placement slot 22 under the action of the torsion spring, and the sample in the placement slot 22 that has been sampled is lifted to the position of the sample outlet notch 24. At this time, the sample just contacts the unloading guide plate 52. The sample placement bar 2 continues to move under the action of the transmission gear 441 and the sample is limited by the unloading guide plate 52. Therefore, the sample that has been sampled is guided by the unloading guide plate 52 and is guided out of the sample outlet notch 24. It moves smoothly to the unloading conveyor belt 51 with the assistance of the unloading auxiliary plate 54 and is finally transmitted out through the unloading conveyor belt 51.

[0053] After the sample placement strip 2 with the sample that has been sampled passes through the unloading guide plate 52, the sample that has been sampled is transported by the unloading conveyor belt 51. At this time, the placement slot 22 of the sample placement strip 2 is empty, and the sample placement strip 2 continues to move toward the transfer guide rail 43 under the action of the transmission gear 441. During the movement, the sample placement strip 2 passes through the loading component 6 and loads the sample to be sampled at the loading component 6.

[0054] Reference Figure 3The loading assembly 6 includes a loading conveyor belt 61, which is installed within the sample injection housing 3. The loading conveyor belt 61 is located on the same side as the unloading conveyor belt 51 and is perpendicular to the sample discharge guide rail 41, with one end of the loading conveyor belt 61 adjacent to the sample discharge guide rail 41. The top wall of the loading conveyor belt 61 is higher than the bottom wall of the sample discharge notch 24 located in the strip body 21 of the sample discharge guide rod, and the top wall of the loading conveyor belt 61 is lower than the top of the placement slot 22. A loading counterplate 62 is installed at the end of the loading conveyor belt 61 adjacent to the sample discharge guide rail 41. The loading counterplate 62 guides the sample to be sampled to the sample discharge notch 24 and ultimately into the placement slot 22 of the sample placement strip 2. To improve loading accuracy, the distance between the inner wall of the placement slot 22 and the end of the loading conveyor belt 61 is kept small.

[0055] Reference Figure 4 and Figure 5 After the sample placement strip 2 is loaded, it is transported by the transfer guide 43 and the sample injection guide 42 and enters the housing 1 through the injection port 31. A placement rod 13 is provided on the side of the housing 1 away from the injection housing 3. The length of the placement rod 13 is set in the direction from the injection port 31 to the sample outlet 32. That is, when the sample placement strip 2 enters the housing 1 through the injection port 31, the sample placement strip 2 is perpendicular to the placement rod 13.

[0056] A positioning slot 131 is defined on one side of the placement rod 13, near the sample inlet 31 and the sample outlet 32. The vertical cross-section of the positioning slot 131 is a combination of a circle and a rectangular strip, with the circle's diameter being greater than the rectangle's width. The positioning slot 131 extends horizontally, and placement notches 132, communicating with the positioning slot 131, are defined at both ends of the placement rod 13. A positioning block 25 is integrally formed on the end of the sample placement strip 2, near the placement rod 13. The positioning block 25 can be inserted into the placement notch 132 and the positioning slot 131, and can slide along the length of the positioning slot 131.

[0057] In order to improve the accuracy of the robot arm when taking samples in the sample placement strip 2, an electrically controlled magnetic block 133 is provided at the bottom of the placement notch 132 near the side of the injection port 31. In this embodiment, part of the electrically controlled magnetic block 133 is in the placement notch 132, and part of it is in the positioning long opening 131. The metal material embedded in the positioning block 25 can be magnetically connected by the electrically controlled magnetic block 133.

[0058] A controller is installed in the housing 1. In this embodiment, the controller is a PLC controller. The electric control magnetic block 133 and the manipulator are electrically connected to the controller. The sample placement strip 2 with the sample to be sampled enters the housing 1 through the transmission gear 441 through the injection port 31. The positioning block 25 on the sample placement strip 2 of the sample to be sampled is first inserted into the placement notch 132. At this time, the electric control magnetic block 133 is energized, and the electric control magnetic block 133 generates magnetic attraction to the positioning block 25. Since a part of the electric control magnetic block 133 is in the placement notch 132 and a part is in the positioning long opening 131, so the sample placement bar 2 of the sample to be sampled moves under the action of the electric-controlled magnetic block 133, and a part of the positioning block 25 enters the positioning long mouth 131. At this time, the positioning long mouth 131 can limit the positioning block 25 and limit the skewness of the sample placement bar 2; the manipulator takes the samples in the order of the length direction of the sample placement bar 2 for sampling. When the manipulator puts the last sample on the sample placement bar 2 back, it sends a sampling completion signal to the controller. After receiving the sampling completion signal, the controller controls the electric-controlled magnetic block 133 to release the magnetism.

[0059] In the above structure, a contact sensor or a distance sensor can be further provided in the housing 1 to determine whether the positioning block 25 on the sample placement strip 2 is inserted into the placement notch 132 . The above sensor can also be electrically connected to the controller.

[0060] When the electrically controlled magnetic block 133 is demagnetized, the sample placement strip containing the sample that has been sampled can be moved under the action of the guide assembly 7, that is, the positioning block 25 can move along the positioning slot 131; the guide assembly 7 includes a guide cylinder 71, which is mounted on the inner wall of the housing 1 and is used to push the sample placement strip 2 near the sample inlet 31 toward the sample outlet 32. The guide cylinder 71 is also electrically connected to the controller. When the electrically controlled magnetic block 133 is demagnetized, it sends a release signal to the controller. After receiving the release signal, the controller controls the guide cylinder 71 to start, pushing the sample placement strip 2 containing the sample that has been sampled at the sample inlet 31 toward the sample outlet 32, thereby clearing the space at the sample inlet 31 for the next sample placement strip 2 containing the sample to be sampled.

[0061] Under the action of the guide cylinder 71, the sample placement strip 2 with the sample that has been sampled moves to the placement notch 132 of the placement rod 13 near the sample outlet 32. At this time, the positioning block 25 is completely located in the placement notch 132. A push cylinder 72 is also installed in the housing 1. The push cylinder 72 is arranged perpendicular to the placement rod 13 and is arranged on the side of the placement rod 13 away from the sample placement area 11. The push cylinder 72 can pass through the placement notch 132 to push the sample placement strip 2 toward the sample outlet 32. The push cylinder 72 is also electrically connected to the controller. After the guide cylinder 71 completes pushing, it sends a guidance completion signal to the controller. After receiving the guidance completion signal, the controller controls the push cylinder 72 to start, so as to be able to move the sample placement strip 2 located on the axis of the sample outlet 32 ​​toward the sample outlet guide rail 41. The push cylinder 72 pushes the sample placement strip 2 until the sample placement strip 2 is engaged with the transmission gear 441.

[0062] The implementation principle of the automatic sampling device of a liquid chromatograph in an embodiment of the present application is as follows: the assembled sample is loaded by the loading conveyor belt 61, and the sample to be sampled is loaded onto the placement slot 22 of the empty sample placement strip 2 by means of the guide at the sample output guide rail 41. Even if the sample is not placed continuously on the sample placement strip 2, that is, there is an empty placement slot 22 on the sample placement strip 2, the sample placement strip 2 still moves under the transmission of the sample output guide rail 41, and finally enters the housing 1 from the sample inlet 31 via the transfer guide rail 43 and the sample injection guide rail 42.

[0063] The positioning block 25 on the sample placement bar 2 of the sample to be sampled is first inserted into the placement gap 132. At this time, the electric-controlled magnetic block 133 is energized, and the electric-controlled magnetic block 133 generates magnetic attraction to the positioning block 25. The sample placement bar 2 of the sample to be sampled moves under the action of the electric-controlled magnetic block 133. A part of the positioning block 25 enters the positioning long opening 131. The manipulator takes the samples in the longitudinal direction of the sample placement bar 2 for sampling. When the manipulator puts the last sample on the sample placement bar 2 back, it sends a sampling completion signal to the controller. After receiving the sampling completion signal, the controller controls the electric-controlled magnetic block 133 to demagnetize.

[0064] When the electrically controlled magnetic block 133 is demagnetized, it sends a release signal to the controller. Upon receiving the release signal, the controller activates the guide cylinder 71, pushing the sample placement bar 2 with the sample already drawn from it, located at the sample inlet 31, toward the sample outlet 32, freeing up space at the sample inlet 31 for the next sample placement bar 2 containing the sample to be drawn. After completing the push, the guide cylinder 71 sends a guide completion signal to the controller. Upon receiving the guide completion signal, the controller activates the push cylinder 72, moving the sample placement bar 2, located on the axis of the sample outlet 32, toward the sample outlet guide rail 41. The push cylinder 72 pushes the sample placement bar 2 until it engages with the transmission gear 441.

[0065] During the transmission process of the sample discharge guide rail 41, when the sample placement bar 2 moves to the unloading conveyor belt 51 under the action of the transmission gear 441 and the lifting ball 532 is aligned with the placement slot 22, the lifting ball 532 is inserted into the placement slot 22 under the action of the torsion spring, and the sample in the placement slot 22 that has been sampled is lifted to the position of the sample discharge notch 24. At this time, the sample just contacts the unloading guide plate 52, and the sample placement bar 2 continues to move under the action of the transmission gear 441 and the sample is limited by the unloading guide plate 52. Therefore, the sample that has been sampled is guided by the unloading guide plate 52 and is guided out of the sample discharge notch 24. It is smoothly moved to the unloading conveyor belt 51 with the assistance of the unloading auxiliary plate 54 and finally transmitted through the unloading conveyor belt 51.

[0066] At this point, the sample placement slot 22 of the sample placement strip 2 is empty. The sample placement strip 2 continues to move toward the transfer guide 43 under the action of the transmission gear 441. During this movement, the sample placement strip 2 passes over the loading conveyor 61 and is loaded with the sample to be sampled. Repeating this operation achieves automatic sampling.

[0067] An injection port 31 and an outlet port 32 are provided in the injection shell 3, and the injection port 31 is located between the outlet port 32 and the sampling area 12. Combined with the design of the transmission component 4, the unloading component 5 and the loading component 6, a complete sample flow path is formed, thereby improving the operating efficiency of the entire system; the presence of the guide component 7 ensures that after the sampling is completed, the sample placement strip 2 can be accurately transferred to the transmission component 4, further ensuring the smoothness and stability of the system operation.

[0068] The above are all preferred embodiments of the present application, and are not intended to limit the scope of protection of the present application. Therefore, any equivalent changes made based on the structure, shape, and principle of the present application should be included in the scope of protection of the present application.

Claims

1. An automatic sample injection device for a liquid chromatograph, comprising a housing (1), wherein a sample placement area (11) is provided in the housing (1), and characterized in that: A plurality of rows of sample placement strips (2) are provided in the sample placement area (11) away from the sampling area (12); a sample injection shell (3) is provided on one side of the housing (1); a sample injection port (31) and a sample outlet (32) are provided on the side of the sample injection shell (3) close to the housing (1); the sample injection port (31) is located between the sample outlet (32) and the sampling area (12); a transmission component (4) for transporting the sample placement strips (2) is provided in the sample injection shell (3); a discharging component (5) for removing the sample from the sample placement strips (2) after sampling is completed is also provided in the sample injection shell (3); a loading component (6) for placing a new sample on the empty sample placement strips (2) is also provided in the sample injection shell (3); the housing ( 1) is provided with a guide component (7) for transferring the sample placement strip (2) after sample sampling to the transmission component (4); the transmission component (4) includes a sample discharge guide rail (41), a sample injection guide rail (42), a transfer guide rail (43) and a transmission member (44), the sample discharge guide rail (41) and the sample injection guide rail (42) are parallel, one end of the sample discharge guide rail (41) is arranged at the sample discharge port (32), one end of the sample injection guide rail (42) is arranged at the sample injection port (31), one end of the transfer guide rail (43) is connected to the end of the sample discharge guide rail (41) away from the sample discharge port (32), and the other end is connected to the end of the sample injection guide rail (42) away from the sample injection port (31); one side of each of the sample discharge guide rail (41) and the sample injection guide rail (42) is provided with a transfer member (44). The transport member (44) is used to transport the sample placement strip (2) to move on the sample discharge guide rail (41) and the sample feed guide rail (42); the sample placement strip (2) includes a strip body (21), a plurality of placement grooves (22) are provided on the strip body (21) along its length direction, the strip body (21) is provided with a lifting hole (23) at the bottom of each placement groove (22), a sample discharge notch (24) is provided on one side of the strip body (21), the sample discharge notch (24) is connected to the placement groove (22) and the notch is semicircular, and the depth of the sample discharge notch (24) is less than the depth of the placement groove (22); the blanking assembly (5) includes a blanking conveyor belt (51), a blanking guide plate (52) and a blanking lifting member (53); the blanking conveyor belt (51) ) is installed in the sample feeding shell (3), one end of the unloading conveyor belt (51) is close to the sample discharging guide rail (41), and the top wall height of the unloading conveyor belt (51) is lower than the bottom wall height of the sample discharging notch (24) of the strip body (21) located on the sample discharging guide rail (41); the unloading guide plate (52) is installed at one end of the unloading conveyor belt (51) close to the sample discharging guide rail (41), and the end of the unloading guide plate (52) away from the unloading conveyor belt (51) is located directly above the sample discharging guide rail (41), and the unloading guide plate (52) can contact the sample located in the placement groove (22); the unloading lifting member (53) is installed at the bottom of the sample discharging guide rail (41) to lift the sample and move it out of the sample discharging notch (24) under the guidance of the unloading guide plate (52);The material discharging and lifting member (53) includes a lifting connection frame (531) and a lifting ball (532), one end of the lifting connection frame (531) is connected to the bottom of the sample discharging guide rail (41), and the end of the lifting connection frame (531) away from the sample discharging guide rail (41) is connected to the lifting ball (532), and the lifting ball (532) is elastically rotatably connected to the lifting connection frame (531). The lifting ball (532) can be partially inserted into the lifting hole (23) under the action of elasticity to lift the sample to the height of the sample discharging notch (24); the side of the material discharging conveyor belt (51) close to the material discharging guide plate (52) is elastically The rotary device is provided with a material unloading auxiliary plate (54), the material unloading auxiliary plate (54) being located on a side of the material unloading guide plate (52) close to the sample outlet (32), and the material unloading auxiliary plate (54) and the material unloading guide plate (52) forming a gap for the sample to pass through; after all samples on the sample placement strip (2) are sampled, they are guided to the sample outlet (32) by the guide component (7) and transported by the transmission component (4); during the transport process, the sample unloading component (5) unloads the sample from the sample placement strip (2), and the empty sample placement strip (2) moves under the action of the transmission component (4) and is loaded by the loading component (6).

2. The automatic sample injection device for liquid chromatograph according to claim 1, characterized in that: The transmission member (44) is a transmission gear (441), and the transmission gear (441) at the sample outlet guide rail (41) is rotatably connected to one end of the sample outlet guide rail (41) close to the sample outlet port (32), and the transmission gear (441) at the sample injection guide rail (42) is rotatably connected to one end of the sample injection guide rail (42) away from the sample injection port (31); one of the transmission gears (441) is externally connected to a motor, and the two transmission gears (441) are connected via a transmission structure; the side wall of the sample placement strip (2) in the width direction is provided with teeth for engaging with the transmission gear (441).

3. The automatic sample injection device for liquid chromatograph according to claim 2, characterized in that: There are two transfer rails (43) to define the direction of the sample placement strip (2). The two transfer rails (43) are perpendicular to the sample outlet rail (41). The sample placement strip (2) does not turn during the process of being transported on the sample outlet rail (41), the sample injection rail (42), and the transfer rail (43). The sample injection housing (3) is provided with a transfer cylinder (431) at the transfer rail (43). The transfer cylinder (431) can push the sample placement strip (2) on the transfer rail (43) from the sample outlet rail (41) to the sample injection rail (42).

4. The automatic sample injection device for liquid chromatograph according to claim 1, characterized in that: The loading assembly (6) comprises a loading conveyor belt (61) and a loading pair plate (62). The loading conveyor belt (61) is installed in the sample injection shell (3). The loading conveyor belt (61) and the unloading conveyor belt (51) are arranged on the same side. One end of the loading conveyor belt (61) is close to the sample output guide rail (41). The top wall of the loading conveyor belt (61) is higher than the bottom wall height of the sample output notch (24) of the strip body (21) located on the sample output guide rail (41). The loading pair plate (62) is installed on the loading conveyor belt (61) to guide the sample from the sample output notch (24) into the placement groove (22).

5. The automatic sample injection device for liquid chromatograph according to claim 1, characterized in that: A placement rod (13) is provided on a side of the housing (1) away from the injection housing (3), and a positioning long opening (131) is provided on a side of the placement rod (13) close to the injection port (31) and the sample outlet (32), and the positioning long opening (131) is opened in a horizontal direction. The placement rod (13) is provided with placement notches (132) at both ends of the positioning long opening (131); a positioning block (25) is provided on one end of the sample placement strip (2) close to the placement rod (13), and the positioning block (25) can be inserted into the placement notch (132) and the positioning long opening (131), and the positioning block (25) can slide along the length direction of the positioning long opening (131), and is close to the injection port (31). An electrically controlled magnetic block (133) is provided at the bottom of the placement notch (132), and the positioning block (25) can be magnetically connected to the electrically controlled magnetic block (133); a controller is installed in the housing (1), and the electrically controlled magnetic block (133) and the manipulator are both electrically connected to the controller, and the manipulator takes samples in the longitudinal direction of the sample placement bar (2) for sampling. When the manipulator puts the last sample on the sample placement bar (2) back, it sends a sampling completion signal to the controller, and after receiving the sampling completion signal, the controller controls the electrically controlled magnetic block (133) to demagnetize; and the guide component (7) guides the sample placement bar (2) to the transmission component (4) after the electrically controlled magnetic block (133) is demagnetized.

6. The automatic sample injection device for liquid chromatograph according to claim 5, characterized in that: The guide assembly (7) comprises a guide cylinder (71) and a push cylinder (72), wherein the guide cylinder (71) is mounted on the inner wall of the housing (1) to push the sample placement strip (2) near the sample inlet (31) toward the sample outlet (32); the push cylinder (72) is mounted in the housing (1), the push cylinder (72) is vertically arranged with respect to the placement rod (13), and the push cylinder (72) is arranged on the side of the placement rod (13) away from the sample placement area (11), and the push cylinder (72) can pass through the placement notch (132) to push the sample placement strip (2) toward the sample outlet (32); the guide cylinder (71) and the push cylinder (72) are arranged in a vertical direction with respect to the placement rod (13), and the push cylinder (72) is arranged on the side of the placement rod (13) away from the sample placement area (11). ) are electrically connected to the controller. When the electric-controlled magnetic block (133) is demagnetized, it sends a release signal to the controller. After receiving the release signal, the controller controls the guide cylinder (71) to start, and pushes the sample placement bar (2) located at the sample inlet (31) toward the sample outlet (32), so as to free up the position at the sample inlet (31) for the next sample placement bar (2) containing the sample to be sampled to be introduced. After the guide cylinder (71) completes the pushing, it sends a guide completion signal to the controller. After receiving the guide completion signal, the controller controls the push cylinder (72) to start, so as to be able to push the sample placement bar (2) located on the axis of the sample outlet (32) toward the transmission component (4).

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