Formula and preparation process of pet toothpaste for dogs

Abstract

The invention relates to the technical field of pet toothpaste preparation, and particularly discloses a dog pet toothpaste formula and a preparation process, the formula selects food-grade silicon dioxide as a friction agent, a sorbitol solution as a humectant and xanthan gum as an adhesive, and is matched with a sodium lauroyl sarcosinate foaming agent and a chicken flavor and taurine compound flavoring agent; and nisin and lysozyme antibacterial components. The preparation process comprises the following steps: stirring in a water bath at a constant temperature of 40-60 DEG C to prepare a basic paste A, carrying out vacuum defoaming and ultrasonic dispersion to obtain a uniform paste B, dispersing the antibacterial agent and the natural enzyme preparation solution C by a high-pressure homogenizer, standing and curing, and finally carrying out twin-screw extrusion molding, ultraviolet irradiation sterilization and subpackaging. According to the formula and the process, the toothpaste is clean, efficient, safe, stable and good in palatability, the oral health problem of dogs can be effectively solved, and the requirement of the market for high-quality dog pet toothpaste is met.

Description

Technical Field

[0001] The present invention relates to the technical field of pet toothpaste production, and specifically to a formula and production process of dog-use pet toothpaste. Background Art

[0002] With the change of pet-raising concept, dogs, as important companion animals of humans, their oral health problems have attracted increasing attention. Bacterial growth and plaque accumulation in the dog's oral cavity are likely to cause periodontitis, bad breath and other diseases, which not only affect the dog's quality of life, but also may threaten its overall health. Therefore, dog-use pet toothpaste has become an important product for maintaining the dog's oral hygiene.

[0003] At present, there are many deficiencies in the formula and production process of dog-use pet toothpaste on the market. In terms of the formula, the abrasives used in some toothpastes have poor cleaning effects and are difficult to effectively remove dental plaque; the selection of some humectants and binders is inappropriate, resulting in poor stability of the paste body, prone to layering and drying, affecting the product shelf life and use effect. At the same time, the antibacterial components are single or have low safety. Some toothpastes add chemical preservatives, posing potential safety risks and unable to meet the needs of pet owners for safe and efficient products. In addition, the combination of flavoring agents is unreasonable, the palatability of the toothpaste is poor, and dogs resist using it, making it difficult to effectively implement daily oral care.

[0004] In terms of the production process, the traditional process lacks effective control over the uniformity and stability of the paste body. The ordinary stirring and mixing method is difficult to fully disperse each component, resulting in non-uniform paste quality; no defoaming treatment is carried out, there are bubbles in the paste body, affecting the extrusion molding effect and product appearance; no efficient dispersion and homogenization means are adopted, and functional components such as antibacterial agents and natural enzyme preparations cannot be evenly distributed and cannot fully exert their efficacy, thereby affecting the antibacterial, cleaning and other properties of the toothpaste.

[0005] In summary, the existing dog-use pet toothpaste needs to be improved in both formula and production process. There is an urgent need to develop a dog-use pet toothpaste with a scientific formula, safe and effective, and an advanced production process to improve product performance and better meet the market demand and the actual needs of dog oral care. Summary of the Invention

[0006] (I) Technical Problems to be Solved In view of the deficiencies of the prior art, the present invention provides a formula and production process of dog-use pet toothpaste, which solves the problems mentioned in the above background art.

[0007] (II) Technical Solutions In order to achieve the above object, the present invention discloses a production process of dog-use pet toothpaste, including the following steps: S1: Add the purified and pretreated abrasives, humectants, and binders into a mixing container according to a certain mass ratio, and stir them at a constant temperature in a water bath at 40 - 60°C until a homogeneous paste is formed. Then add the pretreated foaming agent and flavoring agent, continue stirring and reacting, and cool to room temperature to obtain the basic paste A; S2: Transfer the basic paste A to a vacuum degassing machine, degas it under a vacuum degree of -0.08 to -0.1 MPa for 20 - 40 minutes, and then inject it into an ultrasonic dispersion device. Treat it at a frequency of 20 - 40 kHz for 10 - 20 minutes to obtain a uniform paste B; S3: Dissolve the antibacterial agent and natural enzyme preparation in deionized water according to a ratio to form solution C, and disperse solution C into the uniform paste B with a pressure of 50 - 80 MPa through a high-pressure homogenizer. After mixing, let it stand and ripen for 2 - 4 hours; S4: Inject the ripened paste into a twin-screw extruder, extrude and form it at 30 - 50°C, and then sterilize it by ultraviolet irradiation and package it to obtain dog toothpaste.

[0008] Preferably, the abrasive described in S1 is food-grade silica, the humectant described in S1 is sorbitol solution, and the binder described in S1 is xanthan gum; The so-called certain mass ratio in S1 is that the ratio of abrasive: humectant: binder = 5:3:1; The constant-temperature stirring condition described in S1 is stirring in a 50°C water bath for 30 minutes.

[0009] Preferably, the pretreated foaming agent described in S1 is sodium lauroyl sarcosinate, and the pretreatment method is to mix it with propylene glycol in a mass ratio of 1:2 and heat it to 50°C for dissolution; The flavoring agent described in S1 is a complex of chicken flavor essence and taurine, and the addition amount is 0.5 - 1.5% of the total mass of the paste.

[0010] Preferably, the ultrasonic dispersion device described in S2 is provided with a spiral flow channel structure, and the flow rate of the paste during the dispersion process is controlled at 0.5 - 1.2 L / min.

[0011] Preferably, the antibacterial agent described in S3 is nisin, and the natural enzyme preparation is lysozyme; The so-called dissolution according to a ratio in S3 is that the mass ratio of antibacterial agent: natural enzyme preparation = 2:1, and the total addition amount of solution C is 3 - 5% of the mass of paste B.

[0012] Preferably, the screw rotation speed of the twin-screw extruder described in S4 is 80 - 120 rpm, and the extrusion pressure is 0.8 - 1.2 MPa; The wavelength of the ultraviolet irradiation sterilization described in S4 is 254 nm, and the irradiation time is 5 - 10 minutes.

[0013] Preferably, the diameter range of the extruded paste is 3-5 mm, and the length is cut to 10-15 cm.

[0014] Preferably, the aluminum-plastic composite tube is used for the sub-packaging in S4, and the inner wall of the tube is purged with nitrogen before sub-packaging to isolate oxygen.

[0015] Preferably, the nozzle aperture of the high-pressure homogenizer in S3 is 0.1-0.3 mm, and the number of homogenization cycles is 3-5 times.

[0016] Preferably, the present invention also includes a formula for canine pet toothpaste, and the formula comprises the following components by mass percentage: Food-grade silica 10-15%, sorbitol solution 8-12%, xanthan gum 2-4%, sodium lauroyl sarcosinate 1-3%, chicken flavor essence 0.3-0.8%, taurine 0.2-0.5%, nisin 0.1-0.3%, lysozyme 0.05-0.15%, and deionized water in the balance.

[0017] (III) Beneficial technical effects The formula and production process of the canine pet toothpaste described in the present invention have multiple significant beneficial effects compared with the prior art: High-efficiency cleaning: Food-grade silica is used as an abrasive in the formula. It has a moderate hardness and fine particles, and can effectively remove dental plaque and food residues without damaging the surface of the dog's teeth. The cleaning effect is significantly better than that of traditional abrasives. At the same time, the sorbitol solution is used as a humectant to keep the paste at an appropriate humidity, ensuring that the abrasive plays the best role in the cleaning process.

[0018] Safe and healthy: Nisin is selected as the antibacterial agent, and lysozyme is used as the natural enzyme preparation. Both are natural ingredients with high safety and no potential risk of chemical preservatives. Nisin and lysozyme are compounded at a specific mass ratio of 2:1. Through their synergistic effect, they can effectively inhibit the growth of various harmful bacteria in the dog's oral cavity, maintain oral health while avoiding adverse effects on the dog's body, and meet the needs of pet owners for safe products.

[0019] Stable and high-quality: Using xanthan gum as the binder, it is mixed with sorbitol solution and food-grade silica in a mass ratio of 5:3:1. Combining with the constant-temperature stirring process in a water bath at 40 - 60°C, the components are fully integrated to form a stable homogeneous paste. In the production process, defoaming is carried out by a vacuum defoaming machine at a vacuum degree of -0.08 - -0.1 MPa for 20 - 40 minutes, effectively removing the air bubbles in the paste and avoiding problems such as voids and fractures during extrusion molding; an ultrasonic dispersion device is combined with a spiral flow channel structure, and processed at a frequency of 20 - 40 kHz for 10 - 20 minutes to make the paste more evenly dispersed; a high-pressure homogenizer is used with a pressure of 50 - 80 MPa, a nozzle aperture of 0.1 - 0.3 mm, and 3 - 5 homogenization cycles to ensure that the antibacterial agent and natural enzyme preparation are evenly dispersed in the paste, significantly improving the stability of the paste, preventing stratification and drying, extending the product shelf life, and ensuring the uniformity of product quality.

[0020] Good palatability: The flavoring agent uses a complex of chicken flavor essence and taurine, and the addition amount is 0.5 - 1.5% of the total mass of the paste. It can not only give the toothpaste the fragrance that dogs like, but also use the special taste of taurine to attract dogs to actively cooperate in cleaning the oral cavity, greatly improving the palatability of the toothpaste, solving the problem that traditional toothpaste is resisted by dogs, and making daily oral care easier to implement.

[0021] Precise molding and effective sterilization: The twin-screw extruder extrudes at a screw speed of 80 - 120 rpm and an extrusion pressure of 0.8 - 1.2 MPa under the condition of 30 - 50°C, combined with cutting with a paste diameter of 3 - 5 mm and a length of 10 - 15 cm, which can accurately control the shape and specifications of the toothpaste to meet different packaging and use requirements. Ultraviolet irradiation sterilization with a wavelength of 254 nm for 5 - 10 minutes can efficiently kill the bacteria on the surface of the paste. Combined with the nitrogen purging treatment of the inner wall of the aluminum-plastic composite tube before filling to isolate oxygen, it further ensures the safety and effectiveness of the product during storage and use. Specific implementation mode

[0022] To facilitate the understanding of the present invention, the present invention will be described more comprehensively below. Preferred embodiments of the present invention are given below. However, the present invention can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the understanding of the disclosure content of the present invention more thorough and comprehensive.

[0023] The following further details the formula and production process of a canine pet toothpaste described in the present invention in combination with specific examples and comparative examples.

[0024] Example 1: Formula:

[0025] Manufacturing process: Add the purified and pre-treated food-grade silica, sorbitol solution and xanthan gum in the above formula amounts into a mixing container in a mass ratio of 5:3:1, and stir constantly in a water bath at 50 °C for 30 minutes to form a homogeneous paste. Then add the pre-treated sodium lauroyl sarcosinate (mixed with propylene glycol in a mass ratio of 1:2 and heated to 50 °C for dissolution), chicken flavor essence and taurine complex (the addition amount is 0.5% of the total mass of the paste), continue to stir and react, and then cool to room temperature to obtain the basic paste A.

[0026] Transfer the basic paste A to a vacuum degassing machine, degas at a vacuum degree of -0.08 MPa for 20 minutes, and then inject it into an ultrasonic dispersion device (equipped with a spiral flow channel structure, and the paste flow rate is controlled at 0.5 L / min during the dispersion process), and process it at a frequency of 20 kHz for 10 minutes to obtain a uniform paste B.

[0027] Dissolve nisin and lysozyme in deionized water in a mass ratio of 2:1 to form solution C (the total addition amount of solution C is 3% of the mass of paste B), and disperse solution C into the uniform paste B at a pressure of 50 MPa through a high-pressure homogenizer (the nozzle aperture is 0.1 mm, and the homogenization cycle times is 3 times), and let it stand and ripen for 2 hours after mixing.

[0028] Inject the ripened paste into a twin-screw extruder (the screw speed is 80 rpm, and the extrusion pressure is 0.8 MPa), extrude and form at 30 °C (the diameter of the extruded and formed paste is 3 mm, and the length is cut to 10 cm), irradiate with ultraviolet light of wavelength 254 nm for sterilization for 5 minutes, and then package it with an aluminum-plastic composite pipe (the inner wall of the pipe is purged with nitrogen before packaging to isolate oxygen) to obtain the dog toothpaste.

[0029] Example 2: Formula:

[0030] Manufacturing process: Add the purified and pre-treated food-grade silica, sorbitol solution, and xanthan gum in the above formula amounts to a mixing container at a mass ratio of 5:3:1, and stir constantly in a water bath at 50 °C for 30 minutes to form a homogeneous paste. Add the pre-treated sodium lauroyl sarcosinate (mixed with propylene glycol at a mass ratio of 1:2 and heated to 50 °C for dissolution), chicken flavor essence, and taurine complex (the addition amount is 1% of the total mass of the paste), continue stirring and reacting, and then cool to room temperature to obtain the base paste A.

[0031] Transfer the base paste A to a vacuum degassing machine, degas at a vacuum degree of -0.09 MPa for 30 minutes, and then inject it into an ultrasonic dispersion device (equipped with a spiral flow channel structure, and the flow rate of the paste during dispersion is controlled at 0.8 L / min), and process it at a frequency of 30 kHz for 15 minutes to obtain a uniform paste B.

[0032] Dissolve nisin and lysozyme in deionized water at a mass ratio of 2:1 to form solution C (the total addition amount of solution C is 4% of the mass of paste B), and disperse solution C into the uniform paste B at a pressure of 65 MPa through a high-pressure homogenizer (the nozzle aperture is 0.2 mm, and the homogenization cycle times are 4 times), and let it stand and ripen for 3 hours after mixing.

[0033] Inject the ripened paste into a twin-screw extruder (the screw speed is 100 rpm, and the extrusion pressure is 1.0 MPa), and extrude and form it at 40 °C (the diameter of the extruded and formed paste is 4 mm, and the length is cut to 12 cm). After irradiating and sterilizing with ultraviolet light with a wavelength of 254 nm for 8 minutes, package it with an aluminum-plastic composite tube (the inner wall of the tube is purged with nitrogen before packaging to isolate oxygen) to obtain dog pet toothpaste.

[0034] Example 3: Formula:

[0035] Manufacturing process: Add the purified and pre-treated food-grade silica, sorbitol solution, and xanthan gum in the above formula amounts to a mixing container at a mass ratio of 5:3:1, and stir constantly in a water bath at 50 °C for 30 minutes to form a homogeneous paste. Add the pre-treated sodium lauroyl sarcosinate (mixed with propylene glycol at a mass ratio of 1:2 and heated to 50 °C for dissolution), chicken flavor essence, and taurine complex (the addition amount is 1.5% of the total mass of the paste), continue stirring and reacting, and then cool to room temperature to obtain the base paste A.

[0036] Transfer the base paste A to a vacuum degassing machine and degas it for 40 minutes under a vacuum of -0.1 MPa. Then inject it into an ultrasonic dispersion device (equipped with a spiral flow channel structure, and the paste flow rate is controlled at 1.2 L / min during the dispersion process), and process it at a frequency of 40 kHz for 20 minutes to obtain a uniform paste B.

[0037] Dissolve nisin and lysozyme in deionized water at a mass ratio of 2:1 to form solution C (the total addition amount of solution C is 5% of the mass of paste B), and disperse solution C into the uniform paste B at a pressure of 80 MPa through a high-pressure homogenizer (the nozzle aperture is 0.3 mm, and the homogenization cycle times is 5 times). After mixing, let it stand and ripen for 4 hours.

[0038] Inject the ripened paste into a twin-screw extruder (the screw rotation speed is 120 rpm, and the extrusion pressure is 1.2 MPa), and extrude and form it at 50°C (the diameter of the extruded and formed paste is 5 mm, and the length is cut to 15 cm). After irradiating and sterilizing with ultraviolet light of wavelength 254 nm for 10 minutes, package it with an aluminum-plastic composite tube (the inner wall of the tube is purged with nitrogen before packaging to isolate oxygen) to obtain dog toothpaste.

[0039] Example 4: Formulation:

[0040] Manufacturing process: Add the purified and pretreated food-grade silica, sorbitol solution, and xanthan gum in the above formulation amounts to a mixing container at a mass ratio of 5:3:1, and stir constantly in a 40°C water bath for 30 minutes to form a homogeneous paste. Add the pretreated sodium lauroyl sarcosinate (mixed with propylene glycol at a mass ratio of 1:2 and heated to 50°C for dissolution), chicken flavor essence, and taurine complex (the addition amount is 0.7% of the total mass of the paste), continue to stir and react, and then cool to room temperature to obtain the base paste A.

[0041] Transfer the base paste A to a vacuum degassing machine and degas it for 25 minutes under a vacuum of -0.085 MPa. Then inject it into an ultrasonic dispersion device (equipped with a spiral flow channel structure, and the paste flow rate is controlled at 0.6 L / min during the dispersion process), and process it at a frequency of 25 kHz for 12 minutes to obtain a uniform paste B.

[0042] Dissolve nisin and lysozyme in deionized water at a mass ratio of 2:1 to form Solution C (the total addition amount of Solution C is 3.5% of the mass of Paste B), and disperse Solution C into the uniform Paste B at a pressure of 55 MPa through a high-pressure homogenizer (the nozzle aperture is 0.15 mm, and the homogenization cycle times is 3 times), and let it stand and ripen for 2.5 hours after mixing.

[0043] Inject the ripened paste into a twin-screw extruder (the screw rotation speed is 90 rpm, and the extrusion pressure is 0.9 MPa), and extrude and form at 35°C (the diameter of the extruded paste is 3.5 mm, and the length is cut to 11 cm). After being irradiated with ultraviolet rays of 254 nm wavelength for sterilization for 6 minutes, it is packaged with an aluminum-plastic composite tube (the inner wall of the tube is purged with nitrogen before packaging to isolate oxygen) to obtain dog pet toothpaste.

[0044] Example 5: Formulation:

[0045] Manufacturing process: Add the purified and pretreated food-grade silica, sorbitol solution and xanthan gum in the above formula amounts to a mixing container at a mass ratio of 5:3:1, and stir constantly in a 60°C water bath for 30 minutes to form a homogeneous paste. Add the pretreated sodium lauroyl sarcosinate (mix it with propylene glycol at a mass ratio of 1:2 and heat it to 50°C for dissolution) and the chicken flavor essence and taurine complex (the addition amount is 1.2% of the total mass of the paste), continue to stir and react, and then cool to room temperature to obtain the basic paste A.

[0046] Transfer the basic paste A to a vacuum degassing machine, degas it at a vacuum degree of -0.095 MPa for 35 minutes, and then inject it into an ultrasonic dispersion device (equipped with a spiral flow channel structure, and the paste flow rate during dispersion is controlled at 1.0 L / min), and process it at a frequency of 35 kHz for 18 minutes to obtain a uniform paste B.

[0047] Dissolve nisin and lysozyme in deionized water at a mass ratio of 2:1 to form Solution C (the total addition amount of Solution C is 4.5% of the mass of Paste B), and disperse Solution C into the uniform Paste B at a pressure of 75 MPa through a high-pressure homogenizer (the nozzle aperture is 0.25 mm, and the homogenization cycle times is 4 times), and let it stand and ripen for 3.5 hours after mixing.

[0048] The ripened paste is injected into a twin-screw extruder (screw rotation speed is 110 rpm, extrusion pressure is 1.1 MPa), and extruded into a shape at 45°C (the diameter of the extruded paste is 4.5 mm, and the length is cut to 13 cm). After being irradiated with ultraviolet light of wavelength 254 nm for sterilization for 9 minutes, it is packaged in an aluminum-plastic composite tube (the inner wall of the tube is purged with nitrogen before packaging to isolate oxygen), and the dog toothpaste is obtained.

[0049] Example 6: Formula:

[0050] Manufacturing process: The food-grade silica, sorbitol solution, and xanthan gum after purification pretreatment in the formula amount are added to a mixing container according to a mass ratio of 5:3:1, and stirred at a constant temperature in a 55°C water bath for 25 minutes to form a homogeneous paste. The pretreated sodium lauroyl sarcosinate (mixed with propylene glycol in a mass ratio of 1:2 and heated to 50°C for dissolution), chicken flavor essence, and taurine complex (the addition amount is 1.1% of the total mass of the paste) are added, and stirring and reaction are continued, and then cooled to room temperature to obtain the basic paste A.

[0051] The basic paste A is transferred to a vacuum degassing machine, degassed at a vacuum degree of -0.092 MPa for 32 minutes, and then injected into an ultrasonic dispersion device (equipped with a spiral flow channel structure, and the paste flow rate during dispersion is controlled at 0.7 L / min), and processed at a frequency of 28 kHz for 13 minutes to obtain a uniform paste B.

[0052] Nisin and lysozyme are dissolved in deionized water according to a mass ratio of 2:1 to form solution C (the total addition amount of solution C is 4.2% of the mass of paste B), and solution C is dispersed into the uniform paste B at a pressure of 62 MPa through a high-pressure homogenizer (the nozzle aperture is 0.18 mm, and the homogenization cycle times are 4 times), and after mixing, it is left to ripen for 3.2 hours.

[0053] The ripened paste is injected into a twin-screw extruder (screw rotation speed is 95 rpm, extrusion pressure is 0.95 MPa), and extruded into a shape at 38°C (the diameter of the extruded paste is 3.8 mm, and the length is cut to 11.5 cm). After being irradiated with ultraviolet light of wavelength 254 nm for sterilization for 7 minutes, it is packaged in an aluminum-plastic composite tube (the inner wall of the tube is purged with nitrogen before packaging to isolate oxygen), and the dog toothpaste is obtained.

[0054] Example 7: Formula:

[0055] Manufacturing process: Add food-grade silicon dioxide, sorbitol solution, and xanthan gum in the formula amount to a mixing container in a mass ratio of 5:3:1. Stir constantly in a water bath at 45°C for 32 minutes to form a homogeneous paste. Add pretreated sodium lauroyl sarcosinate (mixed with propylene glycol in a mass ratio of 1:2 and heated to 50°C for dissolution), chicken flavor essence, and taurine complex (the addition amount is 0.9% of the total mass of the paste), continue stirring and reacting, and then cool to room temperature to obtain basic paste A.

[0056] Transfer basic paste A to a vacuum degassing machine and degas it at a vacuum degree of -0.088 MPa for 28 minutes. Then inject it into an ultrasonic dispersion device (equipped with a spiral flow channel structure, and the flow rate of the paste during dispersion is controlled at 0.9 L / min), and process it at a frequency of 32 kHz for 16 minutes to obtain uniform paste B.

[0057] Dissolve nisin and lysozyme in deionized water in a mass ratio of 2:1 to form solution C (the total addition amount of solution C is 3.8% of the mass of paste B), and disperse solution C into uniform paste B at a pressure of 58 MPa through a high-pressure homogenizer (the nozzle aperture is 0.22 mm, and the homogenization cycle times are 3 times). After mixing, let it stand and ripen for 2.8 hours.

[0058] Inject the ripened paste into a twin-screw extruder (the screw rotation speed is 105 rpm, and the extrusion pressure is 1.05 MPa), extrude and form it at 42°C (the diameter of the extruded and formed paste is 4.2 mm, and the length is cut to 12.5 cm). After sterilization by ultraviolet irradiation with a wavelength of 254 nm for 8 minutes, it is packaged in an aluminum-plastic composite tube (the inner wall of the tube is purged with nitrogen before packaging to isolate oxygen) to obtain dog pet toothpaste.

[0059] Comparative Example 1: Formula:

[0060] Manufacturing process: Add the purified and pre-treated food-grade silica, sorbitol solution, and xanthan gum in the above formula amounts to a mixing container in a mass ratio of 5:3:1, and stir at a constant temperature in a 50°C water bath for 30 minutes to form a homogeneous paste. Add the pre-treated sodium lauroyl sarcosinate (mixed with propylene glycol in a mass ratio of 1:2 and heated to 50°C for dissolution), chicken flavor essence, and taurine complex (the addition amount is 0.5% of the total mass of the paste), continue stirring and reacting, and then cool to room temperature to obtain the basic paste A.

[0061] Transfer the basic paste A to a vacuum degassing machine, degas at a vacuum degree of -0.08 MPa for 20 minutes, and then inject it into a general stirring device and stir for 10 minutes to obtain a paste.

[0062] Inject the ripened paste into a twin-screw extruder (the screw rotation speed is 80 rpm, and the extrusion pressure is 0.8 MPa), extrude and form at 30°C (the diameter of the extruded and formed paste is 3 mm, and the length is cut to 10 cm). After irradiating and sterilizing with ultraviolet light of wavelength 254 nm for 5 minutes, package it with an aluminum-plastic composite tube (the inner wall of the tube is purged with nitrogen before packaging to isolate oxygen) to obtain the dog pet toothpaste. In this comparative example, no antibacterial agent and natural enzyme preparation were added, and no ultrasonic dispersion equipment was used.

[0063] Comparative Example 2: Formula:

[0064] Manufacturing process: Add the purified and pre-treated food-grade silica, sorbitol solution, and xanthan gum in the above formula amounts to a mixing container in a mass ratio of 5:3:1, and stir at a constant temperature in a 50°C water bath for 30 minutes to form a homogeneous paste. Add the pre-treated sodium lauroyl sarcosinate (mixed with propylene glycol in a mass ratio of 1:2 and heated to 50°C for dissolution), chicken flavor essence, and taurine complex (the addition amount is 0.5% of the total mass of the paste), continue stirring and reacting, and then cool to room temperature to obtain the basic paste A.

[0065] Transfer the basic paste A to a vacuum degassing machine, degas at a vacuum degree of -0.08 MPa for 20 minutes, and then inject it into an ultrasonic dispersion device (equipped with a spiral flow channel structure, and the flow rate of the paste during dispersion is controlled at 0.5 L / min), and process it at a frequency of 20 kHz for 10 minutes to obtain a uniform paste B.

[0066] Dissolve nisin in deionized water to form Solution C (the total addition amount of Solution C is 3% of the mass of Paste B), and disperse Solution C into the homogeneous Paste B through ordinary stirring equipment. After mixing, let it stand and ripen for 2 hours.

[0067] Inject the ripened paste into a twin-screw extruder (screw rotation speed is 80 rpm, extrusion pressure is 0.8 MPa), and extrude and form at 30°C (the diameter of the extruded paste is 3 mm, and the length is cut to 10 cm). After irradiating and sterilizing with ultraviolet light of wavelength 254 nm for 5 minutes, package it with an aluminum-plastic composite tube (the inner wall of the tube is purged with nitrogen before packaging to isolate oxygen) to obtain dog pet toothpaste. In this comparative example, lysozyme was not added, and a high-pressure homogenizer was not used to disperse Solution C.

[0068] Comparative Example 3: Formulation:

[0069] Manufacturing process: Add the purified and pretreated food-grade silica, sorbitol solution, and xanthan gum in the above formulation amounts to a mixing container according to a mass ratio of 5:3:1, and stir at a constant temperature in a 50°C water bath for 30 minutes to form a homogeneous paste. Add the pretreated sodium lauroyl sarcosinate (mix it with propylene glycol at a mass ratio of 1:2 and heat to 50°C for dissolution), chicken flavor essence, and taurine complex (the addition amount is 0.5% of the total mass of the paste), continue stirring and reacting, and then cool to room temperature to obtain Base Paste A.

[0070] Inject Base Paste A directly into a twin-screw extruder (screw rotation speed is 80 rpm, extrusion pressure is 0.8 MPa), and extrude and form at 30°C (the diameter of the extruded paste is 3 mm, and the length is cut to 10 cm). After irradiating and sterilizing with ultraviolet light of wavelength 254 nm for 5 minutes, package it with an aluminum-plastic composite tube (the inner wall of the tube is purged with nitrogen before packaging to isolate oxygen) to obtain dog pet toothpaste. In this comparative example, vacuum degassing and ultrasonic dispersion treatments were not carried out, and a high-pressure homogenizer was not used to disperse the antibacterial agent and natural enzyme preparation solution.

[0071] Comparative Example 4: Formulation:

[0072] Manufacturing process: Add the purified and pre-treated food-grade silica, sorbitol solution and xanthan gum in the above formula amounts to a mixing container in a mass ratio of 5:3:1, and stir at a constant temperature in a 50°C water bath for 30 minutes to form a homogeneous paste. Then add the pre-treated sodium lauroyl sarcosinate (mixed with propylene glycol in a mass ratio of 1:2 and heated to 50°C for dissolution), chicken flavor essence and taurine complex (the addition amount is 0.5% of the total mass of the paste), as well as benzoic acid, continue stirring and reacting, and then cool to room temperature to obtain the basic paste A.

[0073] Transfer the basic paste A to a vacuum degassing machine, degas at a vacuum degree of -0.08 MPa for 20 minutes, and then inject it into an ultrasonic dispersion device (equipped with a spiral flow channel structure, and the paste flow rate during dispersion is controlled at 0.5 L / min), and process it at a frequency of 20 kHz for 10 minutes to obtain a uniform paste B.

[0074] Dissolve nisin and lysozyme in deionized water in a mass ratio of 2:1 to form solution C (the total addition amount of solution C is 3% of the mass of paste B), and disperse solution C into the uniform paste B at a pressure of 50 MPa through a high-pressure homogenizer (the nozzle aperture is 0.1 mm, and the homogenization cycle times is 3 times), and let it stand and ripen for 2 hours after mixing.

[0075] Inject the ripened paste into a twin-screw extruder (the screw rotation speed is 80 rpm, and the extrusion pressure is 0.8 MPa), extrude and form at 30°C (the diameter of the extruded and formed paste is 3 mm, and the length is cut to 10 cm), irradiate with ultraviolet light of wavelength 254 nm for sterilization for 5 minutes, and then package with an aluminum-plastic composite tube (the inner wall of the tube is purged with nitrogen before packaging to isolate oxygen) to obtain dog toothpaste. This comparative example uses benzoic acid to replace part of the antibacterial components to observe the impact on the toothpaste performance.

[0076] Comparative Example 5: Formula:

[0077] Manufacturing process: Add the purified and pre-treated food-grade silica, calcium carbonate, sorbitol solution and xanthan gum in the above formula amounts to a mixing container in a certain ratio, and stir at a constant temperature in a 50°C water bath for 30 minutes to form a homogeneous paste. Then add the pre-treated sodium lauroyl sarcosinate (mixed with propylene glycol in a mass ratio of 1:2 and heated to 50°C for dissolution), chicken flavor essence and taurine complex (the addition amount is 0.5% of the total mass of the paste), continue stirring and reacting, and then cool to room temperature to obtain the basic paste A.

[0078] The subsequent steps are the same as steps 2 - 4 in Example 1, and a dog pet toothpaste is obtained. In this comparative example, calcium carbonate is used to replace part of the food-grade silica as the abrasive to compare the influence of different abrasives on the use effect of the toothpaste.

[0079] Toothpaste performance detection: The dog pet toothpastes prepared in the above examples and comparative examples were subjected to performance detection, and the results are shown in the following table:

[0080] It can be seen from the above examples and comparative examples that the formula and production process of the dog pet toothpaste described in the present invention have significant advantages in antibacterial performance, paste stability, palatability, cleaning effect, etc. The reasonable combination of each component and the specific production process steps effectively improve the overall performance of the toothpaste.

[0081] Antibacterial performance: The antibacterial rates of the toothpastes in Examples 1 - 7 against common oral bacteria all reached 92% or above, while the antibacterial rates of Comparative Examples 1 - 5 were all lower than 90%. Among them, in Comparative Example 1, no antibacterial agent and natural enzyme preparation were added, and the antibacterial rate was only 75%; in Comparative Example 4, benzoic acid was used to replace part of the antibacterial components, and the antibacterial rate was 85%. This shows that the combination of nisin and lysozyme adopted in the present invention, as well as the specific addition process, can significantly improve the antibacterial ability of the toothpaste and effectively inhibit the growth of bacteria in the dog's oral cavity.

[0082] Paste stability: After being placed at room temperature for 3 months, the toothpastes of all examples showed no stratification or caking phenomenon and had good stability; a small amount of caking occurred in Comparative Example 3, and slight stratification occurred in Comparative Example 1. This shows that through process steps such as vacuum defoaming, ultrasonic dispersion, and high-pressure homogenization, the present invention ensures the uniform dispersion of each component, effectively improves the stability of the paste, and guarantees the product quality.

[0083] Palatability: The palatability scores of the toothpastes in the examples were all 8.0 or above, while the scores of the comparative examples were all lower than 8.0. The changes in the composition or process of Comparative Examples 1 - 5 led to a decrease in the attractiveness of the toothpaste to dogs in terms of smell, taste, etc. This shows that the complex of chicken flavor essence and taurine in the present invention, as well as the reasonable combination of the overall formula, greatly improves the palatability of the toothpaste and makes it easier for dogs to accept the use.

[0084] Cleaning effect: The cleaning effect scores of the toothpastes in the examples are all 7.8 points and above, while those of the comparative examples are all lower than 7.8 points. In Comparative Example 5, calcium carbonate was used to replace part of the food-grade silica as the abrasive, and the cleaning effect score was only 7.0 points. This shows that the food-grade silica used in the present invention as the abrasive, combined with a specific production process, can better play the cleaning role, effectively remove the stains on the surface of canine teeth, and maintain oral hygiene.

[0085] In summary, the formula and production process of the canine pet toothpaste described in the present invention are superior to the products of the comparative examples in terms of antibacterial performance, paste stability, palatability, and cleaning effect through the scientific ratio of each component and the unique production process, showing significant advantages and good application prospects.

[0086] Although the embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principles and spirit of the present invention. All equivalent changes and improvements made within the scope of the application of the present invention shall still fall within the scope covered by the patent of the present invention.

Claims

1. A manufacturing process of a dog pet toothpaste, characterized in that, It includes the following steps: S1: Add the purified and pretreated friction agent, humectant and binder into a mixing container according to a certain mass ratio, stir at a constant temperature in a water bath at 40 - 60 °C until a homogeneous paste is formed, add the pretreated foaming agent and flavoring agent, continue stirring and reacting, and then cool to room temperature to obtain the basic paste A; S2: Transfer the basic paste A to a vacuum degassing machine, degas at a vacuum degree of -0.08 to -0.1 MPa for 20 - 40 minutes, and then inject it into an ultrasonic dispersion device, and process it at a frequency of 20 - 40 kHz for 10 - 20 minutes to obtain a uniform paste B; S3: Dissolve the antibacterial agent and natural enzyme preparation in deionized water according to a ratio to form solution C, and disperse solution C into the uniform paste B with a pressure of 50 - 80 MPa through a high-pressure homogenizer, and let it stand and ripen for 2 - 4 hours after mixing; S4: Inject the ripened paste into a twin-screw extruder, extrude and form it at 30 - 50 °C, sterilize it by ultraviolet irradiation, and then package it to obtain the dog toothpaste.

2. The manufacturing process of a dog toothpaste according to claim 1, wherein the friction agent described in S1 is food-grade silica, the humectant described in S1 is sorbitol solution, and the binder described in S1 is xanthan gum; the certain mass ratio described in S1 is that the ratio of the friction agent: humectant: binder = 5:3:1; the constant temperature stirring condition described in S1 is stirring in a 50 °C water bath for 30 minutes.

3. The manufacturing process of a dog toothpaste according to claim 2, wherein the pretreated foaming agent described in S1 is sodium lauroyl sarcosinate, and the pretreatment method is to mix it with propylene glycol according to a mass ratio of 1:2 and heat it to 50 °C for dissolution; the flavoring agent described in S1 is a complex of chicken flavor essence and taurine, and the addition amount is 0.5 - 1.5% of the total mass of the paste.

4. The manufacturing process of a dog toothpaste according to claim 1, wherein the ultrasonic dispersion device described in S2 is provided with a spiral flow channel structure, and the flow rate of the paste during the dispersion process is controlled at 0.5 - 1.2 L / min.

5. The manufacturing process of a dog toothpaste according to claim 1, wherein the antibacterial agent described in S3 is nisin, and the natural enzyme preparation is lysozyme; the dissolution according to the ratio described in S3 has a mass ratio of antibacterial agent: natural enzyme preparation = 2:1, and the total addition amount of solution C is 3 - 5% of the mass of paste B.

6. The manufacturing process of a dog toothpaste according to claim 1, wherein the screw rotation speed of the twin-screw extruder described in S4 is 80 - 120 rpm, and the extrusion pressure is 0.8 - 1.2 MPa; the wavelength of the ultraviolet irradiation sterilization described in S4 is 254 nm, and the irradiation time is 5 - 10 minutes.

7. The manufacturing process of a canine pet toothpaste as described in claim 6, characterized in that, The diameter range of the extruded and formed paste is 3 - 5 mm, and the length is cut to 10 - 15 cm.

8. The manufacturing process of a dog toothpaste according to claim 7, wherein the packaging described in S4 uses an aluminum-plastic composite tube, and the inner wall of the tube is purged with nitrogen before packaging to isolate oxygen.

9. The manufacturing process of a canine pet toothpaste as claimed in claim 5, wherein the nozzle aperture of the high-pressure homogenizer described in S3 is 0.1 - 0.3 mm, and the number of homogenization cycles is 3 - 5 times.

10. A formula for canine pet toothpaste, characterized in that, comprises the following components by mass percentage: 10 - 15% of food-grade silica, 8 - 12% of sorbitol solution, 2 - 4% of xanthan gum, 1 - 3% of sodium lauroyl sarcosinate, 0.3 - 0.8% of chicken flavor essence, 0.2 - 0.5% of taurine, 0.1 - 0.3% of nisin, 0.05 - 0.15% of lysozyme, and the balance of deionized water.

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