An fnirs system and method of commissioning compatible with an mri imaging system with optimized beam length

Abstract

The application provides an fnirs system compatible with an MRI imaging system and having an optimized beam length and a debugging method. The fnirs system comprises a head cap, a set of SD probe groups on the head cap, and a host computer, the host computer specifically comprising a set of APD devices, a main processor and a processing circuit, each APD device being configured to be connected to a D probe via a first optical fiber bundle, and the D probe being kept connected with the first optical fiber bundle; the main processor and the processing circuit being configured to be electrically connected to the set of APD devices; the S probe being kept connected with a second optical fiber bundle or a second electric wire bundle to be connected to the host computer via the second optical fiber bundle or the second electric wire bundle, the length of the first optical fiber bundle being below 3 meters, and the length of the second optical fiber bundle or the second electric wire bundle also being below 3 meters. In this way, the head cap can be connected with the optical fiber bundle or the electric wire bundle below 3 meters, so as to avoid the problems of light attenuation, easy breakage during movement and inconvenience in carrying due to the overlength of the optical fiber bundle or the electric wire bundle.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of near-infrared brain function imaging, in particular to an fnirs system compatible with an MRI imaging system and having an optimized line bundle length and a debugging method. BACKGROUND

[0002] By combining magnetic resonance imaging (MRI) and near-infrared brain function imaging (fnirs) for multi-modal detection of the brain, more comprehensive brain activity information can be obtained. By combining MRI, fnirs can improve spatial resolution. fnirs can measure the time-varying concentration of cerebral oxygen, which indirectly reflects the activation degree of the cerebral cortex, which can make up for the time resolution of MRI. In summary, the combination of MRI and fnirs can more accurately diagnose and evaluate the brain function state.

[0003] However, the existing method for combining MRI and fnirs can be seen in Figure 1 The host computer and the upper computer are placed in the control room, and a waveguide hole is opened on the wall of the scanning room. The optical fiber or wire connected to the head cap worn by the subject is directly connected to the host computer outside the scanning room through the waveguide hole, wherein the control room is far away from the head of the subject. The length of the optical fiber or wire connected to the head cap worn by the subject must reach 4-5 meters, or even 10 meters. The long optical fiber is heavy and causes significant optical attenuation, reducing the accuracy of fnirs detection.

[0004] In addition, in the case of needing the subject to cooperate with EEG (electroencephalogram) and PET (positron emission tomography) modalities, the subject needs to drag the optical fiber of 5-10 meters long to first debug the probe on the head cap and fnirs detection signal in the control room, then drag the long optical fiber to the treatment room to inject medicine, and finally return to the scanning room, which is extremely inconvenient. Since the optical fiber is long, it often needs to be dragged to move, and the long optical fiber is prone to breakage due to the large weight during dragging. Therefore, the fnirs system combined with MRI still has problems such as poor convenience, poor stability, and low accuracy of detection results.

[0005] Especially, after the subject carries the long optical fiber of 5-10 meters into the scanning room, the subject still needs to debug before the detection starts. Since the debugging of the probe on the head cap and the fnirs detection signal itself takes time, combined with the problems of poor stability and low accuracy of the long optical fiber, the debugging efficiency is significantly reduced. SUMMARY

[0006] In view of the above technical problems in the prior art, the present application is provided. The present application provides an fnirs system compatible with an MRI imaging system and having an optimized length of a wire bundle, which can limit the length of an optical fiber bundle and an electric wire bundle connected with a head cap to be below 3 meters, thereby reducing optical attenuation, improving the accuracy of fnirs detection, reducing the self-weight of the optical fiber bundle and the electric wire bundle, improving the portability of a subject carrying the optical fiber bundle and the electric wire bundle connected with the head cap, reducing the possibility of breakage, thereby better compatibility with the MRI, providing effective brain activity information, and the debugging method of the present application can significantly improve the debugging efficiency, improve the use experience of the subject while ensuring the detection accuracy.

[0007] According to the first aspect of the present application, an fnirs system compatible with an MRI imaging system and having an optimized length of a wire bundle is provided, the fnirs system comprising a head cap, an SD probe group arranged on the head cap, and a host computer, wherein the S probe is used to transmit near-infrared light to the subject, the D probe is used to receive near-infrared light from the subject, and the head cap and the SD probe group do not contain ferromagnetic materials and can be placed in the scanning hole of the MRI imaging system; the host computer specifically comprises a group of APD devices, a main processor and a processing circuit, wherein each APD device is respectively arranged to be connected to the corresponding D probe on the head cap via a first optical fiber bundle, the D probe remains connected with the first optical fiber bundle to receive the near-infrared light emitted from the head of the subject and convert it into an electrical signal; the main processor and the processing circuit are arranged to be electrically connected to the group of APD devices to process the electrical signal to obtain fnirs detection data, wherein the S probe remains connected with a second optical fiber bundle or a second electric wire bundle to be connected to the host computer via the second optical fiber bundle or the second electric wire bundle, the length of the first optical fiber bundle is below 3 meters, and the length of the second optical fiber bundle or the second electric wire bundle is also below 3 meters.

[0008] According to a second aspect of the present application, a debugging method of an fnirs system compatible with an MRI imaging system and having an optimized length of a wire bundle is provided, the debugging method comprising: setting a test host in a scanning room configured with the MRI imaging system, and setting a debugging host in a target area outside the scanning room; plugging a second optical fiber bundle or a second electric wire bundle connected with an S probe on a head cap worn by a subject into the debugging host, and after plugging a first optical fiber bundle connected with a D probe on the head cap into the debugging host, a length of the first optical fiber bundle is below 3 meters, and a length of the second optical fiber bundle or the second electric wire bundle is also below 3 meters; obtaining first fnirs detection data transmitted by the debugging host, and debugging a fit of each probe on the head cap to a scalp of the subject based on the first fnirs detection data; after the debugging ends, unplugging the optical fiber bundle or the electric wire bundle plugged into the debugging host, and plugging the second optical fiber bundle connected with the S probe into the test host, and plugging the first optical fiber bundle connected with the D probe into the test host again, and then performing second fnirs detection; obtaining second fnirs detection data transmitted by the test host, and debugging the fit of each probe on the head cap to the scalp of the subject based on the second fnirs detection data.

[0009] Compared with the prior art, the embodiment of the present application has the following beneficial effects:

[0010] The fnirs system compatible with the MRI imaging system and having the optimized length of the wire bundle provided by the embodiment of the present application comprises a head cap, an SD probe group arranged on the head cap, and a host, wherein the host comprises a group of APD devices, each APD device is arranged to be connected to a corresponding D probe on the head cap via a first optical fiber bundle, an S probe is connected with a second optical fiber bundle or a second electric wire bundle, and is connected to the host via the second optical fiber bundle or the second electric wire bundle. Moreover, a length of the first optical fiber bundle is below 3 meters, and a length of the second optical fiber bundle or the second electric wire bundle is also below 3 meters. In this way, the first optical fiber bundle and the second optical fiber bundle, or the first optical fiber bundle and the second electric wire bundle are both limited to below 3 meters, which greatly shortens the length of the optical fiber bundle and the electric wire bundle connected with the head cap, effectively reduces the optical attenuation of the optical fiber bundle, and is beneficial to improve the accuracy and stability of fnirs detection.

[0011] Moreover, in the scenario that the subject needs to carry the optical fiber connected with the head cap for movement, the embodiment of the present application limits the length of the optical fiber bundle and the electric wire bundle connected with the head cap to below 3 meters, which can effectively reduce the self-weight of the optical fiber bundle and the electric wire bundle, greatly improve the portability of movement, significantly reduce the possibility of breakage of the optical fiber bundle during movement, and effectively reduce the physical burden and psychological burden of the subject.

[0012] In particular, the subject can carry a shorter optical fiber or wire outside the scanning room, and the fnirs detection signal of the probe on the head cap is debugged through the debugging host, after debugging, the subject carries the shorter optical fiber or wire back to the scanning room, and plugs the optical fiber or wire into the test host placed in the scanning hole, and fine-tunes again. It can be seen that the fnirs system debugging method provided by the embodiment of the application can significantly improve the debugging efficiency of the probe on the head cap and the fnirs detection signal, greatly shorten the debugging time of the subject in the scanning room, and improve the use experience of the subject.

[0013] The above description is only a summary of the technical solutions of the present application, in order to more clearly understand the technical means of the present application, the specific embodiments of the present application can be implemented according to the content of the specification, and in order to make the above description and other purposes, characteristics and advantages of the present application more obvious and easy to understand, the following specific embodiments of the present application are described. BRIEF DESCRIPTION OF DRAWINGS

[0014] In the drawings, which are not necessarily drawn to scale, like numerals can describe similar components in different views. Like numerals having different letter suffixes can represent different instances of similar components. The drawings illustrate generally, by way of example, various embodiments discussed in the specification, and together with the description, serve to explain principles of the disclosed embodiments. Such embodiments are illustrative and exemplary, but not exhaustive or exclusive, of the methods, apparatus, systems or non-transitory computer readable medium having instructions for implementing the method.

[0015] Figure 1 A schematic diagram of the configuration of the fnirs system compatible with the MRI imaging system according to the prior art is shown.

[0016] Figure 2 A schematic diagram of the fnirs system compatible with the MRI imaging system and having an optimized beam length provided by the embodiment of the present application is shown.

[0017] Figure 3 A schematic diagram of the configuration of the host in the fnirs system compatible with the MRI imaging system and having an optimized beam length provided by the embodiment of the present application is shown.

[0018] Figure 4 Another schematic diagram of the configuration of the host in the fnirs system compatible with the MRI imaging system and having an optimized beam length provided by the embodiment of the present application is shown.

[0019] Figure 5 A schematic diagram of the spatial variation of the gradient magnetic field in the MRI imaging system according to the embodiment of the present application is shown.

[0020] Figure 6 A schematic diagram showing a host placement in a scan bore in an fnirs system compatible with MRI imaging system and having optimized beam length according to an embodiment of the present application.

[0021] Figure 7 A schematic diagram showing yet another configuration of an fnirs system compatible with MRI imaging system and having optimized beam length according to an embodiment of the present application.

[0022] Figure 8 A schematic diagram showing a configuration of a bundle interface, a fiber bundle connector and an electrical wire bundle connector according to an embodiment of the present application.

[0023] Figure 9 A schematic diagram showing a configuration of a first mounting rack inside a host according to an embodiment of the present application.

[0024] Figure 10 A schematic diagram showing another configuration of an fnirs system compatible with MRI imaging system and having optimized beam length according to an embodiment of the present application.

[0025] Figure 11 A flow chart showing a commissioning method of an fnirs system compatible with MRI imaging system and having optimized beam length according to an embodiment of the present application. DETAILED DESCRIPTION

[0026] In order to make the skilled in the art better understand the technical solutions of the present application, the present application is described in detail below in combination with the drawings and specific embodiments. The embodiments of the present application are further described in detail below in combination with the drawings and specific embodiments, but not as a limitation to the present application.

[0027] The "first", "second" and similar words used in the present application do not represent any order, quantity or importance, but are only used for differentiation and convenience in expression, but not rigidly limited to "first" and "second". The "first" and "second" can be interchangeable. The "including" or "containing" and similar words used in the present application mean that the elements before the word cover the elements listed after the word, and do not exclude the possibility of also covering other elements. In the present application, the arrows shown in the figures are only examples of the execution order, but not a limitation, and the technical solutions of the present application are not limited to the execution order described in the embodiments. The steps in the execution order can be combined, can be decomposed, can be exchanged in order, as long as the logical relationship of the execution content is not affected.

[0028] All the terms used in the present application, including technical terms or scientific terms, have the same meaning as understood by the ordinary skilled person in the field to which the present application belongs, unless otherwise specifically defined. It should also be understood that terms defined in general dictionaries should be interpreted to have meanings consistent with their meanings in the context of the relevant technology, and should not be interpreted in an idealized or excessively formalized sense, unless otherwise defined explicitly herein. Techniques and equipment known to those of ordinary skill in the relevant art can not be discussed in detail, but in appropriate cases, the techniques and equipment should be considered part of the specification.

[0029] In some embodiments of the present application, an fnirs system compatible with an MRI imaging system and having an optimized beam length is provided, which combines Figures 2-4 The fnirs system is described.

[0030] The fnirs system includes a head cap 201 and an SD probe group 202 arranged on the head cap 201, the S probe and the D probe in the SD probe group 202 having different functions, wherein the S probe is used to transmit near-infrared light to the subject, and the D probe is used to receive near-infrared light from the subject, and the head cap 201 and the SD probe group 202 do not contain ferromagnetic materials so as to be placed in the scanning hole of the MRI imaging system, so as to avoid the ferromagnetic materials interfering with the magnetic field distribution, affecting the normal imaging of the MRI equipment, and affecting the accuracy and stability of the detection.

[0031] The fnirs system further includes a host computer 203, which specifically includes a group of APD devices 301, a main processor 303, and a processing circuit 302. Each APD device is configured to be connected to a corresponding D probe on the head cap via a first optical fiber bundle, and the D probe remains connected with the first optical fiber bundle to receive the near-infrared light emitted from the head of the subject and convert it into an electrical signal.

[0032] Specifically, each APD device, i.e. Avalanche Photodiode, is connected with the corresponding D probe on the headgear through the first optical fiber bundle. It can be understood that the APD device can be directly connected with the corresponding D probe on the headgear through the first optical fiber bundle, i.e. the D probe remains connected with the first optical fiber bundle, and the APD device is also directly connected with the first optical fiber bundle; or the APD device can be indirectly connected with the corresponding D probe on the headgear through the first optical fiber bundle, i.e. the D probe remains connected with the first optical fiber bundle, and the APD device is indirectly connected with the first optical fiber bundle, for example, a coupling device and another segment of optical fiber bundle are added between the APD device and the first optical fiber bundle, etc., and the embodiments of the present application do not make specific limitation on the connection mode between the APD device and the first optical fiber bundle. The optical fiber bundle has good light transmission characteristics and can efficiently transmit the near-infrared light emitted from the corresponding D probe on the headgear of the subject to the APD device. This connection mode can ensure that the near-infrared light has less loss during transmission and can accurately guide the near-infrared light to the corresponding APD device for detection, while reducing the mutual interference between the lines exposed in the scanning hole (because it is an optical fiber bundle) and the magnetic field.

[0033] In this embodiment, the host 203 further includes a main processor 303 and processing circuit 302 configured to be electrically connected to the set of APD devices 301 to process the electrical signals to obtain fnirs detection data.

[0034] Specifically, after the APD device converts the received near-infrared light emitted from the head of the subject into electrical signals, the APD device transmits these electrical signals to the main processor 303 and processing circuit 302 through electrical connection. These electrical signals contain physiological information related to the tissues of the head of the subject, but the electrical signals can be relatively weak and can be mixed with noise and other interference factors. The main processor 303 and processing circuit 302 perform a series of processing operations on the received electrical signals, including: amplifying the signals to improve the strength of the signals to a level that can be effectively analyzed; filtering operation to remove high-frequency noise or other irrelevant interference components in the signals to improve the quality of the signals; analog-to-digital conversion to convert continuous analog electrical signals into digital signals for further analysis and processing by computers or other digital processing devices. In addition, it can also include processing steps such as feature extraction and data correction of the signals to highlight the feature information related to fnirs detection.

[0035] In some embodiments of the present application, the S probe keeps connected with a second fiber bundle or a second wire bundle to be connected to the host 203. The length of the first fiber bundle is below 3 meters, and the length of the second fiber bundle or the second wire bundle is also below 3 meters. It can be understood that the connection between the second fiber bundle or the second wire bundle and the host 203 can be direct connection or indirect connection, for example, adding a coupling device and another section of fiber bundle or wire bundle, and the embodiments of the present application do not make specific limitation on the connection mode between the second fiber bundle or the second wire bundle and the host 203.

[0036] For the convenience of description, the second fiber bundle, the second wire bundle and the first fiber bundle can be collectively referred to as a cable.

[0037] Since the length of the cable is controlled below 3 meters, the optical attenuation can be effectively reduced, and the fnirs detection accuracy can be improved. When the subject keeps wearing the headgear 201 connected with the cable to move in and out of the scanning room, since the length of the cable is below 3 meters, the self-weight of the cable is reduced, the cable can be effectively prevented from being broken in the dragging process, and the subject can more conveniently move in and out of the scanning room.

[0038] In some embodiments, the second fiber bundle or the second wire bundle connected with the S probe and the first fiber bundle connected with the D probe are detachably plugged into the host. That is, the cable connected with the probe on the headgear 201 worn by the subject is detachably plugged into the host 203. For example, when the subject lies in the scanning hole, the cable connected with the probe on the headgear 201 is plugged into the host 203, and when the subject wants to leave the scanning room, the cable plugged into the host 203 can be directly unplugged to disconnect the cable from the host 203, thereby improving the operation convenience.

[0039] In some embodiments, the host 203 is packaged in a shielding shell 304 to be placed in a predetermined space range of the isocenter periphery in the scanning hole of the MRI imaging system. The shielding shell 304 is made of a non-ferromagnetic metal, and metals such as aluminum, copper, gold and silver are non-ferromagnetic metals. In a preferred embodiment, the non-ferromagnetic metal is aluminum, which is low in price and light in density and mass, and is convenient for installation and movement. The shielding shell 304 made of aluminum can effectively shield the strong magnetic field generated by the MRI imaging system and the electromagnetic waves in the surrounding environment.

[0040] Figure 2 It is shown that the host 203 is placed in the scanning hole. In some embodiments, the size of the shielding shell 304 is suitable for being placed in the scanning hole of the MRI imaging system to operate in the space range of the periphery of the isocenter.

[0041] During the process of acquiring images by MRI, the gradient magnetic field plays a key role in spatial positioning. By applying gradient magnetic field in three directions (usually x direction (transverse direction), y direction (height direction), and z direction (longitudinal direction)), the signal characteristics of different positions in space are different. See Figure 5 The strength of the gradient magnetic field changes with the radial distance from the isocenter (the distance from the isocenter in the x-y cross section), and the gradient magnetic field strength is the smallest at the isocenter, and the farther away from the isocenter, the more obvious the gradient magnetic field changes, and the change rate of the magnetic field strength at the edge of the gradient coil is the largest.

[0042] The size of the shielding shell 304 is suitable for being placed in the isocenter of the scanning hole of the MRI imaging system to operate in the peripheral space range of the isocenter, so as to place the host 203 as centrally as possible in the scanning hole. In this way, the magnetic field change at the position of the host 203 is more gentle, and the induced electromagnetic force and eddy current are smaller, so that the influence of the electromagnetic force on the host 203 can be reduced, the displacement or damage of the components of the host 203 due to the force can be avoided, and the heat generated by the eddy current and the interference with the MRI magnetic field are reduced, which is beneficial to ensure the normal operation of the fnirs device and the quality of the MRI image.

[0043] Exemplarily, a support platform can also be provided in the peripheral space range of the isocenter in the scanning hole to place the related devices such as electroencephalograph amplifiers used with the MRI system, as shown in Figure 2 and Figure 6 The support platform is raised from the bottom of the scanning hole, so that the electroencephalograph amplifiers and the host 203 placed on the support platform are closer to the center of the scanning hole.

[0044] In some embodiments, the package of each APD device is made of a non-ferromagnetic material to avoid interfering with the magnetic field strength of the MRI imaging system, affecting the imaging quality, and damaging the device or causing harm to the subject. The metal used for the pins or plating of each APD device is a first non-ferromagnetic metal.

[0045] In some embodiments, the metal used for the electrical devices and electrical connection lines of the main processor 303 and the processing circuit 302 is a second non-ferromagnetic metal.

[0046] In some embodiments, the first non-ferromagnetic metal and the second non-ferromagnetic metal are copper. Copper has higher electrical conductivity, generates less eddy current and less heat under a changing magnetic field, and has less difference in magnetic permeability with air, which can reduce the interference with the magnetic field, the eddy current effect, heat generation, and signal artifacts.

[0047] The complete MRI imaging system site layout mainly includes a control room (also referred to as an operation room) in which MRI professionals operate the MRI equipment, a scanning room (also referred to as a scanning room) opposite the control room and connected to the control room, that is, a place where a patient receives scanning, a machine room (storing various cabinets related to MRI, including a radio frequency transmission system, a gradient transmission system, a radio frequency receiving and reconstruction system, a magnet refrigeration system, power supply, etc., also referred to as an equipment room) next to the scanning room. The site layout sometimes also includes a workstation (a place where a doctor views and analyzes MRI images) and a treatment room. Sometimes the workstation and the control room can be integrated. When using modalities such as EEG and PET in combination with MRI, the subject is usually given conductive glue or contrast agent in the treatment room.

[0048] In some embodiments, the host computer 203 further includes a communication interface 305 configured to be communicatively connected to the host computer in the control room in a wired manner without introducing ferromagnetic materials, to transmit fnirs detection data to the host computer.

[0049] That is, after a series of processes, the host processor 303 and the processing circuit 302 convert the original electrical signal into fnirs detection data, which is transmitted to the host computer in the control room in a wired manner through the communication interface 305, so that the host computer can analyze the fnirs detection data to obtain physiological parameters related to blood oxygen parameters, blood flow changes, etc. in the form of numerical values, waveforms or images.

[0050] In some embodiments, the host computer 203 further includes a light source part for transmitting near-infrared light to the corresponding S probe on the headgear 201 via the second optical fiber bundle, or a light source driving part for connecting to each near-infrared LED at the corresponding S probe on the headgear 201 via the second wire bundle to make the near-infrared LED emit near-infrared light, the light source part or the light source driving part 306 operates under the control of the host processor 303 and the processing circuit 302, and the light source part or the light source driving part 306 does not contain ferromagnetic materials.

[0051] Specifically, in the case that no electronic devices are arranged in the corresponding S probe on the headgear 201 worn by the subject, the light source part emits near-infrared light, and transmits the near-infrared light to the corresponding S probe on the headgear 201 via the second optical fiber bundle. In the case that near-infrared LEDs are installed in the corresponding S probe on the headgear 201 worn by the subject, the light source driving part can transmit driving signals to each near-infrared LED at the corresponding S probe on the headgear 201 via the second wire bundle, and each near-infrared LED generates near-infrared light based on the driving signals.

[0052] The main processor 303 and the processing circuit 302 can generate corresponding control logic and instructions according to preset programs or algorithms, and the instructions are transmitted to the light source part or the light source driving part 306 to drive the near-infrared LED to emit light according to the instructions.

[0053] In some embodiments, as Figure 4 The processing circuit 302 includes an anti-aliasing filter 310 configured to perform a low-pass operation with a cutoff frequency lower than the lower limit of the frequency of the radio frequency (RF) signals emitted by the MRI imaging system and higher than twice the upper limit of the frequency of the near-infrared brain function imaging detection signal, and the stopband attenuation is greater than a predetermined dB number. The MRI imaging system emits radio frequency (RF) signals with a wide frequency range. The anti-aliasing filter 310 sets the cutoff frequency lower than the lower limit of the frequency of the radio frequency (RF) signals emitted by the MRI imaging system to effectively prevent the RF signals of the MRI from entering the processing circuit 302 of the host 203, thereby avoiding interference with the near-infrared brain function imaging detection signal.

[0054] The cutoff frequency of the anti-aliasing filter 310 is set to be higher than twice the upper limit of the frequency of the near-infrared brain function imaging detection signal, so that the integrity and accuracy of the signal can be ensured when the detection signal is sampled and processed, and high-frequency noise and other interference signals are prevented from passing through the filter, thereby improving the signal-to-noise ratio and resolution of the system and ensuring the quality of the near-infrared brain function imaging detection signal. For example, the cutoff frequency of the anti-aliasing filter 310 can be set to 100 Hz to 10 kHz, which can effectively filter out the RF signals of the MRI and well preserve the near-infrared brain function imaging detection signal.

[0055] In some embodiments, the processing circuit 302 further includes an amplifier and an analog-to-digital converter 311, and the amplifier is used to receive a differential input signal to suppress common-mode interference caused by the MRI magnetic field. When the amplifier receives the differential input signal, subtraction operation is performed on the two input signals. Since the common-mode interference has substantially the same size and phase on the two lines, the common-mode interference signal is greatly weakened or even completely canceled out during the subtraction process. The useful differential signal is normally amplified. In this way, the amplifier effectively suppresses the common-mode interference caused by the MRI magnetic field through processing of the differential input signal, thereby improving the quality and stability of the signal.

[0056] In some embodiments, the processing circuit 302 further includes an electrostatic discharge protection unit 309 configured to prevent electrostatic hazards caused by plugging of the second wire harness and ensure the normal operation of the system and the stability of signal transmission.

[0057] The electrostatic discharge protection unit 309 can limit the voltage and current during electrostatic discharge by employing a series of electrostatic protection measures, such as installing electrostatic discharge resistors and transient voltage suppressor diodes (TVS). When static electricity is generated and accumulates to a certain level, the electrostatic discharge protection unit 309 can quickly guide the static electricity to the ground or limit the transient high voltage generated by electrostatic discharge to a safe range, thereby protecting electronic components from electrostatic hazards and ensuring the normal operation of the system and the stability of signal transmission.

[0058] For example, such as Figure 2 As shown, when the main unit 203 is placed in the center of the scanning aperture, it needs to be encapsulated in a shielded housing. A cable less than 3 meters long can connect to the various probes on the headgear 201 while also connecting to the main unit 203. Because the cable length is limited to less than 3 meters, the load on the subject's head is reduced. After wearing the headgear, the subject can easily detach from the main unit 203 or carry the main unit 203 freely inside and outside the scanning room.

[0059] Specifically, the communication connection between the host computer 203 and the host computer can be disconnected, while keeping the host computer 203 and the cable connected. In this case, the patient can carry the host computer 203 into and out of the control room and adjust the various probes on the headgear 201 worn by the patient. If the patient needs to cooperate with EEG and PET modalities, after adjustment, the patient also needs to carry the cable to the treatment room for medication, then, while still wearing the headgear, carry the host computer 203 into the scanning room, place the host computer 203 into the scanning port, and connect the host computer 203 to the host computer.

[0060] Placing the main unit 203 inside the scanning aperture significantly shortens the cable length connecting the SD probe assembly 202 on the head cap 201 to the main unit 203. The cable length only needs to be less than 3 meters, such as 2.5 meters, 2 meters, 1.5 meters, 1 meter, or 0.5 meters. Keeping the cable length below 3 meters effectively reduces light attenuation, improves the accuracy of FINRSS detection, and makes it more convenient to use.

[0061] In other embodiments, the FNIRS system includes a near-infrared optical coupling device, such as... Figure 7 As shown, the near-infrared optical coupling device 701 is placed in the scanning chamber and connected to the host 203. The second optical fiber bundle or the second wire bundle, which is connected to the S probe, and the first optical fiber bundle, which is connected to the D probe, are detachably plugged into the near-infrared optical coupling device 701.

[0062] Specifically, the host 203 can be placed in the control room, and a waveguide hole can be opened on the wall of the scanning room to enable the cable connected with the host 203 to pass through the waveguide hole and be connected to the near-infrared light coupling device 701 in the scanning room. In this case, the near-infrared light coupling device 701 placed in the scanning room can serve as an adapter, and the second optical fiber bundle or the second wire bundle connected with the S probe and the first optical fiber bundle connected with the D probe are only the cables between the SD probe group 202 and the near-infrared light coupling device 701, and the lengths of the cables are all less than 3 meters. The placement position of the near-infrared light coupling device 701 in the scanning room can be fixed and unchanged, and the near-infrared light coupling device 701 does not need to be moved arbitrarily, and therefore, the length of the cable for the communication connection between the near-infrared light coupling device 701 and the host 203 is not limited, and in order to reduce the light attenuation as much as possible, the length of the cable between the near-infrared light coupling device 701 and the host 203 is as short as possible.

[0063] In this embodiment, even if the host 203 is not placed in the scanning room, by arranging the near-infrared light coupling device 701 as an adapter in the scanning room, the cable connected with the probe on the headgear worn by the examinee only needs to be plugged with the near-infrared light coupling device 701, and in this case, the length of the cable can still be controlled to be less than 3 meters. When the examinee needs to go to the control room or the treatment room or other areas outside the scanning room, the cable can be directly pulled out of the near-infrared light coupling device 701, and the examinee can conveniently go in and out of the scanning room while wearing the headgear together with the cable.

[0064] Exemplarily, taking the S probe connected with the second optical fiber bundle as an example, a light guide between a pair of input optical fiber-output optical fiber can be arranged in the near-infrared light coupling device 701. The function of the light guide is to guide the transmission of the optical signal between the input optical fiber and the output optical fiber, so as to ensure that the optical signal can be accurately transmitted from the first optical fiber bundle connected with the D probe to the optical fiber bundle part connected with the host 203 or from the optical fiber bundle part connected with the host 203 to the second optical fiber bundle connected with the S probe, so as to realize the effective transmission of the optical signal. Meanwhile, a limiting structure can be arranged in the near-infrared light coupling device 701 to maintain the fixed optical coupling relationship between the input optical fiber-light guide-output optical fiber. That is, the limiting structure can ensure the stable relative position between the three, so as to ensure that the optical signal will not be disturbed in the transmission process due to the movement or misalignment of the components, thereby maintaining the stability and accuracy of the system optical signal transmission, and making the detection result more reliable. When the S probe is connected with the second wire bundle, only a group of conductive pieces instead of a group of light guides arranged in the near-infrared light coupling device 701 are needed to ensure that the electrical signal can be transmitted from the wire bundle part connected with the host 203 to the second wire bundle connected with the S probe, and details are not described herein again.

[0065] In some embodiments, only a limiting structure can be arranged between the input fiber and the output fiber inside the near-infrared light coupling device 701, the input fiber and the output fiber are directly optically coupled to realize the transmission of optical signals, and the limiting structure maintains the fixed optical coupling relationship between the input fiber and the output fiber.

[0066] In some embodiments, the distal end of the second optical fiber bundle or the second wire bundle connected with the S probe and the distal end of the first optical fiber bundle connected with the D probe are gathered into a bundle connector, wherein the distal end only represents the direction relative to the position of the probe, for example, the direction close to the position of the probe is the proximal end, and the direction away from the position of the probe is the distal end. The bundle connector can be split or integrated, and the embodiments of the present application do not make specific limitations thereto.

[0067] Specifically, as shown in Figure 8 The bundle connector includes an array of wire bundle connectors 802 and optical fiber bundle connectors 801, wherein the optical fiber bundle connectors 801 can only include the first optical fiber bundle connector, or can include the first optical fiber bundle connector and the second optical fiber bundle connector. In the case that the optical fiber bundle connector 801 includes the first optical fiber bundle connector and the second optical fiber bundle connector, the arrangement positions of the first optical fiber bundle connector and the second optical fiber bundle connector are not limited, and can be arranged according to the different positions and numbers of the first optical fiber bundle and the second optical fiber bundle connected with the probes on the head cap.

[0068] The wire bundle connector 802 can only be the second wire bundle connector, for example, in the case that the second wire bundle is connected with the S probe, the bundle connector includes the wire bundle connector 802 into which the distal end of the second wire bundle is gathered and the optical fiber bundle connector 801 into which the distal end of the first optical fiber bundle is gathered.

[0069] Specifically, the bundle connector is detachably plugged into the bundle interface of the near-infrared light coupling device, and the bundle interface includes an array of bundle interfaces 803, wherein each bundle interface 803 corresponds to each connector in the bundle connector.

[0070] Figure 8 The bundle interface 803 shown in the middle includes an optical fiber bundle interface corresponding to the optical fiber bundle connector 801 and a wire bundle interface corresponding to the wire bundle connector 802. Of course, in the case that the second optical fiber bundle is connected with the S probe, the bundle connector can only include the optical fiber bundle connector 801, and the bundle interface 803 can only have the optical fiber bundle interface without the wire bundle interface. Only as an example, the bundle interface 803 can be arranged according to the bundle connector.

[0071] In some embodiments, the fiber bundle connector 801 comprises a second mounting rack 805 and a set of fiber structure heads 804 integrally formed with the second mounting rack 805; or, the fiber bundle connector 801 comprises a second mounting rack 805 and a set of fiber structure heads 804 detachably screwed on the second mounting rack 805. The second mounting rack 805 is further provided with at least two screws, and each fiber structure head 804 is fixed with an optical fiber. The fiber bundle connector is provided with a set of notches corresponding to the fiber structure heads 804 and at least two threaded holes. When the fiber structure heads 804 are inserted into the corresponding notches, the screws are screwed into the corresponding threaded holes to complete the firm insertion of the fiber bundle connector 801 and the fiber bundle connector.

[0072] By arranging the bundling connector part at the distal end of the cable and the bundling connector part on the near-infrared light coupling device, the cable can be conveniently plugged into and pulled out of the near-infrared light coupling device, and the cable can be ensured to be correctly plugged into the near-infrared light coupling device, the stability of the connection between the cable and the near-infrared light coupling device is maintained, the problem of debugging error caused by incorrect plugging of the cable is avoided, and the problem of low debugging efficiency is reduced.

[0073] In some embodiments, the host further comprises a first mounting rack arranged in the shell, and the shell comprises a shielded shell or a non-shielded shell. When the near-infrared light coupling device is placed in the scanning chamber and connected to the host, the shell of the host can be a non-shielded shell. The first mounting rack is provided with a slot hole, the APD is embedded in one end of the slot hole, the inner wall of the slot hole is provided with a limiting thread, and the notches on the fiber bundle connector are arranged in one-to-one correspondence with the APDs.

[0074] Exemplarily, as Figure 8 and Figure 9 The light receiving end of the fiber structure head 804 can be connected to a D probe, and the light emitting end of the fiber structure head 804 can be inserted into the slot hole on the first mounting rack 901 through the notch on the fiber bundle connector and directly connected to the APD 902. Each fiber structure head 804 is fixed with an optical fiber, and the fiber structure head 804 is inserted into the corresponding notch to transmit an optical signal to the APD 902.

[0075] Specifically, the light emitting end of the fiber structure head 804 and the APD 902 can form a space therebetween, and a filter can be arranged in the space to filter out interference light other than near-infrared light.

[0076] The APD 902 can be stably arranged by the first mounting rack 901, so that the APD 902 and the fiber structure head 804 can maintain a relatively stable positional relationship.

[0077] The above-mentioned first mounting rack 901 can be configured in a plate shape, and the slot holes formed therein can be arranged in one-to-one correspondence with the APD 902.

[0078] Since the APD 902 generates heat during operation, and the change of magnetic field in the scanning room also causes the metal to heat up, the temperature and heat itself can affect the working condition of the APD 902, and the temperature sensor 903 can be used to monitor the heat generation of the APD 902 in real time. In some embodiments, the first mounting bracket 901 is made of ceramic matrix composite material, polyimide or carbon fiber. These materials do not interfere with the magnetic field during MRI scanning and do not produce artifacts, and have good thermal conductivity and hardness, which are suitable for use in the MRI scanning room.

[0079] In some embodiments, a plurality of temperature sensors 903 are embedded in the first mounting bracket 901, and each APD 902 surrounds and is adjacent to a corresponding temperature sensor 903. In this way, the temperature of the APD 902 is indirectly monitored by monitoring the temperature of the heat conductor, i.e. the first mounting bracket 901, which is in sufficient heat exchange with the APD 902, by using the temperature sensor 903.

[0080] In some embodiments, the surface of the first mounting bracket 901 can be perpendicular to the axial direction of the optical fiber structure head 804.

[0081] Exemplarily, the light emitting end of the optical fiber structure head 804 can be sleeved with a threaded part, which can be connected with the first mounting bracket 901 through threads, so that the optical fiber structure head 804 can be mounted to the first mounting bracket 901 through the threaded part.

[0082] In some embodiments, a limiting thread is arranged in the hole wall of the slot hole of the first mounting bracket 901, i.e. the threaded part of the optical fiber structure head 804 cannot continue to enter inwardly after entering the position of the limiting thread. After the APD 902 is embedded in one end of the slot hole, there is a certain gap, such as 1mm, between the APD 902 and the limiting thread. In this way, by positioning through the limiting thread, it can be avoided that the APD 902 is crushed and broken when the optical fiber structure head 804 is mounted to the first mounting bracket 901, and the distance between the APD 902 and the optical fiber structure head 804 can also be limited to avoid affecting the light coupling efficiency due to too far distance.

[0083] In some embodiments, each wire of the second wire harness includes a shielding layer, and the shielding layer is driven by a voltage follower. By using the voltage follower to drive the shielding layer, the potential fluctuation on the shielding layer can be effectively reduced, and the electromagnetic interference caused by the potential change can be reduced. At the same time, the high input impedance of the voltage follower can avoid the load effect on the circuit connected thereto, and ensure the stability of the reference voltage source or the related potential. In the scanning room, the shielding layer of the wire is driven by the voltage follower instead of being directly grounded, which can more effectively suppress the common mode interference signal caused by the strong magnetic field to the wire, ensure the transmission quality of the electrical signal, and improve the reliability and accuracy of the detection system.

[0084] In some embodiments, as shown in FIG. 1, the host computer 203 is disposed in a machine room, and the fnirs system further comprises a host computer 1001 in a control room, and the MRI imaging system comprises a scan hole. Figure 10

[0085] Specifically, a scan bed is placed in the scan room, and the subject lies on the scan bed to enter the scan hole so as to be scanned and imaged by the MRI imaging device. Among them, for the safety of the subject, usually when scanning, the subject's feet are towards the control room and the head is towards the opposite side, so that the operator in the control room can conveniently see the subject and the operation of the equipment in the scan room in the field of view. Thus, the magnet of the scan bed is far away from the control room, and the opposite side towards the head is often arranged in the machine room, so that the distance from the machine room is usually not more than 3 meters.

[0086] The walls of many machine rooms are pre-provided with waveguide holes, which can be directly used. Exemplarily, the host computer 203 can be directly disposed in the machine room close to the head of the subject, at this time, the cable connected with the probe on the head cap worn by the subject passes through the waveguide hole and is connected to the host computer 203 in the machine room, and the length of the cable connected with the probe on the head cap can also be limited to be lower than 3 meters. In this way, the various parts of the system can be better connected and cooperated, and it can be ensured that the fnirs system can be conveniently cooperated with the MRI device under the condition that the first optical fiber bundle, the second optical fiber bundle and the second electric wire bundle are all lower than 3 meters in length, thereby improving the detection efficiency and stability.

[0087] Figure 11 A flowchart of a debugging method of the fnirs system compatible with the MRI imaging system and having an optimized wire bundle length is shown, and the debugging method is specifically shown in steps S1101-S1105. The arrows shown in the figure are only examples of the execution order, and are not limited, and the technical solution of the present application is not limited to the execution order described in the embodiments. Each step in the execution order can be combined, can be decomposed, and can be exchanged in order, as long as the logical relationship of the execution content is not affected.

[0088] In step S1101, a test host computer is disposed in a scan room configured with an MRI imaging system, and a debugging host computer is disposed in a target area outside the scan room. The target area can be a control room or a treatment room outside the control room, and is not limited. Preferably, the target area is in the control room. Moreover, the test host computer and the debugging host computer are completely the same in model.

[0089] ​In step S1102, after the second fiber bundle or the second wire bundle connected with the S probe on the head cap of the subject is plugged into the debugging host, and the first fiber bundle connected with the D probe on the head cap is plugged into the debugging host, the first fnirs detection is performed, the length of the first fiber bundle is below 3 meters, and the length of the second fiber bundle or the second wire bundle is also below 3 meters.

[0090] In step S1103, the first fnirs detection data transmitted by the debugging host is acquired, and the fitting of each probe on the head cap to the scalp of the subject is debugged based on the first fnirs detection data. Specifically, the debugging host transmits the first fnirs detection data to the upper computer, the upper computer performs data analysis based on the first fnirs detection data to obtain the signal intensity of the channel corresponding to each probe on the head cap, and analyzes the fitting of each probe to the scalp of the subject according to the signal intensity of each channel. For example, if the signal intensity of a channel corresponding to a probe is weak, the probe can be pressed gently to make the probe fit the scalp.

[0091] In step S1104, after the debugging is completed, the fiber bundle or the wire bundle plugged into the debugging host is unplugged, the second fiber bundle connected with the S probe is plugged into the test host, and the first fiber bundle connected with the D probe is plugged into the test host, and then the second fnirs detection is performed again.

[0092] The debugging method of the fnirs system compatible with the MRI imaging system and having an optimized wire bundle length provided by the embodiments of the present application is applicable to the fnirs system compatible with the MRI imaging system and having an optimized wire bundle length described in the embodiments of the present application.

[0093] Specifically, the length of the fiber bundle and the wire bundle is below 3 meters, and the subject can conveniently carry the fiber bundle and the wire bundle in and out of the scanning room. After the subject adjusts the fitting of each probe on the head cap to the scalp in the target area, the cable connected with the debugging host is unplugged, at this time, the subject can easily carry the fiber bundle and the wire bundle from the target area into the scanning room, and plug the cable into the test host in the scanning room again to perform the second fnirs detection.

[0094] In step S1105, the second fnirs detection data transmitted by the test host is acquired, and the fitting of each probe on the head cap to the scalp of the subject is debugged based on the second fnirs detection data. That is, after the subject returns to the scanning room, only the fine adjustment of each probe on the head cap according to the second fnirs detection data is needed, without entering the scanning room to start debugging from zero, thereby reducing the debugging time and improving the debugging efficiency.

[0095] In this whole process, since the length of the cable is limited to below 3 meters, not only can the cable be prevented from being broken when the examinee enters or exits the scanning room, but also the optical attenuation can be reduced and the convenience of the examinee carrying the cable to move can be improved. Moreover, generally, when the number of examinees waiting for debugging is large, a queue is often needed. Based on the debugging method provided in the embodiments of the present application, the examinee can debug during the waiting for the previous person to be detected, and fine-tune after entering the scanning room, which greatly shortens the detection time, improves the utilization rate of the MRI system, and improves the overall debugging efficiency and debugging accuracy, and improves the use experience of the examinee.

[0096] In some other embodiments, the debugging method further includes that a host is arranged in the target area outside the scanning room, for example, a near-infrared light coupling device is arranged in the scanning room, and the near-infrared light coupling device is connected with the host in the control room; or the host is arranged in the treatment room outside the control room. After the examinee debugs the fnirs system in the control room or the treatment room outside the control room, the examinee enters the scanning room for testing. At this time, the host arranged in the target area outside the scanning room can be used as a debugging host or a testing host.

[0097] Specifically, taking the case that the host is arranged in the control room as an example, the examinee can debug the fitting of each probe on the head cap to the scalp based on the host while waiting in the control room, and then the cable connected with the host is pulled out, and then the examinee carries the optical fiber bundle and the electric wire bundle into the scanning room and plugs the cable into the near-infrared light coupling device in the scanning room, and then fine-tunes each probe on the head cap and performs the second fnirs detection. In this way, the debugging efficiency can also be improved.

[0098] In each of the above embodiments, the processor can be a processing device including one or more general-purpose processing devices, such as a microprocessor, a central processing unit (CPU), a graphics processing unit (GPU), and the like. More specifically, the processor can be a complex instruction set computing (CISC) microprocessor, a reduced instruction set computing (RISC) microprocessor, a very long instruction word (VLIW) microprocessor, a processor operating other instruction sets, or a processor operating a combination of instruction sets. The processor can also be one or more special-purpose processing devices, such as an application specific integrated circuit (ASIC), a field programmable gate array (FPGA), a digital signal processor (DSP), a system on a chip (SoC), and the like.

[0099] This application describes various operations or functions that can be implemented as software code or instructions, or defined as software code or instructions. Such content can be directly executable source code or differential code (“incremental” or “patch” code) (“object” or “executable” form). The software code or instructions can be stored in a computer-readable storage medium and, when executed, can cause a machine to perform the described functions or operations, and include any mechanism for storing information in a machine-accessible form, such as recordable or non-recordable media (e.g., read-only memory (ROM), random access memory (RAM), disk storage media, optical storage media, flash memory devices, etc.).

[0100] Furthermore, although exemplary embodiments have been described herein, their scope includes any and all embodiments based on this application that have equivalent elements, modifications, omissions, combinations (e.g., schemes involving intersections of various embodiments), adaptations, or alterations. Elements in the claims will be interpreted broadly based on the language used in the claims and are not limited to the examples described in this specification or during the implementation of this application, which will be interpreted as non-exclusive. Therefore, this specification and examples are intended to be considered illustrative only, and the true scope and spirit are indicated by the following claims and the full scope of their equivalents.

[0101] The above description is intended to be illustrative and not restrictive. For example, the above examples (or one or more of them) can be used in combination with each other. Other embodiments can be used by those skilled in the art when reading the above description. Furthermore, in the above detailed description, various features may be grouped together to simplify the application. This should not be construed as an intention that a disclosed feature not claimed is necessary for any claim. Rather, the subject matter of the application may be less than all the features of a particular disclosed embodiment. Thus, the claims are incorporated herein by reference as examples or embodiments, wherein each claim is an independent, separate embodiment, and these embodiments are contemplated as being able to be combined with each other in various combinations or arrangements. The scope of this application should be determined by reference to the appended claims and the full scope of their equivalents.

[0102] The above embodiments are merely exemplary embodiments of this application and are not intended to limit this application. The scope of protection of this application is defined by the claims. Those skilled in the art can make various modifications or equivalent substitutions to this application within its substance and scope of protection, and such modifications or equivalent substitutions should also be considered to fall within the scope of protection of this application.

Claims

1. An fnirs system compatible with an MRI imaging system and having optimized beam length, wherein, The fnirs system comprises: a headgear and a set of SD probes arranged on the headgear, the S probes being configured to transmit near-infrared light to the subject, and the D probes being configured to receive near-infrared light from the subject, the headgear and the set of SD probes being free of ferromagnetic materials so as to be capable of being placed in a scan bore of an MRI imaging system; and a host computer, the host computer specifically comprising: a set of APD devices, each APD device being configured to be connected to a corresponding D probe on the headgear via a first optical fiber bundle, the D probe being held in connection with the first optical fiber bundle to receive near-infrared light emitted from the subject's head and convert the near-infrared light into an electrical signal; a main processor and processing circuitry configured to be electrically connected to the set of APD devices to process the electrical signal to obtain fnirs detection data, wherein the S probes are held in connection with a second optical fiber bundle or a second electrical wire bundle to be connected to the host computer via the second optical fiber bundle or the second electrical wire bundle, a length of the first optical fiber bundle is below 3 meters, and a length of the second optical fiber bundle or the second electrical wire bundle is also below 3 meters; the host computer is arranged in either of the following two arrangements: the host computer is disposed in the scan bore; and the host computer is disposed in a machine room close to the subject's head, the second optical fiber bundle or the second electrical wire bundle held in connection with the S probes and the first optical fiber bundle held in connection with the D probes are detachably connected to the host computer, and the machine room stores an MRI-related radio frequency transmission system and a gradient transmission system.

2. The compatible MRI imaging system and fnirs system with optimized beam length of claim 1, wherein, in the case that the host computer is disposed in the scan bore, the host computer is packaged in a shielded housing made of a non-ferromagnetic metal to be placed within a predetermined spatial range of an isocenter periphery of the scan bore of the MRI imaging system.

3. The compatible MRI imaging system and fnirs system with optimized beam length of claim 1, wherein, the second optical fiber bundle or the second electrical wire bundle held in connection with the S probes and the first optical fiber bundle held in connection with the D probes are detachably plugged into the host computer.

4. The compatible MRI imaging system and fnirs system with optimized beam length of claim 1, wherein, each electrical wire of the second electrical wire bundle contains a shielding layer, and the shielding layer is driven by a voltage follower.

5. The compatible MRI imaging system and fnirs system with optimized beam length of claim 2, wherein, the host computer further comprises: a communication interface configured to be communicatively connected to a host computer in a control room in a wired manner without introducing ferromagnetic materials to transmit fnirs detection data to the host computer.

6. The compatible MRI imaging system and fnirs system with optimized beam length of claim 5, wherein, the host computer further comprises: a light source part configured to transmit near-infrared light to the corresponding S probes on the headgear via the second optical fiber bundle, or a light source driving part configured to connect to each near-infrared LED at the corresponding S probes on the headgear via the second electrical wire bundle to cause the near-infrared LED to emit near-infrared light, the light source part or the light source driving part being operated under control of the main processor and the processing circuitry, and the light source part or the light source driving part being free of ferromagnetic materials.

7. The compatible MRI imaging system and fnirs system with optimized beam length of claim 1, wherein, in the case that the host computer is disposed in the machine room close to the subject's head, the fnirs system further comprises a host computer in a control room, and the MRI imaging system comprises a scan bore.

8. The compatible MRI imaging system and fnirs system with optimized beam length of claim 1, wherein, the processing circuitry further comprises: an electrostatic discharge protection unit configured to prevent electrostatic hazards caused by plugging and unplugging of the second electrical wire bundle; and an electrostatic discharge protection unit configured to prevent electrostatic hazards caused by plugging and unplugging of the second electrical wire bundle. An anti-aliasing filter is configured to perform low-pass operation at a cut-off frequency lower than a lower limit of a frequency of an RF signal emitted by an MRI imaging system in operation, and higher than twice an upper limit of a frequency of a near-infrared brain function imaging detection signal, and a stopband attenuation is greater than a predetermined dB number. An amplifier is configured to receive a differential input signal to suppress common-mode interference caused by an MRI magnetic field.

9. A method of commissioning an fnirs system compatible with an MRI imaging system and having an optimized beam length, the method comprising: The debugging method comprises: A test host is arranged in a scanning room configured with an MRI imaging system, and a debugging host is arranged in a target area outside the scanning room; A second fiber bundle or a second wire bundle connected with an S probe on a head cap worn by a subject is plugged into the debugging host, and a first fiber bundle connected with a D probe on the head cap is plugged into the debugging host, and then first fnirs detection is performed, a length of the first fiber bundle is less than 3 meters, and a length of the second fiber bundle or the second wire bundle is also less than 3 meters; First fnirs detection data transmitted by the debugging host is acquired, and a fit of each probe on the head cap to a scalp of the subject is debugged based on the first fnirs detection data; After the debugging is completed, the fiber bundle or the wire bundle plugged into the debugging host is unplugged, the second fiber bundle or the second wire bundle connected with the S probe is plugged into the test host, and the first fiber bundle connected with the D probe is plugged into the test host, and then second fnirs detection is performed again; Second fnirs detection data transmitted by the test host is acquired, and a fit of each probe on the head cap to the scalp of the subject is debugged based on the second fnirs detection data.

Images