Composite scalp care composition, application thereof and daily chemical product

Abstract

The invention belongs to the technical field of daily chemical products, and discloses a composite scalp care composition which is composed of a hydrolyzed rice protein solution, a hydrolyzed silk protein solution, a wrapped salicylic acid solution and an arginine glycerin derivative solution. The mass ratio of the hydrolyzed rice protein solution to the hydrolyzed silk protein solution to the wrapped salicylic acid solution to the arginine glycerin derivative is (10-65): (10-65): (5-60): (20-75). Through the synergistic interaction of the four components, the composite scalp care composition can improve the water content of scalp, repair the sebum film barrier, gently metabolize grease and cutin, maintain smooth pores and stable micro-ecology, achieve excellent moisturizing, anti-allergy and soothing effects, remarkably reduce the irritation to sensitive scalp, and improve the skin care effect. The tenderness and the functional stability of the whole formula are improved. Meanwhile, the invention further discloses application and daily chemical products of the composite scalp care composition.

Description

Technical Field

[0001] The present invention belongs to the technical field of cosmetics, and discloses a composite scalp care composition, its application, and a daily chemical product. Background Art

[0002] With the improvement of people's living standards and the increasing emphasis on personal image, scalp care has gradually become a key area of concern for consumers. A healthy scalp is not only the basis for strong and shiny hair but also closely related to an individual's overall sense of comfort. However, in modern life, the scalp faces many challenges. On the one hand, environmental factors such as air pollution, ultraviolet radiation, and climate change continuously damage the scalp. Pollutant particles in the air are easily attached to the scalp surface, clogging hair follicles and affecting the normal respiration and metabolism of the scalp; high-intensity ultraviolet radiation can damage the scalp's barrier function, leading to increased water loss; seasonal temperature and humidity changes can also make the scalp condition unstable, prone to discomfort symptoms such as dryness and itching. On the other hand, bad living habits and frequent hair styling operations further exacerbate scalp problems. Staying up late and being under excessive mental stress for a long time can interfere with the endocrine system, affect the balance of scalp sebum secretion, and thus trigger scalp inflammation; frequent hair styling treatments such as hair dyeing, perming, and straightening, the chemical agents used will directly contact the scalp, damage the cutin layer of the scalp, reduce the scalp's self-repair ability, and make the scalp become sensitive and fragile.

[0003] At present, there are a variety of scalp care products on the market, but most products have limitations in function. Common moisturizing products mainly rely on traditional moisturizers such as glycerin and sodium hyaluronate. Although they can relieve scalp dryness to a certain extent, the moisturizing effect lasts for a short time and cannot fundamentally improve the scalp's moisturizing ability. For the soothing and anti-allergic function, some products add simple plant extracts. However, the concentration of these ingredients in the formula is low and the action mechanism is single, making it difficult to effectively cope with complex and diverse scalp allergic and inflammatory reactions. In addition, some oil-control ingredients may be irritating to the scalp, causing allergic and other adverse reactions and are not suitable for people with sensitive scalps.

[0004] Therefore, the technical problem to be solved by the present invention is how to develop a composite scalp care composition with long-acting moisturizing, barrier repair, mild purification, and soothing conditioning functions, which can not only increase the water content of the scalp, repair the sebum membrane barrier, but also gently metabolize oil and cutin, maintain smooth pores and microecological stability, and is suitable for the sensitive scalp group, with good skin tolerance and low irritation. Summary of the Invention

[0005] The object of the present invention is to provide a composite scalp care composition, which is composed of a hydrolyzed rice protein solution, a hydrolyzed silk protein solution, a encapsulated salicylic acid solution and an arginine glycerol derivative solution. Through the synergistic effect among the four components, the composite scalp care composition can not only improve the water content of the scalp and repair the sebum membrane barrier, but also gently metabolize oil and cutin, maintain smooth pores and stable microecology, achieve excellent moisturizing, anti-allergic and soothing effects, and significantly reduce the irritation to sensitive scalps, improving the mildness and functional stability of the overall formulation.

[0006] Meanwhile, the present invention also provides the use of the composite scalp care composition and daily chemical products.

[0007] To achieve the above object, the present invention provides the following technical solutions:

[0008] A composite scalp care composition, the composite scalp care composition is composed of a hydrolyzed rice protein solution, a hydrolyzed silk protein solution, encapsulated salicylic acid and an arginine glycerol derivative solution, and the mass ratio of the hydrolyzed rice protein solution, the hydrolyzed silk protein solution, encapsulated salicylic acid and the arginine glycerol derivative solution is 10-65:10-65:5-60:20-75.

[0009] Preferably, the arginine glycerol derivative solution contains 30wt% of dihydroxypropyl arginine hydrochloride, and the arginine glycerol derivative has the structural formula shown in Formula I;

[0010]

[0011] The arginine glycerol derivative forms an oriented adsorption layer on the scalp surface through cationic anchoring technology (synergy of hydrogen bond + ionic bond), improves the water content of the stratum corneum, and constructs a chemical moisturizing barrier. Its strong cationic property enables it to maintain strong adsorption even after rinsing, achieving ultra-long moisturization. As the core component for basic moisturization and barrier repair, it lays the foundation for the scalp's moisturizing barrier, making subsequent components more easily penetrate and play their roles.

[0012] The hydrolyzed rice protein solution contains 25wt% of hydrolyzed rice protein;

[0013] The hydrolyzed rice protein is rich in moisturizing amino acids such as glutamic acid and alanine, can penetrate into the hair and the stratum corneum of the scalp, supplement natural moisturizing factors (NMF) for them, provide essential protein repair for the hair, supplement hair moisture, enhance the flexibility and anti-breakage of the hair, and form a synergistic moisturizing system with the arginine glycerol derivative. On the one hand, it improves the scalp hydration environment, and on the other hand, it enhances the water content and strength of the hair shaft, reducing dandruff and hair fragility caused by dryness.

[0014] The hydrolyzed silk protein solution contains 6.5wt% of hydrolyzed silk;

[0015] Hydrolyzed silk protein can form a natural water-locking film on the hair surface, playing a role in softening and smoothing. It also has a certain nourishing and barrier-strengthening effect on the scalp, reducing water evaporation and external stimuli. It forms a "three-layer moisture system" with hydrolyzed rice protein and arginine glycerol derivative: osmotic water replenishment (rice protein), water-locking and stability maintenance (silk protein), and barrier enhancement (arginine glycerol derivative), forming a "skin-like repair barrier film" for the scalp and hair.

[0016] Preferably, the encapsulated salicylic acid solution contains 32.5 wt% encapsulated salicylic acid. The shell material of the encapsulated salicylic acid is cocamidopropyl dimethylamine, and the content of the shell material is 22.5 wt%, and the content of salicylic acid encapsulated in the shell material is 10 wt%.

[0017] Through the encapsulation technology, the irritation of salicylic acid is reduced, the barrier is not damaged and no sensitization occurs. Its role in the whole system is to provide mild conditioning and microecological regulation functions. By dredging pores and antibacterial (against anaerobic bacteria) effects, follicle blockage is avoided, and sebum secretion is regulated, providing a cleaner penetration channel for moisturizing ingredients.

[0018] In the present invention, hydrolyzed rice protein, hydrolyzed silk protein, encapsulated salicylic acid and arginine glycerol derivative have a synergistic effect, and its possible mechanism is as follows:

[0019] Both hydrolyzed rice protein and hydrolyzed silk protein contain rich carboxyl groups and amino acid residues, which can form hydrogen bonds and weak ionic bond interactions with the glycerol group and arginine of arginine glycerol derivative; such physical binding can form a "amino acid network structure film" on the surface of scalp cutin, improving film-forming property and moisturizing property; further forming a three-dimensional multi-dimensional hydrated structure of "osmotic water replenishment, film-forming water locking, and ionic layer attachment", so as to achieve the effects of prolonging the moisturizing persistence, enhancing barrier repair, and reducing dry dandruff.

[0020] Hydrolyzed rice protein and hydrolyzed silk protein are rich in carboxyl and hydroxyl groups with negative charges or polarities, and electrostatic and hydrogen bond binding occur with the cationic outer shell cocamidopropyl dimethylamine of encapsulated salicylic acid. On the scalp surface, the cationic outer shell associates with the protein to form a semi-permeable protective film layer, prolonging the release period of salicylic acid. The protein-outer shell film can buffer the acidic environment during the micro-release of salicylic acid, and endow the scalp with a smooth feel, soothe the irritation, thus significantly reducing the irritation to sensitive scalp and improving the mildness and functional stability of the overall formula.

[0021] In addition, the present invention provides the use of the composite scalp care composition as described above for preparing daily chemical products.

[0022] Finally, the present invention discloses a daily chemical product, which contains 0.1-30 wt% of the composite scalp care composition as described above.

[0023] Preferably, the daily chemical product is lotion, cream, spray, essence, or gel.

[0024] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0025] The present invention is composed of a hydrolyzed rice protein solution, a hydrolyzed silk protein solution, a wrapped salicylic acid solution, and an arginine glycerol derivative solution. Through the synergistic effect among the four components, the composite scalp care composition can not only improve the water content of the scalp, repair the sebum membrane barrier, but also gently metabolize oil and cutin, maintain the pore patency and microecological stability, achieving excellent moisturizing, anti-allergic, and soothing effects, and significantly reducing the irritation to sensitive scalps, improving the mildness and functional stability of the overall formula. Detailed Embodiments

[0026] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0027] Product Information:

[0028] Wrapped salicylic acid solution: The trade name is SalSphere Skin Smoothing, purchased from (Dongfeng Chemical (Hangzhou) Co., Ltd.), containing 22.5 wt% cocamidopropyl dimethylamine, 10 wt% salicylic acid, 0.85 wt% phenoxyethanol, 0.14 wt% ethylhexylglycerol, and the balance water.

[0029] Arginine glycerol derivative solution: The trade name is Amitose R, purchased from Chenghe Cosmetics Chemicals (Shanghai) Co., Ltd., which includes, by mass percentage: 30 wt% dihydroxypropyl arginine hydrochloride, 1 wt% phenoxyethanol, and the balance water.

[0030] Hydrolyzed rice protein solution: The trade name is Promois WR, purchased from Chenghe Cosmetics Chemicals (Shanghai) Co., Ltd., which includes, by mass percentage: 25 wt% hydrolyzed rice protein, 3% butanediol, 1% phenoxyethanol, and the balance water.

[0031] Hydrolyzed silk protein solution: The trade name is Promois SILK-1000F, purchased from Chenghe Cosmetics Chemicals (Shanghai) Co., Ltd., which includes by mass percentage: 6.5 wt% hydrolyzed silk, 5 wt% butanediol, 1 wt% phenoxyethanol, and the balance is water.

[0032] Examples

[0033] The formulation tables of the composite scalp care compositions of each example and comparative example are shown in Table 1;

[0034] Table 1 Formulation Table of Composite Scalp Care Composition (parts by mass)

[0035]

[0036] The compositions obtained in the above examples and comparative examples were made into scalp essences according to the formulation in Table 2. The specific steps are as follows:

[0037] 1. After neutralizing and dissolving the raw materials in Phase B until transparent, add Phase A;

[0038] 2. Add Phase C;

[0039] 3. Find a suitable container, heat the raw materials in Phase D to 60 - 70 °C until dissolved and transparent, and then add;

[0040] 4. Add the raw materials in Phase E in sequence and stir until uniform;

[0041] 5. Add the raw materials in Phase F and stir evenly.

[0042] Table 2 Formulation Table of Scalp Essence

[0043]

[0044] The essences corresponding to Examples 1 to 3 are Essence 1 to Essence 3, and the essences corresponding to Comparative Examples 1 to 4 are Essence 4 to Essence 7.

[0045] Performance Detection

[0046] Scalp Condition Test

[0047] The cosmetic irritation of each prepared scalp essence was evaluated. The test method was the scalp condition test. 35 people aged 16 - 65 with scalp itching, redness, and excessive sebum secretion were tested, and the number of test people in each group was 5.

[0048] Test method: Observe the scalp condition on the 0th day and take scalp photos. Use the scalp essence once a day for 4 consecutive weeks, then observe and take photos again. Score according to your own condition. The evaluation dimensions are scalp itching, scalp dryness, scalp redness, scalp oiliness, scalp odor, and dandruff. The score is divided into 5 levels: very uncomfortable (1 point), slightly uncomfortable (2 points), medium (3 points), significantly improved (4 points), and completely improved (5 points), and then calculate the total score.

[0049] Table 3 Test results of scalp conditions

[0050] Sample source Scalp condition score Essence 1 4.9 Essence 2 4.1 Essence 3 4.5 Essence 4 2.6 Essence 5 2.8 Essence 6 1.9 Essence 7 2.4

[0051] Based on the scalp condition scores in Table 3, Essence 1 - 3 have relatively high scores, all greater than 4.0, showing a significant improvement effect. Among them, the score of Essence 1 is as high as 4.9; while in the compositions of Essence 4 - 7, one or two components are missing, and their scores have dropped significantly. This indicates that the composition of the technical solution of the present invention is safe and non - irritating to the scalp, and the four components in the composition have a synergistic effect, which can significantly improve problems such as scalp redness, oiliness, and odor.

[0052] Measurement of stratum corneum water content

[0053] Men and women aged 20 - 30 are used as experimental subjects, with 5 people in each test group. Use it twice a day for 14 consecutive days, and then use Corneometer CM - 825 (Courage+Khazaka electronic GmbH) to measure the stratum corneum water content of the scalp before and after use; the test results are shown in Table 4.

[0054] Table 4 Change rate of stratum corneum water content

[0055] Sample source Rate of change in stratum corneum water content % Essence 1 43.45 Essence 2 38.12 Essence 3 40.02 Essence 4 27.98 Essence 5 29.65 Essence 6 15.47 Essence 7 25.21

[0056] From the data analysis in Table 4, in terms of the change rate of stratum corneum water content, Essence 1 - 3 have relatively high change rates. Among them, the change rate of Essence 1 is 43.45%, indicating that the essence prepared from the composite scalp care composition of the present invention has excellent moisturizing performance;

[0057] The composition of Essences 4 and 5 lacks the encapsulated salicylic acid solution or arginine glycerol derivative solution, and the change rate of the water content in the stratum corneum is about 28%. Essence 6 lacks both the hydrolyzed rice protein solution and the hydrolyzed silk protein solution at the same time, and Essence 7 lacks both the encapsulated salicylic acid solution and the arginine glycerol derivative solution at the same time. In these two cases, the change rate of the water content in the stratum corneum is further reduced to 15%-26%, indicating that its moisturizing effect is poor. The above data shows that the four components in the composite scalp care composition of the present invention are all indispensable, and when the four components are used together, they have the effect of synergistically increasing the water content of the scalp stratum corneum.

[0058] Hyaluronidase inhibition rate

[0059] Hyaluronidase is a hydrolase of hyaluronic acid, which is closely related to the occurrence of inflammation and allergy and plays a corresponding role in anti-allergy. Research shows that some anti-allergy drugs have strong inhibition on the activity of hyaluronidase, so the inhibition of hyaluronidase activity can be used as an index for anti-allergy effect.

[0060] The hyaluronidase inhibition rate is used to judge whether the test sample has a soothing effect. The higher the hyaluronidase inhibition rate of the test sample, the better the soothing effect of the test sample.

[0061] Prepare a sample solution with the essence at a concentration of 25%. In several sample solution tubes with different concentrations, add an appropriate concentration of hyaluronidase solution and sodium hyaluronate solution respectively. After shaking each tube well, add anhydrous ethanol and let it stand at room temperature for 30 min. Measure the absorbance value at 530 nm with an enzyme-linked immunosorbent assay (ELISA) reader and calculate the hyaluronidase inhibition rate.

[0062] Table 5 Hyaluronidase inhibition rate

[0063] Sample source Hyaluronidase inhibition rate % Essence 1 61.37 Essence 2 56.03 Essence 3 53.26 Essence 4 44.30 Essence 5 41.08 Essence 6 19.57 Essence 7 33.12

[0064] From the data in Table 5, it can be seen that in terms of the hyaluronidase inhibition rate, Essences 1-3 all have a relatively high hyaluronidase inhibition rate, between 53%-62%, indicating that they have a good soothing effect. The composition of Essences 4 and 5 lacks the encapsulated salicylic acid solution or arginine glycerol derivative solution, and its hyaluronidase inhibition rate is between 41%-45%. Essence 6 lacks both the hydrolyzed rice protein solution and the hydrolyzed silk protein solution at the same time, and Essence 7 lacks both the encapsulated salicylic acid solution and the arginine glycerol derivative solution at the same time. In these two cases, the hyaluronidase inhibition rate is further reduced to 19%-34%, indicating that its soothing effect is poor. The above data shows that the four components in the composite scalp care composition of the present invention are all indispensable, and when the four components are used together, they have the effect of synergistically increasing the hyaluronidase inhibition rate.

[0065] In summary, there is a synergistic effect among the four components in the composite scalp care composition of the present invention, and its mechanism may be as follows: Both hydrolyzed rice protein and hydrolyzed silk protein contain rich carboxyl groups and amino acid residues, which can form hydrogen bonds and weak ionic bond interactions with the glycerol group and arginine of arginine glycerol derivatives; such physical binding can form a "amino acid network structure film" on the surface of scalp cutin, improving the film-forming property and moisture retention; further forming a three-dimensional hydrated structure of "penetrating water replenishment, film-forming water locking, and ion layer attachment", so as to achieve the effects of prolonging the moisture retention duration, enhancing barrier repair, and reducing dry dandruff. Hydrolyzed rice protein and hydrolyzed silk protein are rich in negatively charged or polar groups such as carboxyl and hydroxyl groups, which electrostatically and hydrogen-bond with the cationic outer shell cocamidopropyl dimethylamine encapsulating salicylic acid. On the scalp surface, the cationic outer shell associates with the protein to form a semi-permeable protective film layer, prolonging the release period of salicylic acid. The protein-outer shell film can buffer the acidic environment during the micro-release of salicylic acid, and endow the scalp with a smooth feel and soothe the irritation, thus significantly reducing the irritation to sensitive scalps and improving the mildness and functional stability of the overall formulation.

[0066] For those skilled in the art, it is obvious that the present invention is not limited to the details of the above exemplary embodiments, and without departing from the spirit or basic characteristics of the present invention, the present invention can be implemented in other specific forms. Therefore, from any point of view, the embodiments should be regarded as exemplary and non-limiting. The scope of the present invention is defined by the appended claims rather than the above description. Therefore, all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be included in the present invention.

Claims

1. A composite scalp care composition, characterized in that, The described composite scalp care composition is composed of a hydrolyzed rice protein solution, a hydrolyzed silk protein solution, an encapsulated salicylic acid solution, and an arginine glycerol derivative solution. The mass ratio of the hydrolyzed rice protein solution, the hydrolyzed silk protein solution, the encapsulated salicylic acid solution, and the arginine glycerol derivative is 10 - 65:10 - 65:5 - 60:20 - 75.

2. The composite scalp care composition according to claim 1, characterized in that, The arginine glycerol derivative solution contains 30 wt% of dihydroxypropyl arginine hydrochloride, and the arginine glycerol derivative has the structural formula shown in Formula I; The hydrolyzed rice protein solution contains 25 wt% of hydrolyzed rice protein; The hydrolyzed silk protein solution contains 6.5 wt% of hydrolyzed silk; The encapsulated salicylic acid solution contains 32.5 wt% of encapsulated salicylic acid. The shell material of the encapsulated salicylic acid is coconut oil amide propyl dimethylamine, and the content of the shell material is 22.5 wt%, and the content of salicylic acid encapsulated in the shell material is 10 wt%.

3. Use of the composite scalp care composition according to any one of claims 1 or 2 for preparing a daily chemical product.

4. A daily chemical product, characterized in that The daily chemical product contains 0.1 - 30 wt% of the composite scalp care composition according to any one of claims 1 or 2.

5. The scalp oil control composition according to claim 4, characterized in that The daily chemical product is an emulsion, a cream, a spray, a serum, or a gel.

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