Signal acquisition and stimulation device for spinal cord bridging repair and method thereof

Abstract

The invention discloses a signal acquisition and stimulation device for spinal cord bridging repair and a method thereof. The device is respectively connected with two ends of a spinal cord injury part in a bridging manner, and bioelectrical signals of the two ends are acquired and stimulated; the device comprises a main control board used for collecting and processing bio-electricity signals and communicating and sending control signals and an electrical stimulation board used for outputting specific waveforms, the two boards are provided with connecting ports connected with implanted and percutaneous electrode assemblies, and the device can be suitable for injuries of different areas by being connected with the electrode assemblies of different sizes. According to the miniature circuit device, a biological electric signal can be collected through an implantable element according to a spinal cord injury position, and signal conduction between nerves of upper and lower injured parts can be recovered through implantation or percutaneous contact and bypassing of the spinal cord injury part, so that the injured nervous system can be repaired; the device has the characteristics of miniaturization and generalization, and avoids the inconvenience of movement and transmission of a brain-computer interface and limb rehabilitation equipment.

Description

Technical Field

[0001] The present invention relates to a signal acquisition and stimulation device, and to the technical field of bioelectric signal conduction and stimulation, and in particular to a signal acquisition and stimulation device and a method thereof that can be used for spinal cord bridging repair. Background Art

[0002] In recent years, spinal cord bridging technology, as an emerging neurorepair method, has provided new hope for the functional reconstruction of patients with spinal cord injury (SCI). This technology bypasses the injured part of the spinal cord through implanted electronic devices or biomaterials, restores the signal conduction between the nerves above and below the injury, and thus achieves partial recovery of motor and sensory functions. Combining neural interface devices with advanced signal processing technology, spinal cord bridging technology is expected to bring more effective treatment options for SCI patients and become an important development direction in the field of neurorepair.

[0003] With the continuous development of science and technology, the collection and processing of micro-electric signals are becoming more and more perfect. The brain-computer interface-neuromotor system has also become the most intuitive rehabilitation treatment mode. By receiving and analyzing the activity pattern of the patient's brain, the intention is converted into actual movement instructions and simulated neural signals, which are transmitted to the muscles or spinal cord through the stimulation device to promote the regeneration or functional replacement of neural pathways, as well as various medium and large medical rehabilitation equipment, which drive limb movement through mechanical structure and motor transmission to seek long-term rehabilitation. However, there are certain limitations, and there are also the following problems: 1. The signals contained in the brain-computer interface solution are complex, and there are many signals that are not related to behavioral instructions, which leads to the impurity of the signal, making the signal processing task too large, which is not conducive to the transmission of the signal. 2. When the brain-computer interface is facing the spinal cord repair function, the position of the signal receiving end is fixed, and the position of the spinal cord injury as the stimulation end is uncertain. Therefore, the signal transmission distance of the device will be unfixed, facing the problems of long span and large volume, which is easy to bring and remove many inconveniences in life to patients. 3. The current mainstream spinal cord injury rehabilitation equipment is usually large in size and is mainly used for the lower limbs or fixed spinal cord damaged areas. It has the disadvantages of fixed use location and inconvenience in carrying. Summary of the invention

[0004] In order to solve the problems existing in the background technology, the present invention provides a signal collection and stimulation device and method that can be used for spinal cord bridging repair. The present invention can use spinal cord bridging to output bioelectric stimulation to achieve spinal cord nerve repair.

[0005] The technical solution adopted by the present invention is:

[0006] 1. A signal acquisition and stimulation device for spinal cord bridging repair, comprising:

[0007] An electrode assembly and a circuit module. The electrode assembly contacts the spinal cord injury of the human body and is used for collecting and transmitting the bioelectric signals of the human body and transmitting the output electrical stimulation signals of the circuit module. The electrode assembly includes a first spinal dura mater electrode, an electrode patch, and a second spinal dura mater electrode. The first spinal dura mater electrode is used for implantable collection of the bioelectric signals of the human body. The electrode patch is used for percutaneous electrical signal stimulation of the spinal cord injury of the human body. The second spinal dura mater electrode is used for implantable electrical signal stimulation of the spinal cord injury of the human body.

[0008] The circuit module includes a main control board and an electrical stimulation board. The bioelectric signals of the human body collected are received through the first spinal dura mater electrode, and the signals for electrical stimulation are transmitted sequentially through the main control board and the electrical stimulation board, and electrical stimulation of the spinal cord injury of the human body is performed through the second spinal dura mater electrode or the electrode patch.

[0009] The first spinal dura mater electrode and the second spinal dura mater electrode are implanted into the interior of the spinal cord injury of the human body through minimally invasive surgery and are respectively located at both ends of the spinal cord injury in contact with the human body; the electrode patch is attached to the epidermis of the spinal cord injury of the human body.

[0010] The signal acquisition and stimulation device further includes a housing and a plurality of nylon columns. The main control board and the electrical stimulation board have the same size. The main control board and the electrical stimulation board are horizontally arranged at intervals from bottom to top inside the housing and are connected and fixed through the respective nylon columns at their positioning holes. The four corners of the main control board are respectively provided with first positioning holes, the four corners of the electrical stimulation board are respectively provided with second positioning holes, and the four corners of the inner bottom surface of the housing are respectively provided with third positioning holes. The first positioning holes, the second positioning holes, and the third positioning holes with the central axes on the same vertical line are respectively connected and fixed by two nylon columns up and down, and the housing and the bottom of the nylon column are fixed by using countersunk bolts at the third positioning holes.

[0011] The described main control board includes a microcontroller unit (MCU) chip, an analog-to-digital converter (ADC) chip, a digital-to-analog converter (DAC) chip, a first flexible printed circuit (FPC) connector, a Bluetooth WIFI module, and a first IPEX interface. The first IPEX interface is located at the edge of the main control board. The first FPC connector is electrically connected to the ADC chip. Both the ADC chip and the DAC chip communicate with the MCU chip through a serial peripheral interface (SPI). The first FPC connector is electrically connected to the first spinal dura electrode. The first FPC connector serves as a receiving end for transmitting and receiving electrical signals, ensuring that the main control board has a small size while enabling multi-channel acquisition and stimulation. The DAC chip, as the first voltage output terminal, is electrically connected to the electrical stimulation board through the first IPEX interface. The MCU chip performs wireless transmission with an external remote terminal through Bluetooth WIFI.

[0012] The described main control board further includes a charging circuit and a Type-C interface. The Type-C interface is located at the edge of the main control board. The charging circuit charges an external battery through the Type-C interface and is electrically connected to the MCU chip for power supply. The MCU chip communicates with an external host computer through the Type-C interface for serial communication.

[0013] The described electrical stimulation board includes a BOOST boost circuit, a multi-channel operational amplifier, a second FPC connector, a connector socket, and a second IPEX interface. The BOOST boost circuit is electrically connected to the multi-channel operational amplifier. The DAC chip of the main control board is electrically connected to the multi-channel operational amplifier through the first IPEX interface and the second IPEX interface in sequence. The multi-channel operational amplifier is electrically connected to the second spinal dura electrode through the second FPC connector and is electrically connected to the electrode patch through the connector socket.

[0014] II. An electrical stimulation method for a signal acquisition and stimulation device that can be used for spinal bridging repair:

[0015] When the described signal acquisition and stimulation device performs electrical stimulation on the spinal cord injury of the human body, first, weak bioelectric signals are collected through the first spinal dura electrode and the analog-to-digital conversion ADC chip, and then transmitted to the control unit MCU chip. The control unit MCU chip transmits the signals received from multiple channels to the external host computer through the transmission protocol for real-time display and storage of data. At the same time, the micro-control unit MCU chip performs wireless transmission of signals with the external remote end through the Bluetooth WIFI module; the external host computer sends electrical stimulation instructions to the micro-control unit MCU chip of the main control board, thereby sending a pulse modulation waveform signal to the digital-to-analog conversion DAC chip for digital-to-analog conversion, and then sequentially transmitting it to the multi-channel operational amplifier through the first IPEX interface and the second IPEX interface. The overall voltage signal of the boosted electrical stimulation board is transmitted to the multi-channel operational amplifier through the BOOST boost circuit, and the multi-channel operational amplifier outputs voltage signals respectively through the second flexible printed circuit FPC connector and the connector socket to perform current stimulation on the spinal cord injury of the human body in an implanted or percutaneous manner, realizing spinal cord bridging and repair.

[0016] The beneficial effects of the present invention are:

[0017] The present invention designs a miniaturized bioelectric signal acquisition and electrical stimulation module, adopts the spinal cord bridging technology, and realizes the nerve repair of spinal cord injury. According to the position of spinal cord injury, through implanted or percutaneous contact, it bypasses the spinal cord injury site, restores the signal conduction between the nerves in the upper and lower parts of the injury, and realizes the repair of the damaged nervous system. The device has the characteristics of miniaturization and generalization, avoiding the inconvenience of brain-computer interfaces and limb rehabilitation equipment in terms of movement and transmission. Description of the Drawings

[0018] Figure 1 Schematic diagram of the artificial bridge connection between the spinal cords;

[0019] Figure 2 Schematic diagram of the electrical stimulation device of the present invention;

[0020] Figure 3 Schematic diagram of the main control board and the electrical stimulation board of the present invention;

[0021] Figure 4 Schematic diagram of setting the repair electrical stimulation mode for the micro-control unit MCU chip of the present invention;

[0022] Figure 5 Structural diagram of the electrical stimulation device of the present invention;

[0023] In the figure: 1. Main control board, 1-1. Micro control unit MCU chip, 1-2. Analog-to-digital conversion ADC chip, 1-3. Digital-to-analog conversion DAC chip, 1-4. First flexible printed circuit FPC connector, 1-5. Bluetooth WIFI module, 1-6. First IPEX interface, 1-7. First spinal dura electrode, 2. Electrical stimulation board, 2-1. BOOST boost circuit, 2-2. Multichannel operational amplifier, 2-3. Second flexible printed circuit FPC connector, 2-4. Connector socket, 2-5. Electrode patch, 2-6. Second IPEX interface, 2-7. Second spinal dura electrode, 3. Housing, 3-1. Nylon column, 3-2. Third positioning hole, 3-3. First notch, 3-4. Second notch. Detailed implementation mode

[0024] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0025] As Figure 1 shown, for the specific spinal cord injury positioning of the present invention, first, an artificial bridge connection between the spinal cords needs to be established, the collection is carried out through an implantable method, and the stimulation is carried out through a percutaneous or implantable method, and the ascending signal is transmitted to the descending execution nerve. The bioelectrical signals at the upper end of the spinal cord injury are collected, and the collected bioelectrical signals can be analyzed subsequently through machine learning, and appropriate current stimulation or voltage stimulation is output at the lower end of the spinal cord injury to assist the normal transmission of nerve signals.

[0026] As Figure 2 and Figure 3As shown in the figure, the signal acquisition and stimulation device for spinal cord bridging repair of the present invention includes an electrode assembly and a circuit module. The electrode assembly is in contact with the spinal cord injury of the human body and is used for the acquisition and transmission of bioelectric signals of the human body and the transmission of the output electric stimulation signals of the circuit module. The electrode assembly includes a first spinal dura mater electrode 1-7, an electrode patch 2-5, and a second spinal dura mater electrode 2-7. The first spinal dura mater electrode 1-7 is used for implantable acquisition of bioelectric signals of the human body. The electrode patch 2-5 is used for percutaneous electrical signal stimulation of the spinal cord injury of the human body. The second spinal dura mater electrode 2-7 is used for implantable electrical signal stimulation of the spinal cord injury of the human body. The circuit module includes a main control board 1 with a size of 30mm * 50mm and an electrical stimulation board 2. The main control board 1 has multi-channel acquisition and multi-channel stimulation control functions. Facing the situation of multi-point spinal cord injury and multi-point electrical stimulation requirements, the main function of the main control board 1 is that the analog-to-digital conversion ADC receives the bioelectric signals transmitted by the electrode assembly and transmits them to the microcontroller unit MCU1-1. The microcontroller unit MCU1-1 analyzes and processes the transmitted data and controls the digital-to-analog conversion DAC voltage output. At the same time, it communicates with the microcontroller unit MCU1-1 through an external host computer or remote terminal to set the function parameters of the analog-to-digital conversion ADC and the digital-to-analog conversion DAC. The device receives the bioelectric signals of the human body collected by the first spinal dura mater electrode 1-7, transmits the signals for electrical stimulation sequentially through the main control board 1 and the electrical stimulation board 2, and performs electrical stimulation on the spinal cord injury of the human body through the second spinal dura mater electrode 2-7 or the electrode patch 2-5, and can respectively realize implantable and percutaneous bioelectric signal acquisition and electrical stimulation functions according to requirements.

[0027] The main control board 1 of the present invention includes a microcontroller unit MCU chip 1-1, an analog-to-digital conversion ADC chip 1-2, a digital-to-analog conversion DAC chip 1-3, a first flexible printed circuit FPC connector 1-4, a Bluetooth WIFI module 1-5, and a first IPEX interface 1-6. The first IPEX interface 1-6 is located at the edge of the main control board 1, and the first flexible printed circuit FPC connector 1-4 has 20 pins. The first flexible printed circuit FPC connector 1-4 is electrically connected to the analog-to-digital conversion ADC chip 1-2. Both the analog-to-digital conversion ADC chip 1-2 and the digital-to-analog conversion DAC chip 1-3 communicate with the microcontroller unit MCU chip 1-1 through the serial peripheral interface SPI. The first flexible printed circuit FPC connector 1-4 is electrically connected to the first spinal dura mater electrode 1-7. The first flexible printed circuit FPC connector 1-4 serves as a receiving end for electrical signal transceiver. It ensures that the main control board 1 still has a small size while being able to achieve multi-channel acquisition and stimulation. The digital-to-analog conversion DAC chip 1-3 is electrically connected to the electrical stimulation board 2 through the first IPEX interface 1-6 as the first voltage output end. The microcontroller unit MCU chip 1-1 performs wireless transmission with an external remote terminal through Bluetooth WIFI1-5, and Bluetooth WIFI1-5 uses ESP32.

[0028] In the human-computer interaction of the present invention, the microcontroller unit (MCU) chip 1-1 has a built-in and complete input-output parameter setting function, and the output and acquisition channels are independently controlled. Serial communication with the host computer is achieved through the Type-C interface 1-8. By transmitting instructions to the microcontroller unit (MCU) chip 1-1, the reset of the analog-to-digital conversion (ADC) chip 1-2 and the digital-to-analog conversion (DAC) chip 1-3 is realized. At the acquisition end, the differential and single-ended functions can be switched, and the sampling rate, sampling range, and number of sampling channels can be changed. Different settings have different sampling errors, and the lowest can be less than 10 μV, which is applicable to the R & D experimental stage of different organisms. Compared with the existing fixed-mode transcutaneous electrical stimulation mode at the output end, this module can set the output voltage value of each channel by itself, or store specific output waveforms on the host computer, accurate to the 0.1 mV level. This module defaults to enabling the four-channel differential and 300 Hz * 4 rate acquisition mode. Channel 0 outputs mode A (i.e., 30 Hz is paired with 10 kHz), and channels 1 to 15 output 0 V.

[0029] The main control board 1 of the present invention also includes a Bluetooth WIFI module 1-5 for signal transmission with the control unit MCU chip 1-1, and wirelessly connects to mobile phones and other external remote terminals. The Bluetooth WIFI module 1-5 supports 2.4 GHz Wi-Fi 6, Bluetooth 5, and Zigbee 3.0, and can realize the wireless communication and wireless control functions of this device. Compared with the common single fixed-mode switching electrical stimulation function, the combination of the multi-channel bioelectric signal acquisition and multi-channel electrical stimulation functions of the present invention with the wireless transmission function can provide physical technical support for remote consultation and AI diagnosis, and at the same time help reduce the labor cost of medical rehabilitation and achieve portable treatment.

[0030] The main control board 1 of the present invention further includes a charging circuit and a Type-C interface. The Type-C interface is located at the edge of the main control board 1. The charging circuit charges the external battery through the Type-C interface, and the charging circuit is electrically connected to the microcontroller unit (MCU) chip 1-1 for power supply. The microcontroller unit (MCU) chip 1-1 conducts serial communication with the external host computer through the Type-C interface.

[0031] The electric stimulation board 2 of the present invention includes a BOOST boost circuit 2-1, a multi-channel operational amplifier 2-2, a second flexible printed circuit FPC connector 2-3, a connector socket 2-4, and a second IPEX interface 2-6. The BOOST boost circuit 2-1 is electrically connected to the multi-channel operational amplifier 2-2. The digital-to-analog conversion DAC chip 1-3 of the main control board 1 is electrically connected to the multi-channel operational amplifier 2-2 through the first IPEX interface 1-6 and the second IPEX interface 2-6 in sequence. The multi-channel operational amplifier 2-2 is electrically connected to the second spinal dural electrode 2-7 through the second flexible printed circuit FPC connector 2-3. The multi-channel operational amplifier 2-2 is electrically connected to the electrode patch 2-5 through the connector socket 2-4.

[0032] This device is not only applicable to implantable voltage stimulation but also to transcutaneous electrical stimulation and current stimulation. The common practice of transcutaneous stimulation devices is to default the human skin resistance to 1000Ω, and then the boost circuit directly performs transcutaneous stimulation. In this way, due to the non-fixed resistance during use, the current output at different positions or different times under the same control signal will be different. The size of the additional electric stimulation board 2 of the present invention is the same as that of the main control board 1. It can be laminated with the main control board 1 through the nylon column 3-1 in the positioning hole 2-3 and placed together at the housing 3. The second IPEX interface 2-6 is connected to the first IPEX interface 1-6 to transmit the DA voltage outputs of channels 0 and 1 of the digital-to-analog conversion DAC chip 1-3.

[0033] The implantable spinal dural electrodes 1-7 and 2-7 are selected for the electrical signal transmission of the present invention, which have the ability to collect and stimulate signals and are applicable to spinal cord electrical stimulation therapy. The electrode ends are made of degradable materials to avoid the risk of secondary surgery for removal. The first spinal dural electrode 1-7 and the second spinal dural electrode 2-7 are implanted into the interior of the spinal cord injury of the human body through minimally invasive surgery and are respectively located at both ends of the spinal cord injury in contact with the human body; the electrode patch 2-5 is attached to the epidermis of the spinal cord injury of the human body. The spinal dural electrodes 1-7 and 2-7 specifically adopt the spinal dural electrodes in patents CN117815540A and CN221867114U, and implantable spinal dural electrodes 1-7 and 2-7 of different sizes can be selected based on different injuries.

[0034] Such as Figure 4As shown, the electrical stimulation of the present invention uses a pulse modulation waveform. The modulated waveform is usually such that it includes a fundamental wave with a lower frequency, on which a carrier wave with a higher frequency is superimposed; the low frequency can precisely control the activation pattern of neurons and helps activate specific neuron groups. The high-frequency carrier wave can provide high-frequency pulses to ensure the continuity and stability of the signal. The present invention sets the repair electrical stimulation mode through the interrupt of the square waves output by two timers of the microcontroller unit MCU chip 1-1. The high and low frequencies of the output fixed level can be changed through an external computer connected via the Type-C interface. The present invention defaults to a low frequency of 50 Hz in combination with a high frequency of 5 kHz, the output square wave level is 0.1 v to 0.3 v, and the output fixed level is 0.2 v.

[0035] As Figure 5 shown, the signal acquisition and stimulation device of the present invention further includes a housing 3 and several nylon columns 3-1. The main control board 1 and the electrical stimulation board 2 have the same size. The main control board 1 and the electrical stimulation board 2 are horizontally arranged at intervals from bottom to top inside the housing 3 and are connected and fixed through each nylon column 3-1 at their respective positioning holes. First positioning holes are respectively opened at the four corners of the main control board 1, second positioning holes are respectively opened at the four corners of the electrical stimulation board 2, and third positioning holes 3-2 are respectively opened at the four corners of the inner bottom surface of the housing 3. The first positioning hole, the second positioning hole, and the third positioning hole 3-2 whose central axes are on the same vertical line are respectively connected and fixed by two upper and lower nylon columns 3-1, and a countersunk head bolt is used at the third positioning hole 3-2 to fix the bottom of the housing 3 and the nylon column 3-1.

[0036] The nylon column 3-1, as a non-metallic material, will not interfere with electromagnetic signals like a metal copper column, thus ensuring the transmission quality of wireless signals. Specifically, the dielectric constant of the nylon column 3-1 is about 3.0 to 3.5, which is much lower than that of the copper column, about 1.0, thereby avoiding signal attenuation and interference. At the same time, the nylon column 3-1 is used to fix two printed circuit boards PCB (Printed Circuit Board) and the housing 3. The Type-C interface 1-8 is externally connected through a notch opened on the side of the housing 3, which is used for setting the control of the electrical stimulation mode and battery charging; the housing 3 is also provided with a first notch 3-3 and a second notch 3-4. The first notch 3-3 is used for the lead wire to be connected to the electrical stimulation board 2, so as to be connected to the percutaneous electrode patch 2-5; the second notch 3-4 is used for the implantable first spinal dura electrode 1-7 to be connected to the main control board 1 and can also be used for other flexible flat cables to be connected.

[0037] The electrical stimulation method of the signal acquisition and stimulation device for spinal bridging repair of the present invention is specifically as follows:

[0038] When the signal acquisition and stimulation device performs electrical stimulation on the spinal cord injury of the human body, first, weak bioelectric signals are collected through the first spinal dura electrode 1-7 and the analog-to-digital conversion ADC chip 1-2, and then transmitted to the control unit MCU chip 1-1. The control unit MCU chip 1-1 transmits the signals received from multiple channels to the external host computer or the receiving end through the transmission protocol for real-time display and storage of data after verification. It can be displayed through the storage software JCOM, specifically using the "frame header + frame ID + number of channels + data of channel 1 +... + data of channel n + frame tail" mode. At the same time, the microcontroller unit MCU chip 1-1 performs wireless transmission of signals with the external remote end through the Bluetooth WIFI module 1-5; the external host computer sends an electrical stimulation instruction to the microcontroller unit MCU chip 1-1 of the main control board 1, thereby sending a pulse modulation waveform signal to the digital-to-analog conversion DAC chip 1-3 for digital-to-analog conversion, and setting parameters such as the acquisition mode, acquisition channels, and acquisition rate; then it is transmitted to the multi-channel operational amplifier 2-2 through the first IPEX interface 1-6 and the second IPEX interface 2-6 in sequence. The overall voltage signal of the stimulated electrode plate 2 after boosting is transmitted to the multi-channel operational amplifier 2-2 through the BOOST boost circuit 2-1. The multi-channel operational amplifier 2-2 outputs voltage signals through the second flexible printed circuit FPC connector 2-3 and the connector socket 2-4 respectively to perform current stimulation on the spinal cord injury of the human body in an implanted or percutaneous manner, realizing spinal cord bridging and repair.

[0039] The present invention defaults to setting 0.1v to 0.3v corresponding to an output of 10mA to 30mA. And it is connected to the lead wire and the percutaneous electrode patch 2-5 through the 3.5mm connector socket 2-4, and the stimulation signal is output through the implanted second spinal dura electrode 2-7 connected to the second flexible printed circuit FPC connector 2-3.

[0040] Although the preferred embodiments of the present application have been described, those skilled in the art can make additional changes and modifications to these embodiments once they know the basic creative concept. Therefore, the present invention is intended to be interpreted as including the preferred embodiments and all changes and modifications falling within the scope of the present application.

[0041] Obviously, those skilled in the art can make various changes and modifications to the present application without departing from the spirit and scope of the present application. Thus, if these modifications and variations of the present application fall within the scope of the equivalent technology of the present invention, the present application also intends to include these changes and modifications.

Claims

1. A signal acquisition and stimulation device that can be used for spinal cord bridging repair, characterized in that, Comprising: An electrode assembly and a circuit module. The electrode assembly contacts the spinal cord injury site of the human body and is used for collecting and transmitting the bioelectric signals of the human body and transmitting the electrical stimulation signals output by the circuit module. The electrode assembly includes a first spinal dura electrode (1-7), an electrode patch (2-5), and a second spinal dura electrode (2-7). The first spinal dura electrode (1-7) is used for implantably collecting the bioelectric signals of the human body. The electrode patch (2-5) is used for transcutaneously electrically stimulating the spinal cord injury site of the human body. The second spinal dura electrode (2-7) is used for implantably electrically stimulating the spinal cord injury site of the human body; The circuit module includes a main control board (1) and an electrical stimulation board (2). It receives the collected bioelectric signals of the human body through the first spinal dura electrode (1-7), sequentially transmits the signals for electrical stimulation through the main control board (1) and the electrical stimulation board (2), and performs electrical stimulation on the spinal cord injury site of the human body through the second spinal dura electrode (2-7) or the electrode patch (2-5).

2. The signal acquisition and stimulation device for spinal cord bridging repair according to claim 1, characterized in that: The first spinal dura electrode (1-7) and the second spinal dura electrode (2-7) are implanted inside the spinal cord injury site of the human body and are respectively located at both ends of the spinal cord injury site in contact with the human body; The electrode patch (2-5) is attached to the epidermis of the spinal cord injury site of the human body.

3. The signal acquisition and stimulation device for spinal cord bridging repair according to claim 1, characterized in that: The signal collection and stimulation device further includes a housing (3) and several nylon columns (3-1). The main control board (1) and the electrical stimulation board (2) have the same size. The main control board (1) and the electrical stimulation board (2) are horizontally arranged at intervals from bottom to top inside the housing (3) and are connected and fixed through the respective nylon columns (3-1) at their positioning holes.

4. The signal acquisition and stimulation device for spinal cord bridging repair according to claim 1, characterized in that: The main control board (1) includes a microcontroller unit MCU chip (1-1), an analog-to-digital conversion ADC chip (1-2), a digital-to-analog conversion DAC chip (1-3), a first flexible printed circuit FPC connector (1-4), a Bluetooth WIFI module (1-5), and a first IPEX interface (1-6). The first IPEX interface (1-6) is located at the edge of the main control board (1); The first flexible printed circuit FPC connector (1-4) is electrically connected to the analog-to-digital conversion ADC chip (1-2). Both the analog-to-digital conversion ADC chip (1-2) and the digital-to-analog conversion DAC chip (1-3) communicate with the microcontroller unit MCU chip (1-1) through the serial peripheral interface SPI. The first flexible printed circuit FPC connector (1-4) is electrically connected to the first spinal dura electrode (1-7), and the first flexible printed circuit FPC connector (1-4) serves as the receiving end; The digital-to-analog conversion DAC chip (1-3) serves as the first voltage output end and is electrically connected to the electrical stimulation board (2) through the first IPEX interface (1-6). The microcontroller unit MCU chip (1-1) performs wireless transmission with an external remote end through Bluetooth WIFI (1-5).

5. The signal acquisition and stimulation device for spinal cord bridging repair according to claim 4, characterized in that: The main control board (1) further includes a charging circuit and a Type-C interface. The Type-C interface is located at the edge of the main control board (1). The charging circuit charges an external battery through the Type-C interface. The charging circuit is electrically connected to the microcontroller unit MCU chip (1-1), and the microcontroller unit MCU chip (1-1) communicates with an external host computer through the Type-C interface for serial communication.

6. The signal acquisition and stimulation device for spinal cord bridging repair according to claim 4, characterized in that: The electric stimulation board (2) includes a BOOST boost circuit (2-1), a multi-channel operational amplifier (2-2), a second flexible printed circuit FPC connector (2-3), a connector socket (2-4), and a second IPEX interface (2-6). The BOOST boost circuit (2-1) is electrically connected to the multi-channel operational amplifier (2-2). The digital-to-analog conversion DAC chip (1-3) of the main control board (1) is electrically connected to the multi-channel operational amplifier (2-2) through the first IPEX interface (1-6) and the second IPEX interface (2-6) in sequence. The multi-channel operational amplifier (2-2) is electrically connected to the second spinal dura electrode (2-7) through the second flexible printed circuit FPC connector (2-3), and the multi-channel operational amplifier (2-2) is electrically connected to the electrode patch (2-5) through the connector socket (2-4).

7. The electrical stimulation method of the signal acquisition and stimulation device for spinal cord bridging repair according to any one of claims 1-6, characterized in that Including: When the signal acquisition and stimulation device performs electrical stimulation on the spinal cord injury of the human body, it first acquires bioelectrical signals through the first spinal dura electrode (1-7) and the analog-to-digital conversion ADC chip (1-2), and then transmits them to the control unit MCU chip (1-1). The control unit MCU chip (1-1) transmits the signals received through multiple channels to an external host computer for real-time display and storage of data through a transmission protocol. At the same time, the microcontroller unit MCU chip (1-1) performs wireless transmission of signals with an external remote end through the Bluetooth WIFI module (1-5); an external host computer sends an electrical stimulation instruction to the microcontroller unit MCU chip (1-1) of the main control board (1), thereby generating a pulse modulation waveform signal to the digital-to-analog conversion DAC chip (1-3) for digital-to-analog conversion, and then transmitting it to the multi-channel operational amplifier (2-2) through the first IPEX interface (1-6) and the second IPEX interface (2-6) in sequence. The overall voltage signal of the boosted electric stimulation board (2) is transmitted to the multi-channel operational amplifier (2-2) through the BOOST boost circuit (2-1). The multi-channel operational amplifier (2-2) outputs voltage signals through the second flexible printed circuit FPC connector (2-3) and the connector socket (2-4) to perform current stimulation on the spinal cord injury of the human body in an implanted or percutaneous manner.

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