Medical guide wire

Abstract

The invention provides a medical guide wire which comprises a porous structure and a core wire which are sequentially connected from the far end to the near end, and a plurality of pores are formed in the porous structure. According to the medical guide wire provided by the invention, the porous structure is arranged at the far end, so that the far end of the medical guide wire has better softness, the passing ability of the medical guide wire in a blood vessel is improved, the blood vessel can be prevented from being damaged, and the success rate of an operation is further improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly to a medical guide wire. Background Art

[0002] In surgical treatment, a guide wire is an important instrument in interventional diagnosis and treatment. Whether the guide wire can smoothly pass through the diseased area during the operation plays a crucial role in the success rate of cardiocerebral surgery. If the guide wire is to reach the diseased area smoothly, the tip needs to be soft, easy to bend and deform, and the whole guide wire needs to have excellent supporting force and torque control.

[0003] In the prior art, there are many problems when using guide wire products. For example, the tip of the guide wire is relatively hard, which poses a risk of piercing blood vessels and hemangiomas when the guide wire moves in the body. At the same time, the tip of the guide wire is often difficult to bend into a shape that conforms to the blood vessel morphology, and the shape of the guide wire after forming is difficult to maintain, making it difficult for the guide wire to pass through the curved blood vessel, resulting in an extended operation time and an increased operation risk.

[0004] Therefore, there is an urgent need to provide a medical guide wire that is easy to bend and does not easily damage blood vessels. Summary of the Invention

[0005] The purpose of the present invention is to provide a medical guide wire. The porous structure at the distal end of the guide wire has good softness, which can improve the passing ability of the guide wire in the blood vessel and avoid damaging the blood vessel, thereby improving the success rate of the operation.

[0006] To achieve the above purpose, the present invention provides a medical guide wire, including a porous structure and a core wire connected in sequence from the distal end to the proximal end. A plurality of pores are provided in the porous structure.

[0007] Optionally, at least part of the pores are distributed in the distal region of the porous structure.

[0008] Optionally, the pores are also distributed in the proximal region and / or the middle region of the porous structure.

[0009] Optionally, the inner diameters of at least part of the pores are different.

[0010] Optionally, in the direction of the axis of the porous structure from the distal end to the proximal end, the inner diameter of the pores gradually decreases.

[0011] Optionally, in the direction from the inside to the outside of the cross-section of the porous structure, the inner diameter of the pores gradually decreases.

[0012] Optionally, all the pores are of an elliptical structure, and the size of the pores in the radial direction of the porous structure is greater than the size of the pores in the axial direction of the porous structure.

[0013] Optionally, the porosity of the porous structure gradually decreases in the direction from the distal end to the proximal end along its own axis, and / or the porosity of the porous structure gradually decreases in the direction from the inside to the outside along its own radial direction.

[0014] Optionally, the distal end of the core wire extends into the porous structure and is connected to the porous structure.

[0015] Optionally, the medical guide wire further includes a sheath or a coating, and the sheath or the coating covers and abuts against at least a part of the outer surface of the porous structure.

[0016] Optionally, the sheath or the coating covers all the outer surfaces of the porous structure, or the sheath or the coating covers the area of the outer surface of the porous structure except the distal end.

[0017] Optionally, the length of the area where the porous structure extends out of the sheath in its own axial direction is less than 50 mm.

[0018] Optionally, the porosity of the porous structure is 30% - 80%, and / or the inner diameter of the pores is 1 - 900 μm.

[0019] Optionally, the total length of the porous structure and the core wire in the axial direction of the porous structure is 80 cm - 320 cm, and the length of the porous structure in its own axial direction is 3 cm - 70 cm; the maximum outer diameter of the porous structure and the core wire is 0.008 inch - 0.038 inch.

[0020] Optionally, the material of the porous structure is one or a combination of polyurethane, polyolefin, and polyester, and / or the material of the core wire is a polymer material or a metal material.

[0021] As described above, the present invention provides a medical guide wire, including a porous structure and a core wire connected in sequence from the distal end to the proximal end, and a plurality of pores are provided in the porous structure. Setting a porous structure at the distal end of the guide wire can improve the softness of the distal end of the guide wire, reduce the hardness of the head end of the guide wire, avoid the head end of the guide wire piercing through the blood vessel, and also make the guide wire easy to bend and pass through tortuous blood vessels, which helps the guide wire to reach the lesion site smoothly and improve the success rate of the operation.

[0022] In addition, the material of the porous structure can be selected from any suitable polymer material with thermoplasticity, biocompatibility, and softness at human body temperature. The preparation material of the porous structure is preferably a thermoplastic polymer material, such as one or a combination of polyurethane, polyolefin, and polyester. Such materials can be shaped by heating, are easy to form and have a larger bending angle, and can have good shape retention at room temperature, improving the shaping ability and shape retention ability of the guide wire. Description of the Drawings

[0023] Figure 1 Axial sectional structure schematic diagram of a medical guide wire in a preferred embodiment of the present invention;

[0024] Figure 2 Axial sectional structure schematic diagram of a porous structure and a sheath in a preferred embodiment of the present invention;

[0025] Figure 3 Axial sectional structure schematic diagram of a medical guide wire in another preferred embodiment of the present invention;

[0026] Figure 4 Structure schematic diagram of pores in a preferred embodiment of the present invention;

[0027] Figure 5 Structure schematic diagram of pores in another preferred embodiment of the present invention;

[0028] Figure 6 Axial sectional structure schematic diagram of a medical guide wire in still another preferred embodiment of the present invention.

[0029] In the figure:

[0030] Porous structure 1; core wire 2; pores 3; round holes 31; oval holes 32; sheath 4. Detailed implementation manners

[0031] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments. According to the following description, the advantages and features of the present invention will be clearer. It should be noted that the accompanying drawings are all in a very simplified form and use non-precise scales, only for the purpose of facilitating and clearly assisting in explaining the objectives of the embodiments of the present invention.

[0032] The orientation or positional relationship indicated by the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. is the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present invention.

[0033] As used in this specification, "distal end" generally refers to the end of the medical guide wire that is far from the operator; the term "proximal end" is opposite to the "distal end" and generally refers to the end of the medical guide wire that is close to the operator; the term "axial direction" refers to the extending direction of the axis of the medical guide wire, that is, the extending direction of the axis of the porous structure.

[0034] In the present invention, unless otherwise clearly defined and limited, terms such as "installation", "connection", "fixation" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or integrated; it can be a mechanical connection, an electrical connection, or communication with each other; it can be directly connected, or connected through an intermediate medium, and can be the internal communication of two components or the interaction relationship between two components, unless otherwise clearly defined. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0035] The following will combine the accompanying drawings to elaborate on the exemplary embodiments of the present application in detail. Without conflict, the following embodiments and the features in the embodiments can be mutually supplemented or combined with each other.

[0036] As Figure 1 shown, a preferred embodiment of the present invention provides a medical guide wire, which includes a porous structure 1 and a core wire 2 connected in sequence from the distal end to the proximal end. A plurality of pores 3 are provided in the porous structure 1.

[0037] Setting the porous structure 1 at the distal end of the medical guide wire can improve the softness of the distal end of the medical guide wire, reduce the hardness of the head end of the guide wire, prevent the head end of the guide wire from piercing the blood vessel, and also make the guide wire easy to bend and pass through tortuous blood vessels, which helps the guide wire to reach the lesion site smoothly and improve the success rate of the operation.

[0038] It should be noted that the material of the porous structure 1 can be selected from any suitable polymer material with thermoplasticity, biocompatibility and softness at human body temperature. The preparation material of the porous structure 1 is preferably a thermoplastic polymer material, such as a combination of one or more of polyurethane, polyolefin and polyester. Such materials can be shaped by heating, are easy to form and have a larger bending angle, and can have good shape retention at room temperature, improving the shaping ability and shape retention ability of the guide wire.

[0039] In addition, the material of the core wire 2 is preferably a polymer material or a metal material to make the core wire 2 have sufficient support.

[0040] When the porous structure 1 or the core wire 2 is prepared from a polymer material, due to the low cost of the polymer material and the high processing efficiency, the porous structure 1 or the core wire 2 can be mass-produced after obtaining a mature preparation process, so as to greatly reduce the production cost.

[0041] When the porous structure 1 is prepared from a thermoplastic polymer material, the forming temperature of the porous structure 1 depends on the type and molecular structure of the polymer material. In actual design, the melting point of the porous structure 1 can be changed by changing the type of the polymer material and the molecular weight of the polymer material, and then the forming temperature of the porous structure 1 can be adjusted to process and form the porous structure 1. By providing pores 3 inside the porous structure 1, the flexibility and bending ability of the porous structure 1 can be improved, and thus the porous structure 1 can be more easily processed and formed.

[0042] Furthermore, when preparing the porous structure 1, pores 3 can be obtained in the porous structure 1 by a foaming method, a template method, a 3D printing method or an electrospinning method, and the distribution of the pores 3 in the porous structure 1 can be adjusted by the above methods so that the porous structure 1 obtains the required properties.

[0043] In a preferred example, the distal end of the core wire 2 extends into the porous structure 1 and is connected to the porous structure 1. Among them, the core wire 2 can extend into the proximal region, the middle region or the distal region of the porous structure 1, and preferably the core wire 2 can extend into the proximal region of the porous structure 1 to leave space for the pores 3 inside the porous structure 1.

[0044] It should be understood that the distal region of the porous structure 1 refers to the part of the porous structure 1 located at the distal end, the proximal region of the porous structure 1 refers to the part of the porous structure 1 located at the proximal end, and the middle region of the porous structure 1 refers to the part of the porous structure 1 other than the distal region and the proximal region.

[0045] This application does not limit the connection manner between the porous structure 1 and the core wire 2. In a preferred example, the porous structure 1 is used to bond to the part of the core wire 2 extending into the porous structure 1 during the preparation process. In another preferred example, the porous structure 1 and the core wire 2 can also be bonded by an adhesive.

[0046] More specifically, the porous structure 1 can adhere to the core wire 2 in a molten state, so that the porous structure 1 can be connected to the core wire 2 when cooled to room temperature. During this process, an adhesive can be selected to coat the outer surface of the core wire 2 inserted into the porous structure 1, or the outer surface roughness of the core wire 2 inserted into the porous structure 1 can be increased to make the bonding between the core wire 2 and the porous structure 1 stronger.

[0047] Preferably, at least part of the pores 3 are distributed in the distal region of the porous structure 1, that is, at least part of the pores 3 are located at the distal end of the porous structure 1.

[0048] In a preferred embodiment, the pores 3 are distributed in the distal region of the porous structure 1 so that the distal end of the porous structure 1 is relatively soft and easy to bend, while the middle region and the proximal region of the porous structure 1 are harder and have better supportability.

[0049] Refer toFigure 1 As shown, in another preferred embodiment, in addition to being distributed in the distal region of the porous structure 1, the pores 3 are also distributed in the proximal region or the middle region of the porous structure 1, so as to balance the flexibility and supportability of the porous structure 1.

[0050] In yet another preferred embodiment, the pores 3 are distributed in the proximal region, the middle region and the distal region of the porous structure 1. At this time, the pores 3 are distributed throughout the porous structure 1, which can make the whole porous structure 1 have better softness to ensure that the porous structure 1 can smoothly pass through tortuous blood vessels.

[0051] In a specific example, the pores 3 can be distributed on the part of the porous structure 1 along its own axis except for the core wire 2.

[0052] Preferably, the inner diameters of at least some of the pores 3 are different. Of course, in other cases, the inner diameters of all the pores 3 can also be the same.

[0053] Referring to Figure 1 As shown, in a preferred embodiment, in the direction from the distal end to the proximal end of the axis of the porous structure 1, the inner diameter of the pore 3 gradually decreases. That is, the inner diameter of the pore 3 at the distal end of the porous structure 1 is larger, and the inner diameter of the pore 3 at the proximal end of the porous structure 1 is smaller. With such a configuration, the flexibility of the distal end of the porous structure 1 can be better, and the passing performance of the porous structure 1 in the blood vessel can be improved. At the same time, the strength of the proximal end of the porous structure 1 can be higher, so that the porous structure 1 has better supportability, and further the control force at the proximal end of the porous structure 1 can be transmitted to the distal end.

[0054] Combined with Figure 1 and Figure 2 As shown, in another preferred embodiment, in the direction from the inside to the outside of the cross-section of the porous structure 1, the inner diameter of the pore 3 gradually decreases. That is to say, the inner diameter of the pore 3 inside the porous structure 1 gradually decreases from the inside to the edge. In this way, the inside of the porous structure 1 can be softer, which is convenient for the bending of the porous structure 1. At the same time, the edge strength of the porous structure 1 is higher (that is, the outside of the porous structure 1 is harder), which improves the torsional controllability of the porous structure 1, that is, it is convenient to transmit the torsional force at the proximal end of the porous structure 1 to the distal end.

[0055] The present application does not limit the shape of the pores 3. In a specific example, all the pores 3 are circular structures, that is, the pores 3 are round holes 31 (refer to Figure 1 and Figure 4 ). In other examples, all the pores 3 can also be square holes or special-shaped holes.

[0056] Due to the poor supportability and / or torsional controllability of some guidewires in the prior art, the force conductivity of the guidewire from the proximal end to the distal end is poor, and the control force and torsional force at the proximal end of the guidewire are not easily transmitted to the distal end, making it difficult to control the distal end of the guidewire to smoothly pass through the bifurcated blood vessel at the proximal end.

[0057] Referring to Figure 3 and Figure 5 As shown, in a preferred embodiment, all the pores 3 are elliptical structures, that is, the pore 3 is an elliptical hole 32. The size of the pore 3 in the radial direction of the porous structure 1 is greater than the size of the pore 3 in the axial direction of the porous structure 1. That is, the major axis of the elliptical hole 23 is distributed along the radial direction of the porous structure 1, and the minor axis of the elliptical hole 23 is distributed along the axial direction of the porous structure 1.

[0058] When configured in this way, since the elliptical hole 32 is relatively easy to compress along the direction with a smaller inner diameter (i.e., relatively easy to compress along the axial direction of the porous structure 1), and relatively difficult to compress along the direction with a larger inner diameter (i.e., relatively difficult to compress along the radial direction of the porous structure 1), the porous structure 1 is prone to deform in its own axial direction.

[0059] More specifically, during the process of the porous structure 1 passing through the tortuous blood vessel, when the head end of the porous structure 1 with the elliptical hole 32 contacts the inner wall of the tortuous blood vessel, it is easier to retract in its own axial direction to avoid damage to the blood vessel wall at the head end of the porous structure 1, further improving the softness at the distal end of the porous structure 1 and enhancing the protection ability of the porous structure 1 to the blood vessel. At the same time, the porous structure 1 is difficult to deform in its own radial direction, so that the porous structure 1 is difficult to bend after being subjected to a radial torsional force in the blood vessel, making the strength of the outer wall of the porous structure 1 higher, thereby enhancing the supportability and torsional controllability of the porous structure 1 and improving the delivery ability and torsional control performance of the distal end of the guidewire.

[0060] In actual preparation, the elliptical hole 32 can be prepared in the porous structure 1 by means of external pressure or directional cooling, so that the pore 3 is compressed along the radial direction of the porous structure 1, and the shape of the pore 3 is changed from circular to elliptical.

[0061] More preferably, in the direction from the distal end to the proximal end of the axis of the porous structure 1, the inner diameter of the elliptical hole 32 gradually decreases, which helps to balance the softness at the distal end and the supportability at the proximal end of the porous structure 1.

[0062] Returning to the reference Figure 1 , in a specific embodiment, the porosity of the porous structure 1 gradually decreases along its own axis from the distal end to the proximal end direction, that is, the density of the pores 3 at the distal end of the porous structure 1 is greater than the density of the pores 3 at the proximal end of the porous structure 1. At this time, the porous structure 1 gradually becomes softer from the proximal end to the distal end to further improve the softness at the distal end of the porous structure 1 and the proximal supportability of the porous structure 1. It should be understood that the porosity of the porous structure 1 refers to the percentage of the total volume of the pores 3 in the porous structure 1 in the total volume of the porous structure 1.

[0063] Return reference Figure 2 , in another specific embodiment, the porosity of the porous structure 1 gradually decreases along the direction from the inside to the outside of its own cross-section, so that the center of the porous structure 1 is softer and the outside is harder. The layered design of the porous structure 1 that gradually hardens from the inside to the outside on its own cross-section can make the torsional force of the porous structure 1 better transmitted, further improving the torsional controllability of the porous structure 1.

[0064] Furthermore, the porosity of the porous structure 1 is preferably 30% - 80%, and the inner diameter of the pore 3 is preferably 1 - 900 um.

[0065] In actual design, the performance of each region of the porous structure 1 can be changed by adjusting the porosity of the porous structure 1, the shape of the pores 3 in the porous structure 1, the segmented or layered pore distribution of the pores 3 in the radial and axial directions of the porous structure 1, and the inner diameter of the pores 3 at different positions, so that the porous structure 1 at the distal end of the guide wire takes into account flexibility, supportability and torsional controllability, and thus meets different usage requirements.

[0066] Optionally, the outer surface of the porous structure 1 can be coated with a hydrophilic coating to improve the lubricity of the porous structure 1. In addition, the outer surface of the core wire 2 can be coated with a PTFE coating, so that the core wire 2 can move smoothly in the blood vessel.

[0067] Preferably, the total length of the guide wire (i.e., the porous structure 1 and the core wire 2) in the axial direction of the porous structure 1 is 80 cm - 320 cm, and the length of the porous structure 1 in its own axial direction is 3 cm - 70 cm. The maximum outer diameter of the porous structure 1 and the core wire 2 is 0.008 inch - 0.038 inch. The operator can design the specific structure of the guide wire according to the shape of the diseased blood vessel of different patients.

[0068] Reference Figure 1 and Figure 3 As shown, the medical guide wire further includes a sheath 4, and the sheath 4 covers and abuts against at least part of the outer surface of the porous structure 1, wherein the sheath 4 can be covered on at least one of the proximal region, the middle section region or the distal region of the porous structure 1. The sheath 4 can be used to protect the porous structure 1 to prevent damage and fracture of the porous structure 1 during transportation.

[0069] In a specific example, the outer surface of the sheath 4 can be coated with a hydrophilic coating to improve the lubricity of the sheath 4, which helps the smooth movement of the porous structure 1 in the blood vessel. Preferably, the preparation material of the sheath 4 can be the same as that of the porous structure 1. The sheath 4 is preferably prepared from a thermoplastic polymer material, and for example, lubricious materials such as PTFE, polyurethane or hydrophilic polymer materials can be selected.

[0070] Reference Figure 1As shown, in a preferred embodiment, the shape of the sheath 4 matches the shape of the porous structure 1, and the sheath 4 covers all the outer surfaces of the porous structure 1, that is, the sheath 4 is sleeved on the outer surfaces of the porous structure 1.

[0071] Referring Figure 6 As shown, in another preferred embodiment, the sheath 4 covers the area of the outer surface of the porous structure 1 except the distal end, that is, the outer surface of the porous structure 1 extends out of the sheath 4. In this way, the hardness of the distal end of the porous structure 1 can be further reduced, the head end of the porous structure 1 can be prevented from damaging the blood vessel wall, and the protection ability for the blood vessel can be improved.

[0072] In a relatively preferred example, when the distal end of the porous structure 1 extends out of the sheath 4, a hydrophilic coating (such as a PVP coating, that is, a polyvinylpyrrolidone coating) can be coated on at least part of the outer surface of the area where the porous structure 1 extends out of the sheath 4 to improve the hydrophilicity and lubricity of the distal end of the porous structure 1. In another relatively preferred example, in addition to coating the hydrophilic coating on the outer surface of the area where the porous structure 1 extends out of the sheath 4, a hydrophilic coating can also be coated on at least part of the outer surface of the sheath 4. In addition, preferably, a hydrophilic coating (such as a PTFE coating, that is, a polytetrafluoroethylene coating) can be coated on at least part of the outer surface of the core wire 2, thereby improving the hydrophilicity and lubricity of the core wire 2.

[0073] Preferably, the length of the part of the porous structure 1 extending out of the sheath 4 in its own axial direction is less than 50 mm, so as to take into account the supportability of the porous structure 1 while making the distal end of the porous structure 1 relatively soft.

[0074] In a preferred embodiment, the medical guide wire may only include a coating, and the coating covers and abuts against at least part of the outer surface of the porous structure 1 to improve the lubricity of the porous structure 1 when moving in the blood vessel.

[0075] As an alternative embodiment, the coating covers all the outer surfaces of the porous structure 1, that is, the coating is coated on all the outer surfaces of the porous structure 1. As another alternative embodiment, the coating covers part of the outer surface of the porous structure 1, that is, the porous structure 1 is only coated with the coating on part of the outer surface. For example, the coating can cover the area of the outer surface of the porous structure 1 except the distal end.

[0076] In summary, the present invention provides a medical guide wire. The distal end of the guide wire is provided with a porous structure 1 having pores 3, which can improve the softness of the distal end of the guide wire, reduce the hardness of the head end of the guide wire, prevent the head end of the guide wire from piercing the blood vessel, and can also make the guide wire easy to bend and pass through tortuous blood vessels, contribute to the guide wire reaching the lesion site smoothly, and improve the success rate of the operation.

[0077] In addition, the material of the porous structure 1 can be selected from any suitable polymer material with thermoplasticity, biocompatibility and flexibility at human body temperature. The preparation material of the porous structure 1 is preferably a thermoplastic polymer material, such as a combination of one or more of polyurethane, polyolefin and polyester. Such materials can be shaped by heating, are easy to form and have a larger bending angle, and can have good shape retention at room temperature, improving the shaping ability and shape retention ability of the guide wire.

[0078] The above description is only a description of the preferred embodiments of the present invention and does not limit the scope of the present invention in any way. Any changes and modifications made by those of ordinary skill in the art of the present invention based on the above disclosure shall fall within the protection scope of the present invention.

Claims

1. A medical guide wire, characterized in that, It includes a porous structure and a core wire connected in sequence from the distal end to the proximal end, and a number of pores are provided in the porous structure.

2. The medical guide wire according to claim 1, characterized in that, At least part of the pores are distributed in the distal region of the porous structure.

3. The medical guide wire according to claim 2, wherein The pores are also distributed in the proximal region and / or the middle region of the porous structure.

4. The medical guide wire according to claim 1, characterized in that, The inner diameters of at least part of the pores are different.

5. The medical guide wire according to claim 4, wherein In the direction of the axis of the porous structure from the distal end to the proximal end, the inner diameter of the pores gradually decreases. And / or, in the direction of the cross-section of the porous structure from the inside to the outside, the inner diameter of the pores gradually decreases.

6. The medical guide wire according to any one of claims 1-5, characterized in that, All the pores are of an elliptical structure, and the size of the pores in the radial direction of the porous structure is larger than the size of the pores in the axial direction of the porous structure.

7. The medical guide wire according to any one of claims 1-5, characterized in that, The porosity of the porous structure gradually decreases in the direction of its own axis from the distal end to the proximal end, and / or the porosity of the porous structure gradually decreases in the direction of its own cross-section from the inside to the outside.

8. The medical guide wire according to any one of claims 1-5, characterized in that The distal end of the core wire extends into the porous structure and is connected to the porous structure.

9. The medical guide wire according to claim 8, characterized in that, It further includes a sheath or a coating, and the sheath or the coating covers and abuts against at least part of the outer surface of the porous structure.

10. The medical guide wire according to claim 9, wherein, The sheath or the coating covers all the outer surfaces of the porous structure, or the sheath or the coating covers the area of the outer surface of the porous structure except the distal end.

11. The medical guide wire according to claim 10, characterized in that, The length of the region where the porous structure extends out of the sheath in its own axial direction is less than 50 mm.

12. The medical guide wire according to any one of claims 1-5, characterized in that, The porosity of the porous structure is 30% - 80%, and / or the inner diameter of the pores is 1 - 900 μm.

13. The medical guide wire according to any one of claims 1-5, characterized in that, The total length of the porous structure and the core wire in the axial direction of the porous structure is 80 cm - 320 cm, and the length of the porous structure in its own axial direction is 3 cm - 70 cm; the maximum outer diameter of the porous structure and the core wire is 0.008 inch - 0.038 inch.

14. The medical guide wire according to any one of claims 1-5, characterized in that, The material of the porous structure is one or a combination of polyurethane, polyolefin and polyester, and / or the material of the core wire is a polymer material or a metal material.

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