Pathological section dyeing equipment

Abstract

The invention discloses pathological section dyeing equipment, and relates to the technical field of pathological section dyeing. The device comprises an XY-axis driving assembly and a cleaning tank arranged at the bottom of the XY-axis driving assembly, a dropping device is arranged on the XY-axis driving assembly and comprises a shell, a switching assembly is arranged in the shell, four sets of liquid dropping assemblies are evenly distributed on the periphery of the switching assembly, and different dyeing reagents are arranged in a liquid storage bin of each set of liquid dropping assembly; a quantity control assembly is arranged at the bottom of the switching assembly; the switching assembly comprises a connecting shaft, the bottom end of the connecting shaft is fixedly connected with the top end of a lead screw, the peripheral side face of the lead screw is in threaded connection with a movable bearing, the outer side of the movable bearing is movably connected with an installation kit, the outer portion of the installation kit is movably connected with four liquid dropping assemblies, and only one liquid dropping assembly is started for liquid dropping every time liquid dropping is conducted. According to the invention, the dropwise adding amount of the staining reagent can be accurately controlled, so that the staining accuracy of the section can be improved, and the waste of the staining reagent is reduced.

Description

Technical Field

[0001] The present invention belongs to the technical field of pathological section staining, and particularly relates to a pathological section staining device. Background Technique

[0002] A pathological section refers to taking a certain size of diseased tissue, making a pathological section by pathological histology methods, and further examining the lesion with a microscope. The occurrence and development process of the lesion are finally used to make a pathological diagnosis. During the section-making process, part of the diseased tissue or organ is processed through various chemicals and embedding methods to make it fixed and hardened, cut into thin slices on a microtome, adhered to a glass slide, stained with various colors, and examined under a microscope to observe pathological changes and make a pathological diagnosis to provide assistance for clinical diagnosis and treatment. Staining the pathological section is an essential step.

[0003] Currently, during the process of staining pathological sections, it is usually manually stained. First, the paraffin section is dewaxed with xylene, rehydrated with gradient alcohol to distilled water, then hematoxylin is dropped to stain the cell nucleus, and the impregnation time is about 5 - 10 minutes. After the cell nucleus is stained, it becomes dark blue. Subsequently, differentiation and bluing are carried out, and then eosin is dropped to stain the cytoplasm. After impregnation for 1 - 3 minutes, the cytoplasm becomes pink. Finally, the section is dehydrated and sealed to complete the entire staining process of the section. However, xylene in the staining reagent is a toxic substance with certain volatility. Always exposed to the air, there is a certain safety hazard for the operating staff who are too close. At the same time, mistakes are inevitable when dropping the staining reagent, and the dropping amount of the reagent cannot be accurately controlled. Manual staining has low efficiency and is prone to errors.

[0004] The existing pathological section staining is carried out by manual staining. Manual staining has low efficiency and is prone to accidents. The staining reagent has certain toxicity, and at the same time, the dropping amount of the staining agent cannot be accurately controlled. Therefore, the present invention proposes a pathological section staining device. Summary of the Invention

[0005] The purpose of the present invention is to provide a pathological section staining device to solve the problems that the existing pathological section staining is carried out by manual staining, with low efficiency, prone to accidents, the staining reagent has certain toxicity, and at the same time, the dropping amount of the staining agent cannot be accurately controlled.

[0006] To solve the above technical problems, the present invention is realized through the following technical solutions:

[0007] The present invention is a pathological section staining device, comprising an XY axis driving component and a cleaning tank arranged at the bottom of the XY axis driving component, wherein a dripping device is arranged on the XY axis driving component, wherein the dripping device comprises a shell, wherein a switching component is arranged inside the shell, wherein four groups of dripping components are evenly distributed around the switching component, wherein different staining reagents are arranged inside a liquid storage bin of each group of dripping components; wherein a quantity control component is arranged at the bottom of the switching component, wherein the inside of the cleaning tank is used to contain distilled water for washing away excess staining reagents on a section glass slide, wherein the shell is used to protect each component inside, and the inside of the liquid storage bin is used to load staining reagents;

[0008] The switching assembly includes a connecting shaft, the bottom end of the connecting shaft is fixedly connected to the top end of the screw rod, the side surface of the screw rod is threadedly connected with a movable bearing, the outer side of the movable bearing is movably connected with an installation kit, the outside of the installation kit is movably connected to four groups of dripping assemblies, and each time only one group of dripping assemblies is started to drip; the connecting shaft is used to connect the switching motor and the screw rod, and when the movable bearing on the screw rod moves to the top of the screw rod, the movable bearing continues to move upward to the bottom of the side surface of the connecting shaft, and when the connecting shaft continues to rotate, it will not affect the lifting and lowering of the movable bearing; the installation kit is installed on the outer surface of the movable bearing, and is used to connect with the dripping assembly;

[0009] The drip assembly includes a movable plate, one end of the telescopic shaft above the movable plate is opposite to a circular groove provided on the outside of the installation kit, and the telescopic shaft is movably arranged inside the circular groove, the bottom of the movable plate is connected to one end of the connecting arm through a first movable member, the other end of the connecting arm is welded to the top of the pedestal through a second movable member, a rubber sleeve is fixedly connected to the bottom of the pedestal, a dropper is connected and penetrated at the bottom end of the rubber sleeve, the dripping port at the bottom end of the dropper is located directly above the slice glass placed on the staining table, the movable plate rises and falls driven by the switching assembly, only one movable plate rises and falls at a time, and when a group of drip assemblies is When the telescopic shaft is inserted into one of the circular grooves of the installation kit, the screw rod rotates to drive the movable bearing to move upward, thereby driving the movable plate of the drip assembly group to move upward until the movable plate moves to a position parallel to the top of the screw rod; the first movable member is used to connect the movable plate and the connecting arm, the second movable member is used to connect the pedestal and the connecting arm, the connecting arm is used to connect the movable plate and the pedestal, when the movable plate moves up and down, the pedestal at the other end of the movable arm is driven to move inside the shell, when the movable plate moves to a position parallel to the top of the screw rod, the pedestal just moves to a position close to a certain squeezing ball, and the dropper is used to drip out the dyeing reagent;

[0010] The metering component includes a telescopic cylinder welded to the bottom end of the lead screw. The bottom output end of the telescopic cylinder is connected to the telescopic rod. A number of fixed rings are arranged up and down on the peripheral side of the telescopic rod. Unequal numbers of extrusion balls are welded to the peripheral side of each fixed ring, and the extrusion balls are evenly distributed around the peripheral side of the fixed ring. The telescopic cylinder is used to drive the telescopic rod to expand and contract. Thus, when the pedestal just moves to a position near a certain extrusion ball, the length of the telescopic rod is adjusted to ensure that a certain fixed ring is just near the rubber sleeve. Rotating the fixed ring can squeeze the rubber sleeve through the extrusion balls.

[0011] Preferably, the XY-axis driving component includes an X-axis driving motor arranged on the base. An X-axis linear guide rail is installed on the base. The output end of the X-axis driving motor is connected to the X-axis linear guide rail. An X-axis sliding seat is slidably arranged on the X-axis linear guide rail. The top of the X-axis sliding seat is fixedly connected to the Y-axis linear guide rail. A Y-axis sliding seat is slidably arranged on the Y-axis linear guide rail. A Y-axis driving motor for driving the Y-axis sliding seat to move on the Y-axis linear guide rail is installed on the Y-axis sliding seat. A mounting frame is fixedly installed on one side surface of the Y-axis sliding seat. The bottom of the mounting frame is fixedly connected to the outer shell. A mounting arm is fixedly connected to each of the opposite side surfaces of the Y-axis sliding seat. A staining table is welded between one ends of the two mounting arms. The staining table is of a hollow structure and is used for immersing the section glass slide in the water inside the cleaning tank for cleaning.

[0012] Preferably, the switching component further includes a switching motor fixedly connected to the inner wall of the outer shell. The bottom output end of the switching motor is fixedly connected to the top end of the connecting shaft. A collar is fixedly connected to the outer side of the connecting shaft near the lead screw. Four first springs are arrayedly installed on the bottom side surface of the collar. The bottoms of the four first springs are all welded to the rebounding plate. The rebounding plate is a hollow ring structure and is arranged to move up and down on the peripheral side of the connecting shaft. The bottom of the rebounding plate rotates and rubs against the movable bearing. The collar is used for fixing on the connecting shaft, and the four first springs are used for connecting the rebounding plate and ensuring that the rebounding plate can rebound. When a certain set of liquid dropping components finishes dropping liquid, and at this time the movable bearing is still on the connecting shaft, the switching motor is reversely driven, the rebounding plate is no longer squeezed, the first springs reset and push the rebounding plate downward, and at the same time drive the movable bearing in contact with the rebounding plate to receive a downward force, so as to smoothly thread-connect with the lead screw and drive the dropper back to the original position.

[0013] Preferably, four circular grooves are arranged in an array on the peripheral side of the installation kit, and a contact sensor is installed at the bottom of each circular groove. An electromagnet is welded around each circular groove of the installation kit. Only one of the four electromagnets is energized each time it works, and the other three electromagnets are in a de-energized state. When working, the energized electromagnet is used to adsorb the telescopic rod made of the same metal material into the circular groove. After the contact sensor contacts a certain telescopic shaft, it sends a signal to the dyeing device, thereby starting the switching motor to work.

[0014] Preferably, the liquid dropping assembly further includes a fixed block welded to the top of the movable plate. The cross-section of the movable plate is fan-shaped, and the cross-sections of each movable plate of the four groups of liquid dropping assemblies enclose a complete hollow circle at the center; a mounting pipe is installed on one side of the fixed block, and an activity groove is opened inside the mounting pipe. An annular baffle is arranged on the inner wall of the notch of the activity groove. The telescopic shaft is movably arranged inside the activity groove. A third spring is sleeved on the peripheral side of a section of the telescopic shaft inside the activity groove. One end of the third spring is fixed to the inner side of the annular baffle, and the other end is fixed to the bottom of the activity groove; one end of the telescopic shaft penetrates through the annular baffle to the outside of the activity groove and is directly opposite to one of the circular grooves on the installation kit.

[0015] Preferably, one side of the rubber sleeve is connected to one end of the infusion tube, and the other end of the infusion tube penetrates through the outer shell to its outside and is connected to the liquid storage bin. The liquid storage bin is fixedly connected to the outer wall of the outer shell; the infusion tube is a rubber hollow hose for connecting the liquid storage bin and the rubber sleeve to transport the dyeing reagent inside the liquid storage bin to the inside of the rubber sleeve.

[0016] Preferably, the rubber sleeve is of a spherical structure. When the rubber sleeve is squeezed, the dyeing reagent inside it drips out from the dropper. The amount of the dyeing reagent dropped by the dropper is determined by the number of extrusion balls distributed on the peripheral side of the fixed ring. The output power and the output time each time of the switching motor are constant values.

[0017] Preferably, a connecting rod is fixedly connected to the top of the movable plate of each group of liquid dropping assemblies. The top of the connecting rod is sleeved inside the sleeve, and the top of the sleeve is welded to the inner wall of the outer shell; a second spring is sleeved on the peripheral side of the connecting rod.

[0018] The present invention has the following beneficial effects:

[0019] 1. By setting the XY-axis drive assembly, the present invention can complete all steps of the entire staining process. Place the pathological section on the surface of the staining table, and use different dropping components inside the dropping device to stain the pathological section separately. After each staining, move the pathological section into the cleaning tank through the Y-axis linear guide for cleaning. The inside of the cleaning tank can be partitioned to hold distilled water and tap water. Different staining reagents are cleaned with different cleaning liquids. During cleaning, move the pathological section horizontally through the X-axis linear guide. This process can fully automate the cleaning process of the pathological section, which is simple, rapid, and effective.

[0020] 2. By setting the switching assembly, when using a certain group of dropping components for staining drops, connect this group of dropping components to the switching assembly, start the switching motor to drive the connecting shaft and the lead screw to rotate, thereby driving the movable bearing to move upward. The mounting kit outside the movable bearing is connected to this group of dropping components, so it is also driven to move upward simultaneously until this group of dropping components move to the top position of the lead screw. At this time, still maintain the operation of the switching motor, so that the movable bearing always rotates on the outer side of the connecting shaft. At this time, the dropper of this group of dropping components is located directly above the section slide, so as to perform the dropping operation. The switching assembly can replace different dropping components to stain different positions of the section.

[0021] 3. By setting the dropping components, when a certain group of dropping components needs to be stained, start the electromagnet directly opposite the telescopic shaft of this group of dropping components. After the electromagnet is energized, it attracts the telescopic shaft to move into the circular groove inside the mounting kit until one end of the telescopic shaft contacts the contact sensor inside the circular groove. The contact sensor transmits the contact signal to the control center of the staining equipment, thereby starting the switching motor for dropping work; after the staining of this group of dropping components is completed, the dropping components return to their original positions, cut off the power supply of the electromagnet, and the telescopic shaft is affected by the reset of the third spring and leaves the inside of the circular groove and returns to the inside of the mounting tube; this structure can independently control the four groups of dropping components to perform staining operations on different parts.

[0022] 4. By setting the metering assembly, when the dropper of a certain group of dropping components moves directly above the section, according to the main function of the staining of this group of dropping components and the amount of staining agent required for staining, start the telescopic cylinder to drive different fixed rings to move up and down. If the dropping amount is large, select the fixed ring with more extrusion balls; if the dropping amount is small, select the fixed ring with fewer extrusion balls. Set the appropriate fixed ring parallel to the rubber sleeve. At this time, the switching motor is still driving the connecting shaft, the lead screw, and the metering assembly at the bottom to rotate. At this time, the rotating fixed ring drives the extrusion balls to continuously squeeze the rubber sleeve. Each time the rubber sleeve is squeezed by an extrusion ball, a drop of staining reagent will be dropped through the dropper. According to the preset dropping amount of the staining reagent, stop driving the switching motor after the dropping is completed. This structure can accurately control the dropping amount of the staining reagent, so it can improve the accuracy of section staining and reduce the waste of staining reagent. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] To more clearly illustrate the technical solutions of the embodiments of the present invention, the following will briefly introduce the drawings required for describing the embodiments. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings.

[0024] Figure 1 is a schematic diagram of the overall structure of the pathological section staining device provided by the present invention;

[0025] Figure 2 is a schematic diagram of the overall structure of the dropping device of the pathological section staining device provided by the present invention;

[0026] Figure 3 is a schematic diagram of the internal structure of the dropping device of the pathological section staining device provided by the present invention;

[0027] Figure 4 For the present invention Figure 3 is an enlarged view of part A;

[0028] Figure 5 is a schematic diagram of the sectional structure of the dropping device of the pathological section staining device provided by the present invention;

[0029] Figure 6 is a schematic diagram of the structure of the dropping component of the pathological section staining device provided by the present invention in the non-dropping state;

[0030] Figure 7 is a schematic diagram of the structure of the dropping component of the pathological section staining device provided by the present invention in the dropping state;

[0031] Figure 8 is a schematic diagram of the sectional structure of part of the switching component of the pathological section staining device provided by the present invention.

[0032] In the drawings, the list of components represented by each reference numeral is as follows:

[0033] 1. X-axis drive motor; 2. X-axis linear guide; 3. Y-axis drive motor; 4. Y-axis linear guide; 5. Cleaning tank; 6. Installation arm; 7. Dyeing table; 8. Mounting bracket; 9. Outer shell; 10. Switching motor; 11. Connecting shaft; 12. Lead screw; 13. Collar; 14. First spring; 15. Rebound plate; 16. Movable bearing; 17. Installation kit; 18. Contact sensor; 19. Electromagnet; 20. Telescopic cylinder; 21. Telescopic rod; 22. Fixed ring; 23. Extrusion ball; 24. Sleeve; 25. Connecting rod; 26. Second spring; 27. Movable plate; 28. Fixed block; 29. Installation pipe; 30. Third spring; 31. Telescopic shaft; 32. First movable part; 33. Connecting arm; 34. Second movable part; 35. Pedestal; 36. Infusion tube; 37. Rubber sleeve; 38. Dropper; 39. Liquid storage bin; 40. X-axis slide; 41. Y-axis slide. Detailed implementation manners

[0034] In order to make the technical means, creative features, achieved purposes and functions of the present invention easy to understand, the present invention will be further described below in conjunction with specific implementation manners.

[0035] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "upper", "lower", "inner", "outer", "front end", "rear end", "both ends", "one end", "the other end", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present invention. In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0036] In the description of the present invention, it should be noted that unless otherwise clearly specified and limited, the terms "installation", "provided with", "connection", etc. should be understood in a broad sense. For example, "connection" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the internal communication of two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific situations.

[0037] Refer to Figure 1-8The present invention is a pathological section staining device, comprising an XY axis driving component, and a cleaning tank 5 arranged at the bottom of the XY axis driving component, a dripping device is arranged on the XY axis driving component, the dripping device comprises a shell 9, a switching component is arranged inside the shell 9, four groups of dripping components are evenly distributed around the switching component, and different staining reagents are arranged inside the liquid storage tank 39 of each group of dripping components; a quantity control component is arranged at the bottom of the switching component, the cleaning tank 5 is used to hold distilled water for washing excess staining reagents on the section slide, the shell 9 is used to protect the internal components, and the liquid storage tank 39 is used to load the staining reagent;

[0038] The switching assembly includes a connecting shaft 11, the bottom end of which is fixedly connected to the top end of the screw rod 12, a movable bearing 16 is threadedly connected to the side surface of the screw rod 12, and an installation kit 17 is movably connected to the outer side of the movable bearing 16, and the outside of the installation kit 17 is movably connected to four groups of dripping assemblies, and each time the dripping is started, only one group of dripping assemblies is started to drip; the connecting shaft 11 is used to connect the switching motor 10 and the screw rod 12, and when the movable bearing 16 on the screw rod 12 moves to the top of the screw rod 12, the movable bearing 16 continues to move upward to the bottom of the side surface of the connecting shaft 11, and when the connecting shaft 11 continues to rotate, it will not affect the lifting and lowering of the movable bearing 16; the installation kit 17 is installed on the outer surface of the movable bearing 16, and is used to connect with the dripping assembly;

[0039] The drip assembly includes a movable plate 27, one end of a telescopic shaft 31 above the movable plate 27 is directly opposite to a circular groove provided on the outside of the installation kit 17, and the telescopic shaft 31 is movably arranged inside the circular groove, the bottom of the movable plate 27 is connected to one end of a connecting arm 33 through a first movable member 32, the other end of the connecting arm 33 is welded to the top of a pedestal 35 through a second movable member 34, a rubber sleeve 37 is fixedly connected to the bottom of the pedestal 35, a dropper 38 is connected and penetrated at the bottom end of the rubber sleeve 37, and a dripping port at the bottom end of the dropper 38 is located directly above the slice glass placed on the staining table 7, the movable plate 27 is lifted up and down driven by the switching assembly, and only one movable plate 27 is lifted up and down at a time, and when the telescopic shaft 31 of a certain group of drip assemblies is inserted into the installation kit 17, the movable plate 27 is lifted up and down, and the movable plate 27 is lifted up and down at a time, and the movable plate 27 is lifted up and down when the telescopic shaft 31 of the drip assembly is inserted into the installation kit 17. When the movable plate 27 is moved to a position parallel to the top of the screw rod 12, the screw rod 12 rotates to drive the movable bearing 16 to move upward, thereby driving the movable plate 27 of the drip assembly to move upward until the movable plate 27 moves to a position parallel to the top of the screw rod 12; the first movable member 32 is used to connect the movable plate 27 and the connecting arm 33, the second movable member 34 is used to connect the pedestal 35 and the connecting arm 33, the connecting arm 33 is used to connect the movable plate 27 and the pedestal 35, when the movable plate 27 moves up and down, the pedestal 35 at the other end of the movable arm 33 is driven to move inside the housing 9, when the movable plate 27 moves to a position parallel to the top of the screw rod 12, the pedestal 35 just moves to a position close to a certain squeezing ball 23, and the dropper 38 is used to drip out the dyeing reagent;

[0040] The metering component includes a telescopic cylinder 20 welded to the bottom end of the lead screw 12. The bottom output end of the telescopic cylinder 20 is connected to the telescopic rod 21. A number of fixing rings 22 are arranged up and down on the circumferential side of the telescopic rod 21. Unequal numbers of extrusion balls 23 are welded to the circumferential side of each fixing ring 22. The extrusion balls 23 are evenly distributed around the circumferential side of the fixing ring 22. The telescopic cylinder 20 is used to drive the telescopic rod 21 to expand and contract. Thus, when the pedestal 35 just moves to a position adjacent to a certain extrusion ball 23, the length of the telescopic rod 21 is adjusted to ensure that a certain fixing ring 22 is just near the rubber sleeve 37. Rotating the fixing ring 22 can extrude the rubber sleeve 37 through the extrusion ball 23.

[0041] Among them, the XY-axis drive component includes an X-axis drive motor 1. The X-axis drive motor 1 is arranged on the base. An X-axis linear guide rail 2 is installed on the base. The output end of the X-axis drive motor 1 is connected to the X-axis linear guide rail 2. An X-axis slide 40 is slidably arranged on the X-axis linear guide rail 2. The top of the X-axis slide 40 is fixedly connected to the Y-axis linear guide rail 4. A Y-axis slide 41 is slidably arranged on the Y-axis linear guide rail 4. A Y-axis drive motor 3 for driving the Y-axis slide 41 to move on the Y-axis linear guide rail 4 is installed on the Y-axis slide 41. A mounting bracket 8 is fixedly installed on one side surface of the Y-axis slide 41. The bottom of the mounting bracket 8 is fixedly connected to the housing 9. One mounting arm 6 is fixedly connected to each of the opposite side surfaces of the Y-axis slide 41. A staining table 7 is welded between the ends of the two mounting arms 6. The staining table 7 is a hollow structure and is used to immerse the section slide in the water inside the cleaning tank 5 for cleaning.

[0042] Among them, the switching component further includes a switching motor 10. The switching motor 10 is fixedly connected to the inner wall of the housing 9. The bottom output end of the switching motor 10 is fixedly connected to the top end of the connecting shaft 11. A collar 13 is fixedly connected to the outer side of the connecting shaft 11 near the position of the lead screw 12. Four first springs 14 are arrayedly installed on the bottom side surface of the collar 13. The bottoms of the four first springs 14 are all welded to the resilient plate 15. The resilient plate 15 is a hollow annular structure and is movably arranged up and down on the circumferential side of the connecting shaft 11. The bottom of the resilient plate 15 rotates and rubs against the movable bearing 16. The collar 13 is used to be fixed on the connecting shaft 11, and the four first springs 14 are used to connect the resilient plate 15 and ensure that the resilient plate 15 can rebound. When a certain set of liquid dropping components finishes dropping liquid, and at this time the movable bearing 16 is still on the connecting shaft 11, the switching motor 10 is driven in the reverse direction. The resilient plate 15 is no longer squeezed. The first spring 14 resets and pushes the resilient plate 15 downward, and at the same time drives the movable bearing 16 in contact with the resilient plate 15 to receive a downward force, so as to smoothly thread-connect with the lead screw 12 and drive the dropper 38 back to the original position.

[0043] Among them, four circular grooves are provided on the side surface of the installation kit 17 in a circumferential array. A contact sensor 18 is installed at the bottom of each circular groove. An electromagnet 19 is welded around each circular groove of the installation kit 17. Only one of the four electromagnets 19 is energized each time it works, and the other three electromagnets are in a de-energized state. When working, the energized electromagnet 19 is used to adsorb the metal telescopic rod 21 of the same material into the circular groove. After the contact sensor 18 contacts a certain telescopic shaft 31, it sends a signal to the dyeing device, thereby starting the switching motor 10 to work.

[0044] Among them, the drip component further includes a fixed block 28. The fixed block 28 is welded to the top of the movable plate 27. The cross-section of the movable plate 27 is fan-shaped. The cross-sections of each movable plate 27 of the four groups of drip components enclose a complete circle with a hollow center; a mounting pipe 29 is installed on one side of the fixed block 28. An activity groove is provided inside the mounting pipe 29. An annular baffle is provided on the inner wall of the notch of the activity groove. The telescopic shaft 31 is movably arranged inside the activity groove. A third spring 30 is sleeved on the circumferential side surface of a section of the telescopic shaft 31 located inside the activity groove. One end of the third spring 30 is fixed to the inner side surface of the annular baffle, and the other end is fixed to the bottom of the activity groove; one end of the telescopic shaft 31 penetrates through the annular baffle to the outside of the activity groove and is opposite to one of the circular grooves on the installation kit 17.

[0045] Among them, one side of the rubber sleeve 37 is connected to one end of the infusion tube 36. The other end of the infusion tube 36 penetrates through the outer shell 9 to its outside and is connected to the liquid storage bin 39. The liquid storage bin 39 is fixedly connected to the outer wall of the outer shell 9; the infusion tube 36 is a rubber hollow hose for connecting the liquid storage bin 39 and the rubber sleeve 37 to transport the dyeing reagent inside the liquid storage bin 39 to the inside of the rubber sleeve 37.

[0046] Among them, the rubber sleeve 37 is a spherical structure. When the rubber sleeve 37 is squeezed, the dyeing reagent inside it drips out from the dropper 38. The amount of the dyeing reagent dropped by the dropper 38 is determined by the number of extrusion balls 23 distributed on the circumferential side surface of the fixed ring 22. The output power and the output time each time of the switching motor 10 are constant values.

[0047] Among them, a connecting rod 25 is fixedly connected to the top of each movable plate 27 of each group of drip components. The top of the connecting rod 25 is sleeved inside the sleeve 24. The top of the sleeve 24 is welded to the inner wall of the outer shell 9; a second spring 26 is sleeved on the circumferential side surface of the connecting rod 25.

[0048] The working principle of the present invention is as follows: When a certain set of liquid dropping components needs to be dyed, the electromagnet directly opposite the telescopic shaft of this set of liquid dropping components is activated. After the electromagnet is powered on, it attracts the telescopic shaft to move inside the circular groove of the installation kit until one end of the telescopic shaft contacts the contact sensor inside the circular groove. The contact sensor transmits the contact signal to the control center of the dyeing equipment, thereby starting the switching motor to perform the liquid dropping operation. When the dyeing of this set of liquid dropping components is completed, the liquid dropping components return to their original positions, the electromagnet is powered off, and the telescopic shaft is affected by the reset of the third spring, leaving the inside of the circular groove and returning to the inside of the installation tube. Connect this set of liquid dropping components to the switching component, start the switching motor to drive the connecting shaft and the lead screw to rotate, thereby driving the movable bearing to move upward. The installation kit outside the movable bearing is connected to this set of liquid dropping components, so it is also driven to move upward at the same time until this set of liquid dropping components move to the top position of the lead screw. At this time, the switching motor still operates, so that the movable bearing always rotates on the outer side of the connecting shaft. At this time, the dropper of this set of liquid dropping components is directly above the sliced glass slide, thereby performing the liquid dropping operation. When the dropper of a certain set of liquid dropping components moves directly above the slice, according to the main function of the dyeing of this set of liquid dropping components and the amount of dyeing agent required for dyeing, start the telescopic cylinder to drive different fixing rings to move up and down. If the dropping amount is large, select the fixing ring with more extrusion balls; if the dropping amount is small, select the fixing ring with fewer extrusion balls. Set the appropriate fixing ring parallel to the rubber sleeve. At this time, the switching motor is still driving the connecting shaft, the lead screw, and the metering component at the bottom to rotate. At this time, the rotating fixing ring drives the extrusion balls to continuously squeeze the rubber sleeve. Each time the rubber sleeve is squeezed by an extrusion ball, a drop of dyeing reagent will be dropped through the dropper. According to the preset dropping amount of the dyeing reagent, stop driving the switching motor after the liquid dropping is completed.

[0049] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. What is described in the above embodiments and the specification only illustrates the principle of the present invention. Without departing from the spirit and scope of the present invention, the present invention will have various changes and improvements, and these changes and improvements all fall within the scope of the present invention claimed. The scope of protection claimed by the present invention is defined by the appended claims and their equivalents.

Claims

1. A pathological section staining device, comprising an XY-axis driving component and a cleaning tank (5) arranged at the bottom of the XY-axis driving component, characterized in that: The XY axis driving assembly is provided with a dripping device, the dripping device comprises a housing (9), a switching assembly is provided inside the housing (9), four groups of dripping assemblies are evenly distributed around the switching assembly, and different dyeing reagents are provided inside the liquid storage bin (39) of each group of dripping assemblies; a quantity control assembly is provided at the bottom of the switching assembly; The switching assembly comprises a connecting shaft (11), the bottom end of the connecting shaft (11) is fixedly connected to the top end of the screw rod (12), the peripheral side of the screw rod (12) is threadedly connected to a movable bearing (16), the outer side of the movable bearing (16) is movably connected to an installation kit (17), the outside of the installation kit (17) is movably connected to four groups of dripping assemblies, and each time dripping, only one group of dripping assemblies is activated to drip; The liquid dripping assembly comprises a movable plate (27), one end of a telescopic shaft (31) above the movable plate (27) faces a circular groove provided on the outside of the mounting kit (17), and the telescopic shaft (31) is movably arranged inside the circular groove, the bottom of the movable plate (27) is connected to one end of a connecting arm (33) via a first movable member (32), the other end of the connecting arm (33) is welded to the top of a pedestal (35) via a second movable member (34), a rubber sleeve (37) is fixedly connected to the bottom of the pedestal (35), a dropper (38) is connected and penetrated at the bottom end of the rubber sleeve (37), and a liquid dripping port at the bottom end of the dropper (38) is located directly above a slice glass placed on the staining table (7); The control assembly comprises a telescopic cylinder (20) welded to the bottom end of a screw rod (12); the bottom output end of the telescopic cylinder (20) is connected to a telescopic rod (21); a plurality of fixing rings (22) are arranged on the upper and lower sides of the periphery of the telescopic rod (21); a different number of squeezing balls (23) are welded on the periphery of each fixing ring (22); and the squeezing balls (23) are evenly distributed around the periphery of the fixing ring (22).

2. The pathological section staining device according to claim 1, characterized in that, The XY axis drive assembly comprises an X axis drive motor (1), the X axis drive motor (1) is arranged on a base, an X axis linear guide rail (2) is installed on the base, the output end of the X axis drive motor (1) is connected to the X axis linear guide rail (2), an X axis slide seat (40) is slidably arranged on the X axis linear guide rail (2), the top of the X axis slide seat (40) is fixedly connected to the Y axis linear guide rail (4), a Y axis slide seat (41) is slidably arranged on the Y axis linear guide rail (4), and a Y axis slide seat (41) is installed on the Y axis slide seat (41). A Y-axis driving motor (3) is provided for driving a Y-axis slide (41) to move on a Y-axis linear guide rail (4); a mounting frame (8) is fixedly installed on one side of the Y-axis slide (41); the bottom of the mounting frame (8) is fixedly connected to a housing (9); two opposite side surfaces of the Y-axis slide (41) are respectively fixedly connected with a mounting arm (6); a staining table (7) is welded between one end of the two mounting arms (6); the staining table (7) is a hollow structure and is used for immersing in water inside a cleaning tank (5) to clean slice slides.

3. The pathological section staining device according to claim 2, wherein The switching assembly further comprises a switching motor (10), wherein the switching motor (10) is fixedly connected to the inner wall of the housing (9), the bottom output end of the switching motor (10) is fixedly connected to the top end of the connecting shaft (11), the outer side of the connecting shaft (11) is fixedly connected to a collar (13) near the screw rod (12), and four first springs (14) are installed in an array on the bottom side of the collar (13), and the bottoms of the four first springs (14) are welded to a rebound plate (15), the rebound plate (15) is a hollow annular structure, and the rebound plate (15) is movably arranged on the peripheral side of the connecting shaft (11) in an up-and-down manner; the bottom of the rebound plate (15) and the movable bearing (16) rotate and rub against each other.

4. A pathological section staining device according to claim 3, characterized in that, The installation kit (17) is provided with four circular grooves in an array on the side surface thereof, and a contact sensor (18) is installed at the bottom of each circular groove. An electromagnet (19) is welded around each circular groove of the installation kit (17). Only one of the four electromagnets (19) is powered on each time it is working, and the other three electromagnets are in a power-off state. When working, the electromagnet (19) that is powered on is used to adsorb the telescopic rod (17) made of the same metal material into the inside of the circular groove.

5. A pathological section staining device according to claim 4, characterized in that, The drip assembly also includes a fixed block (28), the fixed block (28) is welded on the top of the movable plate (27), the cross section of the movable plate (27) is fan-shaped, and the cross section of each movable plate (27) of the four groups of drip assemblies is surrounded by a complete circle with a hollow center; a mounting tube (29) is installed on one side of the fixed block (28), a movable groove is opened inside the mounting tube (29), a circular ring-shaped baffle is arranged on the inner wall of the groove of the movable groove, the telescopic shaft (31) is movably arranged inside the movable groove, and a third spring (30) is sleeved on the circumferential side surface of a section of the telescopic shaft (31) located inside the movable groove, one end of the third spring (30) is fixed to the inner side surface of the annular baffle, and the other end is fixed to the bottom of the movable groove; one end of the telescopic shaft (31) passes through the annular baffle to the outside of the movable groove and faces one of the circular grooves on the mounting kit (17).

6. A pathological section staining device according to claim 5, wherein, One side of the rubber sleeve (37) is connected to one end of the infusion tube (36), and the other end of the infusion tube (36) passes through the outer shell (9) to the outside thereof and is connected to the liquid storage bin (39), and the liquid storage bin (39) is fixedly connected to the outer wall of the outer shell (9); the infusion tube (36) is a hollow hose made of rubber material, which is used to connect the liquid storage bin (39) and the rubber sleeve (37) to transport the dyeing reagent inside the liquid storage bin (39) to the inside of the rubber sleeve (37).

7. The pathological section staining device according to claim 6, characterized in that, The rubber sleeve (37) is a spherical structure. When the rubber sleeve (37) is squeezed, the dyeing reagent inside it drips out from the dropper (38). The amount of dyeing reagent dripped out of the dropper (38) is determined by the number of squeezing balls (23) distributed on the side surface of the fixed ring (22). The output power of the switching motor (10) and the output time of each time are constant values.

8. A pathological section staining device according to claim 7, wherein, At the top of the movable plate (27) of each drip component, a connecting rod (25) is fixedly connected. The top of the connecting rod (25) is sleeved inside a sleeve (24), and the top of the sleeve (24) is welded to the inner wall of the housing (9); a second spring (26) is sleeved on the circumferential side of the connecting rod (25).

Images