Composition having excellent skin roughness improving effect

Abstract

Disclosed is a composition having an excellent skin roughness improving effect. The composition has an excellent skin roughness improving effect, has a pH in a specific range, and contains a specific polymer.

Description

[0001] CROSS-REFERENCE TO RELATED APPLICATIONS

[0002] This patent application claims priority based on Japanese Patent Application No. 2022-212586 (filing date: December 28, 2022). The entire disclosure of the prior patent application is incorporated herein by reference as part of this specification. TECHNICAL FIELD

[0003] The present invention relates to a composition having an excellent effect of improving skin roughness. BACKGROUND ART

[0004] With environmental changes and dietary diversification, the deterioration of skin conditions such as sensitive skin and atopic dermatitis has become increasingly serious. As methods for improving them, various methods have been considered. As one of them, there is a method of achieving improvement by applying a composition having an effect of improving such skin conditions to a subject. As such a composition, various products such as cosmetics having a moisturizing effect and an effect of improving skin roughness have been developed.

[0005] For example, Patent Document 1 discloses a skin external preparation for suppressing stickiness, which is characterized by containing at least one or more of glucosaminoglycans and a polymer of 2-methacryloyloxyethyl phosphorylcholine. Glucosaminoglycans such as hyaluronic acid and chondroitin sulfate, polyhydric alcohols such as sorbitol, ethylene glycol, and glycerol, organic acid salts such as sodium pyrrolidone carboxylate and sodium lactate, and proteins such as collagen and elastin are all components used as moisturizing agents in the skin.

[0006] In addition, depending on the individual, at various stages of their life, dark and / or darker-colored spots that give an uneven appearance to the skin, especially on the hands, sometimes appear. When seeking to improve such spots, an operation of applying a composition having an effect of improving skin spots to a subject is also performed. As such a composition, products such as cosmetics having an effect of improving spots have been developed.

[0007] For example, Patent Document 2 discloses a cosmetic and / or dermatological composition containing a cosmetically acceptable acidic aqueous medium and at least one crosslinked poly(2-acrylamido-2-methylpropanesulfonic acid) polymer neutralized by at least 90%. As the organic active substances contained in such an acidic aqueous medium, for example, kojic acid, caffeic acid, salicylic acid, and their derivatives can be used. These components are usually components used in the treatment of spots.

[0008] In this way, various studies have been conducted on compositions having the effect of improving skin condition. However, for example, when the deterioration of skin condition occurs unevenly, for improving the part with a large degree of deterioration, relatively intensive care is required. On the other hand, for improving the part with a small degree of deterioration, relatively less care is sufficient. However, there are usually problems such as: the part coated with the topical composition is uniformly cared for, and appropriate care corresponding to the degree of deterioration is not carried out, and occasionally it can be seen that the effect is not necessarily sufficient.

[0009] Prior art documents

[0010] Patent documents

[0011] Patent Document 1: Japanese Patent Laid-Open No. 9-052848

[0012] Patent Document 2: Japanese Patent Laid-Open No. 10-067616 Summary of the invention

[0013] The present inventors have found that a composition having a pH in a specific range and containing a specific polymer has an excellent effect of improving skin roughness. The present invention is based on this finding.

[0014] Therefore, the present invention provides a composition having an excellent effect of improving skin roughness, having a pH in a specific range, and containing a specific polymer.

[0015] According to the present invention, the following technical solutions are provided.

[0016] (1) A composition comprising:

[0017] (A) A microgel; and

[0018] (B) A copolymer of 2-methacryloyloxyethyl phosphorylcholine and butyl methacrylate,

[0019] The foregoing component (A) contains (a1) a polymer having at least one group selected from a sulfonic acid group and a sulfate group, and

[0020] The foregoing component (A) satisfies: (a2) it has an irregular shape in the composition,

[0021] The pH of the composition is 4.0 to 5.0.

[0022] (2) The composition according to (1), wherein the polymer in the foregoing (a1) is a copolymer having a compound having at least one group selected from a sulfonic acid group and a sulfate group as a monomer.

[0023] (3) The composition according to (1) or (2), wherein the monomer in the foregoing (a1) is acryloyldimethyltaurine ammonium.

[0024] (4) The composition according to any one of (1) to (3), wherein the copolymer in the aforementioned (a1) is one or more selected from the group consisting of ammonium acryloyldimethyltaurate / behenyl alcohol polyether-25 methacrylate cross-linked polymer and (ammonium acryloyldimethyltaurate / vinylpyrrolidone) copolymer.

[0025] (5) The composition according to any one of (1) to (4), wherein the average particle diameter of the aforementioned component (A) in the water-swelled state is 2 to 50 μm.

[0026] (6) The composition according to any one of (1) to (5), wherein when the compounding amount of the component (a1) in the aforementioned composition is set as MA and the compounding amount of the component (B) is set as MB, the MA / MB ratio is 1.0 or more.

[0027] (7) The composition according to any one of (1) to (6), further comprising (C) a polyol.

[0028] (8) The composition according to (7), wherein the aforementioned component (C) is one or more selected from the group consisting of glycerin and polyglycerin.

[0029] (9) The composition according to (7) or (8), wherein the aforementioned component (C) further comprises one or more selected from the group consisting of dihydric alcohols having 3 to 6 carbon atoms.

[0030] (10) The composition according to any one of (1) to (9) is in the form of a solution, suspension, dispersion, emulsion, cream, ointment, gel, lotion, foam, paste or spray.

[0031] (11) The composition according to any one of (1) to (10) is a cosmetic composition.

[0032] (12) A composition comprising (A) a microgel,

[0033] The aforementioned component (A) comprises (a1) a polymer having one or more groups selected from a sulfonic acid group and a sulfate group,

[0034] comprises (a3) a cationic polymer, and

[0035] The aforementioned component (A) satisfies: (a4) the average particle diameter in the water-swelled state is 2 to 50 μm,

[0036] The components (a1) and (a3) are compounded in such a manner that the total charge of the aforementioned component (A) in the composition is negative,

[0037] The pH of the composition is 4.0 to 5.0.

[0038] (13) The composition according to (12), wherein the polymer in the aforementioned (a1) is a copolymer having a compound having one or more groups selected from a sulfonic acid group and a sulfuric acid group as a monomer.

[0039] (14) The composition according to (12) or (13), wherein the monomer in the aforementioned (a1) is sodium acryloyldimethyltaurate.

[0040] (15) The composition according to any one of (12) to (14), wherein the copolymer in the aforementioned (a1) is a (sodium acryloyldimethyltaurate / dimethylacrylamide) crosslinked polymer.

[0041] (16) The composition according to any one of (12) to (15), wherein the average particle diameter in the water-swelled state of the aforementioned (a1) component obtained by measurement using a laser analysis type particle size distribution meter is less than 2 μm.

[0042] (17) The composition according to any one of (12) to (16), wherein the cationic polymer in the aforementioned (a3) is at least one selected from the group consisting of cationized hydroxyalkyl cellulose, cationized cellulose, cationized guar gum, cationized locust bean gum, cationized chitosan, cationized oligosaccharide, cationized starch derivative, acrylamide-acrylic acid-dimethyldiallylammonium chloride copolymer, and a sulfuric acid solution of vinylpyrrolidone-N,N-dimethylaminoethyl methacrylate copolymer.

[0043] (18) The composition according to any one of (12) to (17), wherein the aforementioned (A) component has an irregular shape in the composition.

[0044] (19) The composition according to (12) to (18), which further comprises (C) a polyhydric alcohol.

[0045] (20) The composition according to (19), wherein the aforementioned (C) component is at least one selected from the group consisting of glycerol and polyglycerol.

[0046] (21) The composition according to (19) or (20), wherein the aforementioned (C) component further comprises at least one selected from the group consisting of dihydric alcohols having 3 to 6 carbon atoms.

[0047] (22) The composition according to any one of (12) to (21) is in the form of a solution, suspension, dispersion, emulsion, cream, ointment, gel, lotion, foam, paste, or spray.

[0048] (23) The composition according to any one of (12) to (22) is a cosmetic composition.

[0049] According to the present invention, there is provided a composition having an excellent effect of improving skin roughness, having a pH within a specific range, and containing a specific polymer. By using the composition of the present invention, skin roughness can be improved well. In addition, by using the composition of the present invention, the skin can also be moisturized well. Detailed Description

[0050] According to one aspect of the present invention, there is provided a composition comprising: (A) a microgel, and (B) a copolymer of 2-methacryloyloxyethyl phosphorylcholine and butyl methacrylate. The component (A) in the composition contains (a1) a polymer having at least one group selected from a sulfonic acid group and a sulfate group, and the component (A) satisfies: (a2) it has an irregular shape in the composition. In addition, the pH of the composition is 4.0 to 5.0. In the present invention, the irregular shape means a shape other than spherical (such as spherical synthesized by emulsion polymerization, etc.), broken flakes, plates, scales, needles, etc. that have a fixed shape.

[0051] According to another aspect of the present invention, there is provided a composition comprising (A) a microgel. The component (A) in the composition contains (a1) a polymer having at least one group selected from a sulfonic acid group and a sulfate group, contains (a3) a cationic polymer, and the component (A) satisfies: (a4) the average particle diameter in the water-swollen state is 2 to 50 μm. The pH of the composition is 4.0 to 5.0. The average particle diameter of the microgel in the water-swollen state in the composition refers to the particle diameter when the cumulative value in the particle size distribution is 50%, and it is a value measured using an aqueous solution containing 0.05% by mass of NaCl as a solvent. This measurement can be carried out by measurement using a laser analysis type particle size distribution meter, or other known methods (such as measurement based on microscopic observation image analysis) can also be used. In this measurement, when the shape of the microgel is spherical, its diameter (outer diameter) is set as the particle diameter. The shape of the microgel includes irregular shapes. When the shape of the microgel is other than spherical, the longest part of its shape can be set as the particle diameter. This average particle diameter is the average particle diameter of the (A) microgel including both the (a1) component and the (a3) component, and substances that do not include the (a3) component are not used for calculating the average particle diameter.

[0052] The composition of the present invention contains a microgel. Generally, a "microgel" refers to internally crosslinked polymer fine particles, which have the fluidity like a liquid, but are an aggregate of fine-grained gels. The microgel maintains the characteristics of a polymer gel in terms of structure such as a three-dimensional crosslinked structure and a surface that is not easily changed, and has the characteristic of colloidal dispersion in a solvent.

[0053] The polymer having one or more groups selected from a sulfonic acid group and a sulfate group in the present invention is not limited. It may have a structure in which a sulfonic acid group or its salt, a sulfate group or its salt is bonded to a polymer main chain such as polyacrylic acid or polymethacrylic acid via a spacer, or may be a polymer having a sulfonic acid / sulfate group derived from nature. Additionally, it may also be a thickener. The polymer having one or more groups selected from a sulfonic acid group and a sulfate group in the present invention is preferably a thickener bonded with a sulfonic acid group. Even for a sulfonic acid group, from the viewpoints of stability, safety, etc., a thickener bonded with taurine or its salt is more preferred.

[0054] The polymer having one or more groups selected from a sulfonic acid group and a sulfate group in the present invention is not limited, and is preferably a copolymer using a compound having one or more groups selected from a sulfonic acid group and a sulfate group as a monomer. As monomers in such a copolymer, there is no limitation. As specific examples, ammonium acryloyldimethyltaurate, etc. can be preferably cited. Additionally, as such a copolymer, there is no limitation. As specific examples, ammonium acryloyldimethyltaurate / behenyl alcohol polyether-25 methacrylate crosslinked polymer, (ammonium acryloyldimethyltaurate / vinylpyrrolidone) copolymer, (sodium acryloyldimethyltaurate / dimethylacrylamide) crosslinked polymer, etc. can be preferably cited. These copolymers are not limited, and commercially available products can be used.

[0055] The shape of the polymer having one or more groups selected from a sulfonic acid group and a sulfate group in the present invention is not limited. It may exhibit a fixed shape such as spherical, crushed flake, plate-like, scaly, needle-like, etc., or may be an irregular shape. Additionally, the average particle diameter of the polymer having one or more groups selected from a sulfonic acid group and a sulfate group in the composition of the present invention in the water-swollen state is preferably less than 2 μm. The average particle diameter of the polymer having one or more groups selected from a sulfonic acid group and a sulfate group in the water-swollen state refers to the particle diameter when the cumulative value in the particle size distribution is 50%, and is a value measured using an aqueous solution containing 0.05 mass% NaCl as a solvent. This measurement can be carried out by measurement based on a laser analysis type particle size distribution meter, or other known methods (such as measurement based on microscopic observation image analysis, etc.) can also be used. In such a measurement, when the shape of the aforementioned polymer is spherical, its diameter (outer diameter) is set as the particle diameter. When the shape of the aforementioned polymer includes an irregular shape and is other than spherical, the longest part of its shape can be set as the particle diameter.

[0056] As the copolymer of 2-methacryloyloxyethyl phosphorylcholine and butyl methacrylate in the present invention, there is no limitation, and a substance expressed by the cosmetic display name polyquaternium-51 can be used. Additionally, as long as it is a commercially available product, it can be used. As such commercially available products, for example, Lipidure PMB (manufactured by NOF Corporation), etc. can be cited.

[0057] As the cationic polymer in the present invention, there is no limitation. It is preferably at least one selected from the group consisting of cationized hydroxyalkyl cellulose, cationized cellulose, cationized guar gum, cationized locust bean gum, cationized chitosan, cationized oligosaccharide, cationized starch derivative, acrylamide-acrylic acid-dimethyldiallylammonium chloride copolymer, and vinylpyrrolidone-N,N-dimethylaminoethyl methacrylate copolymer sulfate solution. More preferably, it is at least one selected from the group consisting of cationized hydroxyalkyl cellulose (such as O-[2-hydroxy-3-(trimethylammonio)propyl] hydroxyethyl cellulose chloride, etc.) and vinylpyrrolidone-N,N-dimethylaminoethyl methacrylate copolymer sulfate solution. These cationic polymers are not limited, and commercially available products can be used.

[0058] The pH of the composition of the present invention is not limited as long as it is in the range of 4.0 to 5.0.

[0059] When the blending amount of the component (a1) in the composition of the present invention containing (A) microgel and (B) copolymer of 2-methacryloyloxyethyl phosphorylcholine and butyl methacrylate is set as MA, and the blending amount of the component (B) is set as MB, the MA / MB ratio is not limited, preferably 1.0 or more, and more preferably 1.5 to 8.

[0060] Therefore, according to a preferred embodiment of the present invention, there is provided a composition comprising (A) microgel and (B) copolymer of 2-methacryloyloxyethyl phosphorylcholine and butyl methacrylate. The component (A) in the composition contains (a1) a polymer having at least one group selected from a sulfonic acid group and a sulfate group, and the component (A) satisfies: (a2) it presents an irregular shape in the composition. In addition, the pH of the composition is 4.0 to 5.0. And when the blending amount of the component (a1) in the composition is set as MA and the blending amount of the component (B) is set as MB, the MA / MB ratio is 1.0 or more.

[0061] The microgel in the composition of the present invention containing (A) a microgel and (B) a copolymer of 2-methacryloyloxyethyl phosphorylcholine and butyl methacrylate is not limited, and preferably has an average particle diameter of 2 to 50 μm in the water-swollen state. The average particle diameter of the microgel in the water-swollen state in this composition refers to the particle diameter when the cumulative value in the particle size distribution is 50%, and is the value measured using an aqueous solution containing 0.05% by mass of NaCl as the solvent. This measurement can be carried out by measurement using a laser analysis type particle size distribution meter, or other known methods (such as measurement based on microscopic observation image analysis, etc.) can also be used. In this measurement, when the shape of the microgel is spherical, its diameter (outer diameter) is set as the particle diameter, and when the shape of the microgel includes an irregular shape and is other than spherical, the longest part of its shape can be set as the particle diameter.

[0062] Regarding the composition of the present invention containing (A) a microgel, and the component (A) contains (a1) a polymer having one or more groups selected from a sulfonic acid group or a sulfate group and contains (a3) a cationic polymer, and the component (A) satisfies (a4) having an average particle diameter of 2 to 50 μm in the water-swollen state, there is no limitation, and preferably, the components (a1) and (a3) are blended in such a manner that the total charge of the component (A) in the composition is negative.

[0063] In the present invention, the "total charge is negative" of the component (A) in the composition means that the total charge obtained by summing up the charges of all the particles of the component (A) contained in the composition is negative. The method for making the total charge negative is not particularly limited. For example, it can be carried out by blending (a1) and (a3) in such a manner that (a1) is included in a ratio range more than that of the two in which the charges are neutralized and the aggregate is most likely to be obtained.

[0064] In addition, regarding the composition of the present invention containing (A) a microgel, and the component (A) contains (a1) a polymer having one or more groups selected from a sulfonic acid group or a sulfate group and contains (a3) a cationic polymer, and the component (A) satisfies (a4) having an average particle diameter of 2 to 50 μm in the water-swollen state, there is no limitation, and preferably, the average particle diameter of the component (a1) in the water-swollen state is less than 2 μm.

[0065] Therefore, according to another preferred embodiment of the present invention, there is provided a composition comprising (A) microgels. The component (A) in the composition comprises (a1) a polymer having one or more groups selected from sulfonic acid groups and sulfuric acid groups, and comprises (a3) a cationic polymer, and the component (A) satisfies: (a4) the average particle diameter in the water-swollen state is 2 to 50 μm. In addition, the pH of the composition is 4.0 to 5.0. And the components (a1) and (a3) are blended in such a manner that the total charge of the component (A) in the composition is negative.

[0066] In addition, according to another preferred embodiment of the present invention, there is provided a composition comprising (A) microgels. The component (A) in the composition comprises (a1) a polymer having one or more groups selected from sulfonic acid groups and sulfuric acid groups, and comprises (a3) a cationic polymer, and the component (A) satisfies: (a4) the average particle diameter in the water-swollen state is 2 to 50 μm. In addition, the pH of the composition is 4.0 to 5.0. And the average particle diameter of the component (a1) in the water-swollen state is less than 2 μm.

[0067] In addition, according to another preferred embodiment of the present invention, there is provided a composition comprising (A) microgels. The component (A) in the composition comprises (a1) a polymer having one or more groups selected from sulfonic acid groups and sulfuric acid groups, and comprises (a3) a cationic polymer, and the component (A) satisfies: (a4) the average particle diameter in the water-swollen state is 2 to 50 μm. In addition, the pH of the composition is 4.0 to 5.0. And the components (a1) and (a3) are blended in such a manner that the total charge of the component (A) in the composition is negative. Further, the average particle diameter of the component (a1) in the water-swollen state is less than 2 μm.

[0068] In addition, according to another preferred embodiment of the present invention, there is provided a composition comprising (A) microgels. The component (A) in the composition comprises (a1) a polymer having one or more groups selected from sulfonic acid groups and sulfuric acid groups, and comprises (a3) a cationic polymer, and the component (A) satisfies: (a4) the average particle diameter in the water-swollen state is 2 to 50 μm. The pH of the composition is 4.0 to 5.0. In addition, the (A) microgels in the composition are irregular in shape. And such a composition can be blended with the components (a1) and (a3) in such a manner that the total charge of the component (A) in the composition is negative, and / or the average particle diameter of the component (a1) in the water-swollen state can be less than 2 μm.

[0069] The composition of the present invention may further contain polyols. Such polyols are not limited as long as they are alcohols having two or more hydroxyl groups in the same molecule, and examples thereof include glycerol, diglycerol, polyglycerol, 1,3-butanediol, ethylene glycol, propylene glycol, dipropylene glycol, polyethylene glycol, polypropylene glycol, polyethylene glycol-polypropylene glycol, trimethylolethane, trimethylolpropane, erythritol, pentaerythritol, sorbitan, glucose, sorbitol, maltitol, sucrose, raffinose, hexanediol, 1,2-pentanediol, trehalose, and the like. In the composition of the present invention, as the polyol, it is preferably to contain one or more selected from the group consisting of glycerol and polyglycerol, and more preferably to further contain one or more selected from the group consisting of diols having 3 to 6 carbon atoms.

[0070] The composition of the present invention is not limited and can be made into a cosmetic composition. The cosmetic composition in the present invention refers to a composition used for cosmetic purposes.

[0071] The composition of the present invention is not limited and can be made into a topical composition. When the composition of the present invention is made into a topical composition, known components (additives) that are formulated into the topical composition can be further formulated. Such components are not limited, and examples thereof include emulsifiers, humectants, solvents, emollients, stabilizers, thickeners, preservatives, lubricants, chelating agents, fillers, excipients, powders, fragrances, flavorings, absorbents, dyes, opacifiers, antioxidants, vitamins, amino acids, neutralizing agents, buffering agents, and the like.

[0072] As a method for adjusting the pH of the composition in the present invention, as long as a general method is used, as components, there is no limitation, and inorganic and organic basic components and acidic components that are also used as neutralizing agents and buffering agents can be used. An appropriate amount of such components can be added to the composition of the present invention. In the present invention, an appropriate amount means an amount at the level commonly used by those skilled in the art when preparing a desired composition, and there is no particular limitation.

[0073] The topical composition in the present invention can be any of liquid, semi-solid, and solid, and is not limited. It is preferably in the form of a solution, suspension, dispersion, emulsion, cream, ointment, gel, lotion, foam, paste, or spray.

[0074] Examples

[0075] The present invention will be specifically described according to the following examples, but the present invention is not limited to these examples. Unless otherwise specified, the content is expressed in mass%. In addition, the average particle size was measured using a laser analysis type particle size distribution meter (Microtrac HRA (Microtrac BEL)), and the value at which the cumulative value in the particle size distribution is 50% was used.

[0076] Evaluation of moisturizing property

[0077] The test site was set as the inner part of the front wrist of 4 healthy people aged 40. For each person, 4 areas of 2 cm × 3 cm were prepared, and the areas to be coated with 12 μl of the 4 kinds of compositions shown in Table 1 were randomly set. The coated areas were washed with soap, and the water content of the stratum corneum before coating the composition was measured using a Corneometer (Courage + Khazaka). 4 hours after coating each composition, the water content of the stratum corneum was measured in the same way. The change value after coating was calculated with the value before coating set as 1.

[0078] As shown in Table 1, compared with Comparative Example 1 which is only a solvent, Comparative Example 2, Comparative Example 3, and Example 1 containing Component (A) and Component (B) have high moisture retention. Furthermore, in Example 1 containing both Component (A) and Component (B), a higher moisturizing effect is shown compared with Comparative Example 2 and 3 containing equal amounts separately.

[0079] [Table 1]

[0080]

[0081] ※1 Aristoflex HMB (CLARIANT)

[0082] ※2 Lipidure PMB (NOF Corporation)

[0083] Evaluation of the effect of restoring rough skin

[0084] Inducing skin roughness

[0085] The test site was set as the inner part of the front wrist of healthy people aged 20 - 50. A medical cotton sheet of 2.5 cm × 3.4 cm was impregnated with a 10% aqueous solution of sodium lauryl sulfate and pasted, and covered with a medical moisture-permeable adhesive sheet. After 1 hour, they were removed and washed with water, and left open in the air for 2 hours.

[0086] Application of the sample

[0087] 50 μL of the sample was coated in an area of 3.5 cm × 5 cm including the area where skin roughness was induced. Regarding the coating, it was carried out twice in the morning and evening after inducing skin roughness and until the end of the test.

[0088] Evaluation of the recovery effect

[0089] Evaluation is carried out based on the recovery rate of the amount of moisture in the stratum corneum. The amount of moisture in the stratum corneum is measured using a Corneometer (Courage + Khazaka) for the area where skin roughness has been induced. Measurement is carried out before inducing skin roughness, after inducing skin roughness, and 24 hours or 48 hours after applying the sample from the induction of skin roughness, and evaluation is carried out using the recovery rate based on the following formula (1).

[0090] Recovery rate (%) = (value after applying the sample - value after inducing skin roughness) / (value before inducing skin roughness - value after inducing skin roughness) × 100... Formula (1)

[0091] Test 1

[0092] The composition and results of the lotion-like composition as the sample are shown in Table 2. In the test, on the inner side of the forearms of 10 male subjects, each subject applied all the samples, and the average value of the recovery rate after 24 hours was calculated. Compared with Reference 1 which is a general lotion-like composition, Examples 2 and 3 that satisfy the present composition and pH showed a high recovery rate, and it can be regarded that they have an excellent effect of promoting improvement on the part where skin roughness occurs. On the other hand, in Comparative Example 4 that does not contain Component B, Comparative Example 5 that uses a non-microgel without a sulfonic acid group or a sulfate group instead of Component A, Comparative Example 6 that uses a microgel that is not an irregular shape, and Comparative Example 7 where the pH does not satisfy the present conditions, high promotion effects like those in Examples 2 and 3 were not observed.

[0093] [Table 2]

[0094]

[0095] Test 2

[0096] The composition and results of the lotion-like composition as the sample are shown in Table 3. In the test, for the same female subject, it was carried out 5 times at different times. On two forearms, each sample was applied by changing the position each time, and the average value of the recovery rate after 48 hours was calculated. For Examples 4 and 5, the charge neutralization ratio of Component (a1) to (a3) is (a1):(a3) = 4:6 in terms of the pure product weight ratio, and the total charge of the composition shown in Table 3 is negative. Compared with Reference 2 with the pH adjusted to 4.5, Examples 4 and 5 that satisfy the present composition showed a high recovery rate, and it can be regarded that they have an excellent effect of promoting improvement on the part where skin roughness occurs. On the other hand, in Comparative Example 8 that contains polyhydric alcohol but does not contain Components A and B, Comparative Example 9 and Comparative Example 10 that contain a1 as a spherical microgel but do not contain a3, and Comparative Example 11 where the component composition is satisfied but the pH does not fall within the present range, high improvement effects like those in Examples 4 and 5 were not observed.

[0097] [Table 3]

[0098]

[0099] Other ratios

[0100] Example 6: Beauty Liquid (pH 4.5)

[0101] The formulation ratio of the beauty liquid falling within the scope of the composition of the present invention is shown as Example 6 below. Add 2 - 8, 12 - 13, and 15 - 16 to a part of water and mix. Add the substance obtained by mixing 9 - 11, 17, and 19 thereto and emulsify using a homogenizer. Add the substance obtained by dissolving 1 in the remaining water, then adding 2 and dissolving 16, add 18 and mix uniformly to obtain a beauty liquid falling within the scope of the composition of the present invention. The obtained beauty liquid has an excellent effect of restoring rough skin.

[0102] [Table 4]

[0103] Table 4: Formulation Ratio of Example 6

[0104]

[0105] Example 7: Lotion (pH 4.7)

[0106] The formulation ratio of the lotion falling within the scope of the composition of the present invention is shown as Example 7 below. Dissolve 1 in a part of water, add 2 and mix. Add 3 - 18 to the remaining water and mix uniformly, then add the pre - mixed aqueous solution thereto to obtain a lotion falling within the scope of the composition of the present invention. The obtained lotion has an excellent effect of restoring rough skin.

[0107] [Table 5]

[0108] Table 5: Formulation Ratio of Example 7

[0109]

[0110] Example 8: Facial Cleanser (pH 4.7)

[0111] The formulation ratio of the facial cleanser falling within the scope of the composition of the present invention is shown as Example 8 below. Dissolve 1 in a part of water, add 2 and mix. Add 3 - 5, 7, 8, 11, 12 - 15, 17, 18 to the remaining water and mix uniformly, add the homogeneous substance obtained by adding 9, 16, and 19 to 6 and mix. Add 10 thereto, emulsify using a homogenizer, add the aqueous solution of 1 and 2 and mix to obtain a facial cleanser falling within the scope of the composition of the present invention. The obtained facial cleanser has an excellent effect of restoring rough skin.

[0112] [Table 6]

[0113] Table 6: Formulation Ratio of Example 8

[0114]

[0115] ※3 Aristoflex AVC (CLARIANT), average particle size is 5.8 μm

[0116] Example 9: Mask Sheet Impregnating Solution (pH 4.2)

[0117] The formulation ratio of the mask sheet impregnating solution falling within the scope of the composition of the present invention is shown as Example 9 below. Dissolve 1 in 19, add 2 and mix. Further add 3, 5, 14 to 18 and dissolve. Add thereto the substance obtained by adding 8 to 13 to 4 and mixing, and mix to obtain a mask sheet impregnating solution falling within the scope of the composition of the present invention. The obtained mask sheet impregnating solution has excellent skin roughness recovery effect.

[0118] [Table 7]

[0119] Table 7: Formulation Ratio of Example 9

[0120] No. Ingredient Blending amount 1 (Ammonium acryloyldimethyltaurate / VP) copolymer (※3) 0.5 2 Polyquaternium-51 solution (※2) 0.1 3 Glycerin 2 4 BC 9 5 PEG-6 3 6 Methyl gluceth-10 0.5 7 Sodium cocoyl methyl taurate 0.1 8 Polyglyceryl-2 diisostearate 0.2 9 Isostearic acid 0.2 10 Isostearyl alcohol 0.2 11 PEG-60 hydrogenated castor oil 0.2 12 Hydrogenated polydecene 0.5 13 Phytosteryl / octyldodecyl lauroyl glutamate 0.1 14 Glycylglycine 1.5 15 Buffer Appropriate amount 16 Preservative Appropriate amount 17 Chelating agent Appropriate amount 18 Stabilizer Appropriate amount 19 Water The balance

[0121] Example 10: Mist Lotion (pH 4.8)

[0122] The formulation ratio of the mist lotion falling within the scope of the composition of the present invention is shown as Example 10 below. Dissolve 1 in 14, add 2 and mix. Add 3 to 6, 8 to 13 thereto and mix uniformly, then add 7 and mix to obtain a lotion that can be sprayed in a mist form from a gas-free container using a dispenser. The obtained lotion that can be sprayed in a mist form from a gas-free container using a dispenser has excellent skin roughness recovery effect.

[0123] [Table 8]

[0124] Table 8: Formulation Ratio of Example 10

[0125] No. Ingredient Blending amount 1 (Ammonium acryloyldimethyltaurate / VP) copolymer (※3) 0.12 2 Polyquaternium-51 solution (※2) 0.04 3 Diglycerin 1 4 BG 7 5 1,3-Propanediol 3 6 Ethanol 5 7 Dimethicone / vinyl dimethicone crosspolymer aqueous dispersion (※4) 12 8 Acrylates / C10-30 alkyl acrylate crosspolymer 0.06 9 PEG-12 dimethicone 0.4 10 Buffer Appropriate amount 11 Preservative Appropriate amount 12 Chelating agent Appropriate amount 13 Neutralizing agent Appropriate amount 14 Water The balance

[0126] ※4 DOWSIL BY 29-129 (TORAY DOW Co., Ltd.)

[0127] Example 11: All-in-One Gel (pH 4.8)

[0128] The formulation ratio of the all-in-one gel falling within the scope of the composition of the present invention is shown below as Example 11. Dissolve 1 in a part of water, add 2 and mix. Heat a part of water to 90 °C, dissolve 7, add 3 and make it uniform, then cure it at room temperature and crush it with a homogenizer to obtain a paste-like gel. Heat the remaining water to 50 °C, dissolve 9, add 5 in which 8 is dissolved, then add the material that moistens 17 by heating and dissolving 6 in 4, and mix evenly. Add the material mixed with 10 to 14 and emulsify it using a homogenizer. Mix 18 to 20 with the previously prepared aqueous solutions of 1 and 2 and the paste-like gel to obtain an all-in-one gel falling within the scope of the composition of the present invention. The obtained all-in-one gel has excellent effect on restoring rough skin.

[0129] [Table 9]

[0130] Table 9: Formulation Ratio of Example 11

[0131]

[0132] Example 12: Skin Lotion (pH 4.8)

[0133] The formulation ratio of the skin lotion falling within the scope of the composition of the present invention is shown below as Example 12. Dissolve 1 in a part of water, dissolve 2 and 3 in another part of water, and then mix these two aqueous solutions. The average particle size of the resulting composition is 6.2 μm and the total charge is negative. Add 4 to 8, 12 to 16 to the remaining water and mix evenly. Add the material formed by mixing 9 to 11 and 19, then add 17 and emulsify it using a homogenizer. Then, add the previously prepared aqueous solutions of 1 to 3 and mix to obtain a skin lotion falling within the scope of the composition of the present invention. The obtained skin lotion has excellent effect on restoring rough skin.

[0134] [Table 10]

[0135] Table 10: Formulation Ratio of Example 12

[0136] No. Ingredient Blending amount 1 (Dimethylacrylamide / sodium acryloyldimethyltaurate) crosslinked polymer 0.3 2 Carrageenan 0.1 3 Polyquaternium-10 0.2 4 Glycerin 1 5 BG 5 6 Dipropylene glycol 5 7 Erythritol 1 8 Acrylates / C10-30 alkyl acrylate crosspolymer 0.15 9 Dimethicone (about 100 cs) 1 10 Tris (ethylhexanoic acid) glycerin 0.5 11 Limnanthes alba (meadowfoam) seed oil 0.5 12 PEG / PPG-14 / 7 dimethyl ether 1 13 Potassium methoxysalicylate 1 14 Buffer Appropriate amount 15 Preservative Appropriate amount 16 Chelating agent Appropriate amount 17 Neutralizing agent Appropriate amount 18 Stabilizer Appropriate amount 19 Food flavoring Appropriate amount 20 Water The balance

[0137] Example 13: Toner (pH 4.5)

[0138] The formulation ratio of the toner falling within the scope of the composition of the present invention is shown below as Example 13. The average particle size of the resulting composition is 2.2 μSubstance 2 is dissolved in a part of water and mixed with a substance in which Substance 1 is dissolved in the remaining water. Add Substance 17 and dissolve it. When mixing Substance 4 and Substance 16, add the substance formed by moistening Substances 6 and 7, the substance formed by dissolving Substances 8 to 10 in heated Substance 5 and mixing Substances 13, 14, and 19, and Substance 3, and mix them evenly. Then dissolve Substance 18 to obtain a lotion that falls within the scope of the composition of the present invention. The obtained lotion has an excellent effect of restoring rough skin.

[0139] [Table 11]

[0140] Table 11: Proportioning of Example 13

[0141] No. Ingredient Blending amount 1 (Dimethylacrylamide / sodium acryloyldimethyltaurate) crosslinked polymer 0.1 2 Polyquaternium-10 0.05 3 Glycerin 5 4 BG 5 5 Dipropylene glycol 5 6 Xanthan gum 0.1 7 Tremella polysaccharide 0.05 8 PPG-8 ceteth-20 0.1 9 PEG-12 dimethicone 0.05 10 PEG-10 phytosterol 0.02 11 PEG / PPG-17 / 4 dimethyl ether 2 12 Tranexamic acid 1 13 Tocopheryl acetate 0.1 14 Panthenol ethyl ether 0.05 15 Buffer Appropriate amount 16 Preservative Appropriate amount 17 Chelating agent Appropriate amount 18 Stabilizer Appropriate amount 19 Food flavoring Appropriate amount 20 Water The balance

[0142] Example 14: Emollient Cream (pH 4.9)

[0143] The proportion of the emollient cream that falls within the scope of the composition of the present invention is shown as Example 14 below. Substance 1 is dissolved in a part of water and mixed with a substance in which Substance 2 is dissolved in another part of water. The average particle size of the resulting composition is 4.0 μm and the total charge is negative. Add Substances 8, 5 to 7, 11 to 14 which are heated and dissolved in Substances 3 and 4 in the remaining water and mix them. Then add Substances 9, 10, and 20 and mix them using a homogenizer. Further, after adding Substances 15 to 19, add the aqueous solutions of Substances 1 and 2 prepared in advance and mix them to obtain an emollient cream that falls within the scope of the composition of the present invention. The obtained emollient cream has an excellent effect of restoring rough skin.

[0144] [Table 12]

[0145] Table 12: Proportioning of Example 14

[0146] No. Ingredient Blending amount 1 (Dimethylacrylamide / sodium acryloyldimethyltaurate) crosslinked polymer 0.5 2 Polyquaternium-10 0.3 3 Glycerin 1 4 Dipropylene glycol 5 5 Ethanol 7 6 PEG / PPG-14 / 7 dimethyl ether 5 7 Acrylates / C10-30 alkyl acrylate crosspolymer 0.1 8 Hydrogenated lecithin 0.2 9 Cetyl ethylhexanoate 0.5 10 Dimethicone (about 6 cs) 0.7 11 Hydroxypropyl methylcellulose 0.2 12 Hydrolyzed corn starch 2 13 Carbomer 0.5 14 Cellulose powder 10 15 Buffer Appropriate amount 16 Preservative Appropriate amount 17 Chelating agent Appropriate amount 18 Neutralizing agent Appropriate amount 19 Stabilizer Appropriate amount 20 Food flavoring Appropriate amount 21 Water The balance

[0147] Example 15: Body Lotion (pH 4.2)

[0148] The proportion of the body lotion that falls within the scope of the composition of the present invention is shown as Example 15 below. Substances 2 and 3 are dissolved in a part of water and mixed with a substance in which Substance 1 is dissolved in the remaining water. The average particle size of the resulting composition is 20 μm and the total charge is negative. Add Substances 4, 6, 12 to 18. Further, add the substance formed by heating and dissolving Substances 10 and 11 in Substance 5 and then adding Substances 7 to 9 and 19 and mixing them evenly to obtain a body lotion that falls within the scope of the composition of the present invention. The obtained body lotion has an excellent effect of restoring rough skin.

[0149] [Table 13]

[0150] Table 13: Proportioning of Example 15

[0151] No. Ingredient Blending amount 1 (Dimethylacrylamide / sodium acryloyldimethyltaurate) crosslinked polymer 0.2 2 Polyquaternium-10 0.1 3 Starch hydroxypropyltrimonium chloride 0.02 4 Glycerin 5 5 BG 10 6 Erythritol 0.1 7 Hydrogenated polydecene 0.3 8 Isostearic acid 0.4 9 Retinyl acetate 0.2 10 PEG-30 phytosterol 0.2 11 Sorbitan sesquiisostearate 0.03 12 Niacinamide 1 13 Bis-diethoxydiglycol cyclohexane 1,4-dicarboxylate 1 14 Rosa canina fruit extract 0.5 15 Buffer Appropriate amount 16 Preservative Appropriate amount 17 Chelating agent Appropriate amount 18 Stabilizer Appropriate amount 19 Food flavoring Appropriate amount 20 Water The balance

[0152] Example 16: Emulsion (pH 4.1)

[0153] The formulation ratio of the emulsion falling within the scope of the composition of the present invention is shown as Example 16 below. Dissolve 2 and 3 in a part of water and mix with the substance in which 1 is dissolved in another part of water. The average particle size of the resulting composition is 5.1 μm and the total charge is negative. Heat the remaining water to 70 °C, add and dissolve 16 dispersed in 5, then dissolve 15, 18, 20, and 21. Add the substance obtained by heating 7 - 14 to 70 °C and dissolving, add the substance obtained by mixing and dissolving 4, 17, 6, and 19, emulsify using a homogenizer, add the pre-prepared aqueous solution of 1 - 3, and cool to 35 °C to obtain an emulsion falling within the scope of the composition of the present invention. The resulting emulsion has an excellent effect on restoring rough skin.

[0154] [Table 14]

[0155] Table 14: Formulation Ratio of Example 16

[0156] No. Ingredient Blending amount 1 (Dimethylacrylamide / Sodium Acryloyldimethyltaurate) Crosslinked Polymer 0.12 2 Polyquaternium-10 0.03 3 Polyquaternium-39 Solution (purity 10%)※5 0.1 4 Glycerin 3 5 BG 7 6 Ethanol 5 7 Behenyl Alcohol 1 8 Stearyl Alcohol 0.5 9 Isododecane 2 10 Pentaerythrityl Tetra(ethylhexanoate) 2 11 Polydimethylsiloxane (about 6 cs) 3 12 Diphenylsilanoxy Phenyl Trimethylsiloxane 2 13 Glyceryl Stearate 0.5 14 Polysorbate-60 0.6 15 Sodium Stearoyl Methyl Taurate 0.2 16 Succinoglucan 0.1 17 3-O-Ethyl Ascorbic Acid 1 18 Buffer Appropriate amount 19 Preservative Appropriate amount 20 Chelating agent Appropriate amount 21 Water The balance

[0157] ※5 Merquat TM 3330PR Polymer (Lubrizol).

Claims

1. A composition, comprising: (A) a microgel; and (B) a copolymer of 2-methacryloyloxyethyl phosphorylcholine and butyl methacrylate, wherein the component (A) comprises (a1) a polymer having at least one group selected from a sulfonic acid group and a sulfate group, and the component (A) satisfies: (a2) presenting an irregular shape in the composition, the pH of the composition is 4.0 to 5.

0.

2. The composition according to claim 1, wherein, The polymer in the (a1) is a copolymer using a compound having at least one group selected from a sulfonic acid group and a sulfate group as a monomer.

3. The composition according to claim 2, wherein The monomer in the (a1) is ammonium acryloyldimethyltaurate.

4. The composition according to claim 2, wherein, The copolymer in the (a1) is at least one selected from the group consisting of ammonium acryloyldimethyltaurate / behenyl polyether-25 methacrylate cross-linked polymer and (ammonium acryloyldimethyltaurate / vinylpyrrolidone) copolymer.

5. The composition according to claim 1, wherein, The average particle size of the component (A) in the water-swollen state is 2 to 50 μm.

6. The composition according to claim 1, wherein, When the compounding amount of the component (a1) in the composition is set as MA and the compounding amount of the component (B) is set as MB, the MA / MB ratio is 1.0 or more.

7. The composition according to claim 1, further comprising (C) a polyol.

8. The composition according to claim 7, wherein, The component (C) is at least one selected from the group consisting of glycerol and polyglycerol.

9. The composition according to claim 8, wherein, The component (C) further comprises at least one selected from the group consisting of dihydric alcohols having 3 to 6 carbon atoms.

10. The composition according to any one of claims 1 to 9, presenting a form of a solution, a suspension, a dispersion, an emulsion, a cream, an ointment, a gel, a lotion, a foam, a paste or a spray.

11. The composition according to any one of claims 1 to 9, which is a cosmetic composition.

12. A composition, comprising (A) a microgel, wherein the component (A) comprises (a1) a polymer having at least one group selected from a sulfonic acid group and a sulfate group, and comprises (a3) a cationic polymer, and the component (A) satisfies: (a4) the average particle size in the water-swollen state is 2 to 50 μm, the components (a1) and (a3) are compounded in such a manner that the total charge of the component (A) in the composition is negative, the pH of the composition is 4.0 to 5.

0.

13. The composition according to claim 12, wherein, The polymer in the (a1) is a copolymer using a compound having at least one group selected from a sulfonic acid group and a sulfate group as a monomer.

14. The composition according to claim 13, wherein The monomer in the (a1) is sodium acryloyldimethyltaurate.

15. The composition according to claim 13, wherein, The copolymer in the (a1) is a (sodium acryloyldimethyltaurate / dimethylacrylamide) cross-linked polymer.

16. The composition according to claim 12, wherein, The average particle size of the component (a1) in the water-swollen state obtained by measurement using a laser analysis type particle size distribution meter is less than 2 μm.

17. The composition according to claim 12, wherein, The cationic polymer in (a3) is one or more selected from the group consisting of cationized hydroxyalkyl cellulose, cationized cellulose, cationized guar gum, cationized locust bean gum, cationized chitosan, cationized oligosaccharide, cationized starch derivative, acrylamide-acrylic acid-dimethyldiallylammonium chloride copolymer, and vinylpyrrolidone-N,N-dimethylaminoethyl methacrylate copolymer sulfate solution.

18. The composition according to claim 12, wherein, The component (A) has an irregular shape in the composition.

19. The composition according to claim 12, further comprising (C) polyol.

20. The composition according to claim 19, wherein, The component (C) is one or more selected from the group consisting of glycerol and polyglycerol.

21. The composition according to claim 20, wherein The component (C) further comprises one or more selected from the group consisting of diols having 3 to 6 carbon atoms.

22. The composition according to any one of claims 12 to 21 is in the form of a solution, suspension, dispersion, emulsion, cream, ointment, gel, lotion, foam, paste or spray.

23. The composition according to any one of claims 12 to 21 is a cosmetic composition.

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